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Overview

ID MAG02360
Name MMD2_bin.20
Sample SMP0059
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Rariloculales
Family Rariloculaceae
Genus FEN-1219
Species
Assembly information
Completeness (%) 96.41
Contamination (%) 3.72
GC content (%) 67.0
N50 (bp) 34,044
Genome size (bp) 4,170,472

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3687

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1007844_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 4.586e-261 812.0
MMD2_k127_1007844_1 PQQ-like domain - - - 1.042e-198 645.0
MMD2_k127_1007844_10 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000004961 114.0
MMD2_k127_1007844_11 - - - - 0.0000000000000000000000006202 110.0
MMD2_k127_1007844_12 MerR, DNA binding K13639 - - 0.00000000000000000006071 96.0
MMD2_k127_1007844_15 methyltransferase K15942 - 2.1.1.288 0.00007828 46.0
MMD2_k127_1007844_2 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 469.0
MMD2_k127_1007844_3 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 310.0
MMD2_k127_1007844_4 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000009017 222.0
MMD2_k127_1007844_5 Phenazine biosynthesis protein phzf family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000004151 165.0
MMD2_k127_1007844_6 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000000000000006408 176.0
MMD2_k127_1007844_7 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000009791 151.0
MMD2_k127_1007844_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000003532 124.0
MMD2_k127_1007844_9 Transcriptional regulator - - - 0.0000000000000000000000000008137 125.0
MMD2_k127_1017536_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 456.0
MMD2_k127_1017536_1 FAD binding domain K00486 - 1.14.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 381.0
MMD2_k127_1017536_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 300.0
MMD2_k127_1017536_3 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000003335 228.0
MMD2_k127_1017536_4 PFAM TspO MBR family protein K05770 - - 0.0000000000000000000000000000000000000000000000000000000005751 207.0
MMD2_k127_1017536_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000002506 64.0
MMD2_k127_1030439_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.697e-233 730.0
MMD2_k127_1030439_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 609.0
MMD2_k127_1030439_10 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007167 244.0
MMD2_k127_1030439_11 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000074 231.0
MMD2_k127_1030439_12 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000003106 146.0
MMD2_k127_1030439_13 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000005522 142.0
MMD2_k127_1030439_14 SCP-2 sterol transfer family - - - 0.000000000000000000007476 100.0
MMD2_k127_1030439_16 Membrane fusogenic activity K09806 - - 0.000000000000004878 79.0
MMD2_k127_1030439_17 MacB-like periplasmic core domain - - - 0.000000000000006313 78.0
MMD2_k127_1030439_18 Domain of unknown function (DUF4124) - - - 0.00001312 54.0
MMD2_k127_1030439_2 Magnesium chelatase, subunit K07391 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 484.0
MMD2_k127_1030439_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 420.0
MMD2_k127_1030439_4 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 342.0
MMD2_k127_1030439_5 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 332.0
MMD2_k127_1030439_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 325.0
MMD2_k127_1030439_7 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 300.0
MMD2_k127_1030439_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000322 287.0
MMD2_k127_1030439_9 Response regulator of the LytR AlgR family K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002735 259.0
MMD2_k127_1035972_0 efflux pump K18138,K18322 - - 0.0 1367.0
MMD2_k127_1035972_1 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 606.0
MMD2_k127_1035972_10 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000001478 108.0
MMD2_k127_1035972_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 478.0
MMD2_k127_1035972_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 419.0
MMD2_k127_1035972_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 387.0
MMD2_k127_1035972_5 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 364.0
MMD2_k127_1035972_6 protein, possibly involved in aromatic compounds catabolism K19222 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901576,GO:1901661,GO:1901663 3.1.2.28 0.000000000000000000000000000000000000000000161 164.0
MMD2_k127_1035972_7 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000009626 135.0
MMD2_k127_1035972_8 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000002293 111.0
MMD2_k127_1035972_9 Amidohydrolase family - - - 0.0000000000000000000001376 111.0
MMD2_k127_1056999_0 Domain of unknown function (DUF5117) - - - 5.623e-257 818.0
MMD2_k127_1056999_1 Elongator protein 3, MiaB family, Radical SAM - - - 8.094e-246 783.0
MMD2_k127_1056999_10 - - - - 0.0004406 49.0
MMD2_k127_1056999_2 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 368.0
MMD2_k127_1056999_3 Periplasmic solute binding protein K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 334.0
MMD2_k127_1056999_4 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 299.0
MMD2_k127_1056999_5 ABC-3 protein K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001902 277.0
MMD2_k127_1056999_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001056 239.0
MMD2_k127_1056999_7 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000008254 95.0
MMD2_k127_1056999_8 SnoaL-like domain - - - 0.00000000000000519 84.0
MMD2_k127_1056999_9 EF-hand domain pair - - - 0.0002281 47.0
MMD2_k127_1065493_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 426.0
MMD2_k127_1065493_1 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 406.0
MMD2_k127_1065493_2 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 378.0
MMD2_k127_1065493_3 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 316.0
MMD2_k127_1065493_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001842 237.0
MMD2_k127_1065493_5 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000002276 162.0
MMD2_k127_1065493_6 Translation Initiation Factor K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000002814 137.0
MMD2_k127_1065493_7 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000002383 133.0
MMD2_k127_1065493_8 NUDIX domain - - - 0.0000000000000000000000000005634 123.0
MMD2_k127_1112855_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.411e-283 877.0
MMD2_k127_1112855_1 DNA helicase K03657 - 3.6.4.12 5.353e-279 874.0
MMD2_k127_1112855_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 359.0
MMD2_k127_1112855_11 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 372.0
MMD2_k127_1112855_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 342.0
MMD2_k127_1112855_13 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 338.0
MMD2_k127_1112855_14 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 329.0
MMD2_k127_1112855_15 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 327.0
MMD2_k127_1112855_16 PFAM YicC-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000009127 240.0
MMD2_k127_1112855_17 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000001172 222.0
MMD2_k127_1112855_18 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000124 215.0
MMD2_k127_1112855_19 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000003749 201.0
MMD2_k127_1112855_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.467e-255 806.0
MMD2_k127_1112855_20 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000004426 207.0
MMD2_k127_1112855_21 Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000976 207.0
MMD2_k127_1112855_22 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000001416 183.0
MMD2_k127_1112855_23 PFAM cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000001646 181.0
MMD2_k127_1112855_24 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000001776 179.0
MMD2_k127_1112855_25 pilus assembly protein PilN K02663 - - 0.0000000000000000000000000000000000000000000004908 172.0
MMD2_k127_1112855_26 pilus assembly protein pilp K02665 - - 0.000000000000000000000000000000000000000000003611 169.0
MMD2_k127_1112855_27 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000006623 160.0
MMD2_k127_1112855_28 mRNA catabolic process - - - 0.000000000000000000000000000000000001776 149.0
MMD2_k127_1112855_29 Competence protein - - - 0.000000000000000000000000000000005398 138.0
MMD2_k127_1112855_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.146e-223 711.0
MMD2_k127_1112855_30 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000000726 125.0
MMD2_k127_1112855_31 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000002242 106.0
MMD2_k127_1112855_32 PFAM Ig domain protein, group 1 domain protein - - - 0.0000000000009265 79.0
MMD2_k127_1112855_33 signal sequence binding - - - 0.000000001799 70.0
MMD2_k127_1112855_34 Protein of unknown function (DUF2909) - - - 0.0005338 52.0
MMD2_k127_1112855_4 COG5009 Membrane carboxypeptidase penicillin-binding protein K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 4.074e-218 704.0
MMD2_k127_1112855_5 Type II secretory pathway, component HofQ K02666 - - 6.458e-207 666.0
MMD2_k127_1112855_6 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 465.0
MMD2_k127_1112855_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 413.0
MMD2_k127_1112855_8 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 396.0
MMD2_k127_1112855_9 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 368.0
MMD2_k127_111886_0 E1-E2 ATPase K01535 - 3.6.3.6 1.193e-294 932.0
MMD2_k127_111886_1 ABC-type sugar transport system periplasmic component K17315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 588.0
MMD2_k127_111886_2 ABC-type sugar transport system, permease component K02026,K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 425.0
MMD2_k127_111886_3 COG1175 ABC-type sugar transport systems permease components K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 409.0
MMD2_k127_111886_4 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 272.0
MMD2_k127_11483_0 DEAD DEAH box K03724 - - 0.0 1365.0
MMD2_k127_11483_1 PFAM PrkA AAA K07180 - - 1.867e-303 944.0
MMD2_k127_11483_10 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 336.0
MMD2_k127_11483_11 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 297.0
MMD2_k127_11483_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003658 259.0
MMD2_k127_11483_13 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000576 256.0
MMD2_k127_11483_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000003182 224.0
MMD2_k127_11483_15 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000000003143 205.0
MMD2_k127_11483_16 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000006867 197.0
MMD2_k127_11483_17 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001538 190.0
MMD2_k127_11483_18 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000006367 187.0
MMD2_k127_11483_19 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000008728 169.0
MMD2_k127_11483_2 CoA binding domain K09181 - - 2.085e-292 928.0
MMD2_k127_11483_20 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000001548 155.0
MMD2_k127_11483_21 acetyltransferase - - - 0.0000000000000000000000000000000000004204 159.0
MMD2_k127_11483_22 Acetyltransferase - - - 0.0000000000000000000000000002664 126.0
MMD2_k127_11483_23 - - - - 0.00000000000000001228 93.0
MMD2_k127_11483_24 - - - - 0.000002623 55.0
MMD2_k127_11483_3 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 626.0
MMD2_k127_11483_4 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 593.0
MMD2_k127_11483_5 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 414.0
MMD2_k127_11483_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 399.0
MMD2_k127_11483_7 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 417.0
MMD2_k127_11483_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 361.0
MMD2_k127_11483_9 (ABC) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 357.0
MMD2_k127_1167945_0 Concanavalin A-like lectin/glucanases superfamily - - - 2.446e-266 849.0
MMD2_k127_1167945_1 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 1.281e-260 832.0
MMD2_k127_1167945_10 Amidohydrolase K10221 - 3.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 403.0
MMD2_k127_1167945_11 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 377.0
MMD2_k127_1167945_12 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
MMD2_k127_1167945_13 ABC-type molybdate transport system, permease component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 313.0
MMD2_k127_1167945_14 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 302.0
MMD2_k127_1167945_15 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002155 271.0
MMD2_k127_1167945_16 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186,K16875 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000001054 267.0
MMD2_k127_1167945_17 YdjC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004321 284.0
MMD2_k127_1167945_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001669 281.0
MMD2_k127_1167945_19 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002339 265.0
MMD2_k127_1167945_2 - - - - 1.104e-197 629.0
MMD2_k127_1167945_20 COG3103 SH3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006633 245.0
MMD2_k127_1167945_21 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000003389 220.0
MMD2_k127_1167945_22 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000000000000000000000000008316 226.0
MMD2_k127_1167945_23 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000000008296 214.0
MMD2_k127_1167945_24 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001151 222.0
MMD2_k127_1167945_25 Appr-1-p processing - - - 0.0000000000000000000000000000000000000000000000000000003376 198.0
MMD2_k127_1167945_26 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000001369 188.0
MMD2_k127_1167945_27 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000001833 173.0
MMD2_k127_1167945_28 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.000000000000000000000000000000000002553 141.0
MMD2_k127_1167945_3 belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 496.0
MMD2_k127_1167945_30 catalytic domain of components of various dehydrogenase complexes K00658 - 2.3.1.61 0.00000000000000002797 92.0
MMD2_k127_1167945_31 GtrA-like protein - - - 0.000000002872 64.0
MMD2_k127_1167945_4 PrpF protein K16514 - 5.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 479.0
MMD2_k127_1167945_5 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 460.0
MMD2_k127_1167945_6 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 443.0
MMD2_k127_1167945_7 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 421.0
MMD2_k127_1167945_8 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 420.0
MMD2_k127_1167945_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 414.0
MMD2_k127_119218_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 554.0
MMD2_k127_119218_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 449.0
MMD2_k127_119218_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 396.0
MMD2_k127_119218_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005502 292.0
MMD2_k127_119218_4 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000005067 249.0
MMD2_k127_119218_5 PFAM molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000001428 191.0
MMD2_k127_119218_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000002571 193.0
MMD2_k127_119218_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003898 140.0
MMD2_k127_119218_8 MobA-related protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000006907 119.0
MMD2_k127_119218_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000004318 65.0
MMD2_k127_1258751_0 cytochrome c biogenesis protein - - - 3.864e-247 776.0
MMD2_k127_1258751_1 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 2.687e-230 739.0
MMD2_k127_1258751_10 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
MMD2_k127_1258751_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000004924 204.0
MMD2_k127_1258751_12 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000000000000000000000000000109 181.0
MMD2_k127_1258751_13 Membrane - - - 0.00000000000000000000000000000000000000004377 173.0
MMD2_k127_1258751_14 Domain of unknown function (DUF4129) - - - 0.00000000000000000000000000000000001633 144.0
MMD2_k127_1258751_15 - - - - 0.000000000000000000000000000000006981 134.0
MMD2_k127_1258751_16 - - - - 0.0000000000000000000000003887 110.0
MMD2_k127_1258751_17 membrane protein domain - - - 0.000000000000000000000009089 108.0
MMD2_k127_1258751_18 response regulator - - - 0.00000000000002618 78.0
MMD2_k127_1258751_2 COG4993 Glucose dehydrogenase - - - 1.775e-229 731.0
MMD2_k127_1258751_3 COG4993 Glucose dehydrogenase - - - 2.127e-220 716.0
MMD2_k127_1258751_4 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 618.0
MMD2_k127_1258751_5 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 510.0
MMD2_k127_1258751_6 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 437.0
MMD2_k127_1258751_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 407.0
MMD2_k127_1258751_8 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 317.0
MMD2_k127_1258751_9 methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000216 228.0
MMD2_k127_1344679_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 7.736e-283 884.0
MMD2_k127_1344679_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.175e-278 882.0
MMD2_k127_1344679_10 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 422.0
MMD2_k127_1344679_11 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 412.0
MMD2_k127_1344679_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 356.0
MMD2_k127_1344679_13 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 354.0
MMD2_k127_1344679_14 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 348.0
MMD2_k127_1344679_15 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
MMD2_k127_1344679_16 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 338.0
MMD2_k127_1344679_17 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 311.0
MMD2_k127_1344679_18 Two component response regulator for the phosphate regulon K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 301.0
MMD2_k127_1344679_19 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002939 282.0
MMD2_k127_1344679_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 637.0
MMD2_k127_1344679_20 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002279 272.0
MMD2_k127_1344679_21 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000025 240.0
MMD2_k127_1344679_22 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000002157 233.0
MMD2_k127_1344679_23 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000003449 180.0
MMD2_k127_1344679_24 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000004249 162.0
MMD2_k127_1344679_25 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000005579 163.0
MMD2_k127_1344679_26 Glycoprotease family K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000000002117 140.0
MMD2_k127_1344679_27 Belongs to the skp family K06142 - - 0.000000000000000000000000003832 119.0
MMD2_k127_1344679_28 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000001954 114.0
MMD2_k127_1344679_29 Protein conserved in bacteria - - - 0.00000001317 64.0
MMD2_k127_1344679_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 576.0
MMD2_k127_1344679_4 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 579.0
MMD2_k127_1344679_5 Domain of unknown function (DUF3333) K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 560.0
MMD2_k127_1344679_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 461.0
MMD2_k127_1344679_7 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 456.0
MMD2_k127_1344679_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 436.0
MMD2_k127_1344679_9 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 417.0
MMD2_k127_1351438_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 375.0
MMD2_k127_1351438_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 331.0
MMD2_k127_1351438_10 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000007238 175.0
MMD2_k127_1351438_11 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000285 186.0
MMD2_k127_1351438_12 AntiSigma factor - - - 0.000000000000000000000005805 113.0
MMD2_k127_1351438_13 - - - - 0.0000000000000000000001162 103.0
MMD2_k127_1351438_14 Mo-co oxidoreductase dimerisation domain K05301 - 1.8.2.1 0.0000000000000000000006199 99.0
MMD2_k127_1351438_15 CHAD domain containing protein - - - 0.00000000000000000022 100.0
MMD2_k127_1351438_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
MMD2_k127_1351438_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 312.0
MMD2_k127_1351438_4 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 290.0
MMD2_k127_1351438_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001487 261.0
MMD2_k127_1351438_6 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
MMD2_k127_1351438_7 Cellulose biosynthesis protein BcsQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002134 246.0
MMD2_k127_1351438_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000009121 215.0
MMD2_k127_1351438_9 - - - - 0.0000000000000000000000000000000000000000000000000004417 194.0
MMD2_k127_1366549_0 Nucleoside H+ symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 562.0
MMD2_k127_1366549_1 AP endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 551.0
MMD2_k127_1366549_2 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 541.0
MMD2_k127_1366549_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 470.0
MMD2_k127_1366549_4 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000006741 146.0
MMD2_k127_1366549_5 - - - - 0.000000000000000000001561 99.0
MMD2_k127_1424699_0 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 358.0
MMD2_k127_1424699_1 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 308.0
MMD2_k127_1424699_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000004411 147.0
MMD2_k127_1424699_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000292 138.0
MMD2_k127_1424699_4 atp synthase K02116 GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000004655 57.0
MMD2_k127_1475350_0 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 548.0
MMD2_k127_1475350_1 lipoprotein biosynthetic process K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 291.0
MMD2_k127_1475350_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000009129 137.0
MMD2_k127_1475350_3 Protein of unknown function (DUF3223) - - - 0.0000000001148 67.0
MMD2_k127_1475350_4 - - - - 0.0000002214 57.0
MMD2_k127_1475350_5 Protein of unknown function (DUF3223) - - - 0.000008864 48.0
MMD2_k127_1475350_6 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 - 0.0000168 47.0
MMD2_k127_1475350_7 SdrD B-like domain - - - 0.00006484 54.0
MMD2_k127_1498183_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1056.0
MMD2_k127_1498183_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02674 - - 0.0 1046.0
MMD2_k127_1498183_10 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 445.0
MMD2_k127_1498183_11 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 377.0
MMD2_k127_1498183_12 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 385.0
MMD2_k127_1498183_13 Alpha beta hydrolase K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 368.0
MMD2_k127_1498183_14 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 345.0
MMD2_k127_1498183_15 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 308.0
MMD2_k127_1498183_16 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003893 283.0
MMD2_k127_1498183_17 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004401 261.0
MMD2_k127_1498183_18 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004177 249.0
MMD2_k127_1498183_19 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000005826 265.0
MMD2_k127_1498183_2 Urate oxidase N-terminal - - - 3.032e-295 944.0
MMD2_k127_1498183_20 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000001902 245.0
MMD2_k127_1498183_21 type 4 fimbrial biogenesis transmembrane K02672 - - 0.000000000000000000000000000000000000000000000298 175.0
MMD2_k127_1498183_22 Methionine synthase - - - 0.000000000000000000000000000000000000000000000601 175.0
MMD2_k127_1498183_23 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02671 - - 0.00000000000000000000000000001921 127.0
MMD2_k127_1498183_24 RNA-binding protein - - - 0.0000000000000000000000000002589 117.0
MMD2_k127_1498183_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02673 - - 0.0000000000000000000000000655 124.0
MMD2_k127_1498183_26 pilus assembly protein PilE K02655 - - 0.00000000000000000000000006876 121.0
MMD2_k127_1498183_27 Type II transport protein GspH K08084 - - 0.0000000000000000000001597 105.0
MMD2_k127_1498183_28 overlaps another CDS with the same product name - - - 0.000000000000000004304 91.0
MMD2_k127_1498183_29 copG family - - - 0.00000000000000004457 89.0
MMD2_k127_1498183_3 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit - - - 9.382e-269 842.0
MMD2_k127_1498183_30 lipid glycosylation K16444 - 2.4.1.310 0.0000000000000003535 91.0
MMD2_k127_1498183_31 transcriptional regulator K09017 - - 0.0000000000002208 81.0
MMD2_k127_1498183_32 RHS Repeat - - - 0.0000000000007074 76.0
MMD2_k127_1498183_33 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0000009179 55.0
MMD2_k127_1498183_34 receptor - - - 0.00003664 51.0
MMD2_k127_1498183_4 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 3.984e-246 766.0
MMD2_k127_1498183_5 Myosin-crossreactive antigen K10254 - 4.2.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 576.0
MMD2_k127_1498183_6 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 582.0
MMD2_k127_1498183_7 Protein involved in UDP-N-acetylmuramate dehydrogenase activity and amino sugar metabolic process K05797 - 1.17.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 557.0
MMD2_k127_1498183_8 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 549.0
MMD2_k127_1498183_9 lipid glycosylation K16444 - 2.4.1.310 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 469.0
MMD2_k127_1585304_0 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000001703 218.0
MMD2_k127_1585304_1 4Fe-4S binding domain - - - 0.000000000000000000000000000004498 133.0
MMD2_k127_1585304_2 Belongs to the UPF0235 family K09131 - - 0.000000000001889 71.0
MMD2_k127_1585304_3 FMN_bind - - - 0.00000000009909 70.0
MMD2_k127_1585304_4 - - - - 0.000000008558 64.0
MMD2_k127_1585304_5 Bacterial regulatory proteins, tetR family - - - 0.0002357 51.0
MMD2_k127_1589031_0 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 4.147e-217 697.0
MMD2_k127_1589031_1 Protein of unknown function (DUF1800) - - - 3.498e-205 653.0
MMD2_k127_1589031_10 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 358.0
MMD2_k127_1589031_11 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 367.0
MMD2_k127_1589031_12 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 359.0
MMD2_k127_1589031_13 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 323.0
MMD2_k127_1589031_14 PFAM Nickel transport complex, NikM subunit, transmembrane K02009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 316.0
MMD2_k127_1589031_15 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003108 276.0
MMD2_k127_1589031_16 ATPases associated with a variety of cellular activities K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004013 249.0
MMD2_k127_1589031_17 Asp Glu hydantoin racemase K01799,K06033 - 4.1.1.76,5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000007624 246.0
MMD2_k127_1589031_18 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002725 249.0
MMD2_k127_1589031_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000003758 228.0
MMD2_k127_1589031_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 634.0
MMD2_k127_1589031_20 - - - - 0.000000000000000000000000000000000000000000000000000000001911 207.0
MMD2_k127_1589031_21 - - - - 0.00000000000000000000000000000000000000000000000000000005267 216.0
MMD2_k127_1589031_22 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000001289 206.0
MMD2_k127_1589031_23 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03825 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 - 0.00000000000000000000000000000000000000000000000002849 184.0
MMD2_k127_1589031_24 Zinc-uptake complex component A periplasmic - - - 0.000000000000000000000000000000000000000000000006154 194.0
MMD2_k127_1589031_25 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000272 156.0
MMD2_k127_1589031_26 - - - - 0.0000000000000000000000000000000000000004902 166.0
MMD2_k127_1589031_27 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000227 159.0
MMD2_k127_1589031_28 Belongs to the ompA family - - - 0.00000000000000000000000000000002993 142.0
MMD2_k127_1589031_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 608.0
MMD2_k127_1589031_30 - - - - 0.00000000000000000000000000004459 121.0
MMD2_k127_1589031_31 Protein of unknown function (DUF4242) - - - 0.0000000000000000000001099 111.0
MMD2_k127_1589031_32 - - - - 0.0000000000000004232 87.0
MMD2_k127_1589031_33 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000162 80.0
MMD2_k127_1589031_34 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000001833 63.0
MMD2_k127_1589031_4 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 572.0
MMD2_k127_1589031_5 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 572.0
MMD2_k127_1589031_6 FAD linked oxidase domain protein K05797 - 1.17.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 544.0
MMD2_k127_1589031_8 Twin-arginine translocation pathway signal sequence - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 400.0
MMD2_k127_1589031_9 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 363.0
MMD2_k127_1616233_0 Asparagine synthase K01953 - 6.3.5.4 2.095e-307 955.0
MMD2_k127_1616233_1 Asparagine synthase K01953 - 6.3.5.4 1.187e-224 713.0
MMD2_k127_1616233_10 Glycosyl transferases group 1 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 471.0
MMD2_k127_1616233_11 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 470.0
MMD2_k127_1616233_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 437.0
MMD2_k127_1616233_13 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 424.0
MMD2_k127_1616233_14 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 424.0
MMD2_k127_1616233_15 TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 417.0
MMD2_k127_1616233_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 426.0
MMD2_k127_1616233_17 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 413.0
MMD2_k127_1616233_18 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 387.0
MMD2_k127_1616233_19 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 384.0
MMD2_k127_1616233_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.014e-211 665.0
MMD2_k127_1616233_20 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 374.0
MMD2_k127_1616233_21 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 358.0
MMD2_k127_1616233_22 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 340.0
MMD2_k127_1616233_23 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 342.0
MMD2_k127_1616233_24 Polysaccharide chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 331.0
MMD2_k127_1616233_25 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 314.0
MMD2_k127_1616233_26 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 317.0
MMD2_k127_1616233_27 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 319.0
MMD2_k127_1616233_28 HAD-superfamily phosphatase subfamily IIIC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 321.0
MMD2_k127_1616233_29 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 306.0
MMD2_k127_1616233_3 PQQ enzyme repeat K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 596.0
MMD2_k127_1616233_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001956 273.0
MMD2_k127_1616233_31 asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004338 276.0
MMD2_k127_1616233_32 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
MMD2_k127_1616233_33 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001627 243.0
MMD2_k127_1616233_34 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004504 241.0
MMD2_k127_1616233_35 PEP-CTERM system TPR-repeat lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000593 253.0
MMD2_k127_1616233_36 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000003709 226.0
MMD2_k127_1616233_37 ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000001344 227.0
MMD2_k127_1616233_38 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000001222 216.0
MMD2_k127_1616233_39 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000000000000000000000000109 226.0
MMD2_k127_1616233_4 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 556.0
MMD2_k127_1616233_40 transferase activity, transferring glycosyl groups K09809 - 2.7.8.12 0.0000000000000000000000000000000000000000000000000695 192.0
MMD2_k127_1616233_41 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.0000000000000000000000000000000000000000001135 171.0
MMD2_k127_1616233_42 TPR repeat - - - 0.000000000000000000000000000000000002751 147.0
MMD2_k127_1616233_43 Methyltransferase type 12 - - - 0.000000000000000000000006956 112.0
MMD2_k127_1616233_44 outer membrane autotransporter barrel domain - - - 0.0000000000000000000005411 104.0
MMD2_k127_1616233_45 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000001457 76.0
MMD2_k127_1616233_46 Protein conserved in bacteria - - - 0.00000000000004067 85.0
MMD2_k127_1616233_47 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000001489 63.0
MMD2_k127_1616233_48 Glycosyltransferase like family 2 - - - 0.00000005371 64.0
MMD2_k127_1616233_49 cellulase activity K12287 - - 0.00000007907 61.0
MMD2_k127_1616233_5 UDP binding domain K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 533.0
MMD2_k127_1616233_50 Carrier of the growing fatty acid chain in fatty acid biosynthesis K01647,K02078 - 2.3.3.1 0.000000707 55.0
MMD2_k127_1616233_6 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 533.0
MMD2_k127_1616233_7 HAD-superfamily phosphatase subfamily IIIC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 522.0
MMD2_k127_1616233_8 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 479.0
MMD2_k127_1616233_9 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 470.0
MMD2_k127_1626999_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.28e-207 657.0
MMD2_k127_1626999_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 492.0
MMD2_k127_1626999_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 422.0
MMD2_k127_1626999_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 386.0
MMD2_k127_1626999_4 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 347.0
MMD2_k127_1626999_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 319.0
MMD2_k127_1626999_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002771 295.0
MMD2_k127_1626999_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000007081 254.0
MMD2_k127_1626999_8 protein, YerC YecD - - - 0.0000000000000000000000000001096 117.0
MMD2_k127_1637345_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 570.0
MMD2_k127_1637345_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 529.0
MMD2_k127_1637345_10 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 317.0
MMD2_k127_1637345_11 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 309.0
MMD2_k127_1637345_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 301.0
MMD2_k127_1637345_13 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000008215 235.0
MMD2_k127_1637345_14 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000597 237.0
MMD2_k127_1637345_15 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000007461 214.0
MMD2_k127_1637345_16 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000009144 206.0
MMD2_k127_1637345_17 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000002381 198.0
MMD2_k127_1637345_18 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000006057 184.0
MMD2_k127_1637345_19 amp-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000006997 163.0
MMD2_k127_1637345_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 516.0
MMD2_k127_1637345_20 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.00000000000000000000000000000000000000005215 153.0
MMD2_k127_1637345_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000001252 142.0
MMD2_k127_1637345_22 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000008425 123.0
MMD2_k127_1637345_23 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000006811 115.0
MMD2_k127_1637345_24 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000004003 114.0
MMD2_k127_1637345_25 DoxX K15977 - - 0.0000000000000000000000005695 115.0
MMD2_k127_1637345_26 PDZ domain - - - 0.0000000000000000000000222 111.0
MMD2_k127_1637345_27 protein conserved in bacteria K15539 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000001709 88.0
MMD2_k127_1637345_29 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000003644 54.0
MMD2_k127_1637345_3 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 518.0
MMD2_k127_1637345_30 - - - - 0.0003561 48.0
MMD2_k127_1637345_4 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 465.0
MMD2_k127_1637345_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 434.0
MMD2_k127_1637345_6 Trypsin-like serine protease K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 436.0
MMD2_k127_1637345_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 410.0
MMD2_k127_1637345_8 recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 387.0
MMD2_k127_1637345_9 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 385.0
MMD2_k127_1647297_0 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K15022 - 1.17.1.10 7.58e-284 883.0
MMD2_k127_1647297_1 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 5.593e-272 848.0
MMD2_k127_1647297_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 470.0
MMD2_k127_1647297_3 - - - - 0.0000000000000004927 92.0
MMD2_k127_165436_0 ABC transporter K15738 - - 4.027e-235 744.0
MMD2_k127_165436_1 Cytochrome c K02198 - - 5.914e-229 729.0
MMD2_k127_165436_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 429.0
MMD2_k127_165436_11 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 409.0
MMD2_k127_165436_12 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 407.0
MMD2_k127_165436_13 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 351.0
MMD2_k127_165436_14 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 338.0
MMD2_k127_165436_15 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 335.0
MMD2_k127_165436_16 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 312.0
MMD2_k127_165436_17 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 307.0
MMD2_k127_165436_18 Glycerophosphoryl diester phosphodiesterase family K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 297.0
MMD2_k127_165436_19 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 289.0
MMD2_k127_165436_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 2.125e-225 737.0
MMD2_k127_165436_20 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005316 277.0
MMD2_k127_165436_21 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009534 264.0
MMD2_k127_165436_22 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000379 273.0
MMD2_k127_165436_23 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000001453 247.0
MMD2_k127_165436_24 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000002307 238.0
MMD2_k127_165436_25 Alkyl hydroperoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001006 228.0
MMD2_k127_165436_26 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000006542 228.0
MMD2_k127_165436_27 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000341 240.0
MMD2_k127_165436_28 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000007922 209.0
MMD2_k127_165436_29 peptidase - - - 0.000000000000000000000000000000000000000000000000000001173 203.0
MMD2_k127_165436_3 Enoyl-CoA hydratase/isomerase - - - 2.269e-208 667.0
MMD2_k127_165436_30 COG0526 Thiol-disulfide isomerase and thioredoxins K02199 - - 0.0000000000000000000000000000000000000000000000000008149 192.0
MMD2_k127_165436_31 Pilus assembly protein PilZ K02676 - - 0.000000000000000000000000000000000000000000000002312 177.0
MMD2_k127_165436_32 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000001713 174.0
MMD2_k127_165436_33 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000002934 173.0
MMD2_k127_165436_34 phosphate regulon transcriptional regulatory protein PhoB K07657 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000002632 162.0
MMD2_k127_165436_35 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000006717 155.0
MMD2_k127_165436_36 subunit of a heme lyase K02200,K04017 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.00000000000000000000000000000000002629 145.0
MMD2_k127_165436_37 the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA K02341 - 2.7.7.7 0.0000000000000000000000000000000001172 151.0
MMD2_k127_165436_38 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000000000000003959 140.0
MMD2_k127_165436_39 Cytochrome C biogenesis K02200 - - 0.000000000000000000000000000000009756 140.0
MMD2_k127_165436_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 580.0
MMD2_k127_165436_40 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000000000000001534 136.0
MMD2_k127_165436_41 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000001967 123.0
MMD2_k127_165436_42 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000008882 92.0
MMD2_k127_165436_43 general secretion pathway protein h K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000001106 98.0
MMD2_k127_165436_44 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000002774 87.0
MMD2_k127_165436_45 general secretion pathway protein K02246,K02456,K02457,K02458 - - 0.000000000000002135 81.0
MMD2_k127_165436_46 type II secretion system protein N K02463 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000001741 77.0
MMD2_k127_165436_47 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000503 75.0
MMD2_k127_165436_48 Type II secretion system (T2SS), protein M - - - 0.00000000006264 75.0
MMD2_k127_165436_49 (FHA) domain - - - 0.000000007103 68.0
MMD2_k127_165436_5 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 516.0
MMD2_k127_165436_50 AAA domain - - - 0.000000209 63.0
MMD2_k127_165436_51 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.00004836 53.0
MMD2_k127_165436_52 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.0001185 49.0
MMD2_k127_165436_6 aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 483.0
MMD2_k127_165436_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 464.0
MMD2_k127_165436_8 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 464.0
MMD2_k127_165436_9 selenide, water dikinase activity K01008 GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 441.0
MMD2_k127_1686517_0 outer membrane autotransporter barrel - - - 0.0 2636.0
MMD2_k127_1686517_1 FAD linked oxidase domain protein K05797 - 1.17.99.1 4.539e-280 870.0
MMD2_k127_1686517_10 transcription activator, effector binding K13652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 363.0
MMD2_k127_1686517_11 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 376.0
MMD2_k127_1686517_12 multidrug resistance efflux pump K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 346.0
MMD2_k127_1686517_13 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 329.0
MMD2_k127_1686517_14 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 293.0
MMD2_k127_1686517_15 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001177 285.0
MMD2_k127_1686517_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000879 285.0
MMD2_k127_1686517_17 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000006871 263.0
MMD2_k127_1686517_18 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000002534 247.0
MMD2_k127_1686517_19 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000001632 233.0
MMD2_k127_1686517_2 Oligopeptidase A K01414 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 6.328e-218 700.0
MMD2_k127_1686517_20 - - - - 0.00000000000000000000000000000000000000000000000000000001024 210.0
MMD2_k127_1686517_21 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000001719 198.0
MMD2_k127_1686517_22 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000135 181.0
MMD2_k127_1686517_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000003846 161.0
MMD2_k127_1686517_24 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000009661 174.0
MMD2_k127_1686517_25 TfoX N-terminal domain - - - 0.0000000000000000000000000000000000003235 143.0
MMD2_k127_1686517_26 - - - - 0.00000000000000000000000000000008121 129.0
MMD2_k127_1686517_27 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000006686 103.0
MMD2_k127_1686517_28 - - - - 0.00000000000000000000001244 111.0
MMD2_k127_1686517_29 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000131 117.0
MMD2_k127_1686517_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 523.0
MMD2_k127_1686517_31 bis(5'-adenosyl)-triphosphatase activity K02503 - - 0.000000000000000254 90.0
MMD2_k127_1686517_32 - - - - 0.000000001784 63.0
MMD2_k127_1686517_33 Acetyltransferase (GNAT) domain - - - 0.0000000408 59.0
MMD2_k127_1686517_4 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 548.0
MMD2_k127_1686517_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 514.0
MMD2_k127_1686517_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 501.0
MMD2_k127_1686517_7 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 441.0
MMD2_k127_1686517_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 432.0
MMD2_k127_1686517_9 epoxide hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 386.0
MMD2_k127_1690724_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 562.0
MMD2_k127_1690724_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 419.0
MMD2_k127_1690724_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 372.0
MMD2_k127_1690724_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004232 211.0
MMD2_k127_1690724_4 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000001733 187.0
MMD2_k127_1690724_5 - - - - 0.00000000000000000000000000000000008284 141.0
MMD2_k127_1690724_6 cell adhesion involved in biofilm formation - - - 0.000003121 59.0
MMD2_k127_1732280_0 receptor K02014 - - 2.829e-311 975.0
MMD2_k127_1732280_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 3.988e-293 919.0
MMD2_k127_1732280_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 4.272e-260 816.0
MMD2_k127_1732280_3 Osmosensitive K+ channel His kinase sensor domain K07646 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009593,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031668,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0065007,GO:0071214,GO:0071470,GO:0071472,GO:0071496,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 364.0
MMD2_k127_1732280_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000004138 227.0
MMD2_k127_1762792_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.292e-257 803.0
MMD2_k127_1762792_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.141e-240 748.0
MMD2_k127_1762792_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000004913 149.0
MMD2_k127_1762792_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000007595 146.0
MMD2_k127_1762792_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000001119 113.0
MMD2_k127_1762792_13 atp synthase K02116 GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000314 48.0
MMD2_k127_1762792_14 PFAM ABC transporter related K06148 - - 0.00003408 53.0
MMD2_k127_1762792_2 Radical SAM - - - 1.358e-205 651.0
MMD2_k127_1762792_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 386.0
MMD2_k127_1762792_4 glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 374.0
MMD2_k127_1762792_5 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 292.0
MMD2_k127_1762792_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000001977 205.0
MMD2_k127_1762792_7 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000457 199.0
MMD2_k127_1762792_8 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000004907 186.0
MMD2_k127_1762792_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000003636 148.0
MMD2_k127_1836125_0 Aminomethyltransferase folate-binding domain - - - 7.767e-258 805.0
MMD2_k127_1836125_1 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 573.0
MMD2_k127_1836125_10 RNA-binding - - - 0.000000000000000000000000000000002813 131.0
MMD2_k127_1836125_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000006002 113.0
MMD2_k127_1836125_12 Haem-degrading - - - 0.000000000000000000000003372 108.0
MMD2_k127_1836125_14 Protein of unknown function (DUF3012) - - - 0.00000000000000844 76.0
MMD2_k127_1836125_15 - - - - 0.00000000000001882 84.0
MMD2_k127_1836125_16 - - - - 0.00000000000001882 79.0
MMD2_k127_1836125_17 - - - - 0.0000008171 61.0
MMD2_k127_1836125_18 MacB-like periplasmic core domain - - - 0.00003012 50.0
MMD2_k127_1836125_2 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 435.0
MMD2_k127_1836125_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 331.0
MMD2_k127_1836125_4 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000002788 258.0
MMD2_k127_1836125_5 response regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000002156 227.0
MMD2_k127_1836125_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000003012 228.0
MMD2_k127_1836125_7 Divergent polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000144 204.0
MMD2_k127_1836125_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002232 190.0
MMD2_k127_1836125_9 - - - - 0.0000000000000000000000000000000000002537 155.0
MMD2_k127_1952778_0 OmpA family - - - 0.0 1935.0
MMD2_k127_1952778_1 domain protein - - - 0.0 1444.0
MMD2_k127_1952778_10 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 532.0
MMD2_k127_1952778_11 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 464.0
MMD2_k127_1952778_12 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 468.0
MMD2_k127_1952778_13 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 467.0
MMD2_k127_1952778_14 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 420.0
MMD2_k127_1952778_15 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 440.0
MMD2_k127_1952778_16 PFAM Sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 399.0
MMD2_k127_1952778_17 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 415.0
MMD2_k127_1952778_18 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 391.0
MMD2_k127_1952778_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 400.0
MMD2_k127_1952778_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1275.0
MMD2_k127_1952778_20 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 401.0
MMD2_k127_1952778_21 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 385.0
MMD2_k127_1952778_22 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 381.0
MMD2_k127_1952778_23 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 387.0
MMD2_k127_1952778_24 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 359.0
MMD2_k127_1952778_25 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 346.0
MMD2_k127_1952778_26 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 341.0
MMD2_k127_1952778_27 transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 340.0
MMD2_k127_1952778_28 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 319.0
MMD2_k127_1952778_29 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 319.0
MMD2_k127_1952778_3 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1042.0
MMD2_k127_1952778_30 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 332.0
MMD2_k127_1952778_31 TIGRFAM anion transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 329.0
MMD2_k127_1952778_32 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 311.0
MMD2_k127_1952778_33 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 299.0
MMD2_k127_1952778_34 Acyltransferase family K11941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005574 284.0
MMD2_k127_1952778_35 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005005 276.0
MMD2_k127_1952778_36 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009892 265.0
MMD2_k127_1952778_37 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000101 268.0
MMD2_k127_1952778_38 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000333 267.0
MMD2_k127_1952778_39 peroxidase activity K00435 - - 0.000000000000000000000000000000000000000000000000000000000000000000000106 256.0
MMD2_k127_1952778_4 Tetratricopeptide repeat - - - 1.6e-322 1032.0
MMD2_k127_1952778_40 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001625 260.0
MMD2_k127_1952778_41 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000272 245.0
MMD2_k127_1952778_42 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000006472 244.0
MMD2_k127_1952778_43 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000006561 240.0
MMD2_k127_1952778_44 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006996 244.0
MMD2_k127_1952778_45 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000001003 215.0
MMD2_k127_1952778_46 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000005695 201.0
MMD2_k127_1952778_47 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000001011 215.0
MMD2_k127_1952778_48 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000001886 205.0
MMD2_k127_1952778_49 Putative FMN-binding domain - - - 0.000000000000000000000000000000000000000000000000000426 194.0
MMD2_k127_1952778_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.483e-240 777.0
MMD2_k127_1952778_50 - - - - 0.0000000000000000000000000000000000000000000000005958 181.0
MMD2_k127_1952778_51 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000001289 182.0
MMD2_k127_1952778_52 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000001388 173.0
MMD2_k127_1952778_53 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.000000000000000000000000000000000000000000001462 168.0
MMD2_k127_1952778_54 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000006848 154.0
MMD2_k127_1952778_55 Phosphatidylethanolamine-binding protein - - - 0.0000000000000000000000000000000000001316 150.0
MMD2_k127_1952778_56 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000598 156.0
MMD2_k127_1952778_57 FMN binding - - - 0.0000000000000000000000000000000002045 141.0
MMD2_k127_1952778_58 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000004902 134.0
MMD2_k127_1952778_59 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000001672 135.0
MMD2_k127_1952778_6 Tetratricopeptide repeat - - - 1.144e-202 664.0
MMD2_k127_1952778_61 - - - - 0.0000000000000000000000000000006905 127.0
MMD2_k127_1952778_62 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000007257 136.0
MMD2_k127_1952778_63 - - - - 0.0000000000000000000000001033 117.0
MMD2_k127_1952778_64 - - - - 0.0000000000000000000000001087 111.0
MMD2_k127_1952778_65 Belongs to the universal stress protein A family - - - 0.000000000000000000000002566 107.0
MMD2_k127_1952778_66 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000000000000008432 100.0
MMD2_k127_1952778_67 - - - - 0.0000000000000000000003422 111.0
MMD2_k127_1952778_68 - - - - 0.00000000000000000208 95.0
MMD2_k127_1952778_69 Universal stress protein family - - - 0.00000000000000009472 91.0
MMD2_k127_1952778_7 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 635.0
MMD2_k127_1952778_70 - - - - 0.0000000000000001299 83.0
MMD2_k127_1952778_72 - - - - 0.0000000000000178 80.0
MMD2_k127_1952778_73 Bacterial protein of unknown function (DUF945) - - - 0.000000000002599 81.0
MMD2_k127_1952778_74 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000003757 79.0
MMD2_k127_1952778_75 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000002332 71.0
MMD2_k127_1952778_76 SnoaL-like domain - - - 0.000001146 58.0
MMD2_k127_1952778_77 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00001529 52.0
MMD2_k127_1952778_78 - - - - 0.00004073 54.0
MMD2_k127_1952778_8 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 576.0
MMD2_k127_1952778_9 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 570.0
MMD2_k127_1957302_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1256.0
MMD2_k127_1957302_1 Belongs to the ABC transporter superfamily K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 2.942e-220 695.0
MMD2_k127_1957302_10 MOSC domain - - - 0.00000000000000000000000000000000000000000000000001645 188.0
MMD2_k127_1957302_11 Exopolysaccharide synthesis, ExoD - - - 0.000000000000000000000000000000000000000001889 164.0
MMD2_k127_1957302_12 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000005144 158.0
MMD2_k127_1957302_15 - - - - 0.0000000000000000000000001733 108.0
MMD2_k127_1957302_16 TIGRFAM conserved - - - 0.00000000009095 71.0
MMD2_k127_1957302_17 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000001567 63.0
MMD2_k127_1957302_19 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor - - - 0.000004602 56.0
MMD2_k127_1957302_2 COG2943 Membrane glycosyltransferase K03669 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009628,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016740,GO:0016757,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:0071944,GO:1901576 - 4.773e-214 692.0
MMD2_k127_1957302_3 Major Facilitator Superfamily - - - 7.852e-199 627.0
MMD2_k127_1957302_4 Binding-protein-dependent transport system inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 519.0
MMD2_k127_1957302_5 transport system, permease component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 513.0
MMD2_k127_1957302_6 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 479.0
MMD2_k127_1957302_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 460.0
MMD2_k127_1957302_8 N-terminal TM domain of oligopeptide transport permease C K02034 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 372.0
MMD2_k127_1957302_9 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000001484 224.0
MMD2_k127_1973602_0 Belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 3.12e-229 724.0
MMD2_k127_1973602_1 4-hydroxy-tetrahydrodipicolinate synthase K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 392.0
MMD2_k127_1973602_2 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04101,K05713 - 1.13.11.16,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 416.0
MMD2_k127_1973602_3 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 365.0
MMD2_k127_1973602_4 PFAM Extradiol ring-cleavage dioxygenase LigAB LigA subunit - - - 0.00000000000000000000000000000000008996 135.0
MMD2_k127_1973602_5 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.0000000000000000000000000000001923 128.0
MMD2_k127_2002249_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 9.253e-230 724.0
MMD2_k127_2002249_1 Glucose / Sorbosone dehydrogenase - - - 7.777e-198 640.0
MMD2_k127_2002249_2 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.911e-196 617.0
MMD2_k127_2002249_3 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 486.0
MMD2_k127_2002249_4 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 308.0
MMD2_k127_2002249_5 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 314.0
MMD2_k127_2002249_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000002011 156.0
MMD2_k127_2002249_7 methyltransferase - - - 0.00000000000000000001724 94.0
MMD2_k127_2002249_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00001112 54.0
MMD2_k127_2003098_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.698e-239 765.0
MMD2_k127_2003098_1 Adenylate cyclase - - - 4.533e-234 742.0
MMD2_k127_2003098_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000005706 219.0
MMD2_k127_2003098_11 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.00000000000000000000000000000000000000000000000000000000006264 220.0
MMD2_k127_2003098_12 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000002225 201.0
MMD2_k127_2003098_13 - - - - 0.0000000000000000000000000000000000000000000000000009334 188.0
MMD2_k127_2003098_14 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000008187 181.0
MMD2_k127_2003098_15 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000006152 183.0
MMD2_k127_2003098_16 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000013 133.0
MMD2_k127_2003098_17 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000006509 108.0
MMD2_k127_2003098_18 Trm112p-like protein - - - 0.000000000000000006325 85.0
MMD2_k127_2003098_19 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane - - - 0.00000000000000002307 91.0
MMD2_k127_2003098_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 614.0
MMD2_k127_2003098_3 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 595.0
MMD2_k127_2003098_4 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 336.0
MMD2_k127_2003098_5 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006153 288.0
MMD2_k127_2003098_6 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006259 268.0
MMD2_k127_2003098_7 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001856 269.0
MMD2_k127_2003098_8 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741,K03892 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 250.0
MMD2_k127_2003098_9 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000314 248.0
MMD2_k127_2040128_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 603.0
MMD2_k127_2040128_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 589.0
MMD2_k127_2040128_10 PFAM LppC K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000568 263.0
MMD2_k127_2040128_11 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006751 252.0
MMD2_k127_2040128_12 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000004222 138.0
MMD2_k127_2040128_13 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000004286 144.0
MMD2_k127_2040128_14 Belongs to the BolA IbaG family - - - 0.0000000000000000000001158 99.0
MMD2_k127_2040128_15 Belongs to the UPF0102 family K07460 - - 0.000000000000000000001093 98.0
MMD2_k127_2040128_16 - - - - 0.000000000004646 68.0
MMD2_k127_2040128_17 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.000000277 63.0
MMD2_k127_2040128_18 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0004705 50.0
MMD2_k127_2040128_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 407.0
MMD2_k127_2040128_3 ABC transporter ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 345.0
MMD2_k127_2040128_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 311.0
MMD2_k127_2040128_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 302.0
MMD2_k127_2040128_6 Belongs to the peptidase S1C family K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 293.0
MMD2_k127_2040128_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000002648 266.0
MMD2_k127_2040128_8 Stringent starvation protein A K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001209 265.0
MMD2_k127_2040128_9 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000003052 248.0
MMD2_k127_2062829_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1323.0
MMD2_k127_2062829_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.844e-252 790.0
MMD2_k127_2062829_10 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 297.0
MMD2_k127_2062829_11 Histidine kinase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002099 295.0
MMD2_k127_2062829_12 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000211 256.0
MMD2_k127_2062829_13 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000007444 236.0
MMD2_k127_2062829_14 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001854 241.0
MMD2_k127_2062829_15 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000007006 223.0
MMD2_k127_2062829_16 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000005374 216.0
MMD2_k127_2062829_17 universal stress protein K14055 - - 0.00000000000000000000000000000000000000000000000003103 191.0
MMD2_k127_2062829_18 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000000000000000005351 186.0
MMD2_k127_2062829_19 - - - - 0.0000000000000000000000000000000000008296 146.0
MMD2_k127_2062829_2 Phosphate acyltransferases - - - 1.373e-194 646.0
MMD2_k127_2062829_20 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000107 145.0
MMD2_k127_2062829_21 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000001981 104.0
MMD2_k127_2062829_22 Universal stress protein family K14055 - - 0.0000000000000000002163 100.0
MMD2_k127_2062829_23 Protein of unknown function (DUF3240) - - - 0.0000000000000001161 84.0
MMD2_k127_2062829_24 Phosphopantetheine attachment site - - - 0.0000000000002822 82.0
MMD2_k127_2062829_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 600.0
MMD2_k127_2062829_4 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 488.0
MMD2_k127_2062829_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 441.0
MMD2_k127_2062829_6 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 422.0
MMD2_k127_2062829_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 370.0
MMD2_k127_2062829_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 321.0
MMD2_k127_2062829_9 PhoPQ-activated pathogenicity-related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 308.0
MMD2_k127_2171087_0 Monomeric isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1064.0
MMD2_k127_2171087_1 RNA polymerase sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 569.0
MMD2_k127_2171087_10 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000001908 145.0
MMD2_k127_2171087_11 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000002146 104.0
MMD2_k127_2171087_14 SnoaL-like domain - - - 0.0008692 46.0
MMD2_k127_2171087_2 Glucose inhibited division protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 566.0
MMD2_k127_2171087_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 586.0
MMD2_k127_2171087_4 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 402.0
MMD2_k127_2171087_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000254 276.0
MMD2_k127_2171087_6 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001148 250.0
MMD2_k127_2171087_7 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000009819 187.0
MMD2_k127_2171087_8 - - - - 0.00000000000000000000000000000000000000000007314 181.0
MMD2_k127_2171087_9 - - - - 0.00000000000000000000000000000000000006317 146.0
MMD2_k127_2177061_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1185.0
MMD2_k127_2177061_1 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 2.517e-311 1002.0
MMD2_k127_2177061_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 496.0
MMD2_k127_2177061_11 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 481.0
MMD2_k127_2177061_12 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 458.0
MMD2_k127_2177061_13 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 442.0
MMD2_k127_2177061_14 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 454.0
MMD2_k127_2177061_15 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 405.0
MMD2_k127_2177061_16 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 411.0
MMD2_k127_2177061_17 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 390.0
MMD2_k127_2177061_18 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 377.0
MMD2_k127_2177061_19 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 369.0
MMD2_k127_2177061_2 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 2.329e-262 831.0
MMD2_k127_2177061_20 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 357.0
MMD2_k127_2177061_21 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 345.0
MMD2_k127_2177061_22 Preprotein translocase subunit TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 335.0
MMD2_k127_2177061_23 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 339.0
MMD2_k127_2177061_24 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 329.0
MMD2_k127_2177061_25 Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA K11935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 342.0
MMD2_k127_2177061_26 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 316.0
MMD2_k127_2177061_27 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 304.0
MMD2_k127_2177061_28 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 317.0
MMD2_k127_2177061_29 ChrR Cupin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 304.0
MMD2_k127_2177061_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 6.789e-230 727.0
MMD2_k127_2177061_30 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 293.0
MMD2_k127_2177061_31 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 288.0
MMD2_k127_2177061_32 signal transduction histidine kinase K07637 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002136 295.0
MMD2_k127_2177061_33 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008463 285.0
MMD2_k127_2177061_34 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004334 270.0
MMD2_k127_2177061_35 Maleylacetoacetate isomerase K01801 - 5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002333 252.0
MMD2_k127_2177061_36 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000643 240.0
MMD2_k127_2177061_37 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000137 239.0
MMD2_k127_2177061_38 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000003357 224.0
MMD2_k127_2177061_39 - - - - 0.000000000000000000000000000000000000000000000000000000000000001277 230.0
MMD2_k127_2177061_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 9.49e-208 655.0
MMD2_k127_2177061_40 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000127 214.0
MMD2_k127_2177061_41 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000004436 183.0
MMD2_k127_2177061_42 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000001932 166.0
MMD2_k127_2177061_43 - - - - 0.0000000000000000000000000000000000000000000303 177.0
MMD2_k127_2177061_44 - - - - 0.000000000000000000000000000000000000000004216 159.0
MMD2_k127_2177061_45 Bacterial transcription activator, effector binding domain K13652,K13653 - - 0.000000000000000000000000000000000000000005477 166.0
MMD2_k127_2177061_46 WLM domain K07043 - - 0.000000000000000000000000000000000000001682 156.0
MMD2_k127_2177061_47 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000001085 162.0
MMD2_k127_2177061_48 DNA mismatch repair protein MutT - - - 0.000000000000000000000000000000000001418 156.0
MMD2_k127_2177061_49 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000007137 132.0
MMD2_k127_2177061_5 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 593.0
MMD2_k127_2177061_50 17 kDa surface antigen - - - 0.000000000000000000000000000006323 126.0
MMD2_k127_2177061_51 protein acetylation - - - 0.00000000000000000009321 95.0
MMD2_k127_2177061_52 PgaD-like protein K11937 - - 0.00000000000000005606 94.0
MMD2_k127_2177061_55 competence protein - - - 0.00000004595 65.0
MMD2_k127_2177061_56 COG0551 Zn-finger domain associated with topoisomerase type I - - - 0.000001349 57.0
MMD2_k127_2177061_57 Tetratricopeptide repeat - - - 0.000005196 57.0
MMD2_k127_2177061_59 Membrane-bound serine protease (ClpP class) K07403 - - 0.00004194 54.0
MMD2_k127_2177061_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 562.0
MMD2_k127_2177061_7 Polysaccharide deacetylase K11931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 568.0
MMD2_k127_2177061_8 Glycosyl transferase family 21 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 569.0
MMD2_k127_2177061_9 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 547.0
MMD2_k127_219478_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2163.0
MMD2_k127_219478_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1585.0
MMD2_k127_219478_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 323.0
MMD2_k127_219478_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 300.0
MMD2_k127_219478_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000009025 235.0
MMD2_k127_219478_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000002805 178.0
MMD2_k127_219478_6 Ribosomal protein L7/L12 dimerisation domain - - - 0.000000000000000000000000000000000000001729 150.0
MMD2_k127_219478_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000003061 117.0
MMD2_k127_219478_8 translation elongation factor activity K02358 - - 0.00000000000000004178 80.0
MMD2_k127_219478_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000009229 49.0
MMD2_k127_2249978_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 565.0
MMD2_k127_2249978_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 312.0
MMD2_k127_235888_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 1.131e-257 803.0
MMD2_k127_235888_1 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 2.856e-220 699.0
MMD2_k127_235888_10 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 522.0
MMD2_k127_235888_11 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 526.0
MMD2_k127_235888_12 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 492.0
MMD2_k127_235888_13 Tannase and feruloyl esterase K21105 - 3.1.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 494.0
MMD2_k127_235888_14 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 475.0
MMD2_k127_235888_15 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 453.0
MMD2_k127_235888_16 PFAM amidohydrolase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 424.0
MMD2_k127_235888_17 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 426.0
MMD2_k127_235888_18 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 406.0
MMD2_k127_235888_19 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 401.0
MMD2_k127_235888_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.1e-216 679.0
MMD2_k127_235888_20 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 384.0
MMD2_k127_235888_21 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 389.0
MMD2_k127_235888_22 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 358.0
MMD2_k127_235888_23 cytochrome K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 360.0
MMD2_k127_235888_24 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 353.0
MMD2_k127_235888_25 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 359.0
MMD2_k127_235888_26 Short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 340.0
MMD2_k127_235888_27 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 346.0
MMD2_k127_235888_28 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 321.0
MMD2_k127_235888_29 Lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 304.0
MMD2_k127_235888_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.645e-205 647.0
MMD2_k127_235888_30 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 306.0
MMD2_k127_235888_31 Methyltransferase K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 301.0
MMD2_k127_235888_32 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006544 267.0
MMD2_k127_235888_33 cell wall glycoprotein biosynthetic process K00344,K01809,K01840,K03431,K04035,K15778,K16881 GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.14.13.81,1.6.5.5,2.7.7.13,5.3.1.8,5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000007927 274.0
MMD2_k127_235888_34 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001386 259.0
MMD2_k127_235888_35 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002421 252.0
MMD2_k127_235888_36 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000003255 243.0
MMD2_k127_235888_37 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000006244 232.0
MMD2_k127_235888_38 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000004128 221.0
MMD2_k127_235888_39 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000004503 200.0
MMD2_k127_235888_4 Metallopeptidase family M24 - - - 1.153e-199 631.0
MMD2_k127_235888_40 - - - - 0.00000000000000000000000000000000000000000000000000345 197.0
MMD2_k127_235888_41 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.00000000000000000000000000000000000000000002912 174.0
MMD2_k127_235888_42 TRAP-type C4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000000000000000000941 136.0
MMD2_k127_235888_43 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000008262 139.0
MMD2_k127_235888_44 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000004194 134.0
MMD2_k127_235888_45 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000002211 128.0
MMD2_k127_235888_46 sequence-specific DNA binding K07726 - - 0.000000000000000000000000001502 114.0
MMD2_k127_235888_47 SnoaL-like domain - - - 0.0000000000000000000000001148 122.0
MMD2_k127_235888_48 stress protein (general stress protein 26) - - - 0.0000000000000000000000003757 113.0
MMD2_k127_235888_49 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000002609 105.0
MMD2_k127_235888_5 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 615.0
MMD2_k127_235888_50 Putative transposase - - - 0.00000000000000000000008388 105.0
MMD2_k127_235888_51 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000002356 107.0
MMD2_k127_235888_52 - - - - 0.000000000000000000004594 106.0
MMD2_k127_235888_53 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000001815 93.0
MMD2_k127_235888_54 - - - - 0.0000000001487 70.0
MMD2_k127_235888_55 - - - - 0.000000005776 64.0
MMD2_k127_235888_56 Protein of unknown function (DUF493) - - - 0.00000004695 65.0
MMD2_k127_235888_57 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000001116 53.0
MMD2_k127_235888_58 recombinase activity - - - 0.000001175 55.0
MMD2_k127_235888_6 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 567.0
MMD2_k127_235888_60 - - - - 0.00005825 53.0
MMD2_k127_235888_7 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 572.0
MMD2_k127_235888_8 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 580.0
MMD2_k127_235888_9 COG0793 Periplasmic protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 539.0
MMD2_k127_2365683_0 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 556.0
MMD2_k127_2365683_1 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 534.0
MMD2_k127_2365683_10 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000005722 218.0
MMD2_k127_2365683_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000005233 188.0
MMD2_k127_2365683_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000001462 175.0
MMD2_k127_2365683_13 - - - - 0.0000000000000000000000000000000000000000002882 169.0
MMD2_k127_2365683_14 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000003858 173.0
MMD2_k127_2365683_15 Zn-dependent - - - 0.0000000000000000000000000000000000002303 152.0
MMD2_k127_2365683_16 Protein of unknown function, DUF481 K07283 - - 0.000000000000000000000000000000002813 139.0
MMD2_k127_2365683_17 - - - - 0.000000000000000000000000002132 124.0
MMD2_k127_2365683_18 - - - - 0.000000000000000000000000002947 121.0
MMD2_k127_2365683_19 - - - - 0.000000000000000001512 91.0
MMD2_k127_2365683_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 482.0
MMD2_k127_2365683_20 - - - - 0.0000000000000000183 94.0
MMD2_k127_2365683_21 Amino acid permease K03294 - - 0.0000000000001994 72.0
MMD2_k127_2365683_22 Amino acid permease K03294 - - 0.0002209 47.0
MMD2_k127_2365683_3 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 432.0
MMD2_k127_2365683_4 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 363.0
MMD2_k127_2365683_5 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 351.0
MMD2_k127_2365683_6 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 305.0
MMD2_k127_2365683_7 DNA topological change - - - 0.00000000000000000000000000000000000000000000000000000000000001165 232.0
MMD2_k127_2365683_8 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000001241 216.0
MMD2_k127_2365683_9 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000002249 222.0
MMD2_k127_2393783_0 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 445.0
MMD2_k127_2393783_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 411.0
MMD2_k127_2393783_2 peptidase - - - 0.0000000000000000000000000000000000000000000000001928 188.0
MMD2_k127_2393783_3 - - - - 0.00000000000000000000000003088 119.0
MMD2_k127_2393783_5 - - - - 0.00000000000001206 86.0
MMD2_k127_2393783_6 Putative transposase - - - 0.00000000000323 76.0
MMD2_k127_2393783_7 - - - - 0.00000000001765 70.0
MMD2_k127_2393783_9 Putative transposase - - - 0.000000004486 61.0
MMD2_k127_2419662_0 Molecular chaperone. Has ATPase activity K04079 - - 1.242e-225 715.0
MMD2_k127_2419662_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 592.0
MMD2_k127_2419662_2 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000155 245.0
MMD2_k127_2419662_3 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000001558 176.0
MMD2_k127_2419662_4 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000001886 141.0
MMD2_k127_2419662_5 Domain of unknown function (DUF4426) - - - 0.0000000000000000000000000000001036 131.0
MMD2_k127_2419662_6 protein conserved in bacteria - - - 0.00000000000000000000007794 108.0
MMD2_k127_2427166_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 9.9e-229 731.0
MMD2_k127_2427166_1 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 440.0
MMD2_k127_2427166_10 Belongs to the DnaA family. HdA subfamily K10763 - - 0.00000000000000001368 86.0
MMD2_k127_2427166_2 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 284.0
MMD2_k127_2427166_3 Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 280.0
MMD2_k127_2427166_4 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000002172 244.0
MMD2_k127_2427166_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000003639 258.0
MMD2_k127_2427166_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000943 233.0
MMD2_k127_2427166_7 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000000000000000000867 194.0
MMD2_k127_2427166_8 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000002575 179.0
MMD2_k127_2427166_9 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000000000115 103.0
MMD2_k127_2432285_0 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001682 257.0
MMD2_k127_2432285_1 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000001771 202.0
MMD2_k127_2432285_2 - - - - 0.00000000000000000000000000000000000005923 156.0
MMD2_k127_2432285_3 Domain of unknown function (DUF4397) - - - 0.000000000000000000007237 107.0
MMD2_k127_2432285_4 endoribonuclease L-PSP - - - 0.00000000000000000006696 102.0
MMD2_k127_2432285_5 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000002223 97.0
MMD2_k127_2432285_6 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000006514 80.0
MMD2_k127_2432285_7 - - - - 0.000000000000007136 74.0
MMD2_k127_2432285_8 allantoin biosynthetic process - - - 0.00003796 55.0
MMD2_k127_2450673_0 DNA polymerase X family K02347 - - 5.654e-238 752.0
MMD2_k127_2450673_1 ABC transporter transmembrane region K06147,K11085 - - 1.258e-212 676.0
MMD2_k127_2450673_10 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 386.0
MMD2_k127_2450673_11 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 313.0
MMD2_k127_2450673_12 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001159 277.0
MMD2_k127_2450673_13 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003048 281.0
MMD2_k127_2450673_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000002106 261.0
MMD2_k127_2450673_15 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000004852 240.0
MMD2_k127_2450673_16 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000000000008242 199.0
MMD2_k127_2450673_17 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000000003245 190.0
MMD2_k127_2450673_18 Lanthionine synthetase C family protein - - - 0.00000000000000000000000000000000000000000000000002248 191.0
MMD2_k127_2450673_19 NHL repeat - - - 0.0000000000000000000000000000000000000004456 152.0
MMD2_k127_2450673_2 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 1.463e-203 663.0
MMD2_k127_2450673_20 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000001281 135.0
MMD2_k127_2450673_21 - - - - 0.000000000000000000000000000008356 132.0
MMD2_k127_2450673_22 Cytochrome c K17760 - 1.1.9.1 0.0000000000006978 73.0
MMD2_k127_2450673_3 TonB dependent receptor K02014 - - 3.373e-201 659.0
MMD2_k127_2450673_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 589.0
MMD2_k127_2450673_5 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 503.0
MMD2_k127_2450673_6 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 480.0
MMD2_k127_2450673_7 metallo-beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 409.0
MMD2_k127_2450673_8 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 402.0
MMD2_k127_2450673_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 394.0
MMD2_k127_2455324_0 Belongs to the peptidase S16 family - - - 2.452e-251 801.0
MMD2_k127_2455324_1 - - - - 0.00000000000002526 75.0
MMD2_k127_2455324_2 - - - - 0.00000000002037 66.0
MMD2_k127_2455324_3 Patatin-like phospholipase K07001 - - 0.00006684 55.0
MMD2_k127_2466511_0 Citrate transporter - - - 2.207e-210 675.0
MMD2_k127_2466511_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 308.0
MMD2_k127_2466511_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000355 226.0
MMD2_k127_2466511_3 - - - - 0.0000000000000000000002012 108.0
MMD2_k127_2466511_4 - - - - 0.00000000007725 76.0
MMD2_k127_2526915_0 Phage tail sheath C-terminal domain K06907 - - 2.513e-213 673.0
MMD2_k127_2526915_1 Protein of unknown function (DUF1593) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 492.0
MMD2_k127_2526915_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 363.0
MMD2_k127_2526915_3 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 337.0
MMD2_k127_2526915_4 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000006561 141.0
MMD2_k127_2526915_5 - - - - 0.000000000000000000000000000000166 144.0
MMD2_k127_2526915_6 - - - - 0.000000000000000001246 97.0
MMD2_k127_2526915_7 - - - - 0.000000000000004552 83.0
MMD2_k127_2526915_8 - - - - 0.0000026 52.0
MMD2_k127_2569894_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 597.0
MMD2_k127_2569894_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 460.0
MMD2_k127_2569894_2 Serine threonine protein kinase involved in cell cycle control - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 355.0
MMD2_k127_2569894_3 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 327.0
MMD2_k127_2569894_4 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000000000038 176.0
MMD2_k127_2569894_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000001345 160.0
MMD2_k127_2569894_6 - - - - 0.00000000000003816 85.0
MMD2_k127_2569894_7 - - - - 0.00000000000009419 82.0
MMD2_k127_2569894_8 - - - - 0.00000000004227 74.0
MMD2_k127_2587703_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 3.276e-237 749.0
MMD2_k127_2587703_1 SMART Elongator protein 3 MiaB NifB - - - 7.841e-223 701.0
MMD2_k127_2587703_10 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000001085 186.0
MMD2_k127_2587703_11 MmgE/PrpD family - - - 0.00000000000000000000000000000001046 146.0
MMD2_k127_2587703_12 - - - - 0.000000000000000000000000008912 113.0
MMD2_k127_2587703_13 Protein of unknown function (DUF2892) - - - 0.000000000000000000000104 107.0
MMD2_k127_2587703_14 Polymer-forming cytoskeletal - - - 0.000000000000000000000316 104.0
MMD2_k127_2587703_15 - - - - 0.000000000000000000003294 98.0
MMD2_k127_2587703_17 Polymer-forming cytoskeletal - - - 0.00000000000000009208 88.0
MMD2_k127_2587703_2 TrkA-N domain K11745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 614.0
MMD2_k127_2587703_4 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 314.0
MMD2_k127_2587703_5 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007258 263.0
MMD2_k127_2587703_6 Sugar (and other) transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000485 261.0
MMD2_k127_2587703_7 PFAM Cold-shock protein, DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000139 226.0
MMD2_k127_2587703_8 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000002313 228.0
MMD2_k127_2587703_9 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000004757 213.0
MMD2_k127_260130_0 Belongs to the Orn Lys Arg decarboxylase class-II family K00928,K12526 - 2.7.2.4,4.1.1.20 2.989e-291 918.0
MMD2_k127_260130_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.101e-250 785.0
MMD2_k127_260130_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 366.0
MMD2_k127_260130_3 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 346.0
MMD2_k127_260130_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
MMD2_k127_260130_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000001178 231.0
MMD2_k127_260130_6 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000002486 159.0
MMD2_k127_260130_7 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000138 91.0
MMD2_k127_2637466_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.179e-260 818.0
MMD2_k127_2637466_1 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 347.0
MMD2_k127_2637466_2 Flavodoxin-like fold K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001526 275.0
MMD2_k127_2685683_0 ABC transporter K06147,K18893 - - 1.622e-243 780.0
MMD2_k127_2685683_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 595.0
MMD2_k127_2685683_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 387.0
MMD2_k127_2685683_11 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 342.0
MMD2_k127_2685683_12 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 286.0
MMD2_k127_2685683_13 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
MMD2_k127_2685683_14 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000005539 274.0
MMD2_k127_2685683_15 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001397 276.0
MMD2_k127_2685683_16 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001688 250.0
MMD2_k127_2685683_17 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000006188 223.0
MMD2_k127_2685683_18 lactoylglutathione lyase activity K03088 - - 0.000000000000000000000000000000000000000000000000000000009218 210.0
MMD2_k127_2685683_19 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.000000000000000001951 87.0
MMD2_k127_2685683_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 562.0
MMD2_k127_2685683_20 - - - - 0.0000000000000008445 79.0
MMD2_k127_2685683_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 457.0
MMD2_k127_2685683_4 cystathione gamma lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 450.0
MMD2_k127_2685683_5 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 449.0
MMD2_k127_2685683_6 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 426.0
MMD2_k127_2685683_7 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 430.0
MMD2_k127_2685683_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 426.0
MMD2_k127_2685683_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 400.0
MMD2_k127_2689883_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1427.0
MMD2_k127_2689883_1 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 352.0
MMD2_k127_2689883_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000007247 196.0
MMD2_k127_2689883_3 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000001472 187.0
MMD2_k127_2689883_4 Transcriptional regulator - - - 0.0000000000000000007096 93.0
MMD2_k127_2689883_5 - - - - 0.00000000001753 70.0
MMD2_k127_270084_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.569e-261 815.0
MMD2_k127_270084_1 TonB-dependent receptor - - - 8.241e-255 805.0
MMD2_k127_270084_10 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 515.0
MMD2_k127_270084_11 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 499.0
MMD2_k127_270084_12 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 461.0
MMD2_k127_270084_13 Dak1 domain K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 467.0
MMD2_k127_270084_14 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 461.0
MMD2_k127_270084_15 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 409.0
MMD2_k127_270084_16 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 353.0
MMD2_k127_270084_17 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 336.0
MMD2_k127_270084_18 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 339.0
MMD2_k127_270084_19 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 324.0
MMD2_k127_270084_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 5.77e-222 699.0
MMD2_k127_270084_20 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 309.0
MMD2_k127_270084_21 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 310.0
MMD2_k127_270084_22 in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 295.0
MMD2_k127_270084_23 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002954 286.0
MMD2_k127_270084_24 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003525 299.0
MMD2_k127_270084_25 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001228 291.0
MMD2_k127_270084_26 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002286 262.0
MMD2_k127_270084_27 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003583 265.0
MMD2_k127_270084_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
MMD2_k127_270084_29 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001889 252.0
MMD2_k127_270084_3 PQQ enzyme repeat K00117 - 1.1.5.2 5.261e-209 672.0
MMD2_k127_270084_30 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002355 236.0
MMD2_k127_270084_31 Gluconate 2-dehydrogenase subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000538 222.0
MMD2_k127_270084_32 Dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000001413 206.0
MMD2_k127_270084_33 - - - - 0.00000000000000000000000000000000000000000004681 175.0
MMD2_k127_270084_34 Arylesterase - - - 0.0000000000000000000000000000000000000000003172 171.0
MMD2_k127_270084_35 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000001372 172.0
MMD2_k127_270084_36 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000003289 160.0
MMD2_k127_270084_38 - - - - 0.000000000000000000000000000000000000002324 164.0
MMD2_k127_270084_39 - - - - 0.000000000000000000000000000000000000002748 166.0
MMD2_k127_270084_4 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 644.0
MMD2_k127_270084_40 - - - - 0.0000000000000000000000000000000000002249 146.0
MMD2_k127_270084_41 Kef-type K transport systems - - - 0.0000000000000000000000000000000000004155 145.0
MMD2_k127_270084_42 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000002024 151.0
MMD2_k127_270084_43 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000003694 147.0
MMD2_k127_270084_44 DoxX-like family - - - 0.00000000000000000000000000000000004595 139.0
MMD2_k127_270084_45 - - - - 0.00000000000000000000000000000003774 133.0
MMD2_k127_270084_46 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000006185 132.0
MMD2_k127_270084_47 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000000000111 103.0
MMD2_k127_270084_48 - - - - 0.00000000000000000009854 94.0
MMD2_k127_270084_49 FixH K09926 - - 0.00000000000009466 85.0
MMD2_k127_270084_5 TIGRFAM cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 595.0
MMD2_k127_270084_50 - - - - 0.0000000000001536 82.0
MMD2_k127_270084_51 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000000000009104 69.0
MMD2_k127_270084_52 - - - - 0.000000000001931 72.0
MMD2_k127_270084_54 SnoaL-like domain - - - 0.00000000001053 73.0
MMD2_k127_270084_55 diguanylate cyclase - - - 0.0000000001747 74.0
MMD2_k127_270084_56 Cytochrome oxidase maturation protein - - - 0.0000000002075 73.0
MMD2_k127_270084_57 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000001122 54.0
MMD2_k127_270084_58 - - - - 0.0000009638 58.0
MMD2_k127_270084_59 - - - - 0.0009658 51.0
MMD2_k127_270084_6 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 624.0
MMD2_k127_270084_7 PQQ-like domain K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 600.0
MMD2_k127_270084_8 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 571.0
MMD2_k127_270084_9 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 557.0
MMD2_k127_2726551_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.461e-316 986.0
MMD2_k127_2726551_1 Acetolactate synthase K01652 - 2.2.1.6 3.895e-281 877.0
MMD2_k127_2726551_10 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 412.0
MMD2_k127_2726551_11 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 294.0
MMD2_k127_2726551_12 Secreted protein, containing von Willebrand factor (VWF) type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001239 293.0
MMD2_k127_2726551_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000343 263.0
MMD2_k127_2726551_14 COG0811 Biopolymer transport proteins - - - 0.0000000000000000000000000000000000000000000000000000000000001045 221.0
MMD2_k127_2726551_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001815 213.0
MMD2_k127_2726551_16 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.000000000000000000000000000000000000000000000007837 186.0
MMD2_k127_2726551_17 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000002735 172.0
MMD2_k127_2726551_18 Domain of unknown function (DUF4399) - - - 0.00000000000000000000000000000000000000000003951 166.0
MMD2_k127_2726551_19 Peptidase family M23 - - - 0.000000000000000000000000000000000001966 147.0
MMD2_k127_2726551_2 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 6.546e-272 851.0
MMD2_k127_2726551_20 - - - - 0.0000000000000000000000000000000018 147.0
MMD2_k127_2726551_21 NlpC/P60 family - - - 0.000000000000000000000000000002204 132.0
MMD2_k127_2726551_22 CHRD domain - - - 0.000000000000000000000000000007599 126.0
MMD2_k127_2726551_23 Family of unknown function (DUF5329) - - - 0.00000000000000000000000000004098 121.0
MMD2_k127_2726551_24 - - - - 0.0000000000000000000000002177 108.0
MMD2_k127_2726551_25 Putative transposase - - - 0.000000000000000008443 84.0
MMD2_k127_2726551_26 OmpA family - - - 0.000000000000000008678 93.0
MMD2_k127_2726551_27 belongs to the protein kinase superfamily K20716 - - 0.0000000000000008625 89.0
MMD2_k127_2726551_28 lactoylglutathione lyase activity - - - 0.000000000000005922 79.0
MMD2_k127_2726551_29 heme binding K06194,K06401,K21472,K21473 - - 0.0000000007658 61.0
MMD2_k127_2726551_3 COG1109 Phosphomannomutase K01840,K15778 - 5.4.2.2,5.4.2.8 5.83e-200 639.0
MMD2_k127_2726551_30 Putative transposase - - - 0.0003037 48.0
MMD2_k127_2726551_31 (FHA) domain - - - 0.0003548 53.0
MMD2_k127_2726551_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 534.0
MMD2_k127_2726551_5 Aminotransferase class-III K00822,K00833 - 2.6.1.18,2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 530.0
MMD2_k127_2726551_6 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 499.0
MMD2_k127_2726551_7 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 524.0
MMD2_k127_2726551_8 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 451.0
MMD2_k127_2726551_9 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 448.0
MMD2_k127_2786593_0 Dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 502.0
MMD2_k127_2786593_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 382.0
MMD2_k127_2786593_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000334 236.0
MMD2_k127_2786593_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000003143 197.0
MMD2_k127_280662_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1290.0
MMD2_k127_280662_1 XRE family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
MMD2_k127_280662_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006553 284.0
MMD2_k127_280662_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003415 256.0
MMD2_k127_280662_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000009026 199.0
MMD2_k127_280662_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000001968 171.0
MMD2_k127_3027543_0 Peptidase family M41 K03798 - - 1.121e-231 732.0
MMD2_k127_3027543_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 1.449e-201 648.0
MMD2_k127_3027543_10 Transcriptional regulator - - - 0.00000000000000000000000000000002482 138.0
MMD2_k127_3027543_11 - - - - 0.0000000000000000000000000000002083 137.0
MMD2_k127_3027543_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000001799 118.0
MMD2_k127_3027543_13 Protein of unknown function (DUF504) - - - 0.000000000000000000000001347 112.0
MMD2_k127_3027543_14 ligase activity K01474 - 3.5.2.14 0.00000000000000000000000826 117.0
MMD2_k127_3027543_15 Acid phosphatase homologues - - - 0.000000000000000001224 98.0
MMD2_k127_3027543_16 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 0.0000001901 64.0
MMD2_k127_3027543_17 LysR substrate binding domain - - - 0.0000003075 52.0
MMD2_k127_3027543_18 - - - - 0.0009606 50.0
MMD2_k127_3027543_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 561.0
MMD2_k127_3027543_3 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 569.0
MMD2_k127_3027543_4 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 511.0
MMD2_k127_3027543_5 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 302.0
MMD2_k127_3027543_6 PFAM isochorismatase hydrolase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 286.0
MMD2_k127_3027543_7 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000008107 212.0
MMD2_k127_3027543_8 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000002606 212.0
MMD2_k127_3027543_9 Belongs to the peptidase M24B family K01262,K01271,K08688,K15783 - 3.4.11.9,3.4.13.9,3.5.3.3,3.5.4.44 0.0000000000000000000000000000000000000000000000373 185.0
MMD2_k127_3084186_0 homoserine dehydrogenase - - - 5.287e-215 675.0
MMD2_k127_3084186_1 amine oxidase K01854 - 5.4.99.9 1.569e-205 647.0
MMD2_k127_3084186_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003347 231.0
MMD2_k127_3084186_11 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000003164 223.0
MMD2_k127_3084186_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000002285 151.0
MMD2_k127_3084186_13 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000001348 137.0
MMD2_k127_3084186_14 - - - - 0.00000000000003256 85.0
MMD2_k127_3084186_15 - - - - 0.000000000006586 66.0
MMD2_k127_3084186_16 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000003097 67.0
MMD2_k127_3084186_17 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000003307 54.0
MMD2_k127_3084186_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 587.0
MMD2_k127_3084186_3 Polysaccharide biosynthesis protein K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 469.0
MMD2_k127_3084186_4 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 434.0
MMD2_k127_3084186_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 362.0
MMD2_k127_3084186_6 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 376.0
MMD2_k127_3084186_7 Glucose-1-phosphate cytidylyltransferase K00978,K15669 - 2.7.7.33,2.7.7.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 331.0
MMD2_k127_3084186_8 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002549 275.0
MMD2_k127_3084186_9 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000003749 258.0
MMD2_k127_3139999_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1270.0
MMD2_k127_3139999_1 MacB-like periplasmic core domain - - - 1.217e-317 993.0
MMD2_k127_3139999_10 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 359.0
MMD2_k127_3139999_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 355.0
MMD2_k127_3139999_12 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 355.0
MMD2_k127_3139999_13 Prolyl oligopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 373.0
MMD2_k127_3139999_14 Chromate resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 291.0
MMD2_k127_3139999_15 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005708 280.0
MMD2_k127_3139999_16 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008171 265.0
MMD2_k127_3139999_17 PFAM UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000006021 267.0
MMD2_k127_3139999_18 cellular water homeostasis K03442,K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005452 252.0
MMD2_k127_3139999_19 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004672 259.0
MMD2_k127_3139999_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 2.766e-299 947.0
MMD2_k127_3139999_20 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000008965 244.0
MMD2_k127_3139999_21 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000169 217.0
MMD2_k127_3139999_22 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000009659 209.0
MMD2_k127_3139999_23 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000002661 199.0
MMD2_k127_3139999_24 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000003941 209.0
MMD2_k127_3139999_25 - - - - 0.0000000000000000000000000000000000000003318 162.0
MMD2_k127_3139999_26 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000002297 156.0
MMD2_k127_3139999_27 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000287 135.0
MMD2_k127_3139999_28 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000001101 124.0
MMD2_k127_3139999_29 Protein of unknown function (DUF2892) - - - 0.00000000000000000000783 93.0
MMD2_k127_3139999_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 561.0
MMD2_k127_3139999_30 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000007664 92.0
MMD2_k127_3139999_31 Domain of unknown function (DUF4149) - - - 0.000000000000002996 82.0
MMD2_k127_3139999_33 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000001709 77.0
MMD2_k127_3139999_34 SnoaL-like domain - - - 0.000009837 57.0
MMD2_k127_3139999_35 AMP binding - - - 0.00009693 53.0
MMD2_k127_3139999_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 481.0
MMD2_k127_3139999_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 490.0
MMD2_k127_3139999_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 451.0
MMD2_k127_3139999_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 454.0
MMD2_k127_3139999_8 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 407.0
MMD2_k127_3139999_9 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 384.0
MMD2_k127_3154088_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1225.0
MMD2_k127_3154088_1 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 504.0
MMD2_k127_3154088_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000001192 211.0
MMD2_k127_3154088_11 DSBA-like thioredoxin domain K07396 - - 0.000000000000000000000000000000000000000000000000002677 191.0
MMD2_k127_3154088_12 Putative adhesin - - - 0.00000000000000000000000000000000002167 151.0
MMD2_k127_3154088_13 hydrolase (HAD superfamily) K07025 - - 0.00000000000000000000000000000001827 140.0
MMD2_k127_3154088_14 domain, Protein - - - 0.0000000000000000000000000004499 132.0
MMD2_k127_3154088_16 Para-aminobenzoate synthase component K01665 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 0.0000004144 53.0
MMD2_k127_3154088_17 OmpA-like transmembrane domain - - - 0.000002092 58.0
MMD2_k127_3154088_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 412.0
MMD2_k127_3154088_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 359.0
MMD2_k127_3154088_4 Methionine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 316.0
MMD2_k127_3154088_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001046 276.0
MMD2_k127_3154088_6 Belongs to the HpcH HpaI aldolase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
MMD2_k127_3154088_7 PFAM lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 267.0
MMD2_k127_3154088_8 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000006532 222.0
MMD2_k127_3154088_9 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.000000000000000000000000000000000000000000000000000000000001747 228.0
MMD2_k127_3154470_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 5.414e-308 958.0
MMD2_k127_3154470_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.116e-258 805.0
MMD2_k127_3154470_10 peptidase K06194 - - 0.0000000000000000000000000000000000000000000005799 184.0
MMD2_k127_3154470_11 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000001005 151.0
MMD2_k127_3154470_12 succinate dehydrogenase - - - 0.0000000000000000000000000000002184 127.0
MMD2_k127_3154470_13 succinate dehydrogenase K00241 - - 0.0000000000000000000000000001775 118.0
MMD2_k127_3154470_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000003003 88.0
MMD2_k127_3154470_15 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000001304 79.0
MMD2_k127_3154470_16 Protein of unknown function (DUF1674) - - - 0.0000004594 62.0
MMD2_k127_3154470_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 586.0
MMD2_k127_3154470_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 589.0
MMD2_k127_3154470_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 506.0
MMD2_k127_3154470_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 458.0
MMD2_k127_3154470_6 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 407.0
MMD2_k127_3154470_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 334.0
MMD2_k127_3154470_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000005071 276.0
MMD2_k127_3154470_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000004058 263.0
MMD2_k127_3169201_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 597.0
MMD2_k127_3169201_1 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 529.0
MMD2_k127_3169201_10 - - - - 0.0000007096 59.0
MMD2_k127_3169201_11 SnoaL-like domain - - - 0.0003508 50.0
MMD2_k127_3169201_2 Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 405.0
MMD2_k127_3169201_3 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001132 263.0
MMD2_k127_3169201_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005093 269.0
MMD2_k127_3169201_5 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000001087 237.0
MMD2_k127_3169201_6 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000006818 229.0
MMD2_k127_3169201_7 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000004962 207.0
MMD2_k127_3169201_8 - - - - 0.0000000000000000000000000000000000000000000000000005998 207.0
MMD2_k127_3178383_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.845e-267 831.0
MMD2_k127_3178383_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 2.094e-233 731.0
MMD2_k127_3178383_10 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000136 242.0
MMD2_k127_3178383_11 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000001133 231.0
MMD2_k127_3178383_12 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000008927 191.0
MMD2_k127_3178383_13 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000000000000000000000000000000004585 187.0
MMD2_k127_3178383_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000000000000003565 172.0
MMD2_k127_3178383_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000005833 158.0
MMD2_k127_3178383_16 protein involved in tolerance to divalent cations K03926 - - 0.0000000000000000000000000002657 119.0
MMD2_k127_3178383_17 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000006706 113.0
MMD2_k127_3178383_18 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.00000000000000000001106 95.0
MMD2_k127_3178383_19 protein conserved in bacteria - - - 0.00000000000000000002306 93.0
MMD2_k127_3178383_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.868e-227 738.0
MMD2_k127_3178383_20 Protein of unknown function (DUF3426) - - - 0.00000000000000003327 93.0
MMD2_k127_3178383_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 606.0
MMD2_k127_3178383_4 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 608.0
MMD2_k127_3178383_5 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 541.0
MMD2_k127_3178383_6 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 399.0
MMD2_k127_3178383_7 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 377.0
MMD2_k127_3178383_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 366.0
MMD2_k127_3178383_9 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000003326 261.0
MMD2_k127_3186307_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 465.0
MMD2_k127_3186307_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 387.0
MMD2_k127_3186307_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 323.0
MMD2_k127_3186307_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 303.0
MMD2_k127_3186307_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000502 217.0
MMD2_k127_3186307_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000002081 204.0
MMD2_k127_3186307_6 Riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000045 204.0
MMD2_k127_3186307_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000001254 150.0
MMD2_k127_3186307_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000226 130.0
MMD2_k127_3186307_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000000000000001047 88.0
MMD2_k127_3280898_0 Heat shock 70 kDa protein K04043 - - 9e-323 997.0
MMD2_k127_3280898_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 517.0
MMD2_k127_3280898_10 serine threonine protein kinase - - - 0.0000000000000000000000006944 106.0
MMD2_k127_3280898_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000002703 97.0
MMD2_k127_3280898_12 - - - - 0.0000926 49.0
MMD2_k127_3280898_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 477.0
MMD2_k127_3280898_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 366.0
MMD2_k127_3280898_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 346.0
MMD2_k127_3280898_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000001213 249.0
MMD2_k127_3280898_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000001749 206.0
MMD2_k127_3280898_7 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000001429 197.0
MMD2_k127_3280898_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000001757 138.0
MMD2_k127_3280898_9 Cyclase dehydrase - - - 0.000000000000000000000000000000008364 140.0
MMD2_k127_3323841_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1518.0
MMD2_k127_3323841_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1034.0
MMD2_k127_3323841_10 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 349.0
MMD2_k127_3323841_11 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 319.0
MMD2_k127_3323841_12 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002232 282.0
MMD2_k127_3323841_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000001298 237.0
MMD2_k127_3323841_14 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000002819 228.0
MMD2_k127_3323841_15 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000001152 211.0
MMD2_k127_3323841_16 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.0000000000000000000000000000000000000000000000000000000002085 207.0
MMD2_k127_3323841_17 GHMP kinases N terminal domain K00938 - 2.7.4.2 0.0000000000000000000000000000000000000000000004104 179.0
MMD2_k127_3323841_18 DUF218 domain - - - 0.000000000000000000000000000000000000000004986 165.0
MMD2_k127_3323841_19 - - - - 0.0000000000000000000000001071 114.0
MMD2_k127_3323841_2 Hydroxymethylglutaryl-coenzyme A reductase K00054 - 1.1.1.88 4.487e-319 994.0
MMD2_k127_3323841_20 MlaC protein K07323 - - 0.000000000000000000000009213 109.0
MMD2_k127_3323841_21 other phosphorylase family 1 K01243 - 3.2.2.9 0.000000000000000005054 94.0
MMD2_k127_3323841_22 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.00000001073 60.0
MMD2_k127_3323841_3 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124 - - 3.278e-238 746.0
MMD2_k127_3323841_4 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 593.0
MMD2_k127_3323841_5 synthase K01641,K15311 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 526.0
MMD2_k127_3323841_6 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 392.0
MMD2_k127_3323841_7 Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 386.0
MMD2_k127_3323841_8 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 376.0
MMD2_k127_3323841_9 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 352.0
MMD2_k127_3427375_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1257.0
MMD2_k127_3427375_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.138e-254 810.0
MMD2_k127_3427375_10 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 376.0
MMD2_k127_3427375_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 375.0
MMD2_k127_3427375_12 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 338.0
MMD2_k127_3427375_13 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 347.0
MMD2_k127_3427375_14 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 327.0
MMD2_k127_3427375_15 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002911 274.0
MMD2_k127_3427375_16 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000004145 244.0
MMD2_k127_3427375_17 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000007702 218.0
MMD2_k127_3427375_18 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000002235 208.0
MMD2_k127_3427375_19 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000003094 190.0
MMD2_k127_3427375_2 Protein tyrosine kinase - - - 1.788e-218 705.0
MMD2_k127_3427375_20 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000563 160.0
MMD2_k127_3427375_21 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000009351 164.0
MMD2_k127_3427375_22 Methyltransferase - - - 0.000000000000000000000000000000000000003238 156.0
MMD2_k127_3427375_23 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000001233 152.0
MMD2_k127_3427375_24 Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000007718 123.0
MMD2_k127_3427375_25 protein conserved in bacteria K09938 - - 0.00000000000000000000000002987 126.0
MMD2_k127_3427375_26 Protein of unknown function (DUF3108) - - - 0.00000000000003998 81.0
MMD2_k127_3427375_27 ubiE/COQ5 methyltransferase family - - - 0.000000000001145 74.0
MMD2_k127_3427375_3 PFAM biotin lipoyl attachment domain-containing protein K00382 - 1.8.1.4 2.659e-218 709.0
MMD2_k127_3427375_4 PFAM Type II secretion system protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 525.0
MMD2_k127_3427375_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 512.0
MMD2_k127_3427375_6 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 424.0
MMD2_k127_3427375_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 417.0
MMD2_k127_3427375_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 407.0
MMD2_k127_3427375_9 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 393.0
MMD2_k127_3473376_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2235.0
MMD2_k127_3473376_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1015.0
MMD2_k127_3473376_10 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 377.0
MMD2_k127_3473376_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 366.0
MMD2_k127_3473376_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 334.0
MMD2_k127_3473376_13 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 325.0
MMD2_k127_3473376_14 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 330.0
MMD2_k127_3473376_15 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 322.0
MMD2_k127_3473376_16 PFAM AsmA family protein K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 327.0
MMD2_k127_3473376_17 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 304.0
MMD2_k127_3473376_18 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07663 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 297.0
MMD2_k127_3473376_19 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 299.0
MMD2_k127_3473376_2 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 1.017e-240 751.0
MMD2_k127_3473376_20 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 293.0
MMD2_k127_3473376_21 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 300.0
MMD2_k127_3473376_22 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001128 293.0
MMD2_k127_3473376_23 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003084 277.0
MMD2_k127_3473376_24 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003215 264.0
MMD2_k127_3473376_25 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000004816 259.0
MMD2_k127_3473376_26 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000452 253.0
MMD2_k127_3473376_27 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009126 253.0
MMD2_k127_3473376_28 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000001027 240.0
MMD2_k127_3473376_29 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000465 231.0
MMD2_k127_3473376_3 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 572.0
MMD2_k127_3473376_30 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000008566 221.0
MMD2_k127_3473376_31 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000005113 209.0
MMD2_k127_3473376_32 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 0.000000000000000000000000000000000000000039 159.0
MMD2_k127_3473376_33 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000004251 140.0
MMD2_k127_3473376_34 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000004233 132.0
MMD2_k127_3473376_35 methyltransferase activity - - - 0.0000000000000000000000000000005418 128.0
MMD2_k127_3473376_36 Domain of unknown function (DUF4124) - - - 0.00000000000000000001955 100.0
MMD2_k127_3473376_37 there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc K02913 - - 0.0000000000000000001688 88.0
MMD2_k127_3473376_38 Late embryogenesis abundant protein - - - 0.000000006148 63.0
MMD2_k127_3473376_4 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 542.0
MMD2_k127_3473376_40 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00001818 50.0
MMD2_k127_3473376_5 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 522.0
MMD2_k127_3473376_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 458.0
MMD2_k127_3473376_7 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 428.0
MMD2_k127_3473376_8 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 392.0
MMD2_k127_3473376_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 400.0
MMD2_k127_349699_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.199e-289 904.0
MMD2_k127_349699_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 592.0
MMD2_k127_349699_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000002513 218.0
MMD2_k127_349699_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000326 220.0
MMD2_k127_349699_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000001883 82.0
MMD2_k127_3592477_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 3.244e-210 664.0
MMD2_k127_3592477_1 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 527.0
MMD2_k127_3592477_10 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 328.0
MMD2_k127_3592477_11 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002883 289.0
MMD2_k127_3592477_12 Protein of unknown function (DUF1415) K09941 - - 0.00000000000000000000000000000000000000000000000000000000001613 213.0
MMD2_k127_3592477_13 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000009854 181.0
MMD2_k127_3592477_14 - - - - 0.0000000000000000000000000000000000000005412 156.0
MMD2_k127_3592477_15 - - - - 0.000000000000000000000000000000000000005928 153.0
MMD2_k127_3592477_16 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000003549 138.0
MMD2_k127_3592477_17 Transglutaminase/protease-like homologues - - - 0.00000000000000000000001019 110.0
MMD2_k127_3592477_18 Protein of unknown function (DUF2845) - - - 0.000000000000008522 78.0
MMD2_k127_3592477_2 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 495.0
MMD2_k127_3592477_20 - - - - 0.00000000006023 67.0
MMD2_k127_3592477_21 Protein of unknown function (DUF3617) - - - 0.0000000001271 67.0
MMD2_k127_3592477_22 Polymer-forming cytoskeletal - - - 0.0001752 49.0
MMD2_k127_3592477_3 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 493.0
MMD2_k127_3592477_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 447.0
MMD2_k127_3592477_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 428.0
MMD2_k127_3592477_6 sensor diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 444.0
MMD2_k127_3592477_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 404.0
MMD2_k127_3592477_8 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 381.0
MMD2_k127_3592477_9 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 347.0
MMD2_k127_35970_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 4.37e-283 889.0
MMD2_k127_35970_1 efflux transmembrane transporter activity - - - 2.406e-270 858.0
MMD2_k127_35970_10 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 382.0
MMD2_k127_35970_11 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 385.0
MMD2_k127_35970_12 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 327.0
MMD2_k127_35970_13 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 325.0
MMD2_k127_35970_14 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 320.0
MMD2_k127_35970_15 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 312.0
MMD2_k127_35970_16 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002455 263.0
MMD2_k127_35970_17 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
MMD2_k127_35970_18 Co Zn Cd efflux system component - - - 0.000000000000000000000000000000000000000000000000000000000000000000008323 243.0
MMD2_k127_35970_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001331 243.0
MMD2_k127_35970_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 1.473e-259 816.0
MMD2_k127_35970_20 Class II aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000131 228.0
MMD2_k127_35970_21 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000009251 223.0
MMD2_k127_35970_22 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000004211 223.0
MMD2_k127_35970_23 protein serine/threonine phosphatase activity K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000003439 208.0
MMD2_k127_35970_24 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000000000005051 192.0
MMD2_k127_35970_25 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000008554 188.0
MMD2_k127_35970_27 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000001742 178.0
MMD2_k127_35970_28 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000002899 176.0
MMD2_k127_35970_29 conserved protein, contains FHA domain K11894,K11913 - - 0.000000000000000000000000000000000000000000005606 181.0
MMD2_k127_35970_3 xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 8.121e-218 702.0
MMD2_k127_35970_30 Predicted membrane protein (DUF2214) K08983 - - 0.0000000000000000000000000000000000000001574 158.0
MMD2_k127_35970_31 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000002483 158.0
MMD2_k127_35970_32 Domain of unknown function (DUF1820) - - - 0.000000000000000000000000000000000000002267 150.0
MMD2_k127_35970_33 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000002844 167.0
MMD2_k127_35970_34 Pfam Tetratricopeptide - - - 0.0000000000000000000000000000000001347 140.0
MMD2_k127_35970_35 May be involved in recombination K03554 - - 0.0000000000000000000000000000000001443 144.0
MMD2_k127_35970_36 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.000000000000000000000000000000003512 137.0
MMD2_k127_35970_37 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000002255 126.0
MMD2_k127_35970_38 YjbR - - - 0.0000000000000000000000009078 107.0
MMD2_k127_35970_4 Carboxypeptidase K14677 - 3.5.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 511.0
MMD2_k127_35970_40 Sigma-70, region 4 K03088 - - 0.0000000000233 76.0
MMD2_k127_35970_42 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000001009 62.0
MMD2_k127_35970_5 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 465.0
MMD2_k127_35970_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 454.0
MMD2_k127_35970_7 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 447.0
MMD2_k127_35970_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 429.0
MMD2_k127_35970_9 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 404.0
MMD2_k127_3645920_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 4.12e-243 766.0
MMD2_k127_3645920_1 Receptor - - - 6.357e-213 693.0
MMD2_k127_3645920_10 outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 377.0
MMD2_k127_3645920_11 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 330.0
MMD2_k127_3645920_12 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000159 262.0
MMD2_k127_3645920_13 Helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000001901 203.0
MMD2_k127_3645920_14 Water Stress and Hypersensitive response - - - 0.0000000000000000000000000000000000000000000001676 175.0
MMD2_k127_3645920_15 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000002127 164.0
MMD2_k127_3645920_16 Spore Coat Protein U domain - - - 0.000000000000000000001615 107.0
MMD2_k127_3645920_17 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000003129 97.0
MMD2_k127_3645920_18 Spore Coat Protein U domain - - - 0.00000000000000001574 89.0
MMD2_k127_3645920_19 COG3121 P pilus assembly protein, chaperone PapD K07346 - - 0.0000000000000001015 89.0
MMD2_k127_3645920_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 583.0
MMD2_k127_3645920_20 Protein of unknown function (DUF423) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000009608 83.0
MMD2_k127_3645920_21 - - - - 0.000005904 56.0
MMD2_k127_3645920_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 510.0
MMD2_k127_3645920_4 Sugar (and other) transporter K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 477.0
MMD2_k127_3645920_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 452.0
MMD2_k127_3645920_6 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 444.0
MMD2_k127_3645920_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 395.0
MMD2_k127_3645920_8 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 400.0
MMD2_k127_3645920_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 379.0
MMD2_k127_3699029_0 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 463.0
MMD2_k127_3706961_0 AAA domain - - - 7.003e-308 988.0
MMD2_k127_3706961_1 DNA topological change K03168 - 5.99.1.2 3.999e-215 696.0
MMD2_k127_3706961_10 Fe-S-cluster oxidoreductase K06940 - - 0.00000000000000000000000000000000000000000002288 167.0
MMD2_k127_3706961_11 MazG-like family - - - 0.0000000000000000000000000000000000000033 153.0
MMD2_k127_3706961_12 Alpha beta hydrolase fold-3 domain protein - - - 0.00000000000000000000000000000002985 132.0
MMD2_k127_3706961_13 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000009219 115.0
MMD2_k127_3706961_14 Domain of unknown function (DUF3368) - - - 0.00000000000000000007624 96.0
MMD2_k127_3706961_15 ankyrin repeat - - - 0.0000000000000000002503 103.0
MMD2_k127_3706961_16 RNA-binding - - - 0.000000000000000001257 90.0
MMD2_k127_3706961_17 - - - - 0.00000000000005943 83.0
MMD2_k127_3706961_18 Glycine zipper 2TM domain - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.0000000007464 67.0
MMD2_k127_3706961_19 30S ribosomal protein 2 K13126 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009651,GO:0009941,GO:0010029,GO:0010035,GO:0016020,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042221,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0047484,GO:0048519,GO:0048580,GO:0048583,GO:0048585,GO:0050789,GO:0050793,GO:0050896,GO:0051239,GO:0055035,GO:0065007,GO:0080134,GO:0080148,GO:0097159,GO:1900140,GO:1901000,GO:1901001,GO:1901363,GO:1901700,GO:2000026,GO:2000070 - 0.000000001039 63.0
MMD2_k127_3706961_2 LVIVD repeat - - - 9.818e-213 679.0
MMD2_k127_3706961_20 Carboxymuconolactone decarboxylase family - - - 0.00001286 55.0
MMD2_k127_3706961_21 DNA-binding transcription factor activity - - - 0.000417 49.0
MMD2_k127_3706961_3 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 572.0
MMD2_k127_3706961_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 385.0
MMD2_k127_3706961_6 Domain of unknown function(DUF2779) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 362.0
MMD2_k127_3706961_7 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 359.0
MMD2_k127_3706961_8 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 355.0
MMD2_k127_3706961_9 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 325.0
MMD2_k127_3733395_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 546.0
MMD2_k127_3733395_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 411.0
MMD2_k127_3733395_2 type I secretion outer membrane protein, TolC K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 303.0
MMD2_k127_3733395_3 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000007036 211.0
MMD2_k127_3733395_4 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000155 115.0
MMD2_k127_3775884_0 MMPL family - - - 0.0 1185.0
MMD2_k127_3775884_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 305.0
MMD2_k127_3775884_2 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000004899 228.0
MMD2_k127_3775884_3 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000048 219.0
MMD2_k127_3775884_4 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000002997 204.0
MMD2_k127_3775884_5 - - - - 0.0000000000000000000000000001235 126.0
MMD2_k127_3775884_6 - - - - 0.00000000000000000000000002343 113.0
MMD2_k127_3775884_7 - - - - 0.00000000000000000000000004096 117.0
MMD2_k127_3775884_8 - - - - 0.0000000000000000000002559 101.0
MMD2_k127_3775884_9 - - - - 0.0000032 51.0
MMD2_k127_3865509_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005372 245.0
MMD2_k127_3865509_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000005219 231.0
MMD2_k127_3865509_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000002089 198.0
MMD2_k127_3865509_3 - - - - 0.000000000000000000000000000006577 123.0
MMD2_k127_3865509_4 - - - - 0.000000000000000000000000001108 129.0
MMD2_k127_3865509_5 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000004887 113.0
MMD2_k127_3874877_0 Peptidase M16 - - - 8.108e-245 772.0
MMD2_k127_3874877_1 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 561.0
MMD2_k127_3874877_10 Two component transcriptional regulator, winged helix family K07662,K19610 GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010810,GO:0019219,GO:0019222,GO:0030155,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000006567 236.0
MMD2_k127_3874877_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000004115 202.0
MMD2_k127_3874877_12 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000001133 187.0
MMD2_k127_3874877_13 - - - - 0.000000005914 67.0
MMD2_k127_3874877_14 Bacterial SH3 domain homologues - - - 0.00002289 54.0
MMD2_k127_3874877_2 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 526.0
MMD2_k127_3874877_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 460.0
MMD2_k127_3874877_4 Transcriptional regulator K06714,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 445.0
MMD2_k127_3874877_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 415.0
MMD2_k127_3874877_6 DNA repair photolyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 404.0
MMD2_k127_3874877_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005977 275.0
MMD2_k127_3874877_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001213 253.0
MMD2_k127_3874877_9 Phospholipase/Carboxylesterase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000001804 259.0
MMD2_k127_3923483_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 7.277e-263 821.0
MMD2_k127_3923483_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 2.842e-199 647.0
MMD2_k127_3923483_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 456.0
MMD2_k127_3923483_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 442.0
MMD2_k127_3923483_12 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 392.0
MMD2_k127_3923483_13 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 338.0
MMD2_k127_3923483_14 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 329.0
MMD2_k127_3923483_15 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 325.0
MMD2_k127_3923483_16 polyphosphate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
MMD2_k127_3923483_17 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 293.0
MMD2_k127_3923483_18 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002806 283.0
MMD2_k127_3923483_19 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002306 267.0
MMD2_k127_3923483_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.563e-197 632.0
MMD2_k127_3923483_20 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002618 247.0
MMD2_k127_3923483_21 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000006199 239.0
MMD2_k127_3923483_22 Hydrolase - - - 0.00000000000000000000000000000000000000000004352 167.0
MMD2_k127_3923483_23 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000008825 182.0
MMD2_k127_3923483_24 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000001501 136.0
MMD2_k127_3923483_25 pfam rdd - - - 0.0000000000000000000000000000002043 129.0
MMD2_k127_3923483_26 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000002162 136.0
MMD2_k127_3923483_27 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000002455 109.0
MMD2_k127_3923483_28 mercury ion transmembrane transporter activity - - - 0.000000000000000000512 90.0
MMD2_k127_3923483_29 - - - - 0.00000000000000003173 86.0
MMD2_k127_3923483_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 564.0
MMD2_k127_3923483_31 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000002181 63.0
MMD2_k127_3923483_32 FeoA - - - 0.00000003692 57.0
MMD2_k127_3923483_33 Resolvase - - - 0.0006648 44.0
MMD2_k127_3923483_4 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 557.0
MMD2_k127_3923483_5 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 517.0
MMD2_k127_3923483_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 490.0
MMD2_k127_3923483_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 486.0
MMD2_k127_3923483_8 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 482.0
MMD2_k127_3923483_9 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 479.0
MMD2_k127_395091_0 - - - - 3.914e-225 719.0
MMD2_k127_395091_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 473.0
MMD2_k127_395091_10 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001647 261.0
MMD2_k127_395091_11 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000005093 229.0
MMD2_k127_395091_12 LysR substrate binding domain K05817 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000003251 203.0
MMD2_k127_395091_13 - - - - 0.000000000000000000000000000000000000000000000000002674 194.0
MMD2_k127_395091_15 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000004594 184.0
MMD2_k127_395091_16 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000407 175.0
MMD2_k127_395091_17 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000000000000000000000000000006182 162.0
MMD2_k127_395091_18 peptidase - - - 0.0000000000000000000000000000000000000000008021 164.0
MMD2_k127_395091_19 - - - - 0.00000000000000000000000000000000004219 147.0
MMD2_k127_395091_20 - - - - 0.0000000000000000000000000000001134 130.0
MMD2_k127_395091_21 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000006341 131.0
MMD2_k127_395091_22 SnoaL-like domain - - - 0.000000000000000000000000000005448 126.0
MMD2_k127_395091_24 - - - - 0.000000000000000000000003377 107.0
MMD2_k127_395091_25 AAA ATPase domain - - - 0.00000000000000000007587 105.0
MMD2_k127_395091_26 Major Facilitator Superfamily K13021 - - 0.0000000000001839 84.0
MMD2_k127_395091_27 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000147 76.0
MMD2_k127_395091_28 dienelactone hydrolase - - - 0.000000000001615 76.0
MMD2_k127_395091_29 - - - - 0.000000000002059 73.0
MMD2_k127_395091_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 385.0
MMD2_k127_395091_30 Helix-turn-helix domain - - - 0.000000000005268 69.0
MMD2_k127_395091_31 BlaR1 peptidase M56 - - - 0.00000000127 63.0
MMD2_k127_395091_32 - - - - 0.0000008934 60.0
MMD2_k127_395091_33 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000003397 60.0
MMD2_k127_395091_34 Antibiotic biosynthesis monooxygenase - - - 0.000006187 53.0
MMD2_k127_395091_4 2-methylcitrate dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 332.0
MMD2_k127_395091_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 329.0
MMD2_k127_395091_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002999 276.0
MMD2_k127_395091_7 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001066 286.0
MMD2_k127_395091_8 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006072 259.0
MMD2_k127_395091_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004501 260.0
MMD2_k127_4043454_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1041.0
MMD2_k127_4043454_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.749e-320 995.0
MMD2_k127_4043454_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 281.0
MMD2_k127_4043454_12 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003131 276.0
MMD2_k127_4043454_13 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000002294 233.0
MMD2_k127_4043454_14 ankyrin repeat K15503 - - 0.000000000000000000000000000000000000000000000000000000000000139 232.0
MMD2_k127_4043454_15 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000149 197.0
MMD2_k127_4043454_16 heme binding K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000001009 192.0
MMD2_k127_4043454_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000005624 193.0
MMD2_k127_4043454_18 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000001315 160.0
MMD2_k127_4043454_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.939e-291 917.0
MMD2_k127_4043454_20 Glycine zipper - - - 0.0000000000000000000000000000000000000003484 165.0
MMD2_k127_4043454_21 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000002582 158.0
MMD2_k127_4043454_22 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000003394 126.0
MMD2_k127_4043454_23 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000003329 128.0
MMD2_k127_4043454_24 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000006318 90.0
MMD2_k127_4043454_25 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.000000000001211 78.0
MMD2_k127_4043454_26 Putative zinc- or iron-chelating domain - - - 0.00000000009382 71.0
MMD2_k127_4043454_27 Regulatory protein, FmdB family - - - 0.000000001403 64.0
MMD2_k127_4043454_28 - - - - 0.000001013 59.0
MMD2_k127_4043454_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.14e-236 749.0
MMD2_k127_4043454_4 Participates in both transcription termination and antitermination K02600 - - 3.472e-221 695.0
MMD2_k127_4043454_5 DNA topological change K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 578.0
MMD2_k127_4043454_6 Major facilitator Superfamily K18926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 552.0
MMD2_k127_4043454_7 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 544.0
MMD2_k127_4043454_8 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 450.0
MMD2_k127_4043454_9 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 354.0
MMD2_k127_4047735_0 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 9.544e-310 968.0
MMD2_k127_4047735_1 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 354.0
MMD2_k127_4047735_2 Superoxide dismutase K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 308.0
MMD2_k127_4047735_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003342 266.0
MMD2_k127_4047735_4 COG3473, Maleate cis-trans isomerase K01799,K06033 - 4.1.1.76,5.2.1.1 0.00000000000000000000000000000000000000000000000000000002044 206.0
MMD2_k127_4047735_5 helix_turn_helix, mercury resistance K19591 - - 0.000000000000000000000000000000000000000000001158 169.0
MMD2_k127_4047735_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000004629 117.0
MMD2_k127_4049822_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1376.0
MMD2_k127_4049822_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1274.0
MMD2_k127_4049822_10 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 286.0
MMD2_k127_4049822_11 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002165 248.0
MMD2_k127_4049822_13 - - - - 0.00007033 54.0
MMD2_k127_4049822_2 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 8.402e-254 797.0
MMD2_k127_4049822_3 Polysaccharide biosynthesis protein K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 568.0
MMD2_k127_4049822_4 Asparagine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 456.0
MMD2_k127_4049822_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 438.0
MMD2_k127_4049822_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 384.0
MMD2_k127_4049822_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 356.0
MMD2_k127_4049822_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 320.0
MMD2_k127_4049822_9 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 294.0
MMD2_k127_4077641_0 Binding-protein-dependent transport systems inner membrane component K02050 - - 1.584e-232 732.0
MMD2_k127_4077641_1 ABC transporter K02049 - - 1.724e-194 616.0
MMD2_k127_4077641_10 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000003199 189.0
MMD2_k127_4077641_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000003457 181.0
MMD2_k127_4077641_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000003076 177.0
MMD2_k127_4077641_13 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000005969 166.0
MMD2_k127_4077641_14 Phage shock protein A K03615,K03969,K09749,K21471 - - 0.0000000000000000000000000000001822 132.0
MMD2_k127_4077641_15 - - - - 0.0000000000000000000000003436 118.0
MMD2_k127_4077641_16 - - - - 0.00000000000000000000131 105.0
MMD2_k127_4077641_17 - - - - 0.00000000008634 68.0
MMD2_k127_4077641_18 - - - - 0.00000000307 69.0
MMD2_k127_4077641_19 - - - - 0.000000008659 66.0
MMD2_k127_4077641_2 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 567.0
MMD2_k127_4077641_20 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000008795 59.0
MMD2_k127_4077641_21 - - - - 0.000005287 59.0
MMD2_k127_4077641_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 554.0
MMD2_k127_4077641_4 von Willebrand factor, type A K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 445.0
MMD2_k127_4077641_5 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 327.0
MMD2_k127_4077641_6 response regulator K07776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 308.0
MMD2_k127_4077641_7 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002467 279.0
MMD2_k127_4077641_8 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000143 248.0
MMD2_k127_4077641_9 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000001227 245.0
MMD2_k127_4078572_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00480 - 1.14.13.1 1.267e-239 752.0
MMD2_k127_4078572_1 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 612.0
MMD2_k127_4078572_10 Helix-turn-helix domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 362.0
MMD2_k127_4078572_11 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 345.0
MMD2_k127_4078572_12 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 334.0
MMD2_k127_4078572_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 291.0
MMD2_k127_4078572_14 thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 289.0
MMD2_k127_4078572_15 PFAM GPR1 FUN34 yaaH family protein K07034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004478 280.0
MMD2_k127_4078572_16 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000344 259.0
MMD2_k127_4078572_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001016 269.0
MMD2_k127_4078572_18 protein-(glutamine-N5) methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 261.0
MMD2_k127_4078572_19 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000001268 254.0
MMD2_k127_4078572_2 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 480.0
MMD2_k127_4078572_20 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.000000000000000000000000000000000000000000000000000000001587 204.0
MMD2_k127_4078572_21 - - - - 0.0000000000000000000000000000000000000000000000001636 190.0
MMD2_k127_4078572_22 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000122 183.0
MMD2_k127_4078572_23 - - - - 0.0000000000000000000000000000000000008842 143.0
MMD2_k127_4078572_24 E COG0620 Methionine synthase II (cobalamin-independent) - - - 0.000000000000000000000001458 104.0
MMD2_k127_4078572_25 - - - - 0.00000000000000000000246 99.0
MMD2_k127_4078572_26 Cupin domain - - - 0.0000000000004626 77.0
MMD2_k127_4078572_27 Lipocalin-like domain - - - 0.000000000002298 78.0
MMD2_k127_4078572_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 461.0
MMD2_k127_4078572_4 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 470.0
MMD2_k127_4078572_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 415.0
MMD2_k127_4078572_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 408.0
MMD2_k127_4078572_7 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 387.0
MMD2_k127_4078572_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 374.0
MMD2_k127_4078572_9 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 363.0
MMD2_k127_4118765_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 2.294e-241 756.0
MMD2_k127_4118765_1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.695e-214 674.0
MMD2_k127_4118765_10 Aminomethyltransferase folate-binding domain - - - 0.0001366 53.0
MMD2_k127_4118765_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 604.0
MMD2_k127_4118765_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 465.0
MMD2_k127_4118765_4 PFAM pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 465.0
MMD2_k127_4118765_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 452.0
MMD2_k127_4118765_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 338.0
MMD2_k127_4118765_7 Cytochrome C' - - - 0.0000000000000000000000000000000000000001667 157.0
MMD2_k127_4118765_8 PFAM extracellular solute-binding protein family 1 K02020,K22003 - 5.3.3.7 0.000000000000000000000000000000000001091 160.0
MMD2_k127_4118765_9 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000007025 129.0
MMD2_k127_4206544_0 MacB-like periplasmic core domain - - - 2.452e-251 801.0
MMD2_k127_4206544_1 MacB-like periplasmic core domain - - - 1.256e-244 781.0
MMD2_k127_4206544_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003727 265.0
MMD2_k127_4206544_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000001394 239.0
MMD2_k127_4206544_12 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003465 235.0
MMD2_k127_4206544_13 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000537 227.0
MMD2_k127_4206544_14 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000000000000000001104 201.0
MMD2_k127_4206544_15 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000672 204.0
MMD2_k127_4206544_16 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000003046 184.0
MMD2_k127_4206544_17 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000003309 173.0
MMD2_k127_4206544_18 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000003397 169.0
MMD2_k127_4206544_19 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000001417 172.0
MMD2_k127_4206544_2 COG4993 Glucose dehydrogenase - - - 3.264e-211 673.0
MMD2_k127_4206544_20 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000004611 130.0
MMD2_k127_4206544_21 sister chromatid segregation - - - 0.00000000000000000000000008507 117.0
MMD2_k127_4206544_22 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 0.00000000000000000000000797 102.0
MMD2_k127_4206544_3 MacB-like periplasmic core domain - - - 7.105e-204 662.0
MMD2_k127_4206544_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 550.0
MMD2_k127_4206544_5 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 383.0
MMD2_k127_4206544_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 372.0
MMD2_k127_4206544_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 338.0
MMD2_k127_4206544_8 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 302.0
MMD2_k127_4206544_9 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
MMD2_k127_4235346_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.461e-302 943.0
MMD2_k127_4235346_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 3.193e-282 893.0
MMD2_k127_4235346_10 Glutamate-cysteine ligase family 2(GCS2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 419.0
MMD2_k127_4235346_11 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 439.0
MMD2_k127_4235346_12 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 421.0
MMD2_k127_4235346_13 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 374.0
MMD2_k127_4235346_14 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 333.0
MMD2_k127_4235346_15 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 329.0
MMD2_k127_4235346_16 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000194 293.0
MMD2_k127_4235346_17 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001019 272.0
MMD2_k127_4235346_18 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000002297 284.0
MMD2_k127_4235346_19 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000008332 231.0
MMD2_k127_4235346_2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01200,K01214 - 3.2.1.41,3.2.1.68 3.091e-226 751.0
MMD2_k127_4235346_20 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000001811 226.0
MMD2_k127_4235346_21 Protein of unknown function (DUF1097) - - - 0.000000000000000000000000000000000000000000000000006016 186.0
MMD2_k127_4235346_22 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000002738 150.0
MMD2_k127_4235346_23 Uncharacterized ACR, COG1678 K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000004941 125.0
MMD2_k127_4235346_24 - - - - 0.0000000000000000000000005508 115.0
MMD2_k127_4235346_25 - - - - 0.00000000000000000000000142 113.0
MMD2_k127_4235346_3 PFAM Orn DAP Arg decarboxylase 2 K01585 - 4.1.1.19 3.583e-212 677.0
MMD2_k127_4235346_4 Radical SAM superfamily K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 575.0
MMD2_k127_4235346_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 548.0
MMD2_k127_4235346_6 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 537.0
MMD2_k127_4235346_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 537.0
MMD2_k127_4235346_8 RimK-like ATPgrasp N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 514.0
MMD2_k127_4235346_9 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 481.0
MMD2_k127_42392_1 Flavin containing amine oxidoreductase - - - 2.673e-207 664.0
MMD2_k127_42392_10 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000167 187.0
MMD2_k127_42392_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001449 156.0
MMD2_k127_42392_12 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000004236 156.0
MMD2_k127_42392_13 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000003292 159.0
MMD2_k127_42392_14 PFAM Membrane protein of K08972 - - 0.0000000000000000000000000001012 119.0
MMD2_k127_42392_15 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000004071 120.0
MMD2_k127_42392_16 - - - - 0.00000000000000001109 86.0
MMD2_k127_42392_17 - - - - 0.0003912 43.0
MMD2_k127_42392_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 612.0
MMD2_k127_42392_3 Protein of unknown function (DUF1587) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 604.0
MMD2_k127_42392_4 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 478.0
MMD2_k127_42392_5 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 396.0
MMD2_k127_42392_6 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 363.0
MMD2_k127_42392_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 348.0
MMD2_k127_42392_8 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004162 281.0
MMD2_k127_42392_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002864 259.0
MMD2_k127_4283430_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 580.0
MMD2_k127_4283430_1 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 518.0
MMD2_k127_4283430_10 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000002178 157.0
MMD2_k127_4283430_12 - - - - 0.000000000000000000000008057 103.0
MMD2_k127_4283430_13 membrane - - - 0.000000000000001572 85.0
MMD2_k127_4283430_14 Dehydrogenase K17760 - 1.1.9.1 0.000000000000782 74.0
MMD2_k127_4283430_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 512.0
MMD2_k127_4283430_3 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 407.0
MMD2_k127_4283430_4 PFAM Major facilitator superfamily MFS-1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 321.0
MMD2_k127_4283430_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003906 282.0
MMD2_k127_4283430_6 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007932 258.0
MMD2_k127_4283430_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002114 237.0
MMD2_k127_4283430_8 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000007861 233.0
MMD2_k127_4283430_9 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000002898 235.0
MMD2_k127_4381638_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 432.0
MMD2_k127_4381638_1 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 322.0
MMD2_k127_4381638_2 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 297.0
MMD2_k127_4381638_3 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
MMD2_k127_4381638_4 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001911 266.0
MMD2_k127_4381638_5 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000415 246.0
MMD2_k127_4381638_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000001257 163.0
MMD2_k127_4381638_7 Acetyltransferase, gnat family - - - 0.00000000000000000000000000000002894 130.0
MMD2_k127_4381638_8 - - - - 0.000000000000000000001998 104.0
MMD2_k127_4386765_0 UPF0313 protein - - - 0.0 1051.0
MMD2_k127_4386765_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1025.0
MMD2_k127_4386765_10 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 417.0
MMD2_k127_4386765_11 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 416.0
MMD2_k127_4386765_12 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 411.0
MMD2_k127_4386765_13 Major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 386.0
MMD2_k127_4386765_14 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 354.0
MMD2_k127_4386765_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 342.0
MMD2_k127_4386765_16 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 340.0
MMD2_k127_4386765_17 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 301.0
MMD2_k127_4386765_18 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 309.0
MMD2_k127_4386765_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
MMD2_k127_4386765_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.612e-288 899.0
MMD2_k127_4386765_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002098 270.0
MMD2_k127_4386765_21 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000412 257.0
MMD2_k127_4386765_22 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001532 251.0
MMD2_k127_4386765_23 belongs to the bacterial solute-binding protein 3 family K02030,K02424,K10036 - - 0.000000000000000000000000000000000000000000000000000000000000000000002552 244.0
MMD2_k127_4386765_24 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000004182 222.0
MMD2_k127_4386765_25 Transcriptional K03719 - - 0.0000000000000000000000000000000000000000000000000000000000001435 219.0
MMD2_k127_4386765_26 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000001817 198.0
MMD2_k127_4386765_27 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000001879 193.0
MMD2_k127_4386765_28 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000003373 170.0
MMD2_k127_4386765_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000004393 178.0
MMD2_k127_4386765_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.405e-230 726.0
MMD2_k127_4386765_30 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000008296 146.0
MMD2_k127_4386765_31 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000000000000000000006855 123.0
MMD2_k127_4386765_32 Protein conserved in bacteria - - - 0.000000000000000000000000002957 117.0
MMD2_k127_4386765_33 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000000007279 106.0
MMD2_k127_4386765_34 Domain of unknown function (DUF4389) - - - 0.0000000000000000005572 90.0
MMD2_k127_4386765_35 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000008652 85.0
MMD2_k127_4386765_36 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000008367 82.0
MMD2_k127_4386765_37 PilZ domain - - - 0.00000000000001733 76.0
MMD2_k127_4386765_38 - - - - 0.0000000000002398 76.0
MMD2_k127_4386765_39 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000008743 77.0
MMD2_k127_4386765_4 Aminotransferase class I and II K00812 - 2.6.1.1 8.4e-216 677.0
MMD2_k127_4386765_40 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000622 63.0
MMD2_k127_4386765_41 NfeD-like C-terminal, partner-binding - - - 0.00000001135 62.0
MMD2_k127_4386765_42 Putative zinc-finger - - - 0.00000001594 62.0
MMD2_k127_4386765_43 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001874 63.0
MMD2_k127_4386765_44 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0003851 45.0
MMD2_k127_4386765_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 583.0
MMD2_k127_4386765_6 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 546.0
MMD2_k127_4386765_7 Multicopper oxidase K04753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 518.0
MMD2_k127_4386765_8 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 507.0
MMD2_k127_4386765_9 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 489.0
MMD2_k127_441849_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 2.433e-229 719.0
MMD2_k127_441849_1 Dehydrogenase K00114 - 1.1.2.8 3.265e-202 645.0
MMD2_k127_441849_10 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 387.0
MMD2_k127_441849_11 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 385.0
MMD2_k127_441849_12 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 379.0
MMD2_k127_441849_13 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005356 274.0
MMD2_k127_441849_14 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003216 263.0
MMD2_k127_441849_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000005812 243.0
MMD2_k127_441849_16 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001738 250.0
MMD2_k127_441849_17 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007183 237.0
MMD2_k127_441849_18 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001194 241.0
MMD2_k127_441849_19 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000003259 208.0
MMD2_k127_441849_2 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 609.0
MMD2_k127_441849_20 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000000000000000005316 193.0
MMD2_k127_441849_21 - - - - 0.00000000000000000000000000000000003274 139.0
MMD2_k127_441849_22 PFAM MAPEG family K00799 GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0042221,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.5.1.18 0.0000000000000000000000000000001301 127.0
MMD2_k127_441849_23 - - - - 0.00000000000000000000000003145 117.0
MMD2_k127_441849_24 - - - - 0.000000000000000000000000289 117.0
MMD2_k127_441849_25 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000001081 108.0
MMD2_k127_441849_26 - - - - 0.000000000000000000000002421 113.0
MMD2_k127_441849_27 - - - - 0.00000000000000000000007492 114.0
MMD2_k127_441849_28 - - - - 0.00000000000000000000447 97.0
MMD2_k127_441849_29 - - - - 0.00000000000000000006669 98.0
MMD2_k127_441849_3 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 613.0
MMD2_k127_441849_30 - - - - 0.0000000000000000002549 94.0
MMD2_k127_441849_31 AAA domain - - - 0.000000000000000001875 100.0
MMD2_k127_441849_32 - - - - 0.00000000000000008015 85.0
MMD2_k127_441849_33 - - - - 0.0000000000000002753 90.0
MMD2_k127_441849_34 - - - - 0.0000000000000004014 85.0
MMD2_k127_441849_35 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000001498 84.0
MMD2_k127_441849_36 - - - - 0.0000000000000308 79.0
MMD2_k127_441849_37 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000008926 85.0
MMD2_k127_441849_38 - - - - 0.000000000003133 74.0
MMD2_k127_441849_39 Cytochrome c K17760 - 1.1.9.1 0.00000000002054 70.0
MMD2_k127_441849_4 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 576.0
MMD2_k127_441849_40 - - - - 0.00001865 53.0
MMD2_k127_441849_5 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 565.0
MMD2_k127_441849_6 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 536.0
MMD2_k127_441849_7 Short chain fatty acid transporter K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 509.0
MMD2_k127_441849_8 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 495.0
MMD2_k127_441849_9 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 406.0
MMD2_k127_4481157_0 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 626.0
MMD2_k127_4481157_1 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 527.0
MMD2_k127_4481157_10 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000012 270.0
MMD2_k127_4481157_11 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000001958 192.0
MMD2_k127_4481157_12 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000222 189.0
MMD2_k127_4481157_14 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.00000000000000000000000000000000000000000000003704 176.0
MMD2_k127_4481157_17 heat shock protein DnaJ K05516 - - 0.000000000000000000000000000000000000000001325 159.0
MMD2_k127_4481157_18 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000447 157.0
MMD2_k127_4481157_19 - - - - 0.00000000000000000000000000000000000002249 153.0
MMD2_k127_4481157_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 503.0
MMD2_k127_4481157_20 MerR HTH family regulatory protein K18997 - - 0.0000000000000000000004032 104.0
MMD2_k127_4481157_21 - - - - 0.000000000000000002893 96.0
MMD2_k127_4481157_3 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 477.0
MMD2_k127_4481157_4 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 506.0
MMD2_k127_4481157_5 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 415.0
MMD2_k127_4481157_6 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 415.0
MMD2_k127_4481157_7 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 391.0
MMD2_k127_4481157_8 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 380.0
MMD2_k127_4481157_9 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 361.0
MMD2_k127_4484682_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1056.0
MMD2_k127_4484682_1 glucan 1,4-alpha-glucosidase K01178 - 3.2.1.3 7.481e-295 925.0
MMD2_k127_4484682_10 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 370.0
MMD2_k127_4484682_11 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 370.0
MMD2_k127_4484682_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 344.0
MMD2_k127_4484682_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 331.0
MMD2_k127_4484682_14 Tannase and feruloyl esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 303.0
MMD2_k127_4484682_15 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001004 276.0
MMD2_k127_4484682_16 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001302 275.0
MMD2_k127_4484682_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005126 261.0
MMD2_k127_4484682_18 2Fe-2S -binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
MMD2_k127_4484682_19 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003593 235.0
MMD2_k127_4484682_2 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 561.0
MMD2_k127_4484682_20 - - - - 0.000000000000000000000000000000000000000000000000000000000004131 212.0
MMD2_k127_4484682_21 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000004605 198.0
MMD2_k127_4484682_22 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000001585 199.0
MMD2_k127_4484682_23 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000005233 185.0
MMD2_k127_4484682_24 Cytochrome b - - - 0.0000000000000000000000000000000000000000000000000685 186.0
MMD2_k127_4484682_25 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000962 183.0
MMD2_k127_4484682_26 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000006889 180.0
MMD2_k127_4484682_27 Copper resistance protein D K07245,K14166 - - 0.0000000000000000000000000000000000000000000001906 186.0
MMD2_k127_4484682_28 LexA-binding, inner membrane-associated putative hydrolase - - - 0.00000000000000000000000000000000000000000005326 174.0
MMD2_k127_4484682_29 Short C-terminal domain K08982 - - 0.00000000000000000000000000000000000000002605 155.0
MMD2_k127_4484682_3 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 506.0
MMD2_k127_4484682_30 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000007189 156.0
MMD2_k127_4484682_31 NmrA-like family - - - 0.00000000000000000000000000000000000004069 154.0
MMD2_k127_4484682_32 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000001117 159.0
MMD2_k127_4484682_33 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000000000000000000000000001706 143.0
MMD2_k127_4484682_34 - - - - 0.0000000000000000000000000000000002959 150.0
MMD2_k127_4484682_35 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000001601 141.0
MMD2_k127_4484682_36 - - - - 0.000000000000000000000000000000001884 132.0
MMD2_k127_4484682_37 Saccharopine dehydrogenase - - - 0.00000000000000000000000000001322 131.0
MMD2_k127_4484682_38 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000006184 119.0
MMD2_k127_4484682_39 RDD family - - - 0.00000000000000000000000003527 119.0
MMD2_k127_4484682_4 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 489.0
MMD2_k127_4484682_40 sequence-specific DNA binding - - - 0.00000000000000000000001036 111.0
MMD2_k127_4484682_41 - - - - 0.00000000000000000000008933 110.0
MMD2_k127_4484682_42 Domain of unknown function (DUF4440) - - - 0.0000000000000000000001247 102.0
MMD2_k127_4484682_43 response regulator - - - 0.000000000000000000002339 105.0
MMD2_k127_4484682_44 - - - - 0.000000000000000000459 95.0
MMD2_k127_4484682_45 Protein of unknown function (DUF1109) - - - 0.0000000000000000008273 94.0
MMD2_k127_4484682_46 cytochrome - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000006006 89.0
MMD2_k127_4484682_47 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000002181 77.0
MMD2_k127_4484682_49 CopC domain K07156 - - 0.0000000000005358 75.0
MMD2_k127_4484682_5 Multi-copper K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 461.0
MMD2_k127_4484682_51 - - - - 0.0000002006 64.0
MMD2_k127_4484682_52 Protein of unknown function (DUF1090) - - - 0.0005026 49.0
MMD2_k127_4484682_6 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 467.0
MMD2_k127_4484682_7 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 460.0
MMD2_k127_4484682_8 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 424.0
MMD2_k127_4484682_9 PFAM Molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 418.0
MMD2_k127_45456_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1124.0
MMD2_k127_45456_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 3.495e-307 960.0
MMD2_k127_45456_10 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 333.0
MMD2_k127_45456_11 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 326.0
MMD2_k127_45456_12 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 313.0
MMD2_k127_45456_13 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 300.0
MMD2_k127_45456_14 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 295.0
MMD2_k127_45456_15 cyclic-guanylate-specific phosphodiesterase activity K21025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 309.0
MMD2_k127_45456_16 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000002088 276.0
MMD2_k127_45456_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001906 262.0
MMD2_k127_45456_18 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
MMD2_k127_45456_19 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000003671 244.0
MMD2_k127_45456_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.335e-216 682.0
MMD2_k127_45456_20 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000009659 240.0
MMD2_k127_45456_21 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000208 185.0
MMD2_k127_45456_22 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000002459 164.0
MMD2_k127_45456_23 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000179 142.0
MMD2_k127_45456_24 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000004709 142.0
MMD2_k127_45456_25 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0000000000000000000000000001125 115.0
MMD2_k127_45456_26 membrane protein, required for colicin V production K03558 - - 0.0000000000000000000000002992 113.0
MMD2_k127_45456_27 Catalyzes the addition of the first glucose residue to the LPS core K02844 - - 0.0000000000000000000000003303 118.0
MMD2_k127_45456_28 - - - - 0.000000000000000000008461 99.0
MMD2_k127_45456_29 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000004985 94.0
MMD2_k127_45456_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.212e-212 666.0
MMD2_k127_45456_30 - - - - 0.0000000000001722 70.0
MMD2_k127_45456_31 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000005623 77.0
MMD2_k127_45456_32 Sporulation related domain K03749 - - 0.000000000003187 75.0
MMD2_k127_45456_34 translation initiation factor activity K08086 - - 0.0000006768 63.0
MMD2_k127_45456_35 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000006165 53.0
MMD2_k127_45456_36 DNA integration - - - 0.0003166 44.0
MMD2_k127_45456_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 545.0
MMD2_k127_45456_5 Capsule assembly protein Wzi - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 413.0
MMD2_k127_45456_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 388.0
MMD2_k127_45456_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 360.0
MMD2_k127_45456_8 lysine 2,3-aminomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 344.0
MMD2_k127_45456_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 329.0
MMD2_k127_4559472_0 TonB dependent receptor - - - 2.582e-222 710.0
MMD2_k127_4559472_1 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 2.755e-202 639.0
MMD2_k127_4559472_10 transport, permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 402.0
MMD2_k127_4559472_11 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 392.0
MMD2_k127_4559472_12 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 382.0
MMD2_k127_4559472_13 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 383.0
MMD2_k127_4559472_14 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 351.0
MMD2_k127_4559472_15 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 350.0
MMD2_k127_4559472_16 Methionine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 341.0
MMD2_k127_4559472_17 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 333.0
MMD2_k127_4559472_18 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 330.0
MMD2_k127_4559472_19 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 323.0
MMD2_k127_4559472_2 DNA topological change K03168 - 5.99.1.2 5.251e-201 653.0
MMD2_k127_4559472_20 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
MMD2_k127_4559472_21 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004412 282.0
MMD2_k127_4559472_22 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001251 269.0
MMD2_k127_4559472_23 dehydratase K18290 - 4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000005359 255.0
MMD2_k127_4559472_24 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000003471 216.0
MMD2_k127_4559472_25 - - - - 0.00000000000000000000000000000000000000000000000000000000002934 222.0
MMD2_k127_4559472_26 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001559 205.0
MMD2_k127_4559472_27 - - - - 0.0000000000000000000000000000000000000000000000001652 191.0
MMD2_k127_4559472_28 ankyrin repeat K15503 - - 0.00000000000000000000000000000000000000000001198 183.0
MMD2_k127_4559472_29 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000001861 169.0
MMD2_k127_4559472_3 Major Facilitator Superfamily - - - 2.198e-197 628.0
MMD2_k127_4559472_30 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000004511 152.0
MMD2_k127_4559472_31 Protein chain release factor B K15034 - - 0.000000000000000000000000000000000000166 147.0
MMD2_k127_4559472_32 - - - - 0.000000000000000000000000000000005303 134.0
MMD2_k127_4559472_33 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000003157 130.0
MMD2_k127_4559472_34 glucose sorbosone - - - 0.00000000000000000000000000000005551 128.0
MMD2_k127_4559472_35 - - - - 0.0000000000000000000000000004498 122.0
MMD2_k127_4559472_36 - - - - 0.00000000000000000000000003684 113.0
MMD2_k127_4559472_37 response to abiotic stimulus K06867 - - 0.000000000000000000000001055 113.0
MMD2_k127_4559472_38 Sulfotransferase family - - - 0.00000000000000000000001121 111.0
MMD2_k127_4559472_39 - - - - 0.00000000000000000000007884 110.0
MMD2_k127_4559472_4 Dehydrogenase K00114 - 1.1.2.8 4.796e-195 627.0
MMD2_k127_4559472_40 - - - - 0.0000000000000000000001308 109.0
MMD2_k127_4559472_41 - - - - 0.0000000000000000000006472 107.0
MMD2_k127_4559472_42 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000000000003768 97.0
MMD2_k127_4559472_43 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000005243 94.0
MMD2_k127_4559472_44 - - - - 0.0000000000000000005889 96.0
MMD2_k127_4559472_45 PFAM FAD linked oxidase domain protein K05797 - 1.17.99.1 0.000000000000000003439 84.0
MMD2_k127_4559472_46 - - - - 0.000000000000000003969 90.0
MMD2_k127_4559472_48 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000005384 86.0
MMD2_k127_4559472_49 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000001738 78.0
MMD2_k127_4559472_5 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 501.0
MMD2_k127_4559472_50 - - - - 0.0000000000004182 77.0
MMD2_k127_4559472_51 - - - - 0.00000006541 59.0
MMD2_k127_4559472_52 - - - - 0.0000004293 59.0
MMD2_k127_4559472_6 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 502.0
MMD2_k127_4559472_7 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 475.0
MMD2_k127_4559472_8 Uncharacterised MFS-type transporter YbfB K05548,K05819,K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 456.0
MMD2_k127_4559472_9 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 458.0
MMD2_k127_4561413_0 AcrB/AcrD/AcrF family - - - 0.0 1287.0
MMD2_k127_4561413_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1201.0
MMD2_k127_4561413_10 FAD linked oxidase domain protein K05797 - 1.17.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 554.0
MMD2_k127_4561413_11 Dehydrogenase K00114,K17760,K20936,K21676,K22473 - 1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 508.0
MMD2_k127_4561413_12 SMART transcription factor jumonji jmjC K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 485.0
MMD2_k127_4561413_13 Cys/Met metabolism PLP-dependent enzyme K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 470.0
MMD2_k127_4561413_14 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 464.0
MMD2_k127_4561413_15 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 459.0
MMD2_k127_4561413_16 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 460.0
MMD2_k127_4561413_17 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 425.0
MMD2_k127_4561413_18 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 414.0
MMD2_k127_4561413_19 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 417.0
MMD2_k127_4561413_2 GTP-binding protein TypA K06207 - - 1.476e-282 879.0
MMD2_k127_4561413_20 Major facilitator Superfamily K03762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 406.0
MMD2_k127_4561413_21 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 378.0
MMD2_k127_4561413_22 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 390.0
MMD2_k127_4561413_23 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 344.0
MMD2_k127_4561413_24 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 349.0
MMD2_k127_4561413_25 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 344.0
MMD2_k127_4561413_26 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 336.0
MMD2_k127_4561413_27 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 332.0
MMD2_k127_4561413_28 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 348.0
MMD2_k127_4561413_29 COG0421 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 325.0
MMD2_k127_4561413_3 TonB dependent receptor K02014 - - 8.023e-276 869.0
MMD2_k127_4561413_30 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 329.0
MMD2_k127_4561413_31 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 324.0
MMD2_k127_4561413_32 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 311.0
MMD2_k127_4561413_33 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 302.0
MMD2_k127_4561413_34 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 314.0
MMD2_k127_4561413_35 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 306.0
MMD2_k127_4561413_36 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 295.0
MMD2_k127_4561413_37 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 293.0
MMD2_k127_4561413_38 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000315 263.0
MMD2_k127_4561413_39 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002511 269.0
MMD2_k127_4561413_4 PQQ enzyme repeat K00114 - 1.1.2.8 4.197e-235 744.0
MMD2_k127_4561413_40 Transcriptional regulatory protein, C terminal K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000006076 238.0
MMD2_k127_4561413_41 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000003525 220.0
MMD2_k127_4561413_42 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000001975 225.0
MMD2_k127_4561413_43 - - - - 0.000000000000000000000000000000000000000000000000000000000003862 215.0
MMD2_k127_4561413_44 HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000006767 214.0
MMD2_k127_4561413_45 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000005255 213.0
MMD2_k127_4561413_46 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.00000000000000000000000000000000000000000000000000000001737 211.0
MMD2_k127_4561413_47 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000005006 196.0
MMD2_k127_4561413_48 Predicted integral membrane protein (DUF2269) - - - 0.0000000000000000000000000000000000000000000000000003402 203.0
MMD2_k127_4561413_49 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000009589 201.0
MMD2_k127_4561413_5 DNA topological change K03168 - 5.99.1.2 7.394e-232 743.0
MMD2_k127_4561413_50 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000003601 194.0
MMD2_k127_4561413_51 glyoxalase III activity K02005 - - 0.0000000000000000000000000000000000000000000000001022 183.0
MMD2_k127_4561413_52 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000004425 180.0
MMD2_k127_4561413_53 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000002995 173.0
MMD2_k127_4561413_54 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000004233 175.0
MMD2_k127_4561413_55 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000001307 167.0
MMD2_k127_4561413_56 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000002903 175.0
MMD2_k127_4561413_57 Redoxin - - - 0.0000000000000000000000000000000000000002246 155.0
MMD2_k127_4561413_58 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000000000000000000000000000000000005935 152.0
MMD2_k127_4561413_59 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000323 164.0
MMD2_k127_4561413_6 PQQ-like domain K00117 - 1.1.5.2 1.133e-218 701.0
MMD2_k127_4561413_60 - - - - 0.0000000000000000000000000000000000006733 160.0
MMD2_k127_4561413_61 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000002241 141.0
MMD2_k127_4561413_62 PFAM branched-chain amino acid transport - - - 0.000000000000000000000000000000001164 150.0
MMD2_k127_4561413_63 - - - - 0.0000000000000000000000000000004819 130.0
MMD2_k127_4561413_64 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000005289 130.0
MMD2_k127_4561413_65 ECF sigma factor K03088 - - 0.0000000000000000000000000004679 123.0
MMD2_k127_4561413_66 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000001714 129.0
MMD2_k127_4561413_67 Lysyl oxidase - - - 0.0000000000000000000000002534 121.0
MMD2_k127_4561413_68 PAP2 superfamily - - - 0.000000000000000000000001733 116.0
MMD2_k127_4561413_69 - - - - 0.000000000000000000000009045 106.0
MMD2_k127_4561413_7 TonB dependent receptor - - - 2.671e-211 694.0
MMD2_k127_4561413_70 - - - - 0.00000000000000000000001336 109.0
MMD2_k127_4561413_71 Domain of unknown function (DUF4266) - - - 0.00000000000000000000004012 100.0
MMD2_k127_4561413_72 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000008155 108.0
MMD2_k127_4561413_73 COG0457 FOG TPR repeat - - - 0.00000000000000000002254 104.0
MMD2_k127_4561413_74 - - - - 0.00000000000000000007297 102.0
MMD2_k127_4561413_76 - - - - 0.0000000000000001087 89.0
MMD2_k127_4561413_78 - - - - 0.0000000000000007549 88.0
MMD2_k127_4561413_8 - - - - 9.103e-208 669.0
MMD2_k127_4561413_80 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000001901 76.0
MMD2_k127_4561413_81 AntiSigma factor - - - 0.000000000002862 76.0
MMD2_k127_4561413_82 - - - - 0.00000000002227 70.0
MMD2_k127_4561413_83 - - - - 0.000000001446 71.0
MMD2_k127_4561413_85 - - - - 0.0000009386 59.0
MMD2_k127_4561413_86 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000006916 54.0
MMD2_k127_4561413_87 - - - - 0.0008015 48.0
MMD2_k127_4561413_9 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 609.0
MMD2_k127_4594674_0 - - - - 4.506e-298 932.0
MMD2_k127_4594674_1 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K10011 - 1.1.1.305,2.1.2.13 4.355e-295 919.0
MMD2_k127_4594674_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 331.0
MMD2_k127_4594674_11 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K13014 GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 332.0
MMD2_k127_4594674_12 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 307.0
MMD2_k127_4594674_13 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 296.0
MMD2_k127_4594674_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001138 253.0
MMD2_k127_4594674_15 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009558 248.0
MMD2_k127_4594674_16 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000007195 228.0
MMD2_k127_4594674_17 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000001633 199.0
MMD2_k127_4594674_18 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000005495 177.0
MMD2_k127_4594674_19 NUDIX domain - - - 0.0000000000000000000000000000000000000000000103 186.0
MMD2_k127_4594674_2 PQQ enzyme repeat - - - 1.097e-217 698.0
MMD2_k127_4594674_20 glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000001679 160.0
MMD2_k127_4594674_21 SnoaL-like domain - - - 0.0000000000000000000000000000000008649 138.0
MMD2_k127_4594674_22 - - - - 0.00000000000000000000000049 119.0
MMD2_k127_4594674_23 - - - - 0.0000000000000000000000112 108.0
MMD2_k127_4594674_24 - - - - 0.000000000000000000000268 108.0
MMD2_k127_4594674_25 GtrA-like protein - - - 0.000000000000000000004706 105.0
MMD2_k127_4594674_26 - - - - 0.0000000000000005618 82.0
MMD2_k127_4594674_27 - - - - 0.000000000000001222 90.0
MMD2_k127_4594674_28 Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane K12963 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000384 72.0
MMD2_k127_4594674_29 EamA-like transporter family - - - 0.000004384 53.0
MMD2_k127_4594674_3 metal-dependent hydrolase of the TIM-barrel fold K03392,K10220 - 4.1.1.45,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 540.0
MMD2_k127_4594674_4 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 542.0
MMD2_k127_4594674_5 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07806 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 483.0
MMD2_k127_4594674_6 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 494.0
MMD2_k127_4594674_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 369.0
MMD2_k127_4594674_8 Glycosyltransferase like family 2 K10012,K20534 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 369.0
MMD2_k127_4594674_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 330.0
MMD2_k127_4626016_0 Aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 3.872e-233 731.0
MMD2_k127_4626016_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.884e-222 706.0
MMD2_k127_4626016_10 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 392.0
MMD2_k127_4626016_11 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 372.0
MMD2_k127_4626016_12 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 357.0
MMD2_k127_4626016_13 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 379.0
MMD2_k127_4626016_14 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 340.0
MMD2_k127_4626016_15 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 334.0
MMD2_k127_4626016_16 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 306.0
MMD2_k127_4626016_17 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001515 295.0
MMD2_k127_4626016_18 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005351 257.0
MMD2_k127_4626016_19 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000005126 203.0
MMD2_k127_4626016_2 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 3.503e-204 642.0
MMD2_k127_4626016_20 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000002113 203.0
MMD2_k127_4626016_21 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000001185 194.0
MMD2_k127_4626016_22 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000006389 186.0
MMD2_k127_4626016_23 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000001079 179.0
MMD2_k127_4626016_24 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000002634 162.0
MMD2_k127_4626016_25 SnoaL-like domain - - - 0.000000000000000000000000000000000000003845 152.0
MMD2_k127_4626016_26 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000001224 146.0
MMD2_k127_4626016_27 Putative esterase K07017 - - 0.0000000000000000000000000000000001144 144.0
MMD2_k127_4626016_28 Protein of unknown function (DUF2799) - - - 0.0000000000000000000000000000006851 141.0
MMD2_k127_4626016_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000004501 117.0
MMD2_k127_4626016_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 545.0
MMD2_k127_4626016_30 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000003651 117.0
MMD2_k127_4626016_31 general secretion pathway protein D K02453 - - 0.000000000000000000001357 102.0
MMD2_k127_4626016_32 Predicted membrane protein (DUF2306) - - - 0.000000000000000000644 94.0
MMD2_k127_4626016_33 - - - - 0.00000000118 69.0
MMD2_k127_4626016_34 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000002038 65.0
MMD2_k127_4626016_35 cytochrome - - - 0.0000003481 59.0
MMD2_k127_4626016_36 - - - - 0.00002238 55.0
MMD2_k127_4626016_37 Gram-negative bacterial TonB protein C-terminal - - - 0.0001053 53.0
MMD2_k127_4626016_38 subunit of a heme lyase K02200 - - 0.0002157 50.0
MMD2_k127_4626016_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 519.0
MMD2_k127_4626016_5 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 477.0
MMD2_k127_4626016_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 459.0
MMD2_k127_4626016_8 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 409.0
MMD2_k127_4626016_9 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 400.0
MMD2_k127_4646457_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 393.0
MMD2_k127_4646457_1 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 293.0
MMD2_k127_4646457_2 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000001032 220.0
MMD2_k127_4646457_3 PepSY-associated TM region - - - 0.0000000000000000000000000003774 130.0
MMD2_k127_4670258_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - 5.446e-245 786.0
MMD2_k127_4670258_1 Lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 556.0
MMD2_k127_4670258_10 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000003109 198.0
MMD2_k127_4670258_13 GtrA-like protein - - - 0.000000000002097 72.0
MMD2_k127_4670258_15 Uncharacterised protein family (UPF0149) - - - 0.0000004238 58.0
MMD2_k127_4670258_16 Gram-negative bacterial TonB protein C-terminal - - - 0.000001567 60.0
MMD2_k127_4670258_2 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 564.0
MMD2_k127_4670258_3 PFAM Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 404.0
MMD2_k127_4670258_4 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 366.0
MMD2_k127_4670258_5 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 317.0
MMD2_k127_4670258_6 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 313.0
MMD2_k127_4670258_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 297.0
MMD2_k127_4670258_8 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003661 253.0
MMD2_k127_4670258_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000003615 225.0
MMD2_k127_4672753_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1070.0
MMD2_k127_4672753_1 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 624.0
MMD2_k127_4672753_10 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000003248 156.0
MMD2_k127_4672753_11 Sporulation related domain - - - 0.0000000000000000000000000000000000008204 147.0
MMD2_k127_4672753_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.00000000000000000000004708 115.0
MMD2_k127_4672753_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 418.0
MMD2_k127_4672753_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 387.0
MMD2_k127_4672753_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 343.0
MMD2_k127_4672753_5 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 323.0
MMD2_k127_4672753_6 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 316.0
MMD2_k127_4672753_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000001043 215.0
MMD2_k127_4672753_8 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000007233 203.0
MMD2_k127_4672753_9 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000002749 168.0
MMD2_k127_4749995_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 493.0
MMD2_k127_4749995_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 395.0
MMD2_k127_4749995_2 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000001879 208.0
MMD2_k127_4749995_3 Conserved TM helix - - - 0.0000000000000000000000000000000000000000002841 169.0
MMD2_k127_4749995_4 MgtE intracellular N domain - - - 0.00000000000000000000000001045 126.0
MMD2_k127_4764924_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 306.0
MMD2_k127_4764924_1 - - - - 0.0000000000000000000000001357 117.0
MMD2_k127_4764924_2 - - - - 0.0000000000002403 80.0
MMD2_k127_4764924_3 Ferredoxin-fold anticodon binding domain K01889 - 6.1.1.20 0.00000001468 60.0
MMD2_k127_4764924_4 Protein of unknown function (DUF805) - - - 0.00000508 54.0
MMD2_k127_4774660_0 ribosomal rna small subunit methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 517.0
MMD2_k127_4774660_1 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000009357 153.0
MMD2_k127_4774660_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000007994 150.0
MMD2_k127_4774660_3 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000002799 60.0
MMD2_k127_4783292_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 2.29e-297 924.0
MMD2_k127_4783292_1 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 578.0
MMD2_k127_4783292_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006878 259.0
MMD2_k127_4783292_3 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000001491 229.0
MMD2_k127_4783292_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.00000000000004723 87.0
MMD2_k127_4783292_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000098 53.0
MMD2_k127_4804105_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 583.0
MMD2_k127_4804105_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 537.0
MMD2_k127_4804105_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
MMD2_k127_4804105_3 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 293.0
MMD2_k127_4804105_4 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000002101 216.0
MMD2_k127_4804105_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000001996 176.0
MMD2_k127_4804105_6 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000000000000000001268 157.0
MMD2_k127_4804105_7 - - - - 0.0000000000000000001587 97.0
MMD2_k127_4804105_8 Protein of unknown function (DUF3106) - - - 0.0000000000000001036 89.0
MMD2_k127_4804105_9 - - - - 0.0000139 52.0
MMD2_k127_4807203_0 Protein of unknown function (DUF3376) - - - 2.107e-232 745.0
MMD2_k127_4807203_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 589.0
MMD2_k127_4807203_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001178 264.0
MMD2_k127_4807203_11 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003167 267.0
MMD2_k127_4807203_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001214 235.0
MMD2_k127_4807203_13 ABC transporter transmembrane region K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000001243 233.0
MMD2_k127_4807203_14 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000004639 222.0
MMD2_k127_4807203_15 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.34 0.0000000000000000000000000000000000000000000000000002131 194.0
MMD2_k127_4807203_16 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000001863 196.0
MMD2_k127_4807203_17 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000001968 156.0
MMD2_k127_4807203_18 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000000000000000000000000000000000169 153.0
MMD2_k127_4807203_19 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000002617 146.0
MMD2_k127_4807203_2 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 568.0
MMD2_k127_4807203_20 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000006068 145.0
MMD2_k127_4807203_21 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000002067 128.0
MMD2_k127_4807203_22 Amidohydrolase family - - - 0.000000000000000000000000002341 116.0
MMD2_k127_4807203_23 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000004451 119.0
MMD2_k127_4807203_24 - - - - 0.0000000000000000006643 101.0
MMD2_k127_4807203_25 Cytochrome c K08738 - - 0.0000000000000000009924 91.0
MMD2_k127_4807203_26 - - - - 0.000000000004343 73.0
MMD2_k127_4807203_27 - - - - 0.000000000006804 78.0
MMD2_k127_4807203_28 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00000000006352 68.0
MMD2_k127_4807203_29 CHRD domain containing protein - - - 0.0000148 54.0
MMD2_k127_4807203_3 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 554.0
MMD2_k127_4807203_4 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 524.0
MMD2_k127_4807203_5 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 486.0
MMD2_k127_4807203_6 G8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 466.0
MMD2_k127_4807203_7 Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins - GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046983,GO:0070566,GO:0070733,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 457.0
MMD2_k127_4807203_8 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 389.0
MMD2_k127_4807203_9 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 308.0
MMD2_k127_4825301_0 ABC transporter transmembrane region K11085 - - 1.279e-221 694.0
MMD2_k127_4825301_1 Alpha/beta hydrolase family K22318 - - 0.00000000000000000000000000000000000000000000000000000000004996 216.0
MMD2_k127_4825301_2 Integron-associated effector binding protein K13652 - - 0.0000000000000000000000000000000000000000006526 163.0
MMD2_k127_4825301_3 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000000008556 154.0
MMD2_k127_4825301_4 Bacterial transcription activator, effector binding domain K13652 - - 0.000000000000000002226 87.0
MMD2_k127_4828951_0 MacB-like periplasmic core domain - - - 2.093e-217 703.0
MMD2_k127_4828951_1 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 595.0
MMD2_k127_4828951_2 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 573.0
MMD2_k127_4828951_3 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 351.0
MMD2_k127_4828951_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 350.0
MMD2_k127_4828951_5 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000005618 236.0
MMD2_k127_4828951_6 - - - - 0.000000000000000000000000000000000000001628 159.0
MMD2_k127_4867002_0 NADPH quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 341.0
MMD2_k127_4867002_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 316.0
MMD2_k127_4867002_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001889 286.0
MMD2_k127_4867002_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000001878 248.0
MMD2_k127_4867002_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000001781 230.0
MMD2_k127_487664_0 chorismate binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 506.0
MMD2_k127_487664_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 337.0
MMD2_k127_487664_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002919 280.0
MMD2_k127_487664_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004933 243.0
MMD2_k127_487664_4 SnoaL-like domain K06893 - - 0.00000000000000000000000000000000000000000615 157.0
MMD2_k127_487664_5 PFAM peptidase M48 Ste24p - - - 0.00000000000000000004242 106.0
MMD2_k127_487664_6 Ankyrin repeat K06867 - - 0.000000004099 67.0
MMD2_k127_487664_7 Plasmid stability protein K21495 - - 0.00000002547 60.0
MMD2_k127_487664_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000002192 58.0
MMD2_k127_4887172_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 415.0
MMD2_k127_4887172_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 301.0
MMD2_k127_4887172_2 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000002365 178.0
MMD2_k127_4887172_3 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000015 160.0
MMD2_k127_4887172_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000003861 136.0
MMD2_k127_4887172_5 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000004241 131.0
MMD2_k127_4887172_6 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000001888 100.0
MMD2_k127_4887172_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000001545 106.0
MMD2_k127_4887172_8 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000003421 87.0
MMD2_k127_4887172_9 MaoC like domain - - - 0.0000000000005245 71.0
MMD2_k127_4909810_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 8.904e-279 865.0
MMD2_k127_4909810_1 Sulfite reductase K00381 - 1.8.1.2 7.748e-233 734.0
MMD2_k127_4909810_10 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 313.0
MMD2_k127_4909810_11 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002073 274.0
MMD2_k127_4909810_12 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009377 262.0
MMD2_k127_4909810_13 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000001703 233.0
MMD2_k127_4909810_14 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000004966 232.0
MMD2_k127_4909810_15 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000001446 239.0
MMD2_k127_4909810_16 Bacterial protein of unknown function (DUF934) - - - 0.000000000000000000000000000000000000000000000001012 179.0
MMD2_k127_4909810_17 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000004437 181.0
MMD2_k127_4909810_18 - - - - 0.000000000000000000000000000000000000000001346 171.0
MMD2_k127_4909810_19 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000000000000000003037 160.0
MMD2_k127_4909810_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 576.0
MMD2_k127_4909810_20 Hsp20/alpha crystallin family - - - 0.00000000000000000000000002486 113.0
MMD2_k127_4909810_21 - - - - 0.0000000000000001338 89.0
MMD2_k127_4909810_22 Protein of unknown function (DUF2849) - - - 0.00000000000461 73.0
MMD2_k127_4909810_23 - - - - 0.000000319 62.0
MMD2_k127_4909810_3 MFS/sugar transport protein K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 533.0
MMD2_k127_4909810_4 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 518.0
MMD2_k127_4909810_5 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 427.0
MMD2_k127_4909810_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 387.0
MMD2_k127_4909810_7 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 374.0
MMD2_k127_4909810_8 malonyl CoA-acyl carrier protein transacylase K00645,K13935 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 314.0
MMD2_k127_4909810_9 D-arabinono-1,4-lactone oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 314.0
MMD2_k127_4932622_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1497.0
MMD2_k127_4932622_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1284.0
MMD2_k127_4932622_10 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 460.0
MMD2_k127_4932622_11 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006961 445.0
MMD2_k127_4932622_12 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 430.0
MMD2_k127_4932622_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 424.0
MMD2_k127_4932622_14 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 402.0
MMD2_k127_4932622_15 Psort location Cytoplasmic, score 8.96 K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 379.0
MMD2_k127_4932622_16 DNA recombination protein RmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 384.0
MMD2_k127_4932622_17 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 365.0
MMD2_k127_4932622_18 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 326.0
MMD2_k127_4932622_19 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 314.0
MMD2_k127_4932622_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1199.0
MMD2_k127_4932622_20 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 323.0
MMD2_k127_4932622_21 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 313.0
MMD2_k127_4932622_22 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 309.0
MMD2_k127_4932622_23 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 298.0
MMD2_k127_4932622_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 302.0
MMD2_k127_4932622_25 regulation of single-species biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 298.0
MMD2_k127_4932622_26 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000328 284.0
MMD2_k127_4932622_27 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001532 263.0
MMD2_k127_4932622_28 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001359 266.0
MMD2_k127_4932622_29 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006281 254.0
MMD2_k127_4932622_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.666e-317 985.0
MMD2_k127_4932622_30 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000004142 239.0
MMD2_k127_4932622_31 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000852 252.0
MMD2_k127_4932622_32 ribonuclease inhibitor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000163 240.0
MMD2_k127_4932622_33 reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001416 251.0
MMD2_k127_4932622_34 haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000005052 204.0
MMD2_k127_4932622_35 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000002583 175.0
MMD2_k127_4932622_36 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000006782 155.0
MMD2_k127_4932622_37 - - - - 0.00000000000000000000000000000000000000008088 166.0
MMD2_k127_4932622_38 acetyltransferase - - - 0.0000000000000000000000000000000000000006238 160.0
MMD2_k127_4932622_39 PFAM RNA recognition motif - - - 0.00000000000000000000000000000006887 132.0
MMD2_k127_4932622_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.455e-272 848.0
MMD2_k127_4932622_40 protein import - - - 0.000000000000000000000000000003864 137.0
MMD2_k127_4932622_41 - - - - 0.0000000000000000000000002294 114.0
MMD2_k127_4932622_42 - - - - 0.0000000000000000000006648 103.0
MMD2_k127_4932622_43 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000003183 90.0
MMD2_k127_4932622_44 SnoaL-like domain - - - 0.0000000000000001036 89.0
MMD2_k127_4932622_45 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000006114 69.0
MMD2_k127_4932622_5 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 514.0
MMD2_k127_4932622_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 504.0
MMD2_k127_4932622_7 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 466.0
MMD2_k127_4932622_8 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 465.0
MMD2_k127_4932622_9 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 494.0
MMD2_k127_4950231_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 511.0
MMD2_k127_4950231_1 Trypsin K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 340.0
MMD2_k127_4950231_2 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 300.0
MMD2_k127_4950231_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006321 286.0
MMD2_k127_4990772_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 317.0
MMD2_k127_4990772_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002114 268.0
MMD2_k127_4990772_2 DJ-1/PfpI family K18199 - 4.2.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000002286 262.0
MMD2_k127_4990772_3 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000656 225.0
MMD2_k127_4990772_4 PFAM Integrase core domain K07497 - - 0.0000000000000000000000000000005867 123.0
MMD2_k127_4990772_6 Cupin 2, conserved barrel domain protein - - - 0.0000006938 56.0
MMD2_k127_4998456_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1177.0
MMD2_k127_4998456_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 570.0
MMD2_k127_4998456_10 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000001073 224.0
MMD2_k127_4998456_11 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
MMD2_k127_4998456_14 CYTH K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000001366 192.0
MMD2_k127_4998456_15 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000001064 181.0
MMD2_k127_4998456_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000297 177.0
MMD2_k127_4998456_17 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000000000000000002539 179.0
MMD2_k127_4998456_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000004043 165.0
MMD2_k127_4998456_19 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.0000000000000000000000000000000000001046 150.0
MMD2_k127_4998456_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 481.0
MMD2_k127_4998456_20 FtsX-like permease family K02004 - - 0.00000000000000000000000000000003141 133.0
MMD2_k127_4998456_21 Belongs to the GST superfamily K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0044424,GO:0044464,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.00000000000000000000000000003952 122.0
MMD2_k127_4998456_22 AraC-binding-like domain - - - 0.000000000000000000000003245 115.0
MMD2_k127_4998456_23 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000001988 101.0
MMD2_k127_4998456_24 Putative diguanylate phosphodiesterase - - - 0.0000000000000000663 92.0
MMD2_k127_4998456_25 Peptidoglycan-binding protein, CsiV - - - 0.000000000000002082 85.0
MMD2_k127_4998456_26 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000139 79.0
MMD2_k127_4998456_27 Protein of unknown function (DUF1289) - - - 0.00000000002738 67.0
MMD2_k127_4998456_28 Belongs to the GST superfamily K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0044424,GO:0044464,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.00006289 46.0
MMD2_k127_4998456_3 Retinal pigment epithelial membrane protein K11159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 380.0
MMD2_k127_4998456_4 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 348.0
MMD2_k127_4998456_5 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 289.0
MMD2_k127_4998456_6 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004939 282.0
MMD2_k127_4998456_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000004953 250.0
MMD2_k127_4998456_8 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000936 224.0
MMD2_k127_4998456_9 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000001248 228.0
MMD2_k127_5074928_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.451e-315 995.0
MMD2_k127_5074928_1 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 1.482e-240 770.0
MMD2_k127_5074928_10 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000001375 222.0
MMD2_k127_5074928_11 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000009002 219.0
MMD2_k127_5074928_12 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 0.0000000000000000000000000000000000000000000000000000008375 196.0
MMD2_k127_5074928_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000002103 199.0
MMD2_k127_5074928_14 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000002383 201.0
MMD2_k127_5074928_15 - - - - 0.00000000000000000000000000000000000000000000000000178 183.0
MMD2_k127_5074928_16 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000001804 192.0
MMD2_k127_5074928_17 Phosphoserine phosphatase - - - 0.000000000000000000000000000000000000000000000001565 190.0
MMD2_k127_5074928_18 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000001026 181.0
MMD2_k127_5074928_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000001088 176.0
MMD2_k127_5074928_2 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 608.0
MMD2_k127_5074928_20 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000002284 162.0
MMD2_k127_5074928_21 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000001683 166.0
MMD2_k127_5074928_22 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000005927 159.0
MMD2_k127_5074928_23 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000001022 167.0
MMD2_k127_5074928_24 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000004432 151.0
MMD2_k127_5074928_25 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000008097 153.0
MMD2_k127_5074928_26 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000001077 162.0
MMD2_k127_5074928_27 - - - - 0.0000000000000000000000000005652 124.0
MMD2_k127_5074928_28 - - - - 0.0000000000000000000000000009162 126.0
MMD2_k127_5074928_29 Cytochrome C' - - - 0.000000000000000000000000001101 120.0
MMD2_k127_5074928_3 Bacterial protein of unknown function (DUF839) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 585.0
MMD2_k127_5074928_30 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000009575 120.0
MMD2_k127_5074928_31 - - - - 0.0000000000000000000008345 110.0
MMD2_k127_5074928_32 Sporulation related domain - - - 0.0000000000003864 80.0
MMD2_k127_5074928_4 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 541.0
MMD2_k127_5074928_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 390.0
MMD2_k127_5074928_6 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 358.0
MMD2_k127_5074928_7 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 343.0
MMD2_k127_5074928_8 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000003565 249.0
MMD2_k127_5074928_9 TipAS antibiotic-recognition domain K21744 - - 0.0000000000000000000000000000000000000000000000000000000000000008089 228.0
MMD2_k127_5078222_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 390.0
MMD2_k127_5078222_1 TAP-like protein K22250 - 3.1.1.76 0.000000000000000000000000000000000000000000000000000009039 201.0
MMD2_k127_5078222_2 poly(R)-hydroxyalkanoic acid synthase K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000000000000000000000000000000009379 169.0
MMD2_k127_508487_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 550.0
MMD2_k127_508487_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 497.0
MMD2_k127_508487_10 Oxalate decarboxylase - - - 0.000000000000000000000000000000000000000002985 158.0
MMD2_k127_508487_11 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000000000000000004061 149.0
MMD2_k127_508487_12 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000003079 138.0
MMD2_k127_508487_13 mandelate racemase muconate lactonizing - - - 0.00000000000000000000000000008337 130.0
MMD2_k127_508487_14 Phospholipid methyltransferase - - - 0.000000000000000000000000001829 125.0
MMD2_k127_508487_15 PFAM Helix-turn-helix - - - 0.000000000000000000000000006206 115.0
MMD2_k127_508487_16 - - - - 0.00000000000000000000001395 105.0
MMD2_k127_508487_17 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000106 92.0
MMD2_k127_508487_18 - - - - 0.0000000000000004244 90.0
MMD2_k127_508487_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 440.0
MMD2_k127_508487_20 - - - - 0.000001045 61.0
MMD2_k127_508487_21 - - - - 0.000001073 62.0
MMD2_k127_508487_22 ORF6N domain - - - 0.0006317 43.0
MMD2_k127_508487_3 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 325.0
MMD2_k127_508487_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003356 289.0
MMD2_k127_508487_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009524 252.0
MMD2_k127_508487_6 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001226 244.0
MMD2_k127_508487_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000006438 226.0
MMD2_k127_508487_8 Staphylococcal nuclease homologues K16561 - - 0.0000000000000000000000000000000000000000000000000000000000005199 219.0
MMD2_k127_508487_9 cellulase activity - - - 0.00000000000000000000000000000000000000000005003 179.0
MMD2_k127_5141744_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.943e-229 722.0
MMD2_k127_5141744_1 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 590.0
MMD2_k127_5141744_10 Thioredoxin-like - - - 0.0000000000000001566 87.0
MMD2_k127_5141744_11 Protein of unknown function (DUF4019) - - - 0.0000000000003049 78.0
MMD2_k127_5141744_2 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 583.0
MMD2_k127_5141744_3 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 372.0
MMD2_k127_5141744_4 PFAM Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 321.0
MMD2_k127_5141744_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 295.0
MMD2_k127_5141744_6 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001742 247.0
MMD2_k127_5141744_7 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000001153 235.0
MMD2_k127_5141744_8 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000005812 200.0
MMD2_k127_5141744_9 Acetyltransferase (GNAT) domain K03817 - - 0.0000000000000000000000000000000000000000000000000407 184.0
MMD2_k127_51910_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 2.649e-237 746.0
MMD2_k127_51910_1 PFAM AMP-dependent synthetase and ligase K00666 - - 5.24e-221 700.0
MMD2_k127_51910_10 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 353.0
MMD2_k127_51910_11 Amidohydrolase K22213 - 4.1.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 308.0
MMD2_k127_51910_12 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000952 240.0
MMD2_k127_51910_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000004346 232.0
MMD2_k127_51910_14 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000008605 228.0
MMD2_k127_51910_15 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000004548 179.0
MMD2_k127_51910_16 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000004627 165.0
MMD2_k127_51910_17 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000001236 163.0
MMD2_k127_51910_18 - - - - 0.000000000000000000000000000000000001843 151.0
MMD2_k127_51910_19 Protein kinase domain - - - 0.00000000000000000000000000000002917 144.0
MMD2_k127_51910_2 MacB-like periplasmic core domain - - - 2.899e-218 704.0
MMD2_k127_51910_20 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000004235 132.0
MMD2_k127_51910_21 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000001257 115.0
MMD2_k127_51910_22 Phospholipid methyltransferase - - - 0.000000000000000000000000006937 119.0
MMD2_k127_51910_23 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000006076 117.0
MMD2_k127_51910_24 Acid phosphatase homologues - - - 0.000000000000000000000001556 114.0
MMD2_k127_51910_25 - - - - 0.000000000000000000000005888 112.0
MMD2_k127_51910_26 - - - - 0.00000000005917 69.0
MMD2_k127_51910_27 SnoaL-like domain - - - 0.0000000001655 72.0
MMD2_k127_51910_29 domain, Protein K20276 - - 0.000003982 53.0
MMD2_k127_51910_3 Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 538.0
MMD2_k127_51910_4 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 486.0
MMD2_k127_51910_5 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 455.0
MMD2_k127_51910_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 430.0
MMD2_k127_51910_7 Dehydrogenase E1 component K00161,K00166,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 424.0
MMD2_k127_51910_8 Sugar (and other) transporter K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 404.0
MMD2_k127_51910_9 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 372.0
MMD2_k127_5198060_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 7.721e-296 925.0
MMD2_k127_5198060_1 TonB dependent receptor K02014 - - 9.64e-235 750.0
MMD2_k127_5198060_2 Bacterial extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 453.0
MMD2_k127_5198060_3 ATPase activity K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 413.0
MMD2_k127_5198060_4 Binding-protein-dependent transport system inner membrane component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 336.0
MMD2_k127_5198060_5 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 328.0
MMD2_k127_5198060_6 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007605 269.0
MMD2_k127_5198060_7 PFAM binding-protein-dependent transport systems inner membrane component K02047 - - 0.000000000000000000000000000000000000000000000000000000000001578 226.0
MMD2_k127_5230936_0 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 616.0
MMD2_k127_5230936_1 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 372.0
MMD2_k127_5230936_10 Phosphoglycerate mutase family - - - 0.00000000001501 73.0
MMD2_k127_5230936_11 Protein of unknown function (DUF2384) - - - 0.000000000594 66.0
MMD2_k127_5230936_13 CopC domain K07156,K14166 - - 0.0000000121 61.0
MMD2_k127_5230936_16 Metallo-beta-lactamase superfamily - - - 0.00005941 48.0
MMD2_k127_5230936_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 314.0
MMD2_k127_5230936_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001284 230.0
MMD2_k127_5230936_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000005006 196.0
MMD2_k127_5230936_5 Domain of unknown function (DUF2703) - - - 0.000000000000000000000000000000000000000000001147 169.0
MMD2_k127_5230936_6 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000158 138.0
MMD2_k127_5230936_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000003395 143.0
MMD2_k127_5230936_8 Copper resistance protein D K07245 - - 0.00000000000000000000000000003438 128.0
MMD2_k127_5230936_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000004263 100.0
MMD2_k127_527000_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 589.0
MMD2_k127_527000_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 452.0
MMD2_k127_527000_10 FAD binding domain K03391,K05712 - 1.14.13.127,1.14.13.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 327.0
MMD2_k127_527000_11 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002232 293.0
MMD2_k127_527000_12 helix_turn_helix, Lux Regulon K07693 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007167 273.0
MMD2_k127_527000_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000398 265.0
MMD2_k127_527000_14 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004169 265.0
MMD2_k127_527000_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003212 232.0
MMD2_k127_527000_16 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000008619 219.0
MMD2_k127_527000_17 Histidine kinase K07778 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000386 208.0
MMD2_k127_527000_18 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000008536 194.0
MMD2_k127_527000_19 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000008543 199.0
MMD2_k127_527000_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 417.0
MMD2_k127_527000_20 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000184 182.0
MMD2_k127_527000_21 - - - - 0.00000000000000000000000000000000000000000034 177.0
MMD2_k127_527000_22 - - - - 0.0000000000000000000000000000000000000000008542 169.0
MMD2_k127_527000_23 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000005905 166.0
MMD2_k127_527000_24 - K06148 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.00000000000000000000000000000000000000227 154.0
MMD2_k127_527000_25 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000001692 159.0
MMD2_k127_527000_26 Cro/C1-type HTH DNA-binding domain K07727 - - 0.000000000000000000000000002549 113.0
MMD2_k127_527000_27 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000224 110.0
MMD2_k127_527000_28 COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit - - - 0.000000000000000006816 88.0
MMD2_k127_527000_3 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 412.0
MMD2_k127_527000_30 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000007175 64.0
MMD2_k127_527000_31 - - - - 0.000007034 55.0
MMD2_k127_527000_32 Protein of unknown function (DUF2975) - - - 0.00001738 55.0
MMD2_k127_527000_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 394.0
MMD2_k127_527000_5 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 374.0
MMD2_k127_527000_6 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 376.0
MMD2_k127_527000_7 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 356.0
MMD2_k127_527000_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 344.0
MMD2_k127_527000_9 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 330.0
MMD2_k127_5391270_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.67e-237 742.0
MMD2_k127_5391270_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.879e-233 736.0
MMD2_k127_5391270_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 428.0
MMD2_k127_5391270_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 424.0
MMD2_k127_5391270_4 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 336.0
MMD2_k127_5391270_5 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000001311 220.0
MMD2_k127_5391270_6 - - - - 0.00000000000000000000000000000000000000000000000000000003508 212.0
MMD2_k127_5391270_7 Putative restriction endonuclease - - - 0.0000003772 53.0
MMD2_k127_5419734_0 Dehydrogenase K00117 - 1.1.5.2 2.332e-281 882.0
MMD2_k127_5419734_1 efflux transmembrane transporter activity - - - 8.782e-231 742.0
MMD2_k127_5419734_10 - - - - 0.00000000000000000000000000000007396 132.0
MMD2_k127_5419734_11 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000006093 110.0
MMD2_k127_5419734_12 Amidohydrolase family - - - 0.00000000000000000000008418 112.0
MMD2_k127_5419734_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 434.0
MMD2_k127_5419734_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 382.0
MMD2_k127_5419734_4 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 314.0
MMD2_k127_5419734_5 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002631 276.0
MMD2_k127_5419734_6 extracellular solute-binding protein, family 1 K22003 - 5.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000004943 262.0
MMD2_k127_5419734_8 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000001086 182.0
MMD2_k127_5419734_9 - - - - 0.00000000000000000000000000000000000000000000001332 176.0
MMD2_k127_5420342_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.574e-288 899.0
MMD2_k127_5420342_1 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 2.089e-271 899.0
MMD2_k127_5420342_10 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 383.0
MMD2_k127_5420342_11 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 398.0
MMD2_k127_5420342_12 Oxidoreductase FAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009909 364.0
MMD2_k127_5420342_13 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 358.0
MMD2_k127_5420342_14 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 344.0
MMD2_k127_5420342_15 Negative regulator of beta-lactamase expression K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000001545 243.0
MMD2_k127_5420342_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000001303 231.0
MMD2_k127_5420342_17 adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000001497 228.0
MMD2_k127_5420342_18 response regulator receiver K02657 - - 0.0000000000000000000000000000000000000000000000000000000000002021 214.0
MMD2_k127_5420342_19 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000003296 216.0
MMD2_k127_5420342_2 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 566.0
MMD2_k127_5420342_20 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000542 215.0
MMD2_k127_5420342_21 - - - - 0.00000000000000000000000000000000000000000000000000000003872 207.0
MMD2_k127_5420342_22 Iron--sulfur cluster insertion protein erpA K15724 - - 0.000000000000000000000000000000000000000000000000008341 182.0
MMD2_k127_5420342_23 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000002651 185.0
MMD2_k127_5420342_24 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000001152 181.0
MMD2_k127_5420342_25 response regulator receiver K02658 - - 0.000000000000000000000000000000000000000004809 164.0
MMD2_k127_5420342_26 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000004429 143.0
MMD2_k127_5420342_27 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000005529 132.0
MMD2_k127_5420342_28 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000006354 133.0
MMD2_k127_5420342_29 Domain of unknown function (DUF4426) - - - 0.000000000000000000000000000004977 126.0
MMD2_k127_5420342_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 566.0
MMD2_k127_5420342_30 integral membrane protein K02221 - - 0.0000000000000000000000000004128 120.0
MMD2_k127_5420342_31 - - - - 0.0000000000000000000000004275 115.0
MMD2_k127_5420342_33 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000007533 101.0
MMD2_k127_5420342_34 Two component signalling adaptor domain K06598 - - 0.000000000000000000107 95.0
MMD2_k127_5420342_35 - - - - 0.0000000000002109 69.0
MMD2_k127_5420342_36 - - - - 0.00000000003233 65.0
MMD2_k127_5420342_4 twitching motility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 532.0
MMD2_k127_5420342_5 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 504.0
MMD2_k127_5420342_6 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 424.0
MMD2_k127_5420342_7 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 425.0
MMD2_k127_5420342_8 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 424.0
MMD2_k127_5420342_9 COG0840 Methyl-accepting chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 400.0
MMD2_k127_542838_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1298.0
MMD2_k127_542838_1 Tetratricopeptide repeat - - - 4.228e-234 756.0
MMD2_k127_542838_10 ATPase activity K02013,K05776 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005358 288.0
MMD2_k127_542838_11 Inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000005598 263.0
MMD2_k127_542838_12 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004294 255.0
MMD2_k127_542838_13 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000202 244.0
MMD2_k127_542838_14 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000004397 226.0
MMD2_k127_542838_15 - - - - 0.00000000000000000000000000000000000000000000000000000001855 203.0
MMD2_k127_542838_16 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000002604 198.0
MMD2_k127_542838_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000003004 197.0
MMD2_k127_542838_18 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000472 180.0
MMD2_k127_542838_19 Thioredoxin-like - - - 0.000000000000000000000000000000000000002928 151.0
MMD2_k127_542838_2 Ammonium transporter K03320 - - 2.312e-227 711.0
MMD2_k127_542838_20 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000009311 130.0
MMD2_k127_542838_21 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000007258 125.0
MMD2_k127_542838_22 FOG TPR repeat - - - 0.0000000000000000000000000001484 125.0
MMD2_k127_542838_23 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000004926 105.0
MMD2_k127_542838_24 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000279 104.0
MMD2_k127_542838_25 - - - - 0.0000000000000167 80.0
MMD2_k127_542838_26 MerC mercury resistance protein - - - 0.00000000002691 72.0
MMD2_k127_542838_3 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 574.0
MMD2_k127_542838_4 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 468.0
MMD2_k127_542838_5 transporter K08195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 431.0
MMD2_k127_542838_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 430.0
MMD2_k127_542838_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 329.0
MMD2_k127_542838_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 322.0
MMD2_k127_542838_9 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 290.0
MMD2_k127_5429282_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.3e-239 747.0
MMD2_k127_5429282_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 5.216e-204 645.0
MMD2_k127_5429282_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 378.0
MMD2_k127_5429282_11 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 329.0
MMD2_k127_5429282_12 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 314.0
MMD2_k127_5429282_13 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002185 276.0
MMD2_k127_5429282_14 COG3202 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004703 262.0
MMD2_k127_5429282_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003315 258.0
MMD2_k127_5429282_16 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001146 255.0
MMD2_k127_5429282_17 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000002638 206.0
MMD2_k127_5429282_18 PFAM MucB RseB K03598 - - 0.000000000000000000000000000000000000000000000000000118 204.0
MMD2_k127_5429282_19 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000004047 186.0
MMD2_k127_5429282_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 497.0
MMD2_k127_5429282_20 Gluconokinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000001757 188.0
MMD2_k127_5429282_21 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000002848 180.0
MMD2_k127_5429282_22 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000002554 144.0
MMD2_k127_5429282_23 - - - - 0.00000000000000000000000000000000000002949 148.0
MMD2_k127_5429282_24 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000616 108.0
MMD2_k127_5429282_25 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.000000000000002461 76.0
MMD2_k127_5429282_26 cell redox homeostasis K00384 - 1.8.1.9 0.00000000000009827 78.0
MMD2_k127_5429282_27 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000004221 73.0
MMD2_k127_5429282_28 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000007165 60.0
MMD2_k127_5429282_29 Positive regulator of sigma(E), RseC/MucC - - - 0.000001474 57.0
MMD2_k127_5429282_3 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 475.0
MMD2_k127_5429282_30 cell adhesion - - - 0.00001106 55.0
MMD2_k127_5429282_31 Anti sigma-E protein RseA, N-terminal domain - - - 0.00006585 52.0
MMD2_k127_5429282_4 helix_turn _helix lactose operon repressor K06145 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 462.0
MMD2_k127_5429282_5 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 434.0
MMD2_k127_5429282_6 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 426.0
MMD2_k127_5429282_7 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 425.0
MMD2_k127_5429282_8 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 378.0
MMD2_k127_5429282_9 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 371.0
MMD2_k127_5443585_0 DNA helicase K03654 - 3.6.4.12 7.71e-253 793.0
MMD2_k127_5443585_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.013e-233 767.0
MMD2_k127_5443585_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 352.0
MMD2_k127_5443585_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 338.0
MMD2_k127_5443585_12 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 338.0
MMD2_k127_5443585_13 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 332.0
MMD2_k127_5443585_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 322.0
MMD2_k127_5443585_15 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 293.0
MMD2_k127_5443585_16 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007569 270.0
MMD2_k127_5443585_17 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004528 266.0
MMD2_k127_5443585_18 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003572 257.0
MMD2_k127_5443585_19 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000001579 244.0
MMD2_k127_5443585_2 Dehydrogenase K00117 - 1.1.5.2 4.985e-209 674.0
MMD2_k127_5443585_20 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001636 246.0
MMD2_k127_5443585_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002197 232.0
MMD2_k127_5443585_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000002846 231.0
MMD2_k127_5443585_23 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000000001725 234.0
MMD2_k127_5443585_24 ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.0000000000000000000000000000000000000000000000000000000000389 214.0
MMD2_k127_5443585_26 protein conserved in bacteria K09966 - - 0.000000000000000000000000000000000000000000000000000000009142 200.0
MMD2_k127_5443585_27 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000002774 184.0
MMD2_k127_5443585_28 TPM domain K08988 - - 0.000000000000000000000000000000000000000000009984 167.0
MMD2_k127_5443585_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000181 166.0
MMD2_k127_5443585_3 PQQ enzyme repeat - - - 6.916e-209 671.0
MMD2_k127_5443585_30 lactoylglutathione lyase activity K03088 - - 0.0000000000000000000000000000000000004554 151.0
MMD2_k127_5443585_31 Predicted membrane protein (DUF2306) - - - 0.000000000000000000000000000000009574 136.0
MMD2_k127_5443585_32 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000005125 139.0
MMD2_k127_5443585_33 - - - - 0.000000000000000000000000000005572 133.0
MMD2_k127_5443585_34 Phospholipid methyltransferase - - - 0.000000000000000000000000000005958 135.0
MMD2_k127_5443585_35 - - - - 0.000000000000000000000000001736 127.0
MMD2_k127_5443585_36 ATPase activity K01990 - - 0.000000000000000000006591 100.0
MMD2_k127_5443585_37 - - - - 0.0000000000001483 80.0
MMD2_k127_5443585_39 - - - - 0.00000000004843 70.0
MMD2_k127_5443585_4 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 630.0
MMD2_k127_5443585_40 metallopeptidase activity K20276 - - 0.00002901 56.0
MMD2_k127_5443585_5 DNA topological change K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 589.0
MMD2_k127_5443585_6 Belongs to the GMC oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 534.0
MMD2_k127_5443585_7 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 437.0
MMD2_k127_5443585_8 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 385.0
MMD2_k127_5443585_9 Putative ABC exporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 354.0
MMD2_k127_5509297_0 Efflux pump membrane transporter K18138 - - 0.0 1150.0
MMD2_k127_5509297_1 Short branched chain specific acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 597.0
MMD2_k127_5509297_10 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000001721 129.0
MMD2_k127_5509297_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000008588 92.0
MMD2_k127_5509297_12 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000004603 53.0
MMD2_k127_5509297_2 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 533.0
MMD2_k127_5509297_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 454.0
MMD2_k127_5509297_4 LysR substrate binding domain K18900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 387.0
MMD2_k127_5509297_5 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 400.0
MMD2_k127_5509297_6 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 347.0
MMD2_k127_5509297_7 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001446 292.0
MMD2_k127_5509297_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005216 279.0
MMD2_k127_5509297_9 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000002521 217.0
MMD2_k127_5530062_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.367e-311 964.0
MMD2_k127_5530062_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.674e-274 862.0
MMD2_k127_5530062_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002615 267.0
MMD2_k127_5530062_11 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000008524 247.0
MMD2_k127_5530062_12 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000001699 237.0
MMD2_k127_5530062_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000001838 209.0
MMD2_k127_5530062_14 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000001093 192.0
MMD2_k127_5530062_15 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000603 196.0
MMD2_k127_5530062_16 protein conserved in bacteria K09973 - - 0.0000000000000000000000000000000000000000000000001234 197.0
MMD2_k127_5530062_17 peptidase S16, lon K07157 - - 0.0000000000000000000000000000000000000000001262 166.0
MMD2_k127_5530062_18 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000002326 105.0
MMD2_k127_5530062_19 - - - - 0.0000000003034 68.0
MMD2_k127_5530062_2 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 9.486e-230 732.0
MMD2_k127_5530062_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.017e-211 664.0
MMD2_k127_5530062_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 546.0
MMD2_k127_5530062_5 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 552.0
MMD2_k127_5530062_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 529.0
MMD2_k127_5530062_7 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 499.0
MMD2_k127_5530062_8 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 394.0
MMD2_k127_5530062_9 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 376.0
MMD2_k127_5538116_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 3.246e-319 999.0
MMD2_k127_5538116_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.373e-299 945.0
MMD2_k127_5538116_10 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576,K22067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 329.0
MMD2_k127_5538116_11 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001024 281.0
MMD2_k127_5538116_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002574 273.0
MMD2_k127_5538116_13 ANTAR K07183 - - 0.0000000000000000000000000000000000000000000000000000000000000003609 241.0
MMD2_k127_5538116_14 Signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000341 224.0
MMD2_k127_5538116_15 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000000000001111 199.0
MMD2_k127_5538116_16 dehydratase - - - 0.00000000000000000000000000000000000000000000000005856 190.0
MMD2_k127_5538116_2 ABC transporter K02049,K15555,K15578 - - 1.089e-246 773.0
MMD2_k127_5538116_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576,K22067 - - 6.945e-225 715.0
MMD2_k127_5538116_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.244e-207 655.0
MMD2_k127_5538116_5 Mo-co oxidoreductase dimerisation domain K17225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 505.0
MMD2_k127_5538116_6 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 486.0
MMD2_k127_5538116_7 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 456.0
MMD2_k127_5538116_8 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 423.0
MMD2_k127_5538116_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 372.0
MMD2_k127_5571499_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1119.0
MMD2_k127_5571499_1 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 4.092e-300 926.0
MMD2_k127_5571499_10 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 414.0
MMD2_k127_5571499_11 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 361.0
MMD2_k127_5571499_12 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 330.0
MMD2_k127_5571499_13 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 270.0
MMD2_k127_5571499_14 - - - - 0.00000000000000000000000000000000000000000000000000000000004076 215.0
MMD2_k127_5571499_15 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000003257 207.0
MMD2_k127_5571499_16 lactoylglutathione lyase activity K03088 - - 0.00000000000000000000000000000000000000000000000000007651 197.0
MMD2_k127_5571499_17 arsenate reductase K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000000000002939 150.0
MMD2_k127_5571499_18 Pilin (bacterial filament) K02650,K02655 - - 0.00000000000000000000000000000000000005376 154.0
MMD2_k127_5571499_19 Nitrite reductase K00363 - 1.7.1.15 0.000000000000000000000000000000003977 135.0
MMD2_k127_5571499_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 7.459e-241 754.0
MMD2_k127_5571499_20 - - - - 0.0000000000000000000000000000001039 139.0
MMD2_k127_5571499_21 Transcriptional regulator - - - 0.0000000000000000001225 94.0
MMD2_k127_5571499_23 - - - - 0.00000000000004508 80.0
MMD2_k127_5571499_24 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000002366 74.0
MMD2_k127_5571499_25 response to abiotic stimulus K06867 - - 0.0000000007282 68.0
MMD2_k127_5571499_26 - - - - 0.00000009772 61.0
MMD2_k127_5571499_27 Protein of unknown function (DUF1697) - - - 0.0001504 52.0
MMD2_k127_5571499_28 prostaglandin-D synthase activity K04097 GO:0000287,GO:0001516,GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0004667,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006518,GO:0006575,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0006749,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008285,GO:0008610,GO:0009058,GO:0009636,GO:0009987,GO:0016053,GO:0016209,GO:0016491,GO:0016684,GO:0016740,GO:0016765,GO:0016853,GO:0016860,GO:0019752,GO:0032787,GO:0033559,GO:0034641,GO:0042127,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046456,GO:0046457,GO:0046872,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051239,GO:0051241,GO:0051716,GO:0055114,GO:0065007,GO:0070887,GO:0071704,GO:0072330,GO:0097237,GO:0098754,GO:0098869,GO:1901564,GO:1901568,GO:1901570,GO:1901576,GO:1905936,GO:1905937,GO:1990748,GO:2000241,GO:2000242,GO:2000254,GO:2000255 2.5.1.18,5.3.99.2 0.0008612 50.0
MMD2_k127_5571499_3 Glycosyl hydrolases family 15 - - - 1.604e-232 736.0
MMD2_k127_5571499_4 PQQ enzyme repeat K00117 - 1.1.5.2 7.155e-199 643.0
MMD2_k127_5571499_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 623.0
MMD2_k127_5571499_6 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 491.0
MMD2_k127_5571499_7 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 488.0
MMD2_k127_5571499_8 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 477.0
MMD2_k127_5571499_9 COG0471 Di- and tricarboxylate transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 454.0
MMD2_k127_5582097_0 Dehydrogenase K00114 - 1.1.2.8 4.444e-207 661.0
MMD2_k127_5582097_1 Dehydrogenase K00114 - 1.1.2.8 2.457e-196 628.0
MMD2_k127_5582097_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001059 275.0
MMD2_k127_5582097_3 - - - - 0.00000000000000000000000000000000000000000000000000000000002049 224.0
MMD2_k127_5582097_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000001007 106.0
MMD2_k127_5582097_5 AraC-binding-like domain - - - 0.0000000000000000000004792 108.0
MMD2_k127_5582097_6 - - - - 0.000000000000000002503 96.0
MMD2_k127_5584097_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1562.0
MMD2_k127_5584097_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.272e-304 945.0
MMD2_k127_5584097_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 485.0
MMD2_k127_5584097_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 306.0
MMD2_k127_5584097_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 291.0
MMD2_k127_5584097_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001968 275.0
MMD2_k127_5584097_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000126 259.0
MMD2_k127_5584097_15 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000008678 245.0
MMD2_k127_5584097_16 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
MMD2_k127_5584097_17 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000001953 220.0
MMD2_k127_5584097_18 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000004284 219.0
MMD2_k127_5584097_19 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000001213 203.0
MMD2_k127_5584097_2 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 6.842e-277 865.0
MMD2_k127_5584097_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000002004 174.0
MMD2_k127_5584097_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000003503 149.0
MMD2_k127_5584097_22 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000003036 94.0
MMD2_k127_5584097_23 - - - - 0.0000000007086 61.0
MMD2_k127_5584097_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.102e-249 772.0
MMD2_k127_5584097_4 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 8.476e-230 736.0
MMD2_k127_5584097_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 8.835e-228 714.0
MMD2_k127_5584097_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.403e-198 626.0
MMD2_k127_5584097_7 carbamoyl-phosphate synthetase glutamine chain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 535.0
MMD2_k127_5584097_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 529.0
MMD2_k127_5584097_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 529.0
MMD2_k127_5593623_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1138.0
MMD2_k127_5593623_1 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 8.244e-307 947.0
MMD2_k127_5593623_10 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 388.0
MMD2_k127_5593623_11 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 360.0
MMD2_k127_5593623_12 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 323.0
MMD2_k127_5593623_13 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 305.0
MMD2_k127_5593623_14 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 301.0
MMD2_k127_5593623_15 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 295.0
MMD2_k127_5593623_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 287.0
MMD2_k127_5593623_17 Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001728 274.0
MMD2_k127_5593623_18 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000003509 259.0
MMD2_k127_5593623_19 PFAM PspA IM30 family protein K03969 GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000003601 239.0
MMD2_k127_5593623_2 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 1.086e-274 866.0
MMD2_k127_5593623_20 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000002337 235.0
MMD2_k127_5593623_21 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000002631 221.0
MMD2_k127_5593623_22 PFAM cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000002421 214.0
MMD2_k127_5593623_23 Cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000449 209.0
MMD2_k127_5593623_24 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000002064 193.0
MMD2_k127_5593623_25 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000003185 190.0
MMD2_k127_5593623_26 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000004972 179.0
MMD2_k127_5593623_27 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000007815 178.0
MMD2_k127_5593623_28 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000167 184.0
MMD2_k127_5593623_29 Transfers electrons from cytochrome c551 to cytochrome oxidase - - - 0.00000000000000000000000000000000000000000002614 165.0
MMD2_k127_5593623_3 oligopeptide transporter - - - 1.44e-217 699.0
MMD2_k127_5593623_30 Domain of unknown function (DUF4399) - - - 0.0000000000000000000000000000000000000000001107 164.0
MMD2_k127_5593623_31 Small integral membrane protein - - - 0.000000000000000000000000000000004648 131.0
MMD2_k127_5593623_32 PspC domain - - - 0.000000000000000000000000073 111.0
MMD2_k127_5593623_33 Tetratricopeptide repeat - - - 0.00000000000000000000002047 103.0
MMD2_k127_5593623_34 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000004657 99.0
MMD2_k127_5593623_35 Phage shock protein B K03970 - - 0.0000000000000008412 79.0
MMD2_k127_5593623_36 Type II secretion system protein B - - - 0.000000000000001203 86.0
MMD2_k127_5593623_37 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000005588 74.0
MMD2_k127_5593623_38 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000008086 75.0
MMD2_k127_5593623_39 - - - - 0.00001675 50.0
MMD2_k127_5593623_4 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 539.0
MMD2_k127_5593623_40 PFAM Flagellar transcriptional activator (FlhC) - - - 0.0007529 49.0
MMD2_k127_5593623_5 Aminotransferase class-V K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 482.0
MMD2_k127_5593623_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 471.0
MMD2_k127_5593623_7 Sigma-54 interaction domain K03974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 412.0
MMD2_k127_5593623_8 COG1131 ABC-type multidrug transport system, ATPase component K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 406.0
MMD2_k127_5593623_9 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 406.0
MMD2_k127_5594398_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 433.0
MMD2_k127_5594398_1 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000003163 192.0
MMD2_k127_5594398_2 AAA-like domain - - - 0.000000000000000000000000000000000000000000000000005424 209.0
MMD2_k127_5594398_3 - - - - 0.000000126 56.0
MMD2_k127_5600565_0 Efflux pump membrane transporter K18299 - - 0.0 1442.0
MMD2_k127_5600565_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1403.0
MMD2_k127_5600565_10 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 464.0
MMD2_k127_5600565_11 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 436.0
MMD2_k127_5600565_12 PFAM PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 393.0
MMD2_k127_5600565_13 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 394.0
MMD2_k127_5600565_14 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 378.0
MMD2_k127_5600565_15 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 387.0
MMD2_k127_5600565_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 359.0
MMD2_k127_5600565_17 Dihydroorotate dehydrogenase K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 330.0
MMD2_k127_5600565_18 Transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 298.0
MMD2_k127_5600565_19 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003985 260.0
MMD2_k127_5600565_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1077.0
MMD2_k127_5600565_20 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000004918 232.0
MMD2_k127_5600565_21 COG0477 Permeases of the major facilitator superfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000144 236.0
MMD2_k127_5600565_22 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000009698 197.0
MMD2_k127_5600565_23 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000002947 171.0
MMD2_k127_5600565_24 CBS domain - - - 0.00000000000000000000000000000000000000000002083 165.0
MMD2_k127_5600565_25 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000004056 167.0
MMD2_k127_5600565_26 - - - - 0.000000000000000000000000000000000000001301 164.0
MMD2_k127_5600565_27 YCII-related domain - - - 0.000000000000000000000000000000000004251 140.0
MMD2_k127_5600565_28 - - - - 0.00000000000000000000000000000004708 129.0
MMD2_k127_5600565_29 cellulase activity K01224,K01729 - 3.2.1.89,4.2.2.3 0.0000000000000000000000006183 122.0
MMD2_k127_5600565_3 efflux transmembrane transporter activity - - - 3.968e-244 818.0
MMD2_k127_5600565_30 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000713 107.0
MMD2_k127_5600565_31 - - - - 0.00000000000000000208 95.0
MMD2_k127_5600565_4 MacB-like periplasmic core domain - - - 2.552e-227 733.0
MMD2_k127_5600565_5 ABC-type antimicrobial peptide transport system, permease component - - - 6.277e-227 728.0
MMD2_k127_5600565_6 Peptidase family M28 - - - 8.428e-220 695.0
MMD2_k127_5600565_7 MacB-like periplasmic core domain - - - 1.511e-215 698.0
MMD2_k127_5600565_8 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 595.0
MMD2_k127_5600565_9 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 575.0
MMD2_k127_5606036_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 518.0
MMD2_k127_5606036_1 alcohol dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 455.0
MMD2_k127_5606036_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000004897 154.0
MMD2_k127_5606036_3 Diguanylate cyclase - - - 0.00000000002012 74.0
MMD2_k127_5606036_4 Iron dependent repressor, N-terminal DNA binding domain - - - 0.00008896 51.0
MMD2_k127_5610952_0 Thiamine pyrophosphate enzyme, central domain K01652,K12253 - 2.2.1.6,4.1.1.75 2.196e-211 673.0
MMD2_k127_5610952_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 578.0
MMD2_k127_5610952_10 Protein of unknown function (DUF3450) - - - 0.000000000000000000000000000000000000000000000000000000000001015 219.0
MMD2_k127_5610952_11 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000001039 198.0
MMD2_k127_5610952_12 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000002601 186.0
MMD2_k127_5610952_13 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000001313 191.0
MMD2_k127_5610952_14 - - - - 0.00000000000000000000000000000000000000000000006877 178.0
MMD2_k127_5610952_15 Protein of unknown function (DUF3450) - - - 0.0000000000000000000000000000000000000000001726 167.0
MMD2_k127_5610952_16 - - - - 0.0000000000000000000000000000000000000000007562 161.0
MMD2_k127_5610952_17 SnoaL-like domain - - - 0.00000000000000000000000000000000000005945 151.0
MMD2_k127_5610952_18 - - - - 0.00000000000000000000000000000000000006323 158.0
MMD2_k127_5610952_19 peptidyl-tyrosine sulfation K13992 - - 0.000000000000000000000000000000001208 139.0
MMD2_k127_5610952_2 Major facilitator superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 509.0
MMD2_k127_5610952_20 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000003209 140.0
MMD2_k127_5610952_21 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000009313 134.0
MMD2_k127_5610952_22 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000001705 132.0
MMD2_k127_5610952_23 PepSY-associated TM region - - - 0.0000000000000000000000000000001807 135.0
MMD2_k127_5610952_24 Domain of unknown function (DUF4440) - - - 0.0000000001545 68.0
MMD2_k127_5610952_25 - - - - 0.000000000235 69.0
MMD2_k127_5610952_26 NAD ADP-ribosyltransferase activity. It is involved in the biological process described with protein ADP-ribosylation K10798 GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251 2.4.2.30 0.00000001063 63.0
MMD2_k127_5610952_3 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 486.0
MMD2_k127_5610952_4 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 419.0
MMD2_k127_5610952_5 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 408.0
MMD2_k127_5610952_6 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 396.0
MMD2_k127_5610952_7 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 297.0
MMD2_k127_5610952_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002556 283.0
MMD2_k127_5610952_9 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000003777 225.0
MMD2_k127_5616575_0 ATP-dependent helicase K03579 - 3.6.4.13 9.076e-263 837.0
MMD2_k127_5616575_1 Aspartate tyrosine aromatic aminotransferase K00813,K00832 - 2.6.1.1,2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 435.0
MMD2_k127_5616575_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 395.0
MMD2_k127_5616575_3 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 372.0
MMD2_k127_5616575_4 regulation of cobalamin metabolic process K11390 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003693 265.0
MMD2_k127_5616575_5 Bacterial virulence protein (VirJ) - - - 0.00001407 57.0
MMD2_k127_5616575_6 e3 binding domain K00658 - 2.3.1.61 0.0001697 46.0
MMD2_k127_5648_0 Belongs to the glutamate synthase family - - - 4.651e-264 827.0
MMD2_k127_5648_1 Phenazine biosynthesis protein phzf family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 460.0
MMD2_k127_5648_11 FR47-like protein - - - 0.00000000000000000006942 100.0
MMD2_k127_5648_12 - - - - 0.00000000000000133 85.0
MMD2_k127_5648_13 SlyX K03745 - - 0.0004608 48.0
MMD2_k127_5648_2 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 432.0
MMD2_k127_5648_3 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 323.0
MMD2_k127_5648_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001795 250.0
MMD2_k127_5648_5 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000005697 252.0
MMD2_k127_5648_6 Belongs to the Dps family K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000001607 208.0
MMD2_k127_5648_7 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000001118 180.0
MMD2_k127_5648_8 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000004961 157.0
MMD2_k127_5648_9 Putative phosphatase (DUF442) - - - 0.000000000000000000000000002056 118.0
MMD2_k127_5679222_0 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 494.0
MMD2_k127_5679222_1 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 455.0
MMD2_k127_5679222_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000445 196.0
MMD2_k127_5679222_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000006798 197.0
MMD2_k127_5679222_12 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000006955 146.0
MMD2_k127_5679222_13 arsR family - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000002242 132.0
MMD2_k127_5679222_14 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000001027 111.0
MMD2_k127_5679222_15 AraC-binding-like domain - - - 0.00000000000000000000000008196 121.0
MMD2_k127_5679222_16 - - - - 0.0000000003487 72.0
MMD2_k127_5679222_17 Circularly permuted ATP-grasp type 2 - - - 0.0000000006217 67.0
MMD2_k127_5679222_2 geranylgeranyl reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 381.0
MMD2_k127_5679222_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 305.0
MMD2_k127_5679222_4 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006919 302.0
MMD2_k127_5679222_5 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002073 247.0
MMD2_k127_5679222_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001191 256.0
MMD2_k127_5679222_7 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000008507 225.0
MMD2_k127_5679222_8 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000002199 215.0
MMD2_k127_5679222_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000005227 214.0
MMD2_k127_5703584_0 Amino acid adenylation domain - - - 0.0 1377.0
MMD2_k127_5703584_1 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1096.0
MMD2_k127_5703584_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000008227 236.0
MMD2_k127_5703584_11 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000118 235.0
MMD2_k127_5703584_12 Redoxin domain protein - - - 0.0000000000000000000000000000000000000000000007463 173.0
MMD2_k127_5703584_13 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000002258 169.0
MMD2_k127_5703584_14 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000009976 173.0
MMD2_k127_5703584_15 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000005376 159.0
MMD2_k127_5703584_16 - - - - 0.0000000000000000000000000000000000543 146.0
MMD2_k127_5703584_17 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000001355 139.0
MMD2_k127_5703584_18 Family of unknown function (DUF5335) - - - 0.00000000000000000000000001748 113.0
MMD2_k127_5703584_19 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000001001 108.0
MMD2_k127_5703584_2 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 552.0
MMD2_k127_5703584_21 SET domain - - - 0.0000000000000000004711 94.0
MMD2_k127_5703584_22 Isochorismatase family K09020 - 3.5.1.110 0.000000000000009236 88.0
MMD2_k127_5703584_23 Peptidase family S51 - - - 0.000000000001692 80.0
MMD2_k127_5703584_24 - - - - 0.00000007713 60.0
MMD2_k127_5703584_25 - - - - 0.0001591 47.0
MMD2_k127_5703584_3 phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 505.0
MMD2_k127_5703584_4 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 487.0
MMD2_k127_5703584_5 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 383.0
MMD2_k127_5703584_6 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 342.0
MMD2_k127_5703584_7 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 310.0
MMD2_k127_5703584_8 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001055 295.0
MMD2_k127_5703584_9 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003595 258.0
MMD2_k127_5741011_0 Carbon starvation protein K06200 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0 1094.0
MMD2_k127_5741011_1 TIGRFAM FeS assembly protein SufB K09014 - - 4.038e-271 840.0
MMD2_k127_5741011_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 477.0
MMD2_k127_5741011_11 Signal peptide peptidase K04773 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 477.0
MMD2_k127_5741011_12 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 448.0
MMD2_k127_5741011_13 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 434.0
MMD2_k127_5741011_14 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 362.0
MMD2_k127_5741011_15 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 361.0
MMD2_k127_5741011_16 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 338.0
MMD2_k127_5741011_17 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 356.0
MMD2_k127_5741011_18 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 304.0
MMD2_k127_5741011_19 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 308.0
MMD2_k127_5741011_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.936e-220 706.0
MMD2_k127_5741011_20 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001316 288.0
MMD2_k127_5741011_21 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005482 291.0
MMD2_k127_5741011_22 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000106 287.0
MMD2_k127_5741011_23 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005642 281.0
MMD2_k127_5741011_24 PFAM Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000248 279.0
MMD2_k127_5741011_25 FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003762 259.0
MMD2_k127_5741011_26 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001322 258.0
MMD2_k127_5741011_27 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006759 262.0
MMD2_k127_5741011_28 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001505 255.0
MMD2_k127_5741011_29 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000003545 241.0
MMD2_k127_5741011_3 Bacterial protein of unknown function (DUF853) K06915 - - 1.65e-208 660.0
MMD2_k127_5741011_30 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001359 232.0
MMD2_k127_5741011_32 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000004661 196.0
MMD2_k127_5741011_33 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000005815 193.0
MMD2_k127_5741011_34 - - - - 0.00000000000000000000000000000000000000000000000000001228 197.0
MMD2_k127_5741011_35 PFAM Amino acid-binding ACT K03567 - - 0.00000000000000000000000000000000000000000000000000001692 193.0
MMD2_k127_5741011_36 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000008936 185.0
MMD2_k127_5741011_37 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000003008 186.0
MMD2_k127_5741011_38 TIGRFAM SUF system FeS K04488 - - 0.0000000000000000000000000000000000000000000000009766 178.0
MMD2_k127_5741011_39 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000007353 167.0
MMD2_k127_5741011_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 567.0
MMD2_k127_5741011_40 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000005815 171.0
MMD2_k127_5741011_41 SH3 domain K07184 - - 0.00000000000000000000000000000000000001214 153.0
MMD2_k127_5741011_42 - - - - 0.0000000000000000000000000000000000002401 145.0
MMD2_k127_5741011_43 HIT family K02503 - - 0.0000000000000000000000000000000000003059 144.0
MMD2_k127_5741011_44 transcriptional regulator - - - 0.000000000000000000000000000000000001436 143.0
MMD2_k127_5741011_45 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000152 139.0
MMD2_k127_5741011_46 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000002463 141.0
MMD2_k127_5741011_47 Histidine phosphatase superfamily (branch 1) K08296 - - 0.000000000000000000000000000000000312 144.0
MMD2_k127_5741011_48 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002358 126.0
MMD2_k127_5741011_49 - - - - 0.000000000000000000000000000005415 128.0
MMD2_k127_5741011_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 561.0
MMD2_k127_5741011_50 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000000002465 123.0
MMD2_k127_5741011_51 pathogenesis - - - 0.000000000000000000000000002029 120.0
MMD2_k127_5741011_52 Protein of unknown function (DUF1249) K09920 - - 0.0000000000000000000000002627 111.0
MMD2_k127_5741011_53 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000003837 109.0
MMD2_k127_5741011_54 YceI-like domain - - - 0.000000000000000000000002271 111.0
MMD2_k127_5741011_55 histone H2A K63-linked ubiquitination K21397 - - 0.0000000000005899 82.0
MMD2_k127_5741011_56 Selenoprotein, putative - - - 0.000000000001521 71.0
MMD2_k127_5741011_57 Recombinase zinc beta ribbon domain K06400 - - 0.000000001835 61.0
MMD2_k127_5741011_58 Site-specific recombinase, DNA invertase Pin - - - 0.0000002997 55.0
MMD2_k127_5741011_59 membrane - - - 0.0000155 56.0
MMD2_k127_5741011_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 547.0
MMD2_k127_5741011_7 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 531.0
MMD2_k127_5741011_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 512.0
MMD2_k127_5741011_9 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 497.0
MMD2_k127_5932054_0 Belongs to the GcvT family K15066 - 2.1.1.341 8.315e-253 784.0
MMD2_k127_5932054_1 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 2.508e-223 701.0
MMD2_k127_5932054_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 432.0
MMD2_k127_5932054_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 413.0
MMD2_k127_5932054_12 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 341.0
MMD2_k127_5932054_13 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 320.0
MMD2_k127_5932054_14 Branched-chain-amino-acid aminotransferase-like protein 3 K18482 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008153,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0019438,GO:0019752,GO:0032787,GO:0042537,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046482,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 302.0
MMD2_k127_5932054_15 PFAM cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000009314 214.0
MMD2_k127_5932054_16 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000001661 217.0
MMD2_k127_5932054_17 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000006974 206.0
MMD2_k127_5932054_18 - - - - 0.000000000000000000000000000000000000000000000000000001104 210.0
MMD2_k127_5932054_19 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000001008 190.0
MMD2_k127_5932054_2 Belongs to the IlvD Edd family - - - 6.461e-217 688.0
MMD2_k127_5932054_20 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000002856 162.0
MMD2_k127_5932054_21 PEP-CTERM motif - - - 0.0000000000000000000000000000000003951 138.0
MMD2_k127_5932054_22 Sensor histidine kinase, Cache_1, HAMP and PAS domain-containing - - - 0.000000000000000000000000000000003339 148.0
MMD2_k127_5932054_23 Periplasmic or secreted lipoprotein K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.000000000000000000000000000000005134 137.0
MMD2_k127_5932054_24 Cytochrome c - - - 0.000000000000000000000000004384 121.0
MMD2_k127_5932054_25 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000002253 109.0
MMD2_k127_5932054_26 amidohydrolase - - - 0.00000000000000002599 83.0
MMD2_k127_5932054_27 Glycine zipper 2TM domain - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.0000000000001041 78.0
MMD2_k127_5932054_28 UPF0391 membrane protein - - - 0.000000000003232 69.0
MMD2_k127_5932054_29 aldo keto reductase - - - 0.0000000000401 68.0
MMD2_k127_5932054_3 Dehydrogenase K00117 - 1.1.5.2 9.098e-216 693.0
MMD2_k127_5932054_30 - - - - 0.000006308 52.0
MMD2_k127_5932054_31 - - - - 0.0007884 49.0
MMD2_k127_5932054_32 - - - - 0.0008 48.0
MMD2_k127_5932054_4 efflux transmembrane transporter activity - - - 4.475e-206 681.0
MMD2_k127_5932054_5 PFAM glycine cleavage T protein (aminomethyl transferase) - - - 5.194e-198 627.0
MMD2_k127_5932054_6 Transcriptional regulator - - - 1.759e-196 623.0
MMD2_k127_5932054_7 PQQ-like domain K00114 - 1.1.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 520.0
MMD2_k127_5932054_8 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 460.0
MMD2_k127_5932054_9 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 432.0
MMD2_k127_5932158_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1466.0
MMD2_k127_5932158_1 Diguanylate cyclase - - - 1.01e-196 644.0
MMD2_k127_5932158_10 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000003111 248.0
MMD2_k127_5932158_11 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003403 248.0
MMD2_k127_5932158_12 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000002132 218.0
MMD2_k127_5932158_13 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000112 213.0
MMD2_k127_5932158_14 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000738 194.0
MMD2_k127_5932158_15 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000002343 171.0
MMD2_k127_5932158_16 belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000002898 152.0
MMD2_k127_5932158_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000001481 137.0
MMD2_k127_5932158_18 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000002158 135.0
MMD2_k127_5932158_19 Methyltransferase domain - - - 0.0000000000000000000000000000000003376 144.0
MMD2_k127_5932158_2 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 635.0
MMD2_k127_5932158_20 - - - - 0.00000000000000000000000000000001423 131.0
MMD2_k127_5932158_21 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001124 94.0
MMD2_k127_5932158_22 Type IV Pilus-assembly protein W - - - 0.00000000000000000002325 104.0
MMD2_k127_5932158_23 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.000000000000000009234 88.0
MMD2_k127_5932158_24 Type II transport protein GspH K08084 - - 0.00000000000000002695 89.0
MMD2_k127_5932158_25 TIGRFAM Pilus modification type IV, PilV K02671 - - 0.0000000000000003652 88.0
MMD2_k127_5932158_26 COG4970 Tfp pilus assembly protein FimT K08084,K08085 - - 0.000000003643 66.0
MMD2_k127_5932158_27 Pilus assembly protein PilX K02673 - - 0.0001184 53.0
MMD2_k127_5932158_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0006869,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010876,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0030203,GO:0031224,GO:0031226,GO:0033036,GO:0034203,GO:0034204,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097035,GO:1901135,GO:1901137,GO:1901264,GO:1901505,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 545.0
MMD2_k127_5932158_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 435.0
MMD2_k127_5932158_5 L-2-hydroxyglutarate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 406.0
MMD2_k127_5932158_6 propanoyl-CoA C-acyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 362.0
MMD2_k127_5932158_7 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 305.0
MMD2_k127_5932158_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 329.0
MMD2_k127_5932158_9 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001437 274.0
MMD2_k127_5944004_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.258e-270 846.0
MMD2_k127_5944004_1 AAA C-terminal domain K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 440.0
MMD2_k127_5944004_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 378.0
MMD2_k127_5944004_3 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 357.0
MMD2_k127_5944004_4 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000002139 138.0
MMD2_k127_5944004_5 - - - - 0.00000000000000000000000000004809 122.0
MMD2_k127_5944004_7 AI-2E family transporter - - - 0.0000000001615 65.0
MMD2_k127_5976599_0 serine-type endopeptidase activity - GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006508,GO:0006629,GO:0006807,GO:0006915,GO:0006950,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009642,GO:0009644,GO:0009892,GO:0009987,GO:0010109,GO:0010205,GO:0012501,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0033554,GO:0034605,GO:0042548,GO:0043155,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043467,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051603,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156 - 3.209e-228 749.0
MMD2_k127_5976599_1 Protein of unknown function, DUF255 K06888 - - 5.238e-223 709.0
MMD2_k127_5976599_10 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000003174 106.0
MMD2_k127_5976599_11 Belongs to the UPF0149 family K09895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000005439 92.0
MMD2_k127_5976599_2 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 571.0
MMD2_k127_5976599_3 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 339.0
MMD2_k127_5976599_4 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003309 306.0
MMD2_k127_5976599_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006215 277.0
MMD2_k127_5976599_6 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002021 231.0
MMD2_k127_5976599_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000002661 191.0
MMD2_k127_5976599_8 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000003944 151.0
MMD2_k127_5976599_9 - - - - 0.00000000000000000000000000001693 122.0
MMD2_k127_6003959_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1116.0
MMD2_k127_6003959_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.146e-270 861.0
MMD2_k127_6003959_10 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 425.0
MMD2_k127_6003959_11 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 409.0
MMD2_k127_6003959_12 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 395.0
MMD2_k127_6003959_13 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 352.0
MMD2_k127_6003959_14 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 347.0
MMD2_k127_6003959_15 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 338.0
MMD2_k127_6003959_16 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 312.0
MMD2_k127_6003959_17 abc transporter atp-binding protein K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003326 278.0
MMD2_k127_6003959_18 COG1668 ABC-type Na efflux pump, permease component K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007233 273.0
MMD2_k127_6003959_19 nitrogen compound transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005898 274.0
MMD2_k127_6003959_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.635e-247 769.0
MMD2_k127_6003959_20 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000004904 251.0
MMD2_k127_6003959_21 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000003443 256.0
MMD2_k127_6003959_22 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000002348 237.0
MMD2_k127_6003959_23 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000006464 223.0
MMD2_k127_6003959_24 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000003306 201.0
MMD2_k127_6003959_25 cytochrome - - - 0.000000000000000000000000000000000000000000000001404 181.0
MMD2_k127_6003959_26 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000009289 152.0
MMD2_k127_6003959_27 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000005437 117.0
MMD2_k127_6003959_28 rhodanese-related sulfurtransferase K01011 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.8.1.1,2.8.1.2 0.0000000000000000000001116 102.0
MMD2_k127_6003959_29 diguanylate cyclase - - - 0.0000000000000000000001743 106.0
MMD2_k127_6003959_3 Belongs to the class-II aminoacyl-tRNA synthetase family K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 1.092e-204 649.0
MMD2_k127_6003959_30 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000004335 96.0
MMD2_k127_6003959_31 Domain of unknown function (DUF4124) - - - 0.0000000000000000006868 93.0
MMD2_k127_6003959_32 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001105 79.0
MMD2_k127_6003959_4 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 619.0
MMD2_k127_6003959_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 604.0
MMD2_k127_6003959_6 response regulator K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 560.0
MMD2_k127_6003959_7 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 572.0
MMD2_k127_6003959_8 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 488.0
MMD2_k127_6003959_9 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 450.0
MMD2_k127_6024864_0 carboxylic acid catabolic process K01684 - 4.2.1.6 9.616e-225 702.0
MMD2_k127_6024864_1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K20940 - 1.14.13.218 4.408e-215 676.0
MMD2_k127_6024864_2 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 532.0
MMD2_k127_6024864_3 Major facilitator superfamily K08195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 477.0
MMD2_k127_6024864_4 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 387.0
MMD2_k127_6024864_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 361.0
MMD2_k127_6024864_6 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 308.0
MMD2_k127_6024864_7 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000002348 209.0
MMD2_k127_6028512_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 629.0
MMD2_k127_6028512_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 468.0
MMD2_k127_6028512_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 356.0
MMD2_k127_6028512_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 293.0
MMD2_k127_6028512_4 response regulator receiver K07713,K07715 - - 0.000000000000000000000000000000000000000000001085 170.0
MMD2_k127_6028512_5 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000008844 92.0
MMD2_k127_6035747_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 4.774e-290 900.0
MMD2_k127_6035747_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 323.0
MMD2_k127_6035747_2 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007851 237.0
MMD2_k127_6035747_3 Regulatory protein, FmdB family - - - 0.00000000000000000000000001675 113.0
MMD2_k127_6036307_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.302e-220 697.0
MMD2_k127_6036307_1 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 8.846e-196 626.0
MMD2_k127_6036307_10 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 327.0
MMD2_k127_6036307_11 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000000000000000000000004426 207.0
MMD2_k127_6036307_12 transcriptional regulator K18301 - - 0.000000000000000008576 95.0
MMD2_k127_6036307_13 Bacterial regulatory proteins, tetR family - - - 0.000000006555 66.0
MMD2_k127_6036307_2 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 554.0
MMD2_k127_6036307_3 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 492.0
MMD2_k127_6036307_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 439.0
MMD2_k127_6036307_5 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 417.0
MMD2_k127_6036307_6 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 402.0
MMD2_k127_6036307_7 S-adenosylmethionine-dependent methyltransferase K06969,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.191,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 396.0
MMD2_k127_6036307_8 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 374.0
MMD2_k127_6036307_9 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 325.0
MMD2_k127_6049279_0 Multicopper oxidase - - - 2.315e-239 752.0
MMD2_k127_6049279_1 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 401.0
MMD2_k127_6049279_2 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 356.0
MMD2_k127_6049279_3 copper resistance K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 268.0
MMD2_k127_6049279_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000002727 126.0
MMD2_k127_6056593_0 Oxaloacetate decarboxylase K01571 - 4.1.1.3 1.372e-254 798.0
MMD2_k127_6056593_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.636e-249 779.0
MMD2_k127_6056593_10 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 479.0
MMD2_k127_6056593_11 ATPase with chaperone activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 473.0
MMD2_k127_6056593_12 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 479.0
MMD2_k127_6056593_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 439.0
MMD2_k127_6056593_14 FAD linked oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 440.0
MMD2_k127_6056593_15 Retinal pigment epithelial membrane protein K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 412.0
MMD2_k127_6056593_16 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 381.0
MMD2_k127_6056593_17 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 372.0
MMD2_k127_6056593_18 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 373.0
MMD2_k127_6056593_19 Flp pilus assembly protein TadB K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 332.0
MMD2_k127_6056593_2 COG4993 Glucose dehydrogenase - - - 1.542e-205 671.0
MMD2_k127_6056593_20 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 339.0
MMD2_k127_6056593_21 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 326.0
MMD2_k127_6056593_22 Glutathione S-transferase, N-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 317.0
MMD2_k127_6056593_23 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 313.0
MMD2_k127_6056593_25 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001041 288.0
MMD2_k127_6056593_26 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003957 272.0
MMD2_k127_6056593_27 Cellulose biosynthesis protein BcsQ K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 276.0
MMD2_k127_6056593_28 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000005297 233.0
MMD2_k127_6056593_29 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000116 213.0
MMD2_k127_6056593_3 DNA topological change K03168 - 5.99.1.2 2.321e-194 633.0
MMD2_k127_6056593_30 ankyrin repeat K15503 - - 0.0000000000000000000000000000000000000000000000000000000004143 220.0
MMD2_k127_6056593_31 regulator - - - 0.000000000000000000000000000000000000000000000000007509 190.0
MMD2_k127_6056593_32 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000001616 184.0
MMD2_k127_6056593_33 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000006575 189.0
MMD2_k127_6056593_34 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000007621 179.0
MMD2_k127_6056593_35 TadE-like protein - - - 0.0000000000000000000000000000000000001908 145.0
MMD2_k127_6056593_36 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000009786 145.0
MMD2_k127_6056593_37 TadE-like protein - - - 0.00000000000000000000000000003917 125.0
MMD2_k127_6056593_38 Cupredoxin-like domain K02275 - 1.9.3.1 0.0000000000000000000000000001026 126.0
MMD2_k127_6056593_39 SnoaL-like domain - - - 0.0000000000000000000000000007924 128.0
MMD2_k127_6056593_4 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 603.0
MMD2_k127_6056593_40 Carboxylesterase family - - - 0.00000000000000000000000009925 125.0
MMD2_k127_6056593_41 - - - - 0.0000000000000000000000001447 112.0
MMD2_k127_6056593_42 - - - - 0.00000000000000000000007383 113.0
MMD2_k127_6056593_43 aspartic-type endopeptidase activity K02278,K02654 - 3.4.23.43 0.00000000000000005724 89.0
MMD2_k127_6056593_45 SnoaL-like domain - - - 0.00000000000004269 85.0
MMD2_k127_6056593_46 - K02651 - - 0.000000007952 59.0
MMD2_k127_6056593_47 - - - - 0.0000068 53.0
MMD2_k127_6056593_48 Metallo-beta-lactamase superfamily - - - 0.000009489 59.0
MMD2_k127_6056593_49 Lyase and sodium transporter K01573 - 4.1.1.3 0.0002844 47.0
MMD2_k127_6056593_5 pilus assembly protein, ATPase CpaF K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 591.0
MMD2_k127_6056593_6 decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 535.0
MMD2_k127_6056593_7 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 497.0
MMD2_k127_6056593_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 503.0
MMD2_k127_6056593_9 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 498.0
MMD2_k127_612370_0 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 613.0
MMD2_k127_612370_1 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 614.0
MMD2_k127_612370_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000005665 237.0
MMD2_k127_612370_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001549 226.0
MMD2_k127_612370_12 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000003233 216.0
MMD2_k127_612370_13 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002387 203.0
MMD2_k127_612370_14 Maf-like protein K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.000000000000000000000000000000000000000000000000000005693 196.0
MMD2_k127_612370_15 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.00000000000000000000000000000000000000000000000000007212 198.0
MMD2_k127_612370_2 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 454.0
MMD2_k127_612370_3 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 399.0
MMD2_k127_612370_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 375.0
MMD2_k127_612370_5 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 400.0
MMD2_k127_612370_6 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 339.0
MMD2_k127_612370_7 Type II secretory pathway component ExeA K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 328.0
MMD2_k127_612370_8 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002467 288.0
MMD2_k127_612370_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005678 275.0
MMD2_k127_6166009_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 578.0
MMD2_k127_6166009_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 407.0
MMD2_k127_6166009_2 AraC-binding-like domain - - - 0.00000000000000000000000000001348 130.0
MMD2_k127_6166009_3 - - - - 0.00000000000000000338 100.0
MMD2_k127_6210730_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 2.261e-227 717.0
MMD2_k127_6210730_1 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 500.0
MMD2_k127_6210730_2 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001068 222.0
MMD2_k127_6210730_3 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000001409 215.0
MMD2_k127_6210730_4 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000005343 183.0
MMD2_k127_6210730_5 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000008435 143.0
MMD2_k127_6210730_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000002215 118.0
MMD2_k127_6210730_7 YjbR - - - 0.000000000000000000000002946 106.0
MMD2_k127_6210730_8 Protein of unknown function (DUF2934) - - - 0.000002943 53.0
MMD2_k127_6210730_9 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0003014 47.0
MMD2_k127_6231575_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 451.0
MMD2_k127_6231575_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 325.0
MMD2_k127_6231575_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000003231 247.0
MMD2_k127_6231575_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000008721 205.0
MMD2_k127_6231575_4 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000006816 177.0
MMD2_k127_6231575_5 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000002079 144.0
MMD2_k127_6231575_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000001274 134.0
MMD2_k127_6231575_7 Putative prokaryotic signal transducing protein - - - 0.0000000000000002741 91.0
MMD2_k127_625840_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 1.536e-257 822.0
MMD2_k127_625840_1 ABC transporter K06147,K06148 - - 1.647e-247 779.0
MMD2_k127_625840_10 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000003602 207.0
MMD2_k127_625840_11 Putative zinc- or iron-chelating domain K09160 - - 0.0000000000000000000000000000000000000000000000000000006288 198.0
MMD2_k127_625840_12 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000004871 180.0
MMD2_k127_625840_13 Anthranilate phosphoribosyltransferase K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0031967,GO:0031975,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000005922 77.0
MMD2_k127_625840_2 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 8.598e-207 659.0
MMD2_k127_625840_3 dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 422.0
MMD2_k127_625840_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 407.0
MMD2_k127_625840_5 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 314.0
MMD2_k127_625840_6 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003264 298.0
MMD2_k127_625840_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004012 278.0
MMD2_k127_625840_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000007807 245.0
MMD2_k127_625840_9 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000002561 246.0
MMD2_k127_6260344_0 2 iron, 2 sulfur cluster binding - - - 0.0 1656.0
MMD2_k127_6260344_1 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1364.0
MMD2_k127_6260344_10 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 493.0
MMD2_k127_6260344_11 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 495.0
MMD2_k127_6260344_12 Trypsin K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 471.0
MMD2_k127_6260344_13 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 480.0
MMD2_k127_6260344_14 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 458.0
MMD2_k127_6260344_15 MCM2/3/5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 440.0
MMD2_k127_6260344_16 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 456.0
MMD2_k127_6260344_17 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 411.0
MMD2_k127_6260344_18 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 423.0
MMD2_k127_6260344_19 collagen metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 412.0
MMD2_k127_6260344_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1362.0
MMD2_k127_6260344_20 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 370.0
MMD2_k127_6260344_21 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 342.0
MMD2_k127_6260344_22 Putative vitamin uptake transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 334.0
MMD2_k127_6260344_23 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 344.0
MMD2_k127_6260344_24 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 347.0
MMD2_k127_6260344_25 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 337.0
MMD2_k127_6260344_26 Aminotransferase, class I K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 334.0
MMD2_k127_6260344_27 Pyrogallol hydroxytransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 328.0
MMD2_k127_6260344_28 PFAM peptidase K04774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 329.0
MMD2_k127_6260344_29 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 325.0
MMD2_k127_6260344_3 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - 0.0 1113.0
MMD2_k127_6260344_30 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 316.0
MMD2_k127_6260344_31 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 301.0
MMD2_k127_6260344_32 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 302.0
MMD2_k127_6260344_33 PFAM ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 309.0
MMD2_k127_6260344_34 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 290.0
MMD2_k127_6260344_35 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 286.0
MMD2_k127_6260344_36 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007527 274.0
MMD2_k127_6260344_37 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001108 279.0
MMD2_k127_6260344_38 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000346 265.0
MMD2_k127_6260344_39 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000005721 271.0
MMD2_k127_6260344_4 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.213e-243 777.0
MMD2_k127_6260344_40 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002975 263.0
MMD2_k127_6260344_41 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004204 268.0
MMD2_k127_6260344_42 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001851 252.0
MMD2_k127_6260344_43 Haloacid dehalogenase-like hydrolase K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000001055 244.0
MMD2_k127_6260344_44 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000002739 246.0
MMD2_k127_6260344_45 Glyoxalase bleomycin resistance protein dioxygenase K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000496 235.0
MMD2_k127_6260344_46 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000008327 236.0
MMD2_k127_6260344_47 - - - - 0.000000000000000000000000000000000000000000000000000000000000001511 230.0
MMD2_k127_6260344_48 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000000000000000000000000000000000000000000000000000000003465 229.0
MMD2_k127_6260344_49 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000005587 222.0
MMD2_k127_6260344_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.362e-228 715.0
MMD2_k127_6260344_50 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000001325 241.0
MMD2_k127_6260344_51 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001761 227.0
MMD2_k127_6260344_52 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000003201 226.0
MMD2_k127_6260344_53 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000003284 225.0
MMD2_k127_6260344_54 6-pyruvoyl tetrahydropterin synthase - - - 0.00000000000000000000000000000000000000000000000000000000006721 207.0
MMD2_k127_6260344_55 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000127 200.0
MMD2_k127_6260344_56 PFAM phosphoesterase PA-phosphatase related K09474 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.1.3.2 0.000000000000000000000000000000000000000000000000000004649 203.0
MMD2_k127_6260344_57 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000005038 193.0
MMD2_k127_6260344_58 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000005125 196.0
MMD2_k127_6260344_59 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000008135 195.0
MMD2_k127_6260344_6 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 1.496e-207 698.0
MMD2_k127_6260344_60 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002152 186.0
MMD2_k127_6260344_61 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000004248 177.0
MMD2_k127_6260344_62 peptidase - - - 0.00000000000000000000000000000000000000000000004739 180.0
MMD2_k127_6260344_63 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000001273 172.0
MMD2_k127_6260344_64 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000003025 172.0
MMD2_k127_6260344_65 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000002519 160.0
MMD2_k127_6260344_66 LemA family K03744 - - 0.00000000000000000000000000000404 128.0
MMD2_k127_6260344_67 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000001211 108.0
MMD2_k127_6260344_68 Domain of unknown function (DUF4381) - - - 0.000000000000000000000003804 111.0
MMD2_k127_6260344_69 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000000000000000000000004862 117.0
MMD2_k127_6260344_7 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04099 - 1.13.11.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 559.0
MMD2_k127_6260344_70 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000000000000000005633 107.0
MMD2_k127_6260344_71 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.0000000000000000000008291 102.0
MMD2_k127_6260344_72 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000008612 110.0
MMD2_k127_6260344_73 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000001341 101.0
MMD2_k127_6260344_74 - - - - 0.00000000000004407 78.0
MMD2_k127_6260344_75 small protein containing a coiled-coil domain - - - 0.0000000000001476 73.0
MMD2_k127_6260344_76 YCII-related domain - - - 0.0000000000001618 79.0
MMD2_k127_6260344_79 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.000000000001191 69.0
MMD2_k127_6260344_8 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 559.0
MMD2_k127_6260344_80 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000003735 78.0
MMD2_k127_6260344_81 Putative diguanylate phosphodiesterase - - - 0.00000000008097 65.0
MMD2_k127_6260344_82 - - - - 0.000000001518 66.0
MMD2_k127_6260344_83 RNA-binding - - - 0.000000002913 62.0
MMD2_k127_6260344_84 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.00000001742 63.0
MMD2_k127_6260344_86 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.000003229 59.0
MMD2_k127_6260344_87 - - - - 0.00001096 50.0
MMD2_k127_6260344_88 PFAM Glucose Sorbosone dehydrogenase K21430 - - 0.0004812 53.0
MMD2_k127_6260344_9 Aldehyde dehydrogenase family K13922,K18119 - 1.2.1.76,1.2.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 525.0
MMD2_k127_673513_0 receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001159 276.0
MMD2_k127_673513_1 COG3202 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000009678 244.0
MMD2_k127_673513_2 SnoaL-like domain - - - 0.000000000000000000000000007104 121.0
MMD2_k127_673513_3 SnoaL-like domain - - - 0.0000000000000001587 93.0
MMD2_k127_803700_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1145.0
MMD2_k127_803700_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 2.51e-233 734.0
MMD2_k127_803700_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 393.0
MMD2_k127_803700_11 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 371.0
MMD2_k127_803700_12 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 382.0
MMD2_k127_803700_13 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02464,K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 329.0
MMD2_k127_803700_14 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002692 284.0
MMD2_k127_803700_15 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000001063 258.0
MMD2_k127_803700_16 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000002132 218.0
MMD2_k127_803700_17 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000008056 206.0
MMD2_k127_803700_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000002155 205.0
MMD2_k127_803700_19 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000003564 189.0
MMD2_k127_803700_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.47e-203 638.0
MMD2_k127_803700_20 Pilin (bacterial filament) K02650,K02655 - - 0.000000000000000000000000000000000000000000002184 169.0
MMD2_k127_803700_21 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000000000000000000000000005185 159.0
MMD2_k127_803700_22 belongs to the nudix hydrolase family K03574 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.000000000000000000000000000006389 128.0
MMD2_k127_803700_23 Pilin (bacterial filament) K02650,K02655 - - 0.00000000000000001312 93.0
MMD2_k127_803700_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 622.0
MMD2_k127_803700_4 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 548.0
MMD2_k127_803700_5 response regulator receiver K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 540.0
MMD2_k127_803700_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 512.0
MMD2_k127_803700_7 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 501.0
MMD2_k127_803700_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 495.0
MMD2_k127_803700_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 445.0
MMD2_k127_823457_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 361.0
MMD2_k127_823457_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 351.0
MMD2_k127_823457_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 294.0
MMD2_k127_823457_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000497 260.0
MMD2_k127_823457_4 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000000000000000000000000000001095 227.0
MMD2_k127_823457_5 3-carboxyethylcatechol 2,3-dioxygenase activity K04100 - 1.13.11.8 0.000000000000000000000002836 106.0
MMD2_k127_823457_7 Sh3 type 3 domain protein - - - 0.00000000004156 71.0
MMD2_k127_851183_0 Dehydrogenase E1 component K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 0.0 1094.0
MMD2_k127_851183_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 7.899e-270 855.0
MMD2_k127_851183_10 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 429.0
MMD2_k127_851183_11 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 429.0
MMD2_k127_851183_12 PFAM Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 380.0
MMD2_k127_851183_13 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 377.0
MMD2_k127_851183_14 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 360.0
MMD2_k127_851183_15 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 361.0
MMD2_k127_851183_16 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 328.0
MMD2_k127_851183_17 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 331.0
MMD2_k127_851183_18 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 323.0
MMD2_k127_851183_19 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 305.0
MMD2_k127_851183_2 Major Facilitator Superfamily - - - 2.297e-262 818.0
MMD2_k127_851183_20 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 315.0
MMD2_k127_851183_21 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004444 254.0
MMD2_k127_851183_22 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001821 250.0
MMD2_k127_851183_23 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000002696 252.0
MMD2_k127_851183_24 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000001055 218.0
MMD2_k127_851183_25 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000004014 210.0
MMD2_k127_851183_26 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000002502 191.0
MMD2_k127_851183_27 Poly-gamma-glutamate hydrolase - - - 0.0000000000000000000000000000000000000000000000003281 183.0
MMD2_k127_851183_28 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.00000000000000000000000000000000000000000000000421 180.0
MMD2_k127_851183_29 Protein of unknown function (DUF3187) - - - 0.00000000000000000000000000000000000000000000002207 183.0
MMD2_k127_851183_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.126e-224 714.0
MMD2_k127_851183_30 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000001437 171.0
MMD2_k127_851183_31 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000004213 166.0
MMD2_k127_851183_32 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000004617 164.0
MMD2_k127_851183_33 transcriptional regulator - - - 0.0000000000000000000000000000000000000002981 157.0
MMD2_k127_851183_34 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000002215 156.0
MMD2_k127_851183_35 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000000000000000000169 166.0
MMD2_k127_851183_36 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000002697 149.0
MMD2_k127_851183_37 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000001211 150.0
MMD2_k127_851183_38 universal stress protein K14055 - - 0.0000000000000000000000000000000000004298 152.0
MMD2_k127_851183_39 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000004621 128.0
MMD2_k127_851183_4 Aldehyde dehydrogenase family K21802 - 1.2.1.67 8.066e-195 624.0
MMD2_k127_851183_40 Thioesterase K01075,K07107 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790 3.1.2.23 0.0000000000000000000000000000002315 127.0
MMD2_k127_851183_41 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000000422 129.0
MMD2_k127_851183_42 COG3474 Cytochrome c2 K08738 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000000008079 121.0
MMD2_k127_851183_43 COG0666 FOG Ankyrin repeat K06867 - - 0.000000000000000000000000009518 126.0
MMD2_k127_851183_44 CBS domain - - - 0.0000000000000000000009446 102.0
MMD2_k127_851183_45 TonB C terminal K03646 - - 0.00000000000001727 83.0
MMD2_k127_851183_46 - - - - 0.000000000329 68.0
MMD2_k127_851183_5 DNA topological change K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 610.0
MMD2_k127_851183_6 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 571.0
MMD2_k127_851183_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 522.0
MMD2_k127_851183_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 482.0
MMD2_k127_851183_9 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 451.0
MMD2_k127_869497_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 592.0
MMD2_k127_869497_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 577.0
MMD2_k127_869497_10 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000001197 182.0
MMD2_k127_869497_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000004596 80.0
MMD2_k127_869497_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 430.0
MMD2_k127_869497_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 415.0
MMD2_k127_869497_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 392.0
MMD2_k127_869497_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 393.0
MMD2_k127_869497_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 362.0
MMD2_k127_869497_7 Peptidoglycan polymerase that is essential for cell division K03588 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 344.0
MMD2_k127_869497_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 329.0
MMD2_k127_869497_9 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000000006345 206.0
MMD2_k127_870239_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 1.738e-264 834.0
MMD2_k127_870239_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.693e-218 692.0
MMD2_k127_870239_10 nicotinamide mononucleotide transporter K03811 - - 0.0000000000000000000000000000000000000000000000000000002191 201.0
MMD2_k127_870239_11 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000007177 191.0
MMD2_k127_870239_12 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000000004908 170.0
MMD2_k127_870239_13 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000001069 115.0
MMD2_k127_870239_14 Choline kinase - - - 0.00000000000005748 85.0
MMD2_k127_870239_2 TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 569.0
MMD2_k127_870239_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 452.0
MMD2_k127_870239_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 409.0
MMD2_k127_870239_5 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 408.0
MMD2_k127_870239_6 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 363.0
MMD2_k127_870239_7 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 334.0
MMD2_k127_870239_8 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 321.0
MMD2_k127_870239_9 Tryptophan 2,3-dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 305.0
MMD2_k127_876015_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 1.191e-232 752.0
MMD2_k127_876015_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000003957 211.0
MMD2_k127_876015_2 Universal stress protein family K14055 - - 0.00000000000000000000000000000000000000000000000000006692 198.0
MMD2_k127_876015_3 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000007752 160.0
MMD2_k127_876015_4 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000004224 146.0
MMD2_k127_876015_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000134 138.0
MMD2_k127_876015_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000833 134.0
MMD2_k127_876015_7 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000376 96.0
MMD2_k127_876015_8 PFAM zinc finger DksA TraR C4-type - - - 0.0000000000000002981 88.0
MMD2_k127_876015_9 PFAM Glucose Sorbosone dehydrogenase K00117,K21430 - 1.1.5.2 0.00004754 45.0
MMD2_k127_885080_0 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 563.0
MMD2_k127_885080_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 520.0
MMD2_k127_885080_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000001662 192.0
MMD2_k127_885080_3 - - - - 0.00000000000000000000000005906 123.0
MMD2_k127_885080_4 Nickel/cobalt transporter regulator - - - 0.000000000000000007636 90.0
MMD2_k127_885080_5 PFAM SMP-30 Gluconolaconase - - - 0.00005606 56.0
MMD2_k127_885080_6 - - - - 0.0001006 53.0
MMD2_k127_895170_0 Belongs to the glycosyl hydrolase 3 family - - - 6.534e-315 978.0
MMD2_k127_895170_1 SbmA/BacA-like family - - - 3.191e-217 691.0
MMD2_k127_895170_10 Methyl-transferase K06983 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 371.0
MMD2_k127_895170_11 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 377.0
MMD2_k127_895170_12 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 302.0
MMD2_k127_895170_13 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002057 282.0
MMD2_k127_895170_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001602 255.0
MMD2_k127_895170_15 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000004487 221.0
MMD2_k127_895170_16 - - - - 0.000000000000000002592 100.0
MMD2_k127_895170_17 Metallo-beta-lactamase superfamily - - - 0.0000001931 64.0
MMD2_k127_895170_2 Putative glucoamylase - - - 5.068e-216 679.0
MMD2_k127_895170_3 ABC-type oligopeptide transport system, periplasmic component K02035,K13893 - - 4.042e-207 666.0
MMD2_k127_895170_4 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 497.0
MMD2_k127_895170_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 514.0
MMD2_k127_895170_6 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 449.0
MMD2_k127_895170_7 ankyrin repeat K15503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 416.0
MMD2_k127_895170_8 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 407.0
MMD2_k127_895170_9 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 386.0
MMD2_k127_898621_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 7.147e-294 911.0
MMD2_k127_898621_1 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 597.0
MMD2_k127_898621_10 glycosyl transferase family - - - 0.000000000000000000000000000000002261 143.0
MMD2_k127_898621_11 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000001376 79.0
MMD2_k127_898621_12 rRNA processing K21402 - - 0.000000000000001814 86.0
MMD2_k127_898621_13 Sulfotransferase domain - - - 0.0000000000001918 83.0
MMD2_k127_898621_14 Protein of unknown function (DUF3018) - - - 0.000000001543 61.0
MMD2_k127_898621_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 540.0
MMD2_k127_898621_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 525.0
MMD2_k127_898621_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 405.0
MMD2_k127_898621_5 Hexosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 413.0
MMD2_k127_898621_6 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 352.0
MMD2_k127_898621_7 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 322.0
MMD2_k127_898621_8 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 312.0
MMD2_k127_898621_9 Serine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001565 248.0
MMD2_k127_908665_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1282.0
MMD2_k127_908665_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.258e-318 998.0
MMD2_k127_908665_10 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 407.0
MMD2_k127_908665_11 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 391.0
MMD2_k127_908665_12 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 365.0
MMD2_k127_908665_13 Aspartyl asparaginyl beta-hydroxylase and related dioxygenases K12979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 364.0
MMD2_k127_908665_14 (ABC) transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 342.0
MMD2_k127_908665_15 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 342.0
MMD2_k127_908665_16 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 316.0
MMD2_k127_908665_17 signal transduction histidine kinase K07644,K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 311.0
MMD2_k127_908665_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 298.0
MMD2_k127_908665_19 Protein of unknown function, DUF484 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000107 288.0
MMD2_k127_908665_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 6.824e-287 894.0
MMD2_k127_908665_20 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 258.0
MMD2_k127_908665_21 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 259.0
MMD2_k127_908665_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000001057 257.0
MMD2_k127_908665_23 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003195 235.0
MMD2_k127_908665_24 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.000000000000000000000000000000000000000000000000000000002275 206.0
MMD2_k127_908665_25 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000003981 213.0
MMD2_k127_908665_26 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000001601 203.0
MMD2_k127_908665_27 Peptidase C13 family - - - 0.000000000000000000000000000000000000000000000000001168 205.0
MMD2_k127_908665_28 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000001363 172.0
MMD2_k127_908665_29 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000005048 153.0
MMD2_k127_908665_3 FtsX-like permease family K02004 - - 6.459e-283 890.0
MMD2_k127_908665_30 transporter component K07112 - - 0.0000000000000000000000000000000000002909 145.0
MMD2_k127_908665_31 transporter component K07112 - - 0.000000000000000000000000000000000002372 151.0
MMD2_k127_908665_32 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000002655 130.0
MMD2_k127_908665_33 rhamnose metabolic process - - - 0.0000000000000000000000000005915 117.0
MMD2_k127_908665_34 PFAM Ankyrin repeat K06867 - - 0.0000000000000000000000000007533 130.0
MMD2_k127_908665_35 Outer membrane protein beta-barrel domain - - - 0.0000000000000001787 87.0
MMD2_k127_908665_36 - K01992 - - 0.00000000000001501 83.0
MMD2_k127_908665_37 efflux transmembrane transporter activity K15725 - - 0.00000001115 69.0
MMD2_k127_908665_38 Psort location Cytoplasmic, score 8.96 - - - 0.000004589 57.0
MMD2_k127_908665_39 Ring hydroxylating beta subunit - - - 0.0003264 50.0
MMD2_k127_908665_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.151e-243 764.0
MMD2_k127_908665_5 Aminotransferase class I and II K14261 - - 1.124e-232 724.0
MMD2_k127_908665_6 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 2.417e-230 726.0
MMD2_k127_908665_7 DNA topological change K03168 - 5.99.1.2 1.891e-206 672.0
MMD2_k127_908665_8 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 564.0
MMD2_k127_908665_9 HlyD family secretion protein K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 421.0
MMD2_k127_93629_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 3.723e-222 711.0
MMD2_k127_93629_1 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001458 279.0
MMD2_k127_93629_2 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009742 271.0
MMD2_k127_93629_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 275.0
MMD2_k127_93629_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002822 263.0
MMD2_k127_93629_5 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000001987 226.0
MMD2_k127_93629_6 - - - - 0.00000000000000000004977 94.0
MMD2_k127_93629_7 EF-hand domain pair - - - 0.0000000007689 66.0
MMD2_k127_93629_8 photosynthesis K12132,K20543 - 2.7.11.1 0.0005511 53.0
MMD2_k127_964054_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1086.0
MMD2_k127_964054_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.163e-198 627.0
MMD2_k127_964054_10 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 415.0
MMD2_k127_964054_11 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 410.0
MMD2_k127_964054_12 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 396.0
MMD2_k127_964054_13 periplasmic binding protein LacI transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 351.0
MMD2_k127_964054_14 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 318.0
MMD2_k127_964054_15 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 331.0
MMD2_k127_964054_16 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
MMD2_k127_964054_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 289.0
MMD2_k127_964054_18 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008236 271.0
MMD2_k127_964054_19 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000004563 270.0
MMD2_k127_964054_2 'PFAM Alpha amylase, catalytic K00690 GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006066,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0019400,GO:0019751,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0051472,GO:0071704,GO:1901615 2.4.1.7 4.224e-198 628.0
MMD2_k127_964054_20 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004727 251.0
MMD2_k127_964054_21 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000006287 243.0
MMD2_k127_964054_22 Ribosomal protein L16p/L10e K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001278 236.0
MMD2_k127_964054_23 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000007452 227.0
MMD2_k127_964054_24 Bacterial regulatory helix-turn-helix protein, lysR family K14657 - - 0.000000000000000000000000000000000000000000000000000000000000002624 232.0
MMD2_k127_964054_25 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000002826 213.0
MMD2_k127_964054_26 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000275 209.0
MMD2_k127_964054_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000000001405 207.0
MMD2_k127_964054_28 PFAM PfkB K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000004477 203.0
MMD2_k127_964054_29 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000007769 184.0
MMD2_k127_964054_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K21105 - 3.1.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 584.0
MMD2_k127_964054_30 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000002905 181.0
MMD2_k127_964054_32 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000002964 177.0
MMD2_k127_964054_33 PHP domain protein - - - 0.00000000000000000000000000000000000000000000002747 189.0
MMD2_k127_964054_34 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000006363 173.0
MMD2_k127_964054_35 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000003224 177.0
MMD2_k127_964054_36 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000003854 162.0
MMD2_k127_964054_37 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000005076 156.0
MMD2_k127_964054_38 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000002455 156.0
MMD2_k127_964054_39 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000009032 153.0
MMD2_k127_964054_40 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000009459 147.0
MMD2_k127_964054_41 Carboxylesterase family - - - 0.0000000000000000000000000000000000000216 165.0
MMD2_k127_964054_42 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000005728 132.0
MMD2_k127_964054_43 methyltransferase activity - - - 0.0000000000000000000000000000761 124.0
MMD2_k127_964054_44 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000003233 116.0
MMD2_k127_964054_45 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000001838 124.0
MMD2_k127_964054_46 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000003655 113.0
MMD2_k127_964054_47 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000003174 106.0
MMD2_k127_964054_48 transcriptional regulator - - - 0.0000000000000000000007485 104.0
MMD2_k127_964054_49 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000007915 85.0
MMD2_k127_964054_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 465.0
MMD2_k127_964054_50 Ribosomal protein L30 K02907 - - 0.00000000000000002828 84.0
MMD2_k127_964054_51 translation elongation factor activity K02358 - - 0.00000000000000004178 80.0
MMD2_k127_964054_52 - - - - 0.00000000000000004722 93.0
MMD2_k127_964054_53 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000001623 79.0
MMD2_k127_964054_54 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000472 69.0
MMD2_k127_964054_55 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000001207 69.0
MMD2_k127_964054_57 - - - - 0.0000001474 61.0
MMD2_k127_964054_58 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000005358 58.0
MMD2_k127_964054_6 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 443.0
MMD2_k127_964054_60 serine threonine protein kinase - - - 0.0003327 52.0
MMD2_k127_964054_7 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 437.0
MMD2_k127_964054_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 423.0
MMD2_k127_998704_0 PFAM Amidohydrolase 3 - - - 2.858e-196 624.0
MMD2_k127_998704_1 alginic acid biosynthetic process K01729 - 4.2.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 611.0
MMD2_k127_998704_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002464 147.0
MMD2_k127_998704_11 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000001483 116.0
MMD2_k127_998704_12 SNARE associated Golgi protein - - - 0.0000000000000000000000000574 115.0
MMD2_k127_998704_13 Psort location CytoplasmicMembrane, score - - - 0.0000001009 62.0
MMD2_k127_998704_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 595.0
MMD2_k127_998704_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 547.0
MMD2_k127_998704_4 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 545.0
MMD2_k127_998704_5 Amino acid permease K11735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 524.0
MMD2_k127_998704_6 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 413.0
MMD2_k127_998704_7 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 391.0
MMD2_k127_998704_8 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000335 283.0
MMD2_k127_998704_9 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000002017 195.0