Overview

ID MAG02747
Name MMS2_bin.56
Sample SMP0065
Taxonomy
Kingdom Bacteria
Phylum Margulisbacteria
Class WOR-1
Order O2-12-FULL-45-9
Family O2-12-FULL-45-9
Genus
Species
Assembly information
Completeness (%) 74.56
Contamination (%) 1.79
GC content (%) 50.0
N50 (bp) 2,318
Genome size (bp) 1,015,211

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1127

Gene name Description KEGG GOs EC E-value Score Sequence
MMS2_k127_1000647_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000584 253.0
MMS2_k127_1000647_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000001291 80.0
MMS2_k127_1006959_0 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000008613 130.0
MMS2_k127_1006959_1 slime layer polysaccharide biosynthetic process K16710 - - 0.00000000000000000000008262 104.0
MMS2_k127_1013353_0 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000007426 241.0
MMS2_k127_1013353_1 gas vesicle protein - - - 0.000001416 52.0
MMS2_k127_1013353_2 YtxH-like protein - - - 0.0001063 47.0
MMS2_k127_1024548_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000443 138.0
MMS2_k127_1024548_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000004198 89.0
MMS2_k127_1024548_2 CBS domain - - - 0.00000000000001023 79.0
MMS2_k127_1050320_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000008651 218.0
MMS2_k127_1050320_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000002595 92.0
MMS2_k127_1050320_2 ErfK YbiS YcfS YnhG family protein - - - 0.0004438 47.0
MMS2_k127_1052596_0 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000000000002934 135.0
MMS2_k127_1052596_1 Flagellar biosynthetic protein FliQ K02420 - - 0.000000000000000000002821 97.0
MMS2_k127_1052596_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000003966 71.0
MMS2_k127_1060415_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 578.0
MMS2_k127_1060415_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 367.0
MMS2_k127_1060415_2 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 297.0
MMS2_k127_1060415_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000007955 133.0
MMS2_k127_1060415_4 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000009751 73.0
MMS2_k127_1060415_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000006157 55.0
MMS2_k127_1061058_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 488.0
MMS2_k127_1066848_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.326e-253 793.0
MMS2_k127_1066848_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000006297 181.0
MMS2_k127_1070525_0 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000006634 190.0
MMS2_k127_107298_0 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000277 203.0
MMS2_k127_107298_1 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000003501 198.0
MMS2_k127_107298_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000003226 135.0
MMS2_k127_107298_3 Binds the 23S rRNA K02909 - - 0.00000000000000000000000115 105.0
MMS2_k127_107912_0 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000318 148.0
MMS2_k127_107912_1 PFAM Glycosyl transferase family 2 - - - 0.00001893 50.0
MMS2_k127_1099654_0 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000002915 182.0
MMS2_k127_1099654_1 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000004397 141.0
MMS2_k127_1099654_2 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000292 51.0
MMS2_k127_110131_0 Conserved protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001256 264.0
MMS2_k127_110131_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000009582 115.0
MMS2_k127_1109617_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 526.0
MMS2_k127_1109617_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 422.0
MMS2_k127_111278_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 321.0
MMS2_k127_111278_1 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000003408 194.0
MMS2_k127_1116938_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 351.0
MMS2_k127_1116938_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000635 55.0
MMS2_k127_112137_0 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000416 237.0
MMS2_k127_1144437_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.187e-290 907.0
MMS2_k127_1144437_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000005041 153.0
MMS2_k127_1160671_0 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 241.0
MMS2_k127_1160671_1 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000005572 109.0
MMS2_k127_1160671_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000001988 108.0
MMS2_k127_1161252_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 462.0
MMS2_k127_1161252_1 Belongs to the SEDS family K05837 - - 0.0008134 46.0
MMS2_k127_1172693_0 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K15256 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000009596 107.0
MMS2_k127_1172693_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.00006612 46.0
MMS2_k127_1185632_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000001872 241.0
MMS2_k127_1192004_0 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 372.0
MMS2_k127_1192004_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000126 282.0
MMS2_k127_124122_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000001347 202.0
MMS2_k127_124122_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000008126 100.0
MMS2_k127_124122_2 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.0000000003311 63.0
MMS2_k127_124186_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.00000000000000000000000000000000000000000000000000000000001136 214.0
MMS2_k127_124186_1 - - - - 0.000001199 61.0
MMS2_k127_127096_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000002788 164.0
MMS2_k127_127096_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000004978 156.0
MMS2_k127_127096_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000002329 121.0
MMS2_k127_1276710_0 ompA family - - - 0.00000000001161 78.0
MMS2_k127_127702_0 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 411.0
MMS2_k127_127702_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001017 278.0
MMS2_k127_1285812_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 300.0
MMS2_k127_1291431_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 387.0
MMS2_k127_1291431_1 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
MMS2_k127_1291431_2 Binds directly to 16S ribosomal RNA K02968 - - 0.000006464 51.0
MMS2_k127_1294556_0 PFAM Uncharacterised protein family (UPF0182) K09118 - - 3.195e-251 794.0
MMS2_k127_1294556_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000001044 235.0
MMS2_k127_1295332_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 388.0
MMS2_k127_129638_0 Methyltransferase type 11 - - - 0.0000006279 63.0
MMS2_k127_1310363_0 PFAM Fibronectin, type III domain - - - 0.000000000000000001148 102.0
MMS2_k127_1336325_0 protein involved in outer membrane biogenesis K07289 - - 0.000000000000004828 88.0
MMS2_k127_1343470_0 nucleotide-excision repair K03702,K08999 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 3.934e-261 819.0
MMS2_k127_1343470_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 361.0
MMS2_k127_1343470_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000006974 167.0
MMS2_k127_1343470_3 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) - - - 0.0000000000000000000000000000005543 130.0
MMS2_k127_1343470_4 ligase activity - - - 0.0000000000005261 77.0
MMS2_k127_1343960_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000001369 176.0
MMS2_k127_1343960_1 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000004346 71.0
MMS2_k127_1345581_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000006045 246.0
MMS2_k127_1345581_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000001204 164.0
MMS2_k127_1345581_2 Divergent PAP2 family K09775 - - 0.00000000000000000000000000000000006703 138.0
MMS2_k127_1363399_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000004092 199.0
MMS2_k127_1363399_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.00000000000000000000001385 109.0
MMS2_k127_1371707_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.916e-246 777.0
MMS2_k127_1371707_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 353.0
MMS2_k127_1371707_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000002397 63.0
MMS2_k127_1371707_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000001131 57.0
MMS2_k127_1377909_0 TIGRFAM pseudaminic acid synthase K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 388.0
MMS2_k127_1377909_1 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000009758 81.0
MMS2_k127_139385_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 396.0
MMS2_k127_139385_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 362.0
MMS2_k127_139385_2 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000001146 227.0
MMS2_k127_139385_3 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000009915 193.0
MMS2_k127_141661_0 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002531 271.0
MMS2_k127_141661_1 TPR repeat - - - 0.000000000003225 80.0
MMS2_k127_141661_2 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000003269 53.0
MMS2_k127_141661_3 peptidyl-tyrosine sulfation - - - 0.0003543 54.0
MMS2_k127_1438669_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004391 201.0
MMS2_k127_1438669_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000007551 128.0
MMS2_k127_1438669_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000004841 118.0
MMS2_k127_1438669_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000003558 116.0
MMS2_k127_1481191_0 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000002958 259.0
MMS2_k127_1481191_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000002303 227.0
MMS2_k127_1481191_2 pfam rok K00845 - 2.7.1.2 0.000000000001523 69.0
MMS2_k127_1494312_0 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000486 124.0
MMS2_k127_149652_0 Type II IV secretion system protein K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 476.0
MMS2_k127_149652_1 Type II secretion system (T2SS), protein F K02653,K12278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 319.0
MMS2_k127_149652_2 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000005627 69.0
MMS2_k127_15053_0 recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000046 271.0
MMS2_k127_15053_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000004125 228.0
MMS2_k127_15053_2 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000006773 184.0
MMS2_k127_1516163_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 559.0
MMS2_k127_1516163_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000001106 61.0
MMS2_k127_1526510_0 TIGRFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001813 277.0
MMS2_k127_1526510_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000002022 72.0
MMS2_k127_1527064_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.399e-198 629.0
MMS2_k127_1527064_1 Glutamate formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001151 272.0
MMS2_k127_1527064_2 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000001584 138.0
MMS2_k127_1550130_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 351.0
MMS2_k127_1550130_1 TonB-dependent Receptor Plug K02014,K16089 - - 0.000000000000000000000000000000000000000000000000006757 202.0
MMS2_k127_1550130_2 Protein of unknown function (DUF2905) - - - 0.000000000000000162 81.0
MMS2_k127_1550130_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000002926 64.0
MMS2_k127_1565389_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000001861 189.0
MMS2_k127_1565389_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000001482 129.0
MMS2_k127_1565389_2 JAB/MPN domain K21140 - 3.13.1.6 0.00000008074 62.0
MMS2_k127_1583133_0 Pfam Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000005323 79.0
MMS2_k127_1583133_1 - - - - 0.0005751 51.0
MMS2_k127_160329_0 Belongs to the ClpA ClpB family K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 473.0
MMS2_k127_1610221_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 439.0
MMS2_k127_1610221_1 PFAM Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 321.0
MMS2_k127_1610221_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000001027 194.0
MMS2_k127_1618709_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000004566 248.0
MMS2_k127_1618709_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000006823 213.0
MMS2_k127_1622861_0 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.00000000000000000000000000000000000000000000000000000000000001073 224.0
MMS2_k127_1622861_1 Flagellar basal body rod FlgEFG protein C-terminal K02392 - - 0.00000000000000000000000000000404 128.0
MMS2_k127_1622861_2 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.000000000000000000004668 96.0
MMS2_k127_1635203_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.952e-268 843.0
MMS2_k127_1635203_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 349.0
MMS2_k127_1639874_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
MMS2_k127_1645822_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000003564 246.0
MMS2_k127_1645822_1 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000006155 73.0
MMS2_k127_1645822_2 transmembrane transport - - - 0.000000000000781 77.0
MMS2_k127_1645998_0 Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004351 265.0
MMS2_k127_1657021_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000001427 265.0
MMS2_k127_1698649_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 312.0
MMS2_k127_1698649_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000006799 250.0
MMS2_k127_1698649_2 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000004321 170.0
MMS2_k127_1698649_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000007609 63.0
MMS2_k127_1709956_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000002286 163.0
MMS2_k127_1715984_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003857 271.0
MMS2_k127_1715984_1 S-layer homology domain - - - 0.000000000001058 79.0
MMS2_k127_1716179_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 425.0
MMS2_k127_1716179_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000007755 168.0
MMS2_k127_1716179_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03087 - - 0.0000000000000000000000000000003976 137.0
MMS2_k127_1716179_3 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000006884 119.0
MMS2_k127_1717134_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001132 263.0
MMS2_k127_1717134_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001195 233.0
MMS2_k127_175068_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000004981 221.0
MMS2_k127_175068_1 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000001258 194.0
MMS2_k127_175068_2 Bifunctional protein - - - 0.0000000000000000000000000000000000000000000001785 174.0
MMS2_k127_175331_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000002613 203.0
MMS2_k127_175331_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000121 171.0
MMS2_k127_175331_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000002395 163.0
MMS2_k127_1761818_0 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000004382 202.0
MMS2_k127_1761818_1 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - 0.000000000000000000001608 96.0
MMS2_k127_1761818_2 flagellar motor switch protein K02416 - - 0.000004655 54.0
MMS2_k127_176521_0 chelatase, subunit chli K06400,K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 550.0
MMS2_k127_1771129_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 329.0
MMS2_k127_1771129_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000581 270.0
MMS2_k127_1771129_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000002277 179.0
MMS2_k127_1780621_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002345 239.0
MMS2_k127_1780621_1 4Fe-4S single cluster domain - - - 0.000000000000000005537 86.0
MMS2_k127_1788218_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007793 258.0
MMS2_k127_1788218_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001272 206.0
MMS2_k127_1788218_2 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000001914 96.0
MMS2_k127_1788218_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000002415 60.0
MMS2_k127_1806775_0 Prokaryotic N-terminal methylation motif K02457 - - 0.0000004322 59.0
MMS2_k127_1823095_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 316.0
MMS2_k127_1823095_1 Phospholipid methyltransferase - - - 0.000000003912 64.0
MMS2_k127_1857153_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000006296 246.0
MMS2_k127_1857153_1 PolyA polymerase K00974 - 2.7.7.72 0.0000000000000000000000000000000000002675 145.0
MMS2_k127_1857153_2 Cell Wall K01448 - 3.5.1.28 0.0000000000000000000000000000000000639 146.0
MMS2_k127_1857153_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000001026 50.0
MMS2_k127_187623_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001333 288.0
MMS2_k127_187927_0 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009591 259.0
MMS2_k127_1881236_0 Thymidylate synthase complementing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 449.0
MMS2_k127_1881236_1 Polymer-forming cytoskeletal - - - 0.00001395 55.0
MMS2_k127_1885155_0 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
MMS2_k127_1885155_1 Acetyltransferase (GNAT) domain - - - 0.0000000000001018 74.0
MMS2_k127_1893903_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 610.0
MMS2_k127_1893903_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 313.0
MMS2_k127_1893903_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000001532 263.0
MMS2_k127_1893903_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000408 189.0
MMS2_k127_1893903_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000001088 99.0
MMS2_k127_1893903_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000571 61.0
MMS2_k127_1893903_6 PFAM Outer membrane chaperone Skp (OmpH) K06142 - - 0.0005638 48.0
MMS2_k127_1920721_0 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000009185 148.0
MMS2_k127_1935274_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 412.0
MMS2_k127_1935274_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000005045 187.0
MMS2_k127_193741_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 421.0
MMS2_k127_1941094_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000001541 160.0
MMS2_k127_1941094_1 phosphate transporter K16331 - - 0.0000000000000000000000000000000001024 141.0
MMS2_k127_1941094_2 Uroporphyrinogen-III synthase K13542 - 2.1.1.107,4.2.1.75 0.0000000000000128 76.0
MMS2_k127_1985431_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001211 254.0
MMS2_k127_1985431_1 ATPases associated with a variety of cellular activities K02003,K02004 - - 0.0000000000000000004721 87.0
MMS2_k127_1995305_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008076 259.0
MMS2_k127_1998184_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000001858 230.0
MMS2_k127_1998184_1 Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position K01271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000009147 224.0
MMS2_k127_1998184_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000009464 187.0
MMS2_k127_1998184_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000003667 59.0
MMS2_k127_2015342_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000569 148.0
MMS2_k127_2084400_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000323 275.0
MMS2_k127_2084400_1 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000005455 182.0
MMS2_k127_2084400_2 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.000000000000000000000000000000000000000000007539 168.0
MMS2_k127_2087095_0 Flavin reductase-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006294 224.0
MMS2_k127_2087095_1 23S rRNA-intervening sequence protein - - - 0.0000000000000000000004137 98.0
MMS2_k127_2093977_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 359.0
MMS2_k127_2093977_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.00000000000000000000000000000000000005991 143.0
MMS2_k127_2093977_2 Methionine biosynthesis protein MetW - - - 0.0000000000004013 72.0
MMS2_k127_2097962_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 418.0
MMS2_k127_2097962_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000007308 233.0
MMS2_k127_2104057_0 magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 301.0
MMS2_k127_2104057_1 Pfam Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000041 67.0
MMS2_k127_21086_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 481.0
MMS2_k127_212513_0 FAD dependent oxidoreductase K00109,K00273,K15736 - 1.1.99.2,1.4.3.3 0.00000000000000000000000000000000000000000000000007027 186.0
MMS2_k127_212513_1 Protein of unknown function (DUF1622) - - - 0.00000000000000004885 85.0
MMS2_k127_212513_2 Belongs to the CarB family K01955 - 6.3.5.5 0.00001359 48.0
MMS2_k127_2127297_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
MMS2_k127_2127297_1 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000003742 231.0
MMS2_k127_2127297_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000001849 126.0
MMS2_k127_2127297_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000286 101.0
MMS2_k127_2152704_0 Na Pi-cotransporter II-like protein K03324 - - 0.000000000000000000000000000000000000000000000021 178.0
MMS2_k127_2152704_1 - - - - 0.0000000495 62.0
MMS2_k127_216718_0 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000001424 265.0
MMS2_k127_216718_1 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000001645 66.0
MMS2_k127_2175721_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.241e-316 990.0
MMS2_k127_2175721_1 - - - - 0.0000000000002196 71.0
MMS2_k127_2202127_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 322.0
MMS2_k127_22045_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 424.0
MMS2_k127_22045_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000002809 145.0
MMS2_k127_22045_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0001546 46.0
MMS2_k127_2209512_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 366.0
MMS2_k127_2209512_1 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000002921 138.0
MMS2_k127_2215620_0 protein secretion K01077,K01119,K02664,K08693 - 3.1.3.1,3.1.3.5,3.1.3.6,3.1.4.16 0.00000000000000000000000004161 125.0
MMS2_k127_2215620_1 Peptidase C25 - - - 0.000000000002335 76.0
MMS2_k127_222735_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000001732 226.0
MMS2_k127_222735_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000002069 107.0
MMS2_k127_222735_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000002074 107.0
MMS2_k127_2243413_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000001862 200.0
MMS2_k127_2243413_1 Exopolysaccharide biosynthesis protein YbjH - - - 0.0001518 52.0
MMS2_k127_2248248_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 325.0
MMS2_k127_2248248_1 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000002184 208.0
MMS2_k127_2265902_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000002408 222.0
MMS2_k127_2265902_1 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000007512 192.0
MMS2_k127_2267473_0 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 302.0
MMS2_k127_2267473_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000002197 68.0
MMS2_k127_2284878_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000002519 202.0
MMS2_k127_2284878_1 DHH family K07462 - - 0.000000000000000000000000000000000000000000001189 171.0
MMS2_k127_2284878_2 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000000229 138.0
MMS2_k127_2284878_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000003683 135.0
MMS2_k127_2304217_0 HYR domain - - - 0.000000000003841 79.0
MMS2_k127_2309502_0 breast cancer carboxy-terminal domain K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 469.0
MMS2_k127_2321610_0 PFAM outer membrane efflux protein - - - 0.000005354 55.0
MMS2_k127_2327711_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.057e-194 616.0
MMS2_k127_2327711_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 403.0
MMS2_k127_2327711_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000119 114.0
MMS2_k127_2328273_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 378.0
MMS2_k127_2328273_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 350.0
MMS2_k127_2328273_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000001773 145.0
MMS2_k127_2331279_0 PFAM Pyridoxal-dependent decarboxylase K01580 GO:0003674,GO:0003824,GO:0004068,GO:0016829,GO:0016830,GO:0016831 4.1.1.15 0.000000000000000000000000000000000000000000000000000000000000005154 230.0
MMS2_k127_2343655_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 7.685e-236 751.0
MMS2_k127_2343655_1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.0001073 46.0
MMS2_k127_2373328_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000003762 136.0
MMS2_k127_2373328_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000004511 64.0
MMS2_k127_2383088_0 MacB-like periplasmic core domain K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 470.0
MMS2_k127_2383088_1 TIGRFAM efflux transporter, RND family, MFP subunit K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003394 252.0
MMS2_k127_2383088_2 FusA NodT family protein - - - 0.000000000000000000002459 102.0
MMS2_k127_2391982_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 420.0
MMS2_k127_2391982_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000005488 220.0
MMS2_k127_2414525_0 Protein of unknown function (DUF559) - - - 0.000000000000003598 78.0
MMS2_k127_2414525_1 Belongs to the peptidase S8 family - - - 0.0000000001049 75.0
MMS2_k127_2416549_0 - - - - 0.000000000000000000007447 105.0
MMS2_k127_2416549_1 Glycosyltransferase like family K07011 - - 0.000000000000000006496 89.0
MMS2_k127_2421346_0 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000008776 248.0
MMS2_k127_2421346_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000005682 48.0
MMS2_k127_2423407_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 309.0
MMS2_k127_2423407_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000005425 129.0
MMS2_k127_2432236_0 TIGRFAM Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 326.0
MMS2_k127_2434394_0 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001114 257.0
MMS2_k127_2437976_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 9.273e-199 627.0
MMS2_k127_2437976_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 529.0
MMS2_k127_2437976_2 ABC transporter K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 281.0
MMS2_k127_2437976_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000008621 216.0
MMS2_k127_2437976_4 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000001474 201.0
MMS2_k127_2437976_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000679 108.0
MMS2_k127_2437976_6 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000001564 84.0
MMS2_k127_24577_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 302.0
MMS2_k127_24577_1 - - - - 0.000000002317 66.0
MMS2_k127_2463447_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 410.0
MMS2_k127_246403_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 342.0
MMS2_k127_246403_1 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000007457 194.0
MMS2_k127_2501710_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000001956 222.0
MMS2_k127_2506010_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 385.0
MMS2_k127_2506010_1 ABC transporter, ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 284.0
MMS2_k127_2506010_2 Permease, YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002129 277.0
MMS2_k127_2506010_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003896 257.0
MMS2_k127_2506010_4 Protein of unknown function (DUF3084) - - - 0.00000000000000000000000000000000008493 145.0
MMS2_k127_2506010_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - - - 0.0000000002284 66.0
MMS2_k127_2533620_0 Integral membrane sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000003327 197.0
MMS2_k127_2533620_1 Transporter, CPA2 family - - - 0.000000000000000000000000000000000000000000000000004324 191.0
MMS2_k127_2533620_2 branched-chain-amino-acid transaminase activity K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000001062 173.0
MMS2_k127_2533620_3 PAS domain K07315 - 3.1.3.3 0.0000000000005641 76.0
MMS2_k127_2545898_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 332.0
MMS2_k127_2545898_1 rRNA binding K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002357 141.0
MMS2_k127_2550957_0 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 323.0
MMS2_k127_2557695_0 PFAM Surface antigen variable number repeat K07277 - - 0.000000000000000000000000005333 116.0
MMS2_k127_2580095_0 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000002172 111.0
MMS2_k127_2580095_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000003579 104.0
MMS2_k127_2587170_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.715e-194 619.0
MMS2_k127_2587170_1 TIGRFAM MazG family protein K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.000000000000000000000004461 105.0
MMS2_k127_2597719_0 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 462.0
MMS2_k127_2597719_1 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 413.0
MMS2_k127_2597719_2 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 296.0
MMS2_k127_2597719_3 Glycosyltransferase like family 2 K07011,K13659 - 2.4.1.264 0.00000000000000000000000000000000000000000000000000000000000000000003638 246.0
MMS2_k127_2597719_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008830,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.1.3.13 0.0000000000000000000000000000000000000000000000000000001192 199.0
MMS2_k127_2597719_5 Glycosyltransferase like family 2 K03606,K07011 - - 0.0000000000000000000000000000000000000000000000000000009526 208.0
MMS2_k127_2597719_6 NAD-dependent epimerase dehydratase K19180 - 1.1.1.339 0.0000000000000000000000000000000000000000004393 168.0
MMS2_k127_2610530_0 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000009619 95.0
MMS2_k127_2610530_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000003855 59.0
MMS2_k127_2610530_2 NQR2, RnfD, RnfE family - - - 0.0000006749 59.0
MMS2_k127_2610530_3 - - - - 0.000002366 53.0
MMS2_k127_2617869_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
MMS2_k127_2617869_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000002379 200.0
MMS2_k127_2617869_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000007414 107.0
MMS2_k127_2617869_3 negative regulation of DNA recombination - - - 0.000000005624 64.0
MMS2_k127_2631216_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 509.0
MMS2_k127_2631216_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000231 85.0
MMS2_k127_2632491_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 519.0
MMS2_k127_2632491_1 Desulfoferrodoxin, N-terminal domain K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000001618 205.0
MMS2_k127_2632491_2 Ferritin-like domain K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000006492 169.0
MMS2_k127_2632491_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000001676 153.0
MMS2_k127_2632491_4 Rubredoxin - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000002319 97.0
MMS2_k127_2633798_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 505.0
MMS2_k127_2633798_1 Bacterial transferase hexapeptide (three repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000001941 215.0
MMS2_k127_2633798_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000002494 102.0
MMS2_k127_2640148_0 Cellulase (glycosyl hydrolase family 5) - - - 0.00000000000000000000000000000000000000000001489 176.0
MMS2_k127_2640148_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000001768 93.0
MMS2_k127_2640148_2 Sodium/hydrogen exchanger family - - - 0.0000000000000001724 83.0
MMS2_k127_264133_0 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000007152 248.0
MMS2_k127_264133_1 Tetratricopeptide repeat - - - 0.0000002177 61.0
MMS2_k127_2655723_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005431 273.0
MMS2_k127_2655723_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000001721 201.0
MMS2_k127_2657594_0 PFAM type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000001561 163.0
MMS2_k127_2657594_1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.0000000005149 61.0
MMS2_k127_268463_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005748 260.0
MMS2_k127_2687371_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000002139 222.0
MMS2_k127_2687371_1 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000009298 113.0
MMS2_k127_2695588_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 592.0
MMS2_k127_2695588_1 PFAM NUDIX hydrolase - - - 0.00000003987 63.0
MMS2_k127_272493_0 Nucleotidyl transferase K11528 - 2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000002742 257.0
MMS2_k127_272493_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000519 203.0
MMS2_k127_272493_2 SMART Metal-dependent phosphohydrolase, HD region K00969 - 2.7.7.18 0.0000006677 52.0
MMS2_k127_2753017_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 561.0
MMS2_k127_2759870_0 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000000000000000000000000139 204.0
MMS2_k127_2759870_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000005054 97.0
MMS2_k127_2778174_0 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 2.154e-211 665.0
MMS2_k127_2783509_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000001448 226.0
MMS2_k127_2783509_1 Glycosyl transferase family 2 K09931 - - 0.00000000000000000000000000000000000000000000003105 178.0
MMS2_k127_2783509_2 PFAM Rubrerythrin - - - 0.000000000000000001259 85.0
MMS2_k127_278427_0 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 310.0
MMS2_k127_278427_1 PFAM Ribulose-phosphate 3-epimerase K01783,K17195 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000001249 203.0
MMS2_k127_278427_2 myo-inosose-2 dehydratase activity K21909 - 5.1.3.38 0.00000000000000000000000000006993 118.0
MMS2_k127_2805840_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
MMS2_k127_2805840_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 290.0
MMS2_k127_2812712_0 PFAM Methyltransferase K15256 - - 0.000000000000000000000000000000000000000000000000000000007908 205.0
MMS2_k127_2812712_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000002493 171.0
MMS2_k127_2814824_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 371.0
MMS2_k127_2814824_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.000000000000000000006221 106.0
MMS2_k127_284042_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 305.0
MMS2_k127_284042_1 radical SAM domain protein K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000115 253.0
MMS2_k127_284828_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
MMS2_k127_284828_1 - - - - 0.000009705 49.0
MMS2_k127_284828_2 Prokaryotic N-terminal methylation motif K10924 - - 0.00004021 52.0
MMS2_k127_2850561_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 2.346e-300 931.0
MMS2_k127_2850561_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 307.0
MMS2_k127_2850561_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000002301 174.0
MMS2_k127_2850561_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000003323 169.0
MMS2_k127_2853670_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 317.0
MMS2_k127_2858945_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 375.0
MMS2_k127_2858945_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001378 265.0
MMS2_k127_2858945_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000002877 129.0
MMS2_k127_2858945_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000003658 85.0
MMS2_k127_2858945_4 PASTA K08884 - 2.7.11.1 0.000001754 58.0
MMS2_k127_2858945_5 Phosphate-selective porin O and P - - - 0.0003259 51.0
MMS2_k127_2874837_0 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000001218 108.0
MMS2_k127_2886552_0 COG1209 dTDP-glucose pyrophosphorylase K00973 - 2.7.7.24 0.00000000000000000000001199 109.0
MMS2_k127_2886552_1 glycosyl transferase group 1 - - - 0.000000000000000000001133 101.0
MMS2_k127_2886552_2 Glycosyl transferases group 1 - - - 0.0004509 46.0
MMS2_k127_289727_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 364.0
MMS2_k127_289727_1 TIGRFAM potassium uptake protein, TrkH family K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 343.0
MMS2_k127_289727_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000127 117.0
MMS2_k127_2897672_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 479.0
MMS2_k127_2897672_1 Aspartate decarboxylase K01579 - 4.1.1.11 0.0000000114 57.0
MMS2_k127_2912335_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003078 273.0
MMS2_k127_2912335_1 long-chain fatty acid transport protein - - - 0.00000163 60.0
MMS2_k127_2912335_2 S-layer homology domain - - - 0.00003553 56.0
MMS2_k127_2918428_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000376 215.0
MMS2_k127_2918428_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000004762 176.0
MMS2_k127_2918428_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000003724 111.0
MMS2_k127_2918428_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000003298 109.0
MMS2_k127_2918428_4 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.0000000000000000007768 91.0
MMS2_k127_2920275_0 Histidine kinase - - - 0.00000000000000000000000003779 123.0
MMS2_k127_2920275_1 Putative small multi-drug export protein - - - 0.000000000000000008308 87.0
MMS2_k127_2920275_2 histidine kinase HAMP region domain protein - - - 0.0000000000000006988 90.0
MMS2_k127_295635_0 Carbamoyl-phosphate synthetase large chain oligomerisation K01955 - 6.3.5.5 0.0 1076.0
MMS2_k127_2982745_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000009076 213.0
MMS2_k127_2982745_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000004314 195.0
MMS2_k127_2988811_0 PhoQ Sensor - - - 0.0000000000000000000001044 109.0
MMS2_k127_2991998_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000001119 178.0
MMS2_k127_2991998_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000009863 131.0
MMS2_k127_3011346_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 434.0
MMS2_k127_3033282_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 561.0
MMS2_k127_3033282_1 metallophosphoesterase K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 302.0
MMS2_k127_3033282_2 chitin catabolic process K01183,K03933,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.14,3.2.1.17 0.000000000000000000000000000000000000000000000000000001286 211.0
MMS2_k127_3033282_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000003471 181.0
MMS2_k127_3033282_4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000002008 64.0
MMS2_k127_305358_0 In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 543.0
MMS2_k127_305358_1 biotin synthase activity K01012,K04653 - 2.8.1.6 0.00000000000000000000000000000000000006023 147.0
MMS2_k127_305358_2 FAD dependent oxidoreductase K07007 - - 0.0000000000000000000000000000000001959 136.0
MMS2_k127_3054997_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 574.0
MMS2_k127_3054997_1 Glycosyltransferase like family 2 - - - 0.00000003652 55.0
MMS2_k127_3061499_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 2.352e-205 654.0
MMS2_k127_3062224_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000001762 254.0
MMS2_k127_3062972_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000001447 156.0
MMS2_k127_3062972_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000003815 150.0
MMS2_k127_3062972_2 Acyl-CoA thioesterase K07107 - - 0.00000000000000000000000001857 113.0
MMS2_k127_3069427_0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000006957 249.0
MMS2_k127_3069427_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000006622 212.0
MMS2_k127_3069427_2 KR domain - - - 0.0000000000000000000000000000001562 128.0
MMS2_k127_3114487_0 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.000000000000000000000000000000000000000000000000000000001329 213.0
MMS2_k127_3114487_1 Oxidoreductase domain protein K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000002533 186.0
MMS2_k127_3124298_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 5e-324 1000.0
MMS2_k127_3124298_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000002692 258.0
MMS2_k127_3124298_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000001206 209.0
MMS2_k127_3124298_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000001444 198.0
MMS2_k127_3141351_0 Domain of unknown function (DUF2172) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 452.0
MMS2_k127_3141351_1 Cytidylyltransferase K07257 - - 0.000000000000000000000000000000000000000000000000000000000000006862 222.0
MMS2_k127_3144193_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 4.223e-225 708.0
MMS2_k127_3144193_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001437 262.0
MMS2_k127_3144193_2 mRNA catabolic process - - - 0.000000000000000000000000000006272 123.0
MMS2_k127_3144193_3 transcriptional regulator, Rrf2 family - - - 0.0000000000000002096 83.0
MMS2_k127_3144193_4 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000001412 60.0
MMS2_k127_3147274_0 Purine nucleoside phosphorylase involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 302.0
MMS2_k127_3148928_0 transferase activity, transferring glycosyl groups K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000001525 232.0
MMS2_k127_3148928_1 4Fe-4S single cluster domain K06139 - - 0.000000000000000000000000005414 117.0
MMS2_k127_3148928_2 NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000001782 81.0
MMS2_k127_3187691_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 292.0
MMS2_k127_3187691_1 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000002367 256.0
MMS2_k127_3187691_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000003522 107.0
MMS2_k127_3187691_3 POTRA domain, FtsQ-type K03589 - - 0.000000005269 64.0
MMS2_k127_3190181_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 530.0
MMS2_k127_3190181_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 381.0
MMS2_k127_3190181_2 Catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 375.0
MMS2_k127_3190181_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000009364 241.0
MMS2_k127_3190181_4 - - - - 0.0000000000001811 72.0
MMS2_k127_3222075_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000007152 209.0
MMS2_k127_3222075_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000003498 198.0
MMS2_k127_3222075_2 VanW like protein K18346 - - 0.00000000000000000000000000271 117.0
MMS2_k127_3245800_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 7.984e-233 733.0
MMS2_k127_3245800_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
MMS2_k127_3245800_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000678 168.0
MMS2_k127_3245800_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000001578 115.0
MMS2_k127_3245800_4 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000004794 68.0
MMS2_k127_32600_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 464.0
MMS2_k127_32600_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000001691 242.0
MMS2_k127_3278694_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000004427 105.0
MMS2_k127_329403_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
MMS2_k127_329403_1 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000002823 110.0
MMS2_k127_3299799_0 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000005588 247.0
MMS2_k127_3299799_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000255 137.0
MMS2_k127_3301887_0 Hep Hag repeat protein - - - 0.00003114 56.0
MMS2_k127_3308629_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 434.0
MMS2_k127_3308629_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 305.0
MMS2_k127_3308629_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000001677 236.0
MMS2_k127_3319447_0 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 394.0
MMS2_k127_3347891_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 602.0
MMS2_k127_3347891_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 353.0
MMS2_k127_3347891_2 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 290.0
MMS2_k127_3347891_3 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.0000000000000000000000000000000000000000000000000000000000007991 221.0
MMS2_k127_3347891_4 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K07533 - 5.2.1.8 0.00000000000000000000000000000000002079 151.0
MMS2_k127_3352416_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000005188 104.0
MMS2_k127_3356032_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.000000000000000000000000000000000000000000000000000000000000001696 236.0
MMS2_k127_336025_0 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000006092 165.0
MMS2_k127_336025_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000001433 151.0
MMS2_k127_336025_2 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000002625 104.0
MMS2_k127_336025_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000004601 81.0
MMS2_k127_3365506_0 Psort location Cytoplasmic, score K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000007444 160.0
MMS2_k127_3365506_1 Nodulation protein S (NodS) - - - 0.00000000000244 76.0
MMS2_k127_3365506_2 lactoylglutathione lyase activity - - - 0.00000005064 62.0
MMS2_k127_3365506_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000001466 53.0
MMS2_k127_33686_0 PFAM Family of K09800 - - 0.0000000000000000000008215 111.0
MMS2_k127_3368867_0 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 316.0
MMS2_k127_3368867_1 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 313.0
MMS2_k127_3368867_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
MMS2_k127_3368867_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000002939 233.0
MMS2_k127_3368867_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000002098 171.0
MMS2_k127_3368867_5 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000002044 168.0
MMS2_k127_3368867_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000001277 97.0
MMS2_k127_3375662_0 signal peptide peptidase K04773 - - 0.0000000000000000000000001438 122.0
MMS2_k127_3381374_0 - - - - 0.00000000000000000000000000000000001061 144.0
MMS2_k127_3390657_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 298.0
MMS2_k127_3390657_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000003801 228.0
MMS2_k127_3392510_0 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000002263 138.0
MMS2_k127_3393371_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 344.0
MMS2_k127_3393371_1 Transposase - - - 0.00000000000000000000621 99.0
MMS2_k127_3393371_2 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000005539 52.0
MMS2_k127_3398943_0 Na+/Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 306.0
MMS2_k127_3398943_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000004109 212.0
MMS2_k127_3398943_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000116 106.0
MMS2_k127_3404961_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000001446 134.0
MMS2_k127_3404961_1 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000001319 135.0
MMS2_k127_3404961_2 single-stranded DNA binding K03111 - - 0.000000000000000000000000000000003213 132.0
MMS2_k127_3404961_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - 0.000000000000000000000005872 106.0
MMS2_k127_3404961_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000002567 87.0
MMS2_k127_3404961_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000003054 79.0
MMS2_k127_3404961_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000002525 68.0
MMS2_k127_341228_0 transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000000000003962 183.0
MMS2_k127_341228_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000001013 115.0
MMS2_k127_343985_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 401.0
MMS2_k127_343985_1 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000008442 98.0
MMS2_k127_3440081_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000004556 245.0
MMS2_k127_3440081_1 cephalosporin-C deacetylase activity - - - 0.000000000000000001974 96.0
MMS2_k127_3444519_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 294.0
MMS2_k127_3444519_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001275 286.0
MMS2_k127_3444519_2 NHL repeat - - - 0.0000000000000000000000000000000000000000001723 172.0
MMS2_k127_3445496_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 481.0
MMS2_k127_3446847_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1234.0
MMS2_k127_3446847_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000003093 128.0
MMS2_k127_3446847_2 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000004999 108.0
MMS2_k127_3451898_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 402.0
MMS2_k127_3451898_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000003579 278.0
MMS2_k127_3451898_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000001394 79.0
MMS2_k127_3451898_3 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000003197 75.0
MMS2_k127_3451898_4 Polymer-forming cytoskeletal - - - 0.0000001614 58.0
MMS2_k127_3473458_0 UDP-glucose 4-epimerase activity K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000007793 258.0
MMS2_k127_3473458_1 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.00000000000000251 80.0
MMS2_k127_3482878_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 291.0
MMS2_k127_3482878_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000001367 158.0
MMS2_k127_3482878_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000005097 53.0
MMS2_k127_3497532_0 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000003971 153.0
MMS2_k127_3497532_1 the major facilitator superfamily K03446 - - 0.0000000000000000000000000000000000006268 149.0
MMS2_k127_3500698_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 301.0
MMS2_k127_3500698_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000002004 132.0
MMS2_k127_3500698_2 PFAM Metal-dependent phosphohydrolase, HD K07037 - - 0.000000000000000000000000002339 120.0
MMS2_k127_3500698_3 Protein of unknown function (DUF3641) - - - 0.0000000000000000000004162 96.0
MMS2_k127_3500736_0 Glycosyl transferase K00702 - 2.4.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 528.0
MMS2_k127_3546753_0 - - - - 0.000000000000002163 86.0
MMS2_k127_3571959_0 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000004079 188.0
MMS2_k127_3571959_1 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.000000000000000000000000000000000000002431 148.0
MMS2_k127_3593242_0 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000001211 173.0
MMS2_k127_3593242_1 pentapeptide repeat protein - - - 0.000000000005922 72.0
MMS2_k127_3596093_0 AcrB/AcrD/AcrF family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 592.0
MMS2_k127_359659_0 ABC transporter K10112 - - 0.000000000000000000000000000000001961 134.0
MMS2_k127_359659_1 protein conserved in bacteria - - - 0.0000000000000000000002406 106.0
MMS2_k127_360149_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 492.0
MMS2_k127_360149_1 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000003562 113.0
MMS2_k127_361302_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000002276 168.0
MMS2_k127_361302_1 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K15256 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000005643 58.0
MMS2_k127_3624838_0 Tetratricopeptide repeat - - - 0.000000000000000000000008874 116.0
MMS2_k127_3624838_1 Protein of unknown function (DUF1282) - - - 0.000000000000000000007163 98.0
MMS2_k127_3624838_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000005114 58.0
MMS2_k127_3624838_3 long-chain fatty acid transporting porin activity K06076 - - 0.00007777 55.0
MMS2_k127_363302_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 351.0
MMS2_k127_3653375_0 methyltransferase activity - - - 0.00000006098 57.0
MMS2_k127_3653375_1 Histidine kinase - - - 0.0000003273 61.0
MMS2_k127_3663597_0 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000004469 252.0
MMS2_k127_3663597_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000119 206.0
MMS2_k127_3663597_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K16881 - 2.7.7.13,5.4.2.8 0.00000000000005288 72.0
MMS2_k127_3701841_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000003383 200.0
MMS2_k127_3701841_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000377 49.0
MMS2_k127_3714501_0 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000001295 165.0
MMS2_k127_3714501_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000005692 119.0
MMS2_k127_3714501_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02490 - - 0.000000000000006162 81.0
MMS2_k127_3732551_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000002618 220.0
MMS2_k127_3732551_1 O-Antigen ligase - - - 0.0001025 54.0
MMS2_k127_3737324_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001387 280.0
MMS2_k127_3737324_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000153 236.0
MMS2_k127_3744713_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 387.0
MMS2_k127_3744713_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000002585 126.0
MMS2_k127_3748479_0 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000006132 177.0
MMS2_k127_3748479_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000004285 131.0
MMS2_k127_3748479_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000001321 121.0
MMS2_k127_3748479_3 - - - - 0.0000000000006343 79.0
MMS2_k127_3748479_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000001697 61.0
MMS2_k127_376289_0 glycosyl transferase family 2 K00721,K20534 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 308.0
MMS2_k127_376289_1 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.0000000006782 63.0
MMS2_k127_3763098_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000149 192.0
MMS2_k127_3778679_0 PFAM 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 368.0
MMS2_k127_3778679_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000001383 110.0
MMS2_k127_3798749_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000006331 144.0
MMS2_k127_3798749_1 B12 binding domain - - - 0.000000000001774 77.0
MMS2_k127_3810244_0 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 329.0
MMS2_k127_3810244_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000003545 128.0
MMS2_k127_3810244_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000004367 48.0
MMS2_k127_3813254_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 464.0
MMS2_k127_3813254_1 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000001107 220.0
MMS2_k127_3813254_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000006973 184.0
MMS2_k127_3813254_3 transglycosylase K08309 - - 0.000000000000000000000000000000000002784 141.0
MMS2_k127_3830842_0 hydrolase family 65, central catalytic K10231 - 2.4.1.230 0.00000000000000000000000000000000000000000000006833 174.0
MMS2_k127_3830842_1 deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000007718 164.0
MMS2_k127_3830842_2 PFAM MscS Mechanosensitive ion channel K16052 - - 0.0000000000000000000007952 100.0
MMS2_k127_3859082_0 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000599 180.0
MMS2_k127_3859082_1 TIGRFAM cell envelope-related function transcriptional attenuator common domain - - - 0.00000000000000000000000000000000000000002828 160.0
MMS2_k127_3859082_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000466 105.0
MMS2_k127_3868380_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 550.0
MMS2_k127_3868380_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 475.0
MMS2_k127_3868380_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 445.0
MMS2_k127_3868380_3 PFAM Thiamine pyrophosphate K00170,K19071 - 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 410.0
MMS2_k127_3868380_4 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000001256 138.0
MMS2_k127_3868380_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000001413 125.0
MMS2_k127_3868380_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000002759 95.0
MMS2_k127_3871425_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 506.0
MMS2_k127_3871425_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000005858 203.0
MMS2_k127_3871425_2 Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - 0.0000000184 66.0
MMS2_k127_3890741_0 PAS domain K07710 - 2.7.13.3 0.000000000000000000000000000000000000000007978 169.0
MMS2_k127_3907487_0 long-chain fatty acid transport protein - - - 0.0000000002533 72.0
MMS2_k127_3907487_1 Propeptide_C25 - - - 0.0005528 49.0
MMS2_k127_3918812_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006261 282.0
MMS2_k127_3925775_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004084 256.0
MMS2_k127_3927988_0 translation release factor activity - - - 0.0000000000000000000000000003184 130.0
MMS2_k127_3928435_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 373.0
MMS2_k127_3929694_0 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000001698 193.0
MMS2_k127_3929694_1 Peptidase M15 - - - 0.0000000008023 65.0
MMS2_k127_3932600_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 420.0
MMS2_k127_3933212_0 Cellobiose phosphorylase K00702 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 377.0
MMS2_k127_3933212_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000001321 98.0
MMS2_k127_39338_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000001067 175.0
MMS2_k127_39338_1 heme binding K08259,K21471 - 3.4.24.75 0.00000000000000000000000001365 111.0
MMS2_k127_39338_2 Polymer-forming cytoskeletal - - - 0.00000000000000000007974 94.0
MMS2_k127_3954707_0 membrane protein (DUF2079) - - - 0.0000000000000000000000672 113.0
MMS2_k127_3961460_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 346.0
MMS2_k127_3967677_0 serine threonine protein kinase - - - 0.0000000000000000007781 99.0
MMS2_k127_3979231_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000007326 235.0
MMS2_k127_3992545_0 TIGRFAM phosphate ABC transporter K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 300.0
MMS2_k127_3992545_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 292.0
MMS2_k127_3992545_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000001324 160.0
MMS2_k127_3992545_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000001867 51.0
MMS2_k127_400253_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000007012 230.0
MMS2_k127_400253_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000007284 154.0
MMS2_k127_4022719_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 285.0
MMS2_k127_404500_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 313.0
MMS2_k127_4072860_0 transferase activity, transferring glycosyl groups K09809 - 2.7.8.12 0.000000000000000000000000000000000000000000000008443 186.0
MMS2_k127_4072860_1 Radical SAM domain protein - - - 0.00000000000000127 80.0
MMS2_k127_4075530_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 490.0
MMS2_k127_4075530_1 ATPase activity, coupled to transmembrane movement of substances K02120 - - 0.000000000000000000000000000000000001716 147.0
MMS2_k127_4075530_2 Rubrerythrin - - - 0.000000007248 62.0
MMS2_k127_4078289_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
MMS2_k127_4130388_0 PFAM glycosyl transferase, family 51 K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 398.0
MMS2_k127_4132597_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 381.0
MMS2_k127_4132597_1 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000003408 152.0
MMS2_k127_4132597_2 PFAM response regulator receiver - - - 0.00000000000000001489 87.0
MMS2_k127_4132597_3 Belongs to the UPF0235 family K09131 - - 0.00000000000002736 74.0
MMS2_k127_4132597_4 WD40-like Beta Propeller Repeat - - - 0.0000000000007779 78.0
MMS2_k127_4133833_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 419.0
MMS2_k127_4133833_1 MotA TolQ ExbB proton channel family K03561 - - 0.0000000000000000000000000000001272 131.0
MMS2_k127_4133833_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000009086 66.0
MMS2_k127_4133833_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000002408 64.0
MMS2_k127_4133833_4 4Fe-4S binding domain - - - 0.000003965 49.0
MMS2_k127_4136352_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000008599 186.0
MMS2_k127_4136352_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000009263 108.0
MMS2_k127_4136352_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.00000821 58.0
MMS2_k127_4142277_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 3.021e-239 749.0
MMS2_k127_4145280_0 EamA-like transporter family - - - 0.000000000000000000002646 104.0
MMS2_k127_4145280_1 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000485 68.0
MMS2_k127_4145280_2 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000002218 51.0
MMS2_k127_4151909_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.197e-202 637.0
MMS2_k127_4151909_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 317.0
MMS2_k127_4151909_2 - - - - 0.00000005622 57.0
MMS2_k127_4157051_0 Binding-protein-dependent transport system inner membrane component K17313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 291.0
MMS2_k127_4157051_1 ABC transporter (Permease K02025 - - 0.0000000000000000000000001056 109.0
MMS2_k127_418054_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 424.0
MMS2_k127_418363_0 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00000003808 64.0
MMS2_k127_4184934_0 Belongs to the OMP decarboxylase family. Type 2 subfamily K00762,K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000005839 254.0
MMS2_k127_4184934_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000007207 108.0
MMS2_k127_419514_0 Glycoside hydrolase family 24 - - - 0.00000006189 64.0
MMS2_k127_4203355_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 406.0
MMS2_k127_4203355_1 Belongs to the glycosyl hydrolase 18 family - - - 0.00001655 49.0
MMS2_k127_4204196_0 ABC transporter, transmembrane region K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 345.0
MMS2_k127_4204196_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000001278 237.0
MMS2_k127_4204196_2 PFAM MgtC SapB transporter K07507 - - 0.000000000000000000000000000001884 123.0
MMS2_k127_4208287_0 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000000001624 219.0
MMS2_k127_4208287_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000653 184.0
MMS2_k127_4211628_0 GTP-binding protein K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 447.0
MMS2_k127_4211841_0 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000006839 232.0
MMS2_k127_4212169_0 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 413.0
MMS2_k127_4212169_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0005081 44.0
MMS2_k127_4237112_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000004742 199.0
MMS2_k127_424182_0 Organic solvent tolerance protein OstA K04744 - - 0.0000000000000000000000003888 121.0
MMS2_k127_4247555_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 414.0
MMS2_k127_4247555_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 297.0
MMS2_k127_4271550_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002042 254.0
MMS2_k127_4271550_1 Mu-like prophage protein Com - - - 0.00005153 47.0
MMS2_k127_4297668_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000001662 233.0
MMS2_k127_4297668_1 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000007118 194.0
MMS2_k127_4297668_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000006648 127.0
MMS2_k127_4300663_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 623.0
MMS2_k127_4300663_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 516.0
MMS2_k127_4300663_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000102 181.0
MMS2_k127_4300663_3 PFAM FecR protein K01387 - 3.4.24.3 0.000000000000007018 87.0
MMS2_k127_4309289_0 Flagellar basal body K02390 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000000000000000000002059 122.0
MMS2_k127_4309289_1 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0004264 51.0
MMS2_k127_4316943_0 PFAM NDP-hexose 2,3-dehydratase K16435 - 4.2.1.159 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 425.0
MMS2_k127_4316943_1 PFAM oxidoreductase domain protein K13327 - 1.1.1.384 0.000000000000000000000000000000000000000000000000000000000000000000188 241.0
MMS2_k127_4316943_2 WxcM-like, C-terminal - - - 0.00000000000000000000000000000000000000000002502 164.0
MMS2_k127_4316943_3 cytidylyl-transferase K00983 - 2.7.7.43 0.0000000008792 68.0
MMS2_k127_4316943_4 Flavin containing amine oxidoreductase - - - 0.0000005356 55.0
MMS2_k127_4332818_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 357.0
MMS2_k127_4332818_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000002953 200.0
MMS2_k127_4332818_2 - - - - 0.000000000002254 78.0
MMS2_k127_4332818_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00001142 51.0
MMS2_k127_4335953_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 443.0
MMS2_k127_4335953_1 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000007646 72.0
MMS2_k127_4355404_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 547.0
MMS2_k127_4355404_1 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000005314 139.0
MMS2_k127_4367328_0 - - - - 0.000000000000000000001845 102.0
MMS2_k127_4367328_1 LemA family K03744 - - 0.000000000000000000008115 94.0
MMS2_k127_4367328_2 mechanosensitive ion channel - - - 0.000001117 52.0
MMS2_k127_4384222_0 - - - - 0.00000000000000000000000000000000000009167 145.0
MMS2_k127_4384222_1 - - - - 0.0000000000000000000000000000000001373 135.0
MMS2_k127_4384222_2 - - - - 0.0000000000000000002912 89.0
MMS2_k127_4396239_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004624 246.0
MMS2_k127_4396239_1 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001345 160.0
MMS2_k127_4396239_2 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000001986 71.0
MMS2_k127_4396739_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 332.0
MMS2_k127_4396739_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000005417 212.0
MMS2_k127_4396739_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001031 180.0
MMS2_k127_4396739_3 PFAM ribosomal protein L17 K02879 - - 0.0000000000000000000000003405 108.0
MMS2_k127_4396739_4 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002101 83.0
MMS2_k127_4397441_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001643 231.0
MMS2_k127_4397441_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000002284 185.0
MMS2_k127_4397441_2 response regulator - - - 0.000001773 55.0
MMS2_k127_4410450_0 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 359.0
MMS2_k127_4410450_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 342.0
MMS2_k127_4410900_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000001318 198.0
MMS2_k127_4410900_1 PFAM FecR protein - - - 0.000336 52.0
MMS2_k127_441490_0 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007506 269.0
MMS2_k127_441490_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000003853 170.0
MMS2_k127_4415137_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000596 273.0
MMS2_k127_4415137_1 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000002079 165.0
MMS2_k127_4417675_0 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 445.0
MMS2_k127_4417675_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000969 263.0
MMS2_k127_4417675_2 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.000000000000000000000000000000000000009548 147.0
MMS2_k127_4417675_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000001727 143.0
MMS2_k127_4417675_4 S-layer homology domain - - - 0.00000000000000001973 95.0
MMS2_k127_4422789_0 ABC transporter K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 320.0
MMS2_k127_4422789_1 PFAM Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000002 67.0
MMS2_k127_4435099_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003493 278.0
MMS2_k127_4435099_1 PFAM VanW family protein K18346 - - 0.000000000005985 75.0
MMS2_k127_4438435_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 527.0
MMS2_k127_4438435_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000003471 69.0
MMS2_k127_444032_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000669 261.0
MMS2_k127_444032_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000001129 143.0
MMS2_k127_4440674_0 metallopeptidase activity - - - 0.00000000000000000000000001324 123.0
MMS2_k127_4440674_1 PFAM Uncharacterised protein family (UPF0164) - - - 0.000000002987 63.0
MMS2_k127_4453693_0 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000000001239 210.0
MMS2_k127_4453693_1 Bacterial membrane protein YfhO - - - 0.00000000000001148 81.0
MMS2_k127_4467479_0 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01594,K13745 - 4.1.1.15,4.1.1.29,4.1.1.86 0.000001674 59.0
MMS2_k127_448217_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000000000000000001191 171.0
MMS2_k127_449406_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 420.0
MMS2_k127_449406_1 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000001805 117.0
MMS2_k127_449406_2 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000003387 113.0
MMS2_k127_449406_3 Radical SAM-linked protein - - - 0.00000000000000000000002277 104.0
MMS2_k127_4497755_0 Rho termination factor, N-terminal domain K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 299.0
MMS2_k127_4497755_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000003079 138.0
MMS2_k127_4501142_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 8.25e-216 690.0
MMS2_k127_4501142_1 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.00000000000000000000000000006794 123.0
MMS2_k127_4501142_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000001102 105.0
MMS2_k127_4501142_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000008734 89.0
MMS2_k127_4501142_4 TIGRFAM ComEC Rec2-related protein K02238 - - 0.00004045 52.0
MMS2_k127_4504529_0 ABC transporter, transmembrane region K06147,K11085 - - 0.0000000000000000000000000000000005559 133.0
MMS2_k127_4504529_2 O-methyltransferase activity K15257,K20444 - - 0.00000002049 64.0
MMS2_k127_4509387_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000004046 238.0
MMS2_k127_4509387_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00004872 46.0
MMS2_k127_4521181_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000004416 225.0
MMS2_k127_4521181_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000001245 192.0
MMS2_k127_4521181_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000000001712 141.0
MMS2_k127_4521181_3 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0001499 45.0
MMS2_k127_4527334_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000003416 256.0
MMS2_k127_4527334_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000007944 167.0
MMS2_k127_4530513_0 glycosyl transferase family - - - 0.00000000000000000008419 102.0
MMS2_k127_4531392_0 Protein phosphatase 2A homologues, catalytic domain. - - - 0.00000000000000000000000175 118.0
MMS2_k127_455015_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 482.0
MMS2_k127_455015_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002977 281.0
MMS2_k127_455015_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000008576 217.0
MMS2_k127_455824_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 609.0
MMS2_k127_455824_1 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000002458 183.0
MMS2_k127_4563309_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 476.0
MMS2_k127_4563309_1 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 462.0
MMS2_k127_4563309_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000005821 127.0
MMS2_k127_4576852_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 442.0
MMS2_k127_4584060_0 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000006042 136.0
MMS2_k127_4584060_1 Glycogen debranching enzyme - - - 0.00000000000000000000000001013 117.0
MMS2_k127_4584555_0 Histidine triad domain protein K02503 - - 0.00000000000000000000000000000000000000000003042 162.0
MMS2_k127_4584555_1 Cytochrome c - - - 0.0000000000000004969 83.0
MMS2_k127_4602309_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 369.0
MMS2_k127_4602309_1 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 351.0
MMS2_k127_4602309_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000003028 256.0
MMS2_k127_4602309_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000179 248.0
MMS2_k127_4602309_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000001656 109.0
MMS2_k127_4629268_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000002464 147.0
MMS2_k127_4629268_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000002095 102.0
MMS2_k127_4631239_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 404.0
MMS2_k127_4631239_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000226 268.0
MMS2_k127_4631239_2 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000001302 188.0
MMS2_k127_4631239_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000007761 153.0
MMS2_k127_46327_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 345.0
MMS2_k127_46327_1 NifU-like N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001651 214.0
MMS2_k127_46327_2 Psort location CytoplasmicMembrane, score 10.00 K07089 - - 0.000000000000000000000000005539 116.0
MMS2_k127_4648873_0 COG2089 Sialic acid synthase K01654,K18430 GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016740,GO:0016765,GO:0044238,GO:0071704,GO:1901576 2.5.1.101,2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 392.0
MMS2_k127_4648873_1 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 290.0
MMS2_k127_4650634_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 309.0
MMS2_k127_4650634_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000001788 62.0
MMS2_k127_4650634_2 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000004498 53.0
MMS2_k127_4651166_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000001423 148.0
MMS2_k127_4651166_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000002253 127.0
MMS2_k127_4651166_2 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000002953 87.0
MMS2_k127_4673931_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000012 252.0
MMS2_k127_4680720_0 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 323.0
MMS2_k127_4680720_1 Peptidase family C25 - - - 0.000006764 51.0
MMS2_k127_4680720_2 DnaJ molecular chaperone homology domain - - - 0.00004346 49.0
MMS2_k127_4691514_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 387.0
MMS2_k127_4691514_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000002162 181.0
MMS2_k127_4691764_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 323.0
MMS2_k127_4691764_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 248.0
MMS2_k127_4691764_2 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000000000000000000000000000009296 123.0
MMS2_k127_4691764_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000002124 87.0
MMS2_k127_4691764_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000004254 78.0
MMS2_k127_4699980_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000618 239.0
MMS2_k127_4699980_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000007201 135.0
MMS2_k127_4699980_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000003489 76.0
MMS2_k127_4707535_0 neurotransmitter:sodium symporter activity K03308 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 546.0
MMS2_k127_4707535_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 466.0
MMS2_k127_4707535_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005986 277.0
MMS2_k127_4707535_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 270.0
MMS2_k127_4707535_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000001621 109.0
MMS2_k127_4707535_5 Phosphodiester glycosidase - - - 0.00000000000896 76.0
MMS2_k127_4721747_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 297.0
MMS2_k127_4721747_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000003569 190.0
MMS2_k127_4738015_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1205.0
MMS2_k127_4738015_1 Cell envelope-like function transcriptional attenuator common domain protein - - - 0.00000000000000000000001451 105.0
MMS2_k127_4738015_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000006285 100.0
MMS2_k127_473861_0 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 409.0
MMS2_k127_473861_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003291 235.0
MMS2_k127_4740079_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 291.0
MMS2_k127_4740079_1 GTP-binding protein YchF K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005727 252.0
MMS2_k127_4740079_2 - - - - 0.0000000000000002027 86.0
MMS2_k127_4740079_3 Belongs to the peptidase M48B family K03799 - - 0.00000003135 55.0
MMS2_k127_4741864_0 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 451.0
MMS2_k127_4741864_1 iron ion homeostasis K03709,K04758 - - 0.000000000000000000000000000001145 123.0
MMS2_k127_4749593_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.00002524 56.0
MMS2_k127_4762249_0 Uncharacterized conserved protein (DUF2304) - - - 0.000000000008635 67.0
MMS2_k127_4762249_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000007676 72.0
MMS2_k127_4765608_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.761e-233 732.0
MMS2_k127_4765608_1 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 374.0
MMS2_k127_4765608_2 Prokaryotic diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000008967 76.0
MMS2_k127_4765608_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA - - - 0.000000001752 59.0
MMS2_k127_4770722_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000001165 202.0
MMS2_k127_4770722_1 Sigma-54 interaction domain - - - 0.00000000000003211 82.0
MMS2_k127_4770890_0 Belongs to the carbohydrate kinase PfkB family K00852,K21057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.15,2.7.1.213 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 368.0
MMS2_k127_4770890_1 Class ii aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000001166 179.0
MMS2_k127_4770890_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000002506 164.0
MMS2_k127_4778220_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000995 224.0
MMS2_k127_4778220_1 Belongs to the MlaE permease family K02066 - - 0.000002042 52.0
MMS2_k127_4778654_0 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000005326 201.0
MMS2_k127_4778654_1 PFAM Peptidase family M23 - - - 0.00000000000000000000000006723 109.0
MMS2_k127_4782951_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000009436 207.0
MMS2_k127_4782951_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000003758 151.0
MMS2_k127_4798180_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 496.0
MMS2_k127_4798180_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 456.0
MMS2_k127_4803201_0 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000414 113.0
MMS2_k127_4804604_0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000003252 154.0
MMS2_k127_4804604_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000008732 110.0
MMS2_k127_4804604_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000003855 87.0
MMS2_k127_483642_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000001596 139.0
MMS2_k127_4841115_0 pilus assembly protein K02662 - - 0.00000000000000000004666 102.0
MMS2_k127_4856039_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 588.0
MMS2_k127_4856039_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003127 280.0
MMS2_k127_4857276_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 506.0
MMS2_k127_4857276_1 NAD(P)H-binding K15894 - 4.2.1.115 0.0000000002337 62.0
MMS2_k127_4862316_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 433.0
MMS2_k127_4862316_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000008516 214.0
MMS2_k127_4862316_2 Peptidase family M20 M25 M40 K01258 - 3.4.11.4 0.000000000000000000000001781 107.0
MMS2_k127_4870799_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002641 246.0
MMS2_k127_4870799_2 transferase activity, transferring glycosyl groups - - - 0.00000002094 66.0
MMS2_k127_48750_0 PFAM Glycosyl K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000004791 206.0
MMS2_k127_4881829_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.121e-252 791.0
MMS2_k127_4881829_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000004671 151.0
MMS2_k127_4881829_2 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000003135 95.0
MMS2_k127_4881829_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000009878 69.0
MMS2_k127_4888163_0 Maf-like protein K06287 - - 0.000000000000000000000000000000000000001327 153.0
MMS2_k127_4888163_1 Peptidase family M23 - - - 0.00000000000000000000000000000000001506 145.0
MMS2_k127_4888163_2 - - - - 0.000005648 56.0
MMS2_k127_4894479_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 328.0
MMS2_k127_4894479_1 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000001557 60.0
MMS2_k127_4901505_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05539,K05540 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 314.0
MMS2_k127_4901505_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000002884 191.0
MMS2_k127_4901505_2 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000006073 156.0
MMS2_k127_4901505_3 UPF0056 membrane protein K05595 - - 0.000000000000000000000000107 113.0
MMS2_k127_4901505_4 Domain of unknown function(DUF2779) - - - 0.0000000000001549 73.0
MMS2_k127_4902992_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 323.0
MMS2_k127_4902992_1 single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000000000000000000000000002974 159.0
MMS2_k127_4907366_0 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000001563 205.0
MMS2_k127_4907366_1 ABC transporter, ATP-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000006955 193.0
MMS2_k127_492209_0 COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000001446 92.0
MMS2_k127_492209_1 PAS fold - - - 0.000000000000001032 83.0
MMS2_k127_4947361_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000009864 195.0
MMS2_k127_4953613_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 444.0
MMS2_k127_4953613_1 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000789 203.0
MMS2_k127_4953613_2 alpha beta alpha domain I - - - 0.0000000000000000000000000000000000000000000000000001497 191.0
MMS2_k127_4955674_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01640,K01666 - 4.1.3.39,4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 432.0
MMS2_k127_4955674_1 glycerophosphoryl diester phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002664 245.0
MMS2_k127_4955674_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000006761 172.0
MMS2_k127_4963965_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.000000000000000000611 99.0
MMS2_k127_4982736_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 8.015e-219 688.0
MMS2_k127_4982736_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 323.0
MMS2_k127_4986063_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 557.0
MMS2_k127_4986063_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000004675 269.0
MMS2_k127_4986063_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 267.0
MMS2_k127_4986063_3 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000004622 208.0
MMS2_k127_4986063_4 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000006152 183.0
MMS2_k127_4987897_0 COG0534 Na -driven multidrug efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000377 226.0
MMS2_k127_4987897_1 Carboxylesterase family - - - 0.000000000594 66.0
MMS2_k127_498902_0 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000907 159.0
MMS2_k127_4989987_0 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000284 285.0
MMS2_k127_4989987_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 267.0
MMS2_k127_4989987_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K00697,K01087,K16055 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000001219 186.0
MMS2_k127_4989987_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000002644 165.0
MMS2_k127_4991159_0 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 454.0
MMS2_k127_4991159_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000002294 73.0
MMS2_k127_4992438_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001925 259.0
MMS2_k127_4992438_1 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005327 252.0
MMS2_k127_4995103_0 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000001026 207.0
MMS2_k127_4995103_1 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K03763 - 2.7.7.7 0.000000000000000000000000000000000000000000003109 170.0
MMS2_k127_4995138_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 472.0
MMS2_k127_5003592_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003611 252.0
MMS2_k127_5009084_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000005293 159.0
MMS2_k127_5009084_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000008867 78.0
MMS2_k127_5015900_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 378.0
MMS2_k127_5015900_1 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.00000000005157 68.0
MMS2_k127_5016111_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000002728 228.0
MMS2_k127_5016111_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000001502 145.0
MMS2_k127_5016111_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000006057 49.0
MMS2_k127_505357_0 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000003313 213.0
MMS2_k127_505357_1 Phosphoheptose isomerase K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000001658 171.0
MMS2_k127_505357_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000006351 106.0
MMS2_k127_505357_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000001188 67.0
MMS2_k127_505357_4 Transposase IS200 like K07491 - - 0.0004646 47.0
MMS2_k127_50584_0 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 353.0
MMS2_k127_50584_1 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001574 278.0
MMS2_k127_511404_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001398 206.0
MMS2_k127_511404_1 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000003387 190.0
MMS2_k127_511404_2 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000002538 115.0
MMS2_k127_514499_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 457.0
MMS2_k127_514499_1 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000002491 80.0
MMS2_k127_514499_2 Sporulation related domain - - - 0.0000000118 59.0
MMS2_k127_526227_0 Glycosyl hydrolase family 70 K01142,K01176 - 3.1.11.2,3.2.1.1 0.00000408 59.0
MMS2_k127_526227_1 cellulose binding - - - 0.0001969 49.0
MMS2_k127_547208_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000002829 185.0
MMS2_k127_553296_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000077 232.0
MMS2_k127_553296_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000001009 149.0
MMS2_k127_553296_2 tRNA processing K06864 - - 0.000000000000000000000003333 103.0
MMS2_k127_571288_0 Polysaccharide biosynthesis protein K01784,K02473,K03274 - 5.1.3.2,5.1.3.20,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 306.0
MMS2_k127_571288_1 COG0463 Glycosyltransferases involved in cell wall biogenesis K20444 - - 0.00000000000000000000000001604 120.0
MMS2_k127_571288_2 Glycosyltransferase like family 2 - - - 0.0000000000006623 70.0
MMS2_k127_587048_0 serine-type endopeptidase activity K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 302.0
MMS2_k127_587048_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000005878 83.0
MMS2_k127_587048_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.4.21.53 0.000000000002197 68.0
MMS2_k127_605181_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 402.0
MMS2_k127_605181_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000008812 69.0
MMS2_k127_610983_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 466.0
MMS2_k127_610983_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 421.0
MMS2_k127_610983_2 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 298.0
MMS2_k127_610983_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000006614 59.0
MMS2_k127_618724_0 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004365 274.0
MMS2_k127_618724_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000002563 188.0
MMS2_k127_618724_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001899 167.0
MMS2_k127_618724_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000001377 144.0
MMS2_k127_618724_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000002139 121.0
MMS2_k127_618724_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001536 76.0
MMS2_k127_622091_0 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000004433 207.0
MMS2_k127_622091_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000001838 168.0
MMS2_k127_62857_0 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 467.0
MMS2_k127_62857_1 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007314 252.0
MMS2_k127_62857_2 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000001847 177.0
MMS2_k127_676418_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 545.0
MMS2_k127_688375_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 376.0
MMS2_k127_688375_1 phosphorelay signal transduction system K02437 - - 0.0000000000000000000002181 101.0
MMS2_k127_699762_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000002859 69.0
MMS2_k127_718701_0 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 330.0
MMS2_k127_718701_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000005453 154.0
MMS2_k127_718701_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000004471 110.0
MMS2_k127_732836_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000004594 144.0
MMS2_k127_732836_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000006263 54.0
MMS2_k127_738475_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006738 269.0
MMS2_k127_738475_1 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001357 253.0
MMS2_k127_740517_0 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 253.0
MMS2_k127_740517_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000007638 184.0
MMS2_k127_740517_2 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000000000000000000001983 159.0
MMS2_k127_740517_3 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000004617 137.0
MMS2_k127_743991_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 493.0
MMS2_k127_745356_0 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.0000000000000000000000000000000000000001068 158.0
MMS2_k127_745356_1 Putative MetA-pathway of phenol degradation - - - 0.0000002083 62.0
MMS2_k127_749193_0 ABC transporter, substratebinding protein K02035 - - 0.0000000000000000000000000000003025 129.0
MMS2_k127_749193_1 general secretion pathway protein G K02456 - - 0.0000000008855 65.0
MMS2_k127_764786_0 long-chain fatty acid transporting porin activity - - - 0.000000000373 74.0
MMS2_k127_77038_0 peptidyl-tyrosine sulfation - - - 0.00001596 57.0
MMS2_k127_780769_0 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 320.0
MMS2_k127_780769_1 aspartic-type endopeptidase activity K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000001097 218.0
MMS2_k127_780769_2 Septum formation initiator K13052 - - 0.0002794 47.0
MMS2_k127_790175_0 Glycosyl transferase 4-like domain K06338,K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 383.0
MMS2_k127_790175_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000000000004576 206.0
MMS2_k127_790175_2 glycoside hydrolase, family 65 domain protein K10231 - 2.4.1.230 0.000000000000001103 79.0
MMS2_k127_796341_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 428.0
MMS2_k127_796341_1 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 375.0
MMS2_k127_800430_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.047e-218 694.0
MMS2_k127_800430_1 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000001559 244.0
MMS2_k127_800430_2 PFAM Bacterial extracellular solute-binding, family 1 K02027 - - 0.00000000000000000000000000000000000000000008689 164.0
MMS2_k127_80324_0 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 546.0
MMS2_k127_80324_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000003656 192.0
MMS2_k127_803870_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000137 251.0
MMS2_k127_803870_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000001031 180.0
MMS2_k127_803870_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000005843 154.0
MMS2_k127_803870_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000001505 154.0
MMS2_k127_803870_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000003706 137.0
MMS2_k127_803870_5 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001689 116.0
MMS2_k127_803870_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000001721 112.0
MMS2_k127_803870_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000015 106.0
MMS2_k127_803870_8 Ribosomal L29 protein K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0001414 46.0
MMS2_k127_804531_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 491.0
MMS2_k127_804531_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 373.0
MMS2_k127_804531_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 340.0
MMS2_k127_804531_3 Ribosomal L32p protein family K02911 - - 0.000000000006282 67.0
MMS2_k127_804531_4 Uncharacterized ACR, COG1399 K07040 - - 0.00006289 46.0
MMS2_k127_804721_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 484.0
MMS2_k127_809753_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 349.0
MMS2_k127_809753_1 auxin efflux carrier K07088 - - 0.0000000000000000000001524 108.0
MMS2_k127_809753_2 Glutathione peroxidase - - - 0.0000114 52.0
MMS2_k127_809753_3 OstA-like protein K09774 - - 0.00001253 56.0
MMS2_k127_809753_4 Lipopolysaccharide-assembly, LptC-related - - - 0.0009532 50.0
MMS2_k127_825342_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 379.0
MMS2_k127_825342_1 PFAM Flagellar assembly protein FliH Type III secretion system HrpE K02411 - - 0.0000000000000000000000001535 115.0
MMS2_k127_825342_2 The M ring may be actively involved in energy transduction K02409 - - 0.0003108 48.0
MMS2_k127_829362_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 374.0
MMS2_k127_829362_1 NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006822 265.0
MMS2_k127_85342_0 Psort location Cytoplasmic, score K01163 - - 0.000000000000005069 82.0
MMS2_k127_85342_1 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000166 52.0
MMS2_k127_859743_0 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006413 278.0
MMS2_k127_859743_1 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
MMS2_k127_859743_2 electron transport chain K02560,K03613,K10773 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 2.3.1.243,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000004144 231.0
MMS2_k127_859743_3 FMN binding K03612 - - 0.000000000000000000000000000000000000008752 151.0
MMS2_k127_859743_4 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000002249 146.0
MMS2_k127_867218_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002223 246.0
MMS2_k127_868231_0 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
MMS2_k127_868231_1 Hydrolase, tatd K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000007019 173.0
MMS2_k127_868231_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000001961 116.0
MMS2_k127_873763_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 327.0
MMS2_k127_889701_0 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000000000000000000001103 178.0
MMS2_k127_889701_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000003354 176.0
MMS2_k127_893312_0 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 553.0
MMS2_k127_893312_1 - K07341 - - 0.0000000000000000005891 92.0
MMS2_k127_893312_2 DNA binding domain, excisionase family - - - 0.0001145 48.0
MMS2_k127_89621_0 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000002264 123.0
MMS2_k127_89621_1 Protein of unknown function (DUF559) - - - 0.0000000000000000000000001146 109.0
MMS2_k127_897982_0 Cadherin-like beta sandwich domain - - - 0.000000000000000000005493 106.0
MMS2_k127_897982_1 S-layer homology domain - - - 0.000005747 59.0
MMS2_k127_904775_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 399.0
MMS2_k127_904775_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 366.0
MMS2_k127_904775_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000004398 230.0
MMS2_k127_904775_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000001867 84.0
MMS2_k127_904775_4 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000001617 80.0
MMS2_k127_908027_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
MMS2_k127_908027_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509 5.1.3.20 0.000000000000000428 80.0
MMS2_k127_909053_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000001742 90.0
MMS2_k127_917549_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 433.0
MMS2_k127_934823_0 Nickel-dependent hydrogenase - - - 1.677e-207 652.0
MMS2_k127_934823_1 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.00000000000000000000000000000000002699 136.0
MMS2_k127_934823_2 maturation protease K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.00000000000000000000000000000002502 131.0
MMS2_k127_956735_0 Sporulation initiation inhibitor protein Soj K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 327.0
MMS2_k127_956735_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000009066 192.0
MMS2_k127_956735_2 Outer membrane protein protective antigen OMA87 K07277 - - 0.00000000003913 70.0
MMS2_k127_957474_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 320.0
MMS2_k127_961252_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 376.0
MMS2_k127_961252_1 Putative DNA-binding domain - - - 0.000000000001158 76.0
MMS2_k127_961252_2 Transcriptional regulator K03655 - 3.6.4.12 0.0000002904 60.0
MMS2_k127_96288_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000006883 238.0
MMS2_k127_96288_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000007652 72.0
MMS2_k127_964201_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 365.0
MMS2_k127_964201_1 Subtilase family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000002065 249.0
MMS2_k127_965423_0 Thioredoxin-like - - - 0.0000000000000000000000000000000000001059 147.0
MMS2_k127_965423_1 Putative Fe-S cluster K03616 - - 0.0000000000000000000000000000000000296 137.0
MMS2_k127_965423_2 PFAM Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000006303 89.0
MMS2_k127_968553_0 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 414.0
MMS2_k127_968553_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000745 123.0
MMS2_k127_969231_0 Elongation factor Tu domain 2 K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 471.0
MMS2_k127_971574_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000001221 233.0
MMS2_k127_971574_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000001051 134.0
MMS2_k127_971574_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000001516 67.0
MMS2_k127_975563_0 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000000000000001941 244.0
MMS2_k127_975563_1 NAD-dependent epimerase dehydratase K01709,K01710 - 4.2.1.45,4.2.1.46 0.00000000000000000000000000000000000000000000002305 173.0
MMS2_k127_975563_2 PFAM glycosyl transferase group 1 - - - 0.00000000007885 66.0
MMS2_k127_976876_0 MFS/sugar transport protein K03292 - - 0.00000000000000000000000000000000000002244 151.0
MMS2_k127_976876_1 Belongs to the UPF0102 family K07460 - - 0.0000000000000000003222 91.0
MMS2_k127_976876_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000001497 85.0
MMS2_k127_98421_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000004094 94.0
MMS2_k127_98421_1 Peptidase, M23 - - - 0.0000000000001667 78.0
MMS2_k127_98421_2 Psort location Cytoplasmic, score 7.50 - - - 0.0008741 42.0
MMS2_k127_989624_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000002156 141.0
MMS2_k127_989624_1 Pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000002179 95.0
MMS2_k127_989624_2 Psort location Cytoplasmic, score K09117 - - 0.00000000000000000003194 96.0
MMS2_k127_998455_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 507.0
MMS2_k127_998455_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 338.0