Overview

ID MAG03161
Name PYH1_bin.58
Sample SMP0073
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order TCS64
Family TCS64
Genus UBA8941
Species
Assembly information
Completeness (%) 67.01
Contamination (%) 2.49
GC content (%) 36.0
N50 (bp) 2,954
Genome size (bp) 1,118,148

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1184

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1001627_0 Major facilitator superfamily - - - 0.0000001104 61.0
PYH1_k127_1002557_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.618e-194 614.0
PYH1_k127_1002557_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000002787 130.0
PYH1_k127_1002557_2 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.0001282 46.0
PYH1_k127_1027470_0 Zinc carboxypeptidase K14054 - - 3.499e-250 797.0
PYH1_k127_1027470_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 402.0
PYH1_k127_1027470_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 337.0
PYH1_k127_1027470_3 DNA primase K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003793 276.0
PYH1_k127_1031865_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 502.0
PYH1_k127_1044469_0 Pyruvate formate lyase-like K00656 - 2.3.1.54 7.379e-245 768.0
PYH1_k127_1044469_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 447.0
PYH1_k127_1044469_2 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 319.0
PYH1_k127_1044469_3 KR domain K00059 - 1.1.1.100 0.000000000000002413 80.0
PYH1_k127_1076181_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000006624 234.0
PYH1_k127_1076181_1 TIGRFAM thioredoxin K03671 - - 0.0000000000000000000000000000009528 124.0
PYH1_k127_1076181_2 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000002765 116.0
PYH1_k127_1076181_3 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000003555 75.0
PYH1_k127_1077190_0 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 308.0
PYH1_k127_1077190_1 Peptidase family M28 - - - 0.0000007504 55.0
PYH1_k127_1077190_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000002346 54.0
PYH1_k127_107934_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 362.0
PYH1_k127_107934_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 305.0
PYH1_k127_107934_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0003674,GO:0003824,GO:0004764,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0055114,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000001904 226.0
PYH1_k127_107934_3 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000002375 99.0
PYH1_k127_1116127_0 GMP synthase, glutamine-hydrolyzing K01951 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 277.0
PYH1_k127_1116127_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000797 197.0
PYH1_k127_1117165_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 299.0
PYH1_k127_1117165_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000002861 235.0
PYH1_k127_1117165_2 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000006569 196.0
PYH1_k127_1117165_3 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0001393 44.0
PYH1_k127_112354_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 609.0
PYH1_k127_112354_1 PFAM Metal-dependent phosphohydrolase, HD K06950 - - 0.0000000000000000000000000000000000002474 147.0
PYH1_k127_112354_2 Methyltransferase domain - - - 0.000000000000009683 81.0
PYH1_k127_112354_3 Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4 U6 di-snRNP, spliceosomal U4 U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4 U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity) K12625 GO:0000375,GO:0000377,GO:0000398,GO:0000932,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005688,GO:0005730,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0022613,GO:0030490,GO:0030532,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0035770,GO:0036464,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045292,GO:0046483,GO:0046540,GO:0070013,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097525,GO:0097526,GO:0120114,GO:0120115,GO:1901360,GO:1901363,GO:1990726,GO:1990904 - 0.00000000002432 68.0
PYH1_k127_1136005_0 glycosyl transferase family 2 K00786 - - 0.0000000000000000000000000000002155 132.0
PYH1_k127_115751_0 Peptidase S9 prolyl oligopeptidase active site - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006559 244.0
PYH1_k127_115751_1 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000000000000000001389 194.0
PYH1_k127_115751_2 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000002178 199.0
PYH1_k127_118594_0 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000006011 113.0
PYH1_k127_118594_1 Belongs to the thioredoxin family K03671,K05838 - - 0.00000000000003386 77.0
PYH1_k127_1224758_0 Mandelate racemase muconate lactonizing enzyme K01683 - 4.2.1.5 0.000000000000000000000000000000000000000000000000000006631 204.0
PYH1_k127_1224758_1 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000006636 87.0
PYH1_k127_1232945_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 340.0
PYH1_k127_1232945_2 - - - - 0.00000000000000000000000000000000000000002137 165.0
PYH1_k127_1232945_3 phosphatase activity K07025,K08723 - 3.1.3.5 0.0000000001558 63.0
PYH1_k127_1232945_4 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool K01091 - 3.1.3.18 0.0001088 45.0
PYH1_k127_1233712_0 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000003575 207.0
PYH1_k127_1233712_1 retrograde transport, endosome to Golgi - - - 0.00000000000000000000000000001946 123.0
PYH1_k127_1233712_2 acetyltransferase - - - 0.000001311 56.0
PYH1_k127_127422_0 synthetase K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 578.0
PYH1_k127_127422_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 514.0
PYH1_k127_127422_2 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 512.0
PYH1_k127_127422_3 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 353.0
PYH1_k127_127422_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000004689 203.0
PYH1_k127_1284034_0 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 339.0
PYH1_k127_1284034_1 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000001535 209.0
PYH1_k127_1284034_2 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000147 169.0
PYH1_k127_1284034_3 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000001436 128.0
PYH1_k127_1284034_4 AAA-like domain K06915 - - 0.00000000005646 70.0
PYH1_k127_1292333_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000001709 260.0
PYH1_k127_1292333_1 Ser thr protein kinase K07176 - - 0.00000000000000000000000000000000000000000000000000001434 197.0
PYH1_k127_1293715_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002349 200.0
PYH1_k127_1293715_1 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000157 111.0
PYH1_k127_1293715_2 PFAM Rubredoxin - - - 0.0000000000000000000002477 96.0
PYH1_k127_1293715_3 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001395 78.0
PYH1_k127_1293715_4 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000001114 75.0
PYH1_k127_1293715_5 protein conserved in archaea K09723 - - 0.000000009088 59.0
PYH1_k127_131375_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 375.0
PYH1_k127_131375_1 Aminotransferase class I and II - - - 0.00000000000006029 77.0
PYH1_k127_134779_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000001385 171.0
PYH1_k127_134779_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000001131 114.0
PYH1_k127_1412229_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000008333 139.0
PYH1_k127_1412229_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000003328 103.0
PYH1_k127_1412229_2 Mycolic acid cyclopropane synthetase - - - 0.000000003603 64.0
PYH1_k127_150295_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 394.0
PYH1_k127_150295_1 TIGRFAM UbiD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 318.0
PYH1_k127_150295_2 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000006413 158.0
PYH1_k127_1540509_0 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 314.0
PYH1_k127_1540509_1 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000000000005704 193.0
PYH1_k127_1540509_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.000000000000000000000000000000001134 135.0
PYH1_k127_1545795_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 355.0
PYH1_k127_1545795_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 300.0
PYH1_k127_1545795_2 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000001209 194.0
PYH1_k127_1549742_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000002722 246.0
PYH1_k127_1549742_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000001259 242.0
PYH1_k127_1563799_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 9.153e-266 837.0
PYH1_k127_1563799_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000003352 195.0
PYH1_k127_1563799_2 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000001833 169.0
PYH1_k127_1586691_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 304.0
PYH1_k127_159460_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000005609 239.0
PYH1_k127_1597253_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 538.0
PYH1_k127_1597253_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001855 260.0
PYH1_k127_1597253_2 Domain of unknown function (DUF4438) - - - 0.00000000000000000000000000000000000000000000000000000000000000001172 234.0
PYH1_k127_1597253_3 Domain of unknown function (DUF4438) - - - 0.00000000000000000000000000000000000000000000000000000006149 206.0
PYH1_k127_1597253_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000002709 92.0
PYH1_k127_1597253_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000002551 67.0
PYH1_k127_1604003_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 428.0
PYH1_k127_1604003_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 322.0
PYH1_k127_1604003_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000005766 71.0
PYH1_k127_1609502_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000006833 174.0
PYH1_k127_1609502_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000003844 141.0
PYH1_k127_1610356_0 protein conserved in bacteria K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000005442 244.0
PYH1_k127_1610356_1 protein secretion K15125 - - 0.00000000000001853 73.0
PYH1_k127_1615058_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 7.435e-202 645.0
PYH1_k127_1618138_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 1.269e-197 637.0
PYH1_k127_1634259_0 PFAM Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000003586 189.0
PYH1_k127_1634259_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000001947 151.0
PYH1_k127_1634259_2 PFAM Nitroreductase K04719 - 1.13.11.79 0.0000000000000001156 88.0
PYH1_k127_1641954_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 402.0
PYH1_k127_1641954_1 Folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000007378 141.0
PYH1_k127_1647117_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 462.0
PYH1_k127_1647117_1 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 316.0
PYH1_k127_1647117_2 DNA polymerase Ligase (LigD) K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000009946 192.0
PYH1_k127_1647117_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000005093 176.0
PYH1_k127_1647117_4 DNA polymerase Ligase (LigD) K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000001105 174.0
PYH1_k127_1647117_5 DNA polymerase LigD, polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000005474 118.0
PYH1_k127_1647117_6 Succinate dehydrogenase fumarate reductase flavoprotein K00394 - 1.8.99.2 0.000000000000001261 79.0
PYH1_k127_1660933_0 MutL protein - - - 4.896e-198 634.0
PYH1_k127_1660933_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 338.0
PYH1_k127_1660933_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000001255 253.0
PYH1_k127_1660933_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000001543 234.0
PYH1_k127_1660933_4 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000002884 180.0
PYH1_k127_1660933_5 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000007231 111.0
PYH1_k127_1660933_6 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000002701 89.0
PYH1_k127_1663206_0 Diphthamide K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000001751 239.0
PYH1_k127_1663206_1 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000003422 187.0
PYH1_k127_1663206_2 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001545 153.0
PYH1_k127_1663206_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000002207 96.0
PYH1_k127_1663206_4 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000007484 94.0
PYH1_k127_1663206_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000003696 91.0
PYH1_k127_1663206_6 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000126 52.0
PYH1_k127_1679355_0 Belongs to the UPF0200 family - - - 0.0000000000000000000000000000000000000000001511 165.0
PYH1_k127_1679355_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K03885,K17870 - 1.6.3.3,1.6.99.3 0.000000000000000000000000000000000002569 143.0
PYH1_k127_1679355_2 Belongs to the UPF0201 family K09736 - - 0.0000000005706 65.0
PYH1_k127_1681918_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000003879 137.0
PYH1_k127_1681918_1 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000004539 129.0
PYH1_k127_1681918_2 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000001604 108.0
PYH1_k127_1681918_3 - - - - 0.0001659 47.0
PYH1_k127_169517_0 Diguanylate cyclase K20959,K20964 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032879,GO:0040012,GO:0040013,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146 2.7.7.65,3.1.4.52 0.000000000000002213 81.0
PYH1_k127_169517_1 PAS domain K03776 - - 0.0000000000104 70.0
PYH1_k127_1707818_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000002438 230.0
PYH1_k127_1709866_0 Major facilitator superfamily K08223 - - 0.0000000000003872 81.0
PYH1_k127_1709866_1 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000003052 51.0
PYH1_k127_1710909_0 Uncharacterised protein family (UPF0182) K09118 - - 0.000000000004504 79.0
PYH1_k127_1712079_1 LPP20 lipoprotein - - - 0.0000000000000000001811 97.0
PYH1_k127_1714294_0 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000003674 238.0
PYH1_k127_1714294_1 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000000000000000000000005868 111.0
PYH1_k127_1714294_2 - - - - 0.0000000000000000000002171 105.0
PYH1_k127_1714294_3 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000002073 80.0
PYH1_k127_1723139_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002672 265.0
PYH1_k127_1723139_1 Transcriptional regulator - - - 0.0000001114 60.0
PYH1_k127_1723808_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.094e-215 685.0
PYH1_k127_1723808_1 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000002109 231.0
PYH1_k127_1723808_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000008036 205.0
PYH1_k127_1723808_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000002594 179.0
PYH1_k127_1723808_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000006905 155.0
PYH1_k127_1723808_5 Glycine cleavage H-protein K02437 - - 0.000000000000000000000000000000000006339 142.0
PYH1_k127_1723808_6 ThiS family - - - 0.00002496 49.0
PYH1_k127_1728163_0 SnoaL-like polyketide cyclase - - - 0.0000000000000007912 82.0
PYH1_k127_1735267_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
PYH1_k127_1735267_1 dehydratase - - - 0.00004395 54.0
PYH1_k127_1745622_0 Flavodoxin - - - 0.00000000000000000000000000000000000008784 147.0
PYH1_k127_1745622_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000001671 157.0
PYH1_k127_1761135_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001669 271.0
PYH1_k127_1761135_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000005831 143.0
PYH1_k127_1832293_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 1.199e-284 893.0
PYH1_k127_1832293_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000001233 199.0
PYH1_k127_1837744_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000009441 269.0
PYH1_k127_1837744_1 - - - - 0.000000000000000000000000000000000000009433 157.0
PYH1_k127_1837744_2 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000003779 147.0
PYH1_k127_1839558_0 Fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944 - 0.0004861 48.0
PYH1_k127_1845687_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000003007 167.0
PYH1_k127_1845687_1 FMN binding K03809 - 1.6.5.2 0.000000000000000000000000000000000000002412 151.0
PYH1_k127_1845687_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000005273 148.0
PYH1_k127_1845687_3 - - - - 0.000000000000000000000000000002722 124.0
PYH1_k127_1856844_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.198e-215 686.0
PYH1_k127_1914076_0 Gamma-glutamyltranspeptidase 2-like K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 566.0
PYH1_k127_1914076_1 Peptidase, S9A B C family, catalytic domain protein K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 350.0
PYH1_k127_1942203_0 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 386.0
PYH1_k127_1942203_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 356.0
PYH1_k127_1942203_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000001879 123.0
PYH1_k127_1942203_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000002025 118.0
PYH1_k127_1942203_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0002299 47.0
PYH1_k127_2001823_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002527 283.0
PYH1_k127_2001823_1 PFAM Glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000001961 209.0
PYH1_k127_2001823_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000003592 211.0
PYH1_k127_2001823_3 GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.000000000000003649 79.0
PYH1_k127_2042423_0 kinase activity K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000000002271 182.0
PYH1_k127_2042423_1 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K14155 - 4.4.1.8 0.000000000000000000000000000000000000000007175 167.0
PYH1_k127_2054865_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 3.674e-194 617.0
PYH1_k127_2054865_1 Alanyl-tRNA synthetase K01872 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 6.1.1.7 0.0000000000000000000000000000000000000000000000000006314 187.0
PYH1_k127_2054865_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.00000000000000000000000000000000000000000000000002668 184.0
PYH1_k127_2054865_3 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.0000000001223 71.0
PYH1_k127_2054865_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000776 48.0
PYH1_k127_2055638_0 Dehydrogenase K00111,K15736 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 380.0
PYH1_k127_2055638_1 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000005639 235.0
PYH1_k127_2055638_2 PFAM CBS domain containing protein - - - 0.0000000000000000001495 93.0
PYH1_k127_2055638_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000003937 61.0
PYH1_k127_2055638_4 TM2 domain - - - 0.000000004419 62.0
PYH1_k127_2062521_0 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 469.0
PYH1_k127_2062521_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 304.0
PYH1_k127_2062521_2 phosphatase activity K07025,K08723 - 3.1.3.5 0.00000000000000000000000000000000000000009195 154.0
PYH1_k127_2083583_0 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000001248 203.0
PYH1_k127_2087254_0 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000001268 106.0
PYH1_k127_2095803_0 Belongs to the UPF0273 family - - - 0.00000000000000000000000000000005238 134.0
PYH1_k127_2095803_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000001187 119.0
PYH1_k127_2124416_0 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 417.0
PYH1_k127_2131465_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000177 183.0
PYH1_k127_2131465_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000004523 162.0
PYH1_k127_2131465_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000001094 110.0
PYH1_k127_2131465_3 - K00960 - 2.7.7.6 0.00000000000000000001877 91.0
PYH1_k127_2131674_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 5.769e-201 641.0
PYH1_k127_2131674_1 - - - - 0.000000000000007679 76.0
PYH1_k127_2131674_2 DNA-binding transcription factor activity - - - 0.000000000000411 79.0
PYH1_k127_2131674_3 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.0001212 48.0
PYH1_k127_2151204_0 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000007181 212.0
PYH1_k127_2151204_1 Transport permease protein K01992 - - 0.000000000016 73.0
PYH1_k127_2151204_2 Amidohydrolase family K06015 - 3.5.1.81 0.000006437 49.0
PYH1_k127_2156528_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 344.0
PYH1_k127_2156528_1 Catalyzes the ATP-dependent phosphorylation of fructoselysine to fructoselysine 6-phosphate. Functions in a fructoselysine degradation pathway that allows E.coli to grow on fructoselysine or psicoselysine. To a much lesser extenst, is also able to phosphorylate psicoselysine K10710 GO:0003674,GO:0003824,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.218 0.000000000000000000000000000000000000000002011 164.0
PYH1_k127_2162102_0 Domain of unknown function (DUF4438) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004598 260.0
PYH1_k127_2162102_1 Conserved protein implicated in secretion - - - 0.000000000000000000000000000000000005372 144.0
PYH1_k127_2162102_2 Conserved protein implicated in secretion - - - 0.000000000003297 74.0
PYH1_k127_2172647_0 Psort location Cytoplasmic, score K01783 - 5.1.3.1 0.0000000000000000000000000711 111.0
PYH1_k127_2172647_1 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.0000000000000001112 85.0
PYH1_k127_2175128_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 452.0
PYH1_k127_2175128_1 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000001191 201.0
PYH1_k127_2175128_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000009121 189.0
PYH1_k127_2175128_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00005604 53.0
PYH1_k127_2186460_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 382.0
PYH1_k127_2186460_1 membrane K07149 - - 0.000000000000000000000000000000000000000000000000000000000001504 216.0
PYH1_k127_2186460_2 CoA binding domain K06929 - - 0.00000000000000000000000000000000007206 137.0
PYH1_k127_2186460_3 Archaeal Nre, N-terminal - - - 0.000000000000000000000000003443 115.0
PYH1_k127_2191767_0 Domain of unknown function (DUF5117) - - - 2.093e-234 744.0
PYH1_k127_2191767_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000004243 106.0
PYH1_k127_2191767_2 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.0000000299 60.0
PYH1_k127_220060_0 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 359.0
PYH1_k127_220060_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000006471 181.0
PYH1_k127_220060_2 Protein conserved in bacteria - - - 0.0000000000000001447 85.0
PYH1_k127_2204444_0 in RNase L inhibitor, RLI K06174 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 606.0
PYH1_k127_2204444_1 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 424.0
PYH1_k127_2211997_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002299 266.0
PYH1_k127_2211997_1 COG1921 Selenocysteine synthase seryl-tRNASer selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000002878 196.0
PYH1_k127_2214055_0 OsmC-like protein - - - 0.0000000000000000000000000000000000007225 143.0
PYH1_k127_2214055_1 DGC domain - - - 0.00000000000000000000000000006646 120.0
PYH1_k127_2214055_2 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000001787 117.0
PYH1_k127_2214055_3 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.000000000000000000000000003996 114.0
PYH1_k127_2214055_4 DGC domain - - - 0.00000000000000000000000005552 111.0
PYH1_k127_231736_0 Archaeal Type IV pilin, N-terminal - - - 0.0000000000000000724 90.0
PYH1_k127_2430190_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K18020 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0043546,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363 1.2.5.3,1.2.99.8 1.008e-199 647.0
PYH1_k127_2430190_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 412.0
PYH1_k127_2430190_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein - - - 0.0000000000000000000000000000000000000000000000000000000086 209.0
PYH1_k127_2430190_3 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000002792 193.0
PYH1_k127_2430190_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000003021 180.0
PYH1_k127_2430190_5 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000003901 163.0
PYH1_k127_2430190_6 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000005945 152.0
PYH1_k127_2430190_7 Guanylyl transferase CofC like K07141 - 2.7.7.76 0.000000000000000000000007623 108.0
PYH1_k127_2430190_8 Transcriptional regulator - - - 0.000000000000000007569 83.0
PYH1_k127_2432934_0 DNA polymerase K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 570.0
PYH1_k127_2432934_1 nucleic acid binding OB-fold tRNA helicase-type K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000005909 268.0
PYH1_k127_2447662_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000005367 235.0
PYH1_k127_2447662_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000644 187.0
PYH1_k127_2447662_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000465 89.0
PYH1_k127_2453741_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 333.0
PYH1_k127_2453741_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004501 301.0
PYH1_k127_2453741_2 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000004715 158.0
PYH1_k127_2453741_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000001768 93.0
PYH1_k127_2495382_0 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000002396 109.0
PYH1_k127_2495382_1 - - - - 0.0000000392 63.0
PYH1_k127_2495382_2 - - - - 0.00001942 54.0
PYH1_k127_2502809_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001362 276.0
PYH1_k127_2502809_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000007215 204.0
PYH1_k127_2502809_2 nitric oxide - - - 0.000000000000000000000002731 102.0
PYH1_k127_2508873_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007162 256.0
PYH1_k127_2508873_1 ABC-2 family transporter protein - - - 0.000000000000000000007122 96.0
PYH1_k127_2508873_2 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.000000000000009593 76.0
PYH1_k127_2508873_3 Transporter, major facilitator family protein K08223 - - 0.00000000000007921 83.0
PYH1_k127_2521939_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 326.0
PYH1_k127_2521939_1 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 275.0
PYH1_k127_2521939_2 Domain of unknown function (DUF2437) - - - 0.00000000000001758 76.0
PYH1_k127_2528519_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000001896 207.0
PYH1_k127_2528519_1 D-amino acid K00285 - 1.4.5.1 0.00000000009229 64.0
PYH1_k127_2528519_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000363 55.0
PYH1_k127_2528519_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0003146 50.0
PYH1_k127_2546264_0 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 316.0
PYH1_k127_2546264_1 FtsX-like permease family - - - 0.000000000000000000000000001985 119.0
PYH1_k127_2546264_2 ammonia-lyase activity K12235 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003941,GO:0005488,GO:0005509,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016594,GO:0016597,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017076,GO:0017144,GO:0018114,GO:0019752,GO:0019842,GO:0019904,GO:0022607,GO:0030165,GO:0030170,GO:0030378,GO:0030554,GO:0030848,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036361,GO:0036477,GO:0042165,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044297,GO:0044424,GO:0044464,GO:0045177,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0046983,GO:0047661,GO:0048037,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:0097458,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 5.1.1.18 0.000000000000000001863 87.0
PYH1_k127_2546264_3 aminopeptidase activity - - - 0.0000000000008332 80.0
PYH1_k127_2550428_0 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 359.0
PYH1_k127_2550428_1 Serine aminopeptidase, S33 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001485 52.0
PYH1_k127_2550951_0 MutL protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 295.0
PYH1_k127_2550951_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000009081 72.0
PYH1_k127_2569167_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.0000000000000000000000000000000000000000000000000000004727 201.0
PYH1_k127_2569167_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000004187 177.0
PYH1_k127_2569167_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000005497 177.0
PYH1_k127_2569167_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000002719 152.0
PYH1_k127_2569167_4 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000003857 124.0
PYH1_k127_2569167_5 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000005047 103.0
PYH1_k127_2569167_6 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000003607 70.0
PYH1_k127_2570861_0 myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000004617 218.0
PYH1_k127_2570861_1 ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000001598 200.0
PYH1_k127_2570861_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.0000000000000000000000000000000000000007789 153.0
PYH1_k127_257254_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 568.0
PYH1_k127_257254_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002978 290.0
PYH1_k127_257254_2 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000006068 82.0
PYH1_k127_257254_3 - - - - 0.00001205 55.0
PYH1_k127_2598821_0 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000000000000000007843 229.0
PYH1_k127_2604409_0 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 542.0
PYH1_k127_2604409_1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000008497 134.0
PYH1_k127_2605554_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
PYH1_k127_2605554_1 Acetyl xylan esterase (AXE1) K01303 - 3.4.19.1 0.000000000000000000000000000000004722 128.0
PYH1_k127_2639170_0 Baseplate J family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 469.0
PYH1_k127_2639170_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000005068 184.0
PYH1_k127_2639170_2 PAAR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000002888 175.0
PYH1_k127_2639170_3 cobalamin transport - - - 0.000000000000000000000000000000000000000000002318 171.0
PYH1_k127_2639170_4 Phage baseplate assembly protein W K06903 - - 0.00000000000000000000000000000000002225 139.0
PYH1_k127_2718076_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000001347 208.0
PYH1_k127_2718076_1 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000001912 185.0
PYH1_k127_2718076_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000003939 179.0
PYH1_k127_2718076_3 - - - - 0.00000000000000000000000000000000001116 145.0
PYH1_k127_2741064_0 DNA polymerase beta domain protein region K07073 - - 0.0000000000000000000000000000000000000000000000000000000006472 209.0
PYH1_k127_2741064_1 PFAM peptidase M50 - - - 0.00000000000000000000000936 111.0
PYH1_k127_2741064_2 DNA primase K02316 - - 0.0000000000000000000000119 105.0
PYH1_k127_2741064_3 NurA - - - 0.0000006176 57.0
PYH1_k127_2742852_0 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05580 - 1.6.5.3 0.00000000000000000000003807 105.0
PYH1_k127_2742852_1 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.00000000000000000000004574 108.0
PYH1_k127_2742852_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000002614 100.0
PYH1_k127_2742852_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000001134 74.0
PYH1_k127_2742852_4 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00005305 49.0
PYH1_k127_2838258_0 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 542.0
PYH1_k127_2838258_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000002018 158.0
PYH1_k127_2838258_3 Cytochrome c - - - 0.00000000000000000000000002416 109.0
PYH1_k127_2845458_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 346.0
PYH1_k127_2845458_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 314.0
PYH1_k127_2845458_2 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000003816 170.0
PYH1_k127_2845458_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000163 163.0
PYH1_k127_2845458_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000112 141.0
PYH1_k127_2845458_5 Nitroreductase family - - - 0.00000000000003796 75.0
PYH1_k127_2845458_6 Major Facilitator Superfamily - - - 0.00001064 57.0
PYH1_k127_2845458_7 Cupin domain - - - 0.00003329 51.0
PYH1_k127_296022_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000941 265.0
PYH1_k127_296022_1 PFAM SNARE associated Golgi protein - - - 0.0000000001828 65.0
PYH1_k127_300313_0 Plug domain of Sec61p K10956 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002494 258.0
PYH1_k127_300313_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008136 207.0
PYH1_k127_300313_2 ribosomal protein K02907 - - 0.0000000000000000000000000000000000000003485 153.0
PYH1_k127_300313_3 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000465 121.0
PYH1_k127_3091713_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000006828 251.0
PYH1_k127_3091713_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000001779 229.0
PYH1_k127_3091713_2 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000001906 170.0
PYH1_k127_3091713_3 Pfam:DUF39 - - - 0.0000000000000000000000000000000000001752 145.0
PYH1_k127_3091713_4 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000000000000000000000000008242 116.0
PYH1_k127_3091713_5 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000001045 110.0
PYH1_k127_310945_0 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000004206 268.0
PYH1_k127_310945_1 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.0000000000000000000000000000000001101 140.0
PYH1_k127_310945_2 PFAM Radical SAM domain protein K01012 - 2.8.1.6 0.00000000000000004447 82.0
PYH1_k127_310945_3 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000125 68.0
PYH1_k127_3144080_0 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000007371 163.0
PYH1_k127_3144080_1 flavodoxin K00230 - 1.3.5.3 0.0000000000000000000000001147 114.0
PYH1_k127_3144080_2 Rhodanese Homology Domain - - - 0.00000000000000000001361 96.0
PYH1_k127_3216019_0 - - - - 0.0007079 51.0
PYH1_k127_3221087_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 300.0
PYH1_k127_3221087_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.0000000000000000000000000000000000000000000000000006917 187.0
PYH1_k127_3221087_2 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000002604 166.0
PYH1_k127_3221087_3 GTPase of K06942 - - 0.00000000000000000000000000000000000000000138 158.0
PYH1_k127_3221087_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000005003 108.0
PYH1_k127_3229861_0 E1-E2 ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 355.0
PYH1_k127_3229861_1 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000001531 128.0
PYH1_k127_3252163_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 419.0
PYH1_k127_3252163_1 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.0000000000000000000000000005756 117.0
PYH1_k127_3252163_2 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000002267 115.0
PYH1_k127_3252163_3 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000005159 84.0
PYH1_k127_3256372_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 306.0
PYH1_k127_3256372_1 4Fe-4S dicluster domain K12143 - - 0.0000000000000000000682 94.0
PYH1_k127_3256372_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000005564 55.0
PYH1_k127_3256372_3 Belongs to the complex I subunit 6 family K05578 - 1.6.5.3 0.00002119 49.0
PYH1_k127_3272481_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 496.0
PYH1_k127_3272481_1 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000004554 92.0
PYH1_k127_3282338_0 Transposase domain (DUF772) K07481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 528.0
PYH1_k127_3294580_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000002273 232.0
PYH1_k127_3294580_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003635 222.0
PYH1_k127_3294580_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000008693 196.0
PYH1_k127_3308901_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 432.0
PYH1_k127_3308901_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000001443 226.0
PYH1_k127_3308901_2 Belongs to the aspartokinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000006485 120.0
PYH1_k127_3321022_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000003268 242.0
PYH1_k127_3321022_1 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000002271 101.0
PYH1_k127_3367826_0 Rhodanese-like domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 467.0
PYH1_k127_3436887_0 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000001558 204.0
PYH1_k127_3436887_1 - - - - 0.0000000000000000000009068 103.0
PYH1_k127_3443312_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 300.0
PYH1_k127_3443312_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000004136 199.0
PYH1_k127_3476217_0 PFAM peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 409.0
PYH1_k127_3476217_1 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000108 177.0
PYH1_k127_3476217_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000005713 177.0
PYH1_k127_3476217_3 enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.0000000000008578 71.0
PYH1_k127_3479768_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 386.0
PYH1_k127_3479768_1 - - - - 0.000000000000000000000000000000000000001729 150.0
PYH1_k127_3479768_2 PFAM Glycosyl transferase family 2 K00786 - - 0.0000000000000000003677 97.0
PYH1_k127_3479768_3 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.000000000000000003097 90.0
PYH1_k127_3511060_0 COG1032 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 358.0
PYH1_k127_3511060_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000111 118.0
PYH1_k127_353008_0 nudix family K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000001614 173.0
PYH1_k127_353008_1 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.000000000000000000000000000000000000000002369 164.0
PYH1_k127_353008_2 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.0000000000002445 78.0
PYH1_k127_3530440_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 408.0
PYH1_k127_3559129_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 407.0
PYH1_k127_3559129_1 formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000002392 168.0
PYH1_k127_3559129_2 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000008732 101.0
PYH1_k127_35675_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 408.0
PYH1_k127_35675_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000002015 212.0
PYH1_k127_35675_2 Zn-dependent protease with chaperone function K03799 - - 0.0000000000000000000000000000000000000000000000000002693 195.0
PYH1_k127_35675_3 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000003911 67.0
PYH1_k127_36369_0 proline dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 456.0
PYH1_k127_36369_1 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 351.0
PYH1_k127_36369_2 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001556 267.0
PYH1_k127_36369_3 PFAM regulatory protein AsnC Lrp family K03718 - - 0.0000000000000000000000000000000000000001855 154.0
PYH1_k127_36369_4 Transcriptional regulator - - - 0.000000000000000000000001243 111.0
PYH1_k127_3649086_0 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000007525 230.0
PYH1_k127_3649086_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000001795 178.0
PYH1_k127_3689995_0 - - - - 0.0000000000000000000000000000000000413 139.0
PYH1_k127_3689995_1 EXOIII K02342 - 2.7.7.7 0.0000000001393 64.0
PYH1_k127_3694958_0 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 361.0
PYH1_k127_3694958_1 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 327.0
PYH1_k127_3694958_2 Aminotransferase - - - 0.0000000000000000000000000000000000000001344 165.0
PYH1_k127_3694958_3 segregation and condensation protein K06024 - - 0.0000000000000000000000008586 111.0
PYH1_k127_3694958_4 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000001733 88.0
PYH1_k127_3733610_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.108e-238 749.0
PYH1_k127_3733610_1 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000007102 77.0
PYH1_k127_3733610_2 helix_turn_helix, Arsenical Resistance Operon Repressor K22043 - - 0.00000000004234 68.0
PYH1_k127_3737448_0 membrane-associated protein domain - - - 0.0001095 50.0
PYH1_k127_374011_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000002621 186.0
PYH1_k127_378668_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 621.0
PYH1_k127_378668_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001257 251.0
PYH1_k127_378668_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000001731 152.0
PYH1_k127_378668_3 metallochaperone-like domain - - - 0.00000000000003779 76.0
PYH1_k127_3792144_0 homocysteine catabolic process K01372 GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 496.0
PYH1_k127_37975_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 335.0
PYH1_k127_37975_1 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000008725 121.0
PYH1_k127_37975_2 ACT domain - - - 0.000000000000000000000000006018 117.0
PYH1_k127_37975_3 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products K03552 - 3.1.22.4 0.000000001543 62.0
PYH1_k127_3843534_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 389.0
PYH1_k127_3843534_1 2-phosphosulpholactate phosphatase - - - 0.0005081 44.0
PYH1_k127_3936812_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 329.0
PYH1_k127_3980561_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 358.0
PYH1_k127_3980561_1 - - - - 0.00000004477 57.0
PYH1_k127_3999489_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 385.0
PYH1_k127_3999489_1 segregation and condensation protein K06024 - - 0.000000000000000000000000003452 119.0
PYH1_k127_3999489_2 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000001539 113.0
PYH1_k127_3999489_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000003875 109.0
PYH1_k127_3999489_4 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000001783 79.0
PYH1_k127_3999489_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000003366 69.0
PYH1_k127_40320_0 - - - - 0.00000001702 63.0
PYH1_k127_4069564_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 338.0
PYH1_k127_4069564_1 PFAM methyltransferase small - - - 0.00000000000000000000000000000000000000000000003555 176.0
PYH1_k127_4069564_2 - - - - 0.000000000000000000000000000002245 126.0
PYH1_k127_4069564_3 PFAM CRS1 YhbY (CRM) domain K07574 - - 0.000000000000000002046 87.0
PYH1_k127_4069564_4 ASNC family K03718 - - 0.0000000000001252 76.0
PYH1_k127_4069564_5 Transcriptional regulator K03718 - - 0.00000000004339 70.0
PYH1_k127_4080878_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872,K07050 - 6.1.1.7 0.000000000000000000000000000002431 129.0
PYH1_k127_4080878_1 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000191 116.0
PYH1_k127_4080878_2 - - - - 0.000000000000001515 78.0
PYH1_k127_4085568_0 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000003555 193.0
PYH1_k127_4085568_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000001049 141.0
PYH1_k127_4085568_2 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000007236 132.0
PYH1_k127_4085568_3 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000003617 63.0
PYH1_k127_4085568_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000001842 56.0
PYH1_k127_4085568_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000309 55.0
PYH1_k127_4098659_0 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
PYH1_k127_4098659_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001621 253.0
PYH1_k127_4144090_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000003021 180.0
PYH1_k127_4144090_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000005387 162.0
PYH1_k127_4144090_2 ribonuclease activity K07060 - - 0.000000000000000000000000001068 118.0
PYH1_k127_417971_0 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001095 282.0
PYH1_k127_417971_1 PFAM peptidyl-prolyl cis-trans isomerase cyclophilin type K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000008279 181.0
PYH1_k127_417971_2 PFAM thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000001352 146.0
PYH1_k127_417971_3 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000005491 74.0
PYH1_k127_4188757_0 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 533.0
PYH1_k127_4188757_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 297.0
PYH1_k127_4188757_2 Major facilitator superfamily - - - 0.000000000000000006714 95.0
PYH1_k127_4240035_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000342 82.0
PYH1_k127_4240035_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000003032 63.0
PYH1_k127_4244231_0 FAD binding domain K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 1.611e-208 662.0
PYH1_k127_4244231_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 534.0
PYH1_k127_4244231_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 282.0
PYH1_k127_4244231_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000001911 102.0
PYH1_k127_4301705_0 Sterol carrier protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 317.0
PYH1_k127_4301705_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002868 252.0
PYH1_k127_4301705_2 Major Facilitator Superfamily - - - 0.000000000000000808 90.0
PYH1_k127_43077_0 hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000007877 145.0
PYH1_k127_43077_1 Belongs to the UPF0147 family K09721 - - 0.00000000000000000001603 94.0
PYH1_k127_43077_2 crossover junction endodeoxyribonuclease activity K01160 - 3.1.22.4 0.00000000000005617 77.0
PYH1_k127_43077_3 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000001012 80.0
PYH1_k127_4369639_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000318 268.0
PYH1_k127_4369639_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000005896 229.0
PYH1_k127_4369639_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000007164 211.0
PYH1_k127_4369639_3 COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit - - - 0.0000000000001977 82.0
PYH1_k127_4408360_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000518 251.0
PYH1_k127_4408360_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000003998 60.0
PYH1_k127_4413963_0 - - - - 0.00000000000000000000000000000000000000000000000000001396 195.0
PYH1_k127_4439885_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 357.0
PYH1_k127_4439885_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000002725 200.0
PYH1_k127_4439885_2 Transposase IS200 like K07491 - - 0.00001183 49.0
PYH1_k127_4439885_3 - - - - 0.0002006 48.0
PYH1_k127_444482_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - - 1.479e-274 865.0
PYH1_k127_444482_1 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000001181 229.0
PYH1_k127_4464535_0 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 391.0
PYH1_k127_4464535_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 302.0
PYH1_k127_4464535_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000165 178.0
PYH1_k127_4464535_3 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000008396 147.0
PYH1_k127_4464535_4 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000002414 142.0
PYH1_k127_4464535_5 PBP superfamily domain K05772 - - 0.00000000000000000000001661 104.0
PYH1_k127_4464535_6 PFAM molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.000000000007308 68.0
PYH1_k127_4464995_0 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001687 196.0
PYH1_k127_4464995_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000002314 188.0
PYH1_k127_4464995_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000911 168.0
PYH1_k127_4464995_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003847 160.0
PYH1_k127_4464995_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001247 102.0
PYH1_k127_4474777_0 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
PYH1_k127_4474777_1 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005438 226.0
PYH1_k127_4474777_2 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000001142 65.0
PYH1_k127_4541075_0 DEAD H associated K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 417.0
PYH1_k127_4541075_1 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000002183 220.0
PYH1_k127_4541075_2 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000323 209.0
PYH1_k127_4541075_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000003396 142.0
PYH1_k127_4541075_4 PFAM CBS domain containing protein - - - 0.0000000000000000000000000005989 120.0
PYH1_k127_458940_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000244 229.0
PYH1_k127_458940_1 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000131 198.0
PYH1_k127_463914_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 595.0
PYH1_k127_463914_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 467.0
PYH1_k127_463914_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 282.0
PYH1_k127_463914_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000104 148.0
PYH1_k127_463914_4 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000006002 130.0
PYH1_k127_463914_5 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001208 113.0
PYH1_k127_463914_6 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000008817 109.0
PYH1_k127_463914_7 4 iron, 4 sulfur cluster binding K00338 - 1.6.5.3 0.0000000003295 63.0
PYH1_k127_463914_8 Integral membrane protein DUF106 - - - 0.0000000005923 67.0
PYH1_k127_4658110_0 Zinc carboxypeptidase K14054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 546.0
PYH1_k127_4658110_1 - - - - 0.00000000000004385 73.0
PYH1_k127_466205_0 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000001044 179.0
PYH1_k127_466205_1 helix_turn_helix, mercury resistance K03713,K15580 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - 0.000000000003488 68.0
PYH1_k127_466205_2 PFAM Integrase catalytic region K07497 - - 0.000000003018 58.0
PYH1_k127_474168_0 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 404.0
PYH1_k127_4761544_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000009554 199.0
PYH1_k127_4761544_1 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.000000000000000000000000004346 115.0
PYH1_k127_4761544_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000001403 89.0
PYH1_k127_4761544_3 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.000002447 59.0
PYH1_k127_4877761_0 TIGRFAM anion transporter K03319,K11106 - - 0.000007433 56.0
PYH1_k127_4877761_1 PFAM glycosyl transferase family 2 K00721 - 2.4.1.83 0.0002091 52.0
PYH1_k127_494635_0 - - - - 0.000000000000623 73.0
PYH1_k127_494635_1 Transcriptional regulator - - - 0.000000000003752 76.0
PYH1_k127_494635_2 Domain of unknown function (DUF4382) - - - 0.000004449 53.0
PYH1_k127_496174_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
PYH1_k127_496174_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000003934 205.0
PYH1_k127_496174_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000008724 104.0
PYH1_k127_4974147_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 452.0
PYH1_k127_4974147_1 N-acetylmuramoyl-L-alanine amidase K01448 GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 0.00000000000000000003039 93.0
PYH1_k127_4981920_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 295.0
PYH1_k127_5052724_0 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000072 254.0
PYH1_k127_5052724_1 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000002089 141.0
PYH1_k127_5052724_2 Mechanosensitive ion channel K16052 - - 0.00000000000006905 81.0
PYH1_k127_5068000_0 TrkA-C domain - - - 0.000000000000000000000000000000000001385 145.0
PYH1_k127_5068000_1 PhoU domain - - - 0.0000000000000000000000000000102 125.0
PYH1_k127_5068000_2 DinB family - - - 0.0000000003016 65.0
PYH1_k127_5068000_3 DinB superfamily - - - 0.000004675 49.0
PYH1_k127_5122807_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 433.0
PYH1_k127_5122807_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 325.0
PYH1_k127_5122807_2 carboxypeptidase activity K12941,K13048 - - 0.00000000000000000000009151 99.0
PYH1_k127_5176313_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 519.0
PYH1_k127_5204177_0 membrane - - - 0.0000000000000000000000000000006404 135.0
PYH1_k127_5204177_1 Thermophilic metalloprotease (M29) - - - 0.00000001963 66.0
PYH1_k127_5204230_0 PFAM peptidase S58 DmpA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 310.0
PYH1_k127_5204230_1 O-methyltransferase - - - 0.0000000000000000000000000003639 120.0
PYH1_k127_5204230_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000001569 66.0
PYH1_k127_5204770_0 Protein of unknown function (DUF1512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004619 265.0
PYH1_k127_5204770_1 - K01489 - 3.5.4.5 0.00000000004607 67.0
PYH1_k127_526694_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 302.0
PYH1_k127_526694_1 - - - - 0.000000004008 63.0
PYH1_k127_5281406_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K14086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 452.0
PYH1_k127_529067_0 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 349.0
PYH1_k127_529960_0 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 409.0
PYH1_k127_529960_1 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 326.0
PYH1_k127_529960_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 323.0
PYH1_k127_529960_3 GTPase of unknown function C-terminal K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001574 263.0
PYH1_k127_529960_4 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000003922 193.0
PYH1_k127_529960_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000001962 84.0
PYH1_k127_529960_6 Uncharacterized protein conserved in archaea (DUF2095) - - - 0.000000000000007521 79.0
PYH1_k127_529960_7 - - - - 0.00001378 50.0
PYH1_k127_5307575_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 360.0
PYH1_k127_5307575_1 Cytochrome c554 and c-prime - - - 0.000003141 53.0
PYH1_k127_5307777_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1195.0
PYH1_k127_5307777_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000002338 229.0
PYH1_k127_5307777_2 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000001227 137.0
PYH1_k127_5307777_3 Major facilitator superfamily - - - 0.000000000000000000000000000004173 135.0
PYH1_k127_5307777_4 Belongs to the eukaryotic ribosomal protein eL30 family K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002177 108.0
PYH1_k127_530988_0 Peptidase M20 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000139 194.0
PYH1_k127_530988_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000001435 175.0
PYH1_k127_5318060_0 DEAD DEAH box helicase domain protein K03724 - - 0.00000000000000000000000000000000000000000000000001334 193.0
PYH1_k127_5318060_1 Psort location Cytoplasmic, score 8.87 K14591 - - 0.000000000000000000000000000000000000007102 153.0
PYH1_k127_5318060_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.000000000000000000000000000008451 125.0
PYH1_k127_535288_0 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 378.0
PYH1_k127_537505_0 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000007153 168.0
PYH1_k127_537505_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000001434 161.0
PYH1_k127_538596_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 390.0
PYH1_k127_538596_1 Winged helix-turn-helix - - - 0.000000001542 61.0
PYH1_k127_538596_2 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000003386 61.0
PYH1_k127_538596_3 Universal stress protein family - - - 0.000718 48.0
PYH1_k127_5404457_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 519.0
PYH1_k127_5404457_1 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000002726 108.0
PYH1_k127_5404457_2 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000007517 48.0
PYH1_k127_5404457_3 Psort location CytoplasmicMembrane, score 9.99 K06147,K18888 - - 0.00007062 45.0
PYH1_k127_5408068_0 - - - - 0.0000000000000000001348 98.0
PYH1_k127_5408068_1 - - - - 0.0000003988 56.0
PYH1_k127_5409346_0 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001184 258.0
PYH1_k127_5409346_1 - - - - 0.0000000001512 68.0
PYH1_k127_5427921_0 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000005549 189.0
PYH1_k127_5427921_1 Transcriptional regulator K07332 - - 0.000000000000000000002655 101.0
PYH1_k127_5427921_2 Trypsin - - - 0.000000001665 59.0
PYH1_k127_5437579_0 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 410.0
PYH1_k127_5437579_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 411.0
PYH1_k127_5437579_2 Isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 349.0
PYH1_k127_5437579_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000001115 178.0
PYH1_k127_5437579_4 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.00000000000000000000000000000000000000000000002298 175.0
PYH1_k127_5437579_5 lysine biosynthesis protein LysW K05826 - - 0.000000000301 62.0
PYH1_k127_5437579_6 RimK domain protein ATP-grasp K14940 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0043774,GO:0044424,GO:0044464 6.3.2.32 0.00000007942 64.0
PYH1_k127_5453384_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665,K06883 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000000000003048 259.0
PYH1_k127_5453384_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000001264 200.0
PYH1_k127_5453384_2 PFAM HhH-GPD family protein K10773 - 4.2.99.18 0.00000003327 58.0
PYH1_k127_5471324_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 430.0
PYH1_k127_5471324_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000648 282.0
PYH1_k127_548795_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000008041 243.0
PYH1_k127_548795_1 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000005705 161.0
PYH1_k127_548795_2 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000003468 147.0
PYH1_k127_5506532_0 TIGRFAM TIGR04076 family protein - - - 0.0000000000000000000000000000005766 124.0
PYH1_k127_5506532_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000138 119.0
PYH1_k127_5518534_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000002686 230.0
PYH1_k127_5518534_1 zinc finger, SWIM - - - 0.000006897 51.0
PYH1_k127_5518534_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0009594 44.0
PYH1_k127_5540696_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 447.0
PYH1_k127_5540696_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000167 233.0
PYH1_k127_555639_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 454.0
PYH1_k127_5586521_0 Phosphotriesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 350.0
PYH1_k127_5586521_1 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000638 155.0
PYH1_k127_560288_0 - - - - 0.00000000000000000000000000000000000000000000000004585 187.0
PYH1_k127_560288_1 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000003325 136.0
PYH1_k127_560288_2 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000005456 74.0
PYH1_k127_560288_3 PFAM AMP-dependent synthetase and ligase - - - 0.00000001076 67.0
PYH1_k127_560288_4 Putative adhesin - - - 0.00007838 54.0
PYH1_k127_5621098_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000651 262.0
PYH1_k127_5621098_1 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000001977 147.0
PYH1_k127_5621098_2 PFAM Radical SAM - - - 0.000000000000000615 80.0
PYH1_k127_5629947_0 carboxypeptidase activity K12941,K13048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 488.0
PYH1_k127_5629947_1 - - - - 0.00000000000000001207 86.0
PYH1_k127_5629947_2 Membrane protein-like protein - - - 0.000000006506 64.0
PYH1_k127_5646334_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001141 265.0
PYH1_k127_5646334_1 Polysulphide reductase, NrfD - - - 0.0000000000000004028 84.0
PYH1_k127_5661822_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000005227 186.0
PYH1_k127_5661822_1 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000004382 142.0
PYH1_k127_5661822_2 Domain of unknown function (DUF4438) - - - 0.0000000000000000000006507 101.0
PYH1_k127_5709799_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 602.0
PYH1_k127_5709799_1 Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT( ) K00319 - 1.5.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007398 260.0
PYH1_k127_5709799_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000002313 154.0
PYH1_k127_5709799_3 PFAM PUA domain containing protein K07398 - - 0.0000000000000000000000000000000001958 137.0
PYH1_k127_5709799_4 Transcriptional regulator, XRE family K03627 - - 0.0000000000000000001348 94.0
PYH1_k127_5722912_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000886 239.0
PYH1_k127_5745880_0 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 310.0
PYH1_k127_5745880_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 287.0
PYH1_k127_5745880_2 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000003063 238.0
PYH1_k127_5745880_3 Psort location CytoplasmicMembrane, score K12950 - - 0.0000000000000000000000000000000000000000000000000001813 194.0
PYH1_k127_5745880_4 Bacterial PH domain - - - 0.0000000000000000000000000009139 119.0
PYH1_k127_5745880_5 Transcriptional regulator - - - 0.00000000000000000000000982 104.0
PYH1_k127_5745880_6 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000001062 64.0
PYH1_k127_5745880_7 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0002177 51.0
PYH1_k127_5766600_0 PFAM Radical SAM domain protein K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 388.0
PYH1_k127_5766600_1 Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001164 250.0
PYH1_k127_5766600_2 succinyl-diaminopimelate desuccinylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001487 254.0
PYH1_k127_5768101_0 DEAD DEAH box helicase domain protein K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 363.0
PYH1_k127_5768101_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000001968 158.0
PYH1_k127_5768101_2 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000002233 154.0
PYH1_k127_5775075_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.032e-214 682.0
PYH1_k127_5775075_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000005594 227.0
PYH1_k127_5775075_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000007158 200.0
PYH1_k127_5775075_3 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000002093 86.0
PYH1_k127_5782573_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336,K18332 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 495.0
PYH1_k127_5782573_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 380.0
PYH1_k127_5810127_0 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000989 252.0
PYH1_k127_5810127_1 - - - - 0.0000000005207 63.0
PYH1_k127_5810127_2 ThiS family K03636 - - 0.0002586 47.0
PYH1_k127_5834883_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000004494 139.0
PYH1_k127_5836416_0 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000004167 227.0
PYH1_k127_5836416_1 Methionine biosynthesis protein MetW - - - 0.0000000001766 65.0
PYH1_k127_5836416_2 Domain of unknown function (DUF4143) K07133 - - 0.0002229 48.0
PYH1_k127_5849239_0 Belongs to the peptidase M24B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 301.0
PYH1_k127_5849239_1 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000007288 122.0
PYH1_k127_5849239_2 PFAM glutaredoxin - - - 0.000000000000000000007153 94.0
PYH1_k127_5850469_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 481.0
PYH1_k127_5850469_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 455.0
PYH1_k127_5850469_2 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
PYH1_k127_5850469_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000006431 191.0
PYH1_k127_5876987_0 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000009883 203.0
PYH1_k127_5876987_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000004372 141.0
PYH1_k127_5879052_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005906 226.0
PYH1_k127_5879052_1 transporter K07238 - - 0.00000000000000000000000000000000000000000000988 171.0
PYH1_k127_5879052_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000005685 135.0
PYH1_k127_5881506_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000001081 183.0
PYH1_k127_5881506_1 QDE-2-interacting protein - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000005251 88.0
PYH1_k127_5897647_0 heavy metal-(Cd Co Hg Pb Zn)-translocating K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 467.0
PYH1_k127_5897647_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000006286 181.0
PYH1_k127_5897647_2 - - - - 0.0000000000004374 74.0
PYH1_k127_5949205_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 340.0
PYH1_k127_5949205_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000002879 98.0
PYH1_k127_5953596_0 - - - - 0.000000000000000000000000000000000000000000000000000004735 197.0
PYH1_k127_5953596_1 excinuclease ABC, C subunit - - - 0.000000000000000000000000003218 114.0
PYH1_k127_5957030_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 460.0
PYH1_k127_5981147_0 glycerol ether metabolic process K03671 - - 0.00000000000000000000000001074 114.0
PYH1_k127_5981147_1 HD domain - - - 0.000000000864 64.0
PYH1_k127_6010953_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000001216 218.0
PYH1_k127_6010953_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000001566 169.0
PYH1_k127_6039884_0 COG0145 N-methylhydantoinase A acetone carboxylase beta subunit K01469,K01473 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0017168,GO:0034641,GO:0043603,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071704,GO:1901564 3.5.2.14,3.5.2.9 1.815e-196 633.0
PYH1_k127_6039884_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.000000000000000000000000000000000000000000000000000000001466 207.0
PYH1_k127_6039884_2 NUDIX domain - - - 0.000000000000000000000000000000000002414 142.0
PYH1_k127_6039884_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000001443 115.0
PYH1_k127_606132_0 Putative peptidoglycan binding domain - - - 0.00002177 57.0
PYH1_k127_6062519_0 DNA restriction-modification system - - - 0.0000000000000000000000000000000000000000000006451 172.0
PYH1_k127_6062968_0 Cys/Met metabolism PLP-dependent enzyme K01556,K01620 - 3.7.1.3,4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 323.0
PYH1_k127_6062968_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001348 252.0
PYH1_k127_6062968_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000003106 154.0
PYH1_k127_6062968_3 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000003812 51.0
PYH1_k127_608414_0 Class II Aldolase and Adducin N-terminal domain K01628,K03077 - 4.1.2.17,5.1.3.4 0.000000000000000000000000000000001377 138.0
PYH1_k127_608414_1 PFAM coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00441 - 1.12.98.1 0.00000000000000000002752 92.0
PYH1_k127_608414_2 hydroxypyruvate reductase K11529 - 2.7.1.165 0.000000000000000007451 85.0
PYH1_k127_608414_3 Belongs to the UPF0292 family - - - 0.00000001224 61.0
PYH1_k127_6102502_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 601.0
PYH1_k127_6102502_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 375.0
PYH1_k127_6102502_2 Pantothenate synthetase K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 299.0
PYH1_k127_6102502_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000003218 244.0
PYH1_k127_6102502_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000005043 187.0
PYH1_k127_6102502_5 acetolactate synthase, small K01653 - 2.2.1.6 0.000000000000000000000000000000000000003694 152.0
PYH1_k127_6120634_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 482.0
PYH1_k127_6120634_1 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000276 150.0
PYH1_k127_6149983_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000005643 138.0
PYH1_k127_6149983_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000001381 57.0
PYH1_k127_6149983_2 Sec61beta family - - - 0.000008338 49.0
PYH1_k127_6149983_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0004845 45.0
PYH1_k127_6174638_0 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000002103 176.0
PYH1_k127_6174638_1 Zinc carboxypeptidase K14054 - - 0.0000000000000000000001398 100.0
PYH1_k127_6174638_2 TIGRFAM TIGR04076 family protein - - - 0.0000000000000000004316 90.0
PYH1_k127_6174638_3 aminopeptidase activity K07004 - - 0.000000000000000001759 93.0
PYH1_k127_6174638_4 Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000001088 72.0
PYH1_k127_6174638_5 - - - - 0.00002729 53.0
PYH1_k127_6200620_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 9.928e-230 724.0
PYH1_k127_6205843_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000002117 198.0
PYH1_k127_6205843_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000005361 130.0
PYH1_k127_6205843_2 - - - - 0.00000005178 57.0
PYH1_k127_6222252_0 Protein of unknown function (DUF917) K09703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002644 262.0
PYH1_k127_6222252_1 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.00000000000000000000000000000000000006882 153.0
PYH1_k127_6222252_2 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000006792 97.0
PYH1_k127_6241014_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 438.0
PYH1_k127_6241014_1 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000008913 210.0
PYH1_k127_6241014_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000001389 205.0
PYH1_k127_6241014_3 PFAM phosphoesterase, PA-phosphatase related K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.0000000008459 68.0
PYH1_k127_6245964_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000007918 166.0
PYH1_k127_6245964_1 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000002712 81.0
PYH1_k127_6245964_2 Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination K04482 GO:0000003,GO:0000150,GO:0000217,GO:0000228,GO:0000280,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0000793,GO:0000794,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007127,GO:0007131,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009889,GO:0009987,GO:0010212,GO:0010332,GO:0010468,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0022607,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0033554,GO:0034622,GO:0034641,GO:0035825,GO:0042148,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045003,GO:0046483,GO:0048285,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051321,GO:0051716,GO:0060255,GO:0061982,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070192,GO:0071704,GO:0071824,GO:0071840,GO:0080090,GO:0090304,GO:0090735,GO:0097159,GO:0140013,GO:0140097,GO:1901360,GO:1901363,GO:1903046,GO:1903506,GO:2000112,GO:2001141 - 0.0002798 43.0
PYH1_k127_6252462_0 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000007487 182.0
PYH1_k127_6264274_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 433.0
PYH1_k127_6264274_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 - 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 385.0
PYH1_k127_6264274_2 Thioesterase superfamily - - - 0.00000000000000000000000000292 115.0
PYH1_k127_6264274_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014 - - 0.0000000000000000002196 91.0
PYH1_k127_6266328_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000006627 206.0
PYH1_k127_6266328_1 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000003229 211.0
PYH1_k127_6266328_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000001525 102.0
PYH1_k127_6266328_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000006496 89.0
PYH1_k127_6266328_4 endoribonuclease L-PSP - - - 0.0000000000006306 71.0
PYH1_k127_6284175_0 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 298.0
PYH1_k127_6284175_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025,K08723 - 3.1.3.5 0.00000000000005006 80.0
PYH1_k127_6284175_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000001839 74.0
PYH1_k127_6304034_0 Oligopeptidase F K08602 - - 1.438e-224 711.0
PYH1_k127_6304034_1 Major facilitator Superfamily K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 322.0
PYH1_k127_6304034_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001665 244.0
PYH1_k127_6304034_3 Pyridoxamine 5-phosphate K07005 - - 0.0000000000000000000000000196 114.0
PYH1_k127_6304034_4 CBS domain - - - 0.0000000000000000001971 93.0
PYH1_k127_6304034_5 Parallel beta-helix repeats - - - 0.00000000001654 75.0
PYH1_k127_6308167_0 Zinc carboxypeptidase K14054 - - 7.402e-211 677.0
PYH1_k127_6319657_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 429.0
PYH1_k127_6319657_1 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 327.0
PYH1_k127_6319657_2 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
PYH1_k127_6320255_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 333.0
PYH1_k127_6320255_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000004624 248.0
PYH1_k127_6320255_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000001446 163.0
PYH1_k127_6320255_3 - - - - 0.00000000000000000000000000000002607 135.0
PYH1_k127_633899_0 aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 457.0
PYH1_k127_633899_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - 0.00000000000000000000000000000000000000000000000000000000000000000005128 234.0
PYH1_k127_633899_2 ACT domain protein - - - 0.00000000000148 73.0
PYH1_k127_6357555_0 ABC-type uncharacterized transport system - - - 0.00000000008036 68.0
PYH1_k127_6380433_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000004368 126.0
PYH1_k127_6380433_1 Transcriptional regulator K07729 - - 0.0000000000000002121 80.0
PYH1_k127_6401133_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 466.0
PYH1_k127_6401133_1 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000001876 226.0
PYH1_k127_6402558_0 LOR SDH bifunctional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 460.0
PYH1_k127_6402558_1 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000001897 216.0
PYH1_k127_6402558_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000001069 164.0
PYH1_k127_6403048_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 460.0
PYH1_k127_6403048_1 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000696 273.0
PYH1_k127_6403048_2 nitric oxide reductase activity - - - 0.0000000000000000000000002418 111.0
PYH1_k127_6403048_3 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0002778 52.0
PYH1_k127_6403751_0 PAC2 family K07159 - - 0.00000000000000000000007034 108.0
PYH1_k127_6403751_1 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000002875 86.0
PYH1_k127_6431950_0 Putative esterase K07017 - - 0.00000000000000000000000008083 112.0
PYH1_k127_6431950_1 M6 family metalloprotease domain protein - - - 0.0001107 55.0
PYH1_k127_6437784_0 PFAM D-aminoacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000004612 263.0
PYH1_k127_6437784_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000222 192.0
PYH1_k127_6437784_2 COG1921 Selenocysteine synthase seryl-tRNASer selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000002686 190.0
PYH1_k127_6437784_3 - K07092 - - 0.0000000000000000000000000000000000000000000002156 169.0
PYH1_k127_6437784_4 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000006665 143.0
PYH1_k127_6442911_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
PYH1_k127_6442911_1 PFAM phosphatidate cytidylyltransferase - - - 0.0000000000000000000000000000000000000000002334 167.0
PYH1_k127_6442911_2 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000007043 149.0
PYH1_k127_6442911_3 Amidase - - - 0.00000000000001832 76.0
PYH1_k127_644486_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 301.0
PYH1_k127_644486_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000002418 235.0
PYH1_k127_644486_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000009643 120.0
PYH1_k127_6457240_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000001067 175.0
PYH1_k127_6469305_0 transcription regulator activity K03718 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000002571 108.0
PYH1_k127_6469305_1 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.000000000000000000003896 101.0
PYH1_k127_6469305_2 Sulfite exporter TauE/SafE K07090 - - 0.0000002443 58.0
PYH1_k127_6472265_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 519.0
PYH1_k127_6472265_1 COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN K01492 - 2.1.2.2,2.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001341 263.0
PYH1_k127_6472265_2 IMP cyclohydrolase activity K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000002442 200.0
PYH1_k127_6472265_3 peptidase K01303 - 3.4.19.1 0.0000000000000000000000003482 112.0
PYH1_k127_6472265_4 Arginine deiminase K01478 - 3.5.3.6 0.0000000000000000001615 102.0
PYH1_k127_6472265_5 Protein of unknown function (DUF3795) - - - 0.00000000000001036 78.0
PYH1_k127_6472265_6 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.00002397 49.0
PYH1_k127_6489673_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000002556 129.0
PYH1_k127_6494786_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 391.0
PYH1_k127_6494786_1 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002334 286.0
PYH1_k127_6494786_2 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.000000003767 59.0
PYH1_k127_6509562_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 436.0
PYH1_k127_6509562_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 371.0
PYH1_k127_6509562_2 PFAM molybdopterin binding domain K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000008563 196.0
PYH1_k127_6520467_0 COG0568 DNA-directed RNA polymerase, sigma subunit K03087 GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000196 98.0
PYH1_k127_6521297_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 410.0
PYH1_k127_6521297_1 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000003969 162.0
PYH1_k127_6521297_2 - - - - 0.00000000009722 66.0
PYH1_k127_654368_0 COG0852 NADH ubiquinone oxidoreductase 27 kD subunit K00333,K13378,K22172,K22173 - 1.1.98.4,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 302.0
PYH1_k127_654368_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000002658 163.0
PYH1_k127_654368_2 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000003317 146.0
PYH1_k127_654368_3 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K00332 - 1.6.5.3 0.0000000000000000000005946 101.0
PYH1_k127_654368_4 helix_turn_helix ASNC type - - - 0.000000000000002134 87.0
PYH1_k127_654368_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0007114 47.0
PYH1_k127_6548320_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009519 264.0
PYH1_k127_6548320_1 Fibrobacter succinogenes major domain (Fib_succ_major) - - - 0.00000000000000000000000000000000000000000087 164.0
PYH1_k127_6548320_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000002078 137.0
PYH1_k127_6548320_3 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000001358 145.0
PYH1_k127_6573732_0 Aminotransferase K00812,K10907,K14155 - 2.6.1.1,4.4.1.8 0.00000000000000000000000000000000000000000000001337 181.0
PYH1_k127_6573732_1 UbiA prenyltransferase family K20616 - - 0.000000000000000000000000000000001299 137.0
PYH1_k127_6585585_0 Heat shock 70 kDa protein K04043 - - 7.693e-231 730.0
PYH1_k127_6585585_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000002261 178.0
PYH1_k127_6585585_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000009737 100.0
PYH1_k127_6602446_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001939 232.0
PYH1_k127_6602446_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000009317 231.0
PYH1_k127_6602446_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000008549 114.0
PYH1_k127_6602446_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00000000004804 68.0
PYH1_k127_6602446_4 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.0007178 45.0
PYH1_k127_6606830_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates - GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0030880,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:1902494,GO:1990234 - 0.0 1003.0
PYH1_k127_6624289_0 Amidinotransferase - - - 0.00000000000000000000008307 109.0
PYH1_k127_6624289_1 Belongs to the peptidase M24B family - - - 0.0000000000001938 73.0
PYH1_k127_6651869_0 Zinc carboxypeptidase K14054 - - 0.0 1023.0
PYH1_k127_6707046_0 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 410.0
PYH1_k127_6707046_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 318.0
PYH1_k127_6707046_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000001013 56.0
PYH1_k127_6707046_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000001232 58.0
PYH1_k127_6719909_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 384.0
PYH1_k127_6719909_1 - K02339 - 2.7.7.7 0.00000000000000000001524 99.0
PYH1_k127_6719909_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000001237 80.0
PYH1_k127_6732108_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000005975 187.0
PYH1_k127_6732108_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000002416 121.0
PYH1_k127_6732108_2 Transcriptional regulator IclR K13641 - - 0.0000000000000000000001198 101.0
PYH1_k127_6737499_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 430.0
PYH1_k127_6737499_1 Belongs to the complex I 20 kDa subunit family K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000385 138.0
PYH1_k127_6737499_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000001524 85.0
PYH1_k127_677554_0 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000002104 202.0
PYH1_k127_677554_1 PFAM ParB domain protein nuclease - - - 0.000000000000000000000000000000000000000000000000006906 191.0
PYH1_k127_677554_2 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000007192 132.0
PYH1_k127_677554_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000001246 83.0
PYH1_k127_677554_4 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.0000000000000145 75.0
PYH1_k127_677554_5 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000003049 72.0
PYH1_k127_677554_6 Cytidylyltransferase-like K00952 - 2.7.7.1 0.000000000008746 65.0
PYH1_k127_6795739_0 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 379.0
PYH1_k127_6795739_1 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000001309 196.0
PYH1_k127_6795739_2 - - - - 0.000000000000000000000000000008137 125.0
PYH1_k127_6798356_0 ABC-type transport system involved in cytochrome c biogenesis permease component K02195 - - 0.00000000000000000000000000000000000000000000009322 176.0
PYH1_k127_6798356_1 PFAM Cytochrome c assembly protein K02198 - - 0.00000000000000001761 89.0
PYH1_k127_6798356_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000002904 67.0
PYH1_k127_6798356_3 PFAM ABC transporter K01990 - - 0.00000001488 56.0
PYH1_k127_6830454_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000001564 152.0
PYH1_k127_6907586_0 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000003273 265.0
PYH1_k127_6907586_1 - - - - 0.0000000000000000000000000001605 119.0
PYH1_k127_6907586_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000006098 102.0
PYH1_k127_6910464_0 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 312.0
PYH1_k127_6910464_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000001656 131.0
PYH1_k127_6910464_2 Diphthamide synthase K06927 - 6.3.1.14 0.00000000001712 65.0
PYH1_k127_6910464_3 - - - - 0.0000000001983 63.0
PYH1_k127_6910464_4 DUF72 domain containing protein - - - 0.00003359 47.0
PYH1_k127_6942279_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 426.0
PYH1_k127_6942279_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 432.0
PYH1_k127_6942279_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 308.0
PYH1_k127_6942279_3 COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
PYH1_k127_6942279_4 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000019 248.0
PYH1_k127_6942279_5 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000009122 216.0
PYH1_k127_6942279_6 SMART KH domain protein K06961 - - 0.00000000000000000000000000000000000000000004965 168.0
PYH1_k127_6942279_7 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000008199 108.0
PYH1_k127_6942279_8 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000006835 94.0
PYH1_k127_6957464_0 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 401.0
PYH1_k127_6957464_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 320.0
PYH1_k127_6957464_2 - - - - 0.000000000000000000000000000000000000001053 151.0
PYH1_k127_6957464_3 GrpB protein - - - 0.0005693 43.0
PYH1_k127_7023587_0 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000001243 209.0
PYH1_k127_7023587_1 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000007611 119.0
PYH1_k127_7023587_2 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000001956 74.0
PYH1_k127_7023587_3 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.000000001637 60.0
PYH1_k127_7023587_4 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.000000008316 59.0
PYH1_k127_7023587_5 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000001116 60.0
PYH1_k127_7025041_0 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000005386 145.0
PYH1_k127_7034302_0 Beta-Casp domain K07041 - - 5.197e-202 647.0
PYH1_k127_7034302_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000004608 196.0
PYH1_k127_7034302_2 Pfam:DUF552 K09152 - - 0.000006093 48.0
PYH1_k127_7042984_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 440.0
PYH1_k127_7042984_1 Rubrerythrin - - - 0.000000000000000001054 86.0
PYH1_k127_7042984_2 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.00000007365 56.0
PYH1_k127_7073852_0 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000002558 223.0
PYH1_k127_7073852_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000005521 176.0
PYH1_k127_7073852_2 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000000001576 147.0
PYH1_k127_7138863_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 390.0
PYH1_k127_7138863_1 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.0000000000000000000000000000000000000000000000001738 183.0
PYH1_k127_7138863_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000009972 85.0
PYH1_k127_7141389_0 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 516.0
PYH1_k127_7155547_0 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000006443 134.0
PYH1_k127_7155547_1 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000005159 96.0
PYH1_k127_7155547_2 Inositol monophosphatase family K01092 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000002124 77.0
PYH1_k127_7188846_0 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 278.0
PYH1_k127_7229709_0 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000007378 178.0
PYH1_k127_7229709_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000000003337 141.0
PYH1_k127_7229709_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000003437 141.0
PYH1_k127_7229709_3 4Fe-4S single cluster domain - - - 0.00000000000000001933 83.0
PYH1_k127_7255217_0 - - - - 0.000000000000000000666 87.0
PYH1_k127_7255217_1 - - - - 0.0001358 49.0
PYH1_k127_7280179_0 Baseplate assembly protein - - - 0.00000000000002158 83.0
PYH1_k127_7294205_0 NADH dehydrogenase K00337,K14087 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004632 254.0
PYH1_k127_7294205_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002295 246.0
PYH1_k127_7294205_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000002587 178.0
PYH1_k127_7299763_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 367.0
PYH1_k127_7299763_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 342.0
PYH1_k127_7342302_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 569.0
PYH1_k127_7342302_1 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 436.0
PYH1_k127_7342302_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 336.0
PYH1_k127_7342302_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 299.0
PYH1_k127_7342302_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000006778 227.0
PYH1_k127_7342302_5 NUDIX domain - - - 0.0000000000000000000001456 104.0
PYH1_k127_7342302_6 Belongs to the thioredoxin family K03671 - - 0.000000001512 66.0
PYH1_k127_7352242_0 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 313.0
PYH1_k127_7352242_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003083 262.0
PYH1_k127_7352242_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000003376 198.0
PYH1_k127_7352242_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000009081 152.0
PYH1_k127_7352242_4 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000001924 138.0
PYH1_k127_7352242_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000002895 119.0
PYH1_k127_7352242_6 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000006819 96.0
PYH1_k127_7352242_7 Belongs to the universal stress protein A family - - - 0.00000000000000004342 87.0
PYH1_k127_737281_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
PYH1_k127_737281_1 - - - - 0.00000003243 59.0
PYH1_k127_7382966_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000004605 137.0
PYH1_k127_7382966_1 - - - - 0.000000061 58.0
PYH1_k127_7382966_2 Protein of unknown function (DUF3795) - - - 0.000001851 52.0
PYH1_k127_7387014_0 Large family of predicted nucleotide-binding domains - - - 0.000005895 55.0
PYH1_k127_7387014_1 SpoVT / AbrB like domain - - - 0.000007034 51.0
PYH1_k127_7400333_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 2.388e-210 670.0
PYH1_k127_7400333_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000001083 196.0
PYH1_k127_7400333_2 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000006655 110.0
PYH1_k127_7400333_3 Molybdopterin converting factor, small subunit K03636 - - 0.00002144 51.0
PYH1_k127_7465918_0 Amidohydrolase family K01465,K01466 - 3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 324.0
PYH1_k127_7465918_1 PFAM D-aminoacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000004719 244.0
PYH1_k127_7465918_2 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000002635 109.0
PYH1_k127_7465918_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000003793 111.0
PYH1_k127_7465918_4 Major Facilitator Superfamily - - - 0.000007243 55.0
PYH1_k127_7514048_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000002493 225.0
PYH1_k127_7514048_1 Creatinase/Prolidase N-terminal domain - - - 0.000003514 54.0
PYH1_k127_7514048_2 the major facilitator superfamily - - - 0.00007605 53.0
PYH1_k127_7541871_0 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000581 270.0
PYH1_k127_7541871_1 TIGRFAM geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000002571 117.0
PYH1_k127_7546754_0 PFAM metallophosphoesterase - - - 0.00000000000000000000000003422 126.0
PYH1_k127_7550799_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 361.0
PYH1_k127_7550799_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001279 253.0
PYH1_k127_7550799_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.00000000000000000000000000000000000000000000000000000000014 214.0
PYH1_k127_7569563_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 418.0
PYH1_k127_7569563_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000002094 249.0
PYH1_k127_7569563_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000002145 215.0
PYH1_k127_7569563_3 PFAM Transcription elongation factor Elf1 like - - - 0.000004884 52.0
PYH1_k127_7579761_0 peptidase K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 360.0
PYH1_k127_7614502_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000005509 121.0
PYH1_k127_7614502_1 PFAM ABC transporter related K02003 - - 0.000001771 49.0
PYH1_k127_76565_0 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.0000000000000000000000000000001403 137.0
PYH1_k127_76565_1 Serine aminopeptidase, S33 - - - 0.0000000000003048 77.0
PYH1_k127_7657639_0 - - - - 0.0000000000001996 74.0
PYH1_k127_7657639_1 DNA polymerase III, epsilon K02342 - 2.7.7.7 0.00003245 53.0
PYH1_k127_767978_0 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 371.0
PYH1_k127_767978_1 Helix-turn-helix domain K07731 - - 0.000000000000000000000000000000000000000000000000000000000000001549 224.0
PYH1_k127_767978_2 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000007763 220.0
PYH1_k127_7789686_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1212.0
PYH1_k127_7789686_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 521.0
PYH1_k127_7789686_2 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 308.0
PYH1_k127_7800364_0 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000007975 218.0
PYH1_k127_7800364_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000002584 128.0
PYH1_k127_7800364_2 succinyl-diaminopimelate desuccinylase activity K01439 - 3.5.1.18 0.000000000000000000000002178 109.0
PYH1_k127_7847777_0 small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 471.0
PYH1_k127_7847777_1 PFAM Pyridoxamine 5'-phosphate oxidase-related K07005 - - 0.000000000000000000000001036 109.0
PYH1_k127_7847777_2 OsmC-like protein - - - 0.00000000002542 65.0
PYH1_k127_7851608_0 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 550.0
PYH1_k127_7851608_1 aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 296.0
PYH1_k127_7851608_2 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000001702 222.0
PYH1_k127_7851608_3 membrane - - - 0.000000000000000001005 89.0
PYH1_k127_7856642_0 PFAM extracellular solute-binding protein family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 390.0
PYH1_k127_7856642_1 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000000000000005984 120.0
PYH1_k127_7865807_0 aconitate hydratase K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 563.0
PYH1_k127_7865807_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 379.0
PYH1_k127_7867385_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 409.0
PYH1_k127_7867385_1 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00003064 52.0
PYH1_k127_7885942_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000003811 139.0
PYH1_k127_7885942_1 Major Facilitator Superfamily - - - 0.0000000000004321 79.0
PYH1_k127_788787_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 531.0
PYH1_k127_788787_1 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.00000000000000000000000000000001618 134.0
PYH1_k127_788787_2 - - - - 0.000000000000000000000000073 111.0
PYH1_k127_788787_3 ribosomal protein K02976 - - 0.0000000000000000000000007042 107.0
PYH1_k127_788787_4 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000001755 93.0
PYH1_k127_788787_5 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000006771 77.0
PYH1_k127_788787_6 GDSL-like Lipase/Acylhydrolase - - - 0.000000000003654 74.0
PYH1_k127_79061_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001476 261.0
PYH1_k127_79061_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000001626 89.0
PYH1_k127_79061_2 - - - - 0.00000000000131 75.0
PYH1_k127_79061_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00001383 49.0
PYH1_k127_7929223_0 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 306.0
PYH1_k127_7929223_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000001357 207.0
PYH1_k127_7929223_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000009165 122.0
PYH1_k127_7929696_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 441.0
PYH1_k127_7929696_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000003442 63.0
PYH1_k127_7929696_2 Nucleoredoxin K17609 GO:0000003,GO:0000902,GO:0000904,GO:0001558,GO:0003006,GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009636,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0010183,GO:0010769,GO:0015036,GO:0016043,GO:0016049,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0022414,GO:0022603,GO:0022604,GO:0030154,GO:0032501,GO:0032502,GO:0032989,GO:0040007,GO:0040008,GO:0040011,GO:0042221,GO:0042330,GO:0043900,GO:0044424,GO:0044444,GO:0044464,GO:0044706,GO:0045595,GO:0046686,GO:0048468,GO:0048588,GO:0048589,GO:0048638,GO:0048856,GO:0048868,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0050918,GO:0051128,GO:0051239,GO:0051510,GO:0051704,GO:0051716,GO:0055114,GO:0060284,GO:0060560,GO:0065007,GO:0070887,GO:0071840,GO:0080092,GO:0097237,GO:0098754,GO:0098869,GO:1990748,GO:2000241 1.8.1.8 0.00002197 50.0
PYH1_k127_7954181_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003182 274.0
PYH1_k127_7954181_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001947 263.0
PYH1_k127_7954181_2 50S ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009875 250.0
PYH1_k127_7954181_3 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000007706 157.0
PYH1_k127_7954181_4 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001437 105.0
PYH1_k127_7959097_0 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 293.0
PYH1_k127_7959097_1 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000007354 239.0
PYH1_k127_7959097_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000003847 158.0
PYH1_k127_7959097_3 signal transduction protein with CBS domains - - - 0.0000000000000000000000005258 109.0
PYH1_k127_7974331_0 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 462.0
PYH1_k127_7974331_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000007883 201.0
PYH1_k127_797728_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.448e-286 895.0
PYH1_k127_797728_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000001302 133.0
PYH1_k127_7982251_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - 0.0000000000000000000000000000000000000000003379 175.0
PYH1_k127_7982251_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000002393 78.0
PYH1_k127_8004122_0 4-phosphoerythronate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005666 248.0
PYH1_k127_8004122_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000001257 190.0
PYH1_k127_8004122_2 - - - - 0.000000000000000000000000000000000000000009097 159.0
PYH1_k127_8004122_3 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000412 153.0
PYH1_k127_8018236_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000001772 197.0
PYH1_k127_8018236_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000003169 69.0
PYH1_k127_8043572_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000005191 165.0
PYH1_k127_8043572_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000003139 96.0
PYH1_k127_8043572_2 TIGRFAM C_GCAxxG_C_C family - - - 0.0000000000000785 78.0
PYH1_k127_8043572_3 Uncharacterised ArCR, COG2043 - - - 0.00000001038 62.0
PYH1_k127_8053859_0 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000001095 211.0
PYH1_k127_8053859_1 Aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000001137 203.0
PYH1_k127_8053859_2 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) K01955 - 6.3.5.5 0.00000000000004335 72.0
PYH1_k127_8114470_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 310.0
PYH1_k127_8114470_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000002709 198.0
PYH1_k127_8114470_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000001899 195.0
PYH1_k127_8114470_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003962 175.0
PYH1_k127_8114470_4 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000306 153.0
PYH1_k127_8124022_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001268 274.0
PYH1_k127_8124022_1 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000101 182.0
PYH1_k127_8124022_2 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000001519 162.0
PYH1_k127_8124022_3 transglutaminase domain protein - - - 0.00000000000000000000002063 113.0
PYH1_k127_8131417_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 319.0
PYH1_k127_8131417_1 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000009337 248.0
PYH1_k127_8131417_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000004026 211.0
PYH1_k127_8131417_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000002111 175.0
PYH1_k127_8131417_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000004534 173.0
PYH1_k127_8131417_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000002252 147.0
PYH1_k127_8131417_6 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000003924 104.0
PYH1_k127_8131417_7 HupF/HypC family K04653 - - 0.00000000000000003311 83.0
PYH1_k127_8145517_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 299.0
PYH1_k127_8145517_1 Putative esterase K07017 - - 0.0000000000000000000000000000005988 132.0
PYH1_k127_8150725_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 376.0
PYH1_k127_8158599_0 Glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 359.0
PYH1_k127_8158599_1 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0007961 44.0
PYH1_k127_8168659_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 378.0
PYH1_k127_8168659_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 357.0
PYH1_k127_8168659_2 tRNA synthetases class II (A) K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000005824 220.0
PYH1_k127_8168659_3 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000001178 191.0
PYH1_k127_8168659_4 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000006424 184.0
PYH1_k127_8168659_5 TIGRFAM histidinol phosphate phosphatase HisJ K04486 - 3.1.3.15 0.0000000000000000000000000000000000005271 150.0
PYH1_k127_8168659_6 QueT transporter - - - 0.00000000003584 70.0
PYH1_k127_8168659_7 Protein of unknown function (DUF998) - - - 0.0000000002363 68.0
PYH1_k127_8223505_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000007911 141.0
PYH1_k127_8223505_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000654 62.0
PYH1_k127_8228394_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 2.795e-213 682.0
PYH1_k127_8228394_1 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00018 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.26,1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 417.0
PYH1_k127_8228394_2 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000005759 174.0
PYH1_k127_8228394_3 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000006208 170.0
PYH1_k127_8228394_4 - - - - 0.00000000000000000000000000000000001326 144.0
PYH1_k127_8228394_5 - - - - 0.00000000000000000000000005357 115.0
PYH1_k127_8248527_0 PFAM NADH-ubiquinone oxidoreductase chain 49kDa K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 327.0
PYH1_k127_8248527_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000009668 244.0
PYH1_k127_8250199_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 381.0
PYH1_k127_8250199_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000002091 223.0
PYH1_k127_8266134_0 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 467.0
PYH1_k127_8266134_1 COGs COG3842 ABC-type spermidine putrescine transport systems ATPase components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 338.0
PYH1_k127_8267255_0 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000001874 192.0
PYH1_k127_8267255_1 TIGRFAM Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000000000001998 193.0
PYH1_k127_8279319_0 PFAM ABC transporter related K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 469.0
PYH1_k127_8279319_1 DHH family - - - 0.000000000006395 70.0
PYH1_k127_8285819_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000001042 58.0
PYH1_k127_8285819_1 - - - - 0.000007003 58.0
PYH1_k127_8298659_0 ATPases associated with a variety of cellular activities K10112,K17240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 294.0
PYH1_k127_8298659_1 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000005162 235.0
PYH1_k127_8298659_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000001055 185.0
PYH1_k127_8298659_3 PFAM Putitive phosphate transport regulator K07220 - - 0.000000000000002344 84.0
PYH1_k127_8305165_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 355.0
PYH1_k127_8305165_1 (Rhomboid) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002271 282.0
PYH1_k127_830748_0 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 321.0
PYH1_k127_830748_1 TIGRFAM reductive dehalogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001587 248.0
PYH1_k127_830748_2 Amidohydrolase family - - - 0.0000000007819 62.0
PYH1_k127_8308115_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000157 285.0
PYH1_k127_8308115_1 PFAM Metallophosphoesterase K03547 - - 0.0000000000000001943 91.0
PYH1_k127_8339721_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000731 243.0
PYH1_k127_8339721_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000469 233.0
PYH1_k127_8345652_0 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.00000000000000000000000000000000000000000000000000105 196.0
PYH1_k127_8345652_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000007611 119.0
PYH1_k127_8345886_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003828 242.0
PYH1_k127_8345886_1 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000009441 207.0
PYH1_k127_8345886_2 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000001997 143.0
PYH1_k127_8345886_3 dihydrofolate synthase activity K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000001231 59.0
PYH1_k127_8347432_0 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 556.0
PYH1_k127_8347432_1 transport protein CorA - - - 0.00000000000000000000000000000000000000000000001513 173.0
PYH1_k127_8350922_0 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 2.521e-250 789.0
PYH1_k127_8350922_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000002394 230.0
PYH1_k127_8350922_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000002767 211.0
PYH1_k127_8350922_3 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000003045 59.0
PYH1_k127_8357389_0 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 293.0
PYH1_k127_8357389_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000914 280.0
PYH1_k127_8358730_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000001269 188.0
PYH1_k127_8358730_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000004886 142.0
PYH1_k127_8362776_0 PFAM Na Picotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 422.0
PYH1_k127_8362776_1 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.00000000000000000000001789 101.0
PYH1_k127_8365162_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 357.0
PYH1_k127_8365162_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005539 278.0
PYH1_k127_8365162_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000001556 226.0
PYH1_k127_8365162_3 phosphatase activity K07025,K08723,K20862 - 3.1.3.102,3.1.3.104,3.1.3.5 0.0000000000000000000000000000323 127.0
PYH1_k127_8368227_0 PFAM Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000008798 131.0
PYH1_k127_8368227_1 Thioredoxin - - - 0.0000000000000000000000000002931 122.0
PYH1_k127_8368227_3 Neuroblast differentiation-associated protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0098827 - 0.0007853 51.0
PYH1_k127_8368415_0 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000007669 231.0
PYH1_k127_8368415_1 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000005688 203.0
PYH1_k127_8368415_2 Psort location Cytoplasmic, score - - - 0.0000003583 51.0
PYH1_k127_8368415_3 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.000002746 49.0
PYH1_k127_85229_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000879 45.0
PYH1_k127_861112_0 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000004376 110.0
PYH1_k127_861628_0 Psort location Cytoplasmic, score K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 563.0
PYH1_k127_861628_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000001313 179.0
PYH1_k127_861628_2 PFAM regulatory protein AsnC Lrp family - - - 0.000001234 53.0
PYH1_k127_861628_3 PFAM regulatory protein AsnC Lrp family - - - 0.000002617 53.0
PYH1_k127_902833_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 8.072e-229 740.0
PYH1_k127_902833_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 560.0
PYH1_k127_902833_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000009615 153.0
PYH1_k127_908117_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000001764 177.0
PYH1_k127_908117_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000309 169.0
PYH1_k127_908117_2 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000000001962 119.0
PYH1_k127_928948_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001132 291.0
PYH1_k127_929204_0 RmlD substrate binding domain K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 402.0
PYH1_k127_929204_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01620 - 2.3.1.29,2.3.1.47,4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 405.0
PYH1_k127_929204_2 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000008849 89.0
PYH1_k127_93634_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000006727 220.0
PYH1_k127_93634_1 - - - - 0.00000002671 64.0
PYH1_k127_982570_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 548.0
PYH1_k127_982570_1 PFAM Methyl-viologen-reducing hydrogenase, delta subunit K22480 - 1.8.7.3 0.000000000000000000000000000001679 129.0