Overview

ID MAG02684
Name MMS1_bin.74
Sample SMP0064
Taxonomy
Kingdom Archaea
Phylum Micrarchaeota
Class Micrarchaeia
Order Micrarchaeales
Family CABMGC01
Genus JAKAUU01
Species
Assembly information
Completeness (%) 89.08
Contamination (%) 1.98
GC content (%) 44.0
N50 (bp) 49,220
Genome size (bp) 890,682

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes649

Gene name Description KEGG GOs EC E-value Score Sequence
MMS1_k127_1003738_0 PD-(D/E)XK nuclease superfamily K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000671 239.0
MMS1_k127_1003738_1 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000009991 183.0
MMS1_k127_1003738_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000002108 118.0
MMS1_k127_1003738_3 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000002972 102.0
MMS1_k127_1003738_4 ERCC4 domain K10896 - - 0.0000000000000001314 82.0
MMS1_k127_1003738_5 Integrase - - - 0.0000002905 63.0
MMS1_k127_1071524_0 Voltage gated chloride channel K03281 - - 3.016e-196 628.0
MMS1_k127_1071524_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 519.0
MMS1_k127_1071524_10 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 300.0
MMS1_k127_1071524_11 COG0025 NhaP-type Na H and K H antiporters K11105 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 297.0
MMS1_k127_1071524_12 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 293.0
MMS1_k127_1071524_13 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 274.0
MMS1_k127_1071524_14 COG0656 Aldo keto reductases, related to diketogulonate reductase K06222 - 1.1.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000001365 272.0
MMS1_k127_1071524_15 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007781 268.0
MMS1_k127_1071524_16 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000002037 242.0
MMS1_k127_1071524_17 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000000000000000000000000001447 214.0
MMS1_k127_1071524_18 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000003378 219.0
MMS1_k127_1071524_19 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001168 222.0
MMS1_k127_1071524_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 495.0
MMS1_k127_1071524_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001987 208.0
MMS1_k127_1071524_21 Belongs to the complex I 20 kDa subunit family K00331,K22159 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000003146 187.0
MMS1_k127_1071524_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000001462 192.0
MMS1_k127_1071524_23 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000004036 185.0
MMS1_k127_1071524_24 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000001847 188.0
MMS1_k127_1071524_25 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000003353 171.0
MMS1_k127_1071524_26 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000005301 171.0
MMS1_k127_1071524_27 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000000124 171.0
MMS1_k127_1071524_28 PFAM Methyltransferase - - - 0.000000000000000000000000000000000000000000002828 173.0
MMS1_k127_1071524_29 Forms part of the polypeptide exit tunnel K02930 - - 0.000000000000000000000000000000000000000008681 164.0
MMS1_k127_1071524_3 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 491.0
MMS1_k127_1071524_30 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000661 168.0
MMS1_k127_1071524_31 COG1226 Kef-type K transport systems K10716 - - 0.000000000000000000000000000000000000001507 157.0
MMS1_k127_1071524_32 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000254 151.0
MMS1_k127_1071524_33 YHYH protein - - - 0.000000000000000000000000000000000007382 147.0
MMS1_k127_1071524_34 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000006924 133.0
MMS1_k127_1071524_35 Domain of unknown function (DU1801) K00784 - 3.1.26.11 0.00000000000000000000000000000008238 128.0
MMS1_k127_1071524_36 NUDIX domain - - - 0.000000000000000000000000000001057 125.0
MMS1_k127_1071524_37 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.000000000000000000000000000001307 124.0
MMS1_k127_1071524_38 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000005433 123.0
MMS1_k127_1071524_39 Belongs to the SUI1 family K03113 - - 0.000000000000000000000001668 108.0
MMS1_k127_1071524_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 440.0
MMS1_k127_1071524_40 Secreted repeat of unknown function - - - 0.000000000000000000001787 102.0
MMS1_k127_1071524_41 Amidohydrolase K07045 - - 0.0000000000000000001268 98.0
MMS1_k127_1071524_42 IPT/TIG domain - - - 0.00000000000000001272 95.0
MMS1_k127_1071524_43 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000004696 91.0
MMS1_k127_1071524_44 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000342 86.0
MMS1_k127_1071524_45 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000003647 83.0
MMS1_k127_1071524_46 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002274 79.0
MMS1_k127_1071524_47 - - - - 0.00000000000001481 74.0
MMS1_k127_1071524_48 - - - - 0.0000000000002328 72.0
MMS1_k127_1071524_49 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332,K05581,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0050136,GO:0055114,GO:0071944 1.6.5.3 0.000000001801 63.0
MMS1_k127_1071524_5 helicase superfamily c-terminal domain K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 351.0
MMS1_k127_1071524_50 Protein of unknown function (DUF3494) - - - 0.000000454 63.0
MMS1_k127_1071524_51 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000004376 55.0
MMS1_k127_1071524_52 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.000007525 49.0
MMS1_k127_1071524_53 - - - - 0.000008491 57.0
MMS1_k127_1071524_54 Ribosomal protein S26e K02976 - - 0.00001248 50.0
MMS1_k127_1071524_55 Thiamine-phosphate synthase K22206 - - 0.0002481 49.0
MMS1_k127_1071524_56 cyclin-dependent protein serine/threonine kinase activity K02087,K02206,K07760 GO:0000003,GO:0000082,GO:0000086,GO:0000278,GO:0000307,GO:0000902,GO:0003006,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004693,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006275,GO:0006325,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0007275,GO:0007346,GO:0008150,GO:0008152,GO:0008284,GO:0009058,GO:0009059,GO:0009653,GO:0009719,GO:0009725,GO:0009755,GO:0009790,GO:0009791,GO:0009793,GO:0009826,GO:0009888,GO:0009889,GO:0009934,GO:0009987,GO:0010016,GO:0010033,GO:0010103,GO:0010154,GO:0010374,GO:0010376,GO:0010389,GO:0010440,GO:0010444,GO:0010468,GO:0010556,GO:0010564,GO:0016043,GO:0016049,GO:0016301,GO:0016310,GO:0016569,GO:0016570,GO:0016572,GO:0016740,GO:0016772,GO:0016773,GO:0019219,GO:0019222,GO:0019538,GO:0022402,GO:0022414,GO:0022603,GO:0023052,GO:0030154,GO:0030332,GO:0031323,GO:0031326,GO:0032501,GO:0032502,GO:0032870,GO:0032875,GO:0032989,GO:0032991,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0042023,GO:0042127,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0044770,GO:0044772,GO:0044786,GO:0044839,GO:0044843,GO:0046483,GO:0046777,GO:0048316,GO:0048366,GO:0048367,GO:0048509,GO:0048518,GO:0048522,GO:0048589,GO:0048608,GO:0048646,GO:0048731,GO:0048825,GO:0048827,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051239,GO:0051276,GO:0051716,GO:0051726,GO:0060255,GO:0060560,GO:0061458,GO:0061695,GO:0065007,GO:0070887,GO:0071310,GO:0071495,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0090558,GO:0090626,GO:0090627,GO:0090698,GO:0097472,GO:0099402,GO:0140096,GO:1901360,GO:1901564,GO:1901576,GO:1901987,GO:1901990,GO:1902494,GO:1902554,GO:1902749,GO:1902806,GO:1902911,GO:1903047,GO:1990234,GO:2000026,GO:2000037,GO:2000112 2.7.11.22,2.7.11.23 0.0004217 42.0
MMS1_k127_1071524_57 - - - - 0.0007889 49.0
MMS1_k127_1071524_58 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000877 44.0
MMS1_k127_1071524_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 342.0
MMS1_k127_1071524_7 NADH ubiquinone oxidoreductase 49 kD subunit 7 K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 330.0
MMS1_k127_1071524_8 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 314.0
MMS1_k127_1071524_9 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 310.0
MMS1_k127_1126226_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 340.0
MMS1_k127_1126226_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002578 244.0
MMS1_k127_1126226_2 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000001375 222.0
MMS1_k127_1126226_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000008376 147.0
MMS1_k127_1141933_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 1.23e-217 689.0
MMS1_k127_1141933_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 521.0
MMS1_k127_1141933_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000002754 251.0
MMS1_k127_1141933_11 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
MMS1_k127_1141933_12 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000006592 249.0
MMS1_k127_1141933_13 Arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000004919 218.0
MMS1_k127_1141933_14 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000273 214.0
MMS1_k127_1141933_15 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000000000000000000000000001695 212.0
MMS1_k127_1141933_16 secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000009261 212.0
MMS1_k127_1141933_17 NUDIX domain K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000009822 197.0
MMS1_k127_1141933_18 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000001287 190.0
MMS1_k127_1141933_19 RNA binding S1 domain protein K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000005179 173.0
MMS1_k127_1141933_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 447.0
MMS1_k127_1141933_20 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000005134 159.0
MMS1_k127_1141933_21 MafB19-like deaminase - - - 0.000000000000000000000000000000000000001021 152.0
MMS1_k127_1141933_22 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000005504 154.0
MMS1_k127_1141933_23 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000009418 140.0
MMS1_k127_1141933_24 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.00000000000000000000000000000000007442 141.0
MMS1_k127_1141933_25 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000003456 127.0
MMS1_k127_1141933_26 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000425 133.0
MMS1_k127_1141933_27 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002893 129.0
MMS1_k127_1141933_28 Glycosyltransferase like family 2 - - - 0.00000000000000000000000002179 120.0
MMS1_k127_1141933_29 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000001447 107.0
MMS1_k127_1141933_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 404.0
MMS1_k127_1141933_30 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.00000000000000000000006215 103.0
MMS1_k127_1141933_31 Methyltransferase domain - - - 0.0000000000000000000004236 103.0
MMS1_k127_1141933_32 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000006095 102.0
MMS1_k127_1141933_33 extracellular matrix structural constituent - - - 0.0000000000000005832 90.0
MMS1_k127_1141933_34 radical SAM K06871 - - 0.000000000000001532 88.0
MMS1_k127_1141933_35 ABC-2 family transporter protein K01992 - - 0.00000000000006666 83.0
MMS1_k127_1141933_36 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000004577 64.0
MMS1_k127_1141933_38 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000002775 53.0
MMS1_k127_1141933_39 Pfam:DUF552 K09152 - - 0.0000008943 55.0
MMS1_k127_1141933_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 337.0
MMS1_k127_1141933_40 CAAX amino terminal protease family K07052 - - 0.00000183 58.0
MMS1_k127_1141933_41 - - - - 0.00001025 51.0
MMS1_k127_1141933_42 membrane-bound mannosyltransferase - - - 0.00001065 58.0
MMS1_k127_1141933_43 SMART Nucleotide binding protein, PINc K07158 - - 0.00007388 50.0
MMS1_k127_1141933_44 prefoldin K04797 GO:0001654,GO:0003674,GO:0003712,GO:0003714,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006355,GO:0007275,GO:0007423,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009968,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0016272,GO:0019219,GO:0019222,GO:0023051,GO:0023057,GO:0030111,GO:0030178,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032501,GO:0032502,GO:0032991,GO:0043010,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060041,GO:0060255,GO:0060828,GO:0065007,GO:0080090,GO:0090090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0003329 49.0
MMS1_k127_1141933_45 exo-alpha-(2->6)-sialidase activity - - - 0.0008155 51.0
MMS1_k127_1141933_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 335.0
MMS1_k127_1141933_6 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
MMS1_k127_1141933_7 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003387 272.0
MMS1_k127_1141933_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004946 276.0
MMS1_k127_1141933_9 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001409 260.0
MMS1_k127_138107_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 2.018e-197 633.0
MMS1_k127_138107_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 362.0
MMS1_k127_138107_10 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000006199 110.0
MMS1_k127_138107_11 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000001257 101.0
MMS1_k127_138107_12 Glycosyl transferase family 21 K00694 - 2.4.1.12 0.000000000000000000002138 109.0
MMS1_k127_138107_13 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000004607 91.0
MMS1_k127_138107_14 Protein of unknown function (DUF1634) - - - 0.0000000000001701 75.0
MMS1_k127_138107_15 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000003186 68.0
MMS1_k127_138107_16 Protein of unknown function (DUF424) K09148 - - 0.0000001693 59.0
MMS1_k127_138107_17 - - - - 0.000000343 64.0
MMS1_k127_138107_18 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products K03552 - 3.1.22.4 0.000001957 55.0
MMS1_k127_138107_19 Proline dehydrogenase K00318 GO:0000166,GO:0003674,GO:0003824,GO:0004657,GO:0005488,GO:0006082,GO:0006520,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.00008109 53.0
MMS1_k127_138107_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 291.0
MMS1_k127_138107_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000662 269.0
MMS1_k127_138107_4 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000001167 217.0
MMS1_k127_138107_5 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000001141 184.0
MMS1_k127_138107_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000001422 148.0
MMS1_k127_138107_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000002879 126.0
MMS1_k127_138107_8 RNHCP domain - - - 0.00000000000000000000000004683 110.0
MMS1_k127_138107_9 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000003127 112.0
MMS1_k127_145406_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 4.947e-242 767.0
MMS1_k127_145406_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 5.124e-215 682.0
MMS1_k127_145406_10 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 353.0
MMS1_k127_145406_11 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 348.0
MMS1_k127_145406_12 carbamoyl transferase K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 300.0
MMS1_k127_145406_13 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002366 290.0
MMS1_k127_145406_14 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005989 267.0
MMS1_k127_145406_15 AhpC/TSA family K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000003708 252.0
MMS1_k127_145406_16 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000258 221.0
MMS1_k127_145406_17 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000003072 220.0
MMS1_k127_145406_18 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000004773 194.0
MMS1_k127_145406_19 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000602 205.0
MMS1_k127_145406_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 8.706e-210 684.0
MMS1_k127_145406_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000004007 181.0
MMS1_k127_145406_21 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001446 160.0
MMS1_k127_145406_22 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000002281 150.0
MMS1_k127_145406_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000002521 143.0
MMS1_k127_145406_24 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000001017 144.0
MMS1_k127_145406_25 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000005191 153.0
MMS1_k127_145406_26 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.0000000000000000000000000000000005655 145.0
MMS1_k127_145406_27 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000004333 135.0
MMS1_k127_145406_28 PFAM Peptidase - - - 0.00000000000000000000000000000004893 134.0
MMS1_k127_145406_29 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002052 125.0
MMS1_k127_145406_3 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.347e-208 666.0
MMS1_k127_145406_30 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000002231 124.0
MMS1_k127_145406_31 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000426 117.0
MMS1_k127_145406_32 amine dehydrogenase activity - - - 0.0000000000000000000003774 114.0
MMS1_k127_145406_33 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000008676 108.0
MMS1_k127_145406_34 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000005478 110.0
MMS1_k127_145406_35 Belongs to the eukaryotic ribosomal protein eL30 family K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000006485 93.0
MMS1_k127_145406_36 Sam-dependent methyltransferase K06968 - 2.1.1.186 0.0000000000000000003115 99.0
MMS1_k127_145406_37 membrane - - - 0.000000000000003414 79.0
MMS1_k127_145406_38 ATP synthase subunit C K02124 - - 0.00000000000001593 75.0
MMS1_k127_145406_39 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.0000000000002573 75.0
MMS1_k127_145406_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 600.0
MMS1_k127_145406_40 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000005886 72.0
MMS1_k127_145406_41 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000006346 75.0
MMS1_k127_145406_42 Glycosyl transferase 4-like - - - 0.000000000003547 78.0
MMS1_k127_145406_43 Uncharacterised protein family UPF0047 - - - 0.000000003113 69.0
MMS1_k127_145406_44 Laminin G domain - - - 0.000000008287 70.0
MMS1_k127_145406_45 guanyl-nucleotide exchange factor activity K00504,K01181,K06889,K07004,K12548 - 1.14.17.3,3.2.1.8 0.0000001823 65.0
MMS1_k127_145406_46 Binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000343 53.0
MMS1_k127_145406_47 Protein conserved in bacteria - - - 0.0000004164 64.0
MMS1_k127_145406_48 - - - - 0.0000004926 57.0
MMS1_k127_145406_49 Concanavalin A-like lectin/glucanases superfamily - - - 0.000005179 60.0
MMS1_k127_145406_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 574.0
MMS1_k127_145406_50 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000008741 49.0
MMS1_k127_145406_51 PFAM Transcription factor CBF NF-Y - - - 0.00004319 48.0
MMS1_k127_145406_52 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0003573 48.0
MMS1_k127_145406_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 480.0
MMS1_k127_145406_7 Psort location Cytoplasmic, score 8.87 K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 407.0
MMS1_k127_145406_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 357.0
MMS1_k127_145406_9 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 357.0
MMS1_k127_1524865_0 transferase activity, transferring glycosyl groups K00752,K14666 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006807,GO:0007155,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0019752,GO:0022607,GO:0022610,GO:0030198,GO:0030203,GO:0030212,GO:0030213,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0042710,GO:0043062,GO:0043170,GO:0043436,GO:0044010,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0045226,GO:0046379,GO:0046394,GO:0050501,GO:0051704,GO:0071704,GO:0071840,GO:0071944,GO:0085029,GO:0090605,GO:0090609,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903510 2.4.1.212 0.000000000000000000000000000000000000000000000000000000000000004763 233.0
MMS1_k127_1524865_1 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000001097 144.0
MMS1_k127_1524865_2 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001508 132.0
MMS1_k127_1524865_3 Polysaccharide deacetylase - - - 0.000000000000000000000007984 113.0
MMS1_k127_1524865_4 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000003563 88.0
MMS1_k127_1524865_5 Parallel beta-helix repeats - - - 0.000000000002844 81.0
MMS1_k127_1524865_6 transferase activity, transferring glycosyl groups K01181,K08300,K08301 - 3.1.26.12,3.2.1.8 0.000001499 62.0
MMS1_k127_1524865_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0004518 52.0
MMS1_k127_1536550_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 5.913e-247 788.0
MMS1_k127_1536550_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 1.404e-196 630.0
MMS1_k127_1536550_10 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 281.0
MMS1_k127_1536550_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003998 282.0
MMS1_k127_1536550_12 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000819 276.0
MMS1_k127_1536550_13 PFAM ABC transporter K02003,K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000002366 239.0
MMS1_k127_1536550_14 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001453 228.0
MMS1_k127_1536550_15 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000001263 193.0
MMS1_k127_1536550_16 Protein of unknown function (DUF981) K08980 - - 0.000000000000000000000000000000000000000000000003385 179.0
MMS1_k127_1536550_17 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000003236 138.0
MMS1_k127_1536550_18 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000007532 120.0
MMS1_k127_1536550_19 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000002138 115.0
MMS1_k127_1536550_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 492.0
MMS1_k127_1536550_20 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000000002551 103.0
MMS1_k127_1536550_21 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000268 110.0
MMS1_k127_1536550_22 Putative heavy-metal-binding - - - 0.0000000000000000000002882 101.0
MMS1_k127_1536550_23 BUD32 protein kinase K08851 GO:0000003,GO:0000166,GO:0000278,GO:0000281,GO:0000282,GO:0000408,GO:0000722,GO:0000723,GO:0000910,GO:0002949,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006312,GO:0006355,GO:0006357,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007049,GO:0007163,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009653,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0019954,GO:0022402,GO:0030010,GO:0030154,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032200,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043934,GO:0043936,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0045944,GO:0046483,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051276,GO:0051301,GO:0060249,GO:0060255,GO:0061640,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902680,GO:1903047,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.11.1 0.000000000000000005948 93.0
MMS1_k127_1536550_24 Belongs to the snRNP Sm proteins family K04796 - - 0.00000000000000004548 82.0
MMS1_k127_1536550_25 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000006421 78.0
MMS1_k127_1536550_26 serine-type endopeptidase activity - - - 0.0000000000004036 81.0
MMS1_k127_1536550_27 - - - - 0.000000000001478 73.0
MMS1_k127_1536550_28 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.00000000001783 76.0
MMS1_k127_1536550_29 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000002064 58.0
MMS1_k127_1536550_3 Belongs to the MCM family K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 492.0
MMS1_k127_1536550_30 Belongs to the glycosyl hydrolase 32 family K03332 - 3.2.1.80 0.000001973 58.0
MMS1_k127_1536550_31 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000003151 52.0
MMS1_k127_1536550_32 - K02928 - - 0.000003781 49.0
MMS1_k127_1536550_33 Presenilin, signal peptide peptidase, family - - - 0.0003659 52.0
MMS1_k127_1536550_4 Belongs to the RNA polymerase beta chain family K03045 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 440.0
MMS1_k127_1536550_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 367.0
MMS1_k127_1536550_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 354.0
MMS1_k127_1536550_7 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 345.0
MMS1_k127_1536550_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 287.0
MMS1_k127_1536550_9 C-terminal region of MMR_HSR1 domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009336 285.0
MMS1_k127_1760742_0 FeS assembly protein SufB K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 598.0
MMS1_k127_1760742_1 Peptidase family M1 domain K01256,K13722 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 578.0
MMS1_k127_1760742_10 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000000002246 167.0
MMS1_k127_1760742_11 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000002084 131.0
MMS1_k127_1760742_12 NUDIX domain K03574,K17816 - 3.6.1.55,3.6.1.56 0.000000000000000000000000000000496 131.0
MMS1_k127_1760742_13 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000004932 119.0
MMS1_k127_1760742_14 Lysine methyltransferase K02493 - 2.1.1.297 0.0000000000000000000000001138 114.0
MMS1_k127_1760742_15 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000008956 119.0
MMS1_k127_1760742_16 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000008577 100.0
MMS1_k127_1760742_17 COG0455 ATPases involved in chromosome partitioning K03609 - - 0.00000000000000000002667 100.0
MMS1_k127_1760742_18 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component K09015 - - 0.00000000000000004238 94.0
MMS1_k127_1760742_19 homoserine kinase activity K02204 - 2.7.1.39 0.0000000000759 73.0
MMS1_k127_1760742_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 449.0
MMS1_k127_1760742_20 alpha-ribazole phosphatase activity - - - 0.00000322 57.0
MMS1_k127_1760742_21 - - - - 0.0001491 49.0
MMS1_k127_1760742_22 Transcriptional regulator K22206 - - 0.0001851 48.0
MMS1_k127_1760742_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 427.0
MMS1_k127_1760742_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759,K22503 - 6.1.1.12,6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 404.0
MMS1_k127_1760742_5 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002931 254.0
MMS1_k127_1760742_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000005118 218.0
MMS1_k127_1760742_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000001276 194.0
MMS1_k127_1760742_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000001021 178.0
MMS1_k127_1760742_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000007061 169.0
MMS1_k127_1916119_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000003734 218.0
MMS1_k127_1916119_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000001859 218.0
MMS1_k127_1916119_2 PFAM LemA K03744 - - 0.0000000000000000000000000000000000000000000000000000001243 202.0
MMS1_k127_1916119_3 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000001147 204.0
MMS1_k127_1916119_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000008815 133.0
MMS1_k127_1916119_5 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000004822 130.0
MMS1_k127_1916119_6 - - - - 0.0000000000000000001984 91.0
MMS1_k127_1916119_7 PAC2 family K06869 - - 0.0000000000000000002335 97.0
MMS1_k127_1916119_8 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000008532 95.0
MMS1_k127_193924_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 3.634e-309 973.0
MMS1_k127_193924_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 590.0
MMS1_k127_193924_10 RNA-binding protein contains TRAM domain - - - 0.00000000006988 67.0
MMS1_k127_193924_11 PFAM Transposase DDE domain - - - 0.00000000008766 72.0
MMS1_k127_193924_12 TIGRFAM addiction module toxin, RelE StbE family K19158 - - 0.00000004095 58.0
MMS1_k127_193924_2 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 484.0
MMS1_k127_193924_3 Malate:quinone oxidoreductase (Mqo) K00116 - 1.1.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 367.0
MMS1_k127_193924_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 357.0
MMS1_k127_193924_5 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000008811 193.0
MMS1_k127_193924_6 NUDIX domain - - - 0.00000000000000000000000000004054 123.0
MMS1_k127_193924_7 PD-(D/E)XK nuclease superfamily K17815 - - 0.00000000000000007152 91.0
MMS1_k127_193924_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000305 77.0
MMS1_k127_193924_9 HAD hydrolase, family IA, variant 1 - - - 0.0000000000003129 78.0
MMS1_k127_202578_0 Cell division protein 48, CDC48, domain 2 K13525 - - 1.859e-261 823.0
MMS1_k127_202578_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 434.0
MMS1_k127_202578_10 PFAM DHHA1 domain K07097 - - 0.0000000000000000008504 98.0
MMS1_k127_202578_11 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001637 82.0
MMS1_k127_202578_12 Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl- transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome K02941 GO:0000027,GO:0002181,GO:0002182,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030684,GO:0030686,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002505 89.0
MMS1_k127_202578_13 - - - - 0.00000000002269 66.0
MMS1_k127_202578_14 AAA-like domain K06915 - - 0.0000000000888 74.0
MMS1_k127_202578_15 Protein of unknown function (DUF2666) - - - 0.000000937 60.0
MMS1_k127_202578_16 COGs COG4741 secreted endonuclease distantly related to Holliday junction resolvase - - - 0.00001035 55.0
MMS1_k127_202578_17 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0001562 45.0
MMS1_k127_202578_18 4Fe-4S dicluster domain K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.0008264 43.0
MMS1_k127_202578_19 4Fe-4S dicluster domain - - - 0.0008573 46.0
MMS1_k127_202578_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 380.0
MMS1_k127_202578_3 type II secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 323.0
MMS1_k127_202578_4 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000168 202.0
MMS1_k127_202578_5 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000009731 181.0
MMS1_k127_202578_6 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001781 149.0
MMS1_k127_202578_7 hmm pf00665 K07498 - - 0.000000000000000000000004292 116.0
MMS1_k127_202578_8 K homology RNA-binding domain K06961 - - 0.0000000000000000000001003 106.0
MMS1_k127_202578_9 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000001258 96.0
MMS1_k127_2129032_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.349e-226 717.0
MMS1_k127_2129032_1 NADP-dependent dehydrogenase of the nED (non- phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D- glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3- phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes K18128 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006081,GO:0006082,GO:0006090,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009255,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016620,GO:0016903,GO:0019637,GO:0019682,GO:0019752,GO:0022607,GO:0032787,GO:0042802,GO:0042803,GO:0043436,GO:0043796,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0061678,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901575 1.2.1.89 2.303e-216 681.0
MMS1_k127_2129032_10 mRNA catabolic process K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003242 261.0
MMS1_k127_2129032_11 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000002119 212.0
MMS1_k127_2129032_12 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000002155 205.0
MMS1_k127_2129032_13 Cupin domain - - - 0.000000000000000000000000000000000000000000000000005991 183.0
MMS1_k127_2129032_14 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000278 186.0
MMS1_k127_2129032_15 - - - - 0.0000000000000000000000000000000000000000000000001458 183.0
MMS1_k127_2129032_16 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000005338 177.0
MMS1_k127_2129032_17 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000008286 189.0
MMS1_k127_2129032_18 Uncharacterised protein family (UPF0227) K06889 - - 0.000000000000000000000000000000000000000000000592 175.0
MMS1_k127_2129032_19 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000006143 175.0
MMS1_k127_2129032_2 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 550.0
MMS1_k127_2129032_20 acetyltransferase - - - 0.0000000000000000000000000000000000000000000122 168.0
MMS1_k127_2129032_21 lyase activity K01714,K18127 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0008150,GO:0008152,GO:0008674,GO:0008675,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 4.1.2.51,4.3.3.7 0.0000000000000000000000000000000000000000004066 169.0
MMS1_k127_2129032_22 PFAM Glycosyl transferase family 2 K19003 - 2.4.1.336 0.00000000000000000000000000000000000004908 157.0
MMS1_k127_2129032_24 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000009964 145.0
MMS1_k127_2129032_25 Involved in protein export K03074 - - 0.00000000000000000000000000000005736 139.0
MMS1_k127_2129032_26 Methyltransferase - - - 0.000000000000000000000000003002 118.0
MMS1_k127_2129032_27 Glyoxalase-like domain K06996 - - 0.00000000000000002492 87.0
MMS1_k127_2129032_28 Type II secretion system K07333 - - 0.0000000000000003616 90.0
MMS1_k127_2129032_29 NMD3 family K07562 - - 0.000000000000007313 82.0
MMS1_k127_2129032_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K05308 GO:0003674,GO:0003824,GO:0008869,GO:0016829,GO:0016835,GO:0016836,GO:0047929 4.2.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 483.0
MMS1_k127_2129032_30 extracellular matrix structural constituent - - - 0.0000000000001491 81.0
MMS1_k127_2129032_31 oligosaccharyl transferase activity - - - 0.0000000000002763 83.0
MMS1_k127_2129032_32 Type II secretion system (T2SS), protein F K07333 - - 0.000000000001193 80.0
MMS1_k127_2129032_33 NUDIX domain - - - 0.00000000007246 70.0
MMS1_k127_2129032_34 - - - - 0.000000000222 62.0
MMS1_k127_2129032_36 - - - - 0.0000000165 59.0
MMS1_k127_2129032_38 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000001308 57.0
MMS1_k127_2129032_4 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 424.0
MMS1_k127_2129032_40 GNAT family - - - 0.00003355 52.0
MMS1_k127_2129032_5 GTP-binding protein HSR1-related K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 340.0
MMS1_k127_2129032_6 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 336.0
MMS1_k127_2129032_7 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway K00068,K18124,K18125 GO:0000166,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005515,GO:0005534,GO:0005536,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006012,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019320,GO:0019388,GO:0019595,GO:0022607,GO:0030246,GO:0033498,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046430,GO:0046872,GO:0046914,GO:0046983,GO:0047910,GO:0047936,GO:0048029,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051262,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.140,1.1.1.359,1.1.1.360 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003343 288.0
MMS1_k127_2129032_8 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009996 272.0
MMS1_k127_2129032_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000001729 265.0
MMS1_k127_2195751_0 type I restriction-modification system, methyltransferase subunit K03427 - 2.1.1.72 3.152e-269 854.0
MMS1_k127_2195751_1 Radical SAM domain protein K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 570.0
MMS1_k127_2195751_10 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001028 275.0
MMS1_k127_2195751_11 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000009349 278.0
MMS1_k127_2195751_12 Metallopeptidase family M24 K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001336 272.0
MMS1_k127_2195751_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000002281 260.0
MMS1_k127_2195751_14 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004557 250.0
MMS1_k127_2195751_15 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000001048 217.0
MMS1_k127_2195751_16 SMART helix-turn-helix domain protein K07731 - - 0.0000000000000000000000000000000000000000000000000000000007536 209.0
MMS1_k127_2195751_17 SMART metal-dependent phosphohydrolase, HD region K06885 - - 0.000000000000000000000000000000000000000000000000000001524 207.0
MMS1_k127_2195751_18 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000332 192.0
MMS1_k127_2195751_19 Domain of unknown function (DUF929) - - - 0.0000000000000000000000000000000000000000000000003307 186.0
MMS1_k127_2195751_2 regulation of single-species biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 473.0
MMS1_k127_2195751_20 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000001318 180.0
MMS1_k127_2195751_21 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000148 179.0
MMS1_k127_2195751_22 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000107 169.0
MMS1_k127_2195751_23 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000003352 158.0
MMS1_k127_2195751_24 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000001047 148.0
MMS1_k127_2195751_25 COG1226 Kef-type K transport systems K10716 - - 0.00000000000000000000000000000000000004504 153.0
MMS1_k127_2195751_26 Belongs to the peptidase M50B family - GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000003362 139.0
MMS1_k127_2195751_27 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000005476 136.0
MMS1_k127_2195751_28 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000001434 129.0
MMS1_k127_2195751_29 Inositol monophosphatase family - - - 0.0000000000000000000000000000002289 133.0
MMS1_k127_2195751_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 434.0
MMS1_k127_2195751_30 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000003 139.0
MMS1_k127_2195751_31 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000005196 124.0
MMS1_k127_2195751_32 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000002467 116.0
MMS1_k127_2195751_33 Protein of unknown function (DUF460) K09150 - - 0.00000000000000000000007045 105.0
MMS1_k127_2195751_34 HIT domain - - - 0.000000000000000000005338 98.0
MMS1_k127_2195751_35 Pfam:KaiC K08482 - - 0.000000000000000001431 94.0
MMS1_k127_2195751_36 VKc - - - 0.000000000000000003937 89.0
MMS1_k127_2195751_37 PFAM Translin K07477 - - 0.0000000000000000502 88.0
MMS1_k127_2195751_38 acid binding OB-fold tRNA helicase-type K07463 - - 0.000000000000001678 89.0
MMS1_k127_2195751_39 PFAM Lon protease (S16) C-terminal proteolytic domain K06870 - - 0.0000000000002777 83.0
MMS1_k127_2195751_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
MMS1_k127_2195751_40 PFAM Aminoglycoside phosphotransferase - - - 0.000000000001098 79.0
MMS1_k127_2195751_41 membrane K08978 - - 0.000000000003221 77.0
MMS1_k127_2195751_42 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000008457 69.0
MMS1_k127_2195751_43 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.00000000002029 73.0
MMS1_k127_2195751_44 Domain of unknown function (DUF1610) K07580 - - 0.00000000152 60.0
MMS1_k127_2195751_45 NUDIX domain K08310 - 3.6.1.67 0.000002558 56.0
MMS1_k127_2195751_46 DNA binding K06875 - - 0.000005463 53.0
MMS1_k127_2195751_47 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000006696 52.0
MMS1_k127_2195751_48 PRC-barrel domain - - - 0.00001675 50.0
MMS1_k127_2195751_49 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0004585 44.0
MMS1_k127_2195751_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 414.0
MMS1_k127_2195751_50 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.0006215 44.0
MMS1_k127_2195751_51 Domain of unknown function DUF87 K19175 - - 0.0009866 50.0
MMS1_k127_2195751_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 402.0
MMS1_k127_2195751_7 Pfam:DUF650 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 366.0
MMS1_k127_2195751_8 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 320.0
MMS1_k127_2195751_9 ERCC4 domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 310.0
MMS1_k127_2330703_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 374.0
MMS1_k127_2330703_1 Polysaccharide biosynthesis protein K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 362.0
MMS1_k127_2330703_10 Rubrerythrin - - - 0.00000000000000000000000002921 120.0
MMS1_k127_2330703_11 PFAM Glycosyl transferases group 1 K19002 - 2.4.1.337 0.0000000000000000000009341 108.0
MMS1_k127_2330703_12 Glycosyl hydrolases family 8 - - - 0.000000000000000001507 102.0
MMS1_k127_2330703_13 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000002223 93.0
MMS1_k127_2330703_14 Methyltransferase FkbM domain - - - 0.000000000000000002954 95.0
MMS1_k127_2330703_15 PFAM Glycosyl transferase family 2 - - - 0.000000000000000009458 93.0
MMS1_k127_2330703_16 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0000000000000001721 97.0
MMS1_k127_2330703_17 - - - - 0.0000000000000004143 83.0
MMS1_k127_2330703_18 Methionine biosynthesis protein MetW - - - 0.00000002025 62.0
MMS1_k127_2330703_19 transferase activity, transferring glycosyl groups K05946,K16701,K17249 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006464,GO:0006486,GO:0006487,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0008653,GO:0008921,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035250,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.4.1.187,2.4.1.292 0.000003144 59.0
MMS1_k127_2330703_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 351.0
MMS1_k127_2330703_20 SprB repeat - - - 0.0000792 59.0
MMS1_k127_2330703_3 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007916 267.0
MMS1_k127_2330703_4 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006268 251.0
MMS1_k127_2330703_5 Enoyl-(Acyl carrier protein) reductase K14189 - - 0.0000000000000000000000000000000000000000000000000000000000001262 220.0
MMS1_k127_2330703_6 zinc finger - - - 0.0000000000000000000000000000000000000000007422 164.0
MMS1_k127_2330703_7 IPT/TIG domain - - - 0.000000000000000000000000000000000000001923 171.0
MMS1_k127_2330703_8 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.0000000000000000000000000000000001054 134.0
MMS1_k127_2330703_9 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000001696 144.0
MMS1_k127_2377142_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 627.0
MMS1_k127_2377142_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 456.0
MMS1_k127_2377142_10 Protoglobin - - - 0.0000000000000001015 89.0
MMS1_k127_2377142_11 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000006092 72.0
MMS1_k127_2377142_12 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000001315 59.0
MMS1_k127_2377142_2 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001344 281.0
MMS1_k127_2377142_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000002809 252.0
MMS1_k127_2377142_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000005948 147.0
MMS1_k127_2377142_5 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000001526 142.0
MMS1_k127_2377142_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000001159 138.0
MMS1_k127_2377142_7 acr, cog1430 K09005 - - 0.000000000000000000009936 96.0
MMS1_k127_2377142_8 Segregation and condensation protein ScpA K05896 - - 0.00000000000000000003521 99.0
MMS1_k127_2377142_9 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000006621 89.0
MMS1_k127_2392066_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000003018 174.0
MMS1_k127_2392066_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000001595 103.0
MMS1_k127_2473300_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.88e-211 694.0
MMS1_k127_2473300_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 533.0
MMS1_k127_2473300_10 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000002543 235.0
MMS1_k127_2473300_11 MjaI restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000002185 220.0
MMS1_k127_2473300_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.0000000000000000000000000000000000000000000385 167.0
MMS1_k127_2473300_13 N-terminal domain of galactosyltransferase - - - 0.0000000000000000000000000000000000000000003192 166.0
MMS1_k127_2473300_15 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000006614 162.0
MMS1_k127_2473300_16 Hydrolase, NUDIX family K01515 - 3.6.1.13 0.000000000000000000000000009095 117.0
MMS1_k127_2473300_17 metal-sulfur cluster biosynthetic - - - 0.00000000000000000000000004252 111.0
MMS1_k127_2473300_18 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000003572 104.0
MMS1_k127_2473300_19 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000001291 75.0
MMS1_k127_2473300_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 432.0
MMS1_k127_2473300_20 acetyltransferase K06975 - - 0.00000000001378 67.0
MMS1_k127_2473300_21 Signal peptidase K13280 - 3.4.21.89 0.000002336 59.0
MMS1_k127_2473300_22 Type IV secretion-system coupling protein DNA-binding domain K06915 - - 0.00005983 56.0
MMS1_k127_2473300_23 Periplasmic copper-binding protein (NosD) - - - 0.0002758 55.0
MMS1_k127_2473300_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 381.0
MMS1_k127_2473300_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 373.0
MMS1_k127_2473300_5 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 336.0
MMS1_k127_2473300_6 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 359.0
MMS1_k127_2473300_7 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 337.0
MMS1_k127_2473300_8 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 320.0
MMS1_k127_2473300_9 methylthiotransferase activity K15865 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 309.0
MMS1_k127_2629032_0 Heat shock 70 kDa protein K04043 - - 5.26e-242 762.0
MMS1_k127_2629032_1 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 537.0
MMS1_k127_2629032_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000007801 105.0
MMS1_k127_2629032_11 Phosphate acyltransferases - - - 0.00000000000000000007408 98.0
MMS1_k127_2629032_12 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000003269 88.0
MMS1_k127_2629032_13 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000001022 84.0
MMS1_k127_2629032_14 This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand K04802 - - 0.000000000000003241 85.0
MMS1_k127_2629032_15 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000003859 80.0
MMS1_k127_2629032_16 Protein of unknown function (DUF357) K09728 - - 0.00000000003097 67.0
MMS1_k127_2629032_17 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000002467 64.0
MMS1_k127_2629032_18 Bacterial regulatory protein, arsR family - - - 0.0000000007154 66.0
MMS1_k127_2629032_19 Parallel beta-helix repeats - - - 0.00000001273 68.0
MMS1_k127_2629032_2 Beta-Casp domain K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 302.0
MMS1_k127_2629032_20 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000001359 60.0
MMS1_k127_2629032_21 Concanavalin A-like lectin/glucanases superfamily - - - 0.00001352 56.0
MMS1_k127_2629032_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
MMS1_k127_2629032_4 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.00000000000000000000000000000000000000000000000000000000001183 214.0
MMS1_k127_2629032_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000002922 208.0
MMS1_k127_2629032_6 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000001107 200.0
MMS1_k127_2629032_7 Histidine kinase - - - 0.000000000000000000000000000000000000000005163 178.0
MMS1_k127_2629032_8 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000004726 117.0
MMS1_k127_2629032_9 structural constituent of ribosome K02907 - - 0.00000000000000000000003403 105.0
MMS1_k127_2642149_0 Beta-Casp domain K07041 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 596.0
MMS1_k127_2642149_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 501.0
MMS1_k127_2642149_10 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000002184 213.0
MMS1_k127_2642149_11 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000007651 197.0
MMS1_k127_2642149_12 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000001085 193.0
MMS1_k127_2642149_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.0000000000000000000000000000000000000000000000003848 183.0
MMS1_k127_2642149_14 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000002155 165.0
MMS1_k127_2642149_15 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000008639 173.0
MMS1_k127_2642149_16 SMART RNA polymerase, RpoA D Rpb3-type K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000001364 139.0
MMS1_k127_2642149_17 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000002661 132.0
MMS1_k127_2642149_19 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000004073 116.0
MMS1_k127_2642149_2 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 408.0
MMS1_k127_2642149_20 Serine hydrolase K07002 - - 0.0000000000000000000000000005067 120.0
MMS1_k127_2642149_21 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000001441 126.0
MMS1_k127_2642149_22 phosphoribosyl-ATP pyrophosphohydrolase - - - 0.00000000000000000000003289 102.0
MMS1_k127_2642149_23 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000002481 97.0
MMS1_k127_2642149_24 PFAM Nucleotide-binding protein, PIN domain - - - 0.00000000000000001533 94.0
MMS1_k127_2642149_25 PFAM Polysaccharide biosynthesis protein - - - 0.0000000000000001616 93.0
MMS1_k127_2642149_26 PFAM helix-turn-helix domain protein K03627 - - 0.0000000000000001814 85.0
MMS1_k127_2642149_27 - - - - 0.000000000000000562 82.0
MMS1_k127_2642149_29 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000001595 83.0
MMS1_k127_2642149_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 361.0
MMS1_k127_2642149_30 DNA-sulfur modification-associated - - - 0.00000000004169 75.0
MMS1_k127_2642149_32 carbonic anhydrase K01673 - 4.2.1.1 0.000000001436 68.0
MMS1_k127_2642149_33 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000001441 66.0
MMS1_k127_2642149_34 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000001576 56.0
MMS1_k127_2642149_35 NUDIX hydrolase - - - 0.0000002249 59.0
MMS1_k127_2642149_36 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000007993 53.0
MMS1_k127_2642149_37 Protein of unknown function (DUF655) K07572 - - 0.0000168 47.0
MMS1_k127_2642149_38 Phage integrase family - - - 0.00003212 55.0
MMS1_k127_2642149_39 RNA-binding protein contains TRAM domain - - - 0.00004901 49.0
MMS1_k127_2642149_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 343.0
MMS1_k127_2642149_40 MazG nucleotide pyrophosphohydrolase domain - - - 0.00005988 53.0
MMS1_k127_2642149_41 PFAM glycosyl transferase family 39 - - - 0.0005229 53.0
MMS1_k127_2642149_5 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 366.0
MMS1_k127_2642149_6 tRNA synthetases class I (W and Y) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 297.0
MMS1_k127_2642149_7 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000003697 224.0
MMS1_k127_2642149_8 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001015 227.0
MMS1_k127_2642149_9 AAA-like domain - - - 0.000000000000000000000000000000000000000000000000000000000001961 229.0
MMS1_k127_2694124_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 351.0
MMS1_k127_2694124_1 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001652 269.0
MMS1_k127_2694124_10 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000005703 78.0
MMS1_k127_2694124_11 COG NOG14600 non supervised orthologous group - - - 0.0000000002941 66.0
MMS1_k127_2694124_12 Cell wall-associated hydrolase - - - 0.0000004239 52.0
MMS1_k127_2694124_13 - - - - 0.000001289 51.0
MMS1_k127_2694124_14 - - - - 0.000003222 49.0
MMS1_k127_2694124_2 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000594 262.0
MMS1_k127_2694124_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000002665 216.0
MMS1_k127_2694124_4 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000004057 195.0
MMS1_k127_2694124_5 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000003687 147.0
MMS1_k127_2694124_6 EamA-like transporter family - - - 0.0000000000000000000002736 107.0
MMS1_k127_2694124_7 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000558 98.0
MMS1_k127_2694124_8 Glycosyl hydrolases family 8 - - - 0.000000000000002248 91.0
MMS1_k127_2694124_9 AAA-like domain K06915 - - 0.00000000000009746 84.0
MMS1_k127_288537_0 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005812 257.0
MMS1_k127_288537_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000003199 202.0
MMS1_k127_288537_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000009625 183.0
MMS1_k127_288537_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000005407 138.0
MMS1_k127_288537_4 PFAM elongation factor Tu, domain 2 protein - - - 0.00000000000000000000000000002619 128.0
MMS1_k127_288537_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000003965 94.0
MMS1_k127_288537_6 Methyltransferase domain protein - - - 0.0000007491 59.0
MMS1_k127_288537_7 Epoxide hydrolase 2 K08726,K10089 GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006633,GO:0006690,GO:0006725,GO:0006793,GO:0006796,GO:0006805,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007031,GO:0007600,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008217,GO:0008610,GO:0009056,GO:0009058,GO:0009410,GO:0009636,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015031,GO:0015643,GO:0015833,GO:0016043,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0017144,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019369,GO:0019373,GO:0019439,GO:0019725,GO:0019752,GO:0030003,GO:0030258,GO:0031907,GO:0031974,GO:0032501,GO:0032787,GO:0033036,GO:0033365,GO:0033559,GO:0034613,GO:0035150,GO:0035296,GO:0042221,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042759,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045777,GO:0046272,GO:0046394,GO:0046483,GO:0046839,GO:0046872,GO:0046907,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050801,GO:0050877,GO:0050880,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070887,GO:0071466,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072330,GO:0072503,GO:0072507,GO:0072593,GO:0072594,GO:0072662,GO:0072663,GO:0080090,GO:0090066,GO:0090181,GO:0097176,GO:0097746,GO:0097755,GO:0098771,GO:1900673,GO:1901360,GO:1901361,GO:1901568,GO:1901575,GO:1901576 3.1.3.76,3.3.2.10 0.000002293 52.0
MMS1_k127_29112_0 NUDIX domain K01823 - 5.3.3.2 0.000000000000000000005536 98.0
MMS1_k127_29112_1 Methyltransferase domain - - - 0.0000000000000000006827 94.0
MMS1_k127_29112_2 HAD-hyrolase-like K07025 - - 0.0000002139 57.0
MMS1_k127_29112_3 AAA domain - - - 0.00006845 52.0
MMS1_k127_29112_4 Transposase DDE domain - - - 0.0001026 48.0
MMS1_k127_407720_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 310.0
MMS1_k127_490312_0 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004777 280.0
MMS1_k127_490312_1 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000002012 253.0
MMS1_k127_728943_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 1.505e-203 651.0
MMS1_k127_728943_1 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 394.0
MMS1_k127_728943_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 356.0
MMS1_k127_728943_3 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000006786 246.0
MMS1_k127_728943_4 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000003858 82.0
MMS1_k127_728943_5 Protein of unknown function (DUF1059) - - - 0.0000000005304 61.0
MMS1_k127_85296_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 5.134e-290 927.0
MMS1_k127_85296_1 DEAD DEAH box helicase K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 4.788e-248 793.0
MMS1_k127_85296_10 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 404.0
MMS1_k127_85296_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 371.0
MMS1_k127_85296_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 368.0
MMS1_k127_85296_13 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 355.0
MMS1_k127_85296_14 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 317.0
MMS1_k127_85296_15 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 305.0
MMS1_k127_85296_16 NAD-dependent epimerase dehydratase K01784,K03274 - 5.1.3.2,5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 304.0
MMS1_k127_85296_17 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 308.0
MMS1_k127_85296_18 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000403 291.0
MMS1_k127_85296_19 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000002697 274.0
MMS1_k127_85296_2 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 1.755e-241 766.0
MMS1_k127_85296_20 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001574 263.0
MMS1_k127_85296_21 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005436 269.0
MMS1_k127_85296_22 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000186 246.0
MMS1_k127_85296_23 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000002811 254.0
MMS1_k127_85296_24 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.0000000000000000000000000000000000000000000000000000000000007423 219.0
MMS1_k127_85296_25 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000001784 216.0
MMS1_k127_85296_26 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000002712 213.0
MMS1_k127_85296_27 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000004509 212.0
MMS1_k127_85296_28 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000001578 207.0
MMS1_k127_85296_29 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000003839 214.0
MMS1_k127_85296_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.944e-230 737.0
MMS1_k127_85296_30 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000008244 191.0
MMS1_k127_85296_31 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000002849 184.0
MMS1_k127_85296_32 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000002743 170.0
MMS1_k127_85296_33 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000001062 160.0
MMS1_k127_85296_34 PAC2 family K07159 - - 0.00000000000000000000000000000000000000008509 160.0
MMS1_k127_85296_35 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000001186 165.0
MMS1_k127_85296_36 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000009216 153.0
MMS1_k127_85296_37 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000008126 151.0
MMS1_k127_85296_38 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000006805 152.0
MMS1_k127_85296_39 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000007841 151.0
MMS1_k127_85296_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.126e-220 702.0
MMS1_k127_85296_40 Lycopene cyclase protein - - - 0.0000000000000000000000000000000000008326 153.0
MMS1_k127_85296_41 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000209 139.0
MMS1_k127_85296_42 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000004601 138.0
MMS1_k127_85296_43 COG0668 Small-conductance mechanosensitive channel K16052 - - 0.0000000000000000000000000000003251 139.0
MMS1_k127_85296_44 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000002958 122.0
MMS1_k127_85296_45 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000006663 126.0
MMS1_k127_85296_46 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001367 127.0
MMS1_k127_85296_47 TatD related DNase K03424 - - 0.0000000000000000000000000001354 124.0
MMS1_k127_85296_48 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000001192 121.0
MMS1_k127_85296_49 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.00000000000000000002106 94.0
MMS1_k127_85296_5 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 616.0
MMS1_k127_85296_50 Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000009045 95.0
MMS1_k127_85296_51 ATP-AMP transphosphorylase K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000001775 93.0
MMS1_k127_85296_52 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000003793 97.0
MMS1_k127_85296_53 Acyl-CoA dehydrogenase, N-terminal domain K11729 GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000002662 86.0
MMS1_k127_85296_54 PFAM conserved - - - 0.0000000000000004924 89.0
MMS1_k127_85296_55 tRNA intron endonuclease K01170 - 4.6.1.16 0.000000000000001063 89.0
MMS1_k127_85296_56 Polysaccharide biosynthesis protein - - - 0.000000000000009519 87.0
MMS1_k127_85296_57 binds to the 23S rRNA K02921 - - 0.0000000000001128 73.0
MMS1_k127_85296_58 - - - - 0.0000000000003665 72.0
MMS1_k127_85296_59 Transcriptional regulator K07722 - - 0.0000000000005588 74.0
MMS1_k127_85296_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 592.0
MMS1_k127_85296_60 NUDIX domain - - - 0.000000000001993 73.0
MMS1_k127_85296_61 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000444 68.0
MMS1_k127_85296_62 Belongs to the eukaryotic ribosomal protein eL34 family K02915 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000006677 70.0
MMS1_k127_85296_63 Belongs to the UPF0147 family K09721 - - 0.000000000009105 68.0
MMS1_k127_85296_64 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000001469 74.0
MMS1_k127_85296_65 Oligosaccharyl transferase, STT3 subunit K07151 - 2.4.99.18 0.00000000001816 78.0
MMS1_k127_85296_67 Domain of unknown function (DUF929) - - - 0.00000000004779 75.0
MMS1_k127_85296_68 C-terminal AAA-associated domain K02049 - - 0.00000000006132 69.0
MMS1_k127_85296_69 binds to the 23S rRNA K02929 - - 0.000000001023 64.0
MMS1_k127_85296_7 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 548.0
MMS1_k127_85296_70 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000002371 60.0
MMS1_k127_85296_71 - - - - 0.00000004005 59.0
MMS1_k127_85296_72 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000606 50.0
MMS1_k127_85296_73 PFAM PRC-barrel domain - - - 0.00001929 51.0
MMS1_k127_85296_74 Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP K03537 GO:0000172,GO:0000294,GO:0000447,GO:0000460,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016074,GO:0018065,GO:0018193,GO:0018205,GO:0019222,GO:0019439,GO:0019538,GO:0022613,GO:0030490,GO:0030677,GO:0030681,GO:0031070,GO:0031974,GO:0031981,GO:0032991,GO:0033967,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034963,GO:0034965,GO:0036211,GO:0042254,GO:0042274,GO:0043144,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0051604,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901575,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0002654 48.0
MMS1_k127_85296_75 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00027 48.0
MMS1_k127_85296_8 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 551.0
MMS1_k127_85296_9 DNA polymerase K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 507.0
MMS1_k127_988529_0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00169,K00174 - 1.2.7.1,1.2.7.11,1.2.7.3 3.579e-254 797.0
MMS1_k127_988529_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 516.0
MMS1_k127_988529_10 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000008269 234.0
MMS1_k127_988529_11 DNA methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000001362 196.0
MMS1_k127_988529_12 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001041 182.0
MMS1_k127_988529_13 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.00000000000000000000000000000000000000000166 167.0
MMS1_k127_988529_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000009126 161.0
MMS1_k127_988529_15 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000009883 156.0
MMS1_k127_988529_16 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000001199 152.0
MMS1_k127_988529_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000002744 150.0
MMS1_k127_988529_18 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.00000000000000000000000000000000000004621 156.0
MMS1_k127_988529_19 Ndr family - - - 0.0000000000000000000000000000000006023 143.0
MMS1_k127_988529_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 481.0
MMS1_k127_988529_20 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000006173 133.0
MMS1_k127_988529_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001325 130.0
MMS1_k127_988529_22 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000005435 124.0
MMS1_k127_988529_23 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000001389 134.0
MMS1_k127_988529_24 TaqI restriction endonuclease - - - 0.000000000000000000000759 104.0
MMS1_k127_988529_25 Putative RNA methylase family UPF0020 - - - 0.000000000000000000006338 106.0
MMS1_k127_988529_26 endonuclease activity - - - 0.000000000000000005331 91.0
MMS1_k127_988529_27 Oligosaccharyl transferase, STT3 subunit K07151 - 2.4.99.18 0.00000000000005867 86.0
MMS1_k127_988529_28 PFAM EamA-like transporter family - - - 0.000000000005232 70.0
MMS1_k127_988529_29 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.0000000194 59.0
MMS1_k127_988529_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 400.0
MMS1_k127_988529_30 IMP dehydrogenase activity - - - 0.00000006915 55.0
MMS1_k127_988529_31 EamA-like transporter family - - - 0.0000005607 57.0
MMS1_k127_988529_32 PFAM Biotin lipoate A B protein ligase - - - 0.0001146 49.0
MMS1_k127_988529_33 Transcriptional regulator - - - 0.0003748 51.0
MMS1_k127_988529_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 404.0
MMS1_k127_988529_5 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 368.0
MMS1_k127_988529_6 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 329.0
MMS1_k127_988529_7 Glycosyl transferase family 21 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 301.0
MMS1_k127_988529_8 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002295 276.0
MMS1_k127_988529_9 alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000009646 277.0