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Overview

ID MAG02762
Name MMS2_bin.79
Sample SMP0065
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order Thermoplasmatales
Family Thermoplasmataceae
Genus UBA582
Species
Assembly information
Completeness (%) 77.33
Contamination (%) 0.1
GC content (%) 46.0
N50 (bp) 8,395
Genome size (bp) 1,296,683

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1279

Gene name Description KEGG GOs EC E-value Score Sequence
MMS2_k127_1020308_0 GNAT acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000008451 211.0
MMS2_k127_1020308_1 Chromate resistance - - - 0.0000000000000000000000000000000000000000000001319 172.0
MMS2_k127_1020308_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000157 135.0
MMS2_k127_1020308_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000006306 82.0
MMS2_k127_1020308_4 Putative antitoxin - - - 0.0000002703 55.0
MMS2_k127_1051715_0 KH domain K07041 - - 4.255e-318 983.0
MMS2_k127_1051715_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 459.0
MMS2_k127_1051715_2 1-deoxy-D-xylulose-5-phosphate synthase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 364.0
MMS2_k127_1051715_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001 240.0
MMS2_k127_1051715_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000007201 192.0
MMS2_k127_105449_0 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005322 289.0
MMS2_k127_105449_1 PFAM regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000001471 169.0
MMS2_k127_105449_2 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.0000000000000000000000000003396 117.0
MMS2_k127_1088953_0 Tricorn protease C1 domain K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 569.0
MMS2_k127_1088953_1 ATPases associated with a variety of cellular activities K00400,K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 391.0
MMS2_k127_1088953_2 - - - - 0.00000003467 60.0
MMS2_k127_1098801_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 307.0
MMS2_k127_1098801_1 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 287.0
MMS2_k127_1098801_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000002909 145.0
MMS2_k127_1098801_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000004367 144.0
MMS2_k127_1098801_4 - - - - 0.00000000000000001264 88.0
MMS2_k127_1098801_5 amine dehydrogenase activity - - - 0.0000000000439 75.0
MMS2_k127_1110552_0 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000222 219.0
MMS2_k127_1110552_1 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000001378 176.0
MMS2_k127_1110552_2 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.000000000000000000000000000007004 124.0
MMS2_k127_1110552_3 Sodium/hydrogen exchanger family - - - 0.000000000000004581 81.0
MMS2_k127_1125845_0 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner- Doudoroff pathway K18124 GO:0000166,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005534,GO:0005536,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019320,GO:0019388,GO:0019595,GO:0022607,GO:0030246,GO:0033498,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046430,GO:0047910,GO:0047936,GO:0048029,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051262,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.360 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 450.0
MMS2_k127_1125845_1 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 423.0
MMS2_k127_1125845_10 - - - - 0.0000000000000000000000000000000000004649 143.0
MMS2_k127_1125845_11 - - - - 0.0000000000000000000000000000009789 126.0
MMS2_k127_1125845_12 DNA polymerase - - - 0.0000000000000000000000000000469 124.0
MMS2_k127_1125845_13 - - - - 0.000000000000000000000004545 109.0
MMS2_k127_1125845_14 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0008864 51.0
MMS2_k127_1125845_2 TrkA-C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 413.0
MMS2_k127_1125845_3 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 353.0
MMS2_k127_1125845_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 347.0
MMS2_k127_1125845_5 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001314 275.0
MMS2_k127_1125845_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001997 276.0
MMS2_k127_1125845_7 RNA cap guanine-N2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001431 215.0
MMS2_k127_1125845_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000001455 204.0
MMS2_k127_1125845_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000002869 169.0
MMS2_k127_113069_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 375.0
MMS2_k127_113069_1 Dihydrodipicolinate synthetase family K11395 - 4.1.2.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001272 278.0
MMS2_k127_113069_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000008928 212.0
MMS2_k127_113069_3 Aldehyde dehydrogenase family K15038 - 1.2.1.76 0.0000000000000000000000000000000000000000001144 161.0
MMS2_k127_113069_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K03929 - - 0.00000000000000000001117 99.0
MMS2_k127_1156913_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 430.0
MMS2_k127_1156913_1 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000001125 268.0
MMS2_k127_1156913_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000002206 210.0
MMS2_k127_1156913_3 Ferric uptake regulator family K09825 - - 0.000000000000000000000000001017 117.0
MMS2_k127_1160992_0 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.0 1147.0
MMS2_k127_1160992_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006787 278.0
MMS2_k127_1160992_2 Putative esterase - - - 0.0000001772 54.0
MMS2_k127_1161429_0 HELICc2 K10844 - 3.6.4.12 2.728e-206 659.0
MMS2_k127_1161429_1 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 445.0
MMS2_k127_1161429_10 Putative tRNA binding domain K06878 - - 0.0000000000000000000000000000000001001 136.0
MMS2_k127_1161429_11 - - - - 0.000000000000000000000002737 105.0
MMS2_k127_1161429_12 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000004429 102.0
MMS2_k127_1161429_13 - - - - 0.0000000000126 67.0
MMS2_k127_1161429_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000007098 67.0
MMS2_k127_1161429_2 DNA-binding transcription factor activity K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006763 257.0
MMS2_k127_1161429_3 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000003342 229.0
MMS2_k127_1161429_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000003048 220.0
MMS2_k127_1161429_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000006422 186.0
MMS2_k127_1161429_6 - - - - 0.00000000000000000000000000000000000000000000000004248 187.0
MMS2_k127_1161429_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000002873 178.0
MMS2_k127_1161429_8 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000007701 154.0
MMS2_k127_1161429_9 - K07103 - - 0.0000000000000000000000000000000000002109 148.0
MMS2_k127_1193011_0 Domain of unknown function (DUF929) - - - 0.00000000000000000000000003768 118.0
MMS2_k127_1193011_1 V4R K07013 - - 0.000000000000000009807 91.0
MMS2_k127_1193011_2 Phosphoesterase family - - - 0.000001102 55.0
MMS2_k127_1205209_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000469 184.0
MMS2_k127_1205209_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000002656 179.0
MMS2_k127_1205209_2 Regulatory protein Crp K07730 - - 0.00000000000000000000000000000000000000000004227 169.0
MMS2_k127_1205209_3 - - - - 0.00000000001635 70.0
MMS2_k127_1238097_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005874 242.0
MMS2_k127_1238097_1 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000003906 209.0
MMS2_k127_1238097_2 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000008324 199.0
MMS2_k127_1238097_3 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000001102 202.0
MMS2_k127_1238097_4 aspartate carbamoyltransferase activity K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000008676 167.0
MMS2_k127_1238097_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000002477 82.0
MMS2_k127_1238097_6 Large family of predicted nucleotide-binding domains K07158 - - 0.00000000000003965 76.0
MMS2_k127_1238097_7 - - - - 0.0000000002074 66.0
MMS2_k127_1238097_8 - - - - 0.000000002117 64.0
MMS2_k127_1245124_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 421.0
MMS2_k127_1245124_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 314.0
MMS2_k127_1245124_2 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000005666 169.0
MMS2_k127_1245124_3 ABC-2 type transporter K01992 - - 0.000000000001792 70.0
MMS2_k127_127111_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 410.0
MMS2_k127_127111_1 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000002239 179.0
MMS2_k127_127111_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000000002116 93.0
MMS2_k127_127111_3 Protein of unknown function (DUF998) - - - 0.0000000000000000005937 94.0
MMS2_k127_1273147_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 566.0
MMS2_k127_1273147_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 527.0
MMS2_k127_1273147_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 363.0
MMS2_k127_1273147_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 329.0
MMS2_k127_1273147_4 Met-10+ like-protein K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000001057 245.0
MMS2_k127_1273147_5 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000000007378 178.0
MMS2_k127_1273147_6 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000001908 118.0
MMS2_k127_1273147_7 Glycosyl transferase family 21 K00786 - - 0.000000000000000000003398 97.0
MMS2_k127_1290600_0 Molybdopterin oxidoreductase Fe4S4 K00123 - 1.17.1.9 4.026e-259 816.0
MMS2_k127_1290600_1 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000365 273.0
MMS2_k127_1290600_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000001754 213.0
MMS2_k127_1290600_3 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000005403 117.0
MMS2_k127_1327906_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.862e-238 754.0
MMS2_k127_1327906_1 histidine ammonia-lyase activity K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 524.0
MMS2_k127_1327906_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
MMS2_k127_1327906_3 Electron transfer flavoprotein, beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 317.0
MMS2_k127_1327906_4 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004806 282.0
MMS2_k127_1327906_5 FAD dependent oxidoreductase K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000335 226.0
MMS2_k127_1327906_6 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S - - - 0.0000000000000000000000000000000000000000000006412 166.0
MMS2_k127_1327906_7 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.00000000000000000000000000000000000000000008943 167.0
MMS2_k127_1327906_8 Cupin domain - - - 0.00000005426 64.0
MMS2_k127_1327906_9 PFAM PilT protein domain protein - - - 0.0000003057 58.0
MMS2_k127_1333219_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846,K16850 - 4.2.1.7,4.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 569.0
MMS2_k127_1333219_1 Aldehyde dehydrogenase family K15038 - 1.2.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 387.0
MMS2_k127_1333219_2 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 362.0
MMS2_k127_1333219_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000005749 248.0
MMS2_k127_1333219_4 PFAM regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000001175 167.0
MMS2_k127_1333219_5 SAF K16845,K16849 - 4.2.1.7,4.4.1.24 0.000000000000000000000001322 105.0
MMS2_k127_1380733_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.0 1242.0
MMS2_k127_1380733_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 493.0
MMS2_k127_1380733_2 PRC-barrel domain - - - 0.0000000001053 66.0
MMS2_k127_1380733_3 ABC-2 family transporter protein K01992 - - 0.000007813 55.0
MMS2_k127_138267_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 520.0
MMS2_k127_138267_1 MmgE/PrpD family K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 467.0
MMS2_k127_138267_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 332.0
MMS2_k127_138267_3 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
MMS2_k127_138267_4 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000003034 199.0
MMS2_k127_138267_5 Alanine dehydrogenase/PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000003817 141.0
MMS2_k127_138267_6 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000005094 122.0
MMS2_k127_1390754_0 PFAM CBS domain K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 378.0
MMS2_k127_1390754_1 PFAM Rieske 2Fe-2S domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002964 227.0
MMS2_k127_1417709_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.637e-233 739.0
MMS2_k127_1417709_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.506e-227 715.0
MMS2_k127_1417709_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000001243 165.0
MMS2_k127_1417709_11 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000001451 148.0
MMS2_k127_1417709_12 carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000001362 82.0
MMS2_k127_1417709_13 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000001291 75.0
MMS2_k127_1417709_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000002877 61.0
MMS2_k127_1417709_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 536.0
MMS2_k127_1417709_3 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 357.0
MMS2_k127_1417709_4 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 316.0
MMS2_k127_1417709_5 structural constituent of ribosome K02877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 294.0
MMS2_k127_1417709_6 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000001281 239.0
MMS2_k127_1417709_7 PFAM metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000007947 234.0
MMS2_k127_1417709_8 methyltransferase - - - 0.000000000000000000000000000000000000000000000006742 182.0
MMS2_k127_1417709_9 - - - - 0.0000000000000000000000000000000000000000004056 167.0
MMS2_k127_1467819_0 DNA polymerase type-B family K02319 - 2.7.7.7 4.445e-309 964.0
MMS2_k127_1467819_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 354.0
MMS2_k127_1467819_10 - - - - 0.000000000000006211 79.0
MMS2_k127_1467819_11 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.000001366 59.0
MMS2_k127_1467819_12 transcriptional regulator - - - 0.0005136 48.0
MMS2_k127_1467819_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 346.0
MMS2_k127_1467819_3 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 343.0
MMS2_k127_1467819_4 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003758 274.0
MMS2_k127_1467819_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005822 262.0
MMS2_k127_1467819_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000006439 200.0
MMS2_k127_1467819_7 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000002676 191.0
MMS2_k127_1467819_8 - - - - 0.0000000000000000000001078 102.0
MMS2_k127_1467819_9 Putative modulator of DNA gyrase K03568 - - 0.000000000000000004563 88.0
MMS2_k127_1496628_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341,K22167 - 1.5.98.3,1.6.5.3 3.844e-212 676.0
MMS2_k127_1496628_1 Proton-conducting membrane transporter K00342,K22168 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 487.0
MMS2_k127_1496628_10 mttA/Hcf106 family K03116 - - 0.00000000000000000001928 94.0
MMS2_k127_1496628_11 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000004762 87.0
MMS2_k127_1496628_12 - - - - 0.0000000000002736 74.0
MMS2_k127_1496628_13 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.0000000000009377 68.0
MMS2_k127_1496628_2 Proton-conducting membrane transporter K00343,K22169 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 486.0
MMS2_k127_1496628_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 414.0
MMS2_k127_1496628_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 345.0
MMS2_k127_1496628_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 265.0
MMS2_k127_1496628_6 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000000000000000001165 213.0
MMS2_k127_1496628_7 - - - - 0.00000000000000000000000002258 110.0
MMS2_k127_1496628_8 Thermoplasma acidophilum protein TA0956 - - - 0.00000000000000000000000008358 110.0
MMS2_k127_1496628_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000003438 100.0
MMS2_k127_1508804_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000002271 248.0
MMS2_k127_1508804_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000008826 173.0
MMS2_k127_1508804_2 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000001247 117.0
MMS2_k127_1536917_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 1.061e-259 820.0
MMS2_k127_1536917_1 Catalyzes the transfer of the formyl group from N- formylglutamate to tetrahydrofolate (THF) to yield 5- formyltetrahydrofolate (5-CHO-THF) and glutamate (Glu). The triglutamate form of 5-CHO-THF (5-CHO-THF-Glu3) can also be used as substrate. It can also catalyzes the transfer of the formimino group from N-formiminoglutamate to tetrahydrofolate (THF) to yield 5-formiminotetrahydrofolate (5-NH CH-THF) and glutamate (Glu). It can replace YgfA to catalyzes the irreversible ATP-dependent transformation of 5-CHO-THF to form 5,10-methenyltetrahydrofolate (5,10-CH THF) K00603 - 2.1.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 397.0
MMS2_k127_1536917_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 381.0
MMS2_k127_1536917_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000002868 180.0
MMS2_k127_1536917_5 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000009282 154.0
MMS2_k127_1536917_6 Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000002881 124.0
MMS2_k127_1536917_7 Protein of unknown function (DUF1059) - - - 0.000000000000000008595 85.0
MMS2_k127_156474_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.686e-216 690.0
MMS2_k127_156474_1 C-terminal region of MMR_HSR1 domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 428.0
MMS2_k127_156474_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000000000000000000005851 159.0
MMS2_k127_156474_3 PFAM Mechanosensitive ion channel - - - 0.000000000000000000000000000000000001189 150.0
MMS2_k127_156474_4 Methyltransferase domain K02493 - 2.1.1.297 0.000000000000000000000000000000000003549 144.0
MMS2_k127_156474_5 Protein of unknown function (DUF3800) - - - 0.00000000000000003863 91.0
MMS2_k127_157325_0 Major Facilitator Superfamily - - - 3.355e-206 657.0
MMS2_k127_157325_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003491 264.0
MMS2_k127_157325_2 DNA methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000002707 241.0
MMS2_k127_157325_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000001281 218.0
MMS2_k127_157325_4 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000001896 184.0
MMS2_k127_157325_5 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000008501 131.0
MMS2_k127_157325_6 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000009357 86.0
MMS2_k127_1628203_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 297.0
MMS2_k127_1628203_1 phenylalanine-tRNA ligase activity K01890 - 6.1.1.20 0.0000000000000000000001102 102.0
MMS2_k127_1628203_2 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000724 81.0
MMS2_k127_1628203_3 Ribbon-helix-helix protein, copG family K07722 - - 0.000000000000003877 79.0
MMS2_k127_1628203_4 - - - - 0.00005332 54.0
MMS2_k127_1640576_0 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 396.0
MMS2_k127_1640576_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 316.0
MMS2_k127_1640576_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 308.0
MMS2_k127_1640576_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001417 276.0
MMS2_k127_1640576_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000004923 231.0
MMS2_k127_1640576_5 PFAM aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001971 237.0
MMS2_k127_1640576_6 PFAM Protein kinase domain - - - 0.00000000001162 75.0
MMS2_k127_1640576_7 Papain family cysteine protease - - - 0.0000002214 64.0
MMS2_k127_1661844_0 succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative mitochondrial subgroup K00239,K00244 - 1.3.5.1,1.3.5.4 4.594e-203 647.0
MMS2_k127_1661844_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 413.0
MMS2_k127_1661844_10 transcriptional - - - 0.00000000000000000000000000006093 123.0
MMS2_k127_1661844_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 388.0
MMS2_k127_1661844_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 309.0
MMS2_k127_1661844_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000301 236.0
MMS2_k127_1661844_5 pfkB family carbohydrate kinase K22026 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006213,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008617,GO:0008906,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009129,GO:0009130,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042278,GO:0042455,GO:0043167,GO:0043168,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046033,GO:0046035,GO:0046085,GO:0046087,GO:0046102,GO:0046128,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1905108 2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000001412 225.0
MMS2_k127_1661844_6 Molybdopterin oxidoreductase Fe4S4 K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000009023 195.0
MMS2_k127_1661844_7 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000000000000002383 191.0
MMS2_k127_1661844_8 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000000000000000000000000000000000002036 153.0
MMS2_k127_1661844_9 membrane - - - 0.0000000000000000000000000000000000001731 151.0
MMS2_k127_1700662_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 561.0
MMS2_k127_1700662_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 451.0
MMS2_k127_1700662_2 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 315.0
MMS2_k127_1700662_3 chorismate binding enzyme K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006837 278.0
MMS2_k127_1700662_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000002849 212.0
MMS2_k127_1700662_5 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000901 192.0
MMS2_k127_1700662_6 Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000003344 187.0
MMS2_k127_1700662_7 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000004737 175.0
MMS2_k127_1700662_8 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000002799 119.0
MMS2_k127_1700662_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000001917 56.0
MMS2_k127_171339_0 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000005506 236.0
MMS2_k127_171339_1 Cupin domain K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000001003 195.0
MMS2_k127_171339_2 carboxylic acid catabolic process K01736 - 4.2.3.5 0.00000000000000000000001202 102.0
MMS2_k127_171339_3 Transcriptional regulator K07979 - - 0.0000000000000007696 82.0
MMS2_k127_171339_4 ABC-2 family transporter protein K01992 - - 0.000004141 57.0
MMS2_k127_171339_5 - - - - 0.00002093 53.0
MMS2_k127_171339_6 SdpI/YhfL protein family - - - 0.000124 51.0
MMS2_k127_174489_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1135.0
MMS2_k127_174489_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 392.0
MMS2_k127_174489_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002636 243.0
MMS2_k127_174489_3 antibiotic catabolic process - - - 0.000000000000000000000000000000000000000000000000000000151 201.0
MMS2_k127_174489_4 antibiotic catabolic process - - - 0.00000000000000000000000004659 115.0
MMS2_k127_1754632_0 Glycoside hydrolase family 38 central region K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001751 305.0
MMS2_k127_1754632_1 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000002535 220.0
MMS2_k127_1754632_2 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000002363 199.0
MMS2_k127_1757732_0 TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 537.0
MMS2_k127_1757732_1 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 443.0
MMS2_k127_1757732_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000004314 128.0
MMS2_k127_1798280_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 529.0
MMS2_k127_1798280_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 428.0
MMS2_k127_1798280_2 MCM OB domain K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005996 263.0
MMS2_k127_1798280_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000007546 161.0
MMS2_k127_1798280_4 - - - - 0.00000000000000000000000000001539 126.0
MMS2_k127_1798280_5 glutamate synthase K00266,K20202 - 1.4.1.13,1.4.1.14,1.8.1.19 0.0000000000000004317 79.0
MMS2_k127_1874058_0 MMPL family K06994 - - 2.397e-206 679.0
MMS2_k127_1874058_1 COG1522 Transcriptional regulators K03718 - - 0.0000000000000000000004136 98.0
MMS2_k127_1874058_2 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000007711 79.0
MMS2_k127_1879684_0 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 428.0
MMS2_k127_1879684_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000002477 245.0
MMS2_k127_1879684_2 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000001667 213.0
MMS2_k127_1879684_3 Met-10+ like-protein K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000001398 215.0
MMS2_k127_1879684_4 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000000000003944 195.0
MMS2_k127_1879684_5 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000009131 119.0
MMS2_k127_1947773_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 449.0
MMS2_k127_1947773_1 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000008717 244.0
MMS2_k127_1947773_2 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000002482 175.0
MMS2_k127_1947773_3 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000001149 156.0
MMS2_k127_1947773_4 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.00000000000000000000000000000000000008982 152.0
MMS2_k127_1947773_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000001483 63.0
MMS2_k127_1949259_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1191.0
MMS2_k127_1949259_1 TopoisomeraseII K02470 - 5.99.1.3 3.045e-289 900.0
MMS2_k127_1949259_10 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 456.0
MMS2_k127_1949259_11 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 429.0
MMS2_k127_1949259_12 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 378.0
MMS2_k127_1949259_13 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 347.0
MMS2_k127_1949259_14 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 300.0
MMS2_k127_1949259_15 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000493 259.0
MMS2_k127_1949259_16 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000007899 192.0
MMS2_k127_1949259_17 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000006925 173.0
MMS2_k127_1949259_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000002273 151.0
MMS2_k127_1949259_19 - - - - 0.0000000000000000000000001696 107.0
MMS2_k127_1949259_2 DNA Topoisomerase IV K02469 - 5.99.1.3 1.861e-277 874.0
MMS2_k127_1949259_20 PRC-barrel domain protein - - - 0.0000000000000004892 80.0
MMS2_k127_1949259_21 - - - - 0.00000000000003556 76.0
MMS2_k127_1949259_22 small metal-binding protein - - - 0.00000000021 64.0
MMS2_k127_1949259_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.08e-262 826.0
MMS2_k127_1949259_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.795e-239 742.0
MMS2_k127_1949259_5 Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids K13722 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.102e-223 718.0
MMS2_k127_1949259_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.445e-204 649.0
MMS2_k127_1949259_7 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 575.0
MMS2_k127_1949259_8 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 545.0
MMS2_k127_1949259_9 alpha amylase, catalytic K01236 - 3.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 485.0
MMS2_k127_1995243_0 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 445.0
MMS2_k127_1995243_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 370.0
MMS2_k127_1995243_2 Acetamidase/Formamidase family K01426,K01455 - 3.5.1.4,3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 331.0
MMS2_k127_1995243_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 298.0
MMS2_k127_1995243_4 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004545 260.0
MMS2_k127_1995243_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000001183 238.0
MMS2_k127_1995243_6 Peptide-methionine (R)-S-oxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000008643 200.0
MMS2_k127_1995243_7 - - - - 0.000000000000000000000000000000000000000000000000002445 190.0
MMS2_k127_1995243_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0003059 46.0
MMS2_k127_2002512_0 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 484.0
MMS2_k127_2002512_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 276.0
MMS2_k127_2002512_2 Rieske-like [2Fe-2S] domain - - - 0.000000000000000000000000000007618 122.0
MMS2_k127_2041327_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 1.397e-205 651.0
MMS2_k127_2041327_1 PFAM Coenzyme A transferase K01026 - 2.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 536.0
MMS2_k127_2041327_2 2 iron, 2 sulfur cluster binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000001078 161.0
MMS2_k127_2041327_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000874 156.0
MMS2_k127_2041327_4 - - - - 0.000000000000001376 81.0
MMS2_k127_206753_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.111e-267 833.0
MMS2_k127_206753_1 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 424.0
MMS2_k127_206753_2 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000001129 203.0
MMS2_k127_206753_3 Queuosine biosynthesis protein K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000002452 183.0
MMS2_k127_206753_4 Pro-kumamolisin, activation domain - - - 0.000000000000000000000000000000000006321 158.0
MMS2_k127_206753_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000006634 124.0
MMS2_k127_206753_6 - K01385 - 3.4.23.42 0.0000000000000000007771 102.0
MMS2_k127_2071963_0 Peptidase family M13 K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 565.0
MMS2_k127_2071963_1 phosphoribosylformylglycinamidine cyclo-ligase activity K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 468.0
MMS2_k127_2071963_2 Uncharacterized protein family UPF0004 K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 445.0
MMS2_k127_2071963_3 Putative diphthamide synthesis protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 381.0
MMS2_k127_2071963_4 imidazolonepropionase activity K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 319.0
MMS2_k127_2071963_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000754 244.0
MMS2_k127_2071963_6 - - - - 0.000000000000000000000000000000000000009116 147.0
MMS2_k127_2071963_7 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000002158 142.0
MMS2_k127_2071963_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000004329 98.0
MMS2_k127_2071963_9 - K07991 - 3.4.23.52 0.00000000001206 74.0
MMS2_k127_2089402_0 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 595.0
MMS2_k127_2089402_1 Quinolinate phosphoribosyl transferase, C-terminal domain K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 444.0
MMS2_k127_2089402_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000001063 83.0
MMS2_k127_2089402_11 - - - - 0.00000000001827 72.0
MMS2_k127_2089402_2 cysteine-tRNA ligase activity K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 417.0
MMS2_k127_2089402_3 Zinc-binding dehydrogenase K15020 - 1.3.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 366.0
MMS2_k127_2089402_4 Citrate transporter K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 329.0
MMS2_k127_2089402_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000006771 176.0
MMS2_k127_2089402_6 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000001541 148.0
MMS2_k127_2089402_7 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000002257 141.0
MMS2_k127_2089402_8 - - - - 0.000000000000000001002 86.0
MMS2_k127_2089402_9 - - - - 0.0000000000000008044 78.0
MMS2_k127_2128725_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 453.0
MMS2_k127_2128725_1 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 403.0
MMS2_k127_2128725_2 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 356.0
MMS2_k127_2128725_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006178 280.0
MMS2_k127_2128725_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000005774 139.0
MMS2_k127_2134335_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 531.0
MMS2_k127_2134335_1 Peptidase family S49 K04773 - - 0.0000000000000000000000000002045 119.0
MMS2_k127_2134335_2 ATP-dependent DNA helicase activity K03657,K16898 - 3.6.4.12 0.0000000000000000000001528 106.0
MMS2_k127_2148200_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 454.0
MMS2_k127_2148200_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 413.0
MMS2_k127_2148200_10 - - - - 0.000001654 57.0
MMS2_k127_2148200_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006935 271.0
MMS2_k127_2148200_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003326 247.0
MMS2_k127_2148200_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000001905 246.0
MMS2_k127_2148200_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000003037 201.0
MMS2_k127_2148200_6 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000006863 191.0
MMS2_k127_2148200_7 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000001383 160.0
MMS2_k127_2148200_8 - - - - 0.00000000000000000000000000002247 127.0
MMS2_k127_2148200_9 PFAM type II secretion system protein E K07332 - - 0.000000000000000000008822 97.0
MMS2_k127_217777_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 420.0
MMS2_k127_217777_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000009223 169.0
MMS2_k127_217777_2 NurA - - - 0.0000000000000000000000000000000003655 141.0
MMS2_k127_2202253_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 593.0
MMS2_k127_2219711_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 390.0
MMS2_k127_2219711_1 Presenilin, signal peptide peptidase, family - - - 0.000000000000000000000000000000000000000000000000000000001359 212.0
MMS2_k127_2219711_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000005991 186.0
MMS2_k127_2221663_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 531.0
MMS2_k127_2221663_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 494.0
MMS2_k127_2221663_10 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002438 256.0
MMS2_k127_2221663_11 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000002181 219.0
MMS2_k127_2221663_12 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000562 212.0
MMS2_k127_2221663_13 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000007141 217.0
MMS2_k127_2221663_14 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000003002 156.0
MMS2_k127_2221663_15 dipeptide transport K02035 - - 0.000000000000000000000000000000000004544 156.0
MMS2_k127_2221663_16 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000004487 108.0
MMS2_k127_2221663_17 Binding-protein-dependent transport system inner membrane component K15552 - - 0.0000000000000000000003855 106.0
MMS2_k127_2221663_18 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000002347 100.0
MMS2_k127_2221663_19 Amidohydrolase K10220 - 4.2.1.83 0.000000000000162 75.0
MMS2_k127_2221663_2 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 390.0
MMS2_k127_2221663_20 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000006928 80.0
MMS2_k127_2221663_21 Domain in cystathionine beta-synthase and other proteins. - - - 0.0002483 50.0
MMS2_k127_2221663_3 Ethanolamine utilisation protein EutA K04019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 381.0
MMS2_k127_2221663_4 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 335.0
MMS2_k127_2221663_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 307.0
MMS2_k127_2221663_6 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 308.0
MMS2_k127_2221663_7 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 294.0
MMS2_k127_2221663_8 conserved protein, contains double-stranded beta-helix domain K00450,K06720 - 1.13.11.4,4.2.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000172 278.0
MMS2_k127_2221663_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001222 274.0
MMS2_k127_2260613_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 561.0
MMS2_k127_2260613_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001657 266.0
MMS2_k127_2260613_2 RNA-binding protein involved in rRNA processing K07569 - - 0.00000003725 57.0
MMS2_k127_2297668_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.0 1056.0
MMS2_k127_2297668_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K05308 GO:0003674,GO:0003824,GO:0008869,GO:0016829,GO:0016835,GO:0016836,GO:0047929 4.2.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 436.0
MMS2_k127_2297668_2 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 374.0
MMS2_k127_2297668_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000002721 229.0
MMS2_k127_233153_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 1.231e-249 782.0
MMS2_k127_233153_1 - - - - 0.0000000000000000000000000000000000000000000000000004198 187.0
MMS2_k127_233153_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000001796 104.0
MMS2_k127_2383168_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 345.0
MMS2_k127_2383168_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 301.0
MMS2_k127_2383168_2 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000000000000001641 157.0
MMS2_k127_2383168_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000003027 136.0
MMS2_k127_2383168_4 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000005879 94.0
MMS2_k127_2383168_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000008287 57.0
MMS2_k127_2386721_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 545.0
MMS2_k127_2386721_1 Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 306.0
MMS2_k127_2386721_2 Protein of unknown function (DUF981) K08980 - - 0.00000000000000000000000000000000000000000000000000000000000005551 219.0
MMS2_k127_2386721_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.00000000000000000000000000000000000000000000000002768 187.0
MMS2_k127_2386721_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000001083 134.0
MMS2_k127_2386721_5 hydrolase activity - - - 0.000000000000000000000000000005335 123.0
MMS2_k127_2386721_6 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000002448 122.0
MMS2_k127_2453643_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002666 244.0
MMS2_k127_2453643_1 PFAM cyclase family protein K07130 - 3.5.1.9 0.000000000000000000000000000000000000001143 154.0
MMS2_k127_2453643_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000006908 128.0
MMS2_k127_2453643_3 DNA-binding transcription factor activity K04096 - - 0.0000000000000000000000001587 108.0
MMS2_k127_2453643_4 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000008998 102.0
MMS2_k127_2453643_5 PIN domain of ribonuclease K07060 - - 0.0000001002 54.0
MMS2_k127_2453643_6 PFAM methyltransferase - - - 0.0000002546 62.0
MMS2_k127_2453643_7 - - - - 0.000001735 60.0
MMS2_k127_2460803_0 molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001223 249.0
MMS2_k127_2460803_1 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000001143 206.0
MMS2_k127_2496667_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively K04076 - 3.4.21.53 1.121e-296 921.0
MMS2_k127_2496667_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 7.687e-257 819.0
MMS2_k127_2496667_2 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 399.0
MMS2_k127_2496667_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 390.0
MMS2_k127_2496667_4 membrane-associated Zn-dependent proteases 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001181 287.0
MMS2_k127_2496667_5 ATP-NAD kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005129 250.0
MMS2_k127_2496667_6 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000009582 115.0
MMS2_k127_2531002_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000001964 132.0
MMS2_k127_2531002_1 membrane - - - 0.0000000000000000000000000000116 122.0
MMS2_k127_2531002_2 Transcriptional regulator - - - 0.000000000000001834 83.0
MMS2_k127_2531002_3 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.0000000000000556 80.0
MMS2_k127_2536469_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.639e-278 863.0
MMS2_k127_2536469_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 1.099e-253 793.0
MMS2_k127_2536469_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.821e-198 623.0
MMS2_k127_2536469_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 449.0
MMS2_k127_2536469_4 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 394.0
MMS2_k127_2536469_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000006325 190.0
MMS2_k127_2536469_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000001083 101.0
MMS2_k127_2536469_7 Aldehyde dehydrogenase family - - - 0.00000000000004876 84.0
MMS2_k127_2536469_8 Belongs to the ABC transporter superfamily K15583 - - 0.0000000000002428 81.0
MMS2_k127_2563689_0 Fumarase C C-terminus K01679 - 4.2.1.2 3.389e-202 640.0
MMS2_k127_2563689_1 Sugar (and other) transporter K08176,K08368,K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 536.0
MMS2_k127_2563689_10 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000009339 239.0
MMS2_k127_2563689_11 COG4608 ABC-type oligopeptide transport system, ATPase component K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000002811 228.0
MMS2_k127_2563689_12 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000008544 167.0
MMS2_k127_2563689_13 Binds to the 23S rRNA K02921 - - 0.00000000000000000000000000000000003053 135.0
MMS2_k127_2563689_14 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000003256 113.0
MMS2_k127_2563689_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000009274 96.0
MMS2_k127_2563689_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000004539 78.0
MMS2_k127_2563689_17 RNA polymerase K03051 - 2.7.7.6 0.00000001294 60.0
MMS2_k127_2563689_2 Cleaves H-Pro-AMC as well as a wide spectrum of amino acid substrates and several peptide substrates without a proline at the N-terminus K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 401.0
MMS2_k127_2563689_3 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 357.0
MMS2_k127_2563689_4 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 344.0
MMS2_k127_2563689_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 338.0
MMS2_k127_2563689_6 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 338.0
MMS2_k127_2563689_7 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 326.0
MMS2_k127_2563689_8 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 311.0
MMS2_k127_2563689_9 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002592 279.0
MMS2_k127_2592224_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001592 275.0
MMS2_k127_2592224_1 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.00000000000000000000000000000000000000000003058 171.0
MMS2_k127_2592224_2 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000001086 123.0
MMS2_k127_2592224_3 - - - - 0.0000000000000000000000006439 107.0
MMS2_k127_2592224_4 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000001067 103.0
MMS2_k127_2594489_0 PFAM Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 358.0
MMS2_k127_2594489_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004022 276.0
MMS2_k127_2594489_2 Amino acid kinase family K00928 - 2.7.2.4 0.0000000000000000000000004414 115.0
MMS2_k127_2594489_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000002149 66.0
MMS2_k127_261005_0 Glycosyl transferase family 21 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 346.0
MMS2_k127_261005_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 306.0
MMS2_k127_261005_2 amine dehydrogenase activity - - - 0.0000004791 62.0
MMS2_k127_2686386_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 512.0
MMS2_k127_2686386_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000001975 235.0
MMS2_k127_2686386_2 FAD binding domain - - - 0.00000000000000002345 85.0
MMS2_k127_2734703_0 membrane - - - 0.000000000000000000000000007163 117.0
MMS2_k127_2734703_1 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000000004276 110.0
MMS2_k127_2770876_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 468.0
MMS2_k127_2770876_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000007938 170.0
MMS2_k127_2798839_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 603.0
MMS2_k127_2798839_1 ERCC3/RAD25/XPB C-terminal helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 522.0
MMS2_k127_2798839_10 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K18816 - 2.3.1.82 0.00000001047 64.0
MMS2_k127_2798839_2 N-4 methylation of cytosine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 386.0
MMS2_k127_2798839_3 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 322.0
MMS2_k127_2798839_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001242 239.0
MMS2_k127_2798839_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000004964 192.0
MMS2_k127_2798839_6 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000001147 139.0
MMS2_k127_2798839_7 Protein of unknown function (DUF790) K09744 - - 0.000000000000000000000000000008137 134.0
MMS2_k127_2798839_8 Sugar (and other) transporter - - - 0.00000000000000002031 83.0
MMS2_k127_2798839_9 - - - - 0.00000000086 66.0
MMS2_k127_2844618_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.866e-200 633.0
MMS2_k127_2844618_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000008117 246.0
MMS2_k127_2844618_2 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000001611 219.0
MMS2_k127_2844618_3 - - - - 0.0000000000000000000000000000000000000000000000001839 183.0
MMS2_k127_2844618_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000002722 124.0
MMS2_k127_2844618_5 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000002205 121.0
MMS2_k127_2844618_6 nucleic acid-binding protein contains PIN domain - - - 0.0000000000000003793 83.0
MMS2_k127_2844618_7 - - - - 0.00001378 50.0
MMS2_k127_2854981_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 461.0
MMS2_k127_2854981_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 321.0
MMS2_k127_2854981_2 Catalyzes the phosphorylation of mevalonate (MVA) to yield mevalonate-3-phosphate. Functions in an alternative K18689 GO:0003674,GO:0003824,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576 2.7.1.185 0.000000000000000000000000000000000000000000000000000000000000000000002661 246.0
MMS2_k127_2854981_3 Domain of unknown function DUF302 - - - 0.00000000000000000000000008257 110.0
MMS2_k127_2854981_4 - - - - 0.0000000000000006538 91.0
MMS2_k127_2854981_5 but it may be involved in stabilization of the trimeric complex - - - 0.0000000000001022 73.0
MMS2_k127_2854981_6 Uncharacterized conserved protein (DUF2203) - - - 0.000001289 53.0
MMS2_k127_2856166_0 Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids K13722 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 531.0
MMS2_k127_2856166_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 437.0
MMS2_k127_2856166_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 353.0
MMS2_k127_2860811_0 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 290.0
MMS2_k127_2860811_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000003148 197.0
MMS2_k127_2860811_2 carboxylic acid catabolic process K01736 - 4.2.3.5 0.00000000000000000000000000000001258 133.0
MMS2_k127_2861475_0 NADP-dependent dehydrogenase of the nED (non- phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D- glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3- phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes K18128 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006081,GO:0006082,GO:0006090,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009255,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016620,GO:0016903,GO:0019637,GO:0019682,GO:0019752,GO:0022607,GO:0032787,GO:0042802,GO:0042803,GO:0043436,GO:0043796,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0061678,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901575 1.2.1.89 1.327e-211 667.0
MMS2_k127_2861475_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
MMS2_k127_2861475_2 - - - - 0.000000000000000000000000000000001268 143.0
MMS2_k127_2861475_3 - - - - 0.00000000000000000000000000000006333 134.0
MMS2_k127_2913261_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 366.0
MMS2_k127_2913261_1 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001541 261.0
MMS2_k127_2913261_2 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000002589 129.0
MMS2_k127_2913261_3 Ta0938 - - - 0.00000000000000000000000008409 112.0
MMS2_k127_2933851_0 Pfam:KH_3 K06865 - - 2.934e-237 747.0
MMS2_k127_2933851_1 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 329.0
MMS2_k127_2941418_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 457.0
MMS2_k127_2941418_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 332.0
MMS2_k127_2941418_10 TIGRFAM transposase, IS605 OrfB family K07496 - - 0.0006373 44.0
MMS2_k127_2941418_11 amine dehydrogenase activity - - - 0.0008576 48.0
MMS2_k127_2941418_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001534 261.0
MMS2_k127_2941418_3 ATPases associated with a variety of cellular activities K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000001013 231.0
MMS2_k127_2941418_4 COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000001718 215.0
MMS2_k127_2941418_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000003082 172.0
MMS2_k127_2941418_6 ATPase, AAA superfamily K06921 - - 0.000000002614 65.0
MMS2_k127_2941418_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000002832 63.0
MMS2_k127_2941418_8 Thermopsin K01385 - 3.4.23.42 0.00000002837 57.0
MMS2_k127_2941418_9 PFAM HEPN domain - - - 0.000004038 52.0
MMS2_k127_2960119_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2.462e-217 689.0
MMS2_k127_2960119_1 lyase activity K01714,K18127 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0008150,GO:0008152,GO:0008674,GO:0008675,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 4.1.2.51,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 332.0
MMS2_k127_2960119_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
MMS2_k127_2960119_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000001354 183.0
MMS2_k127_2960119_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000000001075 180.0
MMS2_k127_2960119_5 - - - - 0.00000000000000000000000000000000000000000000002326 177.0
MMS2_k127_2960119_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000000009527 121.0
MMS2_k127_2960119_7 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000009635 123.0
MMS2_k127_2960119_8 Binds to the 23S rRNA K02896 - - 0.0000000000000000002219 89.0
MMS2_k127_3012103_0 Bacterial extracellular solute-binding protein K17311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 426.0
MMS2_k127_3012103_1 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 411.0
MMS2_k127_3012103_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 353.0
MMS2_k127_3012103_3 ATPases associated with a variety of cellular activities K17314 - - 0.00000000000000000000000000000000000000000000000000000000000000009599 229.0
MMS2_k127_3012103_4 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000156 168.0
MMS2_k127_306353_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 591.0
MMS2_k127_306353_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 402.0
MMS2_k127_306353_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000489 192.0
MMS2_k127_306353_3 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000000004118 138.0
MMS2_k127_306353_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000004136 98.0
MMS2_k127_306353_5 Protein of unknown function (DUF3198) - - - 0.0000000000004377 74.0
MMS2_k127_3085660_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 4.737e-228 715.0
MMS2_k127_3085660_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 293.0
MMS2_k127_3085660_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000001835 189.0
MMS2_k127_3094328_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K03520 - 1.2.5.3 2.04e-196 633.0
MMS2_k127_3094328_1 ThiF family K21029,K22132 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000006404 242.0
MMS2_k127_3094328_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000005422 208.0
MMS2_k127_3094328_3 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000007202 186.0
MMS2_k127_31115_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 319.0
MMS2_k127_31115_1 phenylalanine-tRNA ligase activity K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 300.0
MMS2_k127_31115_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000005006 125.0
MMS2_k127_31115_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000131 54.0
MMS2_k127_318182_0 isoprenoid metabolic process K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 293.0
MMS2_k127_318182_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000002268 233.0
MMS2_k127_318182_2 AAA domain K18690 GO:0003674,GO:0003824,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576 2.7.1.186 0.000000000000000000000000000000000000000000000000000003441 196.0
MMS2_k127_318182_3 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000006924 195.0
MMS2_k127_318182_4 Transcriptional regulator - - - 0.00000000000000000000000000001066 122.0
MMS2_k127_318182_5 Glyoxalase-like domain - - - 0.000000000000000001257 90.0
MMS2_k127_318182_6 HNH endonuclease - - - 0.0000000262 63.0
MMS2_k127_3185807_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 566.0
MMS2_k127_3185807_1 Glucodextranase, domain N K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000007256 190.0
MMS2_k127_3185807_2 zinc-ribbon domain - - - 0.000000000000000004927 89.0
MMS2_k127_3199694_0 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 3.463e-317 991.0
MMS2_k127_3199694_1 Putative RNA methylase family UPF0020 K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000000000000000000000007729 239.0
MMS2_k127_3199694_2 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000003933 168.0
MMS2_k127_3199694_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000000000000000000000002187 139.0
MMS2_k127_3199694_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000001041 119.0
MMS2_k127_3199694_5 Winged helix DNA-binding domain - - - 0.000000000003411 72.0
MMS2_k127_3220042_0 pathogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 367.0
MMS2_k127_3220042_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003557 273.0
MMS2_k127_3220042_2 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000001739 136.0
MMS2_k127_3221871_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 587.0
MMS2_k127_3221871_1 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 291.0
MMS2_k127_3221871_2 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000009821 183.0
MMS2_k127_3221871_3 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000393 115.0
MMS2_k127_3314930_0 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004926 273.0
MMS2_k127_3314930_1 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000006464 223.0
MMS2_k127_3314930_2 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000001343 119.0
MMS2_k127_3314930_3 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000006111 75.0
MMS2_k127_3340943_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 441.0
MMS2_k127_3340943_1 This protein is involved in the repair of mismatches in DNA K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 341.0
MMS2_k127_3373491_0 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 333.0
MMS2_k127_3373491_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000006755 178.0
MMS2_k127_3373491_2 divalent heavy-metal cations transporter K07238 - - 0.000000000000000000000000000009436 128.0
MMS2_k127_3378921_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 1.848e-249 784.0
MMS2_k127_3378921_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 604.0
MMS2_k127_3378921_10 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000008157 132.0
MMS2_k127_3378921_11 Methyltransferase domain - - - 0.0000000000000000000000000001078 123.0
MMS2_k127_3378921_12 Ribosomal_L40e K02927 - - 0.0000000000000006218 78.0
MMS2_k127_3378921_13 Cytochrome C oxidase subunit II, periplasmic domain K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000021 76.0
MMS2_k127_3378921_14 - - - - 0.000000000068 68.0
MMS2_k127_3378921_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 419.0
MMS2_k127_3378921_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 356.0
MMS2_k127_3378921_4 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 347.0
MMS2_k127_3378921_5 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004671 294.0
MMS2_k127_3378921_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 253.0
MMS2_k127_3378921_7 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000003201 263.0
MMS2_k127_3378921_8 hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001058 246.0
MMS2_k127_3378921_9 adenyl ribonucleotide binding - - - 0.000000000000000000000000000000000000000000000000000000000000001757 223.0
MMS2_k127_3379947_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008469 283.0
MMS2_k127_3379947_1 GHMP kinases N terminal domain K00891 - 2.7.1.71 0.0000000000000000000000000001062 126.0
MMS2_k127_3379947_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000002085 69.0
MMS2_k127_3398361_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 342.0
MMS2_k127_3398361_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 326.0
MMS2_k127_3398361_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000976 256.0
MMS2_k127_3398361_3 Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001922 250.0
MMS2_k127_3398361_4 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000000005972 173.0
MMS2_k127_3441861_0 glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001261 287.0
MMS2_k127_3441861_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000003912 123.0
MMS2_k127_3447420_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 429.0
MMS2_k127_3447420_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000003496 227.0
MMS2_k127_3447420_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000007176 93.0
MMS2_k127_3447420_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000002437 67.0
MMS2_k127_3447420_4 Peptidase family S49 K04773 - - 0.0000005074 56.0
MMS2_k127_347201_1 - - - - 0.0000000000000000000000000000000000000000000000000005275 184.0
MMS2_k127_347201_2 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000008449 163.0
MMS2_k127_347201_3 PIN domain K07064 - - 0.0000000000000000000004188 102.0
MMS2_k127_347201_4 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.00000000000000002702 84.0
MMS2_k127_347201_5 acetyltransferase - - - 0.000000000003264 72.0
MMS2_k127_347201_6 - - - - 0.0000000002397 63.0
MMS2_k127_347201_7 - - - - 0.00000001245 58.0
MMS2_k127_35595_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 9.509e-242 769.0
MMS2_k127_35595_1 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 5.861e-234 739.0
MMS2_k127_35595_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000009419 204.0
MMS2_k127_35595_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000004375 196.0
MMS2_k127_35595_4 Protein similar to CwfJ C-terminus 1 K02503 - - 0.0000000000000000000000001057 111.0
MMS2_k127_35595_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000001731 109.0
MMS2_k127_35595_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000004294 66.0
MMS2_k127_35595_7 - - - - 0.00000008402 61.0
MMS2_k127_3561349_0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000007594 200.0
MMS2_k127_3561349_1 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000005577 196.0
MMS2_k127_3561349_2 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000001623 183.0
MMS2_k127_3576671_0 TCP-1/cpn60 chaperonin family K22447 - - 4.991e-257 801.0
MMS2_k127_3576671_1 Major Facilitator Superfamily - - - 1.702e-194 617.0
MMS2_k127_3576671_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 565.0
MMS2_k127_3576671_3 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 486.0
MMS2_k127_3576671_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 409.0
MMS2_k127_3576671_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 392.0
MMS2_k127_3576671_6 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 355.0
MMS2_k127_3576671_7 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000001371 211.0
MMS2_k127_3576671_8 Methyltransferase domain K07579 - - 0.000000000000000000000000000000000000000000000009528 178.0
MMS2_k127_3576671_9 - - - - 0.00000000000000000000000000001049 121.0
MMS2_k127_362311_0 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000783 264.0
MMS2_k127_362311_1 Related to alanyl-tRNA synthetase HxxxH domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 258.0
MMS2_k127_362311_2 Thermopsin K01385 - 3.4.23.42 0.000000000000000003549 99.0
MMS2_k127_362311_3 TIGRFAM methyltransferase FkbM family - - - 0.00000000000008201 81.0
MMS2_k127_362311_4 - - - - 0.00000000005066 74.0
MMS2_k127_362311_5 - - - - 0.0000002606 56.0
MMS2_k127_362311_6 Integrase core domain - - - 0.00003666 47.0
MMS2_k127_3625199_0 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 420.0
MMS2_k127_3625199_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000004461 263.0
MMS2_k127_3625199_2 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.00000000000000000000000001723 109.0
MMS2_k127_3706538_0 AAA-like domain K06915 - - 0.000000000000000000000000135 122.0
MMS2_k127_3706538_1 - - - - 0.00000000000000000163 88.0
MMS2_k127_3706538_2 - - - - 0.0000000000000002429 90.0
MMS2_k127_3706538_4 Thioesterase superfamily K01073 - 3.1.2.20 0.00000003031 56.0
MMS2_k127_3706538_5 - - - - 0.00000004816 58.0
MMS2_k127_3706538_6 PFAM ABC transporter related K15497 - 3.6.3.55 0.00006094 49.0
MMS2_k127_3735213_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 515.0
MMS2_k127_3735213_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 295.0
MMS2_k127_3735213_2 Steryl acetyl hydrolase K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002118 280.0
MMS2_k127_3735213_3 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004312 267.0
MMS2_k127_3735213_4 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000006861 219.0
MMS2_k127_3735213_6 Converts the D-glycero-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000007024 91.0
MMS2_k127_3735213_7 Phosphotransferase enzyme family K17910 - 2.7.1.190 0.00000000000001002 84.0
MMS2_k127_3735213_8 Amidohydrolase K03392 - 4.1.1.45 0.0000000002327 69.0
MMS2_k127_3736164_0 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 492.0
MMS2_k127_3736164_1 Radical SAM domain protein K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 468.0
MMS2_k127_3736164_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008721 271.0
MMS2_k127_3736164_3 Tricorn protease homolog K08676 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000007838 197.0
MMS2_k127_3739485_0 PFAM Aldehyde dehydrogenase K18978 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0008886,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 386.0
MMS2_k127_3739485_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000002327 76.0
MMS2_k127_3769710_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1424.0
MMS2_k127_3769710_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001629 250.0
MMS2_k127_3769710_2 - - - - 0.0000000000000000002001 89.0
MMS2_k127_3769710_3 Protein of unknown function (DUF1641) - - - 0.00000000000001044 81.0
MMS2_k127_3780598_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 404.0
MMS2_k127_3780598_1 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000176 267.0
MMS2_k127_3780598_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000009979 162.0
MMS2_k127_3780598_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000000002366 143.0
MMS2_k127_3780598_4 dTDP metabolic process K00943 - 2.7.4.9 0.00000000000000000000000000006093 123.0
MMS2_k127_3780598_5 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000008356 98.0
MMS2_k127_3780598_6 - - - - 0.000000003152 66.0
MMS2_k127_3821973_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 422.0
MMS2_k127_3821973_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003808 283.0
MMS2_k127_3821973_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000000000000004291 132.0
MMS2_k127_3821973_3 structural constituent of ribosome K02962 - - 0.00000000000003459 74.0
MMS2_k127_382896_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1160.0
MMS2_k127_382896_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 388.0
MMS2_k127_382896_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000001358 191.0
MMS2_k127_382896_3 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000001525 188.0
MMS2_k127_382896_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000003639 136.0
MMS2_k127_3839514_0 Amylo-alpha-1,6-glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 491.0
MMS2_k127_3839514_1 Binding-protein-dependent transport system inner membrane component K17312 - - 0.000000000000000000001979 99.0
MMS2_k127_3856476_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 433.0
MMS2_k127_3856476_1 Methyltransferase K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000213 237.0
MMS2_k127_3856476_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000001523 243.0
MMS2_k127_3856476_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000004323 215.0
MMS2_k127_3856476_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000001521 97.0
MMS2_k127_3856476_5 Cupin domain - - - 0.000000000000000001251 91.0
MMS2_k127_3856476_6 - - - - 0.000000000000009792 82.0
MMS2_k127_3860476_0 Glucodextranase, domain N K01178 - 3.2.1.3 8.639e-264 835.0
MMS2_k127_3860476_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 6.267e-208 651.0
MMS2_k127_3860476_10 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000003146 184.0
MMS2_k127_3860476_11 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000405 184.0
MMS2_k127_3860476_12 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000276 173.0
MMS2_k127_3860476_13 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000009911 160.0
MMS2_k127_3860476_14 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000002956 161.0
MMS2_k127_3860476_15 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000004663 144.0
MMS2_k127_3860476_16 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.0000000000000000000000000000000009817 132.0
MMS2_k127_3860476_17 - - - - 0.000000000000000000000000000000012 130.0
MMS2_k127_3860476_18 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000004743 102.0
MMS2_k127_3860476_19 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.0000000000000000001047 105.0
MMS2_k127_3860476_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.072e-194 617.0
MMS2_k127_3860476_20 4Fe-4S binding domain - - - 0.000000000000000000363 90.0
MMS2_k127_3860476_21 ABC transporter K01990 - - 0.000000000000003467 81.0
MMS2_k127_3860476_3 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 613.0
MMS2_k127_3860476_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 604.0
MMS2_k127_3860476_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 565.0
MMS2_k127_3860476_6 GDP-mannose 4,6 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 524.0
MMS2_k127_3860476_7 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 310.0
MMS2_k127_3860476_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000008514 251.0
MMS2_k127_3860476_9 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001212 222.0
MMS2_k127_38668_0 TCP-1/cpn60 chaperonin family K22447 - - 2.03e-253 791.0
MMS2_k127_38668_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.803e-208 668.0
MMS2_k127_38668_10 Periplasmic copper-binding protein (NosD) - - - 0.0000000000005573 82.0
MMS2_k127_38668_11 - K01385 - 3.4.23.42 0.000000005542 69.0
MMS2_k127_38668_2 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 377.0
MMS2_k127_38668_3 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 374.0
MMS2_k127_38668_4 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 322.0
MMS2_k127_38668_5 FAD linked K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000001213 219.0
MMS2_k127_38668_6 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00105,K00111 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 0.00000000000000000000000000000000000000000000000000000006095 213.0
MMS2_k127_38668_7 sterol carrier protein - - - 0.000000000000000000000000000000000000000000000001074 177.0
MMS2_k127_38668_8 Domain of unknown function (DUF1805) - - - 0.00000000000000000000008579 102.0
MMS2_k127_38668_9 Major Facilitator Superfamily - - - 0.0000000000000001864 82.0
MMS2_k127_3874812_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 583.0
MMS2_k127_3874812_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 590.0
MMS2_k127_3874812_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 377.0
MMS2_k127_3874812_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 376.0
MMS2_k127_3874812_4 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange (By similarity) K04484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005445 248.0
MMS2_k127_3874812_5 TIGRFAM indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000001283 145.0
MMS2_k127_3874812_6 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000003927 100.0
MMS2_k127_3874812_7 chromosome segregation and condensation protein ScpA K05896 - - 0.000003329 57.0
MMS2_k127_3886030_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002438 275.0
MMS2_k127_3886030_1 4Fe-4S dicluster domain - - - 0.0000000000001105 72.0
MMS2_k127_3886030_2 Enoyl-(Acyl carrier protein) reductase K16216 - 1.1.1.320 0.0003314 43.0
MMS2_k127_388848_0 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 332.0
MMS2_k127_388848_1 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000001437 181.0
MMS2_k127_388848_2 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000006027 183.0
MMS2_k127_388848_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000001124 119.0
MMS2_k127_3928480_0 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 434.0
MMS2_k127_3928480_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 296.0
MMS2_k127_3928480_2 ABC transporter, transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001102 287.0
MMS2_k127_3966526_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 537.0
MMS2_k127_3966526_1 COG3839 ABC-type sugar transport systems, ATPase components K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 376.0
MMS2_k127_3966526_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 368.0
MMS2_k127_3966526_3 PFAM extracellular solute-binding protein family 1 K15770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 369.0
MMS2_k127_3966526_4 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 349.0
MMS2_k127_3966526_5 COG1175 ABC-type sugar transport systems, permease components K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 329.0
MMS2_k127_3980995_0 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K01684,K05308,K14275 - 4.2.1.140,4.2.1.6,4.2.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 512.0
MMS2_k127_3980995_1 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 343.0
MMS2_k127_3980995_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003682 269.0
MMS2_k127_4009871_0 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 472.0
MMS2_k127_4009871_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009218 261.0
MMS2_k127_4009871_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
MMS2_k127_4009871_3 transcriptional - - - 0.0000001626 53.0
MMS2_k127_4021339_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 3.833e-225 708.0
MMS2_k127_4021339_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 465.0
MMS2_k127_4021339_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 310.0
MMS2_k127_4021339_3 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000001831 184.0
MMS2_k127_4021339_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000005379 113.0
MMS2_k127_4041588_0 Transposase K07484 - - 0.000000000000000000000000000002522 126.0
MMS2_k127_4041588_1 PFAM Transposase DDE domain - - - 0.000000000000000000000000512 110.0
MMS2_k127_4041588_2 Transposase (IS66 K07484 - - 0.00000000000000005085 85.0
MMS2_k127_4041588_3 TIGRFAM Small GTP-binding protein K06883 - - 0.0000000000005399 77.0
MMS2_k127_4066070_0 YHS domain K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 497.0
MMS2_k127_4066070_1 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 373.0
MMS2_k127_4066070_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 351.0
MMS2_k127_4066070_3 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 301.0
MMS2_k127_4066070_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 293.0
MMS2_k127_4066070_5 Chromate resistance - - - 0.00000000000000000000000000000000000000000000004446 174.0
MMS2_k127_4066070_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000001183 150.0
MMS2_k127_4066070_7 InterPro IPR014922 - - - 0.000000000000000000000000002366 114.0
MMS2_k127_4066070_8 Domain of unknown function (DUF427) - - - 0.0000000000000000005327 95.0
MMS2_k127_4071636_0 Peptidase family M20/M25/M40 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 414.0
MMS2_k127_4071636_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 395.0
MMS2_k127_4071636_2 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 369.0
MMS2_k127_4071636_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 343.0
MMS2_k127_4071636_4 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 310.0
MMS2_k127_4097776_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 612.0
MMS2_k127_4097776_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 595.0
MMS2_k127_4097776_10 Binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000005579 149.0
MMS2_k127_4097776_11 HTH DNA binding domain K06930 - - 0.0000000000000000000000000000000006448 138.0
MMS2_k127_4097776_12 snoRNA binding domain, fibrillarin K14564 - - 0.0000000000000000000000000000007599 128.0
MMS2_k127_4097776_13 prephenate dehydrogenase (NADP+) activity K00210 - 1.3.1.12 0.000000000000000000000000000002925 128.0
MMS2_k127_4097776_14 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile K04796 - - 0.000000000000000000000000236 107.0
MMS2_k127_4097776_15 structural constituent of ribosome K02978 - - 0.00000000000000005034 84.0
MMS2_k127_4097776_16 Chorismate mutase type II - - - 0.00000000000552 74.0
MMS2_k127_4097776_17 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000001345 66.0
MMS2_k127_4097776_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 509.0
MMS2_k127_4097776_3 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 505.0
MMS2_k127_4097776_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 494.0
MMS2_k127_4097776_5 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 334.0
MMS2_k127_4097776_6 translation initiation factor 2 subunit alpha K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001573 284.0
MMS2_k127_4097776_7 PFAM Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000007947 234.0
MMS2_k127_4097776_8 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000000000000000004204 213.0
MMS2_k127_4097776_9 Removes the phosphate from trehalose 6-phosphate K01087 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.12 0.00000000000000000000000000000000000000000000000003757 187.0
MMS2_k127_4108385_0 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 355.0
MMS2_k127_4108385_1 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001507 254.0
MMS2_k127_4108385_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000000000000468 197.0
MMS2_k127_4114878_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 6.802e-212 664.0
MMS2_k127_4114878_1 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 610.0
MMS2_k127_4114878_10 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000002412 151.0
MMS2_k127_4114878_11 segregation and condensation protein B K06024 - - 0.0000000000002498 76.0
MMS2_k127_4114878_12 Protein of unknown function (DUF1641) - - - 0.0000000006438 64.0
MMS2_k127_4114878_13 Succinyl-CoA ligase like flavodoxin domain - - - 0.0002579 52.0
MMS2_k127_4114878_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 460.0
MMS2_k127_4114878_3 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 353.0
MMS2_k127_4114878_4 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 344.0
MMS2_k127_4114878_5 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 321.0
MMS2_k127_4114878_6 PFAM elongation factor Tu, domain 2 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005123 277.0
MMS2_k127_4114878_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000006295 269.0
MMS2_k127_4114878_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000006476 192.0
MMS2_k127_4114878_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000007349 160.0
MMS2_k127_4142058_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 289.0
MMS2_k127_4142058_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008259 254.0
MMS2_k127_4142058_2 Belongs to the UPF0255 family - - - 0.0000000000000000000000000000000000000000000000000000002303 206.0
MMS2_k127_4142058_3 L-lysine catabolic process to acetate K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000001532 186.0
MMS2_k127_4142058_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000001743 188.0
MMS2_k127_4142058_5 Fumarylacetoacetate hydrolase domain-containing protein - - - 0.00000000000000000000000000000000000001247 156.0
MMS2_k127_4142058_6 Isochorismatase family - - - 0.00000000000000000003745 98.0
MMS2_k127_4150852_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 8.443e-228 727.0
MMS2_k127_4150852_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 487.0
MMS2_k127_4150852_2 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 356.0
MMS2_k127_4150852_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 297.0
MMS2_k127_4150852_4 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000000000000004591 194.0
MMS2_k127_4152821_0 Glycosyl transferases group 1 - - - 0.000000000000000001117 96.0
MMS2_k127_4152821_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000004402 78.0
MMS2_k127_4196793_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 377.0
MMS2_k127_4196793_1 Peptide methionine sulfoxide reductase K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000003955 208.0
MMS2_k127_4196793_2 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000001967 147.0
MMS2_k127_4196793_3 Iron dependent repressor, metal binding and dimerisation domain - - - 0.000000000000000000000000000000000002691 141.0
MMS2_k127_4196793_4 - - - - 0.00000000000000000004561 100.0
MMS2_k127_4197751_0 MOFRL family K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 311.0
MMS2_k127_4197751_1 Sulfurtransferase - - - 0.000000000000000001698 89.0
MMS2_k127_4197751_2 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000001069 53.0
MMS2_k127_4198396_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 497.0
MMS2_k127_4198396_1 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 413.0
MMS2_k127_4198396_2 Belongs to the peptidase M24B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 403.0
MMS2_k127_4198396_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 387.0
MMS2_k127_4198396_4 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 377.0
MMS2_k127_4198396_5 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 299.0
MMS2_k127_4198396_6 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005848 274.0
MMS2_k127_4198396_7 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000005927 168.0
MMS2_k127_4198396_8 Biotin-lipoyl like K00627 - 2.3.1.12 0.0000000000000000000000000000000000001044 148.0
MMS2_k127_4198396_9 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000001226 64.0
MMS2_k127_4206968_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1279.0
MMS2_k127_4206968_1 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 299.0
MMS2_k127_4206968_2 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005259 281.0
MMS2_k127_4206968_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000006643 243.0
MMS2_k127_4206968_4 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.000000000000000000000000000000000000000000000000000009178 194.0
MMS2_k127_4206968_5 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000000000000000001168 188.0
MMS2_k127_4206968_6 - - - - 0.0000000000001128 73.0
MMS2_k127_4206968_7 SCP-2 sterol transfer family - - - 0.00000006579 54.0
MMS2_k127_4206968_8 peptidase - - - 0.00000374 53.0
MMS2_k127_4252855_0 Radical SAM superfamily - - - 9.532e-265 825.0
MMS2_k127_4252855_1 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 519.0
MMS2_k127_4252855_3 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000811 114.0
MMS2_k127_4252855_4 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000665 106.0
MMS2_k127_4252855_5 Protein of unknown function, DUF393 - - - 0.000000000001337 74.0
MMS2_k127_4252855_8 - - - - 0.000000001887 62.0
MMS2_k127_4256165_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 486.0
MMS2_k127_4256165_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 317.0
MMS2_k127_4256165_2 Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like) K00171 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 299.0
MMS2_k127_4263312_0 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009836 269.0
MMS2_k127_4263312_1 COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519,K11178 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
MMS2_k127_4263312_2 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000004785 150.0
MMS2_k127_4263312_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000002242 110.0
MMS2_k127_4277622_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 2.934e-210 670.0
MMS2_k127_4277622_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000003648 182.0
MMS2_k127_4277622_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000000000000000000000207 164.0
MMS2_k127_4277622_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000009404 164.0
MMS2_k127_4277622_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000001116 152.0
MMS2_k127_4277622_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000006507 141.0
MMS2_k127_4277622_6 Probable molybdopterin binding domain K03638 - 2.7.7.75 0.0000000000000000000000000000000004921 136.0
MMS2_k127_4277622_7 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000002475 121.0
MMS2_k127_4306266_0 COG1290 Cytochrome b subunit of the bc complex K15879 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 505.0
MMS2_k127_4306266_1 PFAM Rieske 2Fe-2S domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009262 278.0
MMS2_k127_4306266_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000002841 219.0
MMS2_k127_4306266_3 - - - - 0.00000000000000000000000000000000000000000006154 178.0
MMS2_k127_4314898_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 9.319e-253 791.0
MMS2_k127_4314898_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 5.815e-211 663.0
MMS2_k127_4314898_10 Thermopsin K01385 - 3.4.23.42 0.00000000000000000000000000000000000000000000000000000000000000000000000005584 278.0
MMS2_k127_4314898_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000004923 231.0
MMS2_k127_4314898_12 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000003974 180.0
MMS2_k127_4314898_13 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000002645 155.0
MMS2_k127_4314898_14 - - - - 0.00000000000000000000000000000000006213 141.0
MMS2_k127_4314898_15 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000008609 138.0
MMS2_k127_4314898_16 ATP synthase subunit C K02124 - - 0.00000000000000000000000002258 110.0
MMS2_k127_4314898_17 Oxidoreductase family, C-terminal alpha beta domain K00118,K13020 - 1.1.1.335,1.1.99.28 0.0000000000000000000000004934 117.0
MMS2_k127_4314898_18 PFAM Isochorismatase - - - 0.00000000000000000000005725 105.0
MMS2_k127_4314898_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000008859 99.0
MMS2_k127_4314898_2 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 576.0
MMS2_k127_4314898_20 acylphosphatase activity K01512 - 3.6.1.7 0.0000000000000002486 81.0
MMS2_k127_4314898_21 - - - - 0.00000002261 63.0
MMS2_k127_4314898_22 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000002723 62.0
MMS2_k127_4314898_23 Membrane protein implicated in regulation of membrane protease activity - - - 0.0001872 48.0
MMS2_k127_4314898_3 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 552.0
MMS2_k127_4314898_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 459.0
MMS2_k127_4314898_5 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 454.0
MMS2_k127_4314898_6 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 349.0
MMS2_k127_4314898_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 301.0
MMS2_k127_4314898_8 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 300.0
MMS2_k127_4314898_9 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000049 267.0
MMS2_k127_4342352_0 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000242 82.0
MMS2_k127_4342352_1 Tetratricopeptide repeat - - - 0.0000000008476 68.0
MMS2_k127_4342352_2 - K01647 - 2.3.3.1 0.000000496 55.0
MMS2_k127_4342352_3 - K07171 - - 0.00000126 54.0
MMS2_k127_4347177_0 amidohydrolase K21613 - - 0.0000000000000000000000002091 109.0
MMS2_k127_4363344_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
MMS2_k127_4363344_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000431 259.0
MMS2_k127_4363344_2 Ornithine cyclodeaminase/mu-crystallin family K19244 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008218 261.0
MMS2_k127_4363344_3 Glycosyl transferase 4-like domain K19002 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 0.000000000000000000000000000000000000009922 159.0
MMS2_k127_4363344_4 protein, homolog of Cu resistance protein CopC - - - 0.000000000000000000000000000000000000132 148.0
MMS2_k127_4363344_5 - - - - 0.0000000000000000000000004908 107.0
MMS2_k127_4363344_6 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000003772 68.0
MMS2_k127_4380680_0 Enoyl-CoA hydratase/isomerase K15016 - 1.1.1.35,4.2.1.17 7.987e-253 796.0
MMS2_k127_4380680_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K00156 - 1.2.5.1 8.541e-214 677.0
MMS2_k127_4380680_10 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001729 244.0
MMS2_k127_4380680_11 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000006575 203.0
MMS2_k127_4380680_12 Cobalamin adenosyltransferase - - - 0.0000000000000000000000000000000000000000000001018 174.0
MMS2_k127_4380680_13 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000001412 80.0
MMS2_k127_4380680_14 sterol carrier protein - - - 0.0000001509 57.0
MMS2_k127_4380680_15 AsnC family - - - 0.00001378 50.0
MMS2_k127_4380680_2 Pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 600.0
MMS2_k127_4380680_3 of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 550.0
MMS2_k127_4380680_4 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 456.0
MMS2_k127_4380680_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 423.0
MMS2_k127_4380680_6 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 337.0
MMS2_k127_4380680_7 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 284.0
MMS2_k127_4380680_8 Threonyl and Alanyl tRNA synthetase second additional domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004862 250.0
MMS2_k127_4380680_9 Biotin-lipoyl like K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000004394 247.0
MMS2_k127_4394856_0 helicase superfamily c-terminal domain K03724 - - 0.0 1062.0
MMS2_k127_4394856_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.68e-259 818.0
MMS2_k127_4394856_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000002131 61.0
MMS2_k127_4394856_2 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 307.0
MMS2_k127_4394856_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000744 286.0
MMS2_k127_4394856_4 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 257.0
MMS2_k127_4394856_5 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000002658 235.0
MMS2_k127_4394856_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000496 217.0
MMS2_k127_4394856_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000006869 191.0
MMS2_k127_4394856_8 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000000000000000000001524 176.0
MMS2_k127_4394856_9 Located on the platform of the 30S subunit K02948 - - 0.000000000000000000000000002673 113.0
MMS2_k127_442271_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.937e-277 862.0
MMS2_k127_442271_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 452.0
MMS2_k127_442271_10 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000002343 230.0
MMS2_k127_442271_11 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000000006586 222.0
MMS2_k127_442271_12 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000564 240.0
MMS2_k127_442271_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000001662 207.0
MMS2_k127_442271_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000001768 196.0
MMS2_k127_442271_15 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000995 194.0
MMS2_k127_442271_16 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000000000000000000000002236 193.0
MMS2_k127_442271_17 This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02890 - - 0.000000000000000000000000000000000000000000000000002546 187.0
MMS2_k127_442271_18 structural constituent of ribosome K02912 - - 0.0000000000000000000000000000000000000000000000001475 179.0
MMS2_k127_442271_19 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000000000000000002646 180.0
MMS2_k127_442271_2 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 364.0
MMS2_k127_442271_20 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000002021 167.0
MMS2_k127_442271_21 posttranscriptional regulation of gene expression K03113 - - 0.0000000000000000000000000000000000000000001143 160.0
MMS2_k127_442271_22 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000002158 159.0
MMS2_k127_442271_23 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000007544 139.0
MMS2_k127_442271_24 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.00000000000000000000000000000009755 132.0
MMS2_k127_442271_25 ribosomal protein S14 K02954 - - 0.000000000000000000003015 93.0
MMS2_k127_442271_26 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000267 77.0
MMS2_k127_442271_27 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000001209 74.0
MMS2_k127_442271_28 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001069 72.0
MMS2_k127_442271_29 ribonuclease P RNA binding K03538 GO:0000172,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005655,GO:0005730,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019843,GO:0022613,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042134,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0003245 49.0
MMS2_k127_442271_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 342.0
MMS2_k127_442271_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 323.0
MMS2_k127_442271_5 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 295.0
MMS2_k127_442271_6 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 291.0
MMS2_k127_442271_7 rRNA binding K02987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008954 244.0
MMS2_k127_442271_8 adenylate kinase activity K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000007796 237.0
MMS2_k127_442271_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000004257 229.0
MMS2_k127_4423969_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 359.0
MMS2_k127_4423969_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000007271 156.0
MMS2_k127_4423969_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000000000000005532 125.0
MMS2_k127_4423969_3 ThiS family - - - 0.0000001111 55.0
MMS2_k127_4423969_4 HAD-hyrolase-like K07025 - - 0.0003683 45.0
MMS2_k127_4444626_0 Glycosyl transferase family 21 K00786 - - 0.000000000000000000000000000000000000000000000000000000008236 205.0
MMS2_k127_4444626_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000001176 175.0
MMS2_k127_4444626_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000007657 118.0
MMS2_k127_4444626_3 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000000000004591 89.0
MMS2_k127_4444626_4 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000001396 85.0
MMS2_k127_4444626_5 PFAM TPR repeat-containing protein - - - 0.00002874 58.0
MMS2_k127_4480488_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 450.0
MMS2_k127_4480488_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 443.0
MMS2_k127_4480488_2 HTH domain - - - 0.000000000000000000000000000000000000000000000000636 182.0
MMS2_k127_4506904_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 518.0
MMS2_k127_4506904_1 4-hydroxy-tetrahydrodipicolinate reductase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 425.0
MMS2_k127_4506904_2 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000003435 163.0
MMS2_k127_4506904_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000009087 158.0
MMS2_k127_4506904_4 PFAM NAD-dependent epimerase dehydratase K01784,K08678 - 4.1.1.35,5.1.3.2 0.0000000000000000000000000001045 128.0
MMS2_k127_4506904_5 protease with the C-terminal PDZ domain - - - 0.0006363 46.0
MMS2_k127_4512574_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 3.834e-223 703.0
MMS2_k127_4512574_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 302.0
MMS2_k127_4512574_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000004483 249.0
MMS2_k127_4512574_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004882 254.0
MMS2_k127_4512574_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000005829 231.0
MMS2_k127_4512574_5 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000001083 211.0
MMS2_k127_4512574_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000002816 157.0
MMS2_k127_4512574_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000108 71.0
MMS2_k127_4512574_8 phosphatidylinositol metabolic process - - - 0.0001824 54.0
MMS2_k127_4521533_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 518.0
MMS2_k127_4521533_1 Transposase K07484 - - 0.0005298 45.0
MMS2_k127_4539760_0 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000007233 96.0
MMS2_k127_4539760_1 Glycosyl transferase family 2 - - - 0.000000284 61.0
MMS2_k127_4539760_2 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000003775 54.0
MMS2_k127_4543714_0 tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 433.0
MMS2_k127_4543714_1 CARDB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 404.0
MMS2_k127_4543714_2 DALR anticodon binding domain K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 300.0
MMS2_k127_4543714_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000695 218.0
MMS2_k127_4543714_4 - - - - 0.0001259 47.0
MMS2_k127_4570025_0 Hydroxymethylglutaryl-coenzyme A reductase K00021,K00054 - 1.1.1.34,1.1.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 463.0
MMS2_k127_4570025_1 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.0000000000000000000000000000003465 127.0
MMS2_k127_4570025_2 tetratricopeptide - - - 0.0000000000000000000000000004166 124.0
MMS2_k127_4570025_3 AhpC/TSA family K03564 - 1.11.1.15 0.000000000001227 68.0
MMS2_k127_4572363_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1922.0
MMS2_k127_4572363_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1407.0
MMS2_k127_4572363_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 508.0
MMS2_k127_4572363_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 456.0
MMS2_k127_4572363_4 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000000005455 182.0
MMS2_k127_4572363_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000000000001056 109.0
MMS2_k127_4572363_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000005934 85.0
MMS2_k127_4574289_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.85e-271 844.0
MMS2_k127_4574289_1 lysyl-tRNA aminoacylation K04566 - 6.1.1.6 1.078e-194 618.0
MMS2_k127_4574289_10 protein conserved in archaea K09723 - - 0.00000000000000000003992 98.0
MMS2_k127_4574289_11 - - - - 0.0000000000000009667 78.0
MMS2_k127_4574289_12 HIT domain K01518,K02503 - 3.6.1.17 0.0000000000003817 71.0
MMS2_k127_4574289_2 nucleoside metabolic process K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 301.0
MMS2_k127_4574289_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 304.0
MMS2_k127_4574289_4 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 302.0
MMS2_k127_4574289_5 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000001428 234.0
MMS2_k127_4574289_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000006953 190.0
MMS2_k127_4574289_7 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000001014 169.0
MMS2_k127_4574289_8 OsmC-like protein K07397 - - 0.000000000000000000000000000000000009421 141.0
MMS2_k127_4574289_9 acetyltransferase - - - 0.00000000000000000000000000000003431 133.0
MMS2_k127_4575651_0 helicase superfamily c-terminal domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 456.0
MMS2_k127_4575651_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 383.0
MMS2_k127_4575651_2 helicase superfamily c-terminal domain K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 355.0
MMS2_k127_4575651_3 COG1995 Pyridoxal phosphate biosynthesis protein K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 328.0
MMS2_k127_4575651_4 SMART Metal-dependent phosphohydrolase, HD region K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001505 267.0
MMS2_k127_4575651_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000003729 224.0
MMS2_k127_4575651_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000008375 83.0
MMS2_k127_4633858_0 4Fe-4S single cluster domain K06937 - - 0.0 1055.0
MMS2_k127_4633858_1 leucyl-tRNA aminoacylation K01869 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 357.0
MMS2_k127_4633858_2 arginine decarboxylase activity K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 281.0
MMS2_k127_4633858_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00003229 52.0
MMS2_k127_4763997_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 396.0
MMS2_k127_4763997_1 - - - - 0.000000000000000000000000001509 115.0
MMS2_k127_4763997_2 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000008089 104.0
MMS2_k127_4763997_3 Belongs to the UPF0292 family - - - 0.0000000000000000000107 97.0
MMS2_k127_4763997_4 Oxidoreductase FAD-binding domain K00523,K14581,K16246,K18225 - 1.17.1.1,1.18.1.7 0.000000000005332 73.0
MMS2_k127_4774909_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 596.0
MMS2_k127_4774909_1 - - - - 0.000000000000000000000000000000000000000000008542 168.0
MMS2_k127_4774909_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000001318 72.0
MMS2_k127_4779290_0 Type IV secretory system Conjugative DNA transfer K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 552.0
MMS2_k127_4779290_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 303.0
MMS2_k127_4779290_2 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.0000000000000000000000000000000000000001774 171.0
MMS2_k127_4784696_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 442.0
MMS2_k127_4784696_1 4Fe-4S single cluster domain K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 368.0
MMS2_k127_4784696_2 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000007492 207.0
MMS2_k127_4784696_3 - - - - 0.00000000000000000000000000000000001005 143.0
MMS2_k127_4824070_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 445.0
MMS2_k127_4824070_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 401.0
MMS2_k127_4824070_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002546 276.0
MMS2_k127_4824070_3 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000001781 168.0
MMS2_k127_4996400_0 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000003442 151.0
MMS2_k127_4996400_1 PFAM peptidase M13 K01415 - 3.4.24.71 0.0000000000000000000000000000000555 132.0
MMS2_k127_4996400_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000006486 70.0
MMS2_k127_4998920_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000005375 235.0
MMS2_k127_4998920_1 Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000954 191.0
MMS2_k127_559698_0 Anticodon binding domain K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 486.0
MMS2_k127_559698_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 312.0
MMS2_k127_559698_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002641 271.0
MMS2_k127_559698_3 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000008316 128.0
MMS2_k127_559698_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000456 93.0
MMS2_k127_559698_5 transcriptional regulators - - - 0.000000000654 62.0
MMS2_k127_561905_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 343.0
MMS2_k127_561905_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 318.0
MMS2_k127_561905_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 317.0
MMS2_k127_561905_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 293.0
MMS2_k127_561905_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005002 281.0
MMS2_k127_561905_5 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002404 281.0
MMS2_k127_561905_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001733 271.0
MMS2_k127_561905_7 amidohydrolase K21613 - - 0.000000000000000000000000000002337 130.0
MMS2_k127_561905_8 K homology RNA-binding domain K06865 - - 0.00001035 48.0
MMS2_k127_589875_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 460.0
MMS2_k127_589875_1 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 417.0
MMS2_k127_589875_10 - - - - 0.00000000008325 73.0
MMS2_k127_589875_11 amine dehydrogenase activity - - - 0.0000001949 64.0
MMS2_k127_589875_2 PUA domain K07557 - 2.6.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 409.0
MMS2_k127_589875_3 Arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 364.0
MMS2_k127_589875_4 structural constituent of ribosome K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001008 278.0
MMS2_k127_589875_5 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004139 277.0
MMS2_k127_589875_6 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000006999 191.0
MMS2_k127_589875_7 - - - - 0.000000000000000000000000001134 119.0
MMS2_k127_589875_8 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold K03263 - - 0.00000000001238 70.0
MMS2_k127_589875_9 - - - - 0.00000000001943 71.0
MMS2_k127_596155_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 5.291e-294 914.0
MMS2_k127_596155_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004436 264.0
MMS2_k127_596155_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000395 161.0
MMS2_k127_596155_3 PIN domain - - - 0.00000000000000000003194 96.0
MMS2_k127_596155_4 - - - - 0.00000000004012 66.0
MMS2_k127_59772_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 338.0
MMS2_k127_59772_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000005305 143.0
MMS2_k127_59772_2 Winged helix DNA-binding domain - - - 0.0001854 53.0
MMS2_k127_612950_0 Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000001131 198.0
MMS2_k127_612950_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000001239 117.0
MMS2_k127_612950_2 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity) K01170 - 4.6.1.16 0.000000000000000000000000001016 123.0
MMS2_k127_612950_3 GTP-binding protein K06883 - - 0.0000000000000000000000009021 110.0
MMS2_k127_665033_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 7.419e-298 976.0
MMS2_k127_665033_1 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 477.0
MMS2_k127_665033_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 - 2.1.1.260 0.0000000000000000000000000000000000000000000000000000000000000000006103 235.0
MMS2_k127_665033_3 - - - - 0.0000000000000000000000000000000000000000000000000003238 191.0
MMS2_k127_665033_4 structural constituent of ribosome K02956 - - 0.0000000000000000000000000000000000000000002507 163.0
MMS2_k127_665033_5 - - - - 0.000000000000000000000000000000000001393 148.0
MMS2_k127_665033_6 KR domain K13774 - - 0.0001651 44.0
MMS2_k127_668543_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 4.436e-195 620.0
MMS2_k127_668543_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 5.055e-195 612.0
MMS2_k127_668543_10 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 287.0
MMS2_k127_668543_11 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000001488 218.0
MMS2_k127_668543_12 DUF72 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001063 216.0
MMS2_k127_668543_13 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000003428 168.0
MMS2_k127_668543_14 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000003727 162.0
MMS2_k127_668543_15 Methionine synthase II (cobalamin-independent) K00549 - 2.1.1.14 0.00000000000000000000000000000000000242 149.0
MMS2_k127_668543_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000003401 113.0
MMS2_k127_668543_17 lactate metabolic process - - - 0.00000000000000000005496 96.0
MMS2_k127_668543_18 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000001644 55.0
MMS2_k127_668543_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 539.0
MMS2_k127_668543_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 502.0
MMS2_k127_668543_4 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 512.0
MMS2_k127_668543_5 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 445.0
MMS2_k127_668543_6 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 417.0
MMS2_k127_668543_7 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 356.0
MMS2_k127_668543_8 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 330.0
MMS2_k127_668543_9 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 323.0
MMS2_k127_67833_0 Uncharacterized protein family (UPF0051) K09014 - - 3.586e-254 789.0
MMS2_k127_67833_1 ATPases associated with a variety of cellular activities K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 351.0
MMS2_k127_67833_2 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000002162 93.0
MMS2_k127_689051_0 to SP P29212 GB L02649 GB X70994 PID 581070 GB U00096 percent identity K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 494.0
MMS2_k127_689051_1 Peptidase family M13 K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 434.0
MMS2_k127_689051_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000002969 198.0
MMS2_k127_689051_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000007958 191.0
MMS2_k127_689051_4 ribosomal small subunit binding - - - 0.000000000000000000000000000000000000408 148.0
MMS2_k127_697261_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000000000000000307 229.0
MMS2_k127_697261_1 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000002878 157.0
MMS2_k127_697261_2 DNA binding K06875 - - 0.000000000000000000000000000000004856 130.0
MMS2_k127_697261_3 Membrane protein of 12 TMs K07087 - - 0.000000000000000000000000000002977 135.0
MMS2_k127_697261_4 structural constituent of ribosome K02910 - - 0.0000000000000000000000002814 107.0
MMS2_k127_697261_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.0000000000000001579 82.0
MMS2_k127_697261_6 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.000000000000004737 76.0
MMS2_k127_699857_0 Aminotransferase class-III K00823 - 2.6.1.19 3.913e-199 629.0
MMS2_k127_699857_1 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 342.0
MMS2_k127_699857_2 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 314.0
MMS2_k127_699857_3 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001563 255.0
MMS2_k127_699857_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000003706 241.0
MMS2_k127_699857_5 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000001167 239.0
MMS2_k127_699857_6 Archaeal holliday junction resolvase (hjc) - - - 0.000000000000000000000000000000000000000000000003056 178.0
MMS2_k127_699857_7 - - - - 0.00000000000000000000000000000000000000000005339 162.0
MMS2_k127_699857_8 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000005823 88.0
MMS2_k127_740519_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 475.0
MMS2_k127_740519_1 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 380.0
MMS2_k127_740519_2 NMD3 family K07562 - - 0.0000000000000000000000000000000002881 144.0
MMS2_k127_740519_3 structural constituent of ribosome K02984 - - 0.00000000000000000000001755 101.0
MMS2_k127_795566_0 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 345.0
MMS2_k127_795566_1 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
MMS2_k127_795566_2 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000001428 249.0
MMS2_k127_795566_3 Protein of unknown function (DUF359) K09735 - - 0.00000000000000000000000000000000000000000001671 168.0
MMS2_k127_795566_4 structural constituent of ribosome K02974 - - 0.00000000000000000000000000001001 121.0
MMS2_k127_795566_5 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000001165 86.0
MMS2_k127_795566_6 DDE superfamily endonuclease - - - 0.00000000000000001105 84.0
MMS2_k127_795566_7 DDE superfamily endonuclease - - - 0.0000000003429 65.0
MMS2_k127_795566_8 - - - - 0.0009013 51.0
MMS2_k127_79724_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 504.0
MMS2_k127_79724_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000001924 203.0
MMS2_k127_79724_2 Cysteine synthase K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000351 203.0
MMS2_k127_79724_3 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000009827 184.0
MMS2_k127_79724_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000001271 158.0
MMS2_k127_79724_5 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000004653 113.0
MMS2_k127_79724_6 Required for chromosome condensation and partitioning K03529 - - 0.00000000002042 64.0
MMS2_k127_810119_0 transferase activity, transferring acyl groups K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 608.0
MMS2_k127_810119_1 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 438.0
MMS2_k127_810119_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 336.0
MMS2_k127_810119_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000000001163 203.0
MMS2_k127_810119_4 2-phosphosulfolactate phosphatase activity K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000002969 178.0
MMS2_k127_810119_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000002555 139.0
MMS2_k127_810119_6 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.00000000000000000000000002316 117.0
MMS2_k127_810119_7 - - - - 0.000000000000000000000002551 103.0
MMS2_k127_823923_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 358.0
MMS2_k127_823923_1 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000002003 244.0
MMS2_k127_823923_2 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000001764 122.0
MMS2_k127_823923_3 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000003951 92.0
MMS2_k127_823923_4 pfam nudix - - - 0.00000000000000000001009 98.0
MMS2_k127_823923_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000001952 71.0
MMS2_k127_831984_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 1.506e-276 858.0
MMS2_k127_831984_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.281e-238 757.0
MMS2_k127_831984_10 - - - - 0.000000000000002595 83.0
MMS2_k127_831984_11 SRP19 protein K03105 - - 0.00000001208 60.0
MMS2_k127_831984_12 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 0.0000005674 56.0
MMS2_k127_831984_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 581.0
MMS2_k127_831984_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 567.0
MMS2_k127_831984_4 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000008481 217.0
MMS2_k127_831984_5 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000003936 187.0
MMS2_k127_831984_6 structural constituent of ribosome K02995 - - 0.000000000000000000000000000000000000005109 149.0
MMS2_k127_831984_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000001783 117.0
MMS2_k127_831984_8 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000005116 119.0
MMS2_k127_831984_9 FR47-like protein - - - 0.0000000000000000338 92.0
MMS2_k127_852366_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 531.0
MMS2_k127_852366_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 525.0
MMS2_k127_852366_10 Prolyl oligopeptidase family K01322 - 3.4.21.26 0.000000000000000000000000000000003929 142.0
MMS2_k127_852366_13 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000002311 61.0
MMS2_k127_852366_14 Hemerythrin HHE cation binding domain - - - 0.000000003314 64.0
MMS2_k127_852366_2 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 477.0
MMS2_k127_852366_3 Pantothenic acid kinase K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 386.0
MMS2_k127_852366_4 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 329.0
MMS2_k127_852366_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 336.0
MMS2_k127_852366_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 318.0
MMS2_k127_852366_7 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 301.0
MMS2_k127_852366_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007734 284.0
MMS2_k127_852366_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000101 248.0
MMS2_k127_882630_0 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 442.0
MMS2_k127_882630_1 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 386.0
MMS2_k127_882630_10 protein conserved in archaea K09714 - - 0.000000000155 67.0
MMS2_k127_882630_11 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0003245 49.0
MMS2_k127_882630_2 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 378.0
MMS2_k127_882630_3 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 325.0
MMS2_k127_882630_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 312.0
MMS2_k127_882630_5 ABC-type molybdate transport system periplasmic K15495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002536 259.0
MMS2_k127_882630_6 PFAM binding-protein-dependent transport systems inner membrane component K15496 - - 0.00000000000000000000000000000000000000000000000000000002044 206.0
MMS2_k127_882630_7 ABC transporter K15497 - 3.6.3.55 0.00000000000000000000000000000000002003 143.0
MMS2_k127_882630_8 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000001301 127.0
MMS2_k127_882630_9 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000003436 109.0
MMS2_k127_905751_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 556.0
MMS2_k127_905751_1 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000001836 120.0
MMS2_k127_905751_2 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000004613 81.0
MMS2_k127_911564_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 496.0
MMS2_k127_911564_1 Peptidyl-prolyl cis-trans K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000009121 240.0
MMS2_k127_911564_2 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000004483 228.0
MMS2_k127_911564_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000006874 183.0
MMS2_k127_911564_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000002203 173.0
MMS2_k127_911564_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000000000003354 115.0
MMS2_k127_911564_6 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001191 98.0
MMS2_k127_911564_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000001292 96.0
MMS2_k127_911564_8 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.0000003048 60.0
MMS2_k127_933556_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 467.0
MMS2_k127_933556_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 402.0
MMS2_k127_933556_2 NAD-dependent epimerase dehydratase K01784,K03274 - 5.1.3.2,5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 343.0
MMS2_k127_933556_3 COG1290 Cytochrome b subunit of the bc complex K15879 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009227 260.0
MMS2_k127_933556_4 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000008598 244.0
MMS2_k127_933556_5 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
MMS2_k127_933556_6 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000004171 204.0
MMS2_k127_933556_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000263 152.0
MMS2_k127_933556_8 Protein of unknown function (DUF1634) - - - 0.0000000000000000000000000004135 117.0
MMS2_k127_991315_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 476.0
MMS2_k127_991315_1 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000001072 256.0
MMS2_k127_991315_2 C-terminal AAA-associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000005775 220.0
MMS2_k127_991315_3 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000001015 98.0
MMS2_k127_991315_4 Protein of unknown function (DUF3311) - - - 0.000000000002345 70.0