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Overview

ID MAG02761
Name MMS2_bin.78
Sample SMP0065
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order Thermoplasmatales
Family Thermoplasmataceae
Genus WAQW01
Species
Assembly information
Completeness (%) 72.61
Contamination (%) 0.64
GC content (%) 42.0
N50 (bp) 4,909
Genome size (bp) 1,141,380

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1185

Gene name Description KEGG GOs EC E-value Score Sequence
MMS2_k127_1002531_0 Methyltransferase domain - - - 0.00000000001492 74.0
MMS2_k127_1002531_1 glycosyl transferase family 2 - - - 0.0002596 52.0
MMS2_k127_1012132_0 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 572.0
MMS2_k127_1012132_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 454.0
MMS2_k127_1012132_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000003307 167.0
MMS2_k127_1012132_3 acyl-CoA dehydrogenase - - - 0.00001374 53.0
MMS2_k127_1019040_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.885e-209 672.0
MMS2_k127_1019040_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000004 84.0
MMS2_k127_1019040_2 - - - - 0.00000000094 62.0
MMS2_k127_1024347_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.355e-200 638.0
MMS2_k127_1024347_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 499.0
MMS2_k127_1024347_2 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000165 277.0
MMS2_k127_1024347_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000005847 256.0
MMS2_k127_1024347_4 PRC-barrel domain protein - - - 0.000000000000000173 81.0
MMS2_k127_1024415_0 DEAD/H associated K03724 - - 0.0 1593.0
MMS2_k127_1024415_1 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 362.0
MMS2_k127_1024415_2 Protein of unknown function (DUF359) K09735 - - 0.0000000000000000000000000000002993 127.0
MMS2_k127_1024415_3 structural constituent of ribosome K02974 - - 0.00000000000000000000000000006342 118.0
MMS2_k127_1024415_4 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000000889 87.0
MMS2_k127_1026944_0 Heat shock 70 kDa protein K04043 - - 1.882e-275 861.0
MMS2_k127_1026944_1 Putative RNA methylase family UPF0020 K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000000000000000000000002892 241.0
MMS2_k127_1026944_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000005152 123.0
MMS2_k127_1026944_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000007645 51.0
MMS2_k127_1027776_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 353.0
MMS2_k127_1027776_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 304.0
MMS2_k127_1027776_2 Met-10+ like-protein K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000001315 233.0
MMS2_k127_1027776_3 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000003628 95.0
MMS2_k127_1033158_0 TCP-1/cpn60 chaperonin family K22447 - - 2.199e-264 822.0
MMS2_k127_1033158_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000362 76.0
MMS2_k127_1037903_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 319.0
MMS2_k127_1037903_1 Pantothenic acid kinase K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 308.0
MMS2_k127_1037903_2 - - - - 0.00000006117 57.0
MMS2_k127_1061927_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006194 289.0
MMS2_k127_1061927_1 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.000000000000000000000000000000000000000000000001288 188.0
MMS2_k127_1061927_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000006967 132.0
MMS2_k127_1061927_3 regulatory protein, arsR K21903 - - 0.000000000000000001065 90.0
MMS2_k127_1085597_0 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 495.0
MMS2_k127_1085597_1 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003628 244.0
MMS2_k127_1091861_0 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000004283 251.0
MMS2_k127_1091861_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000002461 182.0
MMS2_k127_1091861_2 Methyltransferase domain - - - 0.00000000000000000000002146 106.0
MMS2_k127_1091861_3 - - - - 0.00000008262 57.0
MMS2_k127_1094476_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 376.0
MMS2_k127_1094476_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 312.0
MMS2_k127_1094476_2 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile K04796 - - 0.00000000000000000000000000009454 117.0
MMS2_k127_1097097_0 peptidase K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007853 265.0
MMS2_k127_1097097_1 - - - - 0.000000000001177 72.0
MMS2_k127_1097097_2 Uncharacterised ACR, YggU family COG1872 K09131 - - 0.0000008475 53.0
MMS2_k127_1099888_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001022 283.0
MMS2_k127_1099888_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000008507 235.0
MMS2_k127_1099888_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000001103 160.0
MMS2_k127_1105804_0 Penicillin amidase K01434 - 3.5.1.11 2.059e-238 750.0
MMS2_k127_1121756_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 264.0
MMS2_k127_1121756_1 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000001514 163.0
MMS2_k127_1121756_2 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000001033 133.0
MMS2_k127_1132188_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 538.0
MMS2_k127_1132188_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 313.0
MMS2_k127_1132188_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000001814 175.0
MMS2_k127_1145820_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 542.0
MMS2_k127_1145820_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000002074 173.0
MMS2_k127_1145820_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000003582 161.0
MMS2_k127_1145820_3 Regulatory protein Crp K07730 - - 0.0000000000000000000000000000000000000001329 159.0
MMS2_k127_1145820_4 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000002888 123.0
MMS2_k127_1209103_0 Radical SAM domain protein K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 430.0
MMS2_k127_1209103_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000003333 181.0
MMS2_k127_1216091_0 Peptidyl-prolyl cis-trans K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000511 238.0
MMS2_k127_1216091_1 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
MMS2_k127_1216091_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000005954 177.0
MMS2_k127_1216091_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000005932 169.0
MMS2_k127_1216091_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.0000000000000000000000000000000001145 136.0
MMS2_k127_1216091_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000000002591 107.0
MMS2_k127_1216091_6 COG1012 NAD-dependent aldehyde dehydrogenases K00128 - 1.2.1.3 0.0000000000004905 70.0
MMS2_k127_1216091_7 sequence-specific DNA binding - - - 0.0001134 46.0
MMS2_k127_1239884_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 383.0
MMS2_k127_1239884_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001357 270.0
MMS2_k127_1239884_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000002035 151.0
MMS2_k127_1239884_3 - - - - 0.0000000000000001544 83.0
MMS2_k127_1251568_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 1.708e-229 719.0
MMS2_k127_1251568_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 553.0
MMS2_k127_1251568_2 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001632 271.0
MMS2_k127_1251568_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000000001495 219.0
MMS2_k127_1251568_4 ATPases associated with a variety of cellular activities K09013 - - 0.0000000000000000000000000000002309 124.0
MMS2_k127_1251568_5 HTH domain - - - 0.00000000000000000000000000638 118.0
MMS2_k127_1273991_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 384.0
MMS2_k127_1273991_1 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 324.0
MMS2_k127_1273991_2 PFAM Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000002938 143.0
MMS2_k127_1273991_3 prephenate dehydrogenase (NADP+) activity K00210 - 1.3.1.12 0.000000000000000000000000000002726 128.0
MMS2_k127_1273991_4 Amino acid permease - - - 0.0000000000000001867 91.0
MMS2_k127_1273991_5 Chorismate mutase type II - - - 0.00000000002748 72.0
MMS2_k127_1318820_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000007241 232.0
MMS2_k127_1318820_1 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000005453 213.0
MMS2_k127_1318820_2 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 - - 0.00000000000000000000000000000004382 130.0
MMS2_k127_1318820_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000005865 110.0
MMS2_k127_1318820_4 - - - - 0.0000000000188 70.0
MMS2_k127_1338609_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 428.0
MMS2_k127_1338609_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 427.0
MMS2_k127_1338609_2 GTPase of unknown function C-terminal K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 364.0
MMS2_k127_1338609_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 275.0
MMS2_k127_1338609_4 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005468 269.0
MMS2_k127_1338609_5 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001633 248.0
MMS2_k127_1338609_6 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000000000000000000000006602 186.0
MMS2_k127_1338609_7 protein, homolog of Cu resistance protein CopC - - - 0.00000000000000000000000000008669 121.0
MMS2_k127_134080_0 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 305.0
MMS2_k127_134080_1 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 276.0
MMS2_k127_1369982_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 492.0
MMS2_k127_1369982_1 - - - - 0.000000000000000000009778 94.0
MMS2_k127_1369982_2 Major facilitator superfamily - - - 0.0000000000000000000152 105.0
MMS2_k127_1369982_3 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000001164 89.0
MMS2_k127_1369982_4 membrane transporter protein K07090 - - 0.00003428 49.0
MMS2_k127_1425693_0 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000003357 252.0
MMS2_k127_1425693_1 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000008914 221.0
MMS2_k127_1425693_2 FAD linked K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000002325 222.0
MMS2_k127_1425693_3 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000008827 153.0
MMS2_k127_1425693_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000004241 109.0
MMS2_k127_143143_0 Bacterial extracellular solute-binding protein K17311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 525.0
MMS2_k127_143143_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 295.0
MMS2_k127_143143_2 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
MMS2_k127_143143_3 GtrA-like protein K00786 - - 0.00000363 55.0
MMS2_k127_1447930_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000009389 218.0
MMS2_k127_1447930_1 ABC-2 family transporter protein K01992,K19341 - - 0.0006659 52.0
MMS2_k127_1468539_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 603.0
MMS2_k127_1468539_1 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000003245 197.0
MMS2_k127_1468539_2 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000007377 160.0
MMS2_k127_1510803_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 297.0
MMS2_k127_1510803_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
MMS2_k127_1510803_2 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000008535 213.0
MMS2_k127_1510803_3 HIT domain - - - 0.000000000000000000000000001859 117.0
MMS2_k127_1510803_4 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000001262 100.0
MMS2_k127_1549078_0 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity) K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000005054 269.0
MMS2_k127_1549078_1 - - - - 0.000000000000001645 78.0
MMS2_k127_1600896_0 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 361.0
MMS2_k127_1600896_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000003351 219.0
MMS2_k127_1608715_0 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 469.0
MMS2_k127_1608715_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 455.0
MMS2_k127_1652559_0 Biotin-lipoyl like K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 382.0
MMS2_k127_1652559_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000002356 183.0
MMS2_k127_1652559_2 Pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000001159 168.0
MMS2_k127_1661605_0 Catalyzes the transfer of the formyl group from N- formylglutamate to tetrahydrofolate (THF) to yield 5- formyltetrahydrofolate (5-CHO-THF) and glutamate (Glu). The triglutamate form of 5-CHO-THF (5-CHO-THF-Glu3) can also be used as substrate. It can also catalyzes the transfer of the formimino group from N-formiminoglutamate to tetrahydrofolate (THF) to yield 5-formiminotetrahydrofolate (5-NH CH-THF) and glutamate (Glu). It can replace YgfA to catalyzes the irreversible ATP-dependent transformation of 5-CHO-THF to form 5,10-methenyltetrahydrofolate (5,10-CH THF) K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 403.0
MMS2_k127_1661605_1 Acetyltransferase - - - 0.00000000000000000000000000000000000004117 147.0
MMS2_k127_1661605_2 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000001808 134.0
MMS2_k127_1661605_3 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000003279 125.0
MMS2_k127_1672187_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 580.0
MMS2_k127_1672187_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009936 262.0
MMS2_k127_1672187_2 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000004576 218.0
MMS2_k127_1672187_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000002025 90.0
MMS2_k127_1685955_0 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 353.0
MMS2_k127_1685955_1 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000201 70.0
MMS2_k127_1685955_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000557 56.0
MMS2_k127_1685955_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000001371 51.0
MMS2_k127_1685955_4 Peptidase A4 family - - - 0.0001874 54.0
MMS2_k127_1732381_0 Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000009246 185.0
MMS2_k127_1732381_1 ATPases associated with a variety of cellular activities K17314 - - 0.000000000000000000000002502 106.0
MMS2_k127_1732381_2 Thermopsin K01385 - 3.4.23.42 0.000004124 58.0
MMS2_k127_174069_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 351.0
MMS2_k127_174069_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 307.0
MMS2_k127_174069_2 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000007908 166.0
MMS2_k127_174069_3 - - - - 0.00000000000000003031 85.0
MMS2_k127_174069_4 protein conserved in archaea K09723 - - 0.00000000000000003368 89.0
MMS2_k127_1777292_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1924.0
MMS2_k127_1777292_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 529.0
MMS2_k127_1777292_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 480.0
MMS2_k127_1777292_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000003015 264.0
MMS2_k127_1777292_4 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000214 125.0
MMS2_k127_1777292_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000000000007279 106.0
MMS2_k127_1786560_0 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 553.0
MMS2_k127_1786560_1 PFAM Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 447.0
MMS2_k127_1786560_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 435.0
MMS2_k127_1786560_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 398.0
MMS2_k127_1786560_4 Methyltransferase domain K07579 - - 0.000000000000000000000000000000000000000003846 161.0
MMS2_k127_1786560_5 - - - - 0.0000000000000000000000000000000236 128.0
MMS2_k127_1786560_6 snRNP Sm proteins K04796 - - 0.000000000000000000000000179 106.0
MMS2_k127_1786560_8 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000227 81.0
MMS2_k127_1786560_9 - - - - 0.0000000001979 62.0
MMS2_k127_18115_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000001702 235.0
MMS2_k127_18115_1 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000001161 225.0
MMS2_k127_18115_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000004619 145.0
MMS2_k127_1813073_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 341.0
MMS2_k127_1813073_1 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000001086 175.0
MMS2_k127_1813073_2 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.0000000000000000002436 90.0
MMS2_k127_1817734_0 YHS domain K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 516.0
MMS2_k127_1817734_1 - - - - 0.00000000000000000000000000000000000002109 152.0
MMS2_k127_1817734_2 Archaeal TRASH domain - - - 0.00000000000000000004049 96.0
MMS2_k127_1817734_3 Protein of unknown function (DUF3800) - - - 0.000000000000000006992 91.0
MMS2_k127_1817734_4 YHS domain - - - 0.0000000001788 62.0
MMS2_k127_1819328_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 373.0
MMS2_k127_1819328_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003953 269.0
MMS2_k127_1819328_2 ThiS family - - - 0.0000006716 54.0
MMS2_k127_1819328_3 HAD-hyrolase-like K07025 - - 0.00005332 45.0
MMS2_k127_1874648_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002654 261.0
MMS2_k127_1874648_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000009727 175.0
MMS2_k127_1877649_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 433.0
MMS2_k127_1877649_1 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K11181 GO:0003674,GO:0003824,GO:0005575,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016002,GO:0016020,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0044237,GO:0050311,GO:0055114 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007561 287.0
MMS2_k127_1877649_2 GPR1 FUN34 yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000137 248.0
MMS2_k127_1877649_3 PFAM nitrite and sulphite reductase 4Fe-4S K11180 GO:0005575,GO:0016020 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000324 247.0
MMS2_k127_1877649_4 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000008466 189.0
MMS2_k127_1877649_5 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.000000000000000000000000000000000005823 139.0
MMS2_k127_1877649_6 DsrE/DsrF-like family - - - 0.000000000000000000000000000009084 122.0
MMS2_k127_1877649_7 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000604 91.0
MMS2_k127_1877649_8 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules - - - 0.00000000000000001839 83.0
MMS2_k127_1877649_9 PFAM Nitrate reductase gamma subunit - - - 0.000000000000001765 85.0
MMS2_k127_191118_0 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 567.0
MMS2_k127_191118_1 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 513.0
MMS2_k127_191118_10 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000004045 202.0
MMS2_k127_191118_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000003273 152.0
MMS2_k127_191118_12 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000001127 154.0
MMS2_k127_191118_13 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000000001524 85.0
MMS2_k127_191118_14 2TM domain - - - 0.00000000000002278 76.0
MMS2_k127_191118_15 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000009573 56.0
MMS2_k127_191118_16 Double zinc ribbon - - - 0.0005955 49.0
MMS2_k127_191118_2 helicase superfamily c-terminal domain K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 370.0
MMS2_k127_191118_3 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 319.0
MMS2_k127_191118_4 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 328.0
MMS2_k127_191118_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 317.0
MMS2_k127_191118_6 structural constituent of ribosome K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 306.0
MMS2_k127_191118_7 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 295.0
MMS2_k127_191118_8 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000936 264.0
MMS2_k127_191118_9 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000001931 214.0
MMS2_k127_1918450_0 chorismate binding enzyme K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000001167 253.0
MMS2_k127_1918450_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000001088 87.0
MMS2_k127_1931283_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 1.001e-222 703.0
MMS2_k127_1931283_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 603.0
MMS2_k127_1931283_2 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 393.0
MMS2_k127_1931283_3 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002447 285.0
MMS2_k127_1931283_4 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000004874 162.0
MMS2_k127_1931283_5 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000001573 159.0
MMS2_k127_1931283_6 - - - - 0.00000000599 60.0
MMS2_k127_1953651_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 299.0
MMS2_k127_1953651_1 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005922 276.0
MMS2_k127_1953651_2 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000006141 195.0
MMS2_k127_1953651_3 Ta0938 - - - 0.00000000000000000000000000003833 118.0
MMS2_k127_1953651_4 Phosphotransferase enzyme family K06979 - - 0.000000000000000000000007635 112.0
MMS2_k127_1953651_5 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.00002824 51.0
MMS2_k127_199923_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 357.0
MMS2_k127_199923_1 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000002958 201.0
MMS2_k127_199923_2 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.000000000000000002875 86.0
MMS2_k127_2008782_0 Thioesterase superfamily K01073 - 3.1.2.20 0.00000000000000000000000000000000000000000000000001472 184.0
MMS2_k127_2008782_1 - - - - 0.00000000000000000001398 103.0
MMS2_k127_2008782_2 - - - - 0.0000000000000000000345 94.0
MMS2_k127_2008782_3 AAA-like domain K06915 - - 0.00000000001495 77.0
MMS2_k127_2009391_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 515.0
MMS2_k127_2009391_1 membrane-associated Zn-dependent proteases 1 - - - 0.000000000000008553 80.0
MMS2_k127_2031671_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.206e-245 776.0
MMS2_k127_2031671_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 610.0
MMS2_k127_2031671_2 histidine ammonia-lyase activity K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 497.0
MMS2_k127_2031671_3 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 476.0
MMS2_k127_2031671_4 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 374.0
MMS2_k127_2031671_5 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 312.0
MMS2_k127_2031671_6 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000002008 188.0
MMS2_k127_2031671_7 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000000000000005686 177.0
MMS2_k127_2031671_8 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - - 0.0000000000000000000000000000000000000000000005685 166.0
MMS2_k127_2031671_9 ribosomal small subunit binding - - - 0.00000000000000005517 88.0
MMS2_k127_2084624_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 581.0
MMS2_k127_2084624_1 Ras family K07890 - - 0.0000000000003275 80.0
MMS2_k127_2084624_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000005728 68.0
MMS2_k127_2112898_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 421.0
MMS2_k127_2112898_1 PFAM elongation factor Tu, domain 2 protein - - - 0.00000000000000000000000000000000000000000000000000000000003634 217.0
MMS2_k127_2112898_2 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000008106 211.0
MMS2_k127_2112898_3 Segregation and condensation protein K01011,K06024 - 2.8.1.1,2.8.1.2 0.000000000000000000000000002637 117.0
MMS2_k127_2112898_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000008181 74.0
MMS2_k127_21193_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 404.0
MMS2_k127_21193_1 helicase superfamily c-terminal domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000212 222.0
MMS2_k127_21193_2 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000001406 192.0
MMS2_k127_2119407_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 508.0
MMS2_k127_2119407_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 385.0
MMS2_k127_2119407_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 360.0
MMS2_k127_2119407_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 358.0
MMS2_k127_2119407_4 Met-10+ like-protein K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000001498 256.0
MMS2_k127_2119407_5 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.0000000000000000000000000000000000000000000000000000000000001291 218.0
MMS2_k127_2119407_6 Glycosyl transferase family 21 K00786 - - 0.000000000000000000000000000000000000000000000000000000000004299 214.0
MMS2_k127_2119407_7 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000001327 126.0
MMS2_k127_2127356_0 Arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 346.0
MMS2_k127_2127356_1 structural constituent of ribosome K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 284.0
MMS2_k127_2127356_2 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000002568 129.0
MMS2_k127_2127356_3 - - - - 0.00000001795 57.0
MMS2_k127_2127356_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000029 56.0
MMS2_k127_2167722_0 Psort location Cytoplasmic, score 8.87 K20074 - 3.1.3.16 0.000000000000000000000000000000004854 138.0
MMS2_k127_2167722_1 Serine Threonine protein kinase - - - 0.000000000000000000302 103.0
MMS2_k127_217553_0 PFAM Glycosyl transferase family 2 - - - 0.00000000002749 74.0
MMS2_k127_217553_1 phosphatidylinositol metabolic process - - - 0.00001093 58.0
MMS2_k127_2194001_0 glutamate synthase K00266,K20202 - 1.4.1.13,1.4.1.14,1.8.1.19 4.97e-223 699.0
MMS2_k127_2194001_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 572.0
MMS2_k127_2194001_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000002062 141.0
MMS2_k127_2194001_3 - - - - 0.0000000000000000000000000002739 122.0
MMS2_k127_2194001_4 - - - - 0.0000004912 59.0
MMS2_k127_2239936_0 transcription activator K06137,K20896 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 289.0
MMS2_k127_2239936_1 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647 - 2.3.3.1 0.000000000000000000000000000000000000105 145.0
MMS2_k127_2239936_2 Glycerol-3-phosphate dehydrogenase K00111 - 1.1.5.3 0.00000000000000000000000000000000002687 147.0
MMS2_k127_2239936_3 glucosylceramidase activity - - - 0.0006313 48.0
MMS2_k127_2258303_0 Type IV secretory system Conjugative DNA transfer K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 522.0
MMS2_k127_2258303_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003862 261.0
MMS2_k127_2258303_2 NurA - - - 0.00000000000000000000000000000000000000000000000000000000000000002081 236.0
MMS2_k127_2263077_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 320.0
MMS2_k127_2263077_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002455 275.0
MMS2_k127_2263077_2 3-keto-5-aminohexanoate cleavage protein K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000009584 200.0
MMS2_k127_2263077_3 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000232 199.0
MMS2_k127_2263077_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000001071 174.0
MMS2_k127_2263077_5 Major Facilitator Superfamily - - - 0.00000000000000000000000506 115.0
MMS2_k127_2263077_6 Protein conserved in bacteria - - - 0.0000001766 56.0
MMS2_k127_22643_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 319.0
MMS2_k127_22643_1 PFAM aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003584 268.0
MMS2_k127_22643_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000002121 245.0
MMS2_k127_22643_3 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000001135 244.0
MMS2_k127_2306655_0 PFAM amidohydrolase K01464,K01466 - 3.5.2.2,3.5.2.5 8.793e-200 631.0
MMS2_k127_2306655_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000004127 174.0
MMS2_k127_2306655_2 transcriptional - - - 0.0000000000000000001764 97.0
MMS2_k127_232603_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively K04076 - 3.4.21.53 1.391e-307 953.0
MMS2_k127_232603_1 succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative mitochondrial subgroup K00239,K00244 - 1.3.5.1,1.3.5.4 6.682e-195 621.0
MMS2_k127_232603_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 488.0
MMS2_k127_232603_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 402.0
MMS2_k127_232603_4 Predicted membrane protein (DUF2070) K08979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 342.0
MMS2_k127_232603_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004632 257.0
MMS2_k127_232603_6 pfkB family carbohydrate kinase K22026 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006213,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008617,GO:0008906,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009129,GO:0009130,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042278,GO:0042455,GO:0043167,GO:0043168,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046033,GO:0046035,GO:0046085,GO:0046087,GO:0046102,GO:0046128,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1905108 2.7.1.213,2.7.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000008959 246.0
MMS2_k127_232603_7 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000001867 185.0
MMS2_k127_232603_8 KEOPS complex Cgi121-like subunit K09119 - - 0.0002776 49.0
MMS2_k127_2351901_0 pathogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 371.0
MMS2_k127_2353096_0 leucyl-tRNA aminoacylation K01869 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.4 1.662e-234 749.0
MMS2_k127_2353096_1 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 363.0
MMS2_k127_2353185_0 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 494.0
MMS2_k127_2353185_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 382.0
MMS2_k127_2353185_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 301.0
MMS2_k127_2353185_3 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000001913 197.0
MMS2_k127_2353185_4 PFAM cyclase family protein K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000002444 173.0
MMS2_k127_2353185_5 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000000004996 139.0
MMS2_k127_2353185_6 Rieske-like [2Fe-2S] domain - - - 0.00000000000000000000000000000004419 127.0
MMS2_k127_2353185_7 SnoaL-like domain - - - 0.000000000000004009 80.0
MMS2_k127_2353185_8 DNA binding protein K06930 - - 0.000004904 51.0
MMS2_k127_2368076_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 387.0
MMS2_k127_2368076_1 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002597 258.0
MMS2_k127_2368076_2 - - - - 0.00000000000000000000000000000000000000006105 155.0
MMS2_k127_2420276_0 lyase activity K01714,K18127 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0008150,GO:0008152,GO:0008674,GO:0008675,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 4.1.2.51,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 317.0
MMS2_k127_2420276_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000003015 189.0
MMS2_k127_2420276_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000002389 184.0
MMS2_k127_2420276_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000001307 115.0
MMS2_k127_2420276_4 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000003151 115.0
MMS2_k127_2420276_5 Binds to the 23S rRNA K02896 - - 0.00000000000000000001155 92.0
MMS2_k127_2424520_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 367.0
MMS2_k127_2424520_1 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 319.0
MMS2_k127_2424520_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000001948 228.0
MMS2_k127_2435706_0 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000009241 171.0
MMS2_k127_2435706_1 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000003885 119.0
MMS2_k127_2435706_2 - - - - 0.000000000000000007193 83.0
MMS2_k127_2435706_3 - - - - 0.00000000000000001691 90.0
MMS2_k127_2435706_4 Prolyl oligopeptidase family K01322 - 3.4.21.26 0.00005036 45.0
MMS2_k127_2437065_0 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 467.0
MMS2_k127_2437065_1 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 413.0
MMS2_k127_2437065_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005143 280.0
MMS2_k127_2437065_3 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000008047 153.0
MMS2_k127_2437065_4 (ABC) transporter K06147 - - 0.00000000000000000000000000000000000001858 149.0
MMS2_k127_2437065_5 - - - - 0.0000008588 53.0
MMS2_k127_2440133_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000001143 177.0
MMS2_k127_2440133_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000004841 118.0
MMS2_k127_2440133_2 ABC-2 family transporter protein K01992 - - 0.0003039 53.0
MMS2_k127_2445142_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 553.0
MMS2_k127_2445142_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 519.0
MMS2_k127_2445142_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 318.0
MMS2_k127_2445142_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000004581 194.0
MMS2_k127_2445142_4 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000009739 169.0
MMS2_k127_2445142_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.000000007668 58.0
MMS2_k127_2453937_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.772e-232 723.0
MMS2_k127_2453937_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 7.164e-198 621.0
MMS2_k127_2453937_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000002576 220.0
MMS2_k127_2453937_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000006963 198.0
MMS2_k127_2459969_0 - - - - 0.000000000000000000000000000000000000000002528 179.0
MMS2_k127_2459969_1 - - - - 0.00000000000000000000000000000000000001383 149.0
MMS2_k127_2462127_0 Putative diphthamide synthesis protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 366.0
MMS2_k127_2462127_1 imidazolonepropionase activity K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003257 284.0
MMS2_k127_247072_0 inositol 2-dehydrogenase activity K19181 - 1.1.1.292 0.00000000000000000000001523 112.0
MMS2_k127_247072_1 - - - - 0.00003329 51.0
MMS2_k127_2473162_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.0 1062.0
MMS2_k127_2473162_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.06e-218 683.0
MMS2_k127_2473162_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K05308 GO:0003674,GO:0003824,GO:0008869,GO:0016829,GO:0016835,GO:0016836,GO:0047929 4.2.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 582.0
MMS2_k127_2473162_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000002443 221.0
MMS2_k127_2473162_4 V4R K07013 - - 0.000000000000000000006134 104.0
MMS2_k127_2473162_5 transcriptional regulatory protein K09714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000001813 72.0
MMS2_k127_2485593_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 452.0
MMS2_k127_2485593_1 4Fe-4S single cluster domain K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 369.0
MMS2_k127_2485593_2 Glycosyl transferase family 21 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 310.0
MMS2_k127_2485593_3 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
MMS2_k127_2485593_4 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000001784 213.0
MMS2_k127_2485593_5 - - - - 0.000000000000000000000000000000000000001336 154.0
MMS2_k127_2485593_6 molybdopterin K03635 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.000000000000000000000000000638 118.0
MMS2_k127_2485593_7 Thermopsin K01385 - 3.4.23.42 0.000000000000009685 89.0
MMS2_k127_250052_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 388.0
MMS2_k127_250052_1 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000006142 258.0
MMS2_k127_250052_2 Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids K13722 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000008538 200.0
MMS2_k127_2518546_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000009369 214.0
MMS2_k127_2518546_1 ribosomal small subunit binding - - - 0.000000000001037 70.0
MMS2_k127_2518546_2 Periplasmic copper-binding protein (NosD) - - - 0.000000001487 70.0
MMS2_k127_2524696_0 Metallopeptidase family M24 K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 456.0
MMS2_k127_2524696_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 299.0
MMS2_k127_2524696_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000005557 211.0
MMS2_k127_2524696_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000009039 201.0
MMS2_k127_2524696_4 structural constituent of ribosome K02995 - - 0.000000000000000000000000000000000000006119 148.0
MMS2_k127_2524696_5 SRP19 protein K03105 - - 0.00000000000000000002269 95.0
MMS2_k127_2526536_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 459.0
MMS2_k127_2526536_1 COG1290 Cytochrome b subunit of the bc complex K15879 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 436.0
MMS2_k127_2526536_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 359.0
MMS2_k127_2526536_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 344.0
MMS2_k127_2526536_4 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000007536 212.0
MMS2_k127_2526536_5 PFAM Rieske 2Fe-2S domain - - - 0.0000000000000000000000000000000000000000000000000000000001267 208.0
MMS2_k127_2526536_6 Protein of unknown function (DUF1634) - - - 0.00000000000000004523 85.0
MMS2_k127_2526536_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000002166 82.0
MMS2_k127_2547522_0 translation initiation factor 2 subunit alpha K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000002527 239.0
MMS2_k127_2547522_1 Binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000000003338 158.0
MMS2_k127_2547522_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000005406 147.0
MMS2_k127_2547522_3 structural constituent of ribosome K02978 - - 0.0000000000000001926 80.0
MMS2_k127_2573772_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000002758 236.0
MMS2_k127_2573772_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000003595 226.0
MMS2_k127_2573772_2 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000003867 110.0
MMS2_k127_2573772_3 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000008344 106.0
MMS2_k127_2573772_4 protein conserved in bacteria - - - 0.0000000000000000000378 94.0
MMS2_k127_258275_0 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000001189 214.0
MMS2_k127_258275_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000001362 196.0
MMS2_k127_2597822_0 Anhydro-N-acetylmuramic acid kinase K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 350.0
MMS2_k127_2597822_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002493 270.0
MMS2_k127_2597822_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
MMS2_k127_2597822_3 Peptide ABC transporter permease K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000443 233.0
MMS2_k127_2597822_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000002229 96.0
MMS2_k127_2614941_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 402.0
MMS2_k127_2614941_1 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000002032 192.0
MMS2_k127_2614941_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000142 173.0
MMS2_k127_2614941_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000006089 109.0
MMS2_k127_2628436_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 531.0
MMS2_k127_2628436_1 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000002666 247.0
MMS2_k127_2646726_0 Glycosyl transferase 4-like domain - - - 0.000000000000001885 81.0
MMS2_k127_2646726_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000004976 74.0
MMS2_k127_2674344_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000002513 194.0
MMS2_k127_2674344_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000002284 164.0
MMS2_k127_2674344_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000116 87.0
MMS2_k127_2674344_3 - - - - 0.0000005859 51.0
MMS2_k127_2686608_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1197.0
MMS2_k127_2686608_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 1.096e-229 719.0
MMS2_k127_2686608_10 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000005552 94.0
MMS2_k127_2686608_11 - - - - 0.00008326 45.0
MMS2_k127_2686608_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 531.0
MMS2_k127_2686608_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 327.0
MMS2_k127_2686608_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 333.0
MMS2_k127_2686608_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 325.0
MMS2_k127_2686608_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000007975 218.0
MMS2_k127_2686608_7 DNA binding protein K06930 - - 0.0000000000000000000000000000000000000000000000000000000001346 211.0
MMS2_k127_2686608_8 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000009014 157.0
MMS2_k127_2686608_9 Cupin domain - - - 0.00000000000000000000000000277 123.0
MMS2_k127_2731097_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382,K00383 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4,1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 408.0
MMS2_k127_2731097_1 - - - - 0.0000000000000000000000000000000000004048 142.0
MMS2_k127_2731097_2 phosphoribosylformylglycinamidine cyclo-ligase activity K01933 - 6.3.3.1 0.000000000000000000000000000000000002728 139.0
MMS2_k127_2731097_3 Protein of unknown function DUF99 K09120 - - 0.00000000000000000000000000000000003348 141.0
MMS2_k127_2731097_4 Fic/DOC family - - - 0.00000000000000000000000000000000008243 144.0
MMS2_k127_2740444_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K06976 - - 0.0000000000000000193 93.0
MMS2_k127_2745712_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 320.0
MMS2_k127_2831033_0 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000000000000000006219 254.0
MMS2_k127_2831033_1 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000000000003002 123.0
MMS2_k127_2831033_2 - - - - 0.00000000002096 68.0
MMS2_k127_2886693_0 ATPases associated with a variety of cellular activities K00400,K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 501.0
MMS2_k127_2886693_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 443.0
MMS2_k127_2886693_2 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 298.0
MMS2_k127_2886693_3 ABC transporter permease K02034 - - 0.00000000000000000000000000000000000000000000000000000000006465 215.0
MMS2_k127_2886693_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000008275 198.0
MMS2_k127_2886693_5 - - - - 0.000000000000000000000001751 109.0
MMS2_k127_2898848_0 KH domain K07041 - - 7.799e-316 976.0
MMS2_k127_2898848_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 435.0
MMS2_k127_2898848_2 1-deoxy-D-xylulose-5-phosphate synthase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 346.0
MMS2_k127_2898848_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 283.0
MMS2_k127_2898848_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000004984 214.0
MMS2_k127_2898848_5 - - - - 0.000000000000000000000000000000000000000000772 160.0
MMS2_k127_2898848_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000237 153.0
MMS2_k127_2898848_7 DNA polymerase - - - 0.0000000000000000000000000000009417 130.0
MMS2_k127_2898848_8 - - - - 0.00000000000000000000000000000554 125.0
MMS2_k127_2898848_9 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.0000000004006 61.0
MMS2_k127_2900857_0 Chromate resistance - - - 0.00000000000000000000000000000000000000000000001727 175.0
MMS2_k127_2900857_1 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000002964 143.0
MMS2_k127_2900857_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000006639 138.0
MMS2_k127_2900857_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000003953 134.0
MMS2_k127_2900857_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K00587 - 2.1.1.100 0.00000000000000000000000001292 117.0
MMS2_k127_2900857_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0002396 53.0
MMS2_k127_2916534_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 510.0
MMS2_k127_2916534_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000006782 209.0
MMS2_k127_2916534_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K12339 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000007595 203.0
MMS2_k127_2916534_3 Universal stress protein family - - - 0.000000000000000000000000000000000003766 142.0
MMS2_k127_2916534_4 - - - - 0.000000000000002668 85.0
MMS2_k127_2916534_5 structural constituent of ribosome K02962 - - 0.000000000000003576 77.0
MMS2_k127_292578_0 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001663 258.0
MMS2_k127_292578_1 SpoVT / AbrB like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
MMS2_k127_292578_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000002124 85.0
MMS2_k127_292578_3 - - - - 0.000000000000006329 84.0
MMS2_k127_2948385_0 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 387.0
MMS2_k127_2948385_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 381.0
MMS2_k127_2948385_2 peroxiredoxin activity - - - 0.00000000000000000003331 93.0
MMS2_k127_3000107_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 361.0
MMS2_k127_3000107_1 NAD-dependent epimerase dehydratase K01784,K03274 - 5.1.3.2,5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 354.0
MMS2_k127_3000107_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000007778 218.0
MMS2_k127_3000107_3 FAD dependent oxidoreductase K00244,K13796 - 1.3.5.4 0.000000000000000000000000001509 115.0
MMS2_k127_3002310_0 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 332.0
MMS2_k127_3002310_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000006127 164.0
MMS2_k127_3002310_2 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000021 157.0
MMS2_k127_3002310_3 amine dehydrogenase activity - - - 0.00000000000963 80.0
MMS2_k127_3016613_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 305.0
MMS2_k127_3016613_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000005588 220.0
MMS2_k127_3016613_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000000000005308 214.0
MMS2_k127_3016613_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000003791 186.0
MMS2_k127_3016613_4 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000000000112 175.0
MMS2_k127_3016613_5 DNA binding K06875 - - 0.00000000000000000000000000000000003231 137.0
MMS2_k127_3016613_6 Membrane protein of 12 TMs K07087 - - 0.0000000000000000000000000000000001099 151.0
MMS2_k127_3016613_7 structural constituent of ribosome K02910 - - 0.00000000000000000000000009897 108.0
MMS2_k127_3016613_8 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.0000000000000000001353 91.0
MMS2_k127_3016613_9 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.0005123 43.0
MMS2_k127_3025312_0 COG1131 ABC-type multidrug transport system, ATPase component K01990,K11050 - - 0.00000000000000000000000000000000000000000000005348 177.0
MMS2_k127_3025312_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000003781 177.0
MMS2_k127_3064343_0 Dihydrodipicolinate synthetase family K11395 - 4.1.2.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000208 259.0
MMS2_k127_3064343_1 Zinc-binding dehydrogenase K15020 - 1.3.1.84 0.00000000000000000000000000000000000000000000000000000000000004732 220.0
MMS2_k127_3064343_2 zinc-ribbon domain - - - 0.000000000000000000000000000000000000004087 154.0
MMS2_k127_3067299_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000002106 167.0
MMS2_k127_3067299_1 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000007184 135.0
MMS2_k127_3067299_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000002171 106.0
MMS2_k127_3070391_0 ATP-NAD kinase - - - 0.000000000000000000000000000000000000000000000000000000999 200.0
MMS2_k127_3070391_1 membrane-associated Zn-dependent proteases 1 - - - 0.000000000000000000000000000000000000000000000004646 187.0
MMS2_k127_3072813_0 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000003166 270.0
MMS2_k127_3072813_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000001741 244.0
MMS2_k127_3072813_2 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.00000000000000000000000000000000000000000001854 168.0
MMS2_k127_3072813_3 PFAM flavin reductase domain protein FMN-binding - - - 0.00000000000000000001696 97.0
MMS2_k127_3072813_8 Winged helix-turn-helix - - - 0.000233 51.0
MMS2_k127_3103103_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002137 288.0
MMS2_k127_3103103_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000001913 187.0
MMS2_k127_3103103_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000008676 129.0
MMS2_k127_3103103_3 DsrE/DsrF-like family - - - 0.000000000000199 74.0
MMS2_k127_3103103_4 Mediates zinc uptake. May also transport other divalent cations - - - 0.000000002733 67.0
MMS2_k127_3105476_0 Signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 290.0
MMS2_k127_3105476_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000001151 65.0
MMS2_k127_3122409_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1138.0
MMS2_k127_3122409_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 571.0
MMS2_k127_3122409_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000211 230.0
MMS2_k127_3122409_3 PRC-barrel domain - - - 0.0000000000002328 72.0
MMS2_k127_3141293_0 Amidinotransferase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 364.0
MMS2_k127_3141293_1 ThiF family K21029,K22132 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000839 194.0
MMS2_k127_3141293_2 NMD3 family K07562 - - 0.00000000000000000000000000000000000000000000405 176.0
MMS2_k127_3141293_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000001969 160.0
MMS2_k127_3141293_4 Probable molybdopterin binding domain K03638 - 2.7.7.75 0.000000000000000000000000000000000002466 143.0
MMS2_k127_3141293_5 Molybdopterin K07141 - 2.7.7.76 0.00000000000000000000000000003768 124.0
MMS2_k127_3141293_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000001102 104.0
MMS2_k127_3141293_7 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000001044 81.0
MMS2_k127_3141293_8 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000002719 67.0
MMS2_k127_3141293_9 ThiS family K03636 - - 0.000000000008008 68.0
MMS2_k127_3155880_0 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 437.0
MMS2_k127_3155880_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 430.0
MMS2_k127_3155880_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 429.0
MMS2_k127_3155880_3 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001275 249.0
MMS2_k127_3155880_4 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000001452 145.0
MMS2_k127_3155880_5 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000009456 125.0
MMS2_k127_3155880_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000001208 129.0
MMS2_k127_3155880_7 dTDP metabolic process K00943 - 2.7.4.9 0.0000000000000000000000000000001338 132.0
MMS2_k127_3155880_8 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K01580,K01634 - 4.1.1.15,4.1.2.27 0.000000000000000000000000003883 113.0
MMS2_k127_31599_0 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 381.0
MMS2_k127_31599_1 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001139 239.0
MMS2_k127_31599_2 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000001813 217.0
MMS2_k127_31599_3 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000864 214.0
MMS2_k127_31599_4 Natural resistance-associated macrophage protein - - - 0.0000000001592 63.0
MMS2_k127_31599_5 - - - - 0.0000001773 63.0
MMS2_k127_317600_0 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000000000000009164 142.0
MMS2_k127_317600_1 helix_turn_helix ASNC type K06154 - - 0.00000000000000000000000000000000006364 137.0
MMS2_k127_317600_2 - - - - 0.00000000000000000000000000005979 117.0
MMS2_k127_317600_3 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000005746 110.0
MMS2_k127_317600_4 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000002527 73.0
MMS2_k127_3177268_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 344.0
MMS2_k127_3177268_1 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000006308 229.0
MMS2_k127_3177268_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000926 214.0
MMS2_k127_3177268_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000117 154.0
MMS2_k127_3177268_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000004529 138.0
MMS2_k127_3213748_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 314.0
MMS2_k127_3213748_1 Sugar (and other) transporter K08368,K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 314.0
MMS2_k127_3213748_10 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K18816 - 2.3.1.82 0.00000245 56.0
MMS2_k127_3213748_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 301.0
MMS2_k127_3213748_3 GPR1 FUN34 yaaH family K07034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006993 248.0
MMS2_k127_3213748_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000008128 241.0
MMS2_k127_3213748_5 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000002423 192.0
MMS2_k127_3213748_6 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 4.4.1.19 0.00000000000000000000000000000000000000000001151 174.0
MMS2_k127_3213748_7 GNAT family acetyltransferase - - - 0.00000000000000000000000000000000000000000003627 168.0
MMS2_k127_3213748_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000191 115.0
MMS2_k127_3213748_9 Acetyltransferase (GNAT) domain - - - 0.0000000000003674 77.0
MMS2_k127_3244644_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 435.0
MMS2_k127_3244644_1 Calcineurin-like phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 360.0
MMS2_k127_3244644_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000001859 199.0
MMS2_k127_3244644_3 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000005485 115.0
MMS2_k127_3244644_4 NUDIX domain - - - 0.00000000000000000001057 97.0
MMS2_k127_3244644_5 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.000000000000000001033 87.0
MMS2_k127_3278612_0 Major Facilitator Superfamily - - - 3.861e-208 663.0
MMS2_k127_3278612_1 Ornithine cyclodeaminase/mu-crystallin family K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001249 287.0
MMS2_k127_3278612_2 PFAM Glycosyl transferases group 1 K19002 - 2.4.1.337 0.0000000000000000000000000000000000000000001022 174.0
MMS2_k127_3278612_3 Transcriptional regulator MarR - - - 0.00000000000000000000001239 106.0
MMS2_k127_3278612_4 - - - - 0.00000000000000000002118 93.0
MMS2_k127_3278612_5 Major facilitator superfamily - - - 0.000000000000001298 80.0
MMS2_k127_3278612_6 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000001691 52.0
MMS2_k127_3294274_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 591.0
MMS2_k127_3294274_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 577.0
MMS2_k127_3294274_2 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 317.0
MMS2_k127_3294274_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000001369 188.0
MMS2_k127_3300992_0 Related to alanyl-tRNA synthetase HxxxH domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001069 273.0
MMS2_k127_3300992_1 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000006381 91.0
MMS2_k127_3300992_2 - - - - 0.0000000000636 74.0
MMS2_k127_3304746_0 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000009273 180.0
MMS2_k127_3304746_1 transcriptional - - - 0.00000000000000000000000000000000000003604 150.0
MMS2_k127_3304746_2 SNARE associated Golgi protein - - - 0.00000000003495 65.0
MMS2_k127_3308777_0 MCM OB domain K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 369.0
MMS2_k127_3308777_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 291.0
MMS2_k127_3314605_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
MMS2_k127_3314605_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000009472 184.0
MMS2_k127_3314605_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000003275 76.0
MMS2_k127_3320276_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000004118 199.0
MMS2_k127_3320276_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000005289 161.0
MMS2_k127_3320276_2 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000000000001094 102.0
MMS2_k127_3320276_3 Glycosyl transferase family 21 K00786 - - 0.00000000000000000000002404 104.0
MMS2_k127_3320276_4 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000000001377 96.0
MMS2_k127_3330023_0 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000005049 238.0
MMS2_k127_3330023_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000001804 190.0
MMS2_k127_3358187_0 TopoisomeraseII K02470 - 5.99.1.3 7.345e-280 872.0
MMS2_k127_3358187_1 DNA Topoisomerase IV K02469 - 5.99.1.3 1.231e-272 860.0
MMS2_k127_3358187_2 Aminotransferase class-III K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 613.0
MMS2_k127_3358187_3 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 453.0
MMS2_k127_3358187_4 acetamidase formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 313.0
MMS2_k127_3358187_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007152 255.0
MMS2_k127_3358187_6 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001416 216.0
MMS2_k127_3358187_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000116 215.0
MMS2_k127_3358187_8 - - - - 0.0000000000000000000000003685 106.0
MMS2_k127_3358187_9 small metal-binding protein - - - 0.0000000003321 64.0
MMS2_k127_3360150_0 DEAD/H associated K03724 - - 0.00000000000000000000000000000000001088 151.0
MMS2_k127_3360150_1 Transcriptional regulator, ArsR family - - - 0.00000000000000003541 87.0
MMS2_k127_3370974_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 310.0
MMS2_k127_3370974_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000008944 201.0
MMS2_k127_3370974_2 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000000002966 78.0
MMS2_k127_3393487_0 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 467.0
MMS2_k127_3393487_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 389.0
MMS2_k127_3393487_2 PFAM CBS domain K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 371.0
MMS2_k127_3393487_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001218 239.0
MMS2_k127_3393487_4 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
MMS2_k127_3393487_5 Iron dependent repressor, metal binding and dimerisation domain - - - 0.0000000000000000000000000000000000461 138.0
MMS2_k127_3393487_6 Acetyltransferase (GNAT) domain - - - 0.00000000002355 71.0
MMS2_k127_3404099_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 369.0
MMS2_k127_3404099_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000001078 243.0
MMS2_k127_3404099_2 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000000000007508 99.0
MMS2_k127_3404099_3 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000007655 64.0
MMS2_k127_3410914_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 6.941e-247 772.0
MMS2_k127_3410914_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 240.0
MMS2_k127_3410914_2 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000001334 136.0
MMS2_k127_3410914_3 Protein of unknown function (DUF1641) - - - 0.0000000000000000006842 92.0
MMS2_k127_3410914_4 Molybdenum cofactor synthesis domain protein K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.0001677 48.0
MMS2_k127_342105_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 548.0
MMS2_k127_342105_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 301.0
MMS2_k127_342105_2 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000001287 199.0
MMS2_k127_342105_3 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000001345 177.0
MMS2_k127_342105_4 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000000000000003561 149.0
MMS2_k127_3447557_0 Enoyl-CoA hydratase/isomerase K15016 - 1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 385.0
MMS2_k127_3447557_1 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 317.0
MMS2_k127_3447557_2 Threonyl and Alanyl tRNA synthetase second additional domain K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 254.0
MMS2_k127_3447557_3 Metallo-beta-lactamase domain protein - - - 0.000000000000000000000000000000000005652 144.0
MMS2_k127_3447557_4 sterol carrier protein - - - 0.0000000001089 66.0
MMS2_k127_3451186_0 isoprenoid metabolic process K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002179 289.0
MMS2_k127_3451186_1 AAA domain K18690 GO:0003674,GO:0003824,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576 2.7.1.186 0.00000000000000000000000000000000000000000000005974 175.0
MMS2_k127_3451186_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000002965 116.0
MMS2_k127_3451186_3 Isochorismatase family - - - 0.00000000002683 67.0
MMS2_k127_3451186_4 HNH endonuclease K07451 - - 0.0000003401 60.0
MMS2_k127_3472922_0 AAA domain K18690 GO:0003674,GO:0003824,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576 2.7.1.186 0.000000000000000000000000000000000000000000000000000009523 196.0
MMS2_k127_3472922_1 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000747 134.0
MMS2_k127_3472922_2 Domain of unknown function DUF302 - - - 0.00000000000000000000000000002243 121.0
MMS2_k127_3472922_3 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000005485 113.0
MMS2_k127_3472922_4 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000001468 102.0
MMS2_k127_3472922_5 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.000000000004794 68.0
MMS2_k127_3479090_0 Pfam:KH_3 K06865 - - 7.072e-219 690.0
MMS2_k127_3479090_1 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 462.0
MMS2_k127_3479090_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 378.0
MMS2_k127_3479090_3 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000001048 197.0
MMS2_k127_351541_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1031.0
MMS2_k127_351541_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.485e-232 726.0
MMS2_k127_351541_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000002136 166.0
MMS2_k127_3520107_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 7.175e-225 706.0
MMS2_k127_3520107_1 Fumarase C C-terminus K01679 - 4.2.1.2 1.395e-199 630.0
MMS2_k127_3520107_2 Uncharacterized protein family UPF0004 K15865 - 2.8.4.5 0.00000000000000000000000000000235 122.0
MMS2_k127_3534503_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 524.0
MMS2_k127_3534503_1 Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002088 263.0
MMS2_k127_3542614_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002157 281.0
MMS2_k127_3542614_1 SnoaL-like domain - - - 0.00000000000000000000000000002112 127.0
MMS2_k127_3542614_2 Acetyltransferase (GNAT) domain - - - 0.00004682 47.0
MMS2_k127_3554391_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.0 1247.0
MMS2_k127_3554391_1 PilT protein domain protein - - - 0.00000000000000000000000004482 113.0
MMS2_k127_3554391_2 - - - - 0.0000000000000000533 83.0
MMS2_k127_3554391_3 FAD dependent oxidoreductase - - - 0.0000000000000001391 80.0
MMS2_k127_3575324_0 Enoyl-CoA hydratase/isomerase K15016 - 1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 344.0
MMS2_k127_3575324_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001819 258.0
MMS2_k127_3575324_2 ABC-2 family transporter protein K01992 - - 0.000000004216 69.0
MMS2_k127_3588797_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 497.0
MMS2_k127_3588797_1 ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 405.0
MMS2_k127_3588797_2 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 340.0
MMS2_k127_3588797_3 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 303.0
MMS2_k127_3588797_4 - - - - 0.00000000000000003777 92.0
MMS2_k127_3588797_5 - - - - 0.000000002796 64.0
MMS2_k127_3593112_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008219 258.0
MMS2_k127_3593112_1 - - - - 0.0000000000000000000000000000000000000000001812 166.0
MMS2_k127_3593112_2 protein conserved in archaea K09746 - - 0.0000000000000000000000001425 109.0
MMS2_k127_3593112_3 Beta-Casp domain K07577 - - 0.00000000000008635 71.0
MMS2_k127_3630481_0 Quinolinate phosphoribosyl transferase, C-terminal domain K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 454.0
MMS2_k127_3630481_1 cysteine-tRNA ligase activity K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000002213 183.0
MMS2_k127_3630481_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.000000000000000000000000000000002235 135.0
MMS2_k127_3630481_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000006333 83.0
MMS2_k127_3635437_0 Proton-conducting membrane transporter K00342,K22168 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 450.0
MMS2_k127_3635437_1 Proton-conducting membrane transporter K00343,K22169 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 445.0
MMS2_k127_3635437_2 - - - - 0.0000000000000000000001496 98.0
MMS2_k127_3635437_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000003023 83.0
MMS2_k127_3635437_4 - - - - 0.00000000001467 69.0
MMS2_k127_3648615_0 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 304.0
MMS2_k127_3648615_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000001422 137.0
MMS2_k127_367671_0 helicase superfamily c-terminal domain K03724 - - 0.0 1052.0
MMS2_k127_367671_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.046e-237 754.0
MMS2_k127_367671_2 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 317.0
MMS2_k127_367671_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000923 293.0
MMS2_k127_367671_4 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 267.0
MMS2_k127_367671_5 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000719 240.0
MMS2_k127_367671_6 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000000000000000000007796 174.0
MMS2_k127_367671_7 Belongs to the UPF0292 family - - - 0.000000000000000000000004404 105.0
MMS2_k127_367671_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000001156 71.0
MMS2_k127_3683344_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431,K10536 - 3.5.1.6,3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 390.0
MMS2_k127_3683344_1 TIGRFAM dihydroorotate dehydrogenase family protein K17723 - 1.3.1.1 0.0000000000000000000000000000000799 127.0
MMS2_k127_3683344_2 Hsp20/alpha crystallin family - - - 0.0005787 45.0
MMS2_k127_3697599_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000002735 200.0
MMS2_k127_3697599_1 BadF/BadG/BcrA/BcrD ATPase family K00884 - 2.7.1.59 0.00000000000000000000000000000000005818 147.0
MMS2_k127_3721224_0 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 371.0
MMS2_k127_3721224_1 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000001223 171.0
MMS2_k127_3721224_2 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000004986 170.0
MMS2_k127_3721224_3 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000001497 163.0
MMS2_k127_3721224_4 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000002693 150.0
MMS2_k127_3722461_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 7.317e-205 647.0
MMS2_k127_3722461_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 471.0
MMS2_k127_3722461_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000005223 145.0
MMS2_k127_3722461_3 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000003538 141.0
MMS2_k127_3722461_4 protein conserved in archaea K09746 - - 0.00000000000001376 77.0
MMS2_k127_3740526_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 302.0
MMS2_k127_3740526_1 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000000000000000000000000005402 169.0
MMS2_k127_3740526_2 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000005864 133.0
MMS2_k127_3754229_0 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 448.0
MMS2_k127_3754229_1 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 410.0
MMS2_k127_3754229_2 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002942 269.0
MMS2_k127_3754229_3 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000008797 117.0
MMS2_k127_3754229_4 FR47-like protein - - - 0.000002243 56.0
MMS2_k127_3763352_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 448.0
MMS2_k127_3763352_1 PFAM Thiolase K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 393.0
MMS2_k127_3763352_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000134 172.0
MMS2_k127_3763352_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000001313 132.0
MMS2_k127_3763352_4 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000008906 91.0
MMS2_k127_3763352_5 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000001211 78.0
MMS2_k127_3763352_6 nucleic-acid-binding protein containing a Zn-ribbon K00074,K07068 - 1.1.1.157 0.0000000006005 64.0
MMS2_k127_3765423_0 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 295.0
MMS2_k127_3765423_1 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000197 123.0
MMS2_k127_3765423_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000005534 86.0
MMS2_k127_3777295_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 518.0
MMS2_k127_3777295_1 Removes the phosphate from trehalose 6-phosphate K01087 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.12 0.0000000000000000000000000000000000000000000000000005509 192.0
MMS2_k127_3777295_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K18540 - 3.5.1.100 0.000000000000000000000000002596 114.0
MMS2_k127_3777988_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 296.0
MMS2_k127_3777988_1 - - - - 0.000000000000000000000000000000007735 144.0
MMS2_k127_3777988_2 Thioesterase superfamily - - - 0.00000000000000008124 85.0
MMS2_k127_3777988_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000004256 73.0
MMS2_k127_3777988_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0009819 49.0
MMS2_k127_377852_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 583.0
MMS2_k127_377852_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 563.0
MMS2_k127_377852_2 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 425.0
MMS2_k127_377852_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 348.0
MMS2_k127_377852_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 324.0
MMS2_k127_377852_5 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000006129 239.0
MMS2_k127_377852_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000002259 171.0
MMS2_k127_377852_7 KR domain - - - 0.000000000000000000000000001242 121.0
MMS2_k127_377852_8 Acetyltransferase (GNAT) domain - - - 0.000000001203 66.0
MMS2_k127_377852_9 - - - - 0.00000000134 60.0
MMS2_k127_3780865_0 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 362.0
MMS2_k127_3780865_1 ATPases associated with a variety of cellular activities K17314 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 297.0
MMS2_k127_3780865_2 Binding-protein-dependent transport system inner membrane component K17313 - - 0.00000000000000000000000000000000000000000000000000000000000000005643 231.0
MMS2_k127_3780865_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000001853 86.0
MMS2_k127_3780865_4 Binding-protein-dependent transport system inner membrane component K17312 - - 0.00000000005006 72.0
MMS2_k127_3811121_0 COG4608 ABC-type oligopeptide transport system, ATPase component K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 520.0
MMS2_k127_3811121_1 COG0444 ABC-type dipeptide oligopeptide nickel transport system ATPase component K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 515.0
MMS2_k127_3811121_10 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000007444 254.0
MMS2_k127_3811121_11 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000000006769 181.0
MMS2_k127_3811121_12 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000009519 135.0
MMS2_k127_3811121_13 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity) K01170 - 4.6.1.16 0.0000000000000000000000001369 118.0
MMS2_k127_3811121_14 retrograde vesicle-mediated transport, Golgi to ER - - - 0.0000979 51.0
MMS2_k127_3811121_2 Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 484.0
MMS2_k127_3811121_3 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 404.0
MMS2_k127_3811121_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 368.0
MMS2_k127_3811121_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 361.0
MMS2_k127_3811121_6 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 342.0
MMS2_k127_3811121_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 334.0
MMS2_k127_3811121_8 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 332.0
MMS2_k127_3811121_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 313.0
MMS2_k127_381667_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 516.0
MMS2_k127_381667_1 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 471.0
MMS2_k127_381667_2 N-terminal TM domain of oligopeptide transport permease C - - - 0.000000000000000000000000000000000000000000000000009263 188.0
MMS2_k127_381667_3 TCP-1/cpn60 chaperonin family K22447 - - 0.000000000000000006146 85.0
MMS2_k127_3859971_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 394.0
MMS2_k127_3859971_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000006053 258.0
MMS2_k127_3859971_2 Met-10+ like-protein K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000007527 216.0
MMS2_k127_3859971_3 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000005733 138.0
MMS2_k127_3859971_4 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000001745 64.0
MMS2_k127_3859971_5 phenylalanine-tRNA ligase activity K01890 - 6.1.1.20 0.00000002429 57.0
MMS2_k127_3863614_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 2.947e-261 825.0
MMS2_k127_3863614_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 396.0
MMS2_k127_3863614_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000001964 62.0
MMS2_k127_3896411_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 354.0
MMS2_k127_3896411_1 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000008159 267.0
MMS2_k127_3896411_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000001714 211.0
MMS2_k127_3896411_3 Protein of unknown function (DUF1641) - - - 0.000000000000000006006 89.0
MMS2_k127_3906721_0 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003571 281.0
MMS2_k127_3906721_1 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000002802 204.0
MMS2_k127_3928822_0 PFAM phosphatidate cytidylyltransferase - - - 0.0000000000000000000000000007921 124.0
MMS2_k127_3928822_1 FR47-like protein - - - 0.000000000000000000000000003384 123.0
MMS2_k127_4047748_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 594.0
MMS2_k127_4047748_1 Citrate transporter K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 357.0
MMS2_k127_4054576_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004772 273.0
MMS2_k127_4054576_1 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000135 213.0
MMS2_k127_4054576_2 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000007103 121.0
MMS2_k127_4054576_3 collagen metabolic process K08677 - - 0.0000000000000009869 84.0
MMS2_k127_4060329_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 290.0
MMS2_k127_4060329_1 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000006969 198.0
MMS2_k127_4063957_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 535.0
MMS2_k127_4063957_1 4-hydroxy-tetrahydrodipicolinate reductase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 444.0
MMS2_k127_4063957_2 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000003358 193.0
MMS2_k127_4063957_3 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000000001859 174.0
MMS2_k127_4141096_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 608.0
MMS2_k127_4141096_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000001059 179.0
MMS2_k127_4141096_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000002077 145.0
MMS2_k127_4142694_0 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 8.525e-234 738.0
MMS2_k127_4142694_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 7.523e-200 640.0
MMS2_k127_4142694_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000004847 221.0
MMS2_k127_4142694_3 GHMP kinases N terminal domain K00891 - 2.7.1.71 0.000000000000000000000000000000000000000002414 162.0
MMS2_k127_4142694_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000005721 126.0
MMS2_k127_4195132_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 3.829e-253 795.0
MMS2_k127_4195132_1 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 460.0
MMS2_k127_4195132_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 377.0
MMS2_k127_4195132_3 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000002981 235.0
MMS2_k127_4195132_4 adenyl ribonucleotide binding - - - 0.00000000000000000000000000000000000000000000000000861 184.0
MMS2_k127_4195132_5 LysE type translocator - - - 0.00000000000000000000000001875 115.0
MMS2_k127_4199826_0 Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids K13722 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 627.0
MMS2_k127_4199826_1 DNA polymerase type-B family K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 591.0
MMS2_k127_4199826_2 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 358.0
MMS2_k127_4199826_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 309.0
MMS2_k127_4199826_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000004577 239.0
MMS2_k127_4199826_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000178 218.0
MMS2_k127_4208569_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008649 532.0
MMS2_k127_423392_0 Type II/IV secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 445.0
MMS2_k127_423392_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002192 273.0
MMS2_k127_423392_2 Type II secretion system K07333 - - 0.00000000000000000000000006002 113.0
MMS2_k127_4257878_0 threonyl-tRNA aminoacylation K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 472.0
MMS2_k127_4257878_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 464.0
MMS2_k127_4257878_2 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 399.0
MMS2_k127_4257878_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 347.0
MMS2_k127_4257878_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 297.0
MMS2_k127_4257878_5 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005188 269.0
MMS2_k127_4257878_6 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity) K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000155 260.0
MMS2_k127_4257878_7 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000006553 177.0
MMS2_k127_4257878_8 - - - - 0.0000000002467 64.0
MMS2_k127_4257878_9 AAA-like domain K06915 - - 0.00000003136 59.0
MMS2_k127_4259357_0 4Fe-4S single cluster domain K06937 - - 1.206e-306 943.0
MMS2_k127_4259357_1 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000002748 259.0
MMS2_k127_4259357_2 leucyl-tRNA aminoacylation K01869 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.4 0.000000000000000000000000000000000000000000000001439 175.0
MMS2_k127_4259357_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity) - - - 0.0000000003037 66.0
MMS2_k127_4266498_0 V-type ATPase 116kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 530.0
MMS2_k127_4266498_1 DNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 304.0
MMS2_k127_4266498_2 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000008469 164.0
MMS2_k127_4266498_3 - - - - 0.000000000000004773 83.0
MMS2_k127_4266498_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000001689 74.0
MMS2_k127_4266498_5 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000001021 57.0
MMS2_k127_4282734_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000004846 160.0
MMS2_k127_4282734_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79,1.2.1.8 0.0000000000000000000000000000000001517 134.0
MMS2_k127_4282734_2 Methyltransferase type 11 - - - 0.00000000000000000000000003291 115.0
MMS2_k127_4316628_0 acyl-CoA dehydrogenase K18244 - - 0.00000000000000000000000000000000000000000000000007472 192.0
MMS2_k127_4316628_1 - - - - 0.0000000000000001344 91.0
MMS2_k127_432464_0 HELICc2 K10844 - 3.6.4.12 3.307e-194 623.0
MMS2_k127_432464_1 DNA-binding transcription factor activity K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000299 231.0
MMS2_k127_432464_2 - K07103 - - 0.00000000000000000000000000000000000000001641 159.0
MMS2_k127_432464_3 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00001551 48.0
MMS2_k127_432464_4 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0001614 44.0
MMS2_k127_4335356_0 MOFRL family K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001248 280.0
MMS2_k127_4335356_1 Isopentenyl-diphosphate delta-isomerase K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000001092 199.0
MMS2_k127_4335356_2 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000008303 179.0
MMS2_k127_4335356_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000005351 94.0
MMS2_k127_4343895_0 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000004113 177.0
MMS2_k127_4343895_1 - - - - 0.0000000000000000000000001865 107.0
MMS2_k127_4343895_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000003466 95.0
MMS2_k127_4343895_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00007543 51.0
MMS2_k127_4377862_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1178.0
MMS2_k127_4377862_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 578.0
MMS2_k127_4377862_2 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000000000000001148 195.0
MMS2_k127_4384150_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 416.0
MMS2_k127_4384150_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 321.0
MMS2_k127_4384150_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000002473 243.0
MMS2_k127_4397517_0 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000326 251.0
MMS2_k127_4397517_1 SMART PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000342 194.0
MMS2_k127_4397517_2 ZPR1 zinc-finger domain K06874 - - 0.0000000000000000000000000000000000000007906 154.0
MMS2_k127_4397517_3 Acetyltransferase GNAT family - - - 0.000000000000000004201 88.0
MMS2_k127_4399210_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 409.0
MMS2_k127_4399210_1 FAD dependent oxidoreductase K13796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 295.0
MMS2_k127_4399210_2 Belongs to the TPP enzyme family K03852 - 2.3.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000036 285.0
MMS2_k127_4399210_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000002707 219.0
MMS2_k127_4399210_4 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000002333 140.0
MMS2_k127_4401403_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000004476 213.0
MMS2_k127_4401403_1 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000000000000000000000008238 163.0
MMS2_k127_4412489_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1326.0
MMS2_k127_4412489_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.542e-206 655.0
MMS2_k127_4412489_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 470.0
MMS2_k127_4412489_3 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 424.0
MMS2_k127_4412489_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 314.0
MMS2_k127_4412489_5 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000001622 242.0
MMS2_k127_4412489_6 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
MMS2_k127_4412489_7 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000001244 176.0
MMS2_k127_4412489_8 SCP-2 sterol transfer family - - - 0.0000000000000000000000000006116 115.0
MMS2_k127_4418328_0 Pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 294.0
MMS2_k127_4418328_1 Cobalamin adenosyltransferase - - - 0.00000000000000000000000000000000000000000000000000001403 194.0
MMS2_k127_4418328_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000004597 119.0
MMS2_k127_4422169_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 2.059e-229 726.0
MMS2_k127_4422169_1 tripeptidyl-peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 415.0
MMS2_k127_4422169_10 Major Facilitator Superfamily - - - 0.000000000000000004086 97.0
MMS2_k127_4422169_11 SpoVT / AbrB like domain - - - 0.000000000000001707 79.0
MMS2_k127_4422169_12 parallel beta-helix repeat - - - 0.00002656 59.0
MMS2_k127_4422169_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 324.0
MMS2_k127_4422169_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 318.0
MMS2_k127_4422169_4 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000002462 220.0
MMS2_k127_4422169_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000827 181.0
MMS2_k127_4422169_6 Cleaves H-Pro-AMC as well as a wide spectrum of amino acid substrates and several peptide substrates without a proline at the N-terminus K01259 - 3.4.11.5 0.0000000000000000000000000000000008248 134.0
MMS2_k127_4422169_7 Domain of unknown function DUF302 - - - 0.00000000000000000000000000009347 121.0
MMS2_k127_4422169_8 Uncharacterized protein conserved in archaea (DUF2175) - - - 0.00000000000000000000000001655 111.0
MMS2_k127_4422169_9 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000002807 103.0
MMS2_k127_4454015_0 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007191 266.0
MMS2_k127_4454015_1 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000407 147.0
MMS2_k127_4454015_2 DUF218 domain - - - 0.00000000006279 69.0
MMS2_k127_4454015_3 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0006373 44.0
MMS2_k127_4485404_0 RibD C-terminal domain - - - 0.000000000000000000001571 102.0
MMS2_k127_4485404_1 Phosphoglycerate mutase K01834 - 5.4.2.11 0.0000000001249 63.0
MMS2_k127_4535412_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 1.05e-225 729.0
MMS2_k127_4535412_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 354.0
MMS2_k127_4535412_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001336 261.0
MMS2_k127_4579464_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007268 284.0
MMS2_k127_4579464_1 - - - - 0.000000248 53.0
MMS2_k127_4586820_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 430.0
MMS2_k127_4586820_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000001597 98.0
MMS2_k127_4613760_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001843 257.0
MMS2_k127_4613760_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000004858 167.0
MMS2_k127_4627743_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002899 248.0
MMS2_k127_4627743_1 DsrE/DsrF-like family - - - 0.000000001432 63.0
MMS2_k127_4629005_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 476.0
MMS2_k127_4629005_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000001299 190.0
MMS2_k127_4629005_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000009683 98.0
MMS2_k127_4629005_3 Protein of unknown function (DUF1641) - - - 0.0002185 50.0
MMS2_k127_465603_0 MmgE/PrpD family K01720 - 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 465.0
MMS2_k127_465603_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 332.0
MMS2_k127_465603_2 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000000000000000001505 167.0
MMS2_k127_465603_3 Domain of unknown function (DUF389) - - - 0.00000000000000000004704 102.0
MMS2_k127_465603_4 TspO/MBR family K05770 - - 0.0000000001558 63.0
MMS2_k127_4662151_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 288.0
MMS2_k127_4662151_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000002155 227.0
MMS2_k127_4662151_2 protein serine/threonine phosphatase activity - - - 0.00000000000000024 89.0
MMS2_k127_4681721_0 Glycosyltransferase like family 2 - - - 0.0000000000000001415 88.0
MMS2_k127_4681721_1 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00005921 54.0
MMS2_k127_4681721_2 Methyltransferase domain - - - 0.0005947 51.0
MMS2_k127_4704084_0 ATPase domain predominantly from Archaea K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 355.0
MMS2_k127_4704084_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000003313 214.0
MMS2_k127_4704084_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000001163 156.0
MMS2_k127_4744347_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 517.0
MMS2_k127_4744347_1 Transcriptional regulator - - - 0.000003116 54.0
MMS2_k127_4745648_0 Hydroxymethylglutaryl-coenzyme A reductase K00021,K00054 - 1.1.1.34,1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 515.0
MMS2_k127_4745648_1 aspartate carbamoyltransferase activity K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 388.0
MMS2_k127_4745648_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000005883 263.0
MMS2_k127_4745648_3 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000000000000000008865 204.0
MMS2_k127_4745648_4 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000000000000000008806 138.0
MMS2_k127_4745648_5 tetratricopeptide - - - 0.0000000000000000000000000000000003327 140.0
MMS2_k127_4745648_6 - - - - 0.00000000000001051 79.0
MMS2_k127_4745648_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000001928 64.0
MMS2_k127_4754610_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 532.0
MMS2_k127_4754610_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836 - 2.6.1.19,2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 369.0
MMS2_k127_4754610_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 296.0
MMS2_k127_4754610_3 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000007669 153.0
MMS2_k127_4754610_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000004178 105.0
MMS2_k127_4801930_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000001081 188.0
MMS2_k127_4801930_1 Pro-kumamolisin, activation domain - - - 0.00000000000000000000000000000000000000000003665 184.0
MMS2_k127_4801930_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000009116 124.0
MMS2_k127_4801930_3 Evidence 4 Homologs of previously reported genes of K07145,K21481 - 1.14.99.48,1.14.99.57 0.00000000000000000000009296 100.0
MMS2_k127_4825321_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 295.0
MMS2_k127_4825321_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001923 264.0
MMS2_k127_4825321_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000008876 150.0
MMS2_k127_4825321_3 Saccharopine dehydrogenase K00290,K19064 - 1.4.1.18,1.5.1.7 0.000000000000003157 80.0
MMS2_k127_482603_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 1.01e-244 768.0
MMS2_k127_482603_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 560.0
MMS2_k127_482603_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 445.0
MMS2_k127_482603_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009423 256.0
MMS2_k127_482603_4 - - - - 0.0000000000000000000000000000805 116.0
MMS2_k127_482603_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 - 1.1.1.29 0.0000000004444 65.0
MMS2_k127_4849290_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.301e-319 994.0
MMS2_k127_4849290_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 411.0
MMS2_k127_4849290_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002649 244.0
MMS2_k127_4849290_3 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000008162 180.0
MMS2_k127_4849290_4 HTH DNA binding domain K06930 - - 0.0000000000000000000000000002004 122.0
MMS2_k127_4860810_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 603.0
MMS2_k127_4860810_1 Histidine kinase - - - 0.00002707 56.0
MMS2_k127_4881218_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 587.0
MMS2_k127_4881218_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 363.0
MMS2_k127_4881218_2 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000002667 156.0
MMS2_k127_4881218_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000001347 149.0
MMS2_k127_4881218_4 - - - - 0.000000000000000000002787 106.0
MMS2_k127_4881218_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000006372 78.0
MMS2_k127_4881218_6 - - - - 0.0000004479 58.0
MMS2_k127_4881218_7 - - - - 0.00001386 53.0
MMS2_k127_4884567_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 607.0
MMS2_k127_4884567_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 518.0
MMS2_k127_4884567_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009486,GO:0009987,GO:0015002,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000004477 259.0
MMS2_k127_4884567_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000071 147.0
MMS2_k127_4884567_4 Cytochrome C oxidase subunit II K02275,K02826 - 1.10.3.12,1.9.3.1 0.00000000000001097 79.0
MMS2_k127_4885073_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 6.784e-197 620.0
MMS2_k127_4885073_1 Sugar (and other) transporter K08176 - - 1.751e-194 618.0
MMS2_k127_4885073_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 472.0
MMS2_k127_4885073_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 451.0
MMS2_k127_4885073_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 274.0
MMS2_k127_4885073_5 Presenilin, signal peptide peptidase, family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001207 250.0
MMS2_k127_4885073_6 acylphosphatase activity K01512 - 3.6.1.7 0.0000000000000000002923 90.0
MMS2_k127_4886553_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 4.649e-195 617.0
MMS2_k127_4886553_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 442.0
MMS2_k127_4886553_10 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 310.0
MMS2_k127_4886553_11 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002145 274.0
MMS2_k127_4886553_12 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000000001088 241.0
MMS2_k127_4886553_13 Archaeal holliday junction resolvase (hjc) - - - 0.000000000000000000000000000000000000000000000000000001771 198.0
MMS2_k127_4886553_14 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000001337 194.0
MMS2_k127_4886553_15 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000005736 181.0
MMS2_k127_4886553_16 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000543 179.0
MMS2_k127_4886553_17 Binds to the 23S rRNA K02921 - - 0.00000000000000000000000000000000001071 136.0
MMS2_k127_4886553_18 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000000000009968 129.0
MMS2_k127_4886553_19 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000001029 126.0
MMS2_k127_4886553_2 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 386.0
MMS2_k127_4886553_20 RNA polymerase K03051 - 2.7.7.6 0.00000000000003779 76.0
MMS2_k127_4886553_21 Belongs to the aldehyde dehydrogenase family K00131 - 1.2.1.9 0.00000004077 65.0
MMS2_k127_4886553_3 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 362.0
MMS2_k127_4886553_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 355.0
MMS2_k127_4886553_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 355.0
MMS2_k127_4886553_6 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 349.0
MMS2_k127_4886553_7 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 343.0
MMS2_k127_4886553_8 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 324.0
MMS2_k127_4886553_9 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 299.0
MMS2_k127_4948291_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 471.0
MMS2_k127_4948291_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 343.0
MMS2_k127_4948291_10 regulation of RNA biosynthetic process - - - 0.0000000000000366 77.0
MMS2_k127_4948291_2 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000418 251.0
MMS2_k127_4948291_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000004237 223.0
MMS2_k127_4948291_4 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000001526 169.0
MMS2_k127_4948291_5 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000001811 131.0
MMS2_k127_4948291_6 ABC-2 type transporter K01992 - - 0.0000000000000000000000000004625 123.0
MMS2_k127_4948291_7 ABC-2 type transporter K01992 - - 0.0000000000000000000000006196 114.0
MMS2_k127_4948291_8 Lrp/AsnC ligand binding domain - - - 0.0000000000000000001012 90.0
MMS2_k127_4948291_9 -acetyltransferase - - - 0.0000000000000000696 82.0
MMS2_k127_4950636_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 566.0
MMS2_k127_4950636_1 COG1472 Beta-glucosidase-related glycosidases K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 324.0
MMS2_k127_4950636_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000002998 226.0
MMS2_k127_4950636_3 FR47-like protein - - - 0.00000000263 67.0
MMS2_k127_4965498_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 4.32e-205 650.0
MMS2_k127_4965498_1 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 303.0
MMS2_k127_4965498_2 Subtilase family - - - 0.0000000000000000000000000000000000000001213 171.0
MMS2_k127_4984059_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 375.0
MMS2_k127_4984059_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 362.0
MMS2_k127_4984059_2 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 254.0
MMS2_k127_4984059_3 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000001022 141.0
MMS2_k127_4984059_4 Winged helix DNA-binding domain - - - 0.0000000000000000007575 99.0
MMS2_k127_4984059_5 - - - - 0.0001027 53.0
MMS2_k127_5002155_0 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 295.0
MMS2_k127_5002155_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006892 241.0
MMS2_k127_5002155_2 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000000000001046 92.0
MMS2_k127_5016722_0 Uncharacterized protein family (UPF0051) K09014 - - 8.495e-250 777.0
MMS2_k127_5016722_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 312.0
MMS2_k127_5016722_2 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003339 276.0
MMS2_k127_5016722_3 ATPases associated with a variety of cellular activities K09013 - - 0.00000000000000000000000000000000000000000000000000004681 188.0
MMS2_k127_5022663_0 - - - - 0.000000000001675 71.0
MMS2_k127_518383_0 NMD3 family K07562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000498 246.0
MMS2_k127_518383_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000000000000000000000000002452 143.0
MMS2_k127_518383_2 Amidinotransferase K01478 - 3.5.3.6 0.0000000003413 61.0
MMS2_k127_532834_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 3.798e-200 637.0
MMS2_k127_532834_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 517.0
MMS2_k127_532834_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002229 281.0
MMS2_k127_532834_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000001022 189.0
MMS2_k127_543337_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000001491 124.0
MMS2_k127_543337_1 NlpC/P60 family - - - 0.0000000184 59.0
MMS2_k127_543337_2 N-acetylglucosamine-6-phosphate deacetylase K01443 - 3.5.1.25 0.0001742 47.0
MMS2_k127_548276_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000009059 136.0
MMS2_k127_548276_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000002625 103.0
MMS2_k127_548276_2 FUN14 family - - - 0.000000000003413 70.0
MMS2_k127_559343_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001966 238.0
MMS2_k127_559343_1 alcohol dehydrogenase K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000002213 203.0
MMS2_k127_559343_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000005422 172.0
MMS2_k127_559343_3 CRISPR-associated protein Cas4 K07464 GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0032392,GO:0032508,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0048037,GO:0051276,GO:0051536,GO:0051537,GO:0051540,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.12.1 0.000000000000000008473 93.0
MMS2_k127_569390_0 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003047 224.0
MMS2_k127_569390_1 - - - - 0.0000000000000000000000000000000000000000000000000000002395 212.0
MMS2_k127_569390_2 COG1290 Cytochrome b subunit of the bc complex K15879 - - 0.00001148 53.0
MMS2_k127_569572_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 428.0
MMS2_k127_575439_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 398.0
MMS2_k127_575439_1 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000000005762 136.0
MMS2_k127_575439_2 Protein of unknown function (DUF3198) - - - 0.000000000007884 68.0
MMS2_k127_614097_0 PFAM NAD-dependent epimerase dehydratase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000001808 243.0
MMS2_k127_614097_1 PFAM binding-protein-dependent transport systems inner membrane component K15496 - - 0.00000000000000000000000000000000000000000000000000000000000003477 222.0
MMS2_k127_614097_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.00000000000000000000000000000000000007517 146.0
MMS2_k127_614097_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000002909 70.0
MMS2_k127_614097_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000131 75.0
MMS2_k127_620372_0 Pro-kumamolisin, activation domain - - - 0.00000000000000000000000000000000000000000000000000000000000006897 244.0
MMS2_k127_620372_1 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000002114 200.0
MMS2_k127_620372_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000001578 203.0
MMS2_k127_620372_3 acetyltransferase - - - 0.0000000000000000000000000007236 118.0
MMS2_k127_620372_4 - K01385 - 3.4.23.42 0.000000000000001297 92.0
MMS2_k127_620372_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000002456 66.0
MMS2_k127_620372_7 - K02928 - - 0.0006651 42.0
MMS2_k127_652735_0 Aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 404.0
MMS2_k127_652735_1 Protein of unknown function (DUF1697) - - - 0.0000000000000006994 80.0
MMS2_k127_693203_0 NADP-dependent dehydrogenase of the nED (non- phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D- glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3- phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes K18128 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006081,GO:0006082,GO:0006090,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009255,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016620,GO:0016903,GO:0019637,GO:0019682,GO:0019752,GO:0022607,GO:0032787,GO:0042802,GO:0042803,GO:0043436,GO:0043796,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0061678,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901575 1.2.1.89 2.492e-196 619.0
MMS2_k127_693203_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 358.0
MMS2_k127_707238_0 lysyl-tRNA aminoacylation K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 589.0
MMS2_k127_707238_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 398.0
MMS2_k127_707238_2 nucleoside metabolic process K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 301.0
MMS2_k127_707238_3 HIT domain K01518,K02503 - 3.6.1.17 0.000000000000000000000000000000000000000002447 160.0
MMS2_k127_707238_4 OsmC-like protein K07397 - - 0.000000000000000000000000000007627 123.0
MMS2_k127_707238_5 - - - - 0.000001265 51.0
MMS2_k127_71790_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 3.881e-240 746.0
MMS2_k127_71790_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 291.0
MMS2_k127_71790_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002349 272.0
MMS2_k127_71790_3 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000002322 213.0
MMS2_k127_71790_4 Domain of unknown function (DUF1940) - - - 0.000000000000000001005 89.0
MMS2_k127_724594_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 481.0
MMS2_k127_724594_1 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004452 274.0
MMS2_k127_724594_2 COG0668 Small-conductance mechanosensitive channel K16052 - - 0.000000000000000000000005365 114.0
MMS2_k127_724594_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000001045 68.0
MMS2_k127_749984_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 492.0
MMS2_k127_749984_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001535 263.0
MMS2_k127_749984_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000002524 199.0
MMS2_k127_749984_3 Protein of unknown function (DUF3198) - - - 0.0000000000002336 74.0
MMS2_k127_764546_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008489 409.0
MMS2_k127_764546_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000002441 167.0
MMS2_k127_803449_0 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 289.0
MMS2_k127_803449_1 membrane - - - 0.0000000000000000000000000000000000007217 149.0
MMS2_k127_833748_0 DALR anticodon binding domain K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 498.0
MMS2_k127_833748_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000009162 269.0
MMS2_k127_833748_2 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000001568 143.0
MMS2_k127_833748_3 ABC1 family - - - 0.00000000000000000000000006134 110.0
MMS2_k127_856730_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 5.562e-299 924.0
MMS2_k127_856730_1 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 400.0
MMS2_k127_856730_10 - - - - 0.00000000001565 73.0
MMS2_k127_856730_12 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000005305 53.0
MMS2_k127_856730_2 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000001091 254.0
MMS2_k127_856730_3 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000000008217 177.0
MMS2_k127_856730_4 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000006171 181.0
MMS2_k127_856730_5 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000003761 150.0
MMS2_k127_856730_6 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000005689 135.0
MMS2_k127_856730_7 Acetyltransferase (GNAT) family K06977 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - 0.0000000000000000000000000004537 115.0
MMS2_k127_856730_8 ester cyclase - - - 0.00000000000002083 78.0
MMS2_k127_856730_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000001339 83.0
MMS2_k127_874118_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 369.0
MMS2_k127_874118_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000001507 200.0
MMS2_k127_874118_2 snoRNA binding domain, fibrillarin K14564 - - 0.00000000000000000000000000000001591 137.0
MMS2_k127_874118_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000003724 111.0
MMS2_k127_875281_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 635.0
MMS2_k127_875281_1 Transcriptional regulator, TrmB - - - 0.000000000000000000000000000000000000000000000000000005375 191.0
MMS2_k127_875281_2 Uncharacterised protein family (UPF0147) K09721 - - 0.000000000000000000000000000000002061 132.0
MMS2_k127_875281_3 COG1522 Transcriptional regulators K03718 - - 0.000000000000000000000001375 106.0
MMS2_k127_875281_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000009672 64.0
MMS2_k127_880986_0 transferase activity, transferring acyl groups K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 595.0
MMS2_k127_880986_1 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 456.0
MMS2_k127_880986_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 310.0
MMS2_k127_880986_3 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004862 267.0
MMS2_k127_880986_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000002352 229.0
MMS2_k127_880986_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000002716 222.0
MMS2_k127_880986_6 2-phosphosulfolactate phosphatase activity K05979 - 3.1.3.71 0.0000000000000000000000000000000000000001785 158.0
MMS2_k127_880986_7 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000009212 156.0
MMS2_k127_880986_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000001012 79.0
MMS2_k127_880986_9 CAAX protease self-immunity - - - 0.00000005591 64.0
MMS2_k127_900385_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 3.915e-216 675.0
MMS2_k127_900385_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 599.0
MMS2_k127_900385_10 Major Facilitator Superfamily - - - 0.000000000000000000000007601 104.0
MMS2_k127_900385_11 4Fe-4S binding domain - - - 0.000000000000000000000589 96.0
MMS2_k127_900385_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 570.0
MMS2_k127_900385_3 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 409.0
MMS2_k127_900385_4 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 373.0
MMS2_k127_900385_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000001609 239.0
MMS2_k127_900385_6 PFAM Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000000000000000000000001352 219.0
MMS2_k127_900385_7 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000009265 163.0
MMS2_k127_900385_8 C2C2 Zinc finger K03057 - - 0.0000000000000000000000000000000000000000005151 158.0
MMS2_k127_900385_9 Uridine phosphorylase K00757 - 2.4.2.3 0.0000000000000000000000000000000008697 139.0
MMS2_k127_909508_0 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 314.0
MMS2_k127_909508_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000007096 262.0
MMS2_k127_909508_2 RNA cap guanine-N2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001118 216.0
MMS2_k127_909508_3 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner- Doudoroff pathway K18124 GO:0000166,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005534,GO:0005536,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019320,GO:0019388,GO:0019595,GO:0022607,GO:0030246,GO:0033498,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046430,GO:0047910,GO:0047936,GO:0048029,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051262,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.360 0.000000000000000000000000000003346 121.0
MMS2_k127_974740_0 PP-loop family - - - 0.000000000000000000000000000000000000000000000000000000000001535 213.0
MMS2_k127_974740_1 phosphatase activity K07025,K08723 - 3.1.3.5 0.000000000000000000000000000000000000000004051 163.0