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Overview

ID MAG01880
Name HKD3_bin.82
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus Quisquiliibacterium
Species
Assembly information
Completeness (%) 68.38
Contamination (%) 0.86
GC content (%) 72.0
N50 (bp) 25,354
Genome size (bp) 3,076,902

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2882

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1012661_0 PFAM extracellular solute-binding protein family 1 K02027 - - 2.167e-202 638.0
HKD3_k127_1012661_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 452.0
HKD3_k127_1012661_10 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000006937 124.0
HKD3_k127_1012661_2 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 413.0
HKD3_k127_1012661_3 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
HKD3_k127_1012661_4 carbohydrate kinase, FGGY K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 401.0
HKD3_k127_1012661_5 3-epimerase K03079 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019324,GO:0034015,GO:0044238,GO:0044281,GO:0071704 5.1.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 361.0
HKD3_k127_1012661_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 357.0
HKD3_k127_1012661_7 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 301.0
HKD3_k127_1012661_8 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source K03077 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 306.0
HKD3_k127_1012661_9 DeoR C terminal sensor domain K06608 - - 0.000000000000000000000000000000000000000000000000798 199.0
HKD3_k127_113754_0 PFAM sulfatase K01130 - 3.1.6.1 0.0 1050.0
HKD3_k127_113754_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.708e-306 949.0
HKD3_k127_113754_10 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 451.0
HKD3_k127_113754_11 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 460.0
HKD3_k127_113754_12 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 443.0
HKD3_k127_113754_13 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 399.0
HKD3_k127_113754_14 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 392.0
HKD3_k127_113754_15 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 369.0
HKD3_k127_113754_16 NAD dependent epimerase dehydratase family protein K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 328.0
HKD3_k127_113754_17 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 297.0
HKD3_k127_113754_18 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 294.0
HKD3_k127_113754_19 RNA-binding S4 domain-containing protein K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000007214 267.0
HKD3_k127_113754_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 2.024e-220 692.0
HKD3_k127_113754_20 PFAM GCN5-related N-acetyltransferase K03824 - - 0.00000000000000000000000000000000000000000000000000000000000000000421 259.0
HKD3_k127_113754_21 PFAM lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000009852 221.0
HKD3_k127_113754_22 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000004416 188.0
HKD3_k127_113754_23 - - - - 0.0000000000000000000000000000000000000000003742 181.0
HKD3_k127_113754_24 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000008914 158.0
HKD3_k127_113754_25 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000002443 134.0
HKD3_k127_113754_26 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000002458 109.0
HKD3_k127_113754_27 - - - - 0.00000000000000000002434 102.0
HKD3_k127_113754_28 Protein of unknown function (DUF2905) - - - 0.0000000000000003481 91.0
HKD3_k127_113754_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.18e-206 654.0
HKD3_k127_113754_4 Beta-lactamase - - - 7.392e-205 655.0
HKD3_k127_113754_5 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 1.002e-196 616.0
HKD3_k127_113754_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 612.0
HKD3_k127_113754_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 565.0
HKD3_k127_113754_8 lytic transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 542.0
HKD3_k127_113754_9 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 494.0
HKD3_k127_1257023_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1451.0
HKD3_k127_1257023_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1330.0
HKD3_k127_1257023_10 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.0000000000000000000000000000000000000000000001431 183.0
HKD3_k127_1257023_11 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000001107 174.0
HKD3_k127_1257023_12 Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000007305 164.0
HKD3_k127_1257023_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 612.0
HKD3_k127_1257023_3 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 411.0
HKD3_k127_1257023_4 Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 376.0
HKD3_k127_1257023_5 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 351.0
HKD3_k127_1257023_6 xylanase chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 310.0
HKD3_k127_1257023_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003287 245.0
HKD3_k127_1257023_8 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000009081 197.0
HKD3_k127_1257023_9 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000002961 192.0
HKD3_k127_1260253_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1140.0
HKD3_k127_1260253_1 Participates in both transcription termination and antitermination K02600 - - 4.105e-244 776.0
HKD3_k127_1260253_10 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 394.0
HKD3_k127_1260253_11 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 368.0
HKD3_k127_1260253_12 mechanosensitive ion channel K03442,K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 354.0
HKD3_k127_1260253_13 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 351.0
HKD3_k127_1260253_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 328.0
HKD3_k127_1260253_15 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 319.0
HKD3_k127_1260253_16 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 317.0
HKD3_k127_1260253_17 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003638 287.0
HKD3_k127_1260253_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000182 270.0
HKD3_k127_1260253_19 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006871 267.0
HKD3_k127_1260253_2 LUD domain K18929 - - 1.058e-225 706.0
HKD3_k127_1260253_20 ornithine cyclodeaminase mu-crystallin K01750,K19743 - 1.5.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000004451 292.0
HKD3_k127_1260253_21 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000008263 261.0
HKD3_k127_1260253_22 plastoquinol--plastocyanin reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002346 259.0
HKD3_k127_1260253_23 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000003258 207.0
HKD3_k127_1260253_24 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000000001294 175.0
HKD3_k127_1260253_25 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000003019 155.0
HKD3_k127_1260253_26 TIGRFAM phasin family protein - - - 0.0000000000000000000000000000000000002183 147.0
HKD3_k127_1260253_27 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000246 140.0
HKD3_k127_1260253_28 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000006466 147.0
HKD3_k127_1260253_29 Ribosome-binding factor A - - - 0.00000000000000000005474 92.0
HKD3_k127_1260253_3 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 3.988e-214 679.0
HKD3_k127_1260253_31 - - - - 0.0000002345 62.0
HKD3_k127_1260253_4 Protein of unknown function (DUF4080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 599.0
HKD3_k127_1260253_5 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 446.0
HKD3_k127_1260253_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 447.0
HKD3_k127_1260253_7 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 458.0
HKD3_k127_1260253_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 409.0
HKD3_k127_1260253_9 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 389.0
HKD3_k127_1277962_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.553e-320 992.0
HKD3_k127_1277962_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.392e-303 944.0
HKD3_k127_1277962_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 2.626e-302 931.0
HKD3_k127_1277962_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.476e-237 739.0
HKD3_k127_1277962_4 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 590.0
HKD3_k127_1277962_5 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 462.0
HKD3_k127_1277962_6 Dehydrogenase E1 component K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000003105 189.0
HKD3_k127_1277962_7 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000004478 106.0
HKD3_k127_1280009_0 Transport of potassium into the cell K03549 - - 2.322e-280 873.0
HKD3_k127_1280009_1 osmosensitive K channel K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 327.0
HKD3_k127_1280009_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002206 268.0
HKD3_k127_1280009_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000009165 215.0
HKD3_k127_1280009_4 - - - - 0.000000000000000000000000002286 127.0
HKD3_k127_1336526_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 613.0
HKD3_k127_1336526_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 374.0
HKD3_k127_1336526_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 389.0
HKD3_k127_1336526_3 Haem-NO-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 284.0
HKD3_k127_1336526_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000001335 167.0
HKD3_k127_1336526_5 antisigma factor binding K04749,K06378 - - 0.000000000000000000000000001525 117.0
HKD3_k127_1336526_6 Heme NO binding associated - - - 0.0000000000000000000001476 113.0
HKD3_k127_1336526_7 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.00000000005553 64.0
HKD3_k127_1369813_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 5.188e-217 680.0
HKD3_k127_1369813_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 525.0
HKD3_k127_1369813_2 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 404.0
HKD3_k127_1369813_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 351.0
HKD3_k127_1369813_4 PFAM alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 304.0
HKD3_k127_1369813_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000001855 273.0
HKD3_k127_1369813_6 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000006074 257.0
HKD3_k127_1391733_0 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 2.879e-235 743.0
HKD3_k127_1391733_1 Tripartite tricarboxylate transporter TctA family - - - 3.377e-235 736.0
HKD3_k127_1391733_10 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000004909 143.0
HKD3_k127_1391733_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 621.0
HKD3_k127_1391733_3 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 482.0
HKD3_k127_1391733_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 424.0
HKD3_k127_1391733_5 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 346.0
HKD3_k127_1391733_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 343.0
HKD3_k127_1391733_7 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 334.0
HKD3_k127_1391733_8 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002133 269.0
HKD3_k127_1391733_9 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.000000000000000000000000000000000000000000008439 175.0
HKD3_k127_1395365_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.892e-217 690.0
HKD3_k127_1395365_1 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 557.0
HKD3_k127_1395365_2 alcohol dehydrogenase K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 463.0
HKD3_k127_1395365_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 360.0
HKD3_k127_1395365_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 357.0
HKD3_k127_1395365_5 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.00000000000000000000000000000000000000004745 161.0
HKD3_k127_1472435_0 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 1.319e-242 774.0
HKD3_k127_1472435_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 600.0
HKD3_k127_1472435_10 NmrA-like family K07118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 333.0
HKD3_k127_1472435_11 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 317.0
HKD3_k127_1472435_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
HKD3_k127_1472435_13 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000003387 143.0
HKD3_k127_1472435_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 606.0
HKD3_k127_1472435_3 Domain of unknown function DUF21 K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 595.0
HKD3_k127_1472435_4 Major Facilitator K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 578.0
HKD3_k127_1472435_5 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 564.0
HKD3_k127_1472435_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 396.0
HKD3_k127_1472435_7 Catechol dioxygenase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 373.0
HKD3_k127_1472435_8 Coenzyme A transferase K01032 - 2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 357.0
HKD3_k127_1472435_9 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01031 - 2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 356.0
HKD3_k127_150077_0 Oxidoreductase FAD-binding domain K00351 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 578.0
HKD3_k127_150077_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003315 269.0
HKD3_k127_150077_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000616 236.0
HKD3_k127_150077_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000007102 215.0
HKD3_k127_150077_4 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000007647 139.0
HKD3_k127_150077_5 PFAM CBS domain containing protein - - - 0.00000000000000000000003807 105.0
HKD3_k127_150077_6 PFAM acyl-coA-binding protein, ACBP - - - 0.000000000000000004608 87.0
HKD3_k127_156226_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1702.0
HKD3_k127_156226_1 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 2.401e-279 868.0
HKD3_k127_156226_10 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 359.0
HKD3_k127_156226_11 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 325.0
HKD3_k127_156226_12 Major Facilitator Superfamily K19577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005399 290.0
HKD3_k127_156226_13 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 264.0
HKD3_k127_156226_14 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002132 250.0
HKD3_k127_156226_15 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001601 271.0
HKD3_k127_156226_16 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006469 259.0
HKD3_k127_156226_17 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.000000000000000000000000000000000000000000000000000000000000162 216.0
HKD3_k127_156226_18 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000004509 202.0
HKD3_k127_156226_19 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000007439 185.0
HKD3_k127_156226_2 AMP-binding enzyme - - - 1.72e-274 854.0
HKD3_k127_156226_20 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000001279 186.0
HKD3_k127_156226_21 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000001514 174.0
HKD3_k127_156226_22 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000001368 166.0
HKD3_k127_156226_23 Rubredoxin - - - 0.00000000000000000000001937 109.0
HKD3_k127_156226_24 Domain of unknown function (DUF4136) - - - 0.0000000000000000001643 97.0
HKD3_k127_156226_25 - - - - 0.000000000000001437 80.0
HKD3_k127_156226_3 D-aminoacylase domain protein K06015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.81 1.892e-231 725.0
HKD3_k127_156226_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 605.0
HKD3_k127_156226_5 helix-turn-helix- domain containing protein, AraC type K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 561.0
HKD3_k127_156226_6 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 462.0
HKD3_k127_156226_7 aminopeptidase N K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 417.0
HKD3_k127_156226_8 Convertase P-domain protein K20755 - 3.4.21.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 395.0
HKD3_k127_156226_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 361.0
HKD3_k127_1572759_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 630.0
HKD3_k127_1572759_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 567.0
HKD3_k127_1572759_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 363.0
HKD3_k127_1572759_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 361.0
HKD3_k127_1572759_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000001029 221.0
HKD3_k127_1572759_5 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000000279 217.0
HKD3_k127_1572759_6 - - - - 0.000000000000000000000000000000000000000002839 166.0
HKD3_k127_1572759_7 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000001241 154.0
HKD3_k127_1582122_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.008e-304 950.0
HKD3_k127_1582122_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 505.0
HKD3_k127_1582122_2 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 357.0
HKD3_k127_1582122_3 Transcriptional regulator K07734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 329.0
HKD3_k127_1582122_4 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 305.0
HKD3_k127_1582122_5 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000002337 211.0
HKD3_k127_1582122_6 - - - - 0.000000000000000000000000000000000000000000000000000008698 201.0
HKD3_k127_1582122_7 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000003942 179.0
HKD3_k127_1644640_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1139.0
HKD3_k127_1644640_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.62e-321 998.0
HKD3_k127_1644640_10 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 633.0
HKD3_k127_1644640_11 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 614.0
HKD3_k127_1644640_12 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 604.0
HKD3_k127_1644640_13 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 559.0
HKD3_k127_1644640_14 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 553.0
HKD3_k127_1644640_15 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 534.0
HKD3_k127_1644640_16 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 494.0
HKD3_k127_1644640_17 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 508.0
HKD3_k127_1644640_18 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 467.0
HKD3_k127_1644640_19 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 503.0
HKD3_k127_1644640_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.362e-290 914.0
HKD3_k127_1644640_20 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 462.0
HKD3_k127_1644640_21 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 436.0
HKD3_k127_1644640_22 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 443.0
HKD3_k127_1644640_23 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 448.0
HKD3_k127_1644640_24 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 432.0
HKD3_k127_1644640_25 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 372.0
HKD3_k127_1644640_26 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 353.0
HKD3_k127_1644640_27 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 338.0
HKD3_k127_1644640_28 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 306.0
HKD3_k127_1644640_29 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 282.0
HKD3_k127_1644640_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.152e-258 810.0
HKD3_k127_1644640_30 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000006552 265.0
HKD3_k127_1644640_31 Type IV pilus biogenesis K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007066 272.0
HKD3_k127_1644640_32 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000002184 254.0
HKD3_k127_1644640_33 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008923 246.0
HKD3_k127_1644640_34 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000001774 248.0
HKD3_k127_1644640_35 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000006525 218.0
HKD3_k127_1644640_36 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000009255 218.0
HKD3_k127_1644640_37 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000004368 216.0
HKD3_k127_1644640_38 peptidase K06194 - - 0.0000000000000000000000000000000000000000002176 171.0
HKD3_k127_1644640_39 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000000000000000004384 157.0
HKD3_k127_1644640_4 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 1.078e-246 780.0
HKD3_k127_1644640_40 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000001369 142.0
HKD3_k127_1644640_41 protein conserved in bacteria K09937 - - 0.0000000001148 67.0
HKD3_k127_1644640_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.535e-217 680.0
HKD3_k127_1644640_6 Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc K00975 - 2.7.7.27 7.117e-209 657.0
HKD3_k127_1644640_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.538e-204 672.0
HKD3_k127_1644640_8 ABC transporter K02056 - 3.6.3.17 5.855e-203 674.0
HKD3_k127_1644640_9 Belongs to the glycosyl hydrolase 57 family - - - 3.727e-202 644.0
HKD3_k127_1656383_0 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 1.09e-309 994.0
HKD3_k127_1656383_1 Male sterility protein - - - 4.019e-305 948.0
HKD3_k127_1656383_10 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit K00342,K05561,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 472.0
HKD3_k127_1656383_11 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 424.0
HKD3_k127_1656383_12 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 431.0
HKD3_k127_1656383_13 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 400.0
HKD3_k127_1656383_14 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 409.0
HKD3_k127_1656383_15 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 383.0
HKD3_k127_1656383_16 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 387.0
HKD3_k127_1656383_17 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 379.0
HKD3_k127_1656383_18 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 358.0
HKD3_k127_1656383_19 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 353.0
HKD3_k127_1656383_2 GMC oxidoreductase - - - 3.01e-237 752.0
HKD3_k127_1656383_20 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 319.0
HKD3_k127_1656383_21 Bacterial transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 291.0
HKD3_k127_1656383_22 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005304 282.0
HKD3_k127_1656383_23 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009338,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001286 289.0
HKD3_k127_1656383_24 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000000003859 217.0
HKD3_k127_1656383_25 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000002877 209.0
HKD3_k127_1656383_26 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000003285 215.0
HKD3_k127_1656383_27 - - - - 0.0000000000000000000000000000000000000000000000000008564 193.0
HKD3_k127_1656383_28 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000001156 184.0
HKD3_k127_1656383_29 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000009052 199.0
HKD3_k127_1656383_3 Amidohydrolase family K15358 - 3.5.2.18 1.841e-212 664.0
HKD3_k127_1656383_30 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000008797 185.0
HKD3_k127_1656383_31 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000008375 170.0
HKD3_k127_1656383_32 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000003421 150.0
HKD3_k127_1656383_33 Copper resistance protein D - - - 0.0000000000000000000000000000000000009591 144.0
HKD3_k127_1656383_34 PFAM poly granule associated family protein - - - 0.00000000000000000000000000000000001974 140.0
HKD3_k127_1656383_35 - - - - 0.00000000000000000000000000000000008031 142.0
HKD3_k127_1656383_36 PFAM acyl-coA-binding protein, ACBP - - - 0.0000000000000000000000000000000002684 136.0
HKD3_k127_1656383_37 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.0000000000000000000000000000000004937 150.0
HKD3_k127_1656383_38 COG1320 Multisubunit Na H antiporter, MnhG subunit K05564 - - 0.0000000000000000000000000002391 122.0
HKD3_k127_1656383_39 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05563 - - 0.0000000000000000000000006141 113.0
HKD3_k127_1656383_4 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 2.858e-209 688.0
HKD3_k127_1656383_40 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000001128 86.0
HKD3_k127_1656383_41 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000005013 81.0
HKD3_k127_1656383_42 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000093 84.0
HKD3_k127_1656383_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 2.605e-200 647.0
HKD3_k127_1656383_6 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 576.0
HKD3_k127_1656383_7 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 533.0
HKD3_k127_1656383_8 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 540.0
HKD3_k127_1656383_9 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 499.0
HKD3_k127_167646_0 PQQ-like domain - - - 4.436e-262 818.0
HKD3_k127_167646_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 450.0
HKD3_k127_167646_10 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000004214 60.0
HKD3_k127_167646_11 Glyoxalase-like domain - - - 0.000000003612 61.0
HKD3_k127_167646_2 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 371.0
HKD3_k127_167646_3 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 332.0
HKD3_k127_167646_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 292.0
HKD3_k127_167646_5 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000005443 227.0
HKD3_k127_167646_6 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000004361 214.0
HKD3_k127_167646_7 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000001141 168.0
HKD3_k127_167646_8 membrane - - - 0.00000000000000000000000001486 114.0
HKD3_k127_167646_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000007794 108.0
HKD3_k127_1737215_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 5.141e-320 995.0
HKD3_k127_1737215_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 493.0
HKD3_k127_1737215_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 354.0
HKD3_k127_1737215_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 342.0
HKD3_k127_1737215_4 - - - - 0.0000398 49.0
HKD3_k127_1751602_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 0.0 1180.0
HKD3_k127_1751602_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.341e-252 793.0
HKD3_k127_1751602_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 361.0
HKD3_k127_1751602_11 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 315.0
HKD3_k127_1751602_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 321.0
HKD3_k127_1751602_13 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000136 227.0
HKD3_k127_1751602_14 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000000000005216 235.0
HKD3_k127_1751602_15 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000121 201.0
HKD3_k127_1751602_16 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000062 215.0
HKD3_k127_1751602_17 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000002192 168.0
HKD3_k127_1751602_18 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000003137 168.0
HKD3_k127_1751602_19 - - - - 0.0000000000000000000000000000000000000000002744 176.0
HKD3_k127_1751602_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.384e-241 761.0
HKD3_k127_1751602_20 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000006018 156.0
HKD3_k127_1751602_21 OsmC-like protein - - - 0.0000000000000000000000000000000000000004234 169.0
HKD3_k127_1751602_22 membrane - - - 0.00000000000000000000000000006112 120.0
HKD3_k127_1751602_24 Domain of unknown function (DUF4214) - - - 0.0000000000000000000000127 109.0
HKD3_k127_1751602_25 YHYH protein - - - 0.00000000000006255 74.0
HKD3_k127_1751602_3 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.203e-235 737.0
HKD3_k127_1751602_4 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 1.702e-207 664.0
HKD3_k127_1751602_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 575.0
HKD3_k127_1751602_6 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 576.0
HKD3_k127_1751602_7 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 523.0
HKD3_k127_1751602_8 Cytochrome P450 K21034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 514.0
HKD3_k127_1751602_9 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 434.0
HKD3_k127_1766221_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.557e-255 800.0
HKD3_k127_1766221_1 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 552.0
HKD3_k127_1766221_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 497.0
HKD3_k127_1766221_3 peptidase dimerisation domain protein K01451 - 3.5.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 453.0
HKD3_k127_1766221_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 441.0
HKD3_k127_1766221_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000002828 177.0
HKD3_k127_1839486_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1152.0
HKD3_k127_1839486_1 Thymidine phosphorylase K00758 - 2.4.2.4 1.691e-212 671.0
HKD3_k127_1839486_2 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 339.0
HKD3_k127_1839486_3 HIT domain - - - 0.0000000000000000000000000000000000000000000000000003072 188.0
HKD3_k127_1839486_4 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000006882 125.0
HKD3_k127_1839486_5 PFAM CHRD domain containing protein - - - 0.000000000000000000000000000001172 126.0
HKD3_k127_1839486_6 SnoaL-like domain - - - 0.0000000000000000000000001316 110.0
HKD3_k127_1895216_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 1.739e-304 947.0
HKD3_k127_1895216_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.328e-223 700.0
HKD3_k127_1895216_2 Sigma-54 interaction domain K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 542.0
HKD3_k127_1895216_3 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 376.0
HKD3_k127_1895216_4 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001108 239.0
HKD3_k127_1895216_5 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000001575 239.0
HKD3_k127_1895216_6 - K06950 - - 0.00000006833 64.0
HKD3_k127_1920232_0 Amidohydrolase family - - - 6.271e-258 804.0
HKD3_k127_1920232_1 DNA polymerase X family K02347 - - 4.009e-250 786.0
HKD3_k127_1920232_2 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 366.0
HKD3_k127_1920232_3 Flavocytochrome c sulphide dehydrogenase, flavin-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 373.0
HKD3_k127_1920232_4 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003855 279.0
HKD3_k127_1920232_5 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000009446 171.0
HKD3_k127_1920232_6 cytochrome - - - 0.0000000000003516 76.0
HKD3_k127_1920232_7 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000004526 63.0
HKD3_k127_2086861_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169 - 0.0 1660.0
HKD3_k127_2086861_1 cytosine deaminase K01485 - 3.5.4.1 3.293e-217 681.0
HKD3_k127_2086861_10 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 448.0
HKD3_k127_2086861_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 388.0
HKD3_k127_2086861_12 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 381.0
HKD3_k127_2086861_13 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 383.0
HKD3_k127_2086861_14 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 375.0
HKD3_k127_2086861_15 ABC transporter substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 356.0
HKD3_k127_2086861_16 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 345.0
HKD3_k127_2086861_17 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 323.0
HKD3_k127_2086861_18 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 305.0
HKD3_k127_2086861_19 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 301.0
HKD3_k127_2086861_2 Glucose inhibited division protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 597.0
HKD3_k127_2086861_20 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
HKD3_k127_2086861_21 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004445 283.0
HKD3_k127_2086861_22 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000008975 273.0
HKD3_k127_2086861_23 Shikimate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001585 253.0
HKD3_k127_2086861_24 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000003606 92.0
HKD3_k127_2086861_3 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 591.0
HKD3_k127_2086861_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015318,GO:0015679,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030288,GO:0030313,GO:0031975,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1990169 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 548.0
HKD3_k127_2086861_5 basic membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 532.0
HKD3_k127_2086861_6 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 505.0
HKD3_k127_2086861_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 484.0
HKD3_k127_2086861_8 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 469.0
HKD3_k127_2086861_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 453.0
HKD3_k127_216161_0 belongs to the aldehyde dehydrogenase family K22187 - - 1.809e-235 736.0
HKD3_k127_216161_1 Oxidoreductase domain protein - - - 1.671e-197 623.0
HKD3_k127_216161_2 Protein of unknown function (DUF993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 582.0
HKD3_k127_216161_3 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 510.0
HKD3_k127_216161_4 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 473.0
HKD3_k127_216161_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000001323 163.0
HKD3_k127_216161_6 dihydroorotate dehydrogenase activity K02823,K17828 - 1.3.1.14 0.000000000000000000000000000000001148 139.0
HKD3_k127_233404_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0 1023.0
HKD3_k127_233404_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 4.719e-233 750.0
HKD3_k127_233404_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000002037 222.0
HKD3_k127_233404_11 Phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000003275 218.0
HKD3_k127_233404_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000001276 214.0
HKD3_k127_233404_13 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000006131 199.0
HKD3_k127_233404_14 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000009385 192.0
HKD3_k127_233404_15 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000003366 177.0
HKD3_k127_233404_16 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000009177 169.0
HKD3_k127_233404_17 Protein of unknown function (DUF541) - - - 0.000000000000000000000000003048 121.0
HKD3_k127_233404_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.575e-224 702.0
HKD3_k127_233404_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 518.0
HKD3_k127_233404_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 489.0
HKD3_k127_233404_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 493.0
HKD3_k127_233404_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 346.0
HKD3_k127_233404_7 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 325.0
HKD3_k127_233404_8 riboflavin synthase alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002329 283.0
HKD3_k127_233404_9 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000006063 228.0
HKD3_k127_2452124_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 474.0
HKD3_k127_2452124_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 361.0
HKD3_k127_2452124_10 - - - - 0.000000000000367 78.0
HKD3_k127_2452124_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 282.0
HKD3_k127_2452124_3 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000006466 208.0
HKD3_k127_2452124_4 DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000007136 187.0
HKD3_k127_2452124_5 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000006488 182.0
HKD3_k127_2452124_6 Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000007497 163.0
HKD3_k127_2452124_7 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000007826 152.0
HKD3_k127_2452124_8 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000000002715 135.0
HKD3_k127_2452124_9 Belongs to the universal stress protein A family - - - 0.00000000000004348 78.0
HKD3_k127_2455616_0 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 523.0
HKD3_k127_2455616_1 ATPases associated with a variety of cellular activities K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 479.0
HKD3_k127_2455616_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 433.0
HKD3_k127_2455616_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 305.0
HKD3_k127_2455616_4 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009106 241.0
HKD3_k127_2455616_5 - - - - 0.00000000000000000000001499 113.0
HKD3_k127_2481920_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 7.989e-275 857.0
HKD3_k127_2481920_1 COG1180 Pyruvate-formate lyase-activating enzyme K20449 - 1.3.7.1 1.291e-225 726.0
HKD3_k127_2481920_2 Amidohydrolase family K15358 - 3.5.2.18 4.835e-209 655.0
HKD3_k127_2481920_3 PFAM Extracellular ligand-binding receptor K01999 - - 1.786e-194 613.0
HKD3_k127_2481920_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 387.0
HKD3_k127_2481920_5 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 358.0
HKD3_k127_2481920_6 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 340.0
HKD3_k127_2481920_7 Amino acid synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 326.0
HKD3_k127_2481920_8 Amino acid synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 294.0
HKD3_k127_2481920_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001896 286.0
HKD3_k127_2497309_0 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 3.076e-285 892.0
HKD3_k127_2497309_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 598.0
HKD3_k127_2497309_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001177 266.0
HKD3_k127_2497309_11 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000329 213.0
HKD3_k127_2497309_12 - - - - 0.0000000000000002168 81.0
HKD3_k127_2497309_13 - - - - 0.000000000005182 73.0
HKD3_k127_2497309_2 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 553.0
HKD3_k127_2497309_3 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 530.0
HKD3_k127_2497309_4 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 506.0
HKD3_k127_2497309_5 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 499.0
HKD3_k127_2497309_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 497.0
HKD3_k127_2497309_7 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 406.0
HKD3_k127_2497309_8 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 358.0
HKD3_k127_2497309_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 355.0
HKD3_k127_256867_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1500.0
HKD3_k127_256867_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.34e-292 913.0
HKD3_k127_256867_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 405.0
HKD3_k127_256867_3 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 366.0
HKD3_k127_256867_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
HKD3_k127_256867_5 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001468 264.0
HKD3_k127_256867_6 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 243.0
HKD3_k127_2572844_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1273.0
HKD3_k127_2572844_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 601.0
HKD3_k127_2572844_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 557.0
HKD3_k127_2572844_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 549.0
HKD3_k127_2572844_4 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 460.0
HKD3_k127_2572844_5 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 453.0
HKD3_k127_2572844_6 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 438.0
HKD3_k127_2572844_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 305.0
HKD3_k127_2572844_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000000746 184.0
HKD3_k127_2593114_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1129.0
HKD3_k127_2593114_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 7.746e-281 866.0
HKD3_k127_2593114_2 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 9.062e-250 780.0
HKD3_k127_2593114_3 GTP cyclohydrolase N terminal - - - 1.435e-242 764.0
HKD3_k127_2593114_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005955 280.0
HKD3_k127_2593114_5 FR47-like protein - - - 0.00000000000000000000000000000000000162 149.0
HKD3_k127_2593114_6 Protein of unknown function (DUF1688) - - - 0.000000000000000000000000000007711 127.0
HKD3_k127_2593114_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000002517 100.0
HKD3_k127_2593114_8 TIGRFAM phasin family protein - - - 0.000000000000000000005938 102.0
HKD3_k127_2599252_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1013.0
HKD3_k127_2599252_1 RecG wedge domain K03655 - 3.6.4.12 2.449e-247 786.0
HKD3_k127_2599252_10 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 282.0
HKD3_k127_2599252_11 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001093 292.0
HKD3_k127_2599252_12 Belongs to the asparaginase 1 family K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 268.0
HKD3_k127_2599252_13 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000000000001149 246.0
HKD3_k127_2599252_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000007092 233.0
HKD3_k127_2599252_15 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.000000000000000000000000000000000000000000000000000001411 215.0
HKD3_k127_2599252_16 endoribonuclease - - - 0.000000000000000000000000000000000000000000001164 169.0
HKD3_k127_2599252_17 TM2 domain - - - 0.00000000000000002964 89.0
HKD3_k127_2599252_2 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 2.01e-203 653.0
HKD3_k127_2599252_3 Fatty acid desaturase K00496 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 505.0
HKD3_k127_2599252_4 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 494.0
HKD3_k127_2599252_5 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 468.0
HKD3_k127_2599252_6 LysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 444.0
HKD3_k127_2599252_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 452.0
HKD3_k127_2599252_8 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 368.0
HKD3_k127_2599252_9 Lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 319.0
HKD3_k127_2623471_0 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 5.785e-230 715.0
HKD3_k127_2623471_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 1.105e-216 683.0
HKD3_k127_2623471_10 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 511.0
HKD3_k127_2623471_11 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 456.0
HKD3_k127_2623471_12 PFAM aminotransferase class V K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 450.0
HKD3_k127_2623471_13 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 452.0
HKD3_k127_2623471_14 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 432.0
HKD3_k127_2623471_15 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 404.0
HKD3_k127_2623471_16 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 333.0
HKD3_k127_2623471_17 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000016 240.0
HKD3_k127_2623471_18 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000007242 201.0
HKD3_k127_2623471_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000007392 176.0
HKD3_k127_2623471_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K01706 - 4.2.1.40 7.869e-200 634.0
HKD3_k127_2623471_20 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000000002154 167.0
HKD3_k127_2623471_21 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000002732 153.0
HKD3_k127_2623471_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 581.0
HKD3_k127_2623471_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 555.0
HKD3_k127_2623471_5 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 539.0
HKD3_k127_2623471_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 536.0
HKD3_k127_2623471_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 526.0
HKD3_k127_2623471_8 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 499.0
HKD3_k127_2623471_9 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 483.0
HKD3_k127_264055_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 3.08e-209 664.0
HKD3_k127_264055_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 576.0
HKD3_k127_264055_2 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 569.0
HKD3_k127_264055_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 386.0
HKD3_k127_264055_4 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 354.0
HKD3_k127_264055_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 297.0
HKD3_k127_264055_6 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000002366 120.0
HKD3_k127_264055_7 PrcB C-terminal - - - 0.000000000004899 78.0
HKD3_k127_2651485_0 COG0480 Translation elongation factors (GTPases) K02355 - - 5.257e-302 939.0
HKD3_k127_2651485_1 ABC transporter K15738 - - 3.446e-229 728.0
HKD3_k127_2651485_10 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 353.0
HKD3_k127_2651485_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 312.0
HKD3_k127_2651485_12 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 321.0
HKD3_k127_2651485_13 SbmA/BacA-like family K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 308.0
HKD3_k127_2651485_14 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 296.0
HKD3_k127_2651485_15 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 261.0
HKD3_k127_2651485_16 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006883 271.0
HKD3_k127_2651485_17 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
HKD3_k127_2651485_18 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008945 244.0
HKD3_k127_2651485_19 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000002888 182.0
HKD3_k127_2651485_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.545e-200 676.0
HKD3_k127_2651485_20 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000023 168.0
HKD3_k127_2651485_21 Protein of unknown function (DUF3579) - - - 0.0000000000000000000000000000001719 126.0
HKD3_k127_2651485_22 Sigma-70 region 2 K03088 - - 0.000000000000000000000001666 111.0
HKD3_k127_2651485_3 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 561.0
HKD3_k127_2651485_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 525.0
HKD3_k127_2651485_5 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 526.0
HKD3_k127_2651485_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 473.0
HKD3_k127_2651485_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 475.0
HKD3_k127_2651485_8 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 443.0
HKD3_k127_2651485_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 377.0
HKD3_k127_2690895_0 Belongs to the citrate synthase family K01659 - 2.3.3.5 2.341e-231 719.0
HKD3_k127_2690895_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 563.0
HKD3_k127_2690895_2 MmgE/PrpD family K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 507.0
HKD3_k127_2690895_3 Phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 477.0
HKD3_k127_2690895_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 375.0
HKD3_k127_2690895_5 GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 361.0
HKD3_k127_2690895_6 Signal peptide protein - - - 0.0000000000000000000001308 115.0
HKD3_k127_2700397_0 GTP-binding protein K06207 - - 5.4e-323 1000.0
HKD3_k127_2700397_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.67e-319 988.0
HKD3_k127_2700397_10 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 365.0
HKD3_k127_2700397_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 333.0
HKD3_k127_2700397_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 316.0
HKD3_k127_2700397_13 ATPases associated with a variety of cellular activities K02010,K02017,K11072 - 3.6.3.29,3.6.3.30,3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 334.0
HKD3_k127_2700397_14 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 292.0
HKD3_k127_2700397_15 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.000000000000000000000000000000000000000000000000000004355 206.0
HKD3_k127_2700397_16 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000002447 160.0
HKD3_k127_2700397_17 (Lipo)protein - - - 0.000000000000000000000000000000000001115 151.0
HKD3_k127_2700397_18 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000000001504 145.0
HKD3_k127_2700397_19 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000002656 112.0
HKD3_k127_2700397_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.116e-304 972.0
HKD3_k127_2700397_20 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000007033 103.0
HKD3_k127_2700397_21 PIN domain - - - 0.00000000000000000004083 102.0
HKD3_k127_2700397_22 Protein of unknown function (DUF3460) - - - 0.000000000000678 70.0
HKD3_k127_2700397_23 SMART Water Stress and Hypersensitive response - - - 0.0000001281 64.0
HKD3_k127_2700397_3 Sulfate permease family K03321 - - 1.306e-213 677.0
HKD3_k127_2700397_4 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 620.0
HKD3_k127_2700397_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 587.0
HKD3_k127_2700397_6 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 571.0
HKD3_k127_2700397_7 PFAM Aminotransferase class I and II K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 554.0
HKD3_k127_2700397_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 465.0
HKD3_k127_2700397_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 389.0
HKD3_k127_2704654_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.019e-271 847.0
HKD3_k127_2704654_1 type II secretion system protein E K02454 - - 9.693e-251 782.0
HKD3_k127_2704654_10 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 428.0
HKD3_k127_2704654_11 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 388.0
HKD3_k127_2704654_12 aldo keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 366.0
HKD3_k127_2704654_13 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 358.0
HKD3_k127_2704654_14 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009137 268.0
HKD3_k127_2704654_15 General secretion pathway protein L K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 280.0
HKD3_k127_2704654_16 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008519 252.0
HKD3_k127_2704654_17 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000573 246.0
HKD3_k127_2704654_18 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000001425 229.0
HKD3_k127_2704654_19 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000223 241.0
HKD3_k127_2704654_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 3.026e-231 726.0
HKD3_k127_2704654_20 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000001173 231.0
HKD3_k127_2704654_21 General Secretory Pathway K02463 - - 0.00000000000000000000000000000000000000000000000000000000000000001484 234.0
HKD3_k127_2704654_22 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000111 211.0
HKD3_k127_2704654_23 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000009008 215.0
HKD3_k127_2704654_24 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000004836 205.0
HKD3_k127_2704654_25 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000003942 195.0
HKD3_k127_2704654_26 general secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000007877 195.0
HKD3_k127_2704654_27 general secretion pathway protein K02457 - - 0.000000000000000000000000000000000000000002097 168.0
HKD3_k127_2704654_28 general secretion pathway protein K02459 - - 0.0000000000000000000000000000000004238 144.0
HKD3_k127_2704654_29 Type II secretion system (T2SS), protein I K02458 - - 0.000000000000000000000000000009436 128.0
HKD3_k127_2704654_3 general secretion pathway protein D K02453 - - 2.127e-222 721.0
HKD3_k127_2704654_30 General secretion pathway K02462 - - 0.000000000000000000000000000473 129.0
HKD3_k127_2704654_32 Protein of unknown function (DUF1232) - - - 0.000000000000001048 83.0
HKD3_k127_2704654_4 COG0183 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 565.0
HKD3_k127_2704654_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 471.0
HKD3_k127_2704654_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 456.0
HKD3_k127_2704654_7 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 456.0
HKD3_k127_2704654_8 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 449.0
HKD3_k127_2704654_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 427.0
HKD3_k127_2734826_0 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.737e-255 791.0
HKD3_k127_2734826_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 420.0
HKD3_k127_2734826_10 YGGT family K02221 - - 0.00000000000007507 72.0
HKD3_k127_2734826_2 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 404.0
HKD3_k127_2734826_3 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003684 297.0
HKD3_k127_2734826_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000009674 214.0
HKD3_k127_2734826_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000001618 201.0
HKD3_k127_2734826_6 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000001408 188.0
HKD3_k127_2734826_7 Thioredoxin-like - - - 0.000000000000000000000000000000000000001719 168.0
HKD3_k127_2734826_8 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000001421 153.0
HKD3_k127_2734826_9 Belongs to the UPF0235 family K09131 - - 0.00000000000005152 77.0
HKD3_k127_2745895_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.444e-303 949.0
HKD3_k127_2745895_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 516.0
HKD3_k127_2745895_10 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000000000000000000000000000004211 151.0
HKD3_k127_2745895_2 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 462.0
HKD3_k127_2745895_3 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 342.0
HKD3_k127_2745895_4 Transcriptional regulator K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 339.0
HKD3_k127_2745895_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001124 247.0
HKD3_k127_2745895_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000005747 232.0
HKD3_k127_2745895_7 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000001222 224.0
HKD3_k127_2745895_8 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000008345 205.0
HKD3_k127_2745895_9 Nitrogen regulatory protein P-II K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000008936 196.0
HKD3_k127_2756524_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 7.67e-309 954.0
HKD3_k127_2756524_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.299e-245 795.0
HKD3_k127_2756524_10 Transcriptional regulator, Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000004048 239.0
HKD3_k127_2756524_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - 0.000000000000000000000000000000000000006925 154.0
HKD3_k127_2756524_12 Major facilitator superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000848 164.0
HKD3_k127_2756524_13 Cytochrome c K08738 - - 0.000000000000000000000000000000002813 131.0
HKD3_k127_2756524_14 Invasion gene expression up-regulator SirB - - - 0.0000000000000000000000000000001662 128.0
HKD3_k127_2756524_15 redox protein, regulator of disulfide bond formation - - - 0.00000000000007855 82.0
HKD3_k127_2756524_16 cytochrome - - - 0.0000000005647 74.0
HKD3_k127_2756524_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 627.0
HKD3_k127_2756524_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 462.0
HKD3_k127_2756524_4 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 467.0
HKD3_k127_2756524_5 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 401.0
HKD3_k127_2756524_6 Outer membrane protein beta-barrel family K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 379.0
HKD3_k127_2756524_7 Pfam SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 334.0
HKD3_k127_2756524_8 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 287.0
HKD3_k127_2756524_9 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001677 281.0
HKD3_k127_297488_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1095.0
HKD3_k127_297488_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1019.0
HKD3_k127_297488_10 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007756 272.0
HKD3_k127_297488_11 LysE type translocator - - - 0.0000000000000000000000000000000000000004123 156.0
HKD3_k127_297488_12 Small multidrug resistance - - - 0.0000000000000000000000000000000006341 134.0
HKD3_k127_297488_13 Serine threonine protein kinase - - - 0.00000000000000000000000004309 113.0
HKD3_k127_297488_2 Molecular chaperone. Has ATPase activity K04079 - - 3.141e-236 738.0
HKD3_k127_297488_3 ABC-type sugar transport system, periplasmic component K02027 - - 1.319e-207 654.0
HKD3_k127_297488_4 Transcriptional regulator with HTH domain and aminotransferase domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 569.0
HKD3_k127_297488_5 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 509.0
HKD3_k127_297488_6 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 488.0
HKD3_k127_297488_7 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 484.0
HKD3_k127_297488_8 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 397.0
HKD3_k127_297488_9 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002088 290.0
HKD3_k127_3054606_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.616e-280 879.0
HKD3_k127_3054606_1 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.057e-248 801.0
HKD3_k127_3054606_10 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000716 183.0
HKD3_k127_3054606_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002609 183.0
HKD3_k127_3054606_12 - - - - 0.00000000001042 78.0
HKD3_k127_3054606_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.808e-239 751.0
HKD3_k127_3054606_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 550.0
HKD3_k127_3054606_4 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 511.0
HKD3_k127_3054606_5 Catalase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 364.0
HKD3_k127_3054606_6 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 351.0
HKD3_k127_3054606_7 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 343.0
HKD3_k127_3054606_8 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000009814 226.0
HKD3_k127_3054606_9 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000005372 225.0
HKD3_k127_3060166_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 2.537e-292 921.0
HKD3_k127_3060166_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006,K01007 - 2.7.9.1,2.7.9.2 1.569e-238 744.0
HKD3_k127_3060166_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 557.0
HKD3_k127_3060166_3 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 530.0
HKD3_k127_3060166_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 494.0
HKD3_k127_3060166_5 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 372.0
HKD3_k127_3060166_6 Transport permease protein K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 357.0
HKD3_k127_3060166_7 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001039 307.0
HKD3_k127_3060166_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000006837 82.0
HKD3_k127_3096729_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.503e-210 671.0
HKD3_k127_3096729_1 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 617.0
HKD3_k127_3096729_10 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001078 265.0
HKD3_k127_3096729_11 phosphatase - - - 0.0000000000000000000000000000000000000000859 162.0
HKD3_k127_3096729_12 Protein of unknown function (DUF465) - - - 0.00000000000000000177 89.0
HKD3_k127_3096729_13 - - - - 0.00000000006253 67.0
HKD3_k127_3096729_2 PFAM AFG1-family ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 531.0
HKD3_k127_3096729_3 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 495.0
HKD3_k127_3096729_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 403.0
HKD3_k127_3096729_5 AAA domain (dynein-related subfamily) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 370.0
HKD3_k127_3096729_6 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 360.0
HKD3_k127_3096729_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 332.0
HKD3_k127_3096729_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 309.0
HKD3_k127_3096729_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001329 270.0
HKD3_k127_3192280_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1267.0
HKD3_k127_3192280_1 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 505.0
HKD3_k127_3192280_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 456.0
HKD3_k127_3192280_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 315.0
HKD3_k127_3192280_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 297.0
HKD3_k127_3192280_5 bond formation protein DsbB K03611 - - 0.0000000000000000000000000003699 122.0
HKD3_k127_3192280_6 cytochrome - - - 0.0000000000000004272 93.0
HKD3_k127_3230304_0 o-acetylhomoserine K01740 - 2.5.1.49 9.089e-229 713.0
HKD3_k127_3230304_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 322.0
HKD3_k127_3230304_2 UPF0761 membrane protein K07058 - - 0.00000000000000000000001043 109.0
HKD3_k127_3246665_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1259.0
HKD3_k127_3246665_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 7e-323 1029.0
HKD3_k127_3246665_10 Alpha beta hydrolase K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 395.0
HKD3_k127_3246665_11 Alpha beta hydrolase K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 373.0
HKD3_k127_3246665_12 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 362.0
HKD3_k127_3246665_13 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 370.0
HKD3_k127_3246665_14 Class II aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 362.0
HKD3_k127_3246665_15 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 322.0
HKD3_k127_3246665_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 337.0
HKD3_k127_3246665_17 PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000003335 244.0
HKD3_k127_3246665_18 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000004617 218.0
HKD3_k127_3246665_19 Alpha beta hydrolase K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000009839 233.0
HKD3_k127_3246665_2 Carboxyl transferase domain - - - 1.492e-222 719.0
HKD3_k127_3246665_20 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000001009 213.0
HKD3_k127_3246665_21 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000016 148.0
HKD3_k127_3246665_22 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000001295 127.0
HKD3_k127_3246665_23 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.000000000000005915 77.0
HKD3_k127_3246665_24 - - - - 0.000006136 60.0
HKD3_k127_3246665_3 PFAM SMP-30 Gluconolaconase - - - 1.457e-202 655.0
HKD3_k127_3246665_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.176e-197 621.0
HKD3_k127_3246665_5 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 553.0
HKD3_k127_3246665_6 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 512.0
HKD3_k127_3246665_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 488.0
HKD3_k127_3246665_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 414.0
HKD3_k127_3246665_9 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 383.0
HKD3_k127_3323909_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.189e-234 734.0
HKD3_k127_3323909_1 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 7.46e-205 662.0
HKD3_k127_3323909_10 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001806 268.0
HKD3_k127_3323909_11 META domain - - - 0.0000000000000000000000000000000000000000000000000000000000009105 226.0
HKD3_k127_3323909_12 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000000000000000000000008725 194.0
HKD3_k127_3323909_13 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000000000000005533 132.0
HKD3_k127_3323909_14 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000005523 117.0
HKD3_k127_3323909_15 Belongs to the ompA family K03286 - - 0.00000000001923 64.0
HKD3_k127_3323909_2 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 464.0
HKD3_k127_3323909_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 406.0
HKD3_k127_3323909_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 337.0
HKD3_k127_3323909_5 Methyltransferase K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 326.0
HKD3_k127_3323909_6 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 316.0
HKD3_k127_3323909_7 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 310.0
HKD3_k127_3323909_8 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007633 286.0
HKD3_k127_3323909_9 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000007128 259.0
HKD3_k127_3380539_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 9.532e-272 847.0
HKD3_k127_3380539_1 DNA helicase K03654 - 3.6.4.12 3.015e-244 769.0
HKD3_k127_3380539_10 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 307.0
HKD3_k127_3380539_11 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 292.0
HKD3_k127_3380539_12 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001582 279.0
HKD3_k127_3380539_13 Flavodoxin-like fold K00355,K11746,K11748 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001736 271.0
HKD3_k127_3380539_14 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000005169 237.0
HKD3_k127_3380539_15 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000001018 206.0
HKD3_k127_3380539_16 type IV pilus modification protein PilV - - - 0.0000000000000000000000000005418 118.0
HKD3_k127_3380539_17 Belongs to the universal stress protein A family - - - 0.00000000000001002 84.0
HKD3_k127_3380539_2 AMP-binding enzyme C-terminal domain K00666 - - 7.949e-222 704.0
HKD3_k127_3380539_3 Extracellular ligand-binding receptor K01999 - - 1.74e-196 628.0
HKD3_k127_3380539_4 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 557.0
HKD3_k127_3380539_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 510.0
HKD3_k127_3380539_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 509.0
HKD3_k127_3380539_7 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 489.0
HKD3_k127_3380539_8 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 390.0
HKD3_k127_3380539_9 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 380.0
HKD3_k127_3582049_0 Recombination factor protein RarA K07478 - - 1.378e-207 656.0
HKD3_k127_3582049_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 597.0
HKD3_k127_3582049_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 390.0
HKD3_k127_3582049_3 Putative serine dehydratase domain - - - 0.00000000000000000000000000000001891 127.0
HKD3_k127_3634226_0 PQQ enzyme repeat - - - 3.634e-306 945.0
HKD3_k127_3634226_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.326e-243 759.0
HKD3_k127_3634226_10 LysM domain K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 523.0
HKD3_k127_3634226_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 485.0
HKD3_k127_3634226_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 473.0
HKD3_k127_3634226_13 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
HKD3_k127_3634226_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 360.0
HKD3_k127_3634226_15 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 342.0
HKD3_k127_3634226_16 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 334.0
HKD3_k127_3634226_17 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 306.0
HKD3_k127_3634226_18 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002345 299.0
HKD3_k127_3634226_19 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001544 250.0
HKD3_k127_3634226_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.263e-226 710.0
HKD3_k127_3634226_20 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007347 259.0
HKD3_k127_3634226_21 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000004287 224.0
HKD3_k127_3634226_22 Sporulation related domain K03749 - - 0.000000000000000000000000000000004619 139.0
HKD3_k127_3634226_23 toxin biosynthetic process K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.0000000000000001262 90.0
HKD3_k127_3634226_3 tRNA synthetases class I (E and Q), catalytic domain K01885 - 6.1.1.17 1.643e-212 669.0
HKD3_k127_3634226_4 TonB-dependent receptor K02014 - - 2.181e-203 666.0
HKD3_k127_3634226_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 591.0
HKD3_k127_3634226_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 563.0
HKD3_k127_3634226_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 547.0
HKD3_k127_3634226_8 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 561.0
HKD3_k127_3662085_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 1.09e-294 919.0
HKD3_k127_3662085_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.427e-282 897.0
HKD3_k127_3662085_10 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 306.0
HKD3_k127_3662085_11 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 321.0
HKD3_k127_3662085_12 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 307.0
HKD3_k127_3662085_13 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003105 275.0
HKD3_k127_3662085_14 YsiA-like protein, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000006423 204.0
HKD3_k127_3662085_15 histidine utilization repressor K05836 - - 0.0000000000000000000000000000000000000000000000000001302 213.0
HKD3_k127_3662085_16 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000008685 190.0
HKD3_k127_3662085_17 LysE type translocator - - - 0.000000000000000000000000000000000000000002486 165.0
HKD3_k127_3662085_18 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000147 121.0
HKD3_k127_3662085_19 HutD K09975 - - 0.0000000000000000004769 94.0
HKD3_k127_3662085_2 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 1.043e-271 853.0
HKD3_k127_3662085_20 YbaK prolyl-tRNA synthetase associated - - - 0.00000000000004211 84.0
HKD3_k127_3662085_21 - - - - 0.0000005659 60.0
HKD3_k127_3662085_3 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 607.0
HKD3_k127_3662085_4 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 507.0
HKD3_k127_3662085_5 imidazolonepropionase activity K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 502.0
HKD3_k127_3662085_6 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
HKD3_k127_3662085_7 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 423.0
HKD3_k127_3662085_8 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 392.0
HKD3_k127_3662085_9 deiminase K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 333.0
HKD3_k127_371084_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 7.142e-206 652.0
HKD3_k127_371084_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.445e-195 615.0
HKD3_k127_371084_10 PFAM RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000000000000001832 136.0
HKD3_k127_371084_11 FixH family K09926 - - 0.00000000000000000000000000000234 130.0
HKD3_k127_371084_12 - - - - 0.00000000000002366 77.0
HKD3_k127_371084_13 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.000000000002993 67.0
HKD3_k127_371084_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 520.0
HKD3_k127_371084_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 398.0
HKD3_k127_371084_4 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 364.0
HKD3_k127_371084_5 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 336.0
HKD3_k127_371084_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001139 280.0
HKD3_k127_371084_7 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000003712 213.0
HKD3_k127_371084_8 Glutathione S-transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.000000000000000000000000000000000000000000000000000000003801 222.0
HKD3_k127_371084_9 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000001278 147.0
HKD3_k127_3769241_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1266.0
HKD3_k127_3769241_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 3.81e-214 675.0
HKD3_k127_3769241_10 iron assimilation K07223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 357.0
HKD3_k127_3769241_11 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 359.0
HKD3_k127_3769241_12 PFAM inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 344.0
HKD3_k127_3769241_13 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 325.0
HKD3_k127_3769241_14 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003197 289.0
HKD3_k127_3769241_15 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001135 267.0
HKD3_k127_3769241_16 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000003178 256.0
HKD3_k127_3769241_17 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
HKD3_k127_3769241_18 Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004418 256.0
HKD3_k127_3769241_19 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000003267 249.0
HKD3_k127_3769241_2 PFAM extracellular solute-binding protein family 1 K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 598.0
HKD3_k127_3769241_20 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000008869 233.0
HKD3_k127_3769241_21 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
HKD3_k127_3769241_22 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000000000000000001844 177.0
HKD3_k127_3769241_23 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000007533 177.0
HKD3_k127_3769241_24 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000004941 173.0
HKD3_k127_3769241_25 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000003884 164.0
HKD3_k127_3769241_26 - - - - 0.000000000000000000000000000000000000000002809 162.0
HKD3_k127_3769241_27 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000000001223 172.0
HKD3_k127_3769241_28 response to abiotic stimulus - - - 0.000000000000000000000000000000001844 133.0
HKD3_k127_3769241_29 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000002128 119.0
HKD3_k127_3769241_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 532.0
HKD3_k127_3769241_30 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000009705 125.0
HKD3_k127_3769241_31 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000141 96.0
HKD3_k127_3769241_33 Hemerythrin HHE cation binding domain - - - 0.00000000000003223 81.0
HKD3_k127_3769241_34 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000004496 73.0
HKD3_k127_3769241_4 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 425.0
HKD3_k127_3769241_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 411.0
HKD3_k127_3769241_6 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 392.0
HKD3_k127_3769241_7 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 384.0
HKD3_k127_3769241_8 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 377.0
HKD3_k127_3769241_9 impB/mucB/samB family K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 373.0
HKD3_k127_3782363_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 3.711e-198 628.0
HKD3_k127_3782363_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 605.0
HKD3_k127_3782363_10 ABC transporter permease K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 358.0
HKD3_k127_3782363_11 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 329.0
HKD3_k127_3782363_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 315.0
HKD3_k127_3782363_13 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 309.0
HKD3_k127_3782363_14 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 310.0
HKD3_k127_3782363_15 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 306.0
HKD3_k127_3782363_16 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000003853 241.0
HKD3_k127_3782363_17 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000002067 227.0
HKD3_k127_3782363_18 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000002085 207.0
HKD3_k127_3782363_19 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000003558 219.0
HKD3_k127_3782363_2 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 479.0
HKD3_k127_3782363_20 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000004852 194.0
HKD3_k127_3782363_21 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000001033 164.0
HKD3_k127_3782363_22 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000001173 166.0
HKD3_k127_3782363_23 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000009992 158.0
HKD3_k127_3782363_24 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000003955 124.0
HKD3_k127_3782363_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000001296 108.0
HKD3_k127_3782363_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000006452 112.0
HKD3_k127_3782363_27 abc transporter K02065 - - 0.000000000000000000000004576 103.0
HKD3_k127_3782363_28 STAS domain K07122 - - 0.0000002257 62.0
HKD3_k127_3782363_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 458.0
HKD3_k127_3782363_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 419.0
HKD3_k127_3782363_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 415.0
HKD3_k127_3782363_6 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 433.0
HKD3_k127_3782363_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 413.0
HKD3_k127_3782363_8 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 388.0
HKD3_k127_3782363_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 366.0
HKD3_k127_3785274_0 PFAM AMP-dependent synthetase K01895 - 6.2.1.1 0.0 1081.0
HKD3_k127_3785274_1 Periplasmic binding protein - - - 9.708e-226 705.0
HKD3_k127_3785274_2 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000006652 202.0
HKD3_k127_3785274_3 branched-chain amino acid - - - 0.00000000000000000000000000000000000000002643 154.0
HKD3_k127_3789169_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 8.331e-262 813.0
HKD3_k127_3789169_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 589.0
HKD3_k127_3789169_10 - - - - 0.0000000000000000000000000000000000000001212 173.0
HKD3_k127_3789169_11 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000002953 138.0
HKD3_k127_3789169_12 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000002229 119.0
HKD3_k127_3789169_13 - - - - 0.000000000000000004418 86.0
HKD3_k127_3789169_14 - - - - 0.0000003506 60.0
HKD3_k127_3789169_15 - - - - 0.00000376 54.0
HKD3_k127_3789169_2 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 537.0
HKD3_k127_3789169_3 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 462.0
HKD3_k127_3789169_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 300.0
HKD3_k127_3789169_5 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000573 275.0
HKD3_k127_3789169_6 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002381 269.0
HKD3_k127_3789169_7 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004705 274.0
HKD3_k127_3789169_8 response to heat K03668,K09914 - - 0.00000000000000000000000000000000000000000000000000000000000000003697 235.0
HKD3_k127_3789169_9 LemA family K03744 - - 0.000000000000000000000000000000000000000000000001441 179.0
HKD3_k127_3812365_0 PFAM Phospholipid glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 3.527e-296 929.0
HKD3_k127_3812365_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.662e-236 759.0
HKD3_k127_3812365_10 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 389.0
HKD3_k127_3812365_11 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 296.0
HKD3_k127_3812365_12 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000008697 192.0
HKD3_k127_3812365_13 HupE / UreJ protein K03192 - - 0.000000000000000000000000000000000000000001498 162.0
HKD3_k127_3812365_14 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000023 164.0
HKD3_k127_3812365_15 - - - - 0.0000000000000000000000000000000000004822 152.0
HKD3_k127_3812365_16 Cyclase dehydrase - - - 0.00000000000000000000000000000000007539 147.0
HKD3_k127_3812365_17 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000001533 122.0
HKD3_k127_3812365_18 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0000000000000000000000584 102.0
HKD3_k127_3812365_19 - - - - 0.0000000000000000000001694 108.0
HKD3_k127_3812365_2 nucleoside-diphosphate sugar epimerase - - - 1.627e-199 634.0
HKD3_k127_3812365_20 ATP synthase (F/14-kDa) subunit - - - 0.000000001151 72.0
HKD3_k127_3812365_3 small subunit K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 6.829e-199 623.0
HKD3_k127_3812365_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit - - - 7.349e-197 626.0
HKD3_k127_3812365_5 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 609.0
HKD3_k127_3812365_6 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 458.0
HKD3_k127_3812365_7 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009375 451.0
HKD3_k127_3812365_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 437.0
HKD3_k127_3812365_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 441.0
HKD3_k127_3820683_0 AMP-binding enzyme K12508 - 6.2.1.34 1.445e-286 905.0
HKD3_k127_3820683_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.728e-235 752.0
HKD3_k127_3820683_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 394.0
HKD3_k127_3820683_3 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 396.0
HKD3_k127_3820683_4 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000001605 213.0
HKD3_k127_3849319_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1755.0
HKD3_k127_3849319_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 1.923e-259 818.0
HKD3_k127_3849319_10 Protein of unknown function, DUF599 - - - 0.0000000000000000000000000000000000000000000001725 177.0
HKD3_k127_3849319_11 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000001947 140.0
HKD3_k127_3849319_12 PFAM cytochrome c class I K08738 - - 0.0000000000000007912 82.0
HKD3_k127_3849319_13 epimerase K00091 - 1.1.1.219 0.000000000001004 77.0
HKD3_k127_3849319_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000533 54.0
HKD3_k127_3849319_15 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.0000001391 55.0
HKD3_k127_3849319_16 - - - - 0.0000002343 60.0
HKD3_k127_3849319_17 Opioid growth factor receptor (OGFr) conserved region - - - 0.0002138 56.0
HKD3_k127_3849319_2 penicillin-binding protein K05367 - 2.4.1.129 5.032e-221 720.0
HKD3_k127_3849319_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.389e-199 645.0
HKD3_k127_3849319_4 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 592.0
HKD3_k127_3849319_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 574.0
HKD3_k127_3849319_6 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 558.0
HKD3_k127_3849319_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 526.0
HKD3_k127_3849319_8 Transporter K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 474.0
HKD3_k127_3849319_9 - - - - 0.0000000000000000000000000000000000000000000000000000007081 202.0
HKD3_k127_385978_0 Polysaccharide biosynthesis protein - - - 3.965e-201 640.0
HKD3_k127_385978_1 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 496.0
HKD3_k127_385978_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 466.0
HKD3_k127_385978_3 Belongs to the glycosyltransferase 26 family K05946,K13660 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 390.0
HKD3_k127_3970708_0 cytochrome C K02198 - - 8.562e-263 824.0
HKD3_k127_3970708_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 3.905e-250 796.0
HKD3_k127_3970708_10 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000001492 197.0
HKD3_k127_3970708_11 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000001583 185.0
HKD3_k127_3970708_12 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000007297 165.0
HKD3_k127_3970708_13 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000002291 136.0
HKD3_k127_3970708_14 integral membrane protein - - - 0.0000000000000000000000002539 118.0
HKD3_k127_3970708_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 366.0
HKD3_k127_3970708_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 342.0
HKD3_k127_3970708_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 314.0
HKD3_k127_3970708_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002161 252.0
HKD3_k127_3970708_6 TIGRFAM periplasmic protein thiol K02199 - - 0.0000000000000000000000000000000000000000000000000000000000003614 217.0
HKD3_k127_3970708_7 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000006558 209.0
HKD3_k127_3970708_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000008375 201.0
HKD3_k127_3970708_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000007981 198.0
HKD3_k127_4031279_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 4.786e-237 738.0
HKD3_k127_4031279_1 Transport of potassium into the cell K03549 - - 1.1e-224 720.0
HKD3_k127_4031279_10 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 415.0
HKD3_k127_4031279_11 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 420.0
HKD3_k127_4031279_12 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 376.0
HKD3_k127_4031279_13 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 379.0
HKD3_k127_4031279_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 358.0
HKD3_k127_4031279_15 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 377.0
HKD3_k127_4031279_16 Hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 329.0
HKD3_k127_4031279_17 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 317.0
HKD3_k127_4031279_18 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 337.0
HKD3_k127_4031279_19 Enoyl-(Acyl carrier protein) reductase K15734 - 1.1.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000008504 257.0
HKD3_k127_4031279_2 Aldehyde dehydrogenase family K00128,K09472 - 1.2.1.3,1.2.1.99 1.083e-222 700.0
HKD3_k127_4031279_20 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000007232 213.0
HKD3_k127_4031279_21 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000004663 168.0
HKD3_k127_4031279_22 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000003986 145.0
HKD3_k127_4031279_23 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000001881 155.0
HKD3_k127_4031279_24 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000002042 135.0
HKD3_k127_4031279_25 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000216 131.0
HKD3_k127_4031279_26 Bacterial regulatory proteins, tetR family - - - 0.0000000000000003243 89.0
HKD3_k127_4031279_28 - - - - 0.000000000001725 71.0
HKD3_k127_4031279_29 Thioesterase-like superfamily - - - 0.00003046 49.0
HKD3_k127_4031279_3 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 2.561e-205 649.0
HKD3_k127_4031279_30 Poly(hydroxyalcanoate) granule associated protein - - - 0.0001663 49.0
HKD3_k127_4031279_4 Belongs to the thiolase family K00626 - 2.3.1.9 6.616e-204 640.0
HKD3_k127_4031279_5 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 2.788e-194 622.0
HKD3_k127_4031279_6 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 614.0
HKD3_k127_4031279_7 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 578.0
HKD3_k127_4031279_8 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 584.0
HKD3_k127_4031279_9 hydrolase NrgC K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 424.0
HKD3_k127_4134012_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 8.246e-268 869.0
HKD3_k127_4134012_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 2.381e-230 730.0
HKD3_k127_4134012_10 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
HKD3_k127_4134012_11 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 419.0
HKD3_k127_4134012_12 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 367.0
HKD3_k127_4134012_13 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 361.0
HKD3_k127_4134012_14 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 348.0
HKD3_k127_4134012_15 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 337.0
HKD3_k127_4134012_16 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 328.0
HKD3_k127_4134012_17 PFAM binding-protein-dependent transport systems inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 340.0
HKD3_k127_4134012_18 Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 302.0
HKD3_k127_4134012_19 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 326.0
HKD3_k127_4134012_2 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 626.0
HKD3_k127_4134012_20 PFAM binding-protein-dependent transport systems inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002723 282.0
HKD3_k127_4134012_21 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004297 269.0
HKD3_k127_4134012_22 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate K03340 - 1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000008785 264.0
HKD3_k127_4134012_23 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001041 270.0
HKD3_k127_4134012_24 regulatory protein LysR K07219 - - 0.000000000000000000000000000000000000000000000000000000000000000000003214 248.0
HKD3_k127_4134012_25 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000003561 249.0
HKD3_k127_4134012_26 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000008825 236.0
HKD3_k127_4134012_27 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000000006038 222.0
HKD3_k127_4134012_28 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000001399 210.0
HKD3_k127_4134012_29 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000006864 208.0
HKD3_k127_4134012_30 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000001743 200.0
HKD3_k127_4134012_31 Cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000001978 190.0
HKD3_k127_4134012_32 HD domain K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000001723 149.0
HKD3_k127_4134012_33 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000002252 155.0
HKD3_k127_4134012_34 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000008072 104.0
HKD3_k127_4134012_35 PGAP1-like protein - - - 0.000000000000000000000001085 113.0
HKD3_k127_4134012_36 Copper binding periplasmic protein CusF - - - 0.0000000000000000000002663 101.0
HKD3_k127_4134012_37 - - - - 0.0000000000000000000002858 98.0
HKD3_k127_4134012_4 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 568.0
HKD3_k127_4134012_5 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 561.0
HKD3_k127_4134012_6 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 559.0
HKD3_k127_4134012_7 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 530.0
HKD3_k127_4134012_8 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 460.0
HKD3_k127_4134012_9 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 473.0
HKD3_k127_416380_0 dna topoisomerase III K03169 - 5.99.1.2 0.0 1238.0
HKD3_k127_416380_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 4.734e-270 846.0
HKD3_k127_416380_10 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 473.0
HKD3_k127_416380_11 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 403.0
HKD3_k127_416380_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 361.0
HKD3_k127_416380_13 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 353.0
HKD3_k127_416380_14 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 337.0
HKD3_k127_416380_15 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 318.0
HKD3_k127_416380_16 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 304.0
HKD3_k127_416380_17 membrane protein, TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 299.0
HKD3_k127_416380_18 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
HKD3_k127_416380_19 aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002588 285.0
HKD3_k127_416380_2 BT1 family - - - 3.315e-229 724.0
HKD3_k127_416380_20 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000001511 255.0
HKD3_k127_416380_21 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000002553 176.0
HKD3_k127_416380_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000005091 154.0
HKD3_k127_416380_23 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000006015 134.0
HKD3_k127_416380_24 peptidase inhibitor activity - - - 0.00000000000000000000000000131 133.0
HKD3_k127_416380_25 cobalamin synthesis protein, P47K - GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000004907 113.0
HKD3_k127_416380_26 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000001155 56.0
HKD3_k127_416380_27 Protein of unknown function (DUF2917) - - - 0.000001831 55.0
HKD3_k127_416380_3 Histidine kinase - - - 4.454e-213 698.0
HKD3_k127_416380_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 571.0
HKD3_k127_416380_5 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 570.0
HKD3_k127_416380_6 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 589.0
HKD3_k127_416380_7 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 503.0
HKD3_k127_416380_8 Beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 497.0
HKD3_k127_416380_9 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 491.0
HKD3_k127_4213603_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1305.0
HKD3_k127_4213603_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 595.0
HKD3_k127_4213603_10 Lysine exporter protein LysE YggA K05834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 258.0
HKD3_k127_4213603_11 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000006121 250.0
HKD3_k127_4213603_12 KR domain K00034,K00046,K00059,K00216 - 1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001864 258.0
HKD3_k127_4213603_13 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000000001353 166.0
HKD3_k127_4213603_2 Acyl-CoA synthetase K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 591.0
HKD3_k127_4213603_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 527.0
HKD3_k127_4213603_4 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 403.0
HKD3_k127_4213603_5 Transcriptional regulator K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 362.0
HKD3_k127_4213603_6 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 356.0
HKD3_k127_4213603_7 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 327.0
HKD3_k127_4213603_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005625 291.0
HKD3_k127_4213603_9 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007172 260.0
HKD3_k127_428036_0 oxidoreductase K04090 - 1.2.7.8 0.0 1624.0
HKD3_k127_428036_1 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 0.0 1025.0
HKD3_k127_428036_10 Histidine kinase K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 471.0
HKD3_k127_428036_11 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 411.0
HKD3_k127_428036_12 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 404.0
HKD3_k127_428036_13 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 396.0
HKD3_k127_428036_14 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 382.0
HKD3_k127_428036_15 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 377.0
HKD3_k127_428036_16 Mg2 and Co2 transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 367.0
HKD3_k127_428036_17 Transcriptional regulatory protein, C terminal K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 347.0
HKD3_k127_428036_18 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 323.0
HKD3_k127_428036_19 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 287.0
HKD3_k127_428036_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.082e-222 702.0
HKD3_k127_428036_20 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 301.0
HKD3_k127_428036_21 Protein of unknown function (DUF560) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002644 289.0
HKD3_k127_428036_22 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002967 235.0
HKD3_k127_428036_23 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000002753 217.0
HKD3_k127_428036_24 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000008266 207.0
HKD3_k127_428036_25 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000000005489 204.0
HKD3_k127_428036_26 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000003157 148.0
HKD3_k127_428036_27 FecR protein - - - 0.00000000000000000000000000005905 136.0
HKD3_k127_428036_28 PFAM Secreted repeat of - - - 0.00000000000000000000000000308 116.0
HKD3_k127_428036_29 - - - - 0.000000000001169 75.0
HKD3_k127_428036_3 twitching motility protein K02669,K12203 - - 2.989e-198 626.0
HKD3_k127_428036_4 Type II/IV secretion system protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 595.0
HKD3_k127_428036_5 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 541.0
HKD3_k127_428036_6 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 519.0
HKD3_k127_428036_7 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 469.0
HKD3_k127_428036_8 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 471.0
HKD3_k127_428036_9 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 466.0
HKD3_k127_4308454_0 PFAM AMP-dependent synthetase and ligase - - - 1.595e-235 740.0
HKD3_k127_4308454_1 Tripartite tricarboxylate transporter TctA family K07793 - - 6.809e-218 680.0
HKD3_k127_4308454_10 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000003122 169.0
HKD3_k127_4308454_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000001345 69.0
HKD3_k127_4308454_2 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 530.0
HKD3_k127_4308454_3 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 502.0
HKD3_k127_4308454_4 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 447.0
HKD3_k127_4308454_5 receptor K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 343.0
HKD3_k127_4308454_6 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001412 262.0
HKD3_k127_4308454_7 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000167 237.0
HKD3_k127_4308454_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000009726 226.0
HKD3_k127_4308454_9 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000002236 195.0
HKD3_k127_4326754_0 RNA polymerase sigma factor RpoH K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 400.0
HKD3_k127_4326754_1 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003942 272.0
HKD3_k127_4326754_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001973 274.0
HKD3_k127_4326754_3 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000008628 260.0
HKD3_k127_4326754_4 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000002543 136.0
HKD3_k127_4326754_5 CbiX K03795 - 4.99.1.3 0.00000000000000000000000000005242 120.0
HKD3_k127_4326754_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000001837 64.0
HKD3_k127_4480454_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1218.0
HKD3_k127_4480454_1 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 572.0
HKD3_k127_4480454_2 Lytic transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 550.0
HKD3_k127_4480454_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 413.0
HKD3_k127_4480454_4 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000000000000000000006879 189.0
HKD3_k127_4480454_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000005288 72.0
HKD3_k127_4801192_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 1.218e-293 916.0
HKD3_k127_4801192_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.13e-263 839.0
HKD3_k127_4801192_10 heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 359.0
HKD3_k127_4801192_11 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 377.0
HKD3_k127_4801192_12 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 347.0
HKD3_k127_4801192_13 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 317.0
HKD3_k127_4801192_14 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 266.0
HKD3_k127_4801192_15 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008731 239.0
HKD3_k127_4801192_16 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000001393 186.0
HKD3_k127_4801192_17 Cupin domain K21700 - - 0.0000000000000000000000000000000000002041 155.0
HKD3_k127_4801192_18 Zinc-finger domain - - - 0.0000000000000000000009932 108.0
HKD3_k127_4801192_2 Putative modulator of DNA gyrase K03568 - - 3.011e-245 764.0
HKD3_k127_4801192_3 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 2.249e-212 676.0
HKD3_k127_4801192_4 Domain of Unknown Function (DUF748) - - - 6.449e-208 693.0
HKD3_k127_4801192_5 Protein of unknown function - - - 7.624e-206 689.0
HKD3_k127_4801192_6 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 593.0
HKD3_k127_4801192_7 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 577.0
HKD3_k127_4801192_8 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 533.0
HKD3_k127_4801192_9 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 487.0
HKD3_k127_4875221_0 DNA polymerase K02337 - 2.7.7.7 0.0 1353.0
HKD3_k127_4875221_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 1.957e-291 904.0
HKD3_k127_4875221_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 331.0
HKD3_k127_4875221_11 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 318.0
HKD3_k127_4875221_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002062 259.0
HKD3_k127_4875221_13 hydrolases of the HAD superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002374 238.0
HKD3_k127_4875221_14 flavodoxin nitric oxide synthase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000002957 220.0
HKD3_k127_4875221_15 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000005489 204.0
HKD3_k127_4875221_16 - K07112 - - 0.000000000000000000000000000000000000000000000000000003041 195.0
HKD3_k127_4875221_17 - - - - 0.0000000000000000000000000000000000000000000000204 183.0
HKD3_k127_4875221_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000005901 112.0
HKD3_k127_4875221_19 - - - - 0.00000004452 57.0
HKD3_k127_4875221_2 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 546.0
HKD3_k127_4875221_20 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000005439 53.0
HKD3_k127_4875221_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 444.0
HKD3_k127_4875221_4 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 417.0
HKD3_k127_4875221_5 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 425.0
HKD3_k127_4875221_6 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 353.0
HKD3_k127_4875221_7 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 355.0
HKD3_k127_4875221_8 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 353.0
HKD3_k127_4875221_9 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 321.0
HKD3_k127_4878517_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1057.0
HKD3_k127_4878517_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 8.071e-260 805.0
HKD3_k127_4878517_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 428.0
HKD3_k127_4878517_11 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 425.0
HKD3_k127_4878517_12 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 385.0
HKD3_k127_4878517_13 response regulator K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 361.0
HKD3_k127_4878517_14 histidine kinase HAMP region domain protein K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 352.0
HKD3_k127_4878517_15 4Fe-4S single cluster domain K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 331.0
HKD3_k127_4878517_16 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 303.0
HKD3_k127_4878517_17 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 290.0
HKD3_k127_4878517_18 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002557 280.0
HKD3_k127_4878517_19 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
HKD3_k127_4878517_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335,K18005 - 1.12.1.2,1.6.5.3 3.36e-242 764.0
HKD3_k127_4878517_20 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004811 267.0
HKD3_k127_4878517_21 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 252.0
HKD3_k127_4878517_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002457 261.0
HKD3_k127_4878517_23 squalene-associated FAD-dependent desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002721 264.0
HKD3_k127_4878517_24 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003417 240.0
HKD3_k127_4878517_25 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000001471 240.0
HKD3_k127_4878517_26 squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000001605 249.0
HKD3_k127_4878517_27 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000003416 209.0
HKD3_k127_4878517_28 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000001208 160.0
HKD3_k127_4878517_29 Acetyltransferase K03789,K14742 - 2.3.1.128 0.000000000000000000000000000000000007071 146.0
HKD3_k127_4878517_3 metal-dependent hydrolase with the TIM-barrel fold - - - 2.779e-240 759.0
HKD3_k127_4878517_30 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000002037 154.0
HKD3_k127_4878517_31 hydrogenase maturation protease - - - 0.00000000000000000000000000000003517 145.0
HKD3_k127_4878517_32 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000005656 102.0
HKD3_k127_4878517_33 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000823 106.0
HKD3_k127_4878517_34 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000407 87.0
HKD3_k127_4878517_35 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000007944 60.0
HKD3_k127_4878517_4 Nickel-dependent hydrogenase K00436 - 1.12.1.2 2.236e-222 709.0
HKD3_k127_4878517_5 O-acetylhomoserine K01740 - 2.5.1.49 1.403e-213 671.0
HKD3_k127_4878517_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.294e-213 671.0
HKD3_k127_4878517_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.359e-210 663.0
HKD3_k127_4878517_8 Cysteine-rich domain - - - 9.344e-204 647.0
HKD3_k127_4878517_9 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 604.0
HKD3_k127_4915491_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 512.0
HKD3_k127_4915491_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 467.0
HKD3_k127_4915491_10 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000007522 153.0
HKD3_k127_4915491_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000001331 145.0
HKD3_k127_4915491_12 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000014 117.0
HKD3_k127_4915491_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000003368 89.0
HKD3_k127_4915491_14 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000003514 76.0
HKD3_k127_4915491_15 LysE type translocator - - - 0.00000001143 59.0
HKD3_k127_4915491_2 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 389.0
HKD3_k127_4915491_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 319.0
HKD3_k127_4915491_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 291.0
HKD3_k127_4915491_5 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008128 277.0
HKD3_k127_4915491_6 PFAM Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001838 248.0
HKD3_k127_4915491_7 protein-(glutamine-N5) methyltransferase activity K16868,K18896 - 2.1.1.156,2.1.1.265 0.00000000000000000000000000000000000000000000000000000000000000000002668 243.0
HKD3_k127_4915491_8 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000004078 218.0
HKD3_k127_4915491_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000003246 228.0
HKD3_k127_4915607_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1060.0
HKD3_k127_4915607_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 3.649e-305 948.0
HKD3_k127_4915607_10 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 390.0
HKD3_k127_4915607_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 353.0
HKD3_k127_4915607_12 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 317.0
HKD3_k127_4915607_13 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 256.0
HKD3_k127_4915607_14 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001334 246.0
HKD3_k127_4915607_15 PFAM Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000006376 228.0
HKD3_k127_4915607_16 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000127 251.0
HKD3_k127_4915607_17 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000002634 238.0
HKD3_k127_4915607_18 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000000001437 211.0
HKD3_k127_4915607_19 - - - - 0.000000000000000000000000000000000000000000000000000000000002982 218.0
HKD3_k127_4915607_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.187e-223 698.0
HKD3_k127_4915607_20 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000001679 203.0
HKD3_k127_4915607_21 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000009007 188.0
HKD3_k127_4915607_22 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000001485 175.0
HKD3_k127_4915607_23 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000003175 144.0
HKD3_k127_4915607_24 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000000000000007821 140.0
HKD3_k127_4915607_25 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000001964 133.0
HKD3_k127_4915607_26 Protein of unknown function (DUF504) - - - 0.000000000000000000000000000003079 122.0
HKD3_k127_4915607_27 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000002164 132.0
HKD3_k127_4915607_28 Phosphotransferase System K11189 - - 0.0000000000000000000000000001823 119.0
HKD3_k127_4915607_29 Transcriptional regulator - - - 0.00000000000001299 86.0
HKD3_k127_4915607_3 Glutamate-cysteine ligase K01919 - 6.3.2.2 7.911e-223 700.0
HKD3_k127_4915607_30 Membrane fusogenic activity K09806 - - 0.000000000000104 76.0
HKD3_k127_4915607_4 Ammonium Transporter Family K03320 - - 5.805e-217 687.0
HKD3_k127_4915607_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 612.0
HKD3_k127_4915607_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 594.0
HKD3_k127_4915607_7 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 565.0
HKD3_k127_4915607_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 399.0
HKD3_k127_4915607_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 402.0
HKD3_k127_4917907_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1109.0
HKD3_k127_4917907_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1079.0
HKD3_k127_4917907_10 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 4.327e-232 746.0
HKD3_k127_4917907_11 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.028e-223 696.0
HKD3_k127_4917907_12 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 8.495e-219 687.0
HKD3_k127_4917907_13 DNA polymerase III K02342 - 2.7.7.7 4.009e-207 668.0
HKD3_k127_4917907_14 single-stranded-DNA-specific exonuclease RecJ K07462 - - 2.928e-200 644.0
HKD3_k127_4917907_15 Aminotransferase K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 590.0
HKD3_k127_4917907_16 Extracellular solute-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 594.0
HKD3_k127_4917907_17 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 565.0
HKD3_k127_4917907_18 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 580.0
HKD3_k127_4917907_19 Major facilitator Superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 543.0
HKD3_k127_4917907_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1058.0
HKD3_k127_4917907_20 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 531.0
HKD3_k127_4917907_21 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 528.0
HKD3_k127_4917907_22 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 527.0
HKD3_k127_4917907_23 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 516.0
HKD3_k127_4917907_24 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 488.0
HKD3_k127_4917907_25 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 476.0
HKD3_k127_4917907_26 beta' subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 428.0
HKD3_k127_4917907_27 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 427.0
HKD3_k127_4917907_28 PFAM methylamine dehydrogenase heavy subunit K13372,K15229 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.4.9.1,1.4.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 418.0
HKD3_k127_4917907_29 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 402.0
HKD3_k127_4917907_3 His Kinase A (phosphoacceptor) domain - - - 0.0 1056.0
HKD3_k127_4917907_30 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 377.0
HKD3_k127_4917907_31 permease K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 358.0
HKD3_k127_4917907_32 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 336.0
HKD3_k127_4917907_33 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 333.0
HKD3_k127_4917907_34 PFAM TatD-related deoxyribonuclease K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 312.0
HKD3_k127_4917907_35 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 296.0
HKD3_k127_4917907_36 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001647 290.0
HKD3_k127_4917907_37 Iron-sulfur cluster assembly transcription factor K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006887 269.0
HKD3_k127_4917907_38 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
HKD3_k127_4917907_39 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006264 251.0
HKD3_k127_4917907_4 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 0.0 1049.0
HKD3_k127_4917907_40 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000003803 248.0
HKD3_k127_4917907_41 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000006877 254.0
HKD3_k127_4917907_42 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004653 238.0
HKD3_k127_4917907_43 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004722 225.0
HKD3_k127_4917907_44 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000004452 220.0
HKD3_k127_4917907_45 Haem-degrading K11477 - - 0.000000000000000000000000000000000000000000000000000000000002169 224.0
HKD3_k127_4917907_46 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000109 192.0
HKD3_k127_4917907_47 - - - - 0.00000000000000000000000000000000000000000000000000001131 209.0
HKD3_k127_4917907_48 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000004592 198.0
HKD3_k127_4917907_49 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000000001603 183.0
HKD3_k127_4917907_5 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 4.041e-300 932.0
HKD3_k127_4917907_50 NlpC/P60 family K13695,K19303 - - 0.0000000000000000000000000000000000000000000000001899 188.0
HKD3_k127_4917907_51 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.000000000000000000000000000000000000000000000002893 191.0
HKD3_k127_4917907_52 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000001457 179.0
HKD3_k127_4917907_53 DinB family - - - 0.00000000000000000000000000000000000000000000449 170.0
HKD3_k127_4917907_54 DUF218 domain - - - 0.000000000000000000000000000000000000000000824 167.0
HKD3_k127_4917907_55 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000002657 177.0
HKD3_k127_4917907_56 membrane - - - 0.0000000000000000000000000000000000000209 145.0
HKD3_k127_4917907_57 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000761 163.0
HKD3_k127_4917907_58 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000000000001048 145.0
HKD3_k127_4917907_59 protein conserved in bacteria - - - 0.0000000000000000000000000000000000005259 153.0
HKD3_k127_4917907_6 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.395e-296 915.0
HKD3_k127_4917907_61 nitrogen regulatory protein P-II - - - 0.000000000000000000000000003786 121.0
HKD3_k127_4917907_62 Fe-S assembly protein IscX - - - 0.00000000000000000000000002042 119.0
HKD3_k127_4917907_63 Cytochrome c - - - 0.00000000000000000000001007 111.0
HKD3_k127_4917907_64 Methylamine utilisation protein MauE - - - 0.00000000000000000000002754 116.0
HKD3_k127_4917907_65 Major facilitator superfamily K06902 - - 0.000000000000000000008722 100.0
HKD3_k127_4917907_66 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.00000000000000000001131 91.0
HKD3_k127_4917907_67 - - - - 0.0000003478 55.0
HKD3_k127_4917907_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.412e-267 843.0
HKD3_k127_4917907_8 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.169e-258 815.0
HKD3_k127_4917907_9 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 7.624e-245 765.0
HKD3_k127_4945821_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.723e-298 918.0
HKD3_k127_4945821_1 Oxidoreductase NAD-binding domain K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 8.191e-237 737.0
HKD3_k127_4945821_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002187 278.0
HKD3_k127_4945821_3 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.00000000000000000000000000000000002544 134.0
HKD3_k127_4960592_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.257e-274 874.0
HKD3_k127_4960592_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 505.0
HKD3_k127_4960592_2 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 419.0
HKD3_k127_4960592_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 330.0
HKD3_k127_4960592_4 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 332.0
HKD3_k127_4960592_5 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 306.0
HKD3_k127_4960592_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 304.0
HKD3_k127_4960592_7 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000001916 268.0
HKD3_k127_4960592_8 cyclic nucleotide binding K10914 - - 0.00000000000000000000001391 106.0
HKD3_k127_4960592_9 CNP1-like family - - - 0.0000000000001637 82.0
HKD3_k127_5020804_0 Histidine kinase K02487,K06596 - - 0.0 1082.0
HKD3_k127_5020804_1 chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 626.0
HKD3_k127_5020804_2 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 370.0
HKD3_k127_5020804_3 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000002517 243.0
HKD3_k127_5020804_4 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000005219 216.0
HKD3_k127_5020804_5 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000000000006587 184.0
HKD3_k127_5020804_6 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000002347 184.0
HKD3_k127_5020804_7 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.00000000000000000000000000000000000000005096 159.0
HKD3_k127_5020804_8 Two component signalling adaptor domain K02659 - - 0.00000000000000000000000000000000001201 141.0
HKD3_k127_5020804_9 Rubredoxin - - - 0.00000000000000000000000000000003532 128.0
HKD3_k127_5021843_0 Dynamin family - - - 1.917e-219 700.0
HKD3_k127_5021843_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 531.0
HKD3_k127_5021843_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 317.0
HKD3_k127_5021843_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006357 250.0
HKD3_k127_5021843_12 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000003825 217.0
HKD3_k127_5021843_13 peptidase S16 K07157 - - 0.0000000000000000000000000000000000000000000000000001086 195.0
HKD3_k127_5021843_14 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000005938 191.0
HKD3_k127_5021843_15 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000005714 180.0
HKD3_k127_5021843_16 ribosomal subunit interface protein K05808 - - 0.0000000000000000000000000000000001121 138.0
HKD3_k127_5021843_17 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000001551 119.0
HKD3_k127_5021843_18 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - 0.00000000008841 75.0
HKD3_k127_5021843_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 505.0
HKD3_k127_5021843_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 417.0
HKD3_k127_5021843_4 transport system, ATPase component K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 381.0
HKD3_k127_5021843_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 383.0
HKD3_k127_5021843_6 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 384.0
HKD3_k127_5021843_7 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 366.0
HKD3_k127_5021843_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 351.0
HKD3_k127_5021843_9 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 305.0
HKD3_k127_5033800_0 Glycosyltransferase like family 2 - - - 6.333e-218 691.0
HKD3_k127_5033800_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 5.795e-212 672.0
HKD3_k127_5033800_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 478.0
HKD3_k127_5033800_11 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 447.0
HKD3_k127_5033800_12 Psort location OuterMembrane, score 9.92 K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 439.0
HKD3_k127_5033800_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 436.0
HKD3_k127_5033800_14 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 433.0
HKD3_k127_5033800_15 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 358.0
HKD3_k127_5033800_16 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 338.0
HKD3_k127_5033800_17 response regulator, receiver K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 337.0
HKD3_k127_5033800_18 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 347.0
HKD3_k127_5033800_19 Glycosyltransferase like family 2 K07011,K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 332.0
HKD3_k127_5033800_2 O-antigen ligase like membrane protein - - - 8.795e-207 653.0
HKD3_k127_5033800_20 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006499 261.0
HKD3_k127_5033800_21 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000006917 187.0
HKD3_k127_5033800_22 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000009821 162.0
HKD3_k127_5033800_23 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000008474 161.0
HKD3_k127_5033800_3 Aldehyde dehydrogenase family K00294 - 1.2.1.88 9.127e-200 635.0
HKD3_k127_5033800_4 Belongs to the thiolase family - - - 6.895e-194 633.0
HKD3_k127_5033800_5 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 600.0
HKD3_k127_5033800_6 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 569.0
HKD3_k127_5033800_7 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 537.0
HKD3_k127_5033800_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 493.0
HKD3_k127_5033800_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 476.0
HKD3_k127_5099809_0 Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions K03476 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009987,GO:0016052,GO:0016054,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019854,GO:0030145,GO:0035460,GO:0042365,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0051186,GO:0051187,GO:0052689,GO:0071704,GO:1901575 - 6.554e-199 623.0
HKD3_k127_5099809_1 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 593.0
HKD3_k127_5099809_2 ATPases associated with a variety of cellular activities K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 395.0
HKD3_k127_5099809_3 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 395.0
HKD3_k127_5099809_4 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 328.0
HKD3_k127_5099809_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 287.0
HKD3_k127_5099809_6 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007879 263.0
HKD3_k127_5099809_7 SMART regulatory protein, ArsR K03892 - - 0.000000000000000000000000000000001565 136.0
HKD3_k127_5124833_0 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 569.0
HKD3_k127_5124833_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 556.0
HKD3_k127_5124833_10 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 318.0
HKD3_k127_5124833_11 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 289.0
HKD3_k127_5124833_12 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000002779 281.0
HKD3_k127_5124833_13 nucleotidase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000009985 259.0
HKD3_k127_5124833_14 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000243 250.0
HKD3_k127_5124833_15 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000004399 222.0
HKD3_k127_5124833_16 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000001062 208.0
HKD3_k127_5124833_17 AMMECR1 - - - 0.0000000000000000000000000000000000000000000000000000000162 205.0
HKD3_k127_5124833_18 COG0575 CDP-diglyceride synthetase - - - 0.000000000000000000000000000000000000000002087 161.0
HKD3_k127_5124833_19 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000001549 158.0
HKD3_k127_5124833_2 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 521.0
HKD3_k127_5124833_20 - - - - 0.000000000000000000000000000000000000004236 156.0
HKD3_k127_5124833_21 - - - - 0.0000000000000000000116 98.0
HKD3_k127_5124833_22 Putative mono-oxygenase ydhR - - - 0.00000000000000709 84.0
HKD3_k127_5124833_23 Cytochrome oxidase assembly protein K02259 - - 0.0000000008165 72.0
HKD3_k127_5124833_3 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 479.0
HKD3_k127_5124833_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 454.0
HKD3_k127_5124833_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 445.0
HKD3_k127_5124833_6 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 404.0
HKD3_k127_5124833_7 COG0471 Di- and tricarboxylate transporters K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 387.0
HKD3_k127_5124833_8 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 385.0
HKD3_k127_5124833_9 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 353.0
HKD3_k127_5215542_0 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 392.0
HKD3_k127_5215542_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 377.0
HKD3_k127_5215542_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 362.0
HKD3_k127_5215542_3 protein required for cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 360.0
HKD3_k127_5215542_4 cytochrome C oxidase K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000001738 241.0
HKD3_k127_5215542_5 signal sequence binding - - - 0.000000000000000000000000000000000000000000000002755 184.0
HKD3_k127_5215542_6 SURF1-like protein - - - 0.000000000000000000000000000000000000000000000005234 182.0
HKD3_k127_5215542_7 Protein of unknown function (DUF2909) - - - 0.000000000000000000000002314 104.0
HKD3_k127_5215542_8 Protein of unknown function (DUF2970) - - - 0.0000005434 60.0
HKD3_k127_5224413_0 5-oxoprolinase K01469 - 3.5.2.9 0.0 1746.0
HKD3_k127_5224413_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1714.0
HKD3_k127_5224413_10 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 562.0
HKD3_k127_5224413_11 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 559.0
HKD3_k127_5224413_12 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 532.0
HKD3_k127_5224413_13 MCRA family K10254 - 4.2.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 530.0
HKD3_k127_5224413_14 Dehydrogenase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 514.0
HKD3_k127_5224413_15 Branched-chain amino acid transport system / permease component K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 502.0
HKD3_k127_5224413_16 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 509.0
HKD3_k127_5224413_17 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 511.0
HKD3_k127_5224413_18 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 495.0
HKD3_k127_5224413_19 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 482.0
HKD3_k127_5224413_2 AMP-dependent synthetase - - - 2.535e-306 989.0
HKD3_k127_5224413_20 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 484.0
HKD3_k127_5224413_21 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 480.0
HKD3_k127_5224413_22 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 462.0
HKD3_k127_5224413_23 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 423.0
HKD3_k127_5224413_24 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 362.0
HKD3_k127_5224413_25 Branched-chain amino acid ATP-binding cassette transporter K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 362.0
HKD3_k127_5224413_26 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 352.0
HKD3_k127_5224413_27 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 354.0
HKD3_k127_5224413_28 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 346.0
HKD3_k127_5224413_29 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 328.0
HKD3_k127_5224413_3 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 2.081e-303 946.0
HKD3_k127_5224413_30 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 296.0
HKD3_k127_5224413_31 ABC-type transport system involved in lysophospholipase L1 biosynthesis ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 287.0
HKD3_k127_5224413_32 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005027 302.0
HKD3_k127_5224413_33 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002491 284.0
HKD3_k127_5224413_34 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000003799 255.0
HKD3_k127_5224413_35 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003838 256.0
HKD3_k127_5224413_36 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000003255 251.0
HKD3_k127_5224413_37 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000002672 255.0
HKD3_k127_5224413_38 ATPases associated with a variety of cellular activities K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000006843 254.0
HKD3_k127_5224413_39 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006763 244.0
HKD3_k127_5224413_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.558e-254 794.0
HKD3_k127_5224413_40 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000008506 236.0
HKD3_k127_5224413_41 racemase activity, acting on amino acids and derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000006023 230.0
HKD3_k127_5224413_42 transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000001795 225.0
HKD3_k127_5224413_43 DNA polymerase III K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000007439 224.0
HKD3_k127_5224413_44 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000004221 229.0
HKD3_k127_5224413_45 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000005222 207.0
HKD3_k127_5224413_46 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000003252 191.0
HKD3_k127_5224413_47 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000004995 178.0
HKD3_k127_5224413_48 - - - - 0.0000000000000000000000000000000000000000000007754 175.0
HKD3_k127_5224413_49 PFAM Ankyrin K06867 - - 0.000000000000000000000000000000000000000006367 164.0
HKD3_k127_5224413_5 ABC-type branched-chain amino acid transport systems periplasmic component K11959 - - 1.521e-230 721.0
HKD3_k127_5224413_50 in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active K01429 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0016787,GO:0016810,GO:0016811 3.5.1.5 0.00000000000000000000000000000000000000006257 161.0
HKD3_k127_5224413_51 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000007792 163.0
HKD3_k127_5224413_52 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000007021 160.0
HKD3_k127_5224413_53 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000004789 148.0
HKD3_k127_5224413_54 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000003867 155.0
HKD3_k127_5224413_55 PilZ domain K02676 - - 0.0000000000000000000000000000000008002 146.0
HKD3_k127_5224413_56 Ferredoxin K05337 - - 0.000000000000000000000000000000001043 131.0
HKD3_k127_5224413_57 Rubrerythrin - - - 0.000000000000000000000000000000001931 148.0
HKD3_k127_5224413_58 - - - - 0.00000000000000000000000000003542 124.0
HKD3_k127_5224413_59 calcium- and calmodulin-responsive adenylate cyclase activity K01113 - 3.1.3.1 0.0000000000000000000000000005849 124.0
HKD3_k127_5224413_6 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 1.874e-229 718.0
HKD3_k127_5224413_60 GYD domain - - - 0.000000000000000000000006867 106.0
HKD3_k127_5224413_61 Belongs to the type-B carboxylesterase lipase family - - - 0.0000000001331 68.0
HKD3_k127_5224413_62 Alpha beta hydrolase - - - 0.000003414 59.0
HKD3_k127_5224413_7 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.103e-226 707.0
HKD3_k127_5224413_8 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 7.114e-195 630.0
HKD3_k127_5224413_9 Pyridoxal-phosphate dependent enzyme K01505,K05396 - 3.5.99.7,4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 566.0
HKD3_k127_5411835_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 561.0
HKD3_k127_5411835_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 568.0
HKD3_k127_5411835_2 PFAM ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 551.0
HKD3_k127_5411835_3 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 512.0
HKD3_k127_5411835_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 325.0
HKD3_k127_5411835_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 301.0
HKD3_k127_5411835_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007335 287.0
HKD3_k127_5411835_7 Belongs to the ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000005739 123.0
HKD3_k127_5411835_8 Type II/IV secretion system protein K02670 - - 0.00000000000000005561 83.0
HKD3_k127_5483345_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0 1022.0
HKD3_k127_5483345_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 5.371e-298 934.0
HKD3_k127_5483345_10 Rubredoxin - - - 0.000000000000000000000000000000009139 130.0
HKD3_k127_5483345_11 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.000000000000000000000000000000009235 135.0
HKD3_k127_5483345_12 Hydrogenase-1 expression protein HyaE K03619 - - 0.00000000000000000000000000001071 129.0
HKD3_k127_5483345_13 small subunit K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.00000000000000000000000000004715 117.0
HKD3_k127_5483345_14 Helix-turn-helix K21498 - - 0.00000000000000000000001748 112.0
HKD3_k127_5483345_15 HupF/HypC family K04653 - - 0.00000000000000000000003328 110.0
HKD3_k127_5483345_16 carbon dioxide binding K04653 - - 0.000000000000004306 85.0
HKD3_k127_5483345_2 Belongs to the HypD family K04654 - - 3.795e-198 632.0
HKD3_k127_5483345_3 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 416.0
HKD3_k127_5483345_4 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 385.0
HKD3_k127_5483345_5 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 289.0
HKD3_k127_5483345_6 PFAM HupH hydrogenase expression protein K03618 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002206 265.0
HKD3_k127_5483345_7 hydrogenase expression formation protein K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000004524 218.0
HKD3_k127_5483345_8 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000000000000000000000000000000001679 204.0
HKD3_k127_5483345_9 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.000000000000000000000000000000001635 138.0
HKD3_k127_5567565_0 methionine synthase K00548 - 2.1.1.13 0.0 1908.0
HKD3_k127_5567565_1 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1675.0
HKD3_k127_5567565_10 Fe-S oxidoreductase K21834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 392.0
HKD3_k127_5567565_11 indolepyruvate oxidoreductase subunit B K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 408.0
HKD3_k127_5567565_12 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 347.0
HKD3_k127_5567565_13 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 364.0
HKD3_k127_5567565_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 347.0
HKD3_k127_5567565_15 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 340.0
HKD3_k127_5567565_16 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 342.0
HKD3_k127_5567565_17 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 329.0
HKD3_k127_5567565_18 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 302.0
HKD3_k127_5567565_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008719 284.0
HKD3_k127_5567565_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1055.0
HKD3_k127_5567565_20 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002992 290.0
HKD3_k127_5567565_21 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004782 248.0
HKD3_k127_5567565_22 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000008511 274.0
HKD3_k127_5567565_23 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001366 261.0
HKD3_k127_5567565_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001877 248.0
HKD3_k127_5567565_25 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000002137 256.0
HKD3_k127_5567565_26 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000001962 191.0
HKD3_k127_5567565_27 DsrC like protein - - - 0.00000000000000000000000000000000000000009882 162.0
HKD3_k127_5567565_28 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000001628 159.0
HKD3_k127_5567565_29 protein, possibly involved in utilization of glycolate and propanediol K11477 - - 0.0000000000000000000000000000000000004431 147.0
HKD3_k127_5567565_3 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 5.02e-321 999.0
HKD3_k127_5567565_30 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000001042 125.0
HKD3_k127_5567565_31 diguanylate cyclase - - - 0.00000000000000000000000000000131 136.0
HKD3_k127_5567565_32 Peptidase S24-like - - - 0.0000000000000000000000000006288 124.0
HKD3_k127_5567565_33 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000000002958 115.0
HKD3_k127_5567565_34 - - - - 0.00000000000000000000006138 105.0
HKD3_k127_5567565_35 - - - - 0.000000000000000000003302 103.0
HKD3_k127_5567565_36 - - - - 0.0000000000000000003806 91.0
HKD3_k127_5567565_37 - - - - 0.00000000005372 66.0
HKD3_k127_5567565_38 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0002224 46.0
HKD3_k127_5567565_4 Aldehyde dehydrogenase family K00141 - 1.2.1.28 1.171e-202 657.0
HKD3_k127_5567565_5 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 545.0
HKD3_k127_5567565_6 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 538.0
HKD3_k127_5567565_7 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 514.0
HKD3_k127_5567565_8 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 507.0
HKD3_k127_5567565_9 4Fe-4S binding domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 436.0
HKD3_k127_5578806_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase - - - 0.0 1457.0
HKD3_k127_5578806_1 Sulfatase K01130 - 3.1.6.1 0.0 1401.0
HKD3_k127_5578806_10 Flavin-binding monooxygenase-like - - - 3.066e-221 695.0
HKD3_k127_5578806_11 COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes K11159,K21822 - 1.13.11.82 1.767e-219 696.0
HKD3_k127_5578806_12 ABC-2 family transporter protein K01992 - - 4.285e-196 616.0
HKD3_k127_5578806_13 Epoxide hydrolase N terminus K01253 - 3.3.2.9 4.814e-194 612.0
HKD3_k127_5578806_14 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 591.0
HKD3_k127_5578806_15 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 559.0
HKD3_k127_5578806_16 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 548.0
HKD3_k127_5578806_17 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 529.0
HKD3_k127_5578806_18 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 526.0
HKD3_k127_5578806_19 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 523.0
HKD3_k127_5578806_2 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 3.958e-306 957.0
HKD3_k127_5578806_20 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 546.0
HKD3_k127_5578806_21 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 483.0
HKD3_k127_5578806_22 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 473.0
HKD3_k127_5578806_23 Dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 457.0
HKD3_k127_5578806_24 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 446.0
HKD3_k127_5578806_25 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 435.0
HKD3_k127_5578806_26 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 426.0
HKD3_k127_5578806_27 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 428.0
HKD3_k127_5578806_28 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 415.0
HKD3_k127_5578806_29 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 419.0
HKD3_k127_5578806_3 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.754e-303 972.0
HKD3_k127_5578806_30 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 415.0
HKD3_k127_5578806_31 Fasciclin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 405.0
HKD3_k127_5578806_32 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 406.0
HKD3_k127_5578806_33 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 393.0
HKD3_k127_5578806_34 secretion protein HlyD family K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 396.0
HKD3_k127_5578806_35 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 374.0
HKD3_k127_5578806_36 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 360.0
HKD3_k127_5578806_37 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 314.0
HKD3_k127_5578806_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 306.0
HKD3_k127_5578806_39 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 311.0
HKD3_k127_5578806_4 AMP-binding enzyme C-terminal domain K00666 - - 1.848e-282 883.0
HKD3_k127_5578806_40 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 309.0
HKD3_k127_5578806_41 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 291.0
HKD3_k127_5578806_42 hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000029 265.0
HKD3_k127_5578806_43 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009396 261.0
HKD3_k127_5578806_44 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001218 250.0
HKD3_k127_5578806_45 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002359 247.0
HKD3_k127_5578806_46 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000427 253.0
HKD3_k127_5578806_47 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000001335 241.0
HKD3_k127_5578806_48 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003137 228.0
HKD3_k127_5578806_49 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001111 224.0
HKD3_k127_5578806_5 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.483e-267 850.0
HKD3_k127_5578806_50 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000134 231.0
HKD3_k127_5578806_51 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000003246 205.0
HKD3_k127_5578806_52 - - - - 0.0000000000000000000000000000000000000000000000001793 190.0
HKD3_k127_5578806_53 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000006886 198.0
HKD3_k127_5578806_54 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000001811 179.0
HKD3_k127_5578806_55 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000002274 168.0
HKD3_k127_5578806_56 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000004798 188.0
HKD3_k127_5578806_58 Outer Membrane Lipoprotein K06077 - - 0.00000000000000000000000000000000000002319 149.0
HKD3_k127_5578806_59 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000002096 162.0
HKD3_k127_5578806_6 ABC transporter transmembrane region K06147,K18893 - - 4.298e-243 766.0
HKD3_k127_5578806_60 - - - - 0.00000000000000000000000000000000001718 147.0
HKD3_k127_5578806_61 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000003363 138.0
HKD3_k127_5578806_62 - - - - 0.000000000000000000000000000003379 131.0
HKD3_k127_5578806_63 Cupin 2, conserved barrel domain protein K21700 - - 0.0000000000000000000000000002138 120.0
HKD3_k127_5578806_64 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000003906 119.0
HKD3_k127_5578806_65 oxidation-reduction process - - - 0.000000000000000000000001607 113.0
HKD3_k127_5578806_66 - - - - 0.00000000000000000000000252 109.0
HKD3_k127_5578806_68 acetyltransferase - - - 0.00000000000000001128 93.0
HKD3_k127_5578806_69 Putative prokaryotic signal transducing protein - - - 0.00000000000000153 83.0
HKD3_k127_5578806_7 Protein of unknown function (DUF1254) - - - 7.587e-239 746.0
HKD3_k127_5578806_70 Ion channel - - - 0.0000000000000658 81.0
HKD3_k127_5578806_71 - - - - 0.0000000000001741 78.0
HKD3_k127_5578806_72 Transcriptional regulatory protein, C terminal - - - 0.000000000003714 67.0
HKD3_k127_5578806_73 - - - - 0.0001854 49.0
HKD3_k127_5578806_8 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 1.026e-231 729.0
HKD3_k127_5578806_9 Cytochrome c554 and c-prime - - - 1.387e-231 742.0
HKD3_k127_5667924_0 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 544.0
HKD3_k127_5667924_1 alcohol dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 532.0
HKD3_k127_5667924_2 Von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 349.0
HKD3_k127_5667924_3 - - - - 0.000000000000000000000000001291 113.0
HKD3_k127_5667924_5 HupE / UreJ protein - - - 0.0000008636 54.0
HKD3_k127_579563_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.839e-214 670.0
HKD3_k127_579563_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.628e-208 669.0
HKD3_k127_579563_10 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 376.0
HKD3_k127_579563_11 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 352.0
HKD3_k127_579563_12 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 322.0
HKD3_k127_579563_13 lipid A biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 307.0
HKD3_k127_579563_14 PFAM regulatory protein TetR K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003555 276.0
HKD3_k127_579563_15 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000004635 271.0
HKD3_k127_579563_16 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001969 263.0
HKD3_k127_579563_17 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000001349 252.0
HKD3_k127_579563_18 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000001831 246.0
HKD3_k127_579563_19 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000007597 237.0
HKD3_k127_579563_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 640.0
HKD3_k127_579563_20 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000001751 222.0
HKD3_k127_579563_21 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000267 209.0
HKD3_k127_579563_22 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000001272 204.0
HKD3_k127_579563_23 Competence protein - - - 0.0000000000000000000000000000000000000000000228 173.0
HKD3_k127_579563_24 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000003126 172.0
HKD3_k127_579563_25 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000003009 139.0
HKD3_k127_579563_26 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000003184 140.0
HKD3_k127_579563_27 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000001947 140.0
HKD3_k127_579563_28 Bacterial SH3 domain - - - 0.00000000000000000000000000000000028 140.0
HKD3_k127_579563_29 Integral membrane protein (DUF2244) - - - 0.00000000000000000000000000003442 123.0
HKD3_k127_579563_3 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 605.0
HKD3_k127_579563_30 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000004159 117.0
HKD3_k127_579563_31 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000006091 112.0
HKD3_k127_579563_32 Belongs to the Fur family K03711 - - 0.00000000000000000000007824 115.0
HKD3_k127_579563_33 GtrA-like protein - - - 0.0000006704 57.0
HKD3_k127_579563_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 522.0
HKD3_k127_579563_5 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 504.0
HKD3_k127_579563_6 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 486.0
HKD3_k127_579563_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 460.0
HKD3_k127_579563_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 425.0
HKD3_k127_579563_9 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 398.0
HKD3_k127_5883349_0 helicase superfamily c-terminal domain K03724 - - 0.0 1072.0
HKD3_k127_5883349_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1002.0
HKD3_k127_5883349_10 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 383.0
HKD3_k127_5883349_11 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 347.0
HKD3_k127_5883349_12 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 344.0
HKD3_k127_5883349_13 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 317.0
HKD3_k127_5883349_14 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 284.0
HKD3_k127_5883349_15 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001405 284.0
HKD3_k127_5883349_16 isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002155 271.0
HKD3_k127_5883349_17 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000002018 244.0
HKD3_k127_5883349_18 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000002538 242.0
HKD3_k127_5883349_19 Branched-chain amino acid ATP-binding cassette transporter K01995,K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000995 224.0
HKD3_k127_5883349_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 5.794e-263 855.0
HKD3_k127_5883349_20 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000003011 216.0
HKD3_k127_5883349_21 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000128 209.0
HKD3_k127_5883349_22 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000002918 213.0
HKD3_k127_5883349_23 Regulatory protein, FmdB family - - - 0.000000000000000000000000001203 115.0
HKD3_k127_5883349_3 Hydantoinase B oxoprolinase K01474 - 3.5.2.14 1.216e-250 794.0
HKD3_k127_5883349_4 Belongs to the TPP enzyme family K04103 - 4.1.1.74 8.791e-232 730.0
HKD3_k127_5883349_5 Extracellular liganD-binding receptor K01999 - - 1.17e-207 655.0
HKD3_k127_5883349_6 3-isopropylmalate dehydratase large subunit K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 587.0
HKD3_k127_5883349_7 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 551.0
HKD3_k127_5883349_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 470.0
HKD3_k127_5883349_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 468.0
HKD3_k127_5969978_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 4.708e-248 785.0
HKD3_k127_5969978_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.485e-194 635.0
HKD3_k127_5969978_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 551.0
HKD3_k127_5969978_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 534.0
HKD3_k127_5969978_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 466.0
HKD3_k127_5969978_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 468.0
HKD3_k127_5969978_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 436.0
HKD3_k127_5969978_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000005039 213.0
HKD3_k127_5969978_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000002886 80.0
HKD3_k127_5969978_9 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0004583 52.0
HKD3_k127_6045703_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1272.0
HKD3_k127_6045703_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1069.0
HKD3_k127_6045703_10 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 353.0
HKD3_k127_6045703_11 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 297.0
HKD3_k127_6045703_12 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001523 289.0
HKD3_k127_6045703_13 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001429 284.0
HKD3_k127_6045703_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002026 284.0
HKD3_k127_6045703_15 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000002376 228.0
HKD3_k127_6045703_16 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000003372 207.0
HKD3_k127_6045703_17 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000004243 208.0
HKD3_k127_6045703_18 DMSO reductase anchor subunit (DmsC) K18363 - - 0.000000000000000000000000000000000000000000005101 182.0
HKD3_k127_6045703_19 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000007698 168.0
HKD3_k127_6045703_2 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 3.36e-276 871.0
HKD3_k127_6045703_20 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000211 170.0
HKD3_k127_6045703_21 Thioesterase - - - 0.000000000000000000000000000000000000000005144 163.0
HKD3_k127_6045703_22 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000002032 157.0
HKD3_k127_6045703_23 Haem-degrading - - - 0.000000000000000000000000000000000000000348 171.0
HKD3_k127_6045703_24 transcriptional regulator - - - 0.000000000000000000000000000000000000001731 152.0
HKD3_k127_6045703_25 ferredoxin - - - 0.000000000000000000000000000000009139 130.0
HKD3_k127_6045703_26 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000443 117.0
HKD3_k127_6045703_27 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000001513 106.0
HKD3_k127_6045703_28 universal stress protein - - - 0.00000000000000000001093 103.0
HKD3_k127_6045703_29 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000006172 90.0
HKD3_k127_6045703_3 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.846e-268 830.0
HKD3_k127_6045703_30 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000138 76.0
HKD3_k127_6045703_4 benzoyl-CoA reductase K04113 - 1.3.7.8 5.74e-199 624.0
HKD3_k127_6045703_5 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 587.0
HKD3_k127_6045703_6 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 595.0
HKD3_k127_6045703_7 Protein of unknown function (DUF2863) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 449.0
HKD3_k127_6045703_8 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 383.0
HKD3_k127_6045703_9 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 363.0
HKD3_k127_6076764_0 Protein of unknown function (DUF1254) - - - 9.077e-236 738.0
HKD3_k127_6076764_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.882e-214 678.0
HKD3_k127_6076764_10 PFAM MltA domain protein K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 297.0
HKD3_k127_6076764_11 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004772 297.0
HKD3_k127_6076764_12 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006566 271.0
HKD3_k127_6076764_13 Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006 244.0
HKD3_k127_6076764_14 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000006333 243.0
HKD3_k127_6076764_15 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000004638 220.0
HKD3_k127_6076764_17 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000000000000000001261 192.0
HKD3_k127_6076764_18 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000000000000000000000000000281 190.0
HKD3_k127_6076764_19 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000000000000000001201 182.0
HKD3_k127_6076764_2 PFAM ATP-binding region, ATPase domain protein K07637 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 498.0
HKD3_k127_6076764_20 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000003194 123.0
HKD3_k127_6076764_21 Cold shock protein K03704 - - 0.0000000000000000000000000001517 115.0
HKD3_k127_6076764_22 Peptidase propeptide and YPEB domain - - - 0.00000000000000000000002136 103.0
HKD3_k127_6076764_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 393.0
HKD3_k127_6076764_4 Bacterial regulatory helix-turn-helix protein, lysR family K21703,K21711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 374.0
HKD3_k127_6076764_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 366.0
HKD3_k127_6076764_6 PFAM response regulator receiver K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 369.0
HKD3_k127_6076764_7 Squalene epoxidase K03184,K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 350.0
HKD3_k127_6076764_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 318.0
HKD3_k127_6076764_9 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 306.0
HKD3_k127_6085215_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.279e-240 749.0
HKD3_k127_6085215_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 501.0
HKD3_k127_6085215_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 341.0
HKD3_k127_6085215_3 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000000000000000332 192.0
HKD3_k127_6085215_4 - - - - 0.000000000000000000000000000000000000003415 166.0
HKD3_k127_6085215_5 Cas6 Crispr - - - 0.0000000000000000000000000000000000003598 150.0
HKD3_k127_6085215_6 - - - - 0.0000000000000158 87.0
HKD3_k127_6103446_0 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 509.0
HKD3_k127_6103446_1 Alpha/beta hydrolase of unknown function (DUF1100) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 352.0
HKD3_k127_6103446_10 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000001528 151.0
HKD3_k127_6103446_11 Cupin domain - - - 0.00000000000000000000000000000000002154 152.0
HKD3_k127_6103446_12 Transposase K07481 - - 0.0000000000000000000000000000484 117.0
HKD3_k127_6103446_13 DDE superfamily endonuclease - - - 0.000000000000000000008631 93.0
HKD3_k127_6103446_14 DoxX - - - 0.0000000000000001502 85.0
HKD3_k127_6103446_15 transposition, DNA-mediated - - - 0.00000000009769 66.0
HKD3_k127_6103446_16 transcriptional regulator - - - 0.0000006352 61.0
HKD3_k127_6103446_17 Transposase zinc-ribbon domain - - - 0.00001145 50.0
HKD3_k127_6103446_18 DDE superfamily endonuclease - - - 0.00003317 47.0
HKD3_k127_6103446_19 ISXO2-like transposase domain - - - 0.0004732 49.0
HKD3_k127_6103446_2 thiolester hydrolase activity K11750 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 351.0
HKD3_k127_6103446_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 346.0
HKD3_k127_6103446_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 324.0
HKD3_k127_6103446_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001468 264.0
HKD3_k127_6103446_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000001464 240.0
HKD3_k127_6103446_7 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000000000000000000000001497 250.0
HKD3_k127_6103446_8 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000001366 205.0
HKD3_k127_6103446_9 regulatory protein TetR - - - 0.00000000000000000000000000000000000000002467 169.0
HKD3_k127_6174530_0 AcrB/AcrD/AcrF family - - - 0.0 1594.0
HKD3_k127_6174530_1 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 3.02e-321 987.0
HKD3_k127_6174530_10 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 385.0
HKD3_k127_6174530_11 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 376.0
HKD3_k127_6174530_12 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 365.0
HKD3_k127_6174530_13 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 356.0
HKD3_k127_6174530_14 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 346.0
HKD3_k127_6174530_15 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 336.0
HKD3_k127_6174530_16 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 304.0
HKD3_k127_6174530_17 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002992 275.0
HKD3_k127_6174530_18 regulatory protein Crp K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000001198 240.0
HKD3_k127_6174530_19 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000004492 177.0
HKD3_k127_6174530_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 6.448e-320 1002.0
HKD3_k127_6174530_20 Molybdopterin oxidoreductase Fe4S4 domain K00370 - 1.7.5.1 0.000000000000000000000000000004786 119.0
HKD3_k127_6174530_21 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000004161 127.0
HKD3_k127_6174530_22 Protein of unknown function (DUF2892) - - - 0.0000000000000000000005645 97.0
HKD3_k127_6174530_23 membrane - - - 0.0000000000000001031 88.0
HKD3_k127_6174530_3 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.3e-235 746.0
HKD3_k127_6174530_4 (GMC) oxidoreductase K00108 - 1.1.99.1 1.124e-232 736.0
HKD3_k127_6174530_5 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 519.0
HKD3_k127_6174530_6 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 463.0
HKD3_k127_6174530_7 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 411.0
HKD3_k127_6174530_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 408.0
HKD3_k127_6174530_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 382.0
HKD3_k127_6179736_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1273.0
HKD3_k127_6179736_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1067.0
HKD3_k127_6179736_10 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 394.0
HKD3_k127_6179736_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 378.0
HKD3_k127_6179736_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 381.0
HKD3_k127_6179736_13 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 375.0
HKD3_k127_6179736_14 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 374.0
HKD3_k127_6179736_15 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 357.0
HKD3_k127_6179736_16 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 327.0
HKD3_k127_6179736_17 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 327.0
HKD3_k127_6179736_18 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003374 275.0
HKD3_k127_6179736_19 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009247 254.0
HKD3_k127_6179736_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.606e-279 902.0
HKD3_k127_6179736_20 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000002978 235.0
HKD3_k127_6179736_21 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000002499 215.0
HKD3_k127_6179736_22 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000006218 212.0
HKD3_k127_6179736_23 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000001773 192.0
HKD3_k127_6179736_24 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000001289 169.0
HKD3_k127_6179736_25 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000001288 123.0
HKD3_k127_6179736_26 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000009454 117.0
HKD3_k127_6179736_27 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000006594 110.0
HKD3_k127_6179736_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.19e-245 782.0
HKD3_k127_6179736_4 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 545.0
HKD3_k127_6179736_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 469.0
HKD3_k127_6179736_6 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 451.0
HKD3_k127_6179736_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 443.0
HKD3_k127_6179736_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 407.0
HKD3_k127_6179736_9 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 427.0
HKD3_k127_6189835_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1594.0
HKD3_k127_6189835_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1078.0
HKD3_k127_6189835_2 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 365.0
HKD3_k127_6189835_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 293.0
HKD3_k127_6189835_4 Ferredoxin K05337 - - 0.000000000007552 68.0
HKD3_k127_6219629_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1173.0
HKD3_k127_6219629_1 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 5.801e-211 666.0
HKD3_k127_6219629_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 315.0
HKD3_k127_6219629_11 ABC transporter transmembrane region K12536 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002024 276.0
HKD3_k127_6219629_12 lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001174 274.0
HKD3_k127_6219629_13 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000008523 257.0
HKD3_k127_6219629_14 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000001698 233.0
HKD3_k127_6219629_15 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000000000000000000000000000000000000000000001358 231.0
HKD3_k127_6219629_16 Histidine kinase - - - 0.00000000000000000000000000000000000000001542 166.0
HKD3_k127_6219629_17 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000004264 151.0
HKD3_k127_6219629_18 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000003842 138.0
HKD3_k127_6219629_19 OsmC-like protein - - - 0.00000000000000000000000000003172 125.0
HKD3_k127_6219629_2 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 550.0
HKD3_k127_6219629_20 antitoxin K07172 - - 0.0000000000000000000000000008274 114.0
HKD3_k127_6219629_21 transcriptional regulator - - - 0.0000000000000000000000005927 118.0
HKD3_k127_6219629_22 - - - - 0.00000000000000000000926 100.0
HKD3_k127_6219629_23 Glycine-zipper domain - - - 0.0000000004792 65.0
HKD3_k127_6219629_3 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022,K12537,K16300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 457.0
HKD3_k127_6219629_4 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 433.0
HKD3_k127_6219629_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 392.0
HKD3_k127_6219629_6 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 404.0
HKD3_k127_6219629_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 334.0
HKD3_k127_6219629_8 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 357.0
HKD3_k127_6219629_9 Outer membrane efflux protein K12538 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 323.0
HKD3_k127_6281999_0 Carboxyl transferase domain - - - 9.511e-304 950.0
HKD3_k127_6281999_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.435e-292 912.0
HKD3_k127_6281999_10 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 375.0
HKD3_k127_6281999_11 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 340.0
HKD3_k127_6281999_12 enoyl-CoA hydratase isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 353.0
HKD3_k127_6281999_13 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001095 264.0
HKD3_k127_6281999_14 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001152 228.0
HKD3_k127_6281999_15 HpcH/HpaI aldolase/citrate lyase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000003259 208.0
HKD3_k127_6281999_16 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000001143 206.0
HKD3_k127_6281999_17 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000186 208.0
HKD3_k127_6281999_18 Complex I intermediate-associated protein 30 (CIA30) - - - 0.00000000000000000000000000000000771 132.0
HKD3_k127_6281999_2 Biotin carboxylase C-terminal domain - - - 8.611e-285 889.0
HKD3_k127_6281999_3 NADH:flavin oxidoreductase / NADH oxidase family - - - 6.564e-207 657.0
HKD3_k127_6281999_4 Acyl-CoA dehydrogenase, C-terminal domain K04117 - - 1.156e-205 645.0
HKD3_k127_6281999_5 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA - - - 3.065e-194 638.0
HKD3_k127_6281999_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 612.0
HKD3_k127_6281999_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 461.0
HKD3_k127_6281999_8 Enoyl-CoA hydratase/isomerase K07536 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 445.0
HKD3_k127_6281999_9 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 417.0
HKD3_k127_6283956_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.153e-225 707.0
HKD3_k127_6283956_1 ABC-type spermidine putrescine transport system, ATPase component K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 432.0
HKD3_k127_6283956_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 441.0
HKD3_k127_6283956_3 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 338.0
HKD3_k127_6283956_4 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000000001752 219.0
HKD3_k127_6283956_5 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000008399 164.0
HKD3_k127_6283956_6 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000007331 99.0
HKD3_k127_6319267_0 Fumarase C C-terminus K01744 - 4.3.1.1 1.63e-271 840.0
HKD3_k127_6319267_1 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 1.206e-229 717.0
HKD3_k127_6319267_10 Member of a two-component regulatory system K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 334.0
HKD3_k127_6319267_11 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 308.0
HKD3_k127_6319267_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 322.0
HKD3_k127_6319267_13 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 302.0
HKD3_k127_6319267_14 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001017 268.0
HKD3_k127_6319267_15 DJ-1/PfpI family K18199 - 4.2.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000001255 257.0
HKD3_k127_6319267_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001667 229.0
HKD3_k127_6319267_17 Sensors of blue-light using FAD - - - 0.0000000000000000000000000000000000000000000000000000000000241 209.0
HKD3_k127_6319267_18 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000001693 218.0
HKD3_k127_6319267_19 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000002704 215.0
HKD3_k127_6319267_2 Cupin domain K00450 - 1.13.11.4 7.137e-195 610.0
HKD3_k127_6319267_20 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000001536 209.0
HKD3_k127_6319267_21 PFAM CHASE2 domain - - - 0.0000000000000000000000000000000000000000000000000000001409 219.0
HKD3_k127_6319267_22 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000006633 206.0
HKD3_k127_6319267_23 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 0.00000000000000000000000000000000000001609 145.0
HKD3_k127_6319267_24 Response regulator receiver - - - 0.00000000000000000000000000000001052 146.0
HKD3_k127_6319267_25 - - - - 0.000000000000000000000000000003287 133.0
HKD3_k127_6319267_26 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000009056 130.0
HKD3_k127_6319267_27 Bacterial SH3 domain - - - 0.0000001069 61.0
HKD3_k127_6319267_3 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 568.0
HKD3_k127_6319267_4 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 563.0
HKD3_k127_6319267_5 Aminotransferase K09758 - 4.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 550.0
HKD3_k127_6319267_6 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 422.0
HKD3_k127_6319267_7 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 386.0
HKD3_k127_6319267_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 340.0
HKD3_k127_6319267_9 phosphoglucosamine mutase activity K00344,K01840,K03431,K15778,K16881 - 1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 356.0
HKD3_k127_6320531_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 7.728e-310 968.0
HKD3_k127_6320531_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 498.0
HKD3_k127_6320531_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 285.0
HKD3_k127_6320531_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000002609 189.0
HKD3_k127_6320531_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000005531 112.0
HKD3_k127_6320531_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000005963 108.0
HKD3_k127_6365121_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.641e-227 711.0
HKD3_k127_6365121_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.856e-209 670.0
HKD3_k127_6365121_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 562.0
HKD3_k127_6365121_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 435.0
HKD3_k127_6365121_4 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 423.0
HKD3_k127_6365121_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 334.0
HKD3_k127_6365121_6 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003528 278.0
HKD3_k127_6365121_7 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001845 263.0
HKD3_k127_6365121_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009737 270.0
HKD3_k127_6525610_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 587.0
HKD3_k127_6525610_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 565.0
HKD3_k127_6525610_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 306.0
HKD3_k127_6525610_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000003486 229.0
HKD3_k127_6576890_0 Rieske [2Fe-2S] domain - - - 1.94e-211 673.0
HKD3_k127_6576890_1 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 1.771e-196 629.0
HKD3_k127_6576890_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 577.0
HKD3_k127_6576890_3 Alpha beta hydrolase K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000001222 241.0
HKD3_k127_6576890_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000001567 197.0
HKD3_k127_6576890_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000001607 154.0
HKD3_k127_6576890_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000002242 131.0
HKD3_k127_6576890_7 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000331 125.0
HKD3_k127_6576890_8 Protein of unknown function (DUF3567) - - - 0.00000000000000000000000003099 110.0
HKD3_k127_6637024_0 AMP-binding enzyme - - - 1.166e-316 980.0
HKD3_k127_6637024_1 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 580.0
HKD3_k127_6637024_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 469.0
HKD3_k127_6637024_3 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 460.0
HKD3_k127_6637024_4 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 346.0
HKD3_k127_6637024_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000001454 168.0
HKD3_k127_670744_0 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 4.221e-267 851.0
HKD3_k127_670744_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 513.0
HKD3_k127_670744_10 Domain of unknown function (DUF1992) - - - 0.00000000000000000006149 97.0
HKD3_k127_670744_2 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003583 280.0
HKD3_k127_670744_3 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001651 279.0
HKD3_k127_670744_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000007909 260.0
HKD3_k127_670744_5 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000001552 237.0
HKD3_k127_670744_6 TPM domain - - - 0.000000000000000000000000000000000000000007984 162.0
HKD3_k127_670744_7 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000000000007155 153.0
HKD3_k127_670744_8 Psort location Extracellular, score K07126 - - 0.000000000000000000000000000000000000001453 156.0
HKD3_k127_670744_9 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000004559 136.0
HKD3_k127_6728241_0 Sulfatase K01130 - 3.1.6.1 1.319e-229 722.0
HKD3_k127_6728241_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 442.0
HKD3_k127_6728241_2 helix_turn_helix, mercury resistance K08365 - - 0.00000000000000000000000000000000000000000001401 171.0
HKD3_k127_6728241_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000006749 114.0
HKD3_k127_6808202_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1049.0
HKD3_k127_6808202_1 acyl-CoA dehydrogenase - - - 1.363e-298 924.0
HKD3_k127_6808202_10 Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate K09018 GO:0003674,GO:0003824,GO:0004497,GO:0006139,GO:0006206,GO:0006208,GO:0006210,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0017144,GO:0019740,GO:0019859,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0052614,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.99.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 342.0
HKD3_k127_6808202_11 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 326.0
HKD3_k127_6808202_12 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 317.0
HKD3_k127_6808202_13 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004644 300.0
HKD3_k127_6808202_14 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008117 246.0
HKD3_k127_6808202_15 COG2755 Lysophospholipase L1 and related esterases - - - 0.000000000000000000000000000000000000000000000000000000000001087 221.0
HKD3_k127_6808202_16 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000000000000001257 179.0
HKD3_k127_6808202_17 Thioesterase superfamily protein K10806 - - 0.000000000000000000000000000000000000000001375 160.0
HKD3_k127_6808202_18 - - - - 0.000000000000000000000000003172 115.0
HKD3_k127_6808202_19 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - 0.0000000000000000000000001736 114.0
HKD3_k127_6808202_2 4-coumarate--CoA - - - 1.504e-267 854.0
HKD3_k127_6808202_3 ABC transporter transmembrane region K06147 - - 1.4e-251 790.0
HKD3_k127_6808202_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.754e-194 612.0
HKD3_k127_6808202_5 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 645.0
HKD3_k127_6808202_6 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 534.0
HKD3_k127_6808202_7 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 533.0
HKD3_k127_6808202_8 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 476.0
HKD3_k127_6808202_9 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 340.0
HKD3_k127_686339_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1499.0
HKD3_k127_686339_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1048.0
HKD3_k127_686339_10 Nudix hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000000000000000075 252.0
HKD3_k127_686339_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000204 225.0
HKD3_k127_686339_12 Catalyzes the cleavage of L-fuculose 1-phosphate to glycerone phosphate and L-lactaldehyde K01628,K22130 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008270,GO:0008738,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0043167,GO:0043169,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046372,GO:0046872,GO:0046914,GO:0071704,GO:1901575 4.1.1.104,4.1.2.17 0.000000000000000000000000000000000000000000000000000000000006116 215.0
HKD3_k127_686339_13 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000004612 188.0
HKD3_k127_686339_14 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000003614 172.0
HKD3_k127_686339_15 Regulatory protein, FmdB family - - - 0.00000000000000000000000000003355 123.0
HKD3_k127_686339_16 CcdB protein K19163 - - 0.000000000000000000000000009132 117.0
HKD3_k127_686339_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000006304 89.0
HKD3_k127_686339_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 511.0
HKD3_k127_686339_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 433.0
HKD3_k127_686339_4 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 430.0
HKD3_k127_686339_5 cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 441.0
HKD3_k127_686339_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 381.0
HKD3_k127_686339_7 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 324.0
HKD3_k127_686339_8 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003743 276.0
HKD3_k127_686339_9 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007605 269.0
HKD3_k127_6873520_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1170.0
HKD3_k127_6873520_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.488e-273 863.0
HKD3_k127_6873520_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 303.0
HKD3_k127_6873520_11 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002791 268.0
HKD3_k127_6873520_12 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000005121 231.0
HKD3_k127_6873520_13 Molybdopterin guanine dinucleotide synthesis protein B K03753 - - 0.00000000000000000000000000000000000000000000000000000000000001305 232.0
HKD3_k127_6873520_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000003303 198.0
HKD3_k127_6873520_15 nitroreductase - - - 0.0000000000000000000000000000000000000000000000001219 187.0
HKD3_k127_6873520_16 methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000001509 187.0
HKD3_k127_6873520_17 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000000002101 170.0
HKD3_k127_6873520_18 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000004465 158.0
HKD3_k127_6873520_19 PFAM cytoplasmic chaperone TorD family protein - - - 0.0000000000000000000000000000000000402 143.0
HKD3_k127_6873520_2 Belongs to the GPAT DAPAT family K00631 GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 8.684e-201 655.0
HKD3_k127_6873520_20 7TMR-DISM extracellular 2 - - - 0.00000000000000000000000000000000006502 153.0
HKD3_k127_6873520_21 CbiX K03795 - 4.99.1.3 0.000000000000000000000000001232 116.0
HKD3_k127_6873520_22 Thioredoxin domain - - - 0.000000000000000000001211 96.0
HKD3_k127_6873520_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 537.0
HKD3_k127_6873520_4 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 490.0
HKD3_k127_6873520_5 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 470.0
HKD3_k127_6873520_6 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 447.0
HKD3_k127_6873520_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 427.0
HKD3_k127_6873520_8 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 398.0
HKD3_k127_6873520_9 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 338.0
HKD3_k127_69388_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.366e-244 771.0
HKD3_k127_69388_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 521.0
HKD3_k127_69388_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 482.0
HKD3_k127_69388_3 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 477.0
HKD3_k127_69388_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 398.0
HKD3_k127_69388_5 PFAM surface antigen (D15) K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 396.0
HKD3_k127_69388_6 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 385.0
HKD3_k127_69388_7 Major facilitator superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 302.0
HKD3_k127_69388_8 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000003207 170.0
HKD3_k127_6981012_0 4Fe-4S dicluster domain - - - 3.257e-310 973.0
HKD3_k127_6981012_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.09e-266 829.0
HKD3_k127_6981012_10 Iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 361.0
HKD3_k127_6981012_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 329.0
HKD3_k127_6981012_12 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 303.0
HKD3_k127_6981012_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001064 280.0
HKD3_k127_6981012_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000003019 247.0
HKD3_k127_6981012_15 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000001431 231.0
HKD3_k127_6981012_16 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000003435 167.0
HKD3_k127_6981012_17 universal stress protein - - - 0.000000000000000000000000000000000022 140.0
HKD3_k127_6981012_18 PFAM VanZ family protein - - - 0.0000000000000000006157 102.0
HKD3_k127_6981012_2 Ammonium Transporter Family K03320,K06580 - - 9.411e-203 640.0
HKD3_k127_6981012_3 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 620.0
HKD3_k127_6981012_4 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 595.0
HKD3_k127_6981012_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 510.0
HKD3_k127_6981012_6 PFAM aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 475.0
HKD3_k127_6981012_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 421.0
HKD3_k127_6981012_8 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 396.0
HKD3_k127_6981012_9 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 383.0
HKD3_k127_7044322_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 6.405e-310 966.0
HKD3_k127_7044322_1 PFAM Glycoside hydrolase 15-related - - - 4.171e-223 716.0
HKD3_k127_7044322_10 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 342.0
HKD3_k127_7044322_11 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 322.0
HKD3_k127_7044322_12 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 340.0
HKD3_k127_7044322_13 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000133 295.0
HKD3_k127_7044322_14 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005912 274.0
HKD3_k127_7044322_15 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001935 259.0
HKD3_k127_7044322_16 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000000001318 231.0
HKD3_k127_7044322_17 Branched-chain amino acid transport system / permease component K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000003437 243.0
HKD3_k127_7044322_18 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000995 224.0
HKD3_k127_7044322_19 abc transporter, ATP-binding protein K01996,K11963 - - 0.000000000000000000000000000000000000000000000000000000000967 210.0
HKD3_k127_7044322_2 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 522.0
HKD3_k127_7044322_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000001142 203.0
HKD3_k127_7044322_21 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000001909 190.0
HKD3_k127_7044322_22 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000001293 198.0
HKD3_k127_7044322_23 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000000000000000884 173.0
HKD3_k127_7044322_24 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000001083 156.0
HKD3_k127_7044322_25 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000009107 171.0
HKD3_k127_7044322_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000002162 124.0
HKD3_k127_7044322_27 ubiquinone biosynthetic process from chorismate K03690 GO:0006082,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0019752,GO:0032150,GO:0042180,GO:0042181,GO:0043436,GO:0043648,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046417,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000006777 119.0
HKD3_k127_7044322_28 Thioesterase superfamily - - - 0.0000000000000000000000003329 111.0
HKD3_k127_7044322_29 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000002577 114.0
HKD3_k127_7044322_3 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 494.0
HKD3_k127_7044322_30 Protein of unknown function (DUF2490) - - - 0.000000000000001341 86.0
HKD3_k127_7044322_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 476.0
HKD3_k127_7044322_5 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 406.0
HKD3_k127_7044322_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 390.0
HKD3_k127_7044322_7 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 387.0
HKD3_k127_7044322_8 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 373.0
HKD3_k127_7044322_9 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 352.0
HKD3_k127_7075083_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 5.321e-291 930.0
HKD3_k127_7075083_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 7.054e-242 751.0
HKD3_k127_7075083_10 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 401.0
HKD3_k127_7075083_11 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 377.0
HKD3_k127_7075083_12 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 359.0
HKD3_k127_7075083_13 abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 347.0
HKD3_k127_7075083_14 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 319.0
HKD3_k127_7075083_15 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002785 276.0
HKD3_k127_7075083_16 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000001141 243.0
HKD3_k127_7075083_17 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000003525 242.0
HKD3_k127_7075083_18 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000003507 230.0
HKD3_k127_7075083_19 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000000193 176.0
HKD3_k127_7075083_2 abc-type branched-chain amino acid transport K01999 - - 1.796e-224 703.0
HKD3_k127_7075083_20 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000006081 140.0
HKD3_k127_7075083_21 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000004672 124.0
HKD3_k127_7075083_3 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 9.812e-218 683.0
HKD3_k127_7075083_4 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 522.0
HKD3_k127_7075083_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 522.0
HKD3_k127_7075083_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 462.0
HKD3_k127_7075083_7 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 447.0
HKD3_k127_7075083_8 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 406.0
HKD3_k127_7075083_9 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 402.0
HKD3_k127_70809_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 1941.0
HKD3_k127_70809_1 PFAM Major facilitator superfamily K02575 - - 3.35e-229 729.0
HKD3_k127_70809_2 histidine kinase, dimerisation and phosphoacceptor region K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 580.0
HKD3_k127_70809_3 response regulator, receiver K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 296.0
HKD3_k127_70809_4 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002422 270.0
HKD3_k127_70809_5 ATP synthase I chain K02116 - - 0.00000000001801 70.0
HKD3_k127_7087289_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1463.0
HKD3_k127_7087289_1 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 612.0
HKD3_k127_7087289_2 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 538.0
HKD3_k127_7087289_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 457.0
HKD3_k127_7087289_4 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 379.0
HKD3_k127_7087289_5 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
HKD3_k127_7087289_6 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000001894 115.0
HKD3_k127_7087289_7 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000002581 106.0
HKD3_k127_7087289_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000007844 74.0
HKD3_k127_7264444_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.651e-209 662.0
HKD3_k127_7264444_1 TIGRFAM phenylacetate-CoA oxygenase reductase, PaaK subunit K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 542.0
HKD3_k127_7264444_10 Phenylacetic acid degradation K02610 - - 0.00000000000000000000000000000000000000000000000009606 178.0
HKD3_k127_7264444_11 TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.000000000000000000000000000000000000000000001516 182.0
HKD3_k127_7264444_12 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000002329 142.0
HKD3_k127_7264444_13 - - - - 0.0000000000000000000000000000000007355 139.0
HKD3_k127_7264444_14 Ca2 -binding protein (EF-Hand superfamily - - - 0.00000004258 64.0
HKD3_k127_7264444_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 493.0
HKD3_k127_7264444_3 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 454.0
HKD3_k127_7264444_4 phenylacetic acid K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 322.0
HKD3_k127_7264444_5 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 285.0
HKD3_k127_7264444_6 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003173 267.0
HKD3_k127_7264444_7 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000004114 233.0
HKD3_k127_7264444_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000002753 217.0
HKD3_k127_7264444_9 PFAM regulatory protein TetR K09017 - - 0.0000000000000000000000000000000000000000000000000001527 192.0
HKD3_k127_7264832_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1472.0
HKD3_k127_7264832_1 fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 626.0
HKD3_k127_7264832_10 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002584 304.0
HKD3_k127_7264832_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004441 278.0
HKD3_k127_7264832_12 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000002069 237.0
HKD3_k127_7264832_13 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000008661 243.0
HKD3_k127_7264832_14 peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000009511 190.0
HKD3_k127_7264832_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000009785 214.0
HKD3_k127_7264832_16 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000002932 134.0
HKD3_k127_7264832_17 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000008934 147.0
HKD3_k127_7264832_18 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000001091 100.0
HKD3_k127_7264832_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 587.0
HKD3_k127_7264832_3 Transposase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 552.0
HKD3_k127_7264832_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 530.0
HKD3_k127_7264832_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 495.0
HKD3_k127_7264832_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 435.0
HKD3_k127_7264832_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 381.0
HKD3_k127_7264832_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 387.0
HKD3_k127_7264832_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 376.0
HKD3_k127_7277507_0 FAD binding domain K05712 - 1.14.13.127 2.206e-259 810.0
HKD3_k127_7277507_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.613e-227 711.0
HKD3_k127_7277507_10 Protein of unknown function (DUF2783) - - - 0.0000000000000000001823 104.0
HKD3_k127_7277507_2 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 563.0
HKD3_k127_7277507_3 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 530.0
HKD3_k127_7277507_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 469.0
HKD3_k127_7277507_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 423.0
HKD3_k127_7277507_6 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 394.0
HKD3_k127_7277507_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 293.0
HKD3_k127_7277507_8 Phenylacetic acid degradation protein PaaY K02617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000389 249.0
HKD3_k127_7277507_9 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000005806 197.0
HKD3_k127_7281496_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1399.0
HKD3_k127_7281496_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1356.0
HKD3_k127_7281496_10 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 567.0
HKD3_k127_7281496_11 Na+/H+ antiporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 554.0
HKD3_k127_7281496_12 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 497.0
HKD3_k127_7281496_13 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 423.0
HKD3_k127_7281496_14 Domain of unknown function (DUF4040) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 389.0
HKD3_k127_7281496_15 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 380.0
HKD3_k127_7281496_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 376.0
HKD3_k127_7281496_17 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 336.0
HKD3_k127_7281496_18 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 311.0
HKD3_k127_7281496_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 315.0
HKD3_k127_7281496_2 oxidoreductase activity - - - 0.0 1078.0
HKD3_k127_7281496_20 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 304.0
HKD3_k127_7281496_21 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004768 241.0
HKD3_k127_7281496_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003221 243.0
HKD3_k127_7281496_23 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000005058 230.0
HKD3_k127_7281496_24 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000003662 218.0
HKD3_k127_7281496_25 Ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000001767 223.0
HKD3_k127_7281496_26 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000001207 209.0
HKD3_k127_7281496_27 Na+/H+ ion antiporter subunit - - - 0.00000000000000000000000000000000000000000000003318 176.0
HKD3_k127_7281496_28 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000168 139.0
HKD3_k127_7281496_29 Na+/H+ antiporter subunit K05571 - - 0.00000000000000000000000000002085 124.0
HKD3_k127_7281496_3 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 4.343e-269 839.0
HKD3_k127_7281496_30 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000002907 124.0
HKD3_k127_7281496_31 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000001877 122.0
HKD3_k127_7281496_33 Multiple resistance and pH regulation protein F K05570 - - 0.0000000000008975 77.0
HKD3_k127_7281496_34 - - - - 0.0000000006455 60.0
HKD3_k127_7281496_4 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 1.013e-264 824.0
HKD3_k127_7281496_5 alcohol dehydrogenase - - - 5.475e-203 641.0
HKD3_k127_7281496_6 Belongs to the UPF0061 (SELO) family - - - 1.909e-202 649.0
HKD3_k127_7281496_7 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 583.0
HKD3_k127_7281496_8 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 569.0
HKD3_k127_7281496_9 arginine K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 555.0
HKD3_k127_7299034_0 Flavin containing amine oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 493.0
HKD3_k127_7299034_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 485.0
HKD3_k127_7299034_10 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 340.0
HKD3_k127_7299034_11 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 301.0
HKD3_k127_7299034_12 FIST_C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 307.0
HKD3_k127_7299034_13 Alpha beta K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009244 254.0
HKD3_k127_7299034_14 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000412 251.0
HKD3_k127_7299034_15 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000001875 246.0
HKD3_k127_7299034_16 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000003113 232.0
HKD3_k127_7299034_17 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000003133 233.0
HKD3_k127_7299034_18 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000000000000000000000000000000000000008463 188.0
HKD3_k127_7299034_19 VanZ like family - - - 0.000000000000000000000000000000000000000000000000002277 203.0
HKD3_k127_7299034_2 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 482.0
HKD3_k127_7299034_20 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000001046 198.0
HKD3_k127_7299034_21 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000002 191.0
HKD3_k127_7299034_22 PFAM Secreted repeat of - - - 0.000000000000000000000000000000000000000000000008094 189.0
HKD3_k127_7299034_23 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000001134 162.0
HKD3_k127_7299034_24 Ferredoxin - - - 0.000000000000000000000000000000000000009666 168.0
HKD3_k127_7299034_25 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.00000000000000000000000000000000000004874 155.0
HKD3_k127_7299034_26 Chalcone isomerase-like - - - 0.000000000000000000000000000000000001445 158.0
HKD3_k127_7299034_27 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000003228 108.0
HKD3_k127_7299034_28 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000001645 114.0
HKD3_k127_7299034_29 - - - - 0.0000000000000000000001685 109.0
HKD3_k127_7299034_3 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 460.0
HKD3_k127_7299034_31 - - - - 0.000000001336 68.0
HKD3_k127_7299034_32 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 - 0.000000001352 61.0
HKD3_k127_7299034_33 Sporulation domain protein - - - 0.00000145 62.0
HKD3_k127_7299034_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 457.0
HKD3_k127_7299034_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 415.0
HKD3_k127_7299034_6 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 416.0
HKD3_k127_7299034_7 PFAM aminotransferase, class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 384.0
HKD3_k127_7299034_8 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 352.0
HKD3_k127_7299034_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 346.0
HKD3_k127_7314825_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1047.0
HKD3_k127_7314825_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 4.784e-294 929.0
HKD3_k127_7314825_10 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 455.0
HKD3_k127_7314825_11 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 445.0
HKD3_k127_7314825_12 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 400.0
HKD3_k127_7314825_13 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 419.0
HKD3_k127_7314825_14 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 370.0
HKD3_k127_7314825_15 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 343.0
HKD3_k127_7314825_16 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 347.0
HKD3_k127_7314825_17 Predicted metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 338.0
HKD3_k127_7314825_18 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 330.0
HKD3_k127_7314825_19 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 324.0
HKD3_k127_7314825_2 PFAM AMP-dependent synthetase and ligase K00666 - - 7.14e-281 875.0
HKD3_k127_7314825_20 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 312.0
HKD3_k127_7314825_21 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 288.0
HKD3_k127_7314825_22 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008992 286.0
HKD3_k127_7314825_23 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002046 258.0
HKD3_k127_7314825_24 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000004144 231.0
HKD3_k127_7314825_25 KR domain K07124 - - 0.000000000000000000000000000000000000000000000000000000009162 227.0
HKD3_k127_7314825_26 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000001199 194.0
HKD3_k127_7314825_27 - - - - 0.00000000000000000000000000000000000000000001898 167.0
HKD3_k127_7314825_28 lipid kinase, YegS Rv2252 BmrU family - - - 0.000000000000000000000000000000000000000001423 179.0
HKD3_k127_7314825_29 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000002688 168.0
HKD3_k127_7314825_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 4.496e-243 760.0
HKD3_k127_7314825_30 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000002321 146.0
HKD3_k127_7314825_31 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000000002 113.0
HKD3_k127_7314825_32 Belongs to the acetyltransferase family. ArgA subfamily K00619 - 2.3.1.1 0.00000000000001334 80.0
HKD3_k127_7314825_4 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 5.917e-238 749.0
HKD3_k127_7314825_5 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 2.928e-204 653.0
HKD3_k127_7314825_6 cysteine biosynthetic process from serine K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 524.0
HKD3_k127_7314825_7 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 484.0
HKD3_k127_7314825_8 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 463.0
HKD3_k127_7314825_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 447.0
HKD3_k127_7341276_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 7.965e-226 722.0
HKD3_k127_7341276_1 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 7.022e-196 615.0
HKD3_k127_7341276_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 454.0
HKD3_k127_7341276_3 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 409.0
HKD3_k127_7341276_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 384.0
HKD3_k127_7341276_5 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 332.0
HKD3_k127_7341276_6 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000006372 158.0
HKD3_k127_7341276_7 Putative regulatory protein - - - 0.00000000000000001008 88.0
HKD3_k127_7369515_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.0 1427.0
HKD3_k127_7369515_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 4.892e-277 859.0
HKD3_k127_7369515_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 383.0
HKD3_k127_7369515_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005378 285.0
HKD3_k127_7369515_12 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001762 241.0
HKD3_k127_7369515_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000009194 225.0
HKD3_k127_7369515_14 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000002188 199.0
HKD3_k127_7369515_15 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000001343 174.0
HKD3_k127_7369515_16 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000001187 177.0
HKD3_k127_7369515_17 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000003569 166.0
HKD3_k127_7369515_18 Oligoketide cyclase lipid transport protein - - - 0.0000000000000000000000000000000000000000005436 164.0
HKD3_k127_7369515_19 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000961 114.0
HKD3_k127_7369515_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.088e-246 769.0
HKD3_k127_7369515_20 Conserved hypothetical protein 698 - - - 0.00000000000000000000000002755 115.0
HKD3_k127_7369515_21 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000000001249 101.0
HKD3_k127_7369515_22 Domain of unknown function (DUF4124) - - - 0.00000000000000001297 94.0
HKD3_k127_7369515_23 - - - - 0.00000000000001228 82.0
HKD3_k127_7369515_24 Belongs to the 'phage' integrase family - - - 0.0000000000001261 74.0
HKD3_k127_7369515_25 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000005986 62.0
HKD3_k127_7369515_26 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.00000009424 62.0
HKD3_k127_7369515_3 GMC oxidoreductase K03333 - 1.1.3.6 2.072e-228 719.0
HKD3_k127_7369515_4 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 550.0
HKD3_k127_7369515_5 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 518.0
HKD3_k127_7369515_6 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 484.0
HKD3_k127_7369515_7 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 464.0
HKD3_k127_7369515_8 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 459.0
HKD3_k127_7369515_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 391.0
HKD3_k127_7454584_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 3.063e-229 726.0
HKD3_k127_7454584_1 AMP-binding enzyme - - - 3.128e-228 728.0
HKD3_k127_7454584_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 328.0
HKD3_k127_7454584_3 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0002093 49.0
HKD3_k127_7463091_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1362.0
HKD3_k127_7463091_1 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 6.454e-306 947.0
HKD3_k127_7463091_10 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 380.0
HKD3_k127_7463091_11 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 366.0
HKD3_k127_7463091_12 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 336.0
HKD3_k127_7463091_13 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000003182 252.0
HKD3_k127_7463091_14 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000003971 240.0
HKD3_k127_7463091_15 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000002282 204.0
HKD3_k127_7463091_16 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000006233 185.0
HKD3_k127_7463091_17 rhamnose metabolic process - - - 0.0000000000000000000000000006977 122.0
HKD3_k127_7463091_18 - - - - 0.00000000000002006 78.0
HKD3_k127_7463091_19 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.00000000000006001 80.0
HKD3_k127_7463091_2 type II secretion system protein E K02454,K02504,K02652 - - 1.601e-258 818.0
HKD3_k127_7463091_3 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 601.0
HKD3_k127_7463091_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 557.0
HKD3_k127_7463091_5 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 552.0
HKD3_k127_7463091_6 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 462.0
HKD3_k127_7463091_7 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 423.0
HKD3_k127_7463091_8 ATPase (AAA superfamily) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 431.0
HKD3_k127_7463091_9 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 378.0
HKD3_k127_7513265_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 7.252e-273 849.0
HKD3_k127_7513265_1 zinc protease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 387.0
HKD3_k127_7513265_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
HKD3_k127_7684384_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1701.0
HKD3_k127_7684384_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 4.052e-286 915.0
HKD3_k127_7684384_10 4Fe-4S dicluster domain K00124,K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 399.0
HKD3_k127_7684384_11 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 391.0
HKD3_k127_7684384_12 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 386.0
HKD3_k127_7684384_13 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 358.0
HKD3_k127_7684384_14 formate dehydrogenase K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 349.0
HKD3_k127_7684384_15 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 351.0
HKD3_k127_7684384_16 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 289.0
HKD3_k127_7684384_17 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000002296 240.0
HKD3_k127_7684384_18 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
HKD3_k127_7684384_19 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000006915 235.0
HKD3_k127_7684384_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.611e-230 716.0
HKD3_k127_7684384_20 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000005866 216.0
HKD3_k127_7684384_21 Chaperone protein TorD - - - 0.0000000000000000000000000000000000000000000000000001952 192.0
HKD3_k127_7684384_22 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000003235 193.0
HKD3_k127_7684384_23 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03750 - 2.10.1.1 0.0000000000000000000000000000000000003646 153.0
HKD3_k127_7684384_24 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000006352 140.0
HKD3_k127_7684384_25 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000002829 134.0
HKD3_k127_7684384_26 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000005067 120.0
HKD3_k127_7684384_27 Protein of unknown function (DUF3306) - - - 0.0000000000000000000000002169 118.0
HKD3_k127_7684384_28 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000691 118.0
HKD3_k127_7684384_29 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000002345 105.0
HKD3_k127_7684384_3 4Fe-4S dicluster domain - - - 2.331e-215 691.0
HKD3_k127_7684384_32 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000001756 53.0
HKD3_k127_7684384_33 - - - - 0.000006291 57.0
HKD3_k127_7684384_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 8.441e-211 660.0
HKD3_k127_7684384_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 587.0
HKD3_k127_7684384_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 547.0
HKD3_k127_7684384_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 420.0
HKD3_k127_7684384_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 436.0
HKD3_k127_7684384_9 signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 412.0
HKD3_k127_7726898_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 9.295e-266 833.0
HKD3_k127_7726898_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 2.243e-220 695.0
HKD3_k127_7726898_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 319.0
HKD3_k127_7726898_11 ChrR Cupin-like domain K05913 - 1.13.11.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001799 297.0
HKD3_k127_7726898_12 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000004896 175.0
HKD3_k127_7726898_13 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000001877 180.0
HKD3_k127_7726898_14 YhhN family - - - 0.00000000000000000000000000004167 126.0
HKD3_k127_7726898_2 Receptor family ligand binding region - - - 2.205e-212 666.0
HKD3_k127_7726898_3 O-methyltransferase activity - - - 6.598e-194 627.0
HKD3_k127_7726898_4 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 470.0
HKD3_k127_7726898_5 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 430.0
HKD3_k127_7726898_6 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 419.0
HKD3_k127_7726898_7 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 373.0
HKD3_k127_7726898_8 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 349.0
HKD3_k127_7726898_9 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 317.0
HKD3_k127_7756860_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.931e-315 974.0
HKD3_k127_7756860_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.374e-306 947.0
HKD3_k127_7756860_10 Cytidylate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008044 258.0
HKD3_k127_7756860_11 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00800 - 1.3.1.12,2.5.1.19 0.00000000000000000000000000000000000000000000000000000001302 210.0
HKD3_k127_7756860_12 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000006848 167.0
HKD3_k127_7756860_13 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000003926 145.0
HKD3_k127_7756860_14 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000000000001137 81.0
HKD3_k127_7756860_15 Helix-hairpin-helix motif K02237 - - 0.00000000009122 75.0
HKD3_k127_7756860_16 - - - - 0.0000000002467 74.0
HKD3_k127_7756860_2 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 2.971e-208 689.0
HKD3_k127_7756860_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 598.0
HKD3_k127_7756860_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 534.0
HKD3_k127_7756860_5 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 484.0
HKD3_k127_7756860_6 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 475.0
HKD3_k127_7756860_7 acyl-CoA transferases carnitine dehydratase K14470 - 5.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 446.0
HKD3_k127_7756860_8 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 391.0
HKD3_k127_7756860_9 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 387.0
HKD3_k127_7789571_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.463e-255 792.0
HKD3_k127_7789571_1 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 545.0
HKD3_k127_7789571_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 381.0
HKD3_k127_7789571_3 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 373.0
HKD3_k127_7789571_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 361.0
HKD3_k127_7789571_5 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000000000000000002511 183.0
HKD3_k127_7789571_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000001869 151.0
HKD3_k127_7789571_7 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000003391 102.0
HKD3_k127_7789571_8 - - - - 0.0000000001046 63.0
HKD3_k127_7831151_0 SNARE associated Golgi protein - - - 7.348e-297 927.0
HKD3_k127_7831151_1 domain protein K03320 - - 1.924e-237 755.0
HKD3_k127_7831151_2 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 464.0
HKD3_k127_7831151_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000004452 220.0
HKD3_k127_7831151_4 pyridine nucleotide-disulfide oxidoreductase family protein K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000001462 199.0
HKD3_k127_7831151_5 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000005197 166.0
HKD3_k127_7831151_6 protein conserved in bacteria K09931 - - 0.0000000000000000000000000000000215 141.0
HKD3_k127_7831151_7 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000002324 99.0
HKD3_k127_811802_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 598.0
HKD3_k127_811802_1 Amidohydrolase family K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 518.0
HKD3_k127_811802_10 PFAM transport-associated - - - 0.0000000000000000000000000000000000000007626 159.0
HKD3_k127_811802_11 Protein of unknown function (DUF1282) - - - 0.0000000000000000000000000000000000823 143.0
HKD3_k127_811802_12 MarR family - - - 0.000000000000000002567 87.0
HKD3_k127_811802_13 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00001868 49.0
HKD3_k127_811802_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 440.0
HKD3_k127_811802_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 393.0
HKD3_k127_811802_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 306.0
HKD3_k127_811802_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 300.0
HKD3_k127_811802_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009475 280.0
HKD3_k127_811802_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007271 273.0
HKD3_k127_811802_8 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002649 219.0
HKD3_k127_811802_9 K channel, inward rectifier, conserved region 2 domain protein - - - 0.0000000000000000000000000000000000000000000000006391 193.0
HKD3_k127_8321725_0 Biotin carboxylase C-terminal domain - - - 0.0 1332.0
HKD3_k127_8321725_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1120.0
HKD3_k127_8321725_10 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000006622 241.0
HKD3_k127_8321725_11 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000008556 146.0
HKD3_k127_8321725_12 Nucleotidyltransferase domain - - - 0.000000000000000000000000000001062 127.0
HKD3_k127_8321725_13 Carboxyl transferase domain - - - 0.00000000000000000000001435 119.0
HKD3_k127_8321725_14 gag-polyprotein putative aspartyl protease - - - 0.0005427 54.0
HKD3_k127_8321725_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.083e-312 968.0
HKD3_k127_8321725_3 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 520.0
HKD3_k127_8321725_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 413.0
HKD3_k127_8321725_5 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 380.0
HKD3_k127_8321725_6 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 334.0
HKD3_k127_8321725_7 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 325.0
HKD3_k127_8321725_8 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 291.0
HKD3_k127_8321725_9 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000177 289.0
HKD3_k127_8465236_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1317.0
HKD3_k127_8465236_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 493.0
HKD3_k127_8465236_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 468.0
HKD3_k127_8465236_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 329.0
HKD3_k127_8465236_4 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 302.0
HKD3_k127_8465236_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 282.0
HKD3_k127_8465236_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001251 241.0
HKD3_k127_8477930_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.307e-222 704.0
HKD3_k127_8477930_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.428e-212 666.0
HKD3_k127_8477930_10 PFAM thioesterase superfamily protein K19222 - 3.1.2.28 0.00000000000000000000000000000000000000000000001047 176.0
HKD3_k127_8477930_11 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000000001733 169.0
HKD3_k127_8477930_2 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 470.0
HKD3_k127_8477930_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 291.0
HKD3_k127_8477930_4 transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005102 246.0
HKD3_k127_8477930_5 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000003146 245.0
HKD3_k127_8477930_6 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000004323 220.0
HKD3_k127_8477930_7 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000003254 200.0
HKD3_k127_8477930_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000005222 216.0
HKD3_k127_8477930_9 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000001641 188.0
HKD3_k127_8490667_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 4.122e-256 815.0
HKD3_k127_8490667_1 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 1.191e-220 702.0
HKD3_k127_8490667_10 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 398.0
HKD3_k127_8490667_11 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 366.0
HKD3_k127_8490667_12 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 343.0
HKD3_k127_8490667_13 response regulator K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 297.0
HKD3_k127_8490667_14 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000008004 231.0
HKD3_k127_8490667_15 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000001371 231.0
HKD3_k127_8490667_16 COG1226 Kef-type K transport systems - - - 0.0000000000000000000000000000000000000000001322 166.0
HKD3_k127_8490667_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 4.966e-210 666.0
HKD3_k127_8490667_3 PFAM binding-protein-dependent transport systems inner membrane component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 533.0
HKD3_k127_8490667_4 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 524.0
HKD3_k127_8490667_5 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 499.0
HKD3_k127_8490667_6 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 495.0
HKD3_k127_8490667_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 463.0
HKD3_k127_8490667_8 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 432.0
HKD3_k127_8490667_9 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 422.0
HKD3_k127_8521512_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1264.0
HKD3_k127_8521512_1 von Willebrand factor (vWF) type A domain - - - 0.0 1094.0
HKD3_k127_8521512_10 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 550.0
HKD3_k127_8521512_11 LysR substrate binding domain K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 506.0
HKD3_k127_8521512_12 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 481.0
HKD3_k127_8521512_13 carbohydrate phosphatase activity K01086 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 482.0
HKD3_k127_8521512_14 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 481.0
HKD3_k127_8521512_15 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 471.0
HKD3_k127_8521512_16 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 461.0
HKD3_k127_8521512_17 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 392.0
HKD3_k127_8521512_18 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 370.0
HKD3_k127_8521512_19 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 359.0
HKD3_k127_8521512_2 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1073.0
HKD3_k127_8521512_20 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 336.0
HKD3_k127_8521512_21 Biopolymer transport K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 309.0
HKD3_k127_8521512_22 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 309.0
HKD3_k127_8521512_23 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002197 298.0
HKD3_k127_8521512_24 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002198 269.0
HKD3_k127_8521512_25 subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002812 267.0
HKD3_k127_8521512_26 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000008351 244.0
HKD3_k127_8521512_27 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000003731 239.0
HKD3_k127_8521512_28 Protein of unknown function (DUF1211) - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000009178 194.0
HKD3_k127_8521512_29 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000001539 183.0
HKD3_k127_8521512_3 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.139e-292 901.0
HKD3_k127_8521512_30 Biopolymer transport K03559 - - 0.000000000000000000000000000000000000000000000001441 179.0
HKD3_k127_8521512_31 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000002718 147.0
HKD3_k127_8521512_32 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000000004515 145.0
HKD3_k127_8521512_33 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000001206 143.0
HKD3_k127_8521512_34 coenzyme F420 binding K07226 - - 0.000000000000000000000000000001332 140.0
HKD3_k127_8521512_35 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000003787 121.0
HKD3_k127_8521512_36 PFAM SCP-like extracellular - - - 0.000000000000000000000000341 114.0
HKD3_k127_8521512_37 TIGRFAM TonB family protein K03832 - - 0.0000000000000000002316 101.0
HKD3_k127_8521512_4 Circularly permuted ATP-grasp type 2 - - - 2.139e-223 705.0
HKD3_k127_8521512_5 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122 - 1.17.1.9 9.555e-222 700.0
HKD3_k127_8521512_6 Aminotransferase K01845 - 5.4.3.8 5.054e-200 630.0
HKD3_k127_8521512_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 599.0
HKD3_k127_8521512_8 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 555.0
HKD3_k127_8521512_9 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 531.0
HKD3_k127_8533238_0 Catalyzes the transfer of electrons from NADH to ubiquinone K00336 - 1.6.5.3 2.595e-308 963.0
HKD3_k127_8533238_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 583.0
HKD3_k127_8533238_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 305.0
HKD3_k127_8533238_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001773 257.0
HKD3_k127_8549756_0 abc transporter K06020 - 3.6.3.25 3.161e-301 931.0
HKD3_k127_8549756_1 AMP-binding enzyme C-terminal domain K00666 - - 3.086e-246 770.0
HKD3_k127_8549756_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 557.0
HKD3_k127_8549756_11 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 523.0
HKD3_k127_8549756_12 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 509.0
HKD3_k127_8549756_13 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 496.0
HKD3_k127_8549756_14 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 494.0
HKD3_k127_8549756_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 484.0
HKD3_k127_8549756_16 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 474.0
HKD3_k127_8549756_17 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 430.0
HKD3_k127_8549756_18 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 424.0
HKD3_k127_8549756_19 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 424.0
HKD3_k127_8549756_2 Belongs to the peptidase S16 family - - - 3.229e-235 752.0
HKD3_k127_8549756_20 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 411.0
HKD3_k127_8549756_21 Protein of unknown function (DUF2855) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 402.0
HKD3_k127_8549756_22 luciferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 379.0
HKD3_k127_8549756_23 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 369.0
HKD3_k127_8549756_24 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 379.0
HKD3_k127_8549756_25 Aldo/keto reductase family - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 364.0
HKD3_k127_8549756_26 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 348.0
HKD3_k127_8549756_27 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 350.0
HKD3_k127_8549756_28 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 340.0
HKD3_k127_8549756_29 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 350.0
HKD3_k127_8549756_3 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.491e-234 746.0
HKD3_k127_8549756_30 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 295.0
HKD3_k127_8549756_31 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 292.0
HKD3_k127_8549756_32 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009231 296.0
HKD3_k127_8549756_33 Ankyrin repeats (3 copies) K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001691 301.0
HKD3_k127_8549756_34 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000319 262.0
HKD3_k127_8549756_35 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008334 276.0
HKD3_k127_8549756_36 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000008081 241.0
HKD3_k127_8549756_37 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003075 254.0
HKD3_k127_8549756_38 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000002621 226.0
HKD3_k127_8549756_39 Cupin 2, conserved barrel domain protein K11312 - - 0.00000000000000000000000000000000000000000000000000000000003156 209.0
HKD3_k127_8549756_4 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 5.261e-214 677.0
HKD3_k127_8549756_40 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000004295 207.0
HKD3_k127_8549756_41 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000000003228 154.0
HKD3_k127_8549756_42 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000001609 153.0
HKD3_k127_8549756_43 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000000000000004638 131.0
HKD3_k127_8549756_44 GYD domain - - - 0.000000000000000000000002368 107.0
HKD3_k127_8549756_45 - - - - 0.000000000000000003769 92.0
HKD3_k127_8549756_46 Universal stress protein family - - - 0.000000000005715 80.0
HKD3_k127_8549756_47 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000002141 53.0
HKD3_k127_8549756_5 Tripartite tricarboxylate transporter TctA family - - - 1.65e-211 667.0
HKD3_k127_8549756_6 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 3.923e-200 639.0
HKD3_k127_8549756_7 Belongs to the thiolase family K00626 - 2.3.1.9 1.604e-196 644.0
HKD3_k127_8549756_8 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 574.0
HKD3_k127_8549756_9 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 557.0
HKD3_k127_8553012_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1054.0
HKD3_k127_8553012_1 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 5.772e-216 682.0
HKD3_k127_8553012_10 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0000000000000000000000007683 115.0
HKD3_k127_8553012_11 - - - - 0.0000000000000000000004594 113.0
HKD3_k127_8553012_12 Domain of unknown function (DUF1840) - - - 0.00000000000000000008441 100.0
HKD3_k127_8553012_14 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000001977 67.0
HKD3_k127_8553012_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 8.914e-201 634.0
HKD3_k127_8553012_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 578.0
HKD3_k127_8553012_4 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 523.0
HKD3_k127_8553012_5 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 481.0
HKD3_k127_8553012_6 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 371.0
HKD3_k127_8553012_7 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 326.0
HKD3_k127_8553012_8 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003118 286.0
HKD3_k127_8553012_9 PIN domain - - - 0.000000000000000000000000000000000008032 141.0
HKD3_k127_8573928_0 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 497.0
HKD3_k127_8573928_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 329.0
HKD3_k127_8573928_2 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 297.0
HKD3_k127_8573928_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005513 289.0
HKD3_k127_8573928_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000004183 151.0
HKD3_k127_8573928_5 - - - - 0.000000000000000000000000000002533 136.0
HKD3_k127_8583685_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.601e-216 681.0
HKD3_k127_8583685_1 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 478.0
HKD3_k127_8583685_2 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 421.0
HKD3_k127_8583685_3 chorismate binding enzyme K01851,K02361,K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 296.0
HKD3_k127_8583685_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000006663 193.0
HKD3_k127_8583685_5 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000004889 162.0
HKD3_k127_8583685_6 alpha/beta hydrolase fold K08680 - 4.2.99.20 0.00000000000000000000000000000000002077 157.0
HKD3_k127_8588547_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 556.0
HKD3_k127_8588547_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 539.0
HKD3_k127_8588547_10 TIGRFAM protein TolA K03646 - - 0.00000000000000000000000000002049 132.0
HKD3_k127_8588547_11 Acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000009109 129.0
HKD3_k127_8588547_12 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.0000000007545 60.0
HKD3_k127_8588547_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 543.0
HKD3_k127_8588547_3 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 301.0
HKD3_k127_8588547_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
HKD3_k127_8588547_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000001871 220.0
HKD3_k127_8588547_6 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000007059 215.0
HKD3_k127_8588547_7 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000002532 204.0
HKD3_k127_8588547_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000003051 210.0
HKD3_k127_8588547_9 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000001134 135.0
HKD3_k127_8588627_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 546.0
HKD3_k127_8588627_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 545.0
HKD3_k127_8588627_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 414.0
HKD3_k127_8588627_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 383.0
HKD3_k127_8588627_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009891 267.0
HKD3_k127_8588627_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
HKD3_k127_8588627_6 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000000000651 228.0
HKD3_k127_8588627_7 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000004783 216.0
HKD3_k127_8588627_8 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000002959 115.0
HKD3_k127_8608392_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1040.0
HKD3_k127_8608392_1 Molydopterin dinucleotide binding domain - - - 7.878e-281 885.0
HKD3_k127_8608392_10 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000005353 226.0
HKD3_k127_8608392_11 2-keto-4-pentenoate hydratase K01617 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000001631 214.0
HKD3_k127_8608392_12 MOSC domain - - - 0.0000000000000000000000000000000000000000000000006585 188.0
HKD3_k127_8608392_13 Thioesterase superfamily - - - 0.000000000000000000000000000000000003818 143.0
HKD3_k127_8608392_14 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000005274 112.0
HKD3_k127_8608392_15 Bacterial-like globin K06886 - - 0.000000001357 64.0
HKD3_k127_8608392_2 Bacterial transcriptional activator domain - - - 6.725e-280 900.0
HKD3_k127_8608392_3 Bacterial extracellular solute-binding protein K02055 - - 7.116e-205 646.0
HKD3_k127_8608392_4 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 556.0
HKD3_k127_8608392_5 PFAM Patatin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 344.0
HKD3_k127_8608392_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 340.0
HKD3_k127_8608392_7 Ammonia monooxygenase K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 338.0
HKD3_k127_8608392_8 oxidoreductase activity K00218 - 1.3.1.33 0.00000000000000000000000000000000000000000000000000000000000000000005563 247.0
HKD3_k127_8608392_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000001589 222.0
HKD3_k127_8625849_0 ribonuclease, Rne Rng family K08301 - - 4.441e-227 720.0
HKD3_k127_8625849_1 DNA polymerase K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 544.0
HKD3_k127_8625849_10 PFAM Glycosyl transferase, family 25 K07270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000016 244.0
HKD3_k127_8625849_11 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000006896 212.0
HKD3_k127_8625849_12 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000001471 212.0
HKD3_k127_8625849_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000007838 197.0
HKD3_k127_8625849_14 PFAM O-Antigen - - - 0.000000000000000000000000000000000000000000000000001072 206.0
HKD3_k127_8625849_15 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000004799 183.0
HKD3_k127_8625849_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 542.0
HKD3_k127_8625849_3 epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 396.0
HKD3_k127_8625849_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 394.0
HKD3_k127_8625849_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 323.0
HKD3_k127_8625849_6 PFAM glycosyl transferase family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 312.0
HKD3_k127_8625849_7 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001833 289.0
HKD3_k127_8625849_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000224 289.0
HKD3_k127_8625849_9 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005259 258.0
HKD3_k127_8641546_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 509.0
HKD3_k127_8641546_1 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 400.0
HKD3_k127_8641546_10 SnoaL-like domain - - - 0.00000000000000000000000000000000003569 141.0
HKD3_k127_8641546_11 heptosyltransferase II K02843 - - 0.000000000000000001799 85.0
HKD3_k127_8641546_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 399.0
HKD3_k127_8641546_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 389.0
HKD3_k127_8641546_4 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 392.0
HKD3_k127_8641546_5 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000001078 282.0
HKD3_k127_8641546_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 238.0
HKD3_k127_8641546_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000004038 260.0
HKD3_k127_8641546_8 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000000000000001924 169.0
HKD3_k127_8641546_9 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000002334 168.0
HKD3_k127_8667198_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1043.0
HKD3_k127_8667198_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 415.0
HKD3_k127_8667198_10 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
HKD3_k127_8667198_11 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000003538 210.0
HKD3_k127_8667198_12 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000006669 153.0
HKD3_k127_8667198_13 Belongs to the UPF0434 family K09791 - - 0.000000000000000000003472 93.0
HKD3_k127_8667198_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 382.0
HKD3_k127_8667198_3 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 382.0
HKD3_k127_8667198_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 364.0
HKD3_k127_8667198_5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity K08683 - 1.1.1.178,1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 361.0
HKD3_k127_8667198_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 324.0
HKD3_k127_8667198_7 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001193 284.0
HKD3_k127_8667198_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
HKD3_k127_8667198_9 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007957 256.0
HKD3_k127_8671341_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.127e-296 924.0
HKD3_k127_8671341_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 515.0
HKD3_k127_8671341_10 - - - - 0.00000000000001589 76.0
HKD3_k127_8671341_11 - - - - 0.00000001123 64.0
HKD3_k127_8671341_12 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000001848 56.0
HKD3_k127_8671341_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 482.0
HKD3_k127_8671341_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 418.0
HKD3_k127_8671341_4 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 418.0
HKD3_k127_8671341_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 387.0
HKD3_k127_8671341_6 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 357.0
HKD3_k127_8671341_7 Protein of unknown function (DUF3089) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 344.0
HKD3_k127_8671341_8 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 312.0
HKD3_k127_8671341_9 Cytochrome c K08738 - - 0.00000000000000000000000000000000004762 138.0
HKD3_k127_8720432_0 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 570.0
HKD3_k127_8720432_1 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 481.0
HKD3_k127_8720432_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004761 289.0
HKD3_k127_8720432_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002241 258.0
HKD3_k127_8720432_4 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000001223 245.0
HKD3_k127_8720432_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000001145 216.0
HKD3_k127_8720432_6 acyl-CoA dehydrogenase - - - 0.00000002687 58.0
HKD3_k127_8720432_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0002177 44.0
HKD3_k127_8725752_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 4.241e-237 764.0
HKD3_k127_8725752_1 belongs to the aldehyde dehydrogenase family K00130,K00151 - 1.2.1.60,1.2.1.8 2.12e-223 712.0
HKD3_k127_8725752_10 PFAM fumarylacetoacetate (FAA) hydrolase K01826 - 5.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 369.0
HKD3_k127_8725752_11 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000248 267.0
HKD3_k127_8725752_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000004513 263.0
HKD3_k127_8725752_13 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000002055 247.0
HKD3_k127_8725752_14 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000003531 201.0
HKD3_k127_8725752_15 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000003068 201.0
HKD3_k127_8725752_16 MAPEG family - - - 0.0000000000000000000000000000000000000000000007921 181.0
HKD3_k127_8725752_17 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.00000000000000000000000000000000006703 138.0
HKD3_k127_8725752_18 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000006809 135.0
HKD3_k127_8725752_19 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000000002777 126.0
HKD3_k127_8725752_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 580.0
HKD3_k127_8725752_20 transcriptional regulator K09017 - - 0.0000000000000000001312 97.0
HKD3_k127_8725752_3 3,4-dihydroxyphenylacetate 2,3-dioxygenase K00455 - 1.13.11.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 470.0
HKD3_k127_8725752_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 441.0
HKD3_k127_8725752_5 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 426.0
HKD3_k127_8725752_6 Class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 402.0
HKD3_k127_8725752_7 4-hydroxy-tetrahydrodipicolinate synthase K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 400.0
HKD3_k127_8725752_8 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 394.0
HKD3_k127_8725752_9 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 383.0
HKD3_k127_8765218_0 Formyl transferase, C-terminal domain K19640 - - 2.266e-215 683.0
HKD3_k127_8765218_1 PFAM Basic membrane lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 583.0
HKD3_k127_8765218_2 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 517.0
HKD3_k127_8765218_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 511.0
HKD3_k127_8765218_4 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 485.0
HKD3_k127_8765218_5 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 368.0
HKD3_k127_8765218_6 Beta-lactamase K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009922 372.0
HKD3_k127_8765218_7 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 279.0
HKD3_k127_8765218_8 Cytochrome K08738 - - 0.00001302 52.0
HKD3_k127_8768877_0 Cytochrome b(N-terminal)/b6/petB - - - 2.951e-239 755.0
HKD3_k127_8768877_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 9.585e-213 676.0
HKD3_k127_8768877_10 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000001766 267.0
HKD3_k127_8768877_11 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000002264 198.0
HKD3_k127_8768877_12 Rubrerythrin - - - 0.0000000000000000000000000000000000196 145.0
HKD3_k127_8768877_13 - - - - 0.0000000000008255 72.0
HKD3_k127_8768877_2 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 6.209e-197 619.0
HKD3_k127_8768877_3 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 605.0
HKD3_k127_8768877_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 583.0
HKD3_k127_8768877_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 502.0
HKD3_k127_8768877_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 409.0
HKD3_k127_8768877_7 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 395.0
HKD3_k127_8768877_8 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 315.0
HKD3_k127_8768877_9 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 301.0
HKD3_k127_8804222_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 539.0
HKD3_k127_8804222_1 FAD binding domain K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 524.0
HKD3_k127_8804222_2 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 507.0
HKD3_k127_8804222_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 368.0
HKD3_k127_8804222_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 326.0
HKD3_k127_8804222_5 -Thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000000000000000000000000000006068 192.0
HKD3_k127_8804222_6 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000009824 160.0
HKD3_k127_8804222_7 -Thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000000000000002406 153.0
HKD3_k127_8804222_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000001973 125.0
HKD3_k127_8804222_9 - - - - 0.0000000000000000000000002084 114.0
HKD3_k127_8859157_0 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 8.099e-270 839.0
HKD3_k127_8859157_1 argininosuccinate lyase K01755 - 4.3.2.1 2.694e-237 743.0
HKD3_k127_8859157_10 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 292.0
HKD3_k127_8859157_11 PFAM HemY domain protein K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001608 283.0
HKD3_k127_8859157_12 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000004329 262.0
HKD3_k127_8859157_13 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.000000000000000000000000000000000000000000000000000000000000000003485 231.0
HKD3_k127_8859157_14 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000009883 209.0
HKD3_k127_8859157_15 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000062 104.0
HKD3_k127_8859157_16 Belongs to the P(II) protein family K04751 - - 0.000000000000117 84.0
HKD3_k127_8859157_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 7.135e-229 717.0
HKD3_k127_8859157_3 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 2.851e-220 693.0
HKD3_k127_8859157_4 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 484.0
HKD3_k127_8859157_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 497.0
HKD3_k127_8859157_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 488.0
HKD3_k127_8859157_7 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 433.0
HKD3_k127_8859157_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 387.0
HKD3_k127_8859157_9 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 355.0
HKD3_k127_8885695_0 FAD linked oxidase domain protein - - - 0.0 1397.0
HKD3_k127_8885695_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 4.686e-251 790.0
HKD3_k127_8885695_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 534.0
HKD3_k127_8885695_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 523.0
HKD3_k127_8885695_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000003959 271.0
HKD3_k127_8885695_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000001717 224.0
HKD3_k127_8903846_0 ribonuclease II K01147 - 3.1.13.1 1.941e-214 685.0
HKD3_k127_8903846_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.218e-203 646.0
HKD3_k127_8903846_10 periplasmic protein TonB K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 343.0
HKD3_k127_8903846_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 304.0
HKD3_k127_8903846_12 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008332 288.0
HKD3_k127_8903846_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006938 258.0
HKD3_k127_8903846_14 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000001867 261.0
HKD3_k127_8903846_15 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000000000000000000002957 198.0
HKD3_k127_8903846_16 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000007397 183.0
HKD3_k127_8903846_17 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000002537 162.0
HKD3_k127_8903846_18 Domain of unknown function DUF302 - - - 0.000000000000281 73.0
HKD3_k127_8903846_2 Acts as a magnesium transporter K06213 - - 5.834e-197 632.0
HKD3_k127_8903846_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 536.0
HKD3_k127_8903846_4 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 505.0
HKD3_k127_8903846_5 PFAM Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 462.0
HKD3_k127_8903846_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 419.0
HKD3_k127_8903846_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 392.0
HKD3_k127_8903846_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 378.0
HKD3_k127_8903846_9 abc transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 339.0
HKD3_k127_8981464_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 8.722e-248 779.0
HKD3_k127_8981464_1 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 311.0
HKD3_k127_8981464_10 Uncharacterised protein family UPF0102 - - - 0.0000000000000000000000005166 108.0
HKD3_k127_8981464_2 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008522 289.0
HKD3_k127_8981464_3 DNA-binding transcription factor activity K14057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001582 279.0
HKD3_k127_8981464_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001702 273.0
HKD3_k127_8981464_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004204 258.0
HKD3_k127_8981464_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000006168 243.0
HKD3_k127_8981464_7 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000164 214.0
HKD3_k127_8981464_8 PFAM sulfatase - - - 0.0000000000000000000000000000000000000000000000001173 181.0
HKD3_k127_8981464_9 Sporulation related domain - - - 0.00000000000000000000000000000006616 135.0
HKD3_k127_9014957_0 Sulfatase - - - 6.451e-246 763.0
HKD3_k127_9014957_1 Phospholipase D. Active site motifs. K06132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 548.0
HKD3_k127_9014957_10 membrane - - - 0.0000000000000000000000000000000000000000000000000000005542 201.0
HKD3_k127_9014957_11 - - - - 0.00000000000000000000000000000000000000000000000001253 205.0
HKD3_k127_9014957_12 Lipid A Biosynthesis N-terminal domain - - - 0.000000000000000000000000000000001371 132.0
HKD3_k127_9014957_13 MobA MobL family protein - - - 0.00000000000000000000000002086 123.0
HKD3_k127_9014957_14 - - - - 0.00000000000000000000000004191 115.0
HKD3_k127_9014957_15 Porin subfamily - - - 0.000000000000000000000002219 119.0
HKD3_k127_9014957_16 Lysin motif - - - 0.000000000000000000006799 94.0
HKD3_k127_9014957_17 - - - - 0.0004003 48.0
HKD3_k127_9014957_2 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009438 517.0
HKD3_k127_9014957_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 495.0
HKD3_k127_9014957_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 426.0
HKD3_k127_9014957_5 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 411.0
HKD3_k127_9014957_6 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 362.0
HKD3_k127_9014957_7 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 325.0
HKD3_k127_9014957_8 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 315.0
HKD3_k127_9014957_9 PFAM CoA-binding domain protein K09181 - - 0.0000000000000000000000000000000000000000000000000000000003492 211.0
HKD3_k127_9066543_0 Malic enzyme K00029 - 1.1.1.40 0.0 1163.0
HKD3_k127_9066543_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 528.0
HKD3_k127_9066543_2 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001733 297.0
HKD3_k127_9066543_3 Protein of unknown function (DUF2505) - - - 0.000000000000000000000000000000000000001214 156.0
HKD3_k127_9066543_4 Barstar (Barnase inhibitor) - - - 0.000000000000000000000000000000000001799 160.0
HKD3_k127_9066543_5 Guanyl-specific ribonuclease Sa K01167 - 3.1.27.3 0.0000000000000000000000000000002019 136.0
HKD3_k127_9066543_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000003664 64.0
HKD3_k127_9107343_0 AMP-binding enzyme C-terminal domain K18661 - - 6.622e-226 744.0
HKD3_k127_9107343_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.382e-207 651.0
HKD3_k127_9107343_2 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 471.0
HKD3_k127_9107343_3 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 409.0
HKD3_k127_9107343_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 385.0
HKD3_k127_9107343_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 381.0
HKD3_k127_9107343_6 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 343.0
HKD3_k127_9107343_7 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000007073 281.0
HKD3_k127_9107343_8 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008617 265.0
HKD3_k127_9107343_9 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000556 85.0
HKD3_k127_935824_0 Alkyl sulfatase C-terminal - - - 1.581e-267 841.0
HKD3_k127_935824_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 5.281e-254 792.0
HKD3_k127_935824_2 Ferrous iron transport protein B K04759 - - 1.444e-236 751.0
HKD3_k127_935824_3 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 6.425e-197 637.0
HKD3_k127_935824_4 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 514.0
HKD3_k127_935824_5 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 422.0
HKD3_k127_935824_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 417.0
HKD3_k127_935824_7 PFAM 2Fe-2S -binding K07302 - 1.3.99.16 0.00000000000000000000000000000000000000003833 156.0
HKD3_k127_935824_8 CBS domain - - - 0.00000000002294 77.0
HKD3_k127_935824_9 Protein of unknown function (DUF1298) - - - 0.00000003783 59.0
HKD3_k127_9511333_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1212.0
HKD3_k127_9511333_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.652e-320 989.0
HKD3_k127_9511333_10 sulphate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 371.0
HKD3_k127_9511333_11 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 348.0
HKD3_k127_9511333_12 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 342.0
HKD3_k127_9511333_13 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 332.0
HKD3_k127_9511333_14 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 314.0
HKD3_k127_9511333_15 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002146 292.0
HKD3_k127_9511333_16 Divalent heavy-metal cations transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004895 278.0
HKD3_k127_9511333_17 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000002072 233.0
HKD3_k127_9511333_18 EamA-like transporter family K15270 - - 0.000000000000000000000000000000000000000000000000000000000000004528 226.0
HKD3_k127_9511333_19 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000001832 213.0
HKD3_k127_9511333_2 helicase K03657 - 3.6.4.12 1.023e-316 989.0
HKD3_k127_9511333_20 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000005238 192.0
HKD3_k127_9511333_21 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000001041 181.0
HKD3_k127_9511333_22 - - - - 0.00000000000000000000000000000000000000000005381 175.0
HKD3_k127_9511333_23 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000006067 99.0
HKD3_k127_9511333_3 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K03852 - 2.3.3.15 1.525e-272 852.0
HKD3_k127_9511333_4 rieske 2fe-2s K00499 - 1.14.15.7 4.83e-204 641.0
HKD3_k127_9511333_5 Acyl-CoA dehydrogenase type 2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 599.0
HKD3_k127_9511333_6 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 524.0
HKD3_k127_9511333_7 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 438.0
HKD3_k127_9511333_8 SbmA/BacA-like family K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 400.0
HKD3_k127_9511333_9 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 391.0
HKD3_k127_955083_0 Mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 584.0
HKD3_k127_955083_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 546.0
HKD3_k127_955083_10 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000004245 196.0
HKD3_k127_955083_11 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000000005709 191.0
HKD3_k127_955083_12 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000325 191.0
HKD3_k127_955083_13 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.0000000000000000000000000000000008025 143.0
HKD3_k127_955083_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000003871 77.0
HKD3_k127_955083_2 udp-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 485.0
HKD3_k127_955083_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 431.0
HKD3_k127_955083_4 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 347.0
HKD3_k127_955083_5 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 314.0
HKD3_k127_955083_6 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 299.0
HKD3_k127_955083_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 301.0
HKD3_k127_955083_8 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
HKD3_k127_955083_9 phosphate transport system K02038 - - 0.000000000000000000000000000000000000000000000000000000000000468 211.0