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Overview

ID MAG03166
Name PYH1_bin.65
Sample SMP0073
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-39
Genus 2-02-FULL-66-14
Species
Assembly information
Completeness (%) 96.15
Contamination (%) 2.86
GC content (%) 68.0
N50 (bp) 11,908
Genome size (bp) 3,221,550

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3360

Gene name Description KEGG GOs EC E-value Score Sequence
PYH1_k127_1006933_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 529.0
PYH1_k127_1006933_1 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000001462 175.0
PYH1_k127_1039483_0 Diguanylate cyclase - - - 4.685e-295 936.0
PYH1_k127_1039483_1 elongation factor G K02355 - - 7.14e-294 915.0
PYH1_k127_1039483_10 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 331.0
PYH1_k127_1039483_11 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 339.0
PYH1_k127_1039483_12 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 297.0
PYH1_k127_1039483_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000135 271.0
PYH1_k127_1039483_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 268.0
PYH1_k127_1039483_15 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000197 184.0
PYH1_k127_1039483_16 gluconolactonase activity K01053,K02352 - 3.1.1.17 0.000000000000000000000000000000000000000000001169 177.0
PYH1_k127_1039483_17 - - - - 0.000000000000000000000000000000000000000000004192 171.0
PYH1_k127_1039483_19 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000001594 130.0
PYH1_k127_1039483_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.24e-207 669.0
PYH1_k127_1039483_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000006885 113.0
PYH1_k127_1039483_21 Bacterial regulatory proteins, crp family K10914 - - 0.000000000000001227 83.0
PYH1_k127_1039483_22 Glutathione S-transferase K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.00000000005126 66.0
PYH1_k127_1039483_23 Serine aminopeptidase, S33 - - - 0.0002115 47.0
PYH1_k127_1039483_3 Methionine synthase K00549 - 2.1.1.14 7.069e-195 616.0
PYH1_k127_1039483_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 592.0
PYH1_k127_1039483_5 Mandelate Racemase Muconate Lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 483.0
PYH1_k127_1039483_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 482.0
PYH1_k127_1039483_7 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 422.0
PYH1_k127_1039483_8 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 410.0
PYH1_k127_1039483_9 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 342.0
PYH1_k127_1046336_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 2.1e-207 649.0
PYH1_k127_1046336_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000004942 150.0
PYH1_k127_1046336_2 Protein of unknown function (DUF2442) - - - 0.0000000001388 64.0
PYH1_k127_1046336_3 Histone H1-like nucleoprotein HC2 K11275 - - 0.0000002959 56.0
PYH1_k127_1121817_0 CoA-binding domain protein K09181 - - 2.728e-209 662.0
PYH1_k127_1121817_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 503.0
PYH1_k127_1121817_2 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 493.0
PYH1_k127_1121817_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 379.0
PYH1_k127_1121817_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007391 277.0
PYH1_k127_1121817_5 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000485 251.0
PYH1_k127_1121817_6 lactoylglutathione lyase activity K08234 - - 0.00000000000000000000000000003577 132.0
PYH1_k127_1147345_0 Hydantoinase B/oxoprolinase - - - 1.08e-286 891.0
PYH1_k127_1147345_1 AMP-binding enzyme C-terminal domain K00666 - - 5.707e-227 715.0
PYH1_k127_1147345_10 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001285 296.0
PYH1_k127_1147345_11 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
PYH1_k127_1147345_12 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004046 274.0
PYH1_k127_1147345_13 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007673 273.0
PYH1_k127_1147345_14 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002569 272.0
PYH1_k127_1147345_15 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000005422 271.0
PYH1_k127_1147345_16 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005523 247.0
PYH1_k127_1147345_17 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003108 247.0
PYH1_k127_1147345_18 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000003212 248.0
PYH1_k127_1147345_19 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000006298 237.0
PYH1_k127_1147345_2 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 489.0
PYH1_k127_1147345_20 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000003612 205.0
PYH1_k127_1147345_21 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000001829 162.0
PYH1_k127_1147345_3 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 422.0
PYH1_k127_1147345_4 L-phenylalanine transmembrane transporter activity K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 400.0
PYH1_k127_1147345_5 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 392.0
PYH1_k127_1147345_6 protein-(glutamine-N5) methyltransferase activity K21786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 380.0
PYH1_k127_1147345_7 Abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 368.0
PYH1_k127_1147345_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 309.0
PYH1_k127_1147345_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 310.0
PYH1_k127_1210880_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 596.0
PYH1_k127_1210880_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 559.0
PYH1_k127_1210880_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 316.0
PYH1_k127_1210880_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001271 281.0
PYH1_k127_1210880_12 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001652 257.0
PYH1_k127_1210880_13 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000003773 219.0
PYH1_k127_1210880_14 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000001328 140.0
PYH1_k127_1210880_15 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000963 108.0
PYH1_k127_1210880_16 LTXXQ motif family protein - - - 0.0000000000008583 78.0
PYH1_k127_1210880_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 554.0
PYH1_k127_1210880_3 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 500.0
PYH1_k127_1210880_4 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 488.0
PYH1_k127_1210880_5 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 452.0
PYH1_k127_1210880_6 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 388.0
PYH1_k127_1210880_7 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 363.0
PYH1_k127_1210880_8 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 364.0
PYH1_k127_1210880_9 response regulator K02483,K07661,K18073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 334.0
PYH1_k127_1212874_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 2.85e-277 865.0
PYH1_k127_1212874_1 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000001148 196.0
PYH1_k127_1223302_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008577 252.0
PYH1_k127_1223302_1 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000816 181.0
PYH1_k127_1251390_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 379.0
PYH1_k127_1251390_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 308.0
PYH1_k127_1271437_0 COG0457 FOG TPR repeat - - - 2.639e-222 701.0
PYH1_k127_1271437_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 560.0
PYH1_k127_1271437_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000002839 168.0
PYH1_k127_1271437_11 Sterol carrier protein - - - 0.0000000000000001738 85.0
PYH1_k127_1271437_2 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 391.0
PYH1_k127_1271437_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 384.0
PYH1_k127_1271437_4 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 398.0
PYH1_k127_1271437_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 332.0
PYH1_k127_1271437_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 291.0
PYH1_k127_1271437_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 314.0
PYH1_k127_1271437_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002455 275.0
PYH1_k127_1271437_9 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009997 251.0
PYH1_k127_1273537_0 Acyl-CoA dehydrogenase N terminal K20035 - - 3.109e-246 788.0
PYH1_k127_1273537_1 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 601.0
PYH1_k127_1273537_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 456.0
PYH1_k127_1273537_3 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 453.0
PYH1_k127_1273537_4 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 355.0
PYH1_k127_1273537_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000001914 53.0
PYH1_k127_1278557_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.008e-201 655.0
PYH1_k127_1278557_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 531.0
PYH1_k127_1278557_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 521.0
PYH1_k127_1278557_3 Single-stranded-DNA-specific exonuclease K07462 - - 0.000000000000000000000000000000000000000000000000000000000006819 211.0
PYH1_k127_1278557_4 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000007944 180.0
PYH1_k127_1278557_5 Cyclophilin-like K09143 - - 0.00000000000000000000000000001838 132.0
PYH1_k127_1278557_6 KTSC domain - - - 0.0000003248 60.0
PYH1_k127_1278557_7 17 kDa surface antigen - - - 0.0007658 47.0
PYH1_k127_1303648_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.675e-201 639.0
PYH1_k127_1303648_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 451.0
PYH1_k127_1303648_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004538 261.0
PYH1_k127_1303648_3 Solute carrier family 35 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001248 254.0
PYH1_k127_1312202_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 551.0
PYH1_k127_1312202_1 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003281 284.0
PYH1_k127_1312202_2 Including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000005859 51.0
PYH1_k127_1322739_0 polysaccharide export protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 563.0
PYH1_k127_1322739_1 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 361.0
PYH1_k127_1325638_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1565.0
PYH1_k127_1325638_1 Participates in both transcription termination and antitermination K02600 - - 7.229e-217 690.0
PYH1_k127_1325638_10 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000001722 205.0
PYH1_k127_1325638_11 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000001453 172.0
PYH1_k127_1325638_12 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000002989 147.0
PYH1_k127_1325638_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 6.027e-205 655.0
PYH1_k127_1325638_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 356.0
PYH1_k127_1325638_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 349.0
PYH1_k127_1325638_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 324.0
PYH1_k127_1325638_6 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 289.0
PYH1_k127_1325638_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001008 287.0
PYH1_k127_1325638_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007486 264.0
PYH1_k127_1325638_9 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008061 268.0
PYH1_k127_1326560_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.822e-233 728.0
PYH1_k127_1326560_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 532.0
PYH1_k127_1326560_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
PYH1_k127_1326560_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000003567 216.0
PYH1_k127_1326560_12 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000001574 201.0
PYH1_k127_1326560_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000001083 188.0
PYH1_k127_1326560_14 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000002912 189.0
PYH1_k127_1326560_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000009286 181.0
PYH1_k127_1326560_16 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000001179 172.0
PYH1_k127_1326560_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000002966 154.0
PYH1_k127_1326560_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000006653 137.0
PYH1_k127_1326560_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000001487 134.0
PYH1_k127_1326560_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 341.0
PYH1_k127_1326560_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000008884 120.0
PYH1_k127_1326560_21 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000008734 89.0
PYH1_k127_1326560_22 Ribosomal protein L30 K02907 - - 0.00000000000000001867 84.0
PYH1_k127_1326560_23 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000006153 68.0
PYH1_k127_1326560_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 329.0
PYH1_k127_1326560_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 300.0
PYH1_k127_1326560_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 280.0
PYH1_k127_1326560_6 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001501 273.0
PYH1_k127_1326560_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001452 265.0
PYH1_k127_1326560_8 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000263 239.0
PYH1_k127_1326560_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000001287 220.0
PYH1_k127_1342790_0 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 455.0
PYH1_k127_1342790_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 458.0
PYH1_k127_1342790_2 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006566 298.0
PYH1_k127_1342790_3 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001644 252.0
PYH1_k127_1342815_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 1.521e-255 799.0
PYH1_k127_1342815_1 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.00000000000000000003248 90.0
PYH1_k127_138179_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 416.0
PYH1_k127_138179_1 - - - - 0.0000000000000000000000000000000000000000001092 179.0
PYH1_k127_1392161_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1244.0
PYH1_k127_1392161_1 His Kinase A (phospho-acceptor) domain - - - 0.0 1208.0
PYH1_k127_1392161_10 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 518.0
PYH1_k127_1392161_11 binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 423.0
PYH1_k127_1392161_12 PFAM AFG1-family ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 443.0
PYH1_k127_1392161_13 Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 396.0
PYH1_k127_1392161_14 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 404.0
PYH1_k127_1392161_15 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 398.0
PYH1_k127_1392161_16 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 392.0
PYH1_k127_1392161_17 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 369.0
PYH1_k127_1392161_18 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 306.0
PYH1_k127_1392161_19 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 285.0
PYH1_k127_1392161_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1052.0
PYH1_k127_1392161_20 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004071 289.0
PYH1_k127_1392161_21 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002894 286.0
PYH1_k127_1392161_22 Haem-degrading - - - 0.0000000000000000000000000000000000000000000002069 179.0
PYH1_k127_1392161_23 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000002743 169.0
PYH1_k127_1392161_24 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000004064 177.0
PYH1_k127_1392161_25 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000004272 152.0
PYH1_k127_1392161_26 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000004311 151.0
PYH1_k127_1392161_27 Haem-degrading - - - 0.0000000000000000000000000000000005148 145.0
PYH1_k127_1392161_28 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000004219 127.0
PYH1_k127_1392161_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 3.438e-292 924.0
PYH1_k127_1392161_30 - - - - 0.000000000000000004971 87.0
PYH1_k127_1392161_31 - - - - 0.00000000000000002085 83.0
PYH1_k127_1392161_32 - - - - 0.0000000000000007053 86.0
PYH1_k127_1392161_34 - - - - 0.000001624 53.0
PYH1_k127_1392161_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.649e-282 883.0
PYH1_k127_1392161_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 7.615e-256 799.0
PYH1_k127_1392161_6 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 6.035e-195 617.0
PYH1_k127_1392161_7 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 592.0
PYH1_k127_1392161_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 578.0
PYH1_k127_1392161_9 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 552.0
PYH1_k127_1400050_0 FAD linked oxidase domain protein K06911 - - 0.0 1203.0
PYH1_k127_1400050_1 luciferase - - - 0.000000000000000000000000000000000000000000000000000000000000002735 224.0
PYH1_k127_1400050_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000007304 185.0
PYH1_k127_1400050_3 Ankyrin repeat and kinase domain containing 1 K16289 - 2.7.11.1 0.000000000000000000000936 110.0
PYH1_k127_1400050_4 COG0501 Zn-dependent protease with chaperone function K03799 - - 0.0000000000001225 79.0
PYH1_k127_145403_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 443.0
PYH1_k127_145403_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 303.0
PYH1_k127_145403_2 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 302.0
PYH1_k127_145403_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000002585 188.0
PYH1_k127_145403_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000001578 159.0
PYH1_k127_145403_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000003192 137.0
PYH1_k127_145403_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000007891 79.0
PYH1_k127_145403_7 Stress responsive alpha-beta barrel domain protein - - - 0.0000000001803 62.0
PYH1_k127_1480476_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.774e-264 824.0
PYH1_k127_1480476_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 441.0
PYH1_k127_1480476_10 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000007517 107.0
PYH1_k127_1480476_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 426.0
PYH1_k127_1480476_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 399.0
PYH1_k127_1480476_4 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 360.0
PYH1_k127_1480476_5 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000003081 250.0
PYH1_k127_1480476_6 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000001212 229.0
PYH1_k127_1480476_7 rieske 2fe-2s - - - 0.0000000000000000000000000000001702 132.0
PYH1_k127_1480476_8 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.0000000000000000000000000002476 117.0
PYH1_k127_1480476_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000006556 108.0
PYH1_k127_1518247_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.286e-228 719.0
PYH1_k127_1518247_1 - - - - 0.0000000000000000000000006995 109.0
PYH1_k127_1523429_0 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 585.0
PYH1_k127_1523429_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 484.0
PYH1_k127_1523429_10 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007021 339.0
PYH1_k127_1523429_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 345.0
PYH1_k127_1523429_12 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 329.0
PYH1_k127_1523429_13 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 288.0
PYH1_k127_1523429_14 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000019 205.0
PYH1_k127_1523429_15 Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only K02503 - - 0.00000000000000000000000000000000000000000001197 168.0
PYH1_k127_1523429_16 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.0000000000000000000000000000000001167 138.0
PYH1_k127_1523429_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000002696 120.0
PYH1_k127_1523429_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000005632 105.0
PYH1_k127_1523429_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 440.0
PYH1_k127_1523429_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 418.0
PYH1_k127_1523429_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 412.0
PYH1_k127_1523429_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 396.0
PYH1_k127_1523429_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 385.0
PYH1_k127_1523429_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 380.0
PYH1_k127_1523429_8 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 364.0
PYH1_k127_1523429_9 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 364.0
PYH1_k127_1526589_0 acyl-CoA dehydrogenase K06445 - - 6.768e-317 1002.0
PYH1_k127_1526589_1 ABC transporter transmembrane region K06147 - - 1.992e-237 748.0
PYH1_k127_1526589_2 Belongs to the thiolase family K00626 - 2.3.1.9 7.399e-202 635.0
PYH1_k127_1526589_3 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 399.0
PYH1_k127_1526589_4 Methyltransferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 328.0
PYH1_k127_1526589_5 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 299.0
PYH1_k127_1526589_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
PYH1_k127_1537244_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 7.793e-273 853.0
PYH1_k127_1537244_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 535.0
PYH1_k127_1537244_10 Transcriptional regulator - - - 0.00000000000000000002516 94.0
PYH1_k127_1537244_2 Beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 497.0
PYH1_k127_1537244_3 transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 419.0
PYH1_k127_1537244_4 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 402.0
PYH1_k127_1537244_5 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000011 285.0
PYH1_k127_1537244_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000002386 234.0
PYH1_k127_1537244_7 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000003184 243.0
PYH1_k127_1537244_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000807 220.0
PYH1_k127_1537244_9 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000004259 195.0
PYH1_k127_1544921_0 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 567.0
PYH1_k127_1544921_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 437.0
PYH1_k127_1544921_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 320.0
PYH1_k127_1544921_3 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 343.0
PYH1_k127_1544921_4 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 332.0
PYH1_k127_1544921_5 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 289.0
PYH1_k127_1544921_6 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000001824 188.0
PYH1_k127_1544921_7 arginine transmembrane transporter activity - - - 0.0000000000000000000000000000000000000001304 173.0
PYH1_k127_1544921_8 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000001254 117.0
PYH1_k127_154669_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.944e-255 791.0
PYH1_k127_154669_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 360.0
PYH1_k127_154669_2 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000001679 243.0
PYH1_k127_154669_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000002532 190.0
PYH1_k127_154669_4 NAD(P) transhydrogenase beta subunit - - - 0.00000000000000000000005181 115.0
PYH1_k127_154669_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000094 74.0
PYH1_k127_154669_6 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000003778 56.0
PYH1_k127_155943_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 388.0
PYH1_k127_1561244_0 Peptidase M50 K16922 - - 1.314e-196 640.0
PYH1_k127_1561244_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 339.0
PYH1_k127_1561244_2 SecA preprotein cross-linking domain K03070 - - 0.000000000000000000000000000000000000000000000000007879 207.0
PYH1_k127_1565084_0 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 564.0
PYH1_k127_1565084_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 340.0
PYH1_k127_1565084_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000133 113.0
PYH1_k127_1565084_11 TetR Family - - - 0.00000000000000000000000005289 111.0
PYH1_k127_1565084_12 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000008018 111.0
PYH1_k127_1565084_13 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.0000000000000000003643 103.0
PYH1_k127_1565084_14 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000003665 60.0
PYH1_k127_1565084_2 amp-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 314.0
PYH1_k127_1565084_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 312.0
PYH1_k127_1565084_4 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004089 242.0
PYH1_k127_1565084_5 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000001519 220.0
PYH1_k127_1565084_6 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000000000000000000000000005788 188.0
PYH1_k127_1565084_7 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000001111 180.0
PYH1_k127_1565084_8 membrane - - - 0.0000000000000000000000000000000000000000005382 164.0
PYH1_k127_1565084_9 Outer membrane lipoprotein carrier protein LolA - - - 0.000000000000000000000000000003667 132.0
PYH1_k127_1570013_0 PQQ enzyme repeat - - - 4.404e-303 937.0
PYH1_k127_1570013_1 TonB-dependent Receptor Plug Domain K02014 - - 9.356e-216 691.0
PYH1_k127_1570013_10 PFAM Ankyrin K06867 - - 0.000000000000000000000000000000000000000000000000000003349 198.0
PYH1_k127_1570013_11 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000000000313 171.0
PYH1_k127_1570013_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000005287 151.0
PYH1_k127_1570013_13 cytochrome - - - 0.000001773 55.0
PYH1_k127_1570013_2 TonB-dependent receptor K02014 - - 1.691e-202 675.0
PYH1_k127_1570013_3 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 586.0
PYH1_k127_1570013_4 40-residue YVTN family beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 394.0
PYH1_k127_1570013_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
PYH1_k127_1570013_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 324.0
PYH1_k127_1570013_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 322.0
PYH1_k127_1570013_8 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006323 282.0
PYH1_k127_1570013_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000366 245.0
PYH1_k127_1595307_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 440.0
PYH1_k127_1595307_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 369.0
PYH1_k127_1595307_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000004086 191.0
PYH1_k127_1596678_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.04e-322 994.0
PYH1_k127_1596678_1 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 561.0
PYH1_k127_1596678_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001147 275.0
PYH1_k127_1596678_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 264.0
PYH1_k127_1596678_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000006421 188.0
PYH1_k127_1596678_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000003081 96.0
PYH1_k127_1596678_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000002613 80.0
PYH1_k127_1607581_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 1.674e-202 640.0
PYH1_k127_1607581_1 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 372.0
PYH1_k127_1607581_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 361.0
PYH1_k127_1607581_3 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000009923 223.0
PYH1_k127_1607581_4 - - - - 0.0000000000000000000000004644 111.0
PYH1_k127_1607581_6 Cysteine rich repeat K06816 GO:0000137,GO:0000138,GO:0000139,GO:0001501,GO:0002376,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005797,GO:0005886,GO:0006810,GO:0006886,GO:0006928,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009887,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010955,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016477,GO:0017015,GO:0017134,GO:0019222,GO:0019838,GO:0023051,GO:0023057,GO:0030162,GO:0030512,GO:0031012,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031984,GO:0031985,GO:0032268,GO:0032269,GO:0032330,GO:0032501,GO:0032502,GO:0033036,GO:0034613,GO:0040011,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045861,GO:0046907,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050900,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051641,GO:0051649,GO:0051674,GO:0060255,GO:0060348,GO:0060349,GO:0061035,GO:0065007,GO:0070613,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0080090,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0098588,GO:0098791,GO:1903317,GO:1903318,GO:1903844,GO:1903845,GO:2000026 - 0.00000001409 63.0
PYH1_k127_1611903_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 589.0
PYH1_k127_1611903_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 501.0
PYH1_k127_1611903_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 419.0
PYH1_k127_1611903_3 MAPEG family - - - 0.00000000000000002605 86.0
PYH1_k127_1633094_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 3.585e-211 670.0
PYH1_k127_1633094_1 Penicillin amidase K01434 - 3.5.1.11 1.467e-203 665.0
PYH1_k127_1633094_2 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 564.0
PYH1_k127_1633094_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 471.0
PYH1_k127_1633094_4 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 436.0
PYH1_k127_1633094_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 410.0
PYH1_k127_1633094_6 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 387.0
PYH1_k127_1633094_7 branched-chain amino acid transport K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 356.0
PYH1_k127_1633094_8 Disulfide bond formation protein DsbB - - - 0.00000000000000000000000000000000000000000004137 170.0
PYH1_k127_1650536_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 456.0
PYH1_k127_1650536_1 NAD dependent epimerase dehydratase family protein K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000002025 90.0
PYH1_k127_1653933_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.519e-312 964.0
PYH1_k127_1653933_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.574e-222 704.0
PYH1_k127_1653933_10 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 329.0
PYH1_k127_1653933_11 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 326.0
PYH1_k127_1653933_12 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 298.0
PYH1_k127_1653933_13 negative regulator of sigma E activity K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005088 268.0
PYH1_k127_1653933_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000004523 265.0
PYH1_k127_1653933_15 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000009517 250.0
PYH1_k127_1653933_16 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000003794 229.0
PYH1_k127_1653933_17 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000007561 197.0
PYH1_k127_1653933_18 OmpA family - - - 0.000000000000000000000000000000000000000008129 160.0
PYH1_k127_1653933_19 FecR protein - - - 0.000000000000000000000000000000000000002213 151.0
PYH1_k127_1653933_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 602.0
PYH1_k127_1653933_20 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000004066 121.0
PYH1_k127_1653933_21 Histidine kinase-like ATPase domain - - - 0.000000000000000009214 92.0
PYH1_k127_1653933_22 Domain of unknown function (DUF4845) - - - 0.00000000000001056 86.0
PYH1_k127_1653933_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 498.0
PYH1_k127_1653933_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 411.0
PYH1_k127_1653933_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 400.0
PYH1_k127_1653933_6 TIGRFAM 3-hydroxybutyrate dehydrogenase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 376.0
PYH1_k127_1653933_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 386.0
PYH1_k127_1653933_8 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 360.0
PYH1_k127_1653933_9 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 342.0
PYH1_k127_1656071_0 PFAM AMP-dependent synthetase K01895 - 6.2.1.1 1.616e-262 842.0
PYH1_k127_1656071_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 521.0
PYH1_k127_1656071_11 Outer membrane lipoprotein LolB - - - 0.00001551 48.0
PYH1_k127_1656071_12 - - - - 0.0009522 42.0
PYH1_k127_1656071_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 511.0
PYH1_k127_1656071_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 456.0
PYH1_k127_1656071_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 374.0
PYH1_k127_1656071_5 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 326.0
PYH1_k127_1656071_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005864 250.0
PYH1_k127_1656071_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000518 232.0
PYH1_k127_1656071_8 - - - - 0.000000000000000000000004795 116.0
PYH1_k127_1656071_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000004405 83.0
PYH1_k127_1656885_0 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 312.0
PYH1_k127_1656885_1 Outer Membrane Lipoprotein K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000002343 241.0
PYH1_k127_1656885_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000005131 188.0
PYH1_k127_1681306_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.47e-291 908.0
PYH1_k127_1681306_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 586.0
PYH1_k127_1681306_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 555.0
PYH1_k127_1681306_3 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 342.0
PYH1_k127_1681306_4 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 352.0
PYH1_k127_1681306_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 297.0
PYH1_k127_1681306_6 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002722 268.0
PYH1_k127_1681306_7 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000005508 190.0
PYH1_k127_1681306_8 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000006646 120.0
PYH1_k127_170658_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.336e-195 620.0
PYH1_k127_170658_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000001953 221.0
PYH1_k127_170658_2 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000001354 77.0
PYH1_k127_170658_3 - - - - 0.0000000000008216 73.0
PYH1_k127_1744203_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.263e-289 913.0
PYH1_k127_1744203_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 2.399e-209 672.0
PYH1_k127_1744203_10 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000003091 107.0
PYH1_k127_1744203_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 511.0
PYH1_k127_1744203_3 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 498.0
PYH1_k127_1744203_4 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 447.0
PYH1_k127_1744203_5 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 403.0
PYH1_k127_1744203_6 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 350.0
PYH1_k127_1744203_7 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 324.0
PYH1_k127_1744203_8 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000002045 258.0
PYH1_k127_1744203_9 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000001184 207.0
PYH1_k127_1756661_0 AMP-dependent synthetase K01897 - 6.2.1.3 4.498e-201 643.0
PYH1_k127_1756661_1 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 346.0
PYH1_k127_1756661_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000008029 231.0
PYH1_k127_1756661_3 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000000000000003018 186.0
PYH1_k127_1756661_4 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000000000001342 143.0
PYH1_k127_1756661_5 MarC family integral membrane protein K05595 - - 0.000000000000000000000000002035 115.0
PYH1_k127_1758930_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 508.0
PYH1_k127_1758930_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000003961 239.0
PYH1_k127_1758930_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000112 89.0
PYH1_k127_1766656_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 565.0
PYH1_k127_1766656_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 459.0
PYH1_k127_1766656_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 442.0
PYH1_k127_1766656_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 332.0
PYH1_k127_1766656_4 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 331.0
PYH1_k127_1766656_5 PFAM Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA FabZ - - - 0.0000000000000000000000000000000000009993 149.0
PYH1_k127_1766656_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000009335 122.0
PYH1_k127_1766656_8 Protein of unknown function (DUF3261) - - - 0.000002154 60.0
PYH1_k127_1769027_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1144.0
PYH1_k127_1769027_1 CHASE2 K01768 - 4.6.1.1 4.237e-270 850.0
PYH1_k127_1769027_2 metal-dependent phosphohydrolase HD sub domain - - - 1.824e-238 749.0
PYH1_k127_1769027_3 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 449.0
PYH1_k127_1769027_4 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 363.0
PYH1_k127_1769027_5 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.000000000000000000000000000000000000000000007353 167.0
PYH1_k127_1769027_6 Belongs to the N-Me-Phe pilin family K02650,K02655 - - 0.00000000000000000000000000000000000000000001089 167.0
PYH1_k127_1769027_7 (FHA) domain - - - 0.000000000000000000000000000000000004421 139.0
PYH1_k127_1769027_8 - - - - 0.00000002117 61.0
PYH1_k127_1775003_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1097.0
PYH1_k127_1775003_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 2.169e-312 980.0
PYH1_k127_1775003_10 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000008203 232.0
PYH1_k127_1775003_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000101 218.0
PYH1_k127_1775003_12 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000006125 183.0
PYH1_k127_1775003_13 cytochrome c K17223 - - 0.000000000000000000000000000000000000000002743 170.0
PYH1_k127_1775003_14 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000002889 156.0
PYH1_k127_1775003_15 Sulphur oxidation protein SoxZ - - - 0.0000000000000000000000000000000000000265 145.0
PYH1_k127_1775003_16 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000006449 154.0
PYH1_k127_1775003_17 universal stress protein - - - 0.0000000000000000000000000000002849 130.0
PYH1_k127_1775003_18 dksA traR - - - 0.00000000000000000000000002374 113.0
PYH1_k127_1775003_19 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000008574 104.0
PYH1_k127_1775003_2 DNA polymerase X family K02347 - - 2.471e-228 720.0
PYH1_k127_1775003_20 - - - - 0.0000000000000000001323 93.0
PYH1_k127_1775003_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 524.0
PYH1_k127_1775003_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 505.0
PYH1_k127_1775003_5 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 466.0
PYH1_k127_1775003_6 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 437.0
PYH1_k127_1775003_7 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 419.0
PYH1_k127_1775003_8 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 388.0
PYH1_k127_1775003_9 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 331.0
PYH1_k127_1796642_0 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 333.0
PYH1_k127_1796642_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000933 244.0
PYH1_k127_1796642_10 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00001497 57.0
PYH1_k127_1796642_11 Cytochrome c class - - - 0.0002803 54.0
PYH1_k127_1796642_2 - - - - 0.00000000000000000000000000000000000000000000000000438 199.0
PYH1_k127_1796642_3 cytochrome c5 - - - 0.00000000000000000000000000000000000000000000003012 184.0
PYH1_k127_1796642_4 Cytochrome c - - - 0.00000000000000000000000006548 124.0
PYH1_k127_1796642_5 - - - - 0.00000000000000000004366 103.0
PYH1_k127_1796642_6 cytochrome - - - 0.0000000000000000000438 103.0
PYH1_k127_1796642_7 Psort location Periplasmic, score - - - 0.00000000000001468 86.0
PYH1_k127_1796642_8 PFAM cytochrome c, class I K08738 - - 0.0000000000006263 73.0
PYH1_k127_1796642_9 Cytochrome c K08738 - - 0.000000003226 62.0
PYH1_k127_1803297_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 8.885e-213 684.0
PYH1_k127_1803297_1 Phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 505.0
PYH1_k127_1803297_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 412.0
PYH1_k127_1803297_3 phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 289.0
PYH1_k127_1803297_4 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000001976 130.0
PYH1_k127_1803297_5 PFAM CoA-transferase family III K01796 - 5.1.99.4 0.000408 43.0
PYH1_k127_1827433_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1221.0
PYH1_k127_1827433_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 3.602e-284 896.0
PYH1_k127_1827433_10 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000136 50.0
PYH1_k127_1827433_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 6.659e-231 723.0
PYH1_k127_1827433_3 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 604.0
PYH1_k127_1827433_4 PFAM O-methyltransferase, family 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001451 282.0
PYH1_k127_1827433_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.000000000000000000000000000000000000000000000000111 183.0
PYH1_k127_1827433_6 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000000001651 160.0
PYH1_k127_1827433_7 membrane - - - 0.000000000000000000000000000000000002746 142.0
PYH1_k127_1827433_8 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000003481 141.0
PYH1_k127_1827433_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000001411 96.0
PYH1_k127_1843736_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 1.576e-230 724.0
PYH1_k127_1843736_1 Cysteine-rich domain - - - 7.377e-221 692.0
PYH1_k127_1843736_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 427.0
PYH1_k127_1843736_11 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 397.0
PYH1_k127_1843736_12 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
PYH1_k127_1843736_13 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 365.0
PYH1_k127_1843736_14 cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 357.0
PYH1_k127_1843736_15 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 349.0
PYH1_k127_1843736_16 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008511 261.0
PYH1_k127_1843736_17 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000001139 212.0
PYH1_k127_1843736_18 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000008403 209.0
PYH1_k127_1843736_19 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000132 194.0
PYH1_k127_1843736_2 Aminotransferase K14261 - - 1.566e-220 687.0
PYH1_k127_1843736_20 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000000001024 184.0
PYH1_k127_1843736_21 FecR protein - - - 0.000000000000000000000000000000000000000001708 166.0
PYH1_k127_1843736_22 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000007202 155.0
PYH1_k127_1843736_23 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000000001504 136.0
PYH1_k127_1843736_24 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000002129 137.0
PYH1_k127_1843736_25 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000007097 149.0
PYH1_k127_1843736_26 Vibrio cholerae RfbT protein - - - 0.00000000000000000004083 102.0
PYH1_k127_1843736_27 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000003526 84.0
PYH1_k127_1843736_28 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0003116 44.0
PYH1_k127_1843736_3 homoserine dehydrogenase K00003 - 1.1.1.3 1.177e-200 653.0
PYH1_k127_1843736_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.132e-198 627.0
PYH1_k127_1843736_5 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 611.0
PYH1_k127_1843736_6 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 578.0
PYH1_k127_1843736_7 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 545.0
PYH1_k127_1843736_8 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 514.0
PYH1_k127_1843736_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 433.0
PYH1_k127_2000203_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 3.926e-307 959.0
PYH1_k127_2000203_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.416e-237 756.0
PYH1_k127_2000203_10 Smr domain - - - 0.000000009629 63.0
PYH1_k127_2000203_11 receptor - - - 0.0001815 45.0
PYH1_k127_2000203_2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 5.189e-207 650.0
PYH1_k127_2000203_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 507.0
PYH1_k127_2000203_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 508.0
PYH1_k127_2000203_5 Hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 419.0
PYH1_k127_2000203_6 Nucleoside-binding outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 340.0
PYH1_k127_2000203_7 Transcriptional regulator crp fnr family K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
PYH1_k127_2000203_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
PYH1_k127_2000203_9 FecR protein - - - 0.0000000000000000000000000000000000000000000000006857 183.0
PYH1_k127_2014087_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 466.0
PYH1_k127_2014087_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 399.0
PYH1_k127_2014087_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000043 153.0
PYH1_k127_2014087_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000001428 150.0
PYH1_k127_2014087_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000004396 136.0
PYH1_k127_2014087_5 KR domain - - - 0.0000001604 54.0
PYH1_k127_2026917_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 284.0
PYH1_k127_2026917_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000004129 211.0
PYH1_k127_2026917_2 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000006107 72.0
PYH1_k127_2059804_0 Patatin-like phospholipase K07001 - - 2.182e-262 824.0
PYH1_k127_2059804_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 6.33e-209 655.0
PYH1_k127_2059804_2 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 325.0
PYH1_k127_2059804_3 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001373 289.0
PYH1_k127_2059804_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002638 259.0
PYH1_k127_2059804_5 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000001803 160.0
PYH1_k127_2059804_6 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000001503 59.0
PYH1_k127_2121233_0 Atp-dependent helicase K03578 - 3.6.4.13 1.5e-323 1014.0
PYH1_k127_2123167_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.562e-195 622.0
PYH1_k127_2123167_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 469.0
PYH1_k127_2123167_2 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000004741 98.0
PYH1_k127_2130339_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 478.0
PYH1_k127_2130339_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 376.0
PYH1_k127_215424_0 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 571.0
PYH1_k127_215424_1 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000006598 168.0
PYH1_k127_2194080_0 Putative modulator of DNA gyrase K03568 - - 5.6e-219 703.0
PYH1_k127_2194080_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 350.0
PYH1_k127_2194080_2 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 339.0
PYH1_k127_2194080_3 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000001355 251.0
PYH1_k127_2204774_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1077.0
PYH1_k127_2204774_1 Adenylate and Guanylate cyclase catalytic domain - - - 1.878e-273 876.0
PYH1_k127_2204774_10 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 419.0
PYH1_k127_2204774_11 AsmA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 430.0
PYH1_k127_2204774_12 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 365.0
PYH1_k127_2204774_13 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 327.0
PYH1_k127_2204774_14 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 333.0
PYH1_k127_2204774_15 Putative methyltransferase K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001205 295.0
PYH1_k127_2204774_16 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000575 217.0
PYH1_k127_2204774_17 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000000000001681 220.0
PYH1_k127_2204774_18 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000003655 182.0
PYH1_k127_2204774_19 OsmC-like protein - - - 0.0000000000000000000000000000000000000106 152.0
PYH1_k127_2204774_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 2.38e-235 738.0
PYH1_k127_2204774_20 sigma 54 modulation protein K05808 - - 0.00000000000000000000000000001451 134.0
PYH1_k127_2204774_21 ThiS family K03154 - - 0.00000000000000000002463 92.0
PYH1_k127_2204774_22 - - - - 0.0001856 53.0
PYH1_k127_2204774_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 499.0
PYH1_k127_2204774_4 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 490.0
PYH1_k127_2204774_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 473.0
PYH1_k127_2204774_6 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 466.0
PYH1_k127_2204774_7 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 456.0
PYH1_k127_2204774_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 449.0
PYH1_k127_2204774_9 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 437.0
PYH1_k127_2208417_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 5.331e-197 633.0
PYH1_k127_2208417_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 586.0
PYH1_k127_2208417_2 protein conserved in bacteria K03690 - - 0.00000000000000000001465 96.0
PYH1_k127_2208417_3 PFAM VanZ family protein - - - 0.0000000000000000001871 89.0
PYH1_k127_2211892_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.934e-292 905.0
PYH1_k127_2211892_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 553.0
PYH1_k127_2211892_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH1_k127_2211892_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000001391 246.0
PYH1_k127_2211892_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000001401 172.0
PYH1_k127_2211892_5 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000000000002054 81.0
PYH1_k127_2223975_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.15e-205 647.0
PYH1_k127_2223975_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009649 271.0
PYH1_k127_2244576_0 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 310.0
PYH1_k127_2244576_1 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 304.0
PYH1_k127_2244576_10 Lipase (class 3) - - - 0.0000106 59.0
PYH1_k127_2244576_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 295.0
PYH1_k127_2244576_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008671 296.0
PYH1_k127_2244576_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001506 228.0
PYH1_k127_2244576_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000482 191.0
PYH1_k127_2244576_6 - - - - 0.000000000000000000000000000000000000000388 157.0
PYH1_k127_2244576_7 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000003071 131.0
PYH1_k127_2244576_8 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000248 128.0
PYH1_k127_2244576_9 - - - - 0.00000000001836 68.0
PYH1_k127_2253607_0 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 526.0
PYH1_k127_2253607_1 HD domain K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
PYH1_k127_2253607_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001888 265.0
PYH1_k127_2327554_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
PYH1_k127_2327554_1 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005699 269.0
PYH1_k127_2327554_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000005737 121.0
PYH1_k127_2327554_3 Adenylate cyclase - - - 0.0000000000005094 74.0
PYH1_k127_2380502_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 4.493e-255 797.0
PYH1_k127_2380502_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 479.0
PYH1_k127_2380502_10 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000002802 134.0
PYH1_k127_2380502_11 Bacterial membrane protein YfhO - - - 0.0000001079 64.0
PYH1_k127_2380502_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 410.0
PYH1_k127_2380502_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 321.0
PYH1_k127_2380502_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 304.0
PYH1_k127_2380502_5 Thiosulfate-oxidizing multienzyme system protein SoxA K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 288.0
PYH1_k127_2380502_6 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000001918 257.0
PYH1_k127_2380502_7 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000001148 186.0
PYH1_k127_2380502_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000001084 195.0
PYH1_k127_2380502_9 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000002303 177.0
PYH1_k127_2391455_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 534.0
PYH1_k127_2391455_1 MraW methylase family K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 365.0
PYH1_k127_2391455_2 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 342.0
PYH1_k127_2391455_3 Permease MlaE - - - 0.00000000000000000000000000000000000000000000000001245 186.0
PYH1_k127_2391455_4 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000541 157.0
PYH1_k127_2391455_5 - - - - 0.00000000000000000000000000000000000000005851 169.0
PYH1_k127_2391455_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000005921 101.0
PYH1_k127_239715_0 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001249 287.0
PYH1_k127_239715_1 enzyme of heme biosynthesis K02498 - - 0.00000000000000000000000000000000000004669 152.0
PYH1_k127_239715_2 synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000003646 135.0
PYH1_k127_243738_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1468.0
PYH1_k127_243738_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000001699 190.0
PYH1_k127_243738_2 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000004064 146.0
PYH1_k127_2459039_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1455.0
PYH1_k127_2459039_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 604.0
PYH1_k127_2459039_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000001422 124.0
PYH1_k127_2459039_12 Metal-sensitive transcriptional repressor - - - 0.000000000000001517 79.0
PYH1_k127_2459039_2 PFAM monooxygenase FAD-binding K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 530.0
PYH1_k127_2459039_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 508.0
PYH1_k127_2459039_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 483.0
PYH1_k127_2459039_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 394.0
PYH1_k127_2459039_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 365.0
PYH1_k127_2459039_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 329.0
PYH1_k127_2459039_8 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 327.0
PYH1_k127_2459039_9 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000007227 152.0
PYH1_k127_2497616_0 PFAM Sulfatase - - - 0.0 1215.0
PYH1_k127_2497616_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.315e-285 882.0
PYH1_k127_2497616_10 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000002713 207.0
PYH1_k127_2497616_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000004653 171.0
PYH1_k127_2497616_2 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 6.263e-270 847.0
PYH1_k127_2497616_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 540.0
PYH1_k127_2497616_4 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 462.0
PYH1_k127_2497616_5 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 436.0
PYH1_k127_2497616_6 protein conserved in bacteria K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 371.0
PYH1_k127_2497616_7 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 346.0
PYH1_k127_2497616_8 response regulator K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 338.0
PYH1_k127_2497616_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004962 293.0
PYH1_k127_251373_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 5.642e-266 831.0
PYH1_k127_251373_1 GMC oxidoreductase K00108 - 1.1.99.1 7.666e-241 753.0
PYH1_k127_251373_10 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 572.0
PYH1_k127_251373_11 Dehydrogenase K15515 - 1.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 579.0
PYH1_k127_251373_12 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 565.0
PYH1_k127_251373_13 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 535.0
PYH1_k127_251373_14 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 465.0
PYH1_k127_251373_15 Product type K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 486.0
PYH1_k127_251373_16 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 454.0
PYH1_k127_251373_17 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 354.0
PYH1_k127_251373_18 belongs to the CobB CobQ family K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 310.0
PYH1_k127_251373_19 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 321.0
PYH1_k127_251373_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.683e-205 677.0
PYH1_k127_251373_20 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 285.0
PYH1_k127_251373_21 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000156 270.0
PYH1_k127_251373_22 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
PYH1_k127_251373_23 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000004004 224.0
PYH1_k127_251373_24 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000002559 214.0
PYH1_k127_251373_25 - - - - 0.000000000000000000000000000000000000000002936 162.0
PYH1_k127_251373_26 Universal stress protein family - - - 0.000000000000000000000000000000000000169 152.0
PYH1_k127_251373_28 Protein conserved in bacteria - - - 0.0000000000000000000000000000006447 143.0
PYH1_k127_251373_3 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 1.749e-203 650.0
PYH1_k127_251373_30 - - - - 0.0000004605 59.0
PYH1_k127_251373_31 short-chain dehydrogenase - - - 0.00001061 54.0
PYH1_k127_251373_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 608.0
PYH1_k127_251373_5 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 618.0
PYH1_k127_251373_6 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 616.0
PYH1_k127_251373_7 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 585.0
PYH1_k127_251373_8 Long-chain fatty acid--CoA ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 588.0
PYH1_k127_251373_9 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 570.0
PYH1_k127_2531447_0 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000002032 256.0
PYH1_k127_2531447_1 FecR protein - - - 0.000000000000000004958 96.0
PYH1_k127_2538506_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 543.0
PYH1_k127_2538506_1 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 422.0
PYH1_k127_2538506_2 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 338.0
PYH1_k127_2538506_3 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006496 237.0
PYH1_k127_2538506_4 COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - 0.00000000000000001333 89.0
PYH1_k127_2538506_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0001024 46.0
PYH1_k127_2554688_0 amino acid K01996,K11958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 330.0
PYH1_k127_2554688_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 302.0
PYH1_k127_2554688_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000003468 147.0
PYH1_k127_255503_0 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 369.0
PYH1_k127_255503_1 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 325.0
PYH1_k127_255503_2 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 301.0
PYH1_k127_255503_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000002853 229.0
PYH1_k127_255503_4 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000009405 197.0
PYH1_k127_255503_5 Belongs to the GMC oxidoreductase family - - - 0.0000000000000000000000000000000008123 132.0
PYH1_k127_255503_6 cytochrome - - - 0.00000000000000001765 93.0
PYH1_k127_2592193_0 PFAM extracellular solute-binding protein family 1 K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 565.0
PYH1_k127_2592193_1 Bacterial extracellular solute-binding protein K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 458.0
PYH1_k127_2592193_10 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000001203 115.0
PYH1_k127_2592193_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 440.0
PYH1_k127_2592193_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 433.0
PYH1_k127_2592193_4 transporter permease K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 422.0
PYH1_k127_2592193_5 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 407.0
PYH1_k127_2592193_6 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 343.0
PYH1_k127_2592193_7 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000004253 254.0
PYH1_k127_2592193_8 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000287 201.0
PYH1_k127_2592193_9 Small MutS-related domain - - - 0.0000000000000000000000000000000004375 133.0
PYH1_k127_2607057_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 4.385e-298 947.0
PYH1_k127_2607057_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 481.0
PYH1_k127_2607057_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000003881 196.0
PYH1_k127_2607057_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000008543 175.0
PYH1_k127_2607057_4 PFAM regulatory protein MerR - - - 0.000000000000000000000000000000000000000000000001373 180.0
PYH1_k127_2608588_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2410.0
PYH1_k127_2608588_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 7.224e-311 983.0
PYH1_k127_2608588_10 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 379.0
PYH1_k127_2608588_11 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 368.0
PYH1_k127_2608588_12 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 373.0
PYH1_k127_2608588_13 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 356.0
PYH1_k127_2608588_14 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 354.0
PYH1_k127_2608588_15 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 328.0
PYH1_k127_2608588_16 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 312.0
PYH1_k127_2608588_17 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 317.0
PYH1_k127_2608588_18 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003816 258.0
PYH1_k127_2608588_19 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000008681 228.0
PYH1_k127_2608588_2 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 5.24e-256 796.0
PYH1_k127_2608588_20 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000005633 217.0
PYH1_k127_2608588_21 NnrU protein - - - 0.00000000000000000000000000000000000000000000000001124 187.0
PYH1_k127_2608588_22 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000000000004881 197.0
PYH1_k127_2608588_23 Thioesterase - - - 0.00000000000000000000000000000000000002341 149.0
PYH1_k127_2608588_24 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000001542 134.0
PYH1_k127_2608588_25 Outer membrane protein beta-barrel domain - - - 0.0000000000001493 83.0
PYH1_k127_2608588_26 Beta-lactamase K01069 - 3.1.2.6 0.000000002312 59.0
PYH1_k127_2608588_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 7.318e-222 702.0
PYH1_k127_2608588_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 563.0
PYH1_k127_2608588_5 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 542.0
PYH1_k127_2608588_6 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 529.0
PYH1_k127_2608588_7 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 475.0
PYH1_k127_2608588_8 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 470.0
PYH1_k127_2608588_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 377.0
PYH1_k127_2611173_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000385 286.0
PYH1_k127_2611173_1 serine threonine protein kinase K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000471 209.0
PYH1_k127_2611173_2 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0000000000000000000000000000000005381 132.0
PYH1_k127_2611173_3 (Hpt) domain - - - 0.000000000000000003832 87.0
PYH1_k127_2614447_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1560.0
PYH1_k127_2614447_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1058.0
PYH1_k127_2614447_2 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 3.653e-212 670.0
PYH1_k127_2614447_3 HI0933-like protein - - - 1.435e-209 657.0
PYH1_k127_2614447_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 467.0
PYH1_k127_2614447_5 4Fe-4S binding domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 453.0
PYH1_k127_2614447_6 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 310.0
PYH1_k127_2614447_7 DMSO reductase K21309 - - 0.0000000000000000000000000000000000000000000000000000007561 197.0
PYH1_k127_2658353_0 PFAM Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 497.0
PYH1_k127_2658353_1 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 376.0
PYH1_k127_2658353_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001539 263.0
PYH1_k127_2658353_3 diol metabolic process K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000008525 171.0
PYH1_k127_2658353_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000006379 136.0
PYH1_k127_2658353_5 Putative prokaryotic signal transducing protein - - - 0.00000000000000000001061 96.0
PYH1_k127_2665722_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 459.0
PYH1_k127_2665722_1 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 267.0
PYH1_k127_2665722_2 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000001269 201.0
PYH1_k127_2706594_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1673.0
PYH1_k127_2706594_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1215.0
PYH1_k127_2706594_10 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 385.0
PYH1_k127_2706594_11 PFAM Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 355.0
PYH1_k127_2706594_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 344.0
PYH1_k127_2706594_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001037 219.0
PYH1_k127_2706594_14 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000001035 181.0
PYH1_k127_2706594_15 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000001804 131.0
PYH1_k127_2706594_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000008184 113.0
PYH1_k127_2706594_17 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000008664 69.0
PYH1_k127_2706594_18 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000299 60.0
PYH1_k127_2706594_19 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000269 55.0
PYH1_k127_2706594_2 dna topoisomerase III K03169 - 5.99.1.2 0.0 1110.0
PYH1_k127_2706594_3 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 2.216e-213 693.0
PYH1_k127_2706594_4 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 4.211e-206 653.0
PYH1_k127_2706594_5 PFAM TrkA-N domain protein K03499 - - 1.864e-194 620.0
PYH1_k127_2706594_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 573.0
PYH1_k127_2706594_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 432.0
PYH1_k127_2706594_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 436.0
PYH1_k127_2706594_9 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 414.0
PYH1_k127_2708334_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.41e-300 934.0
PYH1_k127_2708334_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 3.101e-296 918.0
PYH1_k127_2708334_10 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 415.0
PYH1_k127_2708334_11 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 368.0
PYH1_k127_2708334_12 Inner membrane protein involved in colicin E2 resistance K06143 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 367.0
PYH1_k127_2708334_13 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 335.0
PYH1_k127_2708334_14 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 325.0
PYH1_k127_2708334_15 Pfam:AmoA K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001087 276.0
PYH1_k127_2708334_16 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000976 236.0
PYH1_k127_2708334_17 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000006419 212.0
PYH1_k127_2708334_18 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000001934 207.0
PYH1_k127_2708334_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000008721 195.0
PYH1_k127_2708334_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 8.03e-277 857.0
PYH1_k127_2708334_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000004236 180.0
PYH1_k127_2708334_21 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000006601 184.0
PYH1_k127_2708334_22 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000003036 156.0
PYH1_k127_2708334_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000007629 143.0
PYH1_k127_2708334_25 Q COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000113 115.0
PYH1_k127_2708334_26 ATP synthase I chain K02116 - - 0.000000000000000003197 93.0
PYH1_k127_2708334_27 Histidine kinase - - - 0.0002561 51.0
PYH1_k127_2708334_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.824e-259 804.0
PYH1_k127_2708334_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.534e-199 630.0
PYH1_k127_2708334_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 565.0
PYH1_k127_2708334_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 477.0
PYH1_k127_2708334_7 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 459.0
PYH1_k127_2708334_8 Domain of unknown function (DUF4347) K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 469.0
PYH1_k127_2708334_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 428.0
PYH1_k127_2741432_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 1.647e-249 782.0
PYH1_k127_2741432_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.739e-197 623.0
PYH1_k127_2741432_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 441.0
PYH1_k127_2741432_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000003192 218.0
PYH1_k127_2741432_4 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000008425 194.0
PYH1_k127_275043_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 361.0
PYH1_k127_275043_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 291.0
PYH1_k127_275043_2 plastoquinol--plastocyanin reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001775 249.0
PYH1_k127_2752900_0 FAD binding domain K07077 - - 1.662e-222 705.0
PYH1_k127_2752900_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 1.437e-220 736.0
PYH1_k127_2752900_10 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 327.0
PYH1_k127_2752900_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001522 282.0
PYH1_k127_2752900_12 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000267 287.0
PYH1_k127_2752900_13 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004926 273.0
PYH1_k127_2752900_14 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005335 284.0
PYH1_k127_2752900_15 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002492 250.0
PYH1_k127_2752900_16 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000001684 205.0
PYH1_k127_2752900_17 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000001064 181.0
PYH1_k127_2752900_18 COGs COG4446 conserved - - - 0.00000000000000000000000000000000001996 141.0
PYH1_k127_2752900_19 Protein of unknown function (DUF2892) - - - 0.000000000000000000523 94.0
PYH1_k127_2752900_2 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 606.0
PYH1_k127_2752900_20 small protein containing a coiled-coil domain - - - 0.00000000000001117 76.0
PYH1_k127_2752900_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 513.0
PYH1_k127_2752900_4 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 457.0
PYH1_k127_2752900_5 Alpha beta hydrolase K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 411.0
PYH1_k127_2752900_6 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 409.0
PYH1_k127_2752900_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 398.0
PYH1_k127_2752900_8 7TM diverse intracellular signalling - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 389.0
PYH1_k127_2752900_9 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 402.0
PYH1_k127_2766348_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1241.0
PYH1_k127_2766348_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 460.0
PYH1_k127_2766348_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 419.0
PYH1_k127_2766348_3 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 382.0
PYH1_k127_2766348_4 Protein of unknown function (DUF3302) - - - 0.00000000000000000000000000000000000000006897 155.0
PYH1_k127_2766348_5 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000005558 106.0
PYH1_k127_2771658_0 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 459.0
PYH1_k127_2771658_1 PFAM HNH endonuclease - - - 0.000001436 56.0
PYH1_k127_2806360_0 pilus assembly protein tip-associated adhesin K02674 - - 3.697e-295 971.0
PYH1_k127_2806360_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000004679 226.0
PYH1_k127_2806360_2 General secretion pathway protein K02459,K02672,K02680 - - 0.000000000000000000000000000000000000000000000000003767 203.0
PYH1_k127_2806360_3 Type II transport protein GspH K08084 - - 0.0000000000000000000000000000000000000001416 165.0
PYH1_k127_2806360_4 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000001716 146.0
PYH1_k127_2806360_5 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000001939 123.0
PYH1_k127_2806360_6 Pilus assembly protein PilX - - - 0.000000000000000000000000004008 128.0
PYH1_k127_2806360_7 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000001107 110.0
PYH1_k127_2806360_8 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.000008581 51.0
PYH1_k127_2820987_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 489.0
PYH1_k127_2820987_1 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 422.0
PYH1_k127_2820987_10 NfeD-like C-terminal, partner-binding - - - 0.00000000000005109 78.0
PYH1_k127_2820987_11 PFAM major facilitator superfamily MFS_1 - - - 0.0000001224 64.0
PYH1_k127_2820987_12 DNA-sulfur modification-associated - - - 0.0000004347 62.0
PYH1_k127_2820987_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 414.0
PYH1_k127_2820987_3 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 399.0
PYH1_k127_2820987_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007094 259.0
PYH1_k127_2820987_5 2-keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000002837 226.0
PYH1_k127_2820987_6 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000001048 221.0
PYH1_k127_2820987_7 luciferase - - - 0.0000000000000000000000000000000000000006057 166.0
PYH1_k127_2820987_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000007799 134.0
PYH1_k127_2820987_9 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000003974 73.0
PYH1_k127_2892970_0 Secretin and TonB N terminus short domain K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 580.0
PYH1_k127_2892970_1 carbon utilization - - - 0.00000000000000000001599 100.0
PYH1_k127_2892970_2 - - - - 0.0000000000007358 74.0
PYH1_k127_2892970_3 - - - - 0.000000000002119 78.0
PYH1_k127_2898879_0 Sulfatase K01130,K01138 - 3.1.6.1 0.0 1379.0
PYH1_k127_2898879_1 Domain of Unknown Function (DUF748) - - - 6.641e-233 760.0
PYH1_k127_2898879_10 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 382.0
PYH1_k127_2898879_11 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 301.0
PYH1_k127_2898879_12 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000000005762 197.0
PYH1_k127_2898879_13 - - - - 0.0000000000000000005914 94.0
PYH1_k127_2898879_2 Sulfatase - - - 2.156e-222 698.0
PYH1_k127_2898879_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 1.352e-215 680.0
PYH1_k127_2898879_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 434.0
PYH1_k127_2898879_5 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 426.0
PYH1_k127_2898879_6 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 406.0
PYH1_k127_2898879_7 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 403.0
PYH1_k127_2898879_8 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 382.0
PYH1_k127_2898879_9 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 364.0
PYH1_k127_2906928_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1144.0
PYH1_k127_2906928_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.399e-237 745.0
PYH1_k127_2906928_10 - - - - 0.0003577 53.0
PYH1_k127_2906928_2 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 1.099e-201 639.0
PYH1_k127_2906928_3 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 610.0
PYH1_k127_2906928_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 371.0
PYH1_k127_2906928_5 alcohol dehydrogenase K00001 GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004022,GO:0004552,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0007610,GO:0007611,GO:0007612,GO:0007632,GO:0008150,GO:0008152,GO:0008306,GO:0008542,GO:0009314,GO:0009416,GO:0009628,GO:0016491,GO:0016614,GO:0016616,GO:0016651,GO:0016657,GO:0019222,GO:0031323,GO:0031399,GO:0032268,GO:0032501,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051171,GO:0051246,GO:0051903,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080007,GO:0080090,GO:0080164,GO:1901615,GO:2000169,GO:2000377 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 355.0
PYH1_k127_2906928_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
PYH1_k127_2906928_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000001416 130.0
PYH1_k127_2906928_8 helix_turn_helix, mercury resistance - - - 0.00000000000000000000001911 102.0
PYH1_k127_2906928_9 cytochrome - - - 0.000000000000006327 82.0
PYH1_k127_2920995_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 330.0
PYH1_k127_2920995_1 Protein involved in outer membrane biogenesis - - - 0.000000000000002021 89.0
PYH1_k127_2948690_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1442.0
PYH1_k127_2948690_1 Ami_2 K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000008059 254.0
PYH1_k127_2948690_2 Sigma-54 interaction domain protein K07713 - - 0.00007828 46.0
PYH1_k127_2968146_0 Insecticidal toxin complex protein TcaC - - - 3.355e-228 751.0
PYH1_k127_2968146_1 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 497.0
PYH1_k127_2968146_2 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 385.0
PYH1_k127_2968146_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 341.0
PYH1_k127_2968146_4 TIGRFAM RHS repeat-associated core domain - - - 0.000000000000000000000000000000000000001146 164.0
PYH1_k127_2968146_5 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000000000000000007869 141.0
PYH1_k127_2968146_6 - - - - 0.00000000000000000000001749 106.0
PYH1_k127_2968146_7 Domain of unknown function (DUF4124) - - - 0.00000000000000000003389 98.0
PYH1_k127_2968146_8 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000001758 87.0
PYH1_k127_3009423_0 rieske 2fe-2s K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 506.0
PYH1_k127_3009423_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 392.0
PYH1_k127_3009423_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 314.0
PYH1_k127_3009423_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 272.0
PYH1_k127_3009423_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000007054 151.0
PYH1_k127_3009423_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000003199 90.0
PYH1_k127_3009423_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000128 74.0
PYH1_k127_3023443_0 ribonuclease, Rne Rng family K08301 - - 6.832e-226 717.0
PYH1_k127_3023443_1 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 598.0
PYH1_k127_3023443_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
PYH1_k127_3023443_3 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 313.0
PYH1_k127_3023443_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 312.0
PYH1_k127_3023443_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000007949 222.0
PYH1_k127_3023443_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000001148 168.0
PYH1_k127_3023443_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000006323 81.0
PYH1_k127_3057401_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 461.0
PYH1_k127_3057401_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 320.0
PYH1_k127_3057401_2 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000005275 170.0
PYH1_k127_3057401_3 Protein of unknown function (DUF3467) - - - 0.000000000000111 74.0
PYH1_k127_3058695_0 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 490.0
PYH1_k127_3058695_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
PYH1_k127_3058695_2 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000001245 98.0
PYH1_k127_3066687_0 Methyl-accepting chemotaxis protein K02660 - - 2.44e-220 705.0
PYH1_k127_3066687_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 321.0
PYH1_k127_3066687_2 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000009253 222.0
PYH1_k127_3066687_3 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000004522 181.0
PYH1_k127_3066687_4 Chemotaxis signal transduction protein K02659 - - 0.00000000000000000000000000000000000004709 150.0
PYH1_k127_3066687_5 Rubredoxin - - - 0.0000000000000000000000000000005591 123.0
PYH1_k127_3066687_6 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0000000000000000000000000000741 121.0
PYH1_k127_3067249_0 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 586.0
PYH1_k127_3067249_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 524.0
PYH1_k127_3067249_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 467.0
PYH1_k127_3067249_3 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000000008977 163.0
PYH1_k127_3067249_4 NlpC/P60 family K13695,K19303 - - 0.00000000000000000000000000000000000003135 148.0
PYH1_k127_3067249_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000009174 78.0
PYH1_k127_3068360_0 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 597.0
PYH1_k127_3068360_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 424.0
PYH1_k127_3068360_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 353.0
PYH1_k127_3068360_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005396 252.0
PYH1_k127_3068360_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000009822 181.0
PYH1_k127_3068360_5 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000989 176.0
PYH1_k127_3068360_6 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000004824 146.0
PYH1_k127_3068360_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000001865 133.0
PYH1_k127_3068360_8 Sel1-like repeats. - - - 0.00001089 53.0
PYH1_k127_3168293_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.02e-206 659.0
PYH1_k127_3168293_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 2.962e-205 653.0
PYH1_k127_3168293_10 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000142 86.0
PYH1_k127_3168293_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 606.0
PYH1_k127_3168293_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 537.0
PYH1_k127_3168293_4 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 497.0
PYH1_k127_3168293_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 400.0
PYH1_k127_3168293_6 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 305.0
PYH1_k127_3168293_7 synthesis repressor, PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000001156 250.0
PYH1_k127_3168293_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001133 225.0
PYH1_k127_3168293_9 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000001438 141.0
PYH1_k127_3175293_0 Phosphoesterase family - - - 1.786e-201 642.0
PYH1_k127_3175293_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 377.0
PYH1_k127_3175293_2 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000001179 216.0
PYH1_k127_3175293_3 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000006759 197.0
PYH1_k127_3175293_4 Protein chain release factor B K15034 - - 0.000000000000000000000000000000000000000005071 158.0
PYH1_k127_3175293_5 - - - - 0.0000000000000000000187 97.0
PYH1_k127_3217518_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 600.0
PYH1_k127_3217518_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 539.0
PYH1_k127_3217518_2 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 497.0
PYH1_k127_3217518_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 367.0
PYH1_k127_3217518_4 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 349.0
PYH1_k127_3217518_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000003702 229.0
PYH1_k127_3217518_6 Porin subfamily - - - 0.00000000000000000000000000000000000001305 161.0
PYH1_k127_3217518_7 - - - - 0.00000001309 68.0
PYH1_k127_3217518_8 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000004734 52.0
PYH1_k127_3230435_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 380.0
PYH1_k127_3230435_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 390.0
PYH1_k127_3230435_10 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000004005 177.0
PYH1_k127_3230435_11 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.0000000000000000000000000000000253 134.0
PYH1_k127_3230435_12 FeS assembly protein IscX - - - 0.0000000000000000000002701 111.0
PYH1_k127_3230435_13 BolA-like protein K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000002783 100.0
PYH1_k127_3230435_14 Ankyrin repeat - - - 0.0000000000003719 82.0
PYH1_k127_3230435_15 - - - - 0.000007208 58.0
PYH1_k127_3230435_2 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 261.0
PYH1_k127_3230435_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000001649 244.0
PYH1_k127_3230435_4 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000002404 236.0
PYH1_k127_3230435_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000008253 225.0
PYH1_k127_3230435_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
PYH1_k127_3230435_7 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000003524 218.0
PYH1_k127_3230435_8 - - - - 0.00000000000000000000000000000000000000000000000000000001796 216.0
PYH1_k127_3230435_9 Alanine acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000001083 196.0
PYH1_k127_3233793_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 457.0
PYH1_k127_3233793_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 410.0
PYH1_k127_3233793_2 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000183 297.0
PYH1_k127_3257981_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 4.036e-240 751.0
PYH1_k127_3257981_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000004803 242.0
PYH1_k127_3257981_2 Stress-induced protein - - - 0.00000000000000000000000000000000000000001098 156.0
PYH1_k127_3257981_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000002457 106.0
PYH1_k127_3285932_0 Heat shock 70 kDa protein K04043 - - 0.0 1053.0
PYH1_k127_3285932_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 581.0
PYH1_k127_3285932_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 454.0
PYH1_k127_3285932_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 354.0
PYH1_k127_3285932_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 311.0
PYH1_k127_3285932_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006967 286.0
PYH1_k127_3285932_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000003796 154.0
PYH1_k127_3285932_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000001644 138.0
PYH1_k127_3285932_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000006002 65.0
PYH1_k127_3332436_0 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 324.0
PYH1_k127_3332436_1 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000001096 196.0
PYH1_k127_3332436_2 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000002118 192.0
PYH1_k127_3332436_3 Alpha/beta hydrolase family - - - 0.000000000000000000198 100.0
PYH1_k127_3357302_0 FAD dependent oxidoreductase - - - 2.314e-238 748.0
PYH1_k127_3357302_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 577.0
PYH1_k127_3357302_2 PFAM MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 554.0
PYH1_k127_3357302_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 389.0
PYH1_k127_3357302_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 329.0
PYH1_k127_3361370_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 3.941e-221 706.0
PYH1_k127_3361370_1 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 338.0
PYH1_k127_3361370_2 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000105 261.0
PYH1_k127_3361370_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000001186 219.0
PYH1_k127_3361370_4 PFAM fumarate reductase succinate dehydrogenase flavoprotein K16885 - - 0.0000000000000000000000000000000000000000000000000006176 188.0
PYH1_k127_3361370_5 - - - - 0.0000000000000000000000003532 109.0
PYH1_k127_3370594_0 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 436.0
PYH1_k127_3370594_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
PYH1_k127_3370594_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000000003448 173.0
PYH1_k127_3370594_3 TIGRFAM MJ0042 family finger-like protein - - - 0.000000000000000000000000000000000007821 140.0
PYH1_k127_3370594_4 Mg chelatase subunit ChlI K07391 - - 0.0000000000000000000001426 98.0
PYH1_k127_3377298_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1104.0
PYH1_k127_3377298_1 Protein of unknown function (DUF3141) - - - 0.0 1034.0
PYH1_k127_3377298_10 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 439.0
PYH1_k127_3377298_11 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 436.0
PYH1_k127_3377298_12 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 355.0
PYH1_k127_3377298_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 357.0
PYH1_k127_3377298_14 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 350.0
PYH1_k127_3377298_15 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 329.0
PYH1_k127_3377298_16 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 317.0
PYH1_k127_3377298_17 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 295.0
PYH1_k127_3377298_18 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005951 293.0
PYH1_k127_3377298_19 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002731 267.0
PYH1_k127_3377298_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.751e-315 978.0
PYH1_k127_3377298_20 response regulator K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007773 271.0
PYH1_k127_3377298_21 sulfur relay protein TusD DsrE K07235 - - 0.0000000000000000000000000000000000000000000000000000000000006119 211.0
PYH1_k127_3377298_22 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000000005565 199.0
PYH1_k127_3377298_23 Sulfur relay protein TusC DsrF K07236 - - 0.0000000000000000000000000000000000000000000000000008196 190.0
PYH1_k127_3377298_24 - - - - 0.000000000000000000000000000000000000000000000000009887 193.0
PYH1_k127_3377298_25 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000001975 177.0
PYH1_k127_3377298_26 DsrC like protein K11179 - - 0.000000000000000000000000000000000000007896 159.0
PYH1_k127_3377298_27 lipid catabolic process - - - 0.00000000000000000000000000000000001919 152.0
PYH1_k127_3377298_28 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000004127 144.0
PYH1_k127_3377298_29 DsrH like protein K07237 - - 0.000000000000000000000000000000001948 138.0
PYH1_k127_3377298_3 Fe-S oxidoreductase K21834 - - 4.262e-251 784.0
PYH1_k127_3377298_30 Pfam Family of - - - 0.0000000000000000000000000000008676 141.0
PYH1_k127_3377298_31 Cas6 Crispr - - - 0.000000000000000000000000000004623 130.0
PYH1_k127_3377298_32 - - - - 0.000000000000000000000000006934 110.0
PYH1_k127_3377298_33 - - - - 0.00000000000000000000000001039 116.0
PYH1_k127_3377298_34 - - - - 0.00000000000000000000000003465 123.0
PYH1_k127_3377298_35 Peptidase M48 - - - 0.0000000000000000000000002679 109.0
PYH1_k127_3377298_36 - - - - 0.0000000000000000008601 92.0
PYH1_k127_3377298_37 belongs to the aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 0.0000000001344 63.0
PYH1_k127_3377298_38 RNA recognition motif - - - 0.0002229 48.0
PYH1_k127_3377298_4 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.775e-218 688.0
PYH1_k127_3377298_5 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.347e-212 665.0
PYH1_k127_3377298_6 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 5.565e-204 672.0
PYH1_k127_3377298_7 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 572.0
PYH1_k127_3377298_8 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 537.0
PYH1_k127_3377298_9 PFAM phosphate acetyl butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 458.0
PYH1_k127_3395037_0 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 473.0
PYH1_k127_3395037_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 463.0
PYH1_k127_3395037_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000003549 190.0
PYH1_k127_3395037_3 L-lactate dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.00000000002265 64.0
PYH1_k127_3404079_0 Cation transporting ATPase, C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 398.0
PYH1_k127_3404079_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 324.0
PYH1_k127_3404079_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001335 239.0
PYH1_k127_3404079_3 Pfam Response regulator receiver - - - 0.0000000000001682 75.0
PYH1_k127_3433942_0 polyphosphate kinase - - - 4.858e-235 735.0
PYH1_k127_3456145_0 Tripartite tricarboxylate transporter TctA family - - - 8.666e-226 708.0
PYH1_k127_3456145_1 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000726 110.0
PYH1_k127_3466257_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 489.0
PYH1_k127_3466257_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 338.0
PYH1_k127_3466257_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000005343 105.0
PYH1_k127_3474846_0 PFAM carboxyl transferase K01615 - 4.1.1.70 4.214e-295 915.0
PYH1_k127_3474846_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 540.0
PYH1_k127_3474846_2 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 544.0
PYH1_k127_3474846_3 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 305.0
PYH1_k127_3474846_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000463 177.0
PYH1_k127_3474846_5 Cupin domain - - - 0.0000000000000000000000000000000000000216 151.0
PYH1_k127_3474846_6 GYD domain - - - 0.000000000000000000000000000005829 121.0
PYH1_k127_3474846_7 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.0000000000000002671 78.0
PYH1_k127_3474846_8 Sulfite exporter TauE/SafE - - - 0.00000000000001258 78.0
PYH1_k127_3494480_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 601.0
PYH1_k127_3494480_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 326.0
PYH1_k127_3495185_0 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 379.0
PYH1_k127_3495185_1 FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 357.0
PYH1_k127_3495185_2 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 324.0
PYH1_k127_3495185_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 314.0
PYH1_k127_3495185_4 Hsp33 protein K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008895 261.0
PYH1_k127_3495185_5 Protein of unknown function (DUF3467) - - - 0.0000000000007559 69.0
PYH1_k127_3504106_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000005306 225.0
PYH1_k127_3504106_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000008957 221.0
PYH1_k127_3504106_2 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000006076 218.0
PYH1_k127_3504106_3 - - - - 0.00000000000000000000000000006109 124.0
PYH1_k127_3536722_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 558.0
PYH1_k127_3536722_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 562.0
PYH1_k127_3536722_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 467.0
PYH1_k127_3536722_3 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 351.0
PYH1_k127_3536722_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008188 277.0
PYH1_k127_3536722_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002643 243.0
PYH1_k127_3536722_6 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000003879 203.0
PYH1_k127_3536722_7 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000001476 57.0
PYH1_k127_3552654_0 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 2.946e-314 1007.0
PYH1_k127_3552654_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.29e-264 823.0
PYH1_k127_3552654_2 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 1.798e-238 747.0
PYH1_k127_3552654_3 AMP-binding enzyme K12508 - 6.2.1.34 7.108e-220 702.0
PYH1_k127_3552654_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 365.0
PYH1_k127_3552654_5 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 359.0
PYH1_k127_3552654_6 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000002141 187.0
PYH1_k127_3552654_7 Transcriptional regulator - - - 0.0000000000000000000000000001411 119.0
PYH1_k127_3553796_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 559.0
PYH1_k127_3553796_1 Lipase (class 2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 533.0
PYH1_k127_3553796_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000003476 227.0
PYH1_k127_3553796_3 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000002322 180.0
PYH1_k127_3553796_4 - - - - 0.00000000000000000000000117 109.0
PYH1_k127_3553796_5 Mitochondrial biogenesis AIM24 - - - 0.000002829 53.0
PYH1_k127_3573276_0 Belongs to the LDH2 MDH2 oxidoreductase family K00073,K13574 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 428.0
PYH1_k127_3573276_1 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001057 259.0
PYH1_k127_3573276_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000001131 66.0
PYH1_k127_3598218_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.266e-285 887.0
PYH1_k127_3598218_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 558.0
PYH1_k127_3598218_2 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 507.0
PYH1_k127_3598218_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 429.0
PYH1_k127_3598218_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000001204 179.0
PYH1_k127_3598218_5 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000005745 138.0
PYH1_k127_3608398_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1177.0
PYH1_k127_3608398_1 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000005935 208.0
PYH1_k127_364729_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1352.0
PYH1_k127_364729_1 Molecular chaperone. Has ATPase activity K04079 - - 1.926e-287 894.0
PYH1_k127_364729_10 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 403.0
PYH1_k127_364729_11 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 391.0
PYH1_k127_364729_12 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 398.0
PYH1_k127_364729_13 Trypsin K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
PYH1_k127_364729_14 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 377.0
PYH1_k127_364729_15 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 343.0
PYH1_k127_364729_16 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 334.0
PYH1_k127_364729_17 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
PYH1_k127_364729_18 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001163 284.0
PYH1_k127_364729_19 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002836 255.0
PYH1_k127_364729_2 Methylmalonyl-CoA mutase K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 6.602e-243 780.0
PYH1_k127_364729_20 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000001175 246.0
PYH1_k127_364729_21 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000003013 220.0
PYH1_k127_364729_22 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000003165 217.0
PYH1_k127_364729_23 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000004311 217.0
PYH1_k127_364729_24 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000004623 215.0
PYH1_k127_364729_25 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000006867 194.0
PYH1_k127_364729_26 TonB C terminal K03646 - - 0.000000000000000000000000000000000000000000000003448 187.0
PYH1_k127_364729_27 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000005472 193.0
PYH1_k127_364729_28 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000006227 180.0
PYH1_k127_364729_29 response to cobalt ion - - - 0.0000000000000000000000000000000000000000000002585 174.0
PYH1_k127_364729_3 Bacterial protein of unknown function (DUF853) K06915 - - 5.581e-227 712.0
PYH1_k127_364729_30 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.00000000000000000000000000000000000000000005915 170.0
PYH1_k127_364729_31 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000004671 151.0
PYH1_k127_364729_32 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000003861 144.0
PYH1_k127_364729_33 TspO MBR family protein K05770 - - 0.0000000000000000000000000000000002671 142.0
PYH1_k127_364729_34 Acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000001582 137.0
PYH1_k127_364729_35 Protein of unknown function (DUF805) - - - 0.00000000000000000000000000007381 120.0
PYH1_k127_364729_36 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000008063 117.0
PYH1_k127_364729_37 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000003577 128.0
PYH1_k127_364729_38 - - - - 0.00000000000000000000000003212 109.0
PYH1_k127_364729_39 Belongs to the P(II) protein family - - - 0.000000000000001986 89.0
PYH1_k127_364729_4 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 609.0
PYH1_k127_364729_40 Transglycosylase associated protein - - - 0.0000000009938 63.0
PYH1_k127_364729_41 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000003611 59.0
PYH1_k127_364729_42 - - - - 0.0001777 46.0
PYH1_k127_364729_5 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 571.0
PYH1_k127_364729_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 541.0
PYH1_k127_364729_7 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 501.0
PYH1_k127_364729_8 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 508.0
PYH1_k127_364729_9 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 471.0
PYH1_k127_3669739_0 amino acid - - - 1.516e-278 879.0
PYH1_k127_3669739_1 type I secretion membrane fusion protein, HlyD family K11003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 302.0
PYH1_k127_3669739_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000002054 265.0
PYH1_k127_3669739_3 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000000001616 190.0
PYH1_k127_3669739_4 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000006233 180.0
PYH1_k127_3669739_5 SapC - - - 0.000000000000000000000000000000000000000004171 164.0
PYH1_k127_3669739_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000001902 119.0
PYH1_k127_3688048_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 435.0
PYH1_k127_3688048_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 352.0
PYH1_k127_3688048_2 Competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000004447 158.0
PYH1_k127_3688048_3 Dodecin K09165 - - 0.000000000000000000005875 96.0
PYH1_k127_3689863_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1219.0
PYH1_k127_3689863_1 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000004809 184.0
PYH1_k127_371903_0 Malic enzyme K00029 - 1.1.1.40 0.0 1056.0
PYH1_k127_371903_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 461.0
PYH1_k127_371903_2 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 437.0
PYH1_k127_371903_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 425.0
PYH1_k127_371903_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 400.0
PYH1_k127_371903_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001315 233.0
PYH1_k127_371903_6 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000005452 183.0
PYH1_k127_371903_7 SapC - - - 0.00000000000000000000000000000000000000005398 160.0
PYH1_k127_371903_8 - - - - 0.00000000000000000003166 92.0
PYH1_k127_371903_9 - - - - 0.0000000000000001313 81.0
PYH1_k127_372251_0 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.025e-227 727.0
PYH1_k127_372251_1 STAS domain K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 577.0
PYH1_k127_372251_2 FAD binding domain K11472 - - 0.0000000000000000000000000000004442 134.0
PYH1_k127_376309_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 592.0
PYH1_k127_376309_1 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 535.0
PYH1_k127_376309_2 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 420.0
PYH1_k127_376309_3 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000006118 228.0
PYH1_k127_376309_4 NAD dependent epimerase/dehydratase family K00046 - 1.1.1.69 0.0000000000000000000000000000000000005607 141.0
PYH1_k127_376309_5 Histidine kinase-like ATPase domain - - - 0.000000000000000000000001149 113.0
PYH1_k127_3767986_0 Aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 610.0
PYH1_k127_3767986_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 593.0
PYH1_k127_3767986_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000001089 74.0
PYH1_k127_3780487_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 602.0
PYH1_k127_3780487_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000002039 249.0
PYH1_k127_3796309_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 467.0
PYH1_k127_3796309_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 476.0
PYH1_k127_3796309_2 KR domain K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 342.0
PYH1_k127_3796309_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 269.0
PYH1_k127_3796309_4 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000002896 232.0
PYH1_k127_3796309_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000001657 149.0
PYH1_k127_3796309_6 Hemerythrin HHE cation binding domain - - - 0.0001945 46.0
PYH1_k127_3798607_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1366.0
PYH1_k127_3798607_1 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 485.0
PYH1_k127_3798607_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003591 274.0
PYH1_k127_3798607_3 Protein of unknown function (DUF2877) - - - 0.000000000000000000245 91.0
PYH1_k127_3798607_4 TIGRFAM DnaA regulatory inactivator Hda K10763 - - 0.00000000000168 78.0
PYH1_k127_3860519_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 533.0
PYH1_k127_3860519_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000005164 171.0
PYH1_k127_3860519_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000005313 121.0
PYH1_k127_3862897_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1192.0
PYH1_k127_3862897_1 Hydantoinase/oxoprolinase - - - 9.002e-277 876.0
PYH1_k127_3862897_10 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000004935 183.0
PYH1_k127_3862897_11 - - - - 0.000000000000000000000003229 111.0
PYH1_k127_3862897_12 LTXXQ motif family protein - - - 0.000000000000000000003969 98.0
PYH1_k127_3862897_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 4.491e-251 790.0
PYH1_k127_3862897_3 COG1180 Pyruvate-formate lyase-activating enzyme - - - 5.033e-233 728.0
PYH1_k127_3862897_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 571.0
PYH1_k127_3862897_5 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 347.0
PYH1_k127_3862897_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 354.0
PYH1_k127_3862897_7 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 306.0
PYH1_k127_3862897_8 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 298.0
PYH1_k127_3862897_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003794 287.0
PYH1_k127_3865093_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 3.695e-265 847.0
PYH1_k127_3865093_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.527e-241 750.0
PYH1_k127_3865093_10 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 386.0
PYH1_k127_3865093_11 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 397.0
PYH1_k127_3865093_12 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 397.0
PYH1_k127_3865093_13 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 385.0
PYH1_k127_3865093_14 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 359.0
PYH1_k127_3865093_15 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 346.0
PYH1_k127_3865093_16 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 330.0
PYH1_k127_3865093_17 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 327.0
PYH1_k127_3865093_18 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 312.0
PYH1_k127_3865093_19 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003031 280.0
PYH1_k127_3865093_2 ABC transporter - - - 6.153e-241 755.0
PYH1_k127_3865093_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002182 289.0
PYH1_k127_3865093_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001124 270.0
PYH1_k127_3865093_22 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001859 259.0
PYH1_k127_3865093_23 hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006778 247.0
PYH1_k127_3865093_24 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000003564 246.0
PYH1_k127_3865093_25 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
PYH1_k127_3865093_26 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000006689 226.0
PYH1_k127_3865093_27 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000005621 215.0
PYH1_k127_3865093_28 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000002346 186.0
PYH1_k127_3865093_29 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000003205 187.0
PYH1_k127_3865093_3 BT1 family - - - 2.833e-231 729.0
PYH1_k127_3865093_30 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000004814 168.0
PYH1_k127_3865093_31 FecR protein - - - 0.00000000000000000000000000000000000000000103 171.0
PYH1_k127_3865093_32 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000001785 160.0
PYH1_k127_3865093_33 Redoxin - - - 0.0000000000000000000000000000000000000001737 156.0
PYH1_k127_3865093_34 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000001144 124.0
PYH1_k127_3865093_35 - - - - 0.000000000000000000001012 99.0
PYH1_k127_3865093_36 - - - - 0.0000000107 62.0
PYH1_k127_3865093_4 Glucose inhibited division protein A - - - 3.126e-214 694.0
PYH1_k127_3865093_5 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 2.671e-209 679.0
PYH1_k127_3865093_6 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 3.939e-195 621.0
PYH1_k127_3865093_7 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 421.0
PYH1_k127_3865093_8 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 423.0
PYH1_k127_3865093_9 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 391.0
PYH1_k127_3971737_0 AMP-binding enzyme C-terminal domain K00666 - - 2.459e-271 842.0
PYH1_k127_3971737_1 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 383.0
PYH1_k127_3971737_2 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 398.0
PYH1_k127_3971737_3 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 373.0
PYH1_k127_3971737_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 321.0
PYH1_k127_3971737_5 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 286.0
PYH1_k127_3971737_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004162 281.0
PYH1_k127_3971737_7 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002638 262.0
PYH1_k127_3971737_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003733 260.0
PYH1_k127_3971737_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000006185 234.0
PYH1_k127_3972762_0 ABC transporter K15738 - - 2.943e-216 684.0
PYH1_k127_3972762_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 403.0
PYH1_k127_3972762_2 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 299.0
PYH1_k127_3972762_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005876 232.0
PYH1_k127_3972762_4 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000009268 87.0
PYH1_k127_3985458_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.872e-255 797.0
PYH1_k127_3985458_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 287.0
PYH1_k127_3985458_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 259.0
PYH1_k127_3985458_3 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002889 248.0
PYH1_k127_3985458_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000379 123.0
PYH1_k127_3985458_5 CNP1-like family - - - 0.00000000000000000000000000006402 128.0
PYH1_k127_4003832_0 - - - - 7.606e-234 760.0
PYH1_k127_4003832_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 516.0
PYH1_k127_4003832_10 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000001875 246.0
PYH1_k127_4003832_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000001944 186.0
PYH1_k127_4003832_12 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000629 184.0
PYH1_k127_4003832_13 MAPEG family - - - 0.000000000000000000000000000000000000000001884 160.0
PYH1_k127_4003832_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 486.0
PYH1_k127_4003832_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 385.0
PYH1_k127_4003832_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 400.0
PYH1_k127_4003832_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 355.0
PYH1_k127_4003832_6 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
PYH1_k127_4003832_7 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 293.0
PYH1_k127_4003832_8 Beta-lactamase K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001702 283.0
PYH1_k127_4003832_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001341 282.0
PYH1_k127_4013987_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1307.0
PYH1_k127_4013987_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1071.0
PYH1_k127_4013987_2 AMP-binding enzyme C-terminal domain - - - 2.573e-218 690.0
PYH1_k127_4013987_3 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 572.0
PYH1_k127_4013987_4 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000005048 153.0
PYH1_k127_4013987_5 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000002458 128.0
PYH1_k127_4013987_6 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000000000000001645 132.0
PYH1_k127_4013987_7 - - - - 0.0000000000003078 78.0
PYH1_k127_4062928_0 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 413.0
PYH1_k127_4062928_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 301.0
PYH1_k127_4062928_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 292.0
PYH1_k127_4062928_3 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000003857 193.0
PYH1_k127_4062928_4 Cytochrome c - - - 0.000000000000000000000000000000001541 130.0
PYH1_k127_4062928_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000003986 111.0
PYH1_k127_4062928_6 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000008553 114.0
PYH1_k127_4079094_0 GTP-binding protein TypA K06207 - - 6.052e-304 941.0
PYH1_k127_4079094_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 535.0
PYH1_k127_4079094_2 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 446.0
PYH1_k127_4079094_3 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 411.0
PYH1_k127_4079094_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 326.0
PYH1_k127_4079094_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 314.0
PYH1_k127_4079094_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0008150,GO:0040007 5.4.99.18 0.00000000000007317 83.0
PYH1_k127_408972_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 495.0
PYH1_k127_408972_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 463.0
PYH1_k127_408972_2 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 312.0
PYH1_k127_408972_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 307.0
PYH1_k127_408972_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 305.0
PYH1_k127_408972_5 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000006668 245.0
PYH1_k127_408972_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000001178 227.0
PYH1_k127_4118004_0 Cytochrome D1 heme domain K19345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 383.0
PYH1_k127_4118004_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000064 171.0
PYH1_k127_4118004_2 Cytochrome C oxidase, cbb3-type, subunit III K19344 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000001514 106.0
PYH1_k127_4120475_0 Pfam:DUF1446 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 574.0
PYH1_k127_4120475_1 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000002358 237.0
PYH1_k127_4170611_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.985e-200 644.0
PYH1_k127_4170611_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 508.0
PYH1_k127_4170611_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000123 264.0
PYH1_k127_4170611_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000001313 222.0
PYH1_k127_4170611_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000273 164.0
PYH1_k127_4191306_0 MMPL family - - - 0.0 1310.0
PYH1_k127_4191306_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.4e-226 728.0
PYH1_k127_4191306_10 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000009076 69.0
PYH1_k127_4191306_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.715e-196 627.0
PYH1_k127_4191306_3 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 441.0
PYH1_k127_4191306_4 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 347.0
PYH1_k127_4191306_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002176 271.0
PYH1_k127_4191306_6 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000003305 263.0
PYH1_k127_4191306_7 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000004701 171.0
PYH1_k127_4191306_8 Invasion gene expression up-regulator SirB - - - 0.0000000000000000000000000000004021 127.0
PYH1_k127_4191306_9 Universal stress protein family - - - 0.0000000000000000000000000009212 122.0
PYH1_k127_4207425_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 473.0
PYH1_k127_4207425_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 361.0
PYH1_k127_4207425_2 Belongs to the P(II) protein family K04752 - - 0.0000000002618 64.0
PYH1_k127_4221685_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 326.0
PYH1_k127_4221685_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000005515 233.0
PYH1_k127_4221685_2 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000003576 177.0
PYH1_k127_4221685_3 MarC family integral membrane protein K05595 - - 0.00000000005294 68.0
PYH1_k127_4248981_0 Arylsulfatase K01130,K01138 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 478.0
PYH1_k127_4248981_1 Allophanate hydrolase K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 426.0
PYH1_k127_4248981_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 342.0
PYH1_k127_4248981_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005904 261.0
PYH1_k127_4248981_4 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.00000000000000000000000000000000000000000000000001723 186.0
PYH1_k127_4248981_5 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000852 175.0
PYH1_k127_4248981_6 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.0000000000000000000000000000000000007418 149.0
PYH1_k127_4248981_7 response to hydrogen peroxide K08985 - - 0.000000000000000006864 96.0
PYH1_k127_4248981_8 methyltransferase activity - - - 0.0003092 49.0
PYH1_k127_4261319_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 453.0
PYH1_k127_4261319_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 361.0
PYH1_k127_4261319_2 Putative serine dehydratase domain - - - 0.000000000000000000000000000000005588 145.0
PYH1_k127_4261319_3 - - - - 0.00000000000000000000398 108.0
PYH1_k127_4268247_0 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 589.0
PYH1_k127_4268247_1 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 349.0
PYH1_k127_4268247_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 332.0
PYH1_k127_4268247_3 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000122 188.0
PYH1_k127_4310293_0 SNARE associated Golgi protein - - - 0.0 1024.0
PYH1_k127_4310293_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 545.0
PYH1_k127_4310293_2 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 468.0
PYH1_k127_4310293_3 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 404.0
PYH1_k127_4310293_4 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004015 301.0
PYH1_k127_4310293_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000001852 177.0
PYH1_k127_4310293_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000001605 137.0
PYH1_k127_4326734_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.023e-255 796.0
PYH1_k127_4326734_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 602.0
PYH1_k127_4326734_2 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 415.0
PYH1_k127_4326734_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 366.0
PYH1_k127_4326734_4 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 350.0
PYH1_k127_4326734_5 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 339.0
PYH1_k127_4326734_6 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 287.0
PYH1_k127_4326734_7 CoA binding domain - - - 0.000000000000000000000000000000000000000000001843 169.0
PYH1_k127_4326734_8 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000007372 160.0
PYH1_k127_4329772_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1043.0
PYH1_k127_4382286_0 extracellular solute-binding protein - - - 2.528e-293 930.0
PYH1_k127_4382286_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 537.0
PYH1_k127_4382286_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 513.0
PYH1_k127_4382286_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 381.0
PYH1_k127_4382286_4 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 378.0
PYH1_k127_4382286_5 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000002929 60.0
PYH1_k127_4411764_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1591.0
PYH1_k127_4411764_1 transcriptional Regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001402 253.0
PYH1_k127_4452835_0 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 299.0
PYH1_k127_4452835_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002327 301.0
PYH1_k127_4452835_2 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000003596 94.0
PYH1_k127_4452835_3 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000002197 68.0
PYH1_k127_4462463_0 Exopolysaccharide biosynthesis protein YbjH - - - 1.977e-215 701.0
PYH1_k127_4462463_1 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 599.0
PYH1_k127_4462463_2 fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 521.0
PYH1_k127_4462463_3 addiction module toxin, RelE StbE family K19157 - - 0.000000000000000443 83.0
PYH1_k127_4462463_4 MORN repeat-containing protein - - - 0.0000000000001286 84.0
PYH1_k127_4462463_5 domain protein - - - 0.0002488 47.0
PYH1_k127_4467559_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 6.409e-265 898.0
PYH1_k127_4467559_1 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 2.551e-258 805.0
PYH1_k127_4467559_10 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 422.0
PYH1_k127_4467559_11 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 437.0
PYH1_k127_4467559_12 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH1_k127_4467559_13 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 350.0
PYH1_k127_4467559_14 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 286.0
PYH1_k127_4467559_15 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003758 284.0
PYH1_k127_4467559_16 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009836 269.0
PYH1_k127_4467559_17 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009532 267.0
PYH1_k127_4467559_18 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000002172 244.0
PYH1_k127_4467559_19 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000009906 234.0
PYH1_k127_4467559_2 Putative diguanylate phosphodiesterase - - - 3.399e-228 742.0
PYH1_k127_4467559_20 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000001667 221.0
PYH1_k127_4467559_21 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000004575 210.0
PYH1_k127_4467559_22 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000001184 207.0
PYH1_k127_4467559_23 dehydratase - - - 0.000000000000000000000000000000000000000000000000004008 185.0
PYH1_k127_4467559_24 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000000000000000000000000000000000000000001302 176.0
PYH1_k127_4467559_25 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000000000000000000006384 179.0
PYH1_k127_4467559_26 phosphorelay signal transduction system K11443 - - 0.000000000000000000000000000000000318 148.0
PYH1_k127_4467559_27 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000001187 121.0
PYH1_k127_4467559_28 Protein of unknown function (DUF3301) - - - 0.000000000000000000003314 96.0
PYH1_k127_4467559_29 - - - - 0.0000000003314 71.0
PYH1_k127_4467559_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 9.262e-212 669.0
PYH1_k127_4467559_4 Receptor family ligand binding region - - - 3.226e-208 662.0
PYH1_k127_4467559_5 PFAM Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 556.0
PYH1_k127_4467559_6 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 480.0
PYH1_k127_4467559_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 437.0
PYH1_k127_4467559_8 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 431.0
PYH1_k127_4467559_9 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 420.0
PYH1_k127_4491872_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 512.0
PYH1_k127_4491872_1 type 4 pilus biogenesis protein K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000001401 239.0
PYH1_k127_4491872_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000001098 230.0
PYH1_k127_4491872_3 Enoyl-CoA hydratase - - - 0.000000000000000000000000000002652 124.0
PYH1_k127_4491872_4 Helix-turn-helix domain K15539 - - 0.00000000000003924 84.0
PYH1_k127_4495051_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1360.0
PYH1_k127_4505592_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 419.0
PYH1_k127_4505592_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 367.0
PYH1_k127_4505592_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002382 283.0
PYH1_k127_4505592_3 Solute carrier family 35 - - - 0.0000000000000000000000000000000000000000000008948 177.0
PYH1_k127_4505592_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000006015 162.0
PYH1_k127_4517109_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 342.0
PYH1_k127_4517109_1 serine threonine protein kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 319.0
PYH1_k127_4517109_2 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000004678 221.0
PYH1_k127_4517109_3 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000001203 156.0
PYH1_k127_4517109_4 - - - - 0.00000000000000000000000002344 115.0
PYH1_k127_4536055_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.451e-308 954.0
PYH1_k127_4536055_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.113e-246 768.0
PYH1_k127_4536055_10 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 291.0
PYH1_k127_4536055_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002292 291.0
PYH1_k127_4536055_12 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 257.0
PYH1_k127_4536055_13 Acetolactate synthase small K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
PYH1_k127_4536055_14 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000000009917 199.0
PYH1_k127_4536055_15 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000000000001816 138.0
PYH1_k127_4536055_16 - K01611 - 4.1.1.50 0.00000005474 59.0
PYH1_k127_4536055_17 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000001475 55.0
PYH1_k127_4536055_2 Adenylate cyclase K01768 - 4.6.1.1 5.124e-215 682.0
PYH1_k127_4536055_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 570.0
PYH1_k127_4536055_4 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 472.0
PYH1_k127_4536055_5 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 411.0
PYH1_k127_4536055_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 362.0
PYH1_k127_4536055_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 307.0
PYH1_k127_4536055_8 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 317.0
PYH1_k127_4536055_9 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 311.0
PYH1_k127_4538809_0 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 325.0
PYH1_k127_4538809_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000001652 218.0
PYH1_k127_4538809_2 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000022 96.0
PYH1_k127_4541913_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.413e-241 758.0
PYH1_k127_4541913_1 Nitrile hydratase K01721,K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000006986 255.0
PYH1_k127_4541913_2 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000000000000805 198.0
PYH1_k127_4541913_3 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000005533 150.0
PYH1_k127_4541913_4 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000000000000000001862 140.0
PYH1_k127_4541913_5 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000000003735 134.0
PYH1_k127_4541913_6 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000008939 132.0
PYH1_k127_4546634_0 RmlD substrate binding domain K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 422.0
PYH1_k127_4546634_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 333.0
PYH1_k127_4546634_2 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 317.0
PYH1_k127_4546634_3 Hemolysin-type calcium-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001786 264.0
PYH1_k127_4546634_4 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000004418 198.0
PYH1_k127_4576605_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 3.439e-210 665.0
PYH1_k127_4576605_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 541.0
PYH1_k127_4576605_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 307.0
PYH1_k127_4576605_3 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 300.0
PYH1_k127_4576605_4 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006986 285.0
PYH1_k127_4576605_5 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000185 248.0
PYH1_k127_4576605_6 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000009771 189.0
PYH1_k127_4576605_7 Belongs to the DnaA family K10763 - - 0.0000000000000000099 85.0
PYH1_k127_4576605_8 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.00000001675 61.0
PYH1_k127_4582184_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1283.0
PYH1_k127_4582184_1 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 3.321e-240 755.0
PYH1_k127_4582184_10 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 320.0
PYH1_k127_4582184_11 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002006 247.0
PYH1_k127_4582184_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000006748 231.0
PYH1_k127_4582184_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000006244 199.0
PYH1_k127_4582184_14 KR domain - - - 0.000000000000000000000000000000000000000005992 167.0
PYH1_k127_4582184_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000001009 141.0
PYH1_k127_4582184_16 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000003067 119.0
PYH1_k127_4582184_17 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000002547 86.0
PYH1_k127_4582184_18 - - - - 0.000000000000129 73.0
PYH1_k127_4582184_2 type II secretion system protein K02653 - - 2.101e-197 622.0
PYH1_k127_4582184_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 612.0
PYH1_k127_4582184_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 505.0
PYH1_k127_4582184_5 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 455.0
PYH1_k127_4582184_6 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 370.0
PYH1_k127_4582184_7 SMART AAA ATPase K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 364.0
PYH1_k127_4582184_8 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 356.0
PYH1_k127_4582184_9 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 323.0
PYH1_k127_4589769_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 6.183e-319 1023.0
PYH1_k127_4589769_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 3.685e-263 841.0
PYH1_k127_4589769_10 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000005926 212.0
PYH1_k127_4589769_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000005654 202.0
PYH1_k127_4589769_12 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000002866 105.0
PYH1_k127_4589769_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 448.0
PYH1_k127_4589769_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 359.0
PYH1_k127_4589769_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 342.0
PYH1_k127_4589769_5 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 325.0
PYH1_k127_4589769_6 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 329.0
PYH1_k127_4589769_7 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 330.0
PYH1_k127_4589769_8 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 308.0
PYH1_k127_4589769_9 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000004475 216.0
PYH1_k127_459612_0 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 488.0
PYH1_k127_459612_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 394.0
PYH1_k127_459612_2 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002642 253.0
PYH1_k127_459954_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.201e-241 764.0
PYH1_k127_459954_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.624e-241 758.0
PYH1_k127_459954_10 prepilin-type N-terminal cleavage methylation K02456 - - 0.000000000000000000000000000000000000000000000000000000005359 203.0
PYH1_k127_459954_11 prepilin-type N-terminal cleavage methylation K02456 - - 0.00000000000000000000000000000000000000000002763 166.0
PYH1_k127_459954_12 Type II secretory pathway pseudopilin - - - 0.00000000000000000000000000000000000000005165 166.0
PYH1_k127_459954_13 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000001656 66.0
PYH1_k127_459954_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.093e-211 663.0
PYH1_k127_459954_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 397.0
PYH1_k127_459954_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 381.0
PYH1_k127_459954_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 329.0
PYH1_k127_459954_6 Phenylacetic acid degradation protein PaaY K08279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
PYH1_k127_459954_7 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000002185 261.0
PYH1_k127_459954_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000002484 229.0
PYH1_k127_459954_9 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001144 211.0
PYH1_k127_4619428_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.78e-214 674.0
PYH1_k127_4619428_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 546.0
PYH1_k127_4619428_10 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001025 279.0
PYH1_k127_4619428_11 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001938 224.0
PYH1_k127_4619428_12 NIPSNAP - - - 0.000000000000000000000000000000000000000000000007723 176.0
PYH1_k127_4619428_13 - - - - 0.0000000000000000000000000000000000000000458 158.0
PYH1_k127_4619428_14 Cysteine dioxygenase type I - - - 0.00000000000000000000000000000000000000329 153.0
PYH1_k127_4619428_15 Cupin 2, conserved barrel K21700 - - 0.00000000000000000000000000000003508 133.0
PYH1_k127_4619428_16 Protein of unknown function (DUF3567) - - - 0.00000000000000002949 83.0
PYH1_k127_4619428_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 526.0
PYH1_k127_4619428_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 537.0
PYH1_k127_4619428_4 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 422.0
PYH1_k127_4619428_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 402.0
PYH1_k127_4619428_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 324.0
PYH1_k127_4619428_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 299.0
PYH1_k127_4619428_8 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002243 289.0
PYH1_k127_4619428_9 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
PYH1_k127_46356_0 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 433.0
PYH1_k127_46356_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000001835 236.0
PYH1_k127_46356_2 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000001313 128.0
PYH1_k127_4652575_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.297e-230 726.0
PYH1_k127_4652575_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 616.0
PYH1_k127_4652575_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 442.0
PYH1_k127_4652575_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000001505 195.0
PYH1_k127_4652575_4 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000019 100.0
PYH1_k127_4652575_5 enzyme of heme biosynthesis K02498 - - 0.0000000001717 63.0
PYH1_k127_4698165_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 585.0
PYH1_k127_4698165_1 Histidine kinase K08082 - 2.7.13.3 0.000000001838 70.0
PYH1_k127_4702947_0 COG1538 Outer membrane protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 402.0
PYH1_k127_4702947_1 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
PYH1_k127_4702947_2 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000003099 209.0
PYH1_k127_4702947_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000003899 152.0
PYH1_k127_4704543_0 twitching motility protein K02670 - - 1.22e-202 638.0
PYH1_k127_4704543_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 619.0
PYH1_k127_4704543_10 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000007797 94.0
PYH1_k127_4704543_2 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 469.0
PYH1_k127_4704543_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 402.0
PYH1_k127_4704543_4 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 413.0
PYH1_k127_4704543_5 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 297.0
PYH1_k127_4704543_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 278.0
PYH1_k127_4704543_7 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000001975 217.0
PYH1_k127_4704543_8 VanZ like family - - - 0.0000000000000000000000000000000000000000000000008771 182.0
PYH1_k127_4704543_9 Ferredoxin - - - 0.0000000000000000000000000000000000000000000003933 168.0
PYH1_k127_4741067_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1138.0
PYH1_k127_4741067_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 471.0
PYH1_k127_4741067_10 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000001068 98.0
PYH1_k127_4741067_11 import inner membrane translocase subunit Tim44 - - - 0.0005763 44.0
PYH1_k127_4741067_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 366.0
PYH1_k127_4741067_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 355.0
PYH1_k127_4741067_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 346.0
PYH1_k127_4741067_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 332.0
PYH1_k127_4741067_6 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006857 261.0
PYH1_k127_4741067_7 - - - - 0.00000000000000000000000000000000000000000000000315 184.0
PYH1_k127_4741067_8 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000003353 179.0
PYH1_k127_4741067_9 Protein of unknown function (DUF2782) - - - 0.00000000000000000000004527 104.0
PYH1_k127_4752798_0 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 409.0
PYH1_k127_4752798_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000003109 228.0
PYH1_k127_4752798_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000003495 222.0
PYH1_k127_4752798_3 ABC transporter - - - 0.000000000000000000000000000000000000000002754 156.0
PYH1_k127_4752798_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000008205 145.0
PYH1_k127_4753806_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 544.0
PYH1_k127_4753806_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 470.0
PYH1_k127_4753806_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 430.0
PYH1_k127_4753806_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000004618 221.0
PYH1_k127_4753806_4 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000009806 185.0
PYH1_k127_4795450_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.078e-276 854.0
PYH1_k127_4795450_1 Class II Aldolase and Adducin N-terminal domain - - - 2.029e-271 852.0
PYH1_k127_4795450_10 PAP2 superfamily K19803 - 2.7.4.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003049 303.0
PYH1_k127_4795450_11 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000006597 231.0
PYH1_k127_4795450_12 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002936 233.0
PYH1_k127_4795450_13 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000007158 226.0
PYH1_k127_4795450_14 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000007372 235.0
PYH1_k127_4795450_15 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000002233 220.0
PYH1_k127_4795450_16 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000007081 215.0
PYH1_k127_4795450_17 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000003739 209.0
PYH1_k127_4795450_18 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000006557 198.0
PYH1_k127_4795450_19 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000000001596 168.0
PYH1_k127_4795450_2 arylsulfatase A K01130 - 3.1.6.1 1.482e-268 840.0
PYH1_k127_4795450_20 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004611 168.0
PYH1_k127_4795450_21 pilus assembly protein PilZ K02676 - - 0.00000000000000000000000000000000000001127 161.0
PYH1_k127_4795450_22 ankyrin repeat K06867 - - 0.0000000000000000000000000000000000005997 148.0
PYH1_k127_4795450_23 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000342 139.0
PYH1_k127_4795450_24 Sh3 type 3 domain protein - - - 0.000000000000000000000000000785 121.0
PYH1_k127_4795450_25 Tetratricopeptide repeat - - - 0.00000000000000000005683 93.0
PYH1_k127_4795450_26 Domain of unknown function (DUF4124) - - - 0.00000000000002824 85.0
PYH1_k127_4795450_27 STAS domain - - - 0.00000000004635 68.0
PYH1_k127_4795450_28 - - - - 0.00001922 55.0
PYH1_k127_4795450_29 Domain of unknown function (DUF4936) - - - 0.000202 55.0
PYH1_k127_4795450_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.619e-237 742.0
PYH1_k127_4795450_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 485.0
PYH1_k127_4795450_5 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 422.0
PYH1_k127_4795450_6 polysaccharide biosynthetic process K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 419.0
PYH1_k127_4795450_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 395.0
PYH1_k127_4795450_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 385.0
PYH1_k127_4795450_9 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
PYH1_k127_4824728_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.785e-245 769.0
PYH1_k127_4824728_1 Cytochrome b(N-terminal)/b6/petB - - - 3.05e-241 773.0
PYH1_k127_4824728_10 - - - - 0.0000000000004585 70.0
PYH1_k127_4824728_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 387.0
PYH1_k127_4824728_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 396.0
PYH1_k127_4824728_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 344.0
PYH1_k127_4824728_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 323.0
PYH1_k127_4824728_6 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004411 271.0
PYH1_k127_4824728_7 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000007857 242.0
PYH1_k127_4824728_8 - - - - 0.0000000000000000000000000000000002311 145.0
PYH1_k127_4824728_9 - - - - 0.00000000000000000000001052 117.0
PYH1_k127_4837051_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1176.0
PYH1_k127_4837051_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.637e-287 893.0
PYH1_k127_4837051_10 dehydratase - - - 0.000000000000000000000000000000000000000000000001487 185.0
PYH1_k127_4837051_11 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000001823 184.0
PYH1_k127_4837051_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000001434 164.0
PYH1_k127_4837051_13 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000005106 143.0
PYH1_k127_4837051_14 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000007857 139.0
PYH1_k127_4837051_15 Ribonuclease K01167 - 3.1.27.3 0.00000000000000000000000000000004243 128.0
PYH1_k127_4837051_16 Putative regulatory protein - - - 0.00000000000000000000000000000385 121.0
PYH1_k127_4837051_17 Barstar (barnase inhibitor) - - - 0.000000000000000002757 89.0
PYH1_k127_4837051_18 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000004974 84.0
PYH1_k127_4837051_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 417.0
PYH1_k127_4837051_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 377.0
PYH1_k127_4837051_4 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 329.0
PYH1_k127_4837051_5 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 287.0
PYH1_k127_4837051_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 257.0
PYH1_k127_4837051_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000003812 222.0
PYH1_k127_4837051_8 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000004308 192.0
PYH1_k127_4837051_9 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000615 193.0
PYH1_k127_4903741_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 2.336e-313 970.0
PYH1_k127_4903741_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 363.0
PYH1_k127_4903741_2 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000000000002113 227.0
PYH1_k127_4903741_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000006833 207.0
PYH1_k127_4903741_4 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000001337 176.0
PYH1_k127_4903741_5 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000147 165.0
PYH1_k127_4903741_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000002895 162.0
PYH1_k127_4903741_7 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000000002105 149.0
PYH1_k127_4963502_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1180.0
PYH1_k127_4963502_1 Sulfate transporter antisigma-factor antagonist STAS - - - 1.5e-238 757.0
PYH1_k127_4963502_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 387.0
PYH1_k127_4963502_11 Membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 347.0
PYH1_k127_4963502_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 358.0
PYH1_k127_4963502_13 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 340.0
PYH1_k127_4963502_14 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 340.0
PYH1_k127_4963502_15 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 313.0
PYH1_k127_4963502_16 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001312 283.0
PYH1_k127_4963502_17 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 262.0
PYH1_k127_4963502_18 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 261.0
PYH1_k127_4963502_19 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 250.0
PYH1_k127_4963502_2 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 3.331e-232 724.0
PYH1_k127_4963502_20 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000004979 229.0
PYH1_k127_4963502_21 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000003923 228.0
PYH1_k127_4963502_22 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000007935 222.0
PYH1_k127_4963502_23 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000538 203.0
PYH1_k127_4963502_24 Phasin protein - - - 0.00000000000000000000000000000000000000000000000001548 186.0
PYH1_k127_4963502_25 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000001733 181.0
PYH1_k127_4963502_26 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000003077 171.0
PYH1_k127_4963502_27 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000001589 163.0
PYH1_k127_4963502_28 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000003496 172.0
PYH1_k127_4963502_29 - - - - 0.0000000000000000000000000000000000000000004733 168.0
PYH1_k127_4963502_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 4.729e-209 658.0
PYH1_k127_4963502_30 Cold shock K03704 - - 0.00000000000000000000000000000000001552 137.0
PYH1_k127_4963502_31 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000001105 122.0
PYH1_k127_4963502_32 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000001259 136.0
PYH1_k127_4963502_33 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000002983 130.0
PYH1_k127_4963502_34 Cytochrome c, class I - - - 0.000000000000000000000001477 107.0
PYH1_k127_4963502_35 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000001369 95.0
PYH1_k127_4963502_36 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.00000000000001935 74.0
PYH1_k127_4963502_37 STAS domain K03321 - - 0.000005754 49.0
PYH1_k127_4963502_4 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 565.0
PYH1_k127_4963502_5 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 515.0
PYH1_k127_4963502_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 475.0
PYH1_k127_4963502_7 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 428.0
PYH1_k127_4963502_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 417.0
PYH1_k127_4963502_9 mechanosensitive K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 393.0
PYH1_k127_5133777_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 463.0
PYH1_k127_5133777_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 439.0
PYH1_k127_5133777_2 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 331.0
PYH1_k127_5133777_3 abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 348.0
PYH1_k127_5133777_4 dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
PYH1_k127_5133777_5 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001044 235.0
PYH1_k127_5133777_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000005937 222.0
PYH1_k127_5166251_0 Protein of unknown function (DUF1116) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 536.0
PYH1_k127_5166251_1 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 366.0
PYH1_k127_5175727_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 374.0
PYH1_k127_5175727_1 - - - - 0.00000000000000000000000000000000007857 140.0
PYH1_k127_5175727_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000002398 108.0
PYH1_k127_518635_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.809e-223 701.0
PYH1_k127_518635_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000002456 205.0
PYH1_k127_518635_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000003344 200.0
PYH1_k127_518635_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000009283 169.0
PYH1_k127_5239123_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.836e-299 926.0
PYH1_k127_5239123_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004531 278.0
PYH1_k127_5239123_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000008463 129.0
PYH1_k127_5240148_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.523e-321 990.0
PYH1_k127_5240148_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 435.0
PYH1_k127_5240148_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001016 274.0
PYH1_k127_5240148_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000003414 219.0
PYH1_k127_5270051_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 613.0
PYH1_k127_5270051_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 612.0
PYH1_k127_5270051_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 402.0
PYH1_k127_5270051_3 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 339.0
PYH1_k127_5270051_4 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 302.0
PYH1_k127_5270051_5 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 306.0
PYH1_k127_5270051_6 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000003625 273.0
PYH1_k127_5270051_7 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 280.0
PYH1_k127_5270051_8 cyclopropane-fatty-acyl-phospholipid synthase K00574 - - - 0.00000000000000000000000000008603 117.0
PYH1_k127_5270051_9 Sh3 type 3 domain protein - - - 0.000000000754 71.0
PYH1_k127_5299982_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 2.31e-199 638.0
PYH1_k127_5299982_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 488.0
PYH1_k127_5299982_2 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 420.0
PYH1_k127_5299982_3 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 388.0
PYH1_k127_5299982_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 349.0
PYH1_k127_5299982_5 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001294 269.0
PYH1_k127_5299982_6 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000003727 79.0
PYH1_k127_5306688_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.502e-204 644.0
PYH1_k127_5306688_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 567.0
PYH1_k127_5330393_0 Transporter - - - 3.128e-214 699.0
PYH1_k127_5330393_1 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 305.0
PYH1_k127_5330393_2 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000004688 187.0
PYH1_k127_5330393_3 Passenger-associated-transport-repeat - - - 0.00000000000000000001139 103.0
PYH1_k127_5338238_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.043e-212 680.0
PYH1_k127_5338238_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 536.0
PYH1_k127_5338238_2 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004691 231.0
PYH1_k127_5338238_3 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000003536 193.0
PYH1_k127_5338238_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000008343 124.0
PYH1_k127_5338238_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000003683 70.0
PYH1_k127_5338249_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 464.0
PYH1_k127_5338249_1 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.0000000000000000000000000000000000000002515 167.0
PYH1_k127_5338249_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000001915 61.0
PYH1_k127_5360686_0 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 322.0
PYH1_k127_5360686_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000006012 199.0
PYH1_k127_5360686_2 - - - - 0.0000000000000000000000000000000001483 139.0
PYH1_k127_5360686_3 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000001077 73.0
PYH1_k127_5380572_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1813.0
PYH1_k127_5489885_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 613.0
PYH1_k127_5489885_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 478.0
PYH1_k127_5489885_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 421.0
PYH1_k127_5489885_3 Peptidase family M23 K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 317.0
PYH1_k127_5489885_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000002646 80.0
PYH1_k127_5489885_5 Protein of unknown function (DUF721) - - - 0.00000000129 70.0
PYH1_k127_5497238_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.756e-287 889.0
PYH1_k127_5497238_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 494.0
PYH1_k127_5497238_2 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 376.0
PYH1_k127_5497238_3 oxidase assembly K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008407 242.0
PYH1_k127_5497238_4 Protein of unknown function (DUF2909) - - - 0.000000000000855 72.0
PYH1_k127_5497238_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000003358 58.0
PYH1_k127_5497238_6 Protein of unknown function (DUF2970) - - - 0.0008198 50.0
PYH1_k127_5516986_0 alpha/beta hydrolase fold K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 358.0
PYH1_k127_5516986_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000599 232.0
PYH1_k127_5516986_2 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000004661 225.0
PYH1_k127_5516986_3 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000000000002069 181.0
PYH1_k127_5526542_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.003e-283 907.0
PYH1_k127_5526542_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969,K13778 - 6.4.1.4,6.4.1.5 5.423e-233 746.0
PYH1_k127_5526542_10 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 375.0
PYH1_k127_5526542_11 type I secretion membrane fusion K02022,K12537 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 348.0
PYH1_k127_5526542_12 lipolytic protein G-D-S-L family K20306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008573 270.0
PYH1_k127_5526542_13 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001893 254.0
PYH1_k127_5526542_14 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000001549 267.0
PYH1_k127_5526542_15 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000001294 182.0
PYH1_k127_5526542_16 Response regulator, receiver - - - 0.00000000000000000000000000000000000001082 153.0
PYH1_k127_5526542_17 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000003898 140.0
PYH1_k127_5526542_18 Thioesterase superfamily - - - 0.0000000000000000000000000000000005238 149.0
PYH1_k127_5526542_19 Subtilase family K14645 - - 0.0000000000000000000000000000009457 127.0
PYH1_k127_5526542_2 Belongs to the thiolase family K00626 - 2.3.1.9 1.61e-197 621.0
PYH1_k127_5526542_20 PFAM CopG domain protein DNA-binding domain protein - - - 0.00000000000004407 78.0
PYH1_k127_5526542_3 acyl-CoA dehydrogenase K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 593.0
PYH1_k127_5526542_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 569.0
PYH1_k127_5526542_5 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 534.0
PYH1_k127_5526542_6 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 517.0
PYH1_k127_5526542_7 Type I secretion system K16299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 484.0
PYH1_k127_5526542_8 Acetyl propionyl-CoA carboxylase, alpha subunit K01968,K13777 - 6.4.1.4,6.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 449.0
PYH1_k127_5526542_9 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 443.0
PYH1_k127_5546686_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 454.0
PYH1_k127_5546686_1 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
PYH1_k127_5546686_2 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000009627 268.0
PYH1_k127_5546686_3 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000005817 262.0
PYH1_k127_5546686_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
PYH1_k127_5546686_5 Methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000002806 192.0
PYH1_k127_5546686_6 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.00000000000000000000000000000000000000000000000002034 190.0
PYH1_k127_5546686_7 -Thioesterase K01075 - 3.1.2.23 0.000000000000000000004889 98.0
PYH1_k127_5565043_0 Oxidoreductase - - - 2.352e-203 647.0
PYH1_k127_5565043_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000001837 191.0
PYH1_k127_5565043_2 Copper binding periplasmic protein CusF - - - 0.00000000000000000000000000001349 119.0
PYH1_k127_5567211_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003841 284.0
PYH1_k127_5567211_1 NUDIX domain - - - 0.00000000000000000000000000000000000000000000002093 173.0
PYH1_k127_5598747_0 Domain of unknown function (DUF3394) - - - 9.124e-232 726.0
PYH1_k127_5598747_1 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 478.0
PYH1_k127_5598747_2 Tartrate K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 451.0
PYH1_k127_5598747_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 368.0
PYH1_k127_5598747_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 335.0
PYH1_k127_5598747_5 Fumarate K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 323.0
PYH1_k127_5598747_6 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000002655 188.0
PYH1_k127_5598747_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000000000001161 141.0
PYH1_k127_5602311_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 547.0
PYH1_k127_5602311_1 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 506.0
PYH1_k127_5602311_10 - - - - 0.0000000000000000000000001009 109.0
PYH1_k127_5602311_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 485.0
PYH1_k127_5602311_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 431.0
PYH1_k127_5602311_4 PFAM sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 411.0
PYH1_k127_5602311_5 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 377.0
PYH1_k127_5602311_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 300.0
PYH1_k127_5602311_7 CBS domain - - - 0.000000000000000000000000000000000000000000974 173.0
PYH1_k127_5602311_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000009731 146.0
PYH1_k127_5602311_9 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000156 138.0
PYH1_k127_561446_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1507.0
PYH1_k127_561446_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 2.737e-199 641.0
PYH1_k127_561446_10 - - - - 0.0000000000000000000001564 113.0
PYH1_k127_561446_11 - - - - 0.000000000000001515 87.0
PYH1_k127_561446_12 - - - - 0.00000002863 58.0
PYH1_k127_561446_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 602.0
PYH1_k127_561446_3 4Fe-4S dicluster domain K00124,K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 398.0
PYH1_k127_561446_4 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 347.0
PYH1_k127_561446_5 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 304.0
PYH1_k127_561446_6 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000168 274.0
PYH1_k127_561446_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000003138 213.0
PYH1_k127_561446_8 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000008057 134.0
PYH1_k127_561446_9 Chaperone protein TorD - - - 0.000000000000000000000000000006407 130.0
PYH1_k127_5642422_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 5.823e-276 859.0
PYH1_k127_5642422_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 300.0
PYH1_k127_5642422_2 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 293.0
PYH1_k127_5642422_3 PFAM fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 290.0
PYH1_k127_5642422_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K15919,K18606 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009853,GO:0009854,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0043094,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.237 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002374 302.0
PYH1_k127_5642422_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001164 273.0
PYH1_k127_5642422_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000005499 206.0
PYH1_k127_5669690_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 539.0
PYH1_k127_5699876_0 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 563.0
PYH1_k127_5699876_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000001558 191.0
PYH1_k127_5707425_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1495.0
PYH1_k127_5707425_1 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 1.489e-294 922.0
PYH1_k127_5707425_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 527.0
PYH1_k127_5707425_11 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 458.0
PYH1_k127_5707425_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 326.0
PYH1_k127_5707425_13 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 310.0
PYH1_k127_5707425_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 311.0
PYH1_k127_5707425_15 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 300.0
PYH1_k127_5707425_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000007121 290.0
PYH1_k127_5707425_17 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006731 262.0
PYH1_k127_5707425_18 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001648 274.0
PYH1_k127_5707425_19 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000002297 236.0
PYH1_k127_5707425_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.015e-289 898.0
PYH1_k127_5707425_20 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001307 247.0
PYH1_k127_5707425_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000002706 215.0
PYH1_k127_5707425_22 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000003262 207.0
PYH1_k127_5707425_23 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000001942 205.0
PYH1_k127_5707425_24 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000002751 211.0
PYH1_k127_5707425_25 Branched-chain amino acid permease - - - 0.0000000000000000000000000000000000000000000000000891 186.0
PYH1_k127_5707425_26 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000002565 186.0
PYH1_k127_5707425_27 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000123 177.0
PYH1_k127_5707425_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000009982 169.0
PYH1_k127_5707425_29 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000006162 159.0
PYH1_k127_5707425_3 chain 5 L K00341 - 1.6.5.3 1.14e-278 869.0
PYH1_k127_5707425_30 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000000000000000001957 130.0
PYH1_k127_5707425_31 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000002536 87.0
PYH1_k127_5707425_32 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.00006289 46.0
PYH1_k127_5707425_4 Belongs to the peptidase M16 family K07263 - - 3.171e-268 863.0
PYH1_k127_5707425_5 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.364e-247 771.0
PYH1_k127_5707425_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.358e-233 739.0
PYH1_k127_5707425_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.859e-232 736.0
PYH1_k127_5707425_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 569.0
PYH1_k127_5707425_9 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 547.0
PYH1_k127_5728271_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000009455 228.0
PYH1_k127_577788_0 RNB K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 619.0
PYH1_k127_577788_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 606.0
PYH1_k127_577788_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000006918 187.0
PYH1_k127_577788_3 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000001371 187.0
PYH1_k127_577788_4 - - - - 0.000000000000000000000000000000000000000000005515 170.0
PYH1_k127_577788_5 Redoxin family - - - 0.00000000000000000000000000000000001199 146.0
PYH1_k127_577788_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000000000002797 109.0
PYH1_k127_577788_7 TonB C terminal K03832 - - 0.00003714 49.0
PYH1_k127_5823473_0 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 364.0
PYH1_k127_5823473_1 cytochrome c-type protein K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001017 282.0
PYH1_k127_5823473_2 Ferredoxin-type protein K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002266 269.0
PYH1_k127_5823473_3 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000001477 162.0
PYH1_k127_5823473_4 Ammonium transporter K03320 - - 0.0000000000000008131 77.0
PYH1_k127_5838378_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 393.0
PYH1_k127_5838378_1 cell division K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 297.0
PYH1_k127_5838378_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000003221 116.0
PYH1_k127_5871234_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1391.0
PYH1_k127_5871234_1 Belongs to the TPP enzyme family K01577 - 4.1.1.8 1.279e-306 944.0
PYH1_k127_5871234_10 Transcriptional regulator, Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000002296 60.0
PYH1_k127_5871234_2 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 5.23e-267 875.0
PYH1_k127_5871234_3 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 4.614e-246 769.0
PYH1_k127_5871234_4 Tripartite tricarboxylate transporter TctA family K07793 - - 1.944e-242 756.0
PYH1_k127_5871234_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 497.0
PYH1_k127_5871234_6 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 325.0
PYH1_k127_5871234_7 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007809 268.0
PYH1_k127_5871234_8 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008744 249.0
PYH1_k127_5871234_9 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000008537 172.0
PYH1_k127_5891845_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.542e-225 719.0
PYH1_k127_5891845_1 CoA-binding domain - - - 1.458e-198 650.0
PYH1_k127_5891845_10 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000142 212.0
PYH1_k127_5891845_11 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000002903 203.0
PYH1_k127_5891845_12 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000006086 202.0
PYH1_k127_5891845_13 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000001059 156.0
PYH1_k127_5891845_2 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 507.0
PYH1_k127_5891845_3 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 448.0
PYH1_k127_5891845_4 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 413.0
PYH1_k127_5891845_5 Glycosyltransferase Family 4 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 373.0
PYH1_k127_5891845_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 359.0
PYH1_k127_5891845_7 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007397 284.0
PYH1_k127_5891845_8 PFAM Glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003035 268.0
PYH1_k127_5891845_9 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001663 253.0
PYH1_k127_5923074_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 540.0
PYH1_k127_5923074_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 521.0
PYH1_k127_5923074_10 RDD family - - - 0.0000000000000000000000000000000000000000000000006198 179.0
PYH1_k127_5923074_11 Thioesterase superfamily protein - - - 0.000000000000000000000000162 112.0
PYH1_k127_5923074_12 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000001597 99.0
PYH1_k127_5923074_2 Belongs to the GMC oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 512.0
PYH1_k127_5923074_3 13-prostaglandin reductase activity K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 414.0
PYH1_k127_5923074_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 354.0
PYH1_k127_5923074_5 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 345.0
PYH1_k127_5923074_6 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 323.0
PYH1_k127_5923074_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 335.0
PYH1_k127_5923074_8 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 317.0
PYH1_k127_5923074_9 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007419 247.0
PYH1_k127_5940440_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 557.0
PYH1_k127_5940440_1 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 389.0
PYH1_k127_5940440_10 6-phosphogluconolactonase activity - - - 0.00000000003137 77.0
PYH1_k127_5940440_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 349.0
PYH1_k127_5940440_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001146 267.0
PYH1_k127_5940440_4 haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000001101 249.0
PYH1_k127_5940440_5 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001645 245.0
PYH1_k127_5940440_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000002062 189.0
PYH1_k127_5940440_7 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000002155 190.0
PYH1_k127_5940440_8 OmpA family K03286 - - 0.0000000000000000000000000000000000001558 145.0
PYH1_k127_5940440_9 Domain of unknown function (DUF4347) - - - 0.00000000000000008941 95.0
PYH1_k127_5965351_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 422.0
PYH1_k127_5965351_1 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000002622 231.0
PYH1_k127_5995062_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 2.815e-294 911.0
PYH1_k127_5995062_1 Cytochrome c K02198 - - 1.328e-276 863.0
PYH1_k127_5995062_10 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000478 143.0
PYH1_k127_5995062_11 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000005046 123.0
PYH1_k127_5995062_12 lipid carrier protein - - - 0.000000000000000000000005208 111.0
PYH1_k127_5995062_13 Hemerythrin HHE cation binding domain - - - 0.000000000000000004973 93.0
PYH1_k127_5995062_14 Uncharacterized conserved protein (DUF2249) - - - 0.000000000313 69.0
PYH1_k127_5995062_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000001744 59.0
PYH1_k127_5995062_2 cytochrome - - - 1.823e-239 750.0
PYH1_k127_5995062_3 Peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 513.0
PYH1_k127_5995062_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 392.0
PYH1_k127_5995062_5 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 334.0
PYH1_k127_5995062_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001715 261.0
PYH1_k127_5995062_7 Redoxin K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000007666 248.0
PYH1_k127_5995062_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000003409 219.0
PYH1_k127_5995062_9 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000001507 214.0
PYH1_k127_5997567_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.439e-266 828.0
PYH1_k127_5997567_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.622e-226 708.0
PYH1_k127_5997567_10 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 413.0
PYH1_k127_5997567_11 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 366.0
PYH1_k127_5997567_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 356.0
PYH1_k127_5997567_13 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 357.0
PYH1_k127_5997567_14 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 316.0
PYH1_k127_5997567_15 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006082 282.0
PYH1_k127_5997567_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003867 277.0
PYH1_k127_5997567_17 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000046 271.0
PYH1_k127_5997567_18 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000002242 271.0
PYH1_k127_5997567_19 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000351 278.0
PYH1_k127_5997567_2 Amidohydrolase family - - - 2.33e-214 678.0
PYH1_k127_5997567_20 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000626 259.0
PYH1_k127_5997567_21 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000003538 248.0
PYH1_k127_5997567_22 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000114 219.0
PYH1_k127_5997567_23 Acyl-transferase - - - 0.000000000000000000000000000000000000000003692 174.0
PYH1_k127_5997567_24 FtsX-like permease family K02004 - - 0.00000000000001021 76.0
PYH1_k127_5997567_25 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0002475 49.0
PYH1_k127_5997567_3 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 544.0
PYH1_k127_5997567_4 TatD related DNase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 506.0
PYH1_k127_5997567_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 493.0
PYH1_k127_5997567_6 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 435.0
PYH1_k127_5997567_7 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 444.0
PYH1_k127_5997567_8 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 409.0
PYH1_k127_5997567_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 432.0
PYH1_k127_6022963_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 350.0
PYH1_k127_6022963_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 343.0
PYH1_k127_6022963_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 259.0
PYH1_k127_6022963_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000001271 198.0
PYH1_k127_6022963_4 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000004986 51.0
PYH1_k127_6058238_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 574.0
PYH1_k127_6058238_1 abc transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 483.0
PYH1_k127_6058238_2 PFAM HpcH HpaI aldolase citrate lyase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 324.0
PYH1_k127_6058238_3 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 280.0
PYH1_k127_6058238_4 nucleic-acid-binding protein contains PIN domain - - - 0.000000000000000000000000004075 116.0
PYH1_k127_6058238_5 Domain of unknown function (DUF4410) - - - 0.0003498 50.0
PYH1_k127_6065580_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1163.0
PYH1_k127_6065580_1 Belongs to the TPP enzyme family K01577 - 4.1.1.8 0.0 1004.0
PYH1_k127_6065580_2 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 596.0
PYH1_k127_6065580_3 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 419.0
PYH1_k127_6065580_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 351.0
PYH1_k127_6065580_5 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000002245 191.0
PYH1_k127_6077135_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.392e-267 841.0
PYH1_k127_6077135_1 cytochrome C oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 609.0
PYH1_k127_6077135_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 457.0
PYH1_k127_6077135_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 371.0
PYH1_k127_6077135_4 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 313.0
PYH1_k127_6077135_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000528 281.0
PYH1_k127_6077135_6 FixH family K09926 - - 0.0000000000000000000007406 100.0
PYH1_k127_6077135_7 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000007474 70.0
PYH1_k127_6077135_8 COG4736 Cbb3-type cytochrome oxidase, subunit 3 K00407 - - 0.0000000611 63.0
PYH1_k127_6096351_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 476.0
PYH1_k127_6096351_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 325.0
PYH1_k127_6096351_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000005867 123.0
PYH1_k127_6096351_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002658 94.0
PYH1_k127_6163330_0 - - - - 0.0 1306.0
PYH1_k127_6163330_1 hydrolase activity, acting on ester bonds K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 465.0
PYH1_k127_6163330_10 cytochrome c5 - - - 0.00000000000000000000000000000000000000000001401 171.0
PYH1_k127_6163330_11 Histidine kinase K08082 - 2.7.13.3 0.00001963 47.0
PYH1_k127_6163330_12 Rubrerythrin - - - 0.0001026 48.0
PYH1_k127_6163330_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 370.0
PYH1_k127_6163330_3 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 348.0
PYH1_k127_6163330_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 338.0
PYH1_k127_6163330_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 292.0
PYH1_k127_6163330_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005097 292.0
PYH1_k127_6163330_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000719 224.0
PYH1_k127_6163330_8 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000002138 181.0
PYH1_k127_6163330_9 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000002373 181.0
PYH1_k127_6178676_0 AMP-dependent synthetase - - - 7.972e-276 881.0
PYH1_k127_6178676_1 cyclic nucleotide-binding - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000001059 62.0
PYH1_k127_6179671_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 514.0
PYH1_k127_6179671_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000004689 246.0
PYH1_k127_6179671_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000001487 219.0
PYH1_k127_6179671_3 COG3001 Fructosamine-3-kinase - GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.00000000000000000000000000000000000000000000000000000000000002032 219.0
PYH1_k127_6179671_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000001864 172.0
PYH1_k127_6246810_0 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 556.0
PYH1_k127_6246810_1 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 341.0
PYH1_k127_6246810_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 304.0
PYH1_k127_6246810_3 Glycosyltransferase like family 2 K13002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 279.0
PYH1_k127_6246810_4 ADP-glyceromanno-heptose 6-epimerase activity K19997,K22320 - 1.1.1.412,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000005038 240.0
PYH1_k127_6246810_5 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002274 232.0
PYH1_k127_6250859_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 531.0
PYH1_k127_6250859_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000001156 156.0
PYH1_k127_6275541_0 Aminotransferase K09758 - 4.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 535.0
PYH1_k127_6275541_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 412.0
PYH1_k127_6275541_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 380.0
PYH1_k127_6275541_3 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 361.0
PYH1_k127_6275541_4 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 316.0
PYH1_k127_6275541_5 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 314.0
PYH1_k127_6275541_6 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003061 291.0
PYH1_k127_6275541_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006039 273.0
PYH1_k127_6275541_8 N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000004149 204.0
PYH1_k127_6275541_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000008237 67.0
PYH1_k127_6284681_0 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000001462 192.0
PYH1_k127_6284681_1 SnoaL-like domain - - - 0.00000000000000000000000000000001306 132.0
PYH1_k127_6284681_2 PFAM PsiF repeat protein - - - 0.0000000000000000008591 93.0
PYH1_k127_6284681_3 - - - - 0.000000000000000004056 83.0
PYH1_k127_6284681_4 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000004445 83.0
PYH1_k127_6338308_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 336.0
PYH1_k127_6338308_1 ApaG domain - - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
PYH1_k127_6338308_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000001897 111.0
PYH1_k127_6363115_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1438.0
PYH1_k127_6363115_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.63e-261 816.0
PYH1_k127_6363115_10 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 412.0
PYH1_k127_6363115_11 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 375.0
PYH1_k127_6363115_12 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 339.0
PYH1_k127_6363115_13 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 337.0
PYH1_k127_6363115_14 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 318.0
PYH1_k127_6363115_15 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 314.0
PYH1_k127_6363115_16 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 317.0
PYH1_k127_6363115_17 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 310.0
PYH1_k127_6363115_18 B-1 B cell differentiation K03634,K14166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 300.0
PYH1_k127_6363115_19 zinc protease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 290.0
PYH1_k127_6363115_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 1.889e-259 816.0
PYH1_k127_6363115_20 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 290.0
PYH1_k127_6363115_21 Glutathione S-Transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000001068 269.0
PYH1_k127_6363115_22 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000197 229.0
PYH1_k127_6363115_23 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000128 209.0
PYH1_k127_6363115_24 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000001986 217.0
PYH1_k127_6363115_25 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000001848 186.0
PYH1_k127_6363115_26 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000007683 171.0
PYH1_k127_6363115_27 NIPSNAP - - - 0.000000000000000000000000000000000000000004253 157.0
PYH1_k127_6363115_28 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000001018 158.0
PYH1_k127_6363115_29 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000008014 148.0
PYH1_k127_6363115_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.488e-223 726.0
PYH1_k127_6363115_30 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000002513 154.0
PYH1_k127_6363115_31 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000008463 115.0
PYH1_k127_6363115_4 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 4.531e-207 650.0
PYH1_k127_6363115_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.022e-206 665.0
PYH1_k127_6363115_6 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 533.0
PYH1_k127_6363115_7 glycolate oxidase subunit GlcD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 511.0
PYH1_k127_6363115_8 ABC transporter K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 411.0
PYH1_k127_6363115_9 Zinc-binding dehydrogenase K12957,K13953,K19961 - 1.1.1.1,1.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 421.0
PYH1_k127_6368546_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 539.0
PYH1_k127_6368546_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 340.0
PYH1_k127_6368546_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 340.0
PYH1_k127_6370373_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.28e-283 886.0
PYH1_k127_6370373_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.32e-229 717.0
PYH1_k127_6370373_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000005197 103.0
PYH1_k127_6370373_11 TIGRFAM type I secretion membrane fusion protein, HlyD - - - 0.0000000000004986 81.0
PYH1_k127_6370373_12 Histidine kinase K14986 - 2.7.13.3 0.0000009946 61.0
PYH1_k127_6370373_2 (ABC) transporter K11004,K13409 - - 4.759e-227 723.0
PYH1_k127_6370373_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 559.0
PYH1_k127_6370373_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 556.0
PYH1_k127_6370373_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 434.0
PYH1_k127_6370373_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 420.0
PYH1_k127_6370373_7 Branched-chain amino acid ATP-binding cassette transporter K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 374.0
PYH1_k127_6370373_8 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 331.0
PYH1_k127_6370373_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
PYH1_k127_6403016_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 523.0
PYH1_k127_6403016_1 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000002108 113.0
PYH1_k127_6409310_0 Selenium-binding protein K17285 - - 5.204e-222 693.0
PYH1_k127_6409310_1 Amidase K02433 - 6.3.5.6,6.3.5.7 8.791e-202 642.0
PYH1_k127_6409310_2 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 580.0
PYH1_k127_6409310_3 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 462.0
PYH1_k127_6409310_4 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 457.0
PYH1_k127_6409310_5 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002932 278.0
PYH1_k127_6409310_6 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000009133 208.0
PYH1_k127_6409310_7 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000000000000000000000006963 156.0
PYH1_k127_6409310_8 EamA-like transporter family - - - 0.0000000000000000000000000000000374 136.0
PYH1_k127_6409310_9 - - - - 0.000000000000000000000000000001103 133.0
PYH1_k127_6410827_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 5.763e-274 859.0
PYH1_k127_6410827_1 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 4.174e-215 678.0
PYH1_k127_6410827_10 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 393.0
PYH1_k127_6410827_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 372.0
PYH1_k127_6410827_12 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 359.0
PYH1_k127_6410827_13 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 366.0
PYH1_k127_6410827_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 351.0
PYH1_k127_6410827_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 297.0
PYH1_k127_6410827_16 leucine import across plasma membrane K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 291.0
PYH1_k127_6410827_17 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
PYH1_k127_6410827_18 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001951 271.0
PYH1_k127_6410827_19 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001885 271.0
PYH1_k127_6410827_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.728e-213 694.0
PYH1_k127_6410827_20 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008014 285.0
PYH1_k127_6410827_21 - - - - 0.0000000000000000000000000009166 130.0
PYH1_k127_6410827_3 Carboxyl transferase domain - - - 3.967e-211 667.0
PYH1_k127_6410827_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 550.0
PYH1_k127_6410827_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 508.0
PYH1_k127_6410827_6 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 541.0
PYH1_k127_6410827_7 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 511.0
PYH1_k127_6410827_8 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 485.0
PYH1_k127_6410827_9 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 384.0
PYH1_k127_6422341_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 7.405e-245 762.0
PYH1_k127_6422341_1 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005644 282.0
PYH1_k127_6422341_2 Psort location Extracellular, score - - - 0.0000000000000000007326 90.0
PYH1_k127_6422505_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 576.0
PYH1_k127_6422505_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 407.0
PYH1_k127_6422505_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 360.0
PYH1_k127_6422505_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.00000000000001057 82.0
PYH1_k127_6422505_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0002798 43.0
PYH1_k127_6444142_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 6.67e-209 662.0
PYH1_k127_6444142_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 595.0
PYH1_k127_6444142_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000005054 160.0
PYH1_k127_6444142_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000006342 164.0
PYH1_k127_6444142_12 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000001395 118.0
PYH1_k127_6444142_2 thiolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 558.0
PYH1_k127_6444142_3 Peptidase family M28 K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 500.0
PYH1_k127_6444142_4 fad dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 463.0
PYH1_k127_6444142_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 419.0
PYH1_k127_6444142_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 339.0
PYH1_k127_6444142_7 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002098 282.0
PYH1_k127_6444142_8 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000003633 218.0
PYH1_k127_6444142_9 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000000009382 163.0
PYH1_k127_6494108_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 3.464e-277 865.0
PYH1_k127_6494108_1 Domain of unknown function (DUF3394) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 292.0
PYH1_k127_6494108_2 Zinc-binding dehydrogenase - - - 0.0001668 44.0
PYH1_k127_6553758_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 458.0
PYH1_k127_6553758_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000002822 138.0
PYH1_k127_6580838_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.403e-287 890.0
PYH1_k127_6580838_1 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 4.845e-284 888.0
PYH1_k127_6580838_10 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 388.0
PYH1_k127_6580838_11 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000003051 228.0
PYH1_k127_6580838_12 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
PYH1_k127_6580838_13 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000004305 161.0
PYH1_k127_6580838_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000001096 117.0
PYH1_k127_6580838_15 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000009105 83.0
PYH1_k127_6580838_16 low-complexity proteins - - - 0.0000000000000984 82.0
PYH1_k127_6580838_2 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 5.657e-280 872.0
PYH1_k127_6580838_3 homoserine dehydrogenase - - - 2.022e-209 659.0
PYH1_k127_6580838_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 550.0
PYH1_k127_6580838_5 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 483.0
PYH1_k127_6580838_6 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 462.0
PYH1_k127_6580838_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 437.0
PYH1_k127_6580838_8 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 431.0
PYH1_k127_6580838_9 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 441.0
PYH1_k127_6582292_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 3.352e-249 778.0
PYH1_k127_6582292_1 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001822 291.0
PYH1_k127_6582292_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000002103 144.0
PYH1_k127_6582292_3 MJ0042 family finger-like - - - 0.0000003012 61.0
PYH1_k127_6602924_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.576e-214 683.0
PYH1_k127_6602924_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 573.0
PYH1_k127_6602924_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 511.0
PYH1_k127_6602924_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 361.0
PYH1_k127_6602924_4 TIGRFAM methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000002728 256.0
PYH1_k127_6602924_5 homology - - - 0.0000000000000000000000000000000000000003919 159.0
PYH1_k127_6602924_6 Phosphotransferase System K11189 - - 0.000000000000000000000000000000004933 129.0
PYH1_k127_6602924_7 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.00000008585 54.0
PYH1_k127_6639876_0 Amidohydrolase family - - - 4.044e-232 730.0
PYH1_k127_6639876_1 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 419.0
PYH1_k127_6639876_2 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 361.0
PYH1_k127_6639876_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 357.0
PYH1_k127_6639876_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04098 - 1.13.11.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 330.0
PYH1_k127_6639876_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 296.0
PYH1_k127_6639876_6 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009521 263.0
PYH1_k127_6639876_7 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 249.0
PYH1_k127_6639876_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000003088 224.0
PYH1_k127_6639876_9 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K20023 - 4.2.1.156,4.2.1.42 0.000000000000000002506 91.0
PYH1_k127_6651152_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 563.0
PYH1_k127_6686317_0 Protein of unknown function (DUF1302) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 512.0
PYH1_k127_6686317_1 PFAM type II secretion system K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 426.0
PYH1_k127_6686317_2 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
PYH1_k127_6686317_3 Sigma factor PP2C-like phosphatases K07315,K07680 - 2.7.13.3,3.1.3.3 0.000000000000000000000000000000000000000000000000000000008539 225.0
PYH1_k127_6686317_4 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000002965 194.0
PYH1_k127_6686317_5 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000001778 150.0
PYH1_k127_6686317_6 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000000000000000009958 132.0
PYH1_k127_6686317_7 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000004461 109.0
PYH1_k127_6686317_8 - - - - 0.00000002243 65.0
PYH1_k127_6686317_9 Secretin and TonB N terminus short domain K02453 - - 0.00001202 57.0
PYH1_k127_6689727_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 5.566e-255 807.0
PYH1_k127_6689727_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 540.0
PYH1_k127_6689727_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 468.0
PYH1_k127_6689727_3 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 331.0
PYH1_k127_6689727_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
PYH1_k127_6689727_5 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000004319 180.0
PYH1_k127_6689727_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000005733 59.0
PYH1_k127_6689727_7 PFAM HD domain - - - 0.000000004091 69.0
PYH1_k127_6692183_0 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 428.0
PYH1_k127_6692183_1 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009255 275.0
PYH1_k127_6692183_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000003637 134.0
PYH1_k127_6692183_3 Acylphosphatase K01512 - 3.6.1.7 0.000000000000001349 87.0
PYH1_k127_6704318_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.535e-280 876.0
PYH1_k127_6704318_1 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 331.0
PYH1_k127_6704318_2 glycolate oxidase iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 324.0
PYH1_k127_6715192_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.707e-232 736.0
PYH1_k127_6715192_1 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 434.0
PYH1_k127_6715192_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001335 184.0
PYH1_k127_6715192_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000003475 90.0
PYH1_k127_6715192_4 - - - - 0.00000000000000004103 81.0
PYH1_k127_6726966_0 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 469.0
PYH1_k127_6726966_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 397.0
PYH1_k127_6726966_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000003825 136.0
PYH1_k127_6726966_3 Thioesterase superfamily - - - 0.000000000000000000000000000000007673 137.0
PYH1_k127_6737389_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1115.0
PYH1_k127_6737389_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 8.2e-321 1003.0
PYH1_k127_6737389_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 377.0
PYH1_k127_6737389_11 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 398.0
PYH1_k127_6737389_12 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 379.0
PYH1_k127_6737389_13 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 362.0
PYH1_k127_6737389_14 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
PYH1_k127_6737389_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
PYH1_k127_6737389_16 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 342.0
PYH1_k127_6737389_17 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 329.0
PYH1_k127_6737389_18 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002943 274.0
PYH1_k127_6737389_19 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001381 269.0
PYH1_k127_6737389_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 8.768e-296 925.0
PYH1_k127_6737389_20 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003073 268.0
PYH1_k127_6737389_21 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000001955 229.0
PYH1_k127_6737389_22 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
PYH1_k127_6737389_23 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000202 211.0
PYH1_k127_6737389_24 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000008496 218.0
PYH1_k127_6737389_25 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000004671 198.0
PYH1_k127_6737389_26 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000003223 191.0
PYH1_k127_6737389_27 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000003928 183.0
PYH1_k127_6737389_28 Oligoketide cyclase lipid transport protein - - - 0.00000000000000000000000000000000000009867 146.0
PYH1_k127_6737389_29 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000001032 53.0
PYH1_k127_6737389_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 7.096e-242 765.0
PYH1_k127_6737389_4 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 482.0
PYH1_k127_6737389_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 475.0
PYH1_k127_6737389_6 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 434.0
PYH1_k127_6737389_7 Methyl-transferase K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 415.0
PYH1_k127_6737389_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 418.0
PYH1_k127_6737389_9 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 393.0
PYH1_k127_6739254_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000003071 180.0
PYH1_k127_6743756_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
PYH1_k127_6743756_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 505.0
PYH1_k127_6743756_2 ABC transporter K01990,K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007575 276.0
PYH1_k127_6743756_3 PFAM ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008656 263.0
PYH1_k127_6743756_4 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000004434 207.0
PYH1_k127_6743756_5 methyltransferase activity K00563,K13307,K13330,K15256 - 2.1.1.187,2.1.1.235,2.1.1.324 0.0000000000000000000000000000000000000000000000000000006237 201.0
PYH1_k127_6743756_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000001275 162.0
PYH1_k127_6743756_7 Methyltransferase FkbM domain - - - 0.0000000462 64.0
PYH1_k127_6745404_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 1.276e-270 847.0
PYH1_k127_6745404_1 Thiolase, C-terminal domain - - - 6.944e-197 622.0
PYH1_k127_6745404_2 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 598.0
PYH1_k127_6745404_3 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 505.0
PYH1_k127_6745404_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000002542 249.0
PYH1_k127_6745404_5 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000009068 209.0
PYH1_k127_6745404_6 GntR family - - - 0.00000000000000001593 83.0
PYH1_k127_674926_0 AMP-binding enzyme K01895 - 6.2.1.1 5.036e-237 751.0
PYH1_k127_674926_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.252e-218 688.0
PYH1_k127_674926_2 Ammonium Transporter Family K03320,K06580 - - 1.136e-208 654.0
PYH1_k127_674926_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 432.0
PYH1_k127_674926_4 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
PYH1_k127_674926_5 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000001836 219.0
PYH1_k127_674926_6 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000003601 209.0
PYH1_k127_6784434_0 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 489.0
PYH1_k127_6784434_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 426.0
PYH1_k127_6784434_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 359.0
PYH1_k127_6784434_3 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000006233 231.0
PYH1_k127_6784434_4 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000005202 211.0
PYH1_k127_6784434_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000001873 110.0
PYH1_k127_6786507_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 565.0
PYH1_k127_6786507_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 434.0
PYH1_k127_6786507_2 PFAM Nucleotidyl transferase K00966,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 0.0000000000002421 81.0
PYH1_k127_6805620_0 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 345.0
PYH1_k127_6830699_0 AAA domain - - - 3.507e-263 835.0
PYH1_k127_6830699_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 560.0
PYH1_k127_6830699_2 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000004816 194.0
PYH1_k127_6830699_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000003078 149.0
PYH1_k127_6830699_4 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000008248 75.0
PYH1_k127_6830699_5 Universal stress protein family - - - 0.00000000000002914 86.0
PYH1_k127_688893_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 536.0
PYH1_k127_688893_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 484.0
PYH1_k127_688893_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 427.0
PYH1_k127_688893_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000004897 83.0
PYH1_k127_6893773_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 440.0
PYH1_k127_6893773_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000007373 139.0
PYH1_k127_6894821_0 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 348.0
PYH1_k127_6894821_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 293.0
PYH1_k127_6894821_2 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000119 148.0
PYH1_k127_6894821_3 Protein of unknown function (DUF2721) - - - 0.000000000000000000001184 108.0
PYH1_k127_6894821_4 Domain of unknown function (DUF4340) - - - 0.000000000000003198 91.0
PYH1_k127_6903896_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 1.189e-223 708.0
PYH1_k127_6903896_1 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 433.0
PYH1_k127_6903896_2 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 376.0
PYH1_k127_6903896_3 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000004802 203.0
PYH1_k127_691955_0 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 484.0
PYH1_k127_691955_1 N-terminal TM domain of oligopeptide transport permease C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 435.0
PYH1_k127_691955_2 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000001185 123.0
PYH1_k127_6936477_0 radical SAM protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 609.0
PYH1_k127_6936477_1 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 335.0
PYH1_k127_6936477_2 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004511 283.0
PYH1_k127_6936477_3 cytochrome d1 heme region K19345 - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 232.0
PYH1_k127_6936477_4 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000000004816 203.0
PYH1_k127_6936477_5 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000005921 179.0
PYH1_k127_6936477_6 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000005351 138.0
PYH1_k127_694022_0 Sulfatase K01130 - 3.1.6.1 9.384e-272 846.0
PYH1_k127_694022_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.781e-266 827.0
PYH1_k127_694022_10 cysteine dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
PYH1_k127_694022_11 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002298 257.0
PYH1_k127_694022_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000002318 236.0
PYH1_k127_694022_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000005831 231.0
PYH1_k127_694022_14 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000007603 199.0
PYH1_k127_694022_15 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000001747 201.0
PYH1_k127_694022_16 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000001112 184.0
PYH1_k127_694022_17 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000005081 161.0
PYH1_k127_694022_18 Universal stress protein - - - 0.00000000000000000000000000000000000001768 148.0
PYH1_k127_694022_19 protein conserved in bacteria - - - 0.000000000000000000000002697 109.0
PYH1_k127_694022_2 enoyl-CoA hydratase K15513 - 4.1.2.44 1.607e-247 788.0
PYH1_k127_694022_20 GYD domain - - - 0.00000000000000001632 83.0
PYH1_k127_694022_3 Poly-beta-hydroxybutyrate K03821 - - 1.304e-243 765.0
PYH1_k127_694022_4 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.02e-242 757.0
PYH1_k127_694022_5 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.841e-226 711.0
PYH1_k127_694022_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 480.0
PYH1_k127_694022_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 469.0
PYH1_k127_694022_8 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 443.0
PYH1_k127_694022_9 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 258.0
PYH1_k127_6950664_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 2.796e-234 733.0
PYH1_k127_6950664_1 of the major facilitator superfamily K07552 - - 0.0000000000000002557 82.0
PYH1_k127_698276_0 Diguanylate cyclase - - - 2.627e-201 670.0
PYH1_k127_698276_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 616.0
PYH1_k127_698276_2 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 461.0
PYH1_k127_698276_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 301.0
PYH1_k127_698276_4 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002574 299.0
PYH1_k127_698276_5 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP K08682 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576 3.1.4.14 0.00000000000000000000000000000000000000000000000000000001143 203.0
PYH1_k127_698276_6 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000001253 203.0
PYH1_k127_698276_7 Cupin 2, conserved barrel - - - 0.000000000000000000000001849 109.0
PYH1_k127_6990259_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 528.0
PYH1_k127_6990259_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 482.0
PYH1_k127_6990259_2 Zinc-finger domain - - - 0.0000000000000000001164 101.0
PYH1_k127_7003139_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1310.0
PYH1_k127_7003139_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 530.0
PYH1_k127_7003139_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 517.0
PYH1_k127_7003139_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 471.0
PYH1_k127_7003139_4 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 397.0
PYH1_k127_7003139_5 Belongs to the ompA family K03286 - - 0.0000000004938 63.0
PYH1_k127_7003139_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0003079 53.0
PYH1_k127_7003264_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.918e-205 649.0
PYH1_k127_7003264_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 3.578e-197 624.0
PYH1_k127_7003264_10 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000377 198.0
PYH1_k127_7003264_11 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000003642 199.0
PYH1_k127_7003264_12 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000000000000000000000000008645 203.0
PYH1_k127_7003264_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000004986 153.0
PYH1_k127_7003264_2 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 475.0
PYH1_k127_7003264_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 447.0
PYH1_k127_7003264_4 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 374.0
PYH1_k127_7003264_5 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 344.0
PYH1_k127_7003264_6 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 301.0
PYH1_k127_7003264_7 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 289.0
PYH1_k127_7003264_8 Pyrimidine 5''-nucleotidase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
PYH1_k127_7003264_9 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000003411 210.0
PYH1_k127_7018061_0 D-galactarate dehydratase K16846,K16850 - 4.2.1.7,4.4.1.24 6.077e-213 670.0
PYH1_k127_7018061_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 529.0
PYH1_k127_7018061_2 Aconitase C-terminal domain K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 419.0
PYH1_k127_7018061_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - 0.000000000000000000000000000000000000000000000000000000000001034 216.0
PYH1_k127_7018061_4 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000001327 233.0
PYH1_k127_7018061_5 SAF K16845 - 4.4.1.24 0.00000000000000000000000000000000000000001447 154.0
PYH1_k127_7024712_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 588.0
PYH1_k127_7024712_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001932 287.0
PYH1_k127_7046291_0 Acyl-CoA synthetase (NDP forming) K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 426.0
PYH1_k127_7075331_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 1.812e-206 646.0
PYH1_k127_7075331_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 537.0
PYH1_k127_7075331_2 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 0.0000000000000000000000007016 105.0
PYH1_k127_7084240_0 Neisseria PilC beta-propeller domain K02674 - - 2.836e-210 704.0
PYH1_k127_7084240_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 459.0
PYH1_k127_7084240_10 Pilus assembly protein PilX - - - 0.0000000000000000000000000000405 124.0
PYH1_k127_7084240_11 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000001106 112.0
PYH1_k127_7084240_12 Type II transport protein GspH K08084 - - 0.000000000000000000000001058 111.0
PYH1_k127_7084240_13 Thioesterase superfamily - - - 0.000000001039 66.0
PYH1_k127_7084240_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 400.0
PYH1_k127_7084240_3 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 323.0
PYH1_k127_7084240_4 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 315.0
PYH1_k127_7084240_5 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 306.0
PYH1_k127_7084240_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000003392 252.0
PYH1_k127_7084240_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000005111 241.0
PYH1_k127_7084240_8 type 4 fimbrial biogenesis K02672 - - 0.000000000000000000000000000000000000000000000000000000000000000002871 238.0
PYH1_k127_7084240_9 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000000000000000008972 157.0
PYH1_k127_711184_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 2.872e-296 917.0
PYH1_k127_711184_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 3.989e-263 837.0
PYH1_k127_711184_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 309.0
PYH1_k127_711184_11 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000266 286.0
PYH1_k127_711184_12 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000154 239.0
PYH1_k127_711184_13 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000009513 213.0
PYH1_k127_711184_14 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000003459 213.0
PYH1_k127_711184_15 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000002874 166.0
PYH1_k127_711184_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000003515 107.0
PYH1_k127_711184_17 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000006677 52.0
PYH1_k127_711184_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 621.0
PYH1_k127_711184_3 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 532.0
PYH1_k127_711184_4 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 467.0
PYH1_k127_711184_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 435.0
PYH1_k127_711184_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 420.0
PYH1_k127_711184_7 phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 415.0
PYH1_k127_711184_8 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 376.0
PYH1_k127_711184_9 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
PYH1_k127_715741_0 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 391.0
PYH1_k127_715741_1 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 396.0
PYH1_k127_715741_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000003135 73.0
PYH1_k127_7209002_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.755e-215 688.0
PYH1_k127_7209002_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 399.0
PYH1_k127_7209002_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 395.0
PYH1_k127_7209002_3 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000000001522 86.0
PYH1_k127_7238971_0 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 493.0
PYH1_k127_7238971_1 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000001267 179.0
PYH1_k127_7257138_0 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 415.0
PYH1_k127_7257138_1 Protein of unknown function (DUF3467) - - - 0.0001534 49.0
PYH1_k127_7261664_0 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 541.0
PYH1_k127_7261664_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 514.0
PYH1_k127_7261664_10 PFAM DNA photolyase FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000004275 108.0
PYH1_k127_7261664_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 492.0
PYH1_k127_7261664_3 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 365.0
PYH1_k127_7261664_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 310.0
PYH1_k127_7261664_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009677 274.0
PYH1_k127_7261664_6 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000002764 200.0
PYH1_k127_7261664_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000003484 143.0
PYH1_k127_7261664_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000006212 120.0
PYH1_k127_7261664_9 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000007249 119.0
PYH1_k127_7267196_0 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 1.794e-224 723.0
PYH1_k127_7267196_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 595.0
PYH1_k127_7267196_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 572.0
PYH1_k127_7267196_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 542.0
PYH1_k127_7267196_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 432.0
PYH1_k127_7267196_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 360.0
PYH1_k127_7267196_6 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 316.0
PYH1_k127_7267196_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 304.0
PYH1_k127_7285759_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1067.0
PYH1_k127_7285759_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 587.0
PYH1_k127_7285759_10 Universal stress protein - - - 0.00000000000000000000000002762 114.0
PYH1_k127_7285759_11 - - - - 0.00001893 50.0
PYH1_k127_7285759_2 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 537.0
PYH1_k127_7285759_3 Aminotransferase K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 527.0
PYH1_k127_7285759_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 511.0
PYH1_k127_7285759_5 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 447.0
PYH1_k127_7285759_6 Formate/nitrite transporter K06212,K21993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 405.0
PYH1_k127_7285759_7 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 376.0
PYH1_k127_7285759_8 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000002626 206.0
PYH1_k127_7285759_9 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000001213 184.0
PYH1_k127_7291177_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 9.698e-257 811.0
PYH1_k127_7291177_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.891e-253 787.0
PYH1_k127_7291177_10 Thioredoxin-like - - - 0.000000000000000000000000000155 129.0
PYH1_k127_7291177_11 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0000000000000000000001007 113.0
PYH1_k127_7291177_12 Flavinator of succinate dehydrogenase K09159 - - 0.00000008603 61.0
PYH1_k127_7291177_13 Protein of unknown function (DUF3460) - - - 0.000004461 59.0
PYH1_k127_7291177_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.072e-226 708.0
PYH1_k127_7291177_3 Belongs to the citrate synthase family K01659 - 2.3.3.5 4.201e-199 640.0
PYH1_k127_7291177_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 482.0
PYH1_k127_7291177_5 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 442.0
PYH1_k127_7291177_6 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 435.0
PYH1_k127_7291177_7 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 426.0
PYH1_k127_7291177_8 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000003217 147.0
PYH1_k127_7291177_9 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000005379 148.0
PYH1_k127_7318071_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 404.0
PYH1_k127_7318071_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 357.0
PYH1_k127_7318071_2 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
PYH1_k127_7318071_3 signal sequence binding - - - 0.000000000000000000000000000000000000000000000002286 179.0
PYH1_k127_7318071_4 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000001679 154.0
PYH1_k127_7318071_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000001438 141.0
PYH1_k127_7351071_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 9.256e-241 748.0
PYH1_k127_7351071_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.221e-214 677.0
PYH1_k127_7351071_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003608 241.0
PYH1_k127_7351071_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000004747 195.0
PYH1_k127_7351071_4 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001018 74.0
PYH1_k127_7351764_0 Branched-chain amino acid transport system / permease component K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 537.0
PYH1_k127_7351764_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 491.0
PYH1_k127_7351764_2 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 408.0
PYH1_k127_7351764_3 ABC transporter, ATP-binding protein K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 377.0
PYH1_k127_7351764_4 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000002008 99.0
PYH1_k127_7352192_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1274.0
PYH1_k127_7352192_1 AcrB/AcrD/AcrF family - - - 0.0 1242.0
PYH1_k127_7352192_10 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 382.0
PYH1_k127_7352192_11 PFAM molybdopterin dehydrogenase, FAD-binding K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 317.0
PYH1_k127_7352192_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 321.0
PYH1_k127_7352192_13 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 317.0
PYH1_k127_7352192_14 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 295.0
PYH1_k127_7352192_15 molybdenum cofactor K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006529 274.0
PYH1_k127_7352192_16 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 265.0
PYH1_k127_7352192_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005668 260.0
PYH1_k127_7352192_18 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000783 247.0
PYH1_k127_7352192_19 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001596 237.0
PYH1_k127_7352192_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1207.0
PYH1_k127_7352192_20 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000006643 226.0
PYH1_k127_7352192_21 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000002762 236.0
PYH1_k127_7352192_22 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000004071 199.0
PYH1_k127_7352192_23 Molybdopterin-guanine dinucleotide biosynthesis protein MobA K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000004741 192.0
PYH1_k127_7352192_24 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000000000000000002771 175.0
PYH1_k127_7352192_25 carbon monoxide dehydrogenase K09386 - - 0.000000000000000000000000000000000000000001511 177.0
PYH1_k127_7352192_26 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000669 161.0
PYH1_k127_7352192_27 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000006968 115.0
PYH1_k127_7352192_28 Lipocalin-like domain - - - 0.00000000000002654 79.0
PYH1_k127_7352192_3 peptidase U62, modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 524.0
PYH1_k127_7352192_30 Adenylate cyclase K01768 - 4.6.1.1 0.00000001109 67.0
PYH1_k127_7352192_31 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000001733 57.0
PYH1_k127_7352192_4 response regulator K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 531.0
PYH1_k127_7352192_5 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 445.0
PYH1_k127_7352192_6 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 445.0
PYH1_k127_7352192_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 439.0
PYH1_k127_7352192_8 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 423.0
PYH1_k127_7352192_9 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 428.0
PYH1_k127_7358432_0 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 473.0
PYH1_k127_7358432_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000001426 224.0
PYH1_k127_7358432_2 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000129 184.0
PYH1_k127_7358432_3 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000003639 84.0
PYH1_k127_7362416_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 8.351e-232 734.0
PYH1_k127_7362416_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 1.942e-231 738.0
PYH1_k127_7362416_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 368.0
PYH1_k127_7362416_3 NMT1-like family - - - 0.00000005275 54.0
PYH1_k127_7451838_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 3.491e-316 983.0
PYH1_k127_7451838_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 602.0
PYH1_k127_7451838_2 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 499.0
PYH1_k127_7451838_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 343.0
PYH1_k127_7451838_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 323.0
PYH1_k127_7451838_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005752 247.0
PYH1_k127_7451838_6 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000001184 223.0
PYH1_k127_7451838_7 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000005799 195.0
PYH1_k127_7451838_8 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000239 126.0
PYH1_k127_7473796_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 1.774e-266 835.0
PYH1_k127_7473796_1 Isocitrate lyase K01637 - 4.1.3.1 3.108e-225 705.0
PYH1_k127_7473796_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 7.45e-221 702.0
PYH1_k127_7473796_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 482.0
PYH1_k127_7473796_4 - - - - 0.00000000000000000000000000002302 127.0
PYH1_k127_7473796_5 Belongs to the UPF0235 family K09131 - - 0.0001411 45.0
PYH1_k127_7483522_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 1.008e-250 782.0
PYH1_k127_7494230_0 Protein of unknown function - - - 8.601e-200 654.0
PYH1_k127_7494230_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 407.0
PYH1_k127_7515125_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 432.0
PYH1_k127_7515125_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 320.0
PYH1_k127_7515125_2 phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009898 280.0
PYH1_k127_7515125_3 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000005844 194.0
PYH1_k127_7515125_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000004321 168.0
PYH1_k127_7515125_5 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000169 154.0
PYH1_k127_7515125_6 Chromate transporter K07240 - - 0.000000000000000000000000000000000000004817 164.0
PYH1_k127_7515125_7 overlaps another CDS with the same product name K07240 - - 0.0000000000000000000000000000000000001933 147.0
PYH1_k127_7543614_0 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 4.387e-194 615.0
PYH1_k127_7543614_1 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 354.0
PYH1_k127_7543614_2 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000004331 224.0
PYH1_k127_7543614_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000005608 85.0
PYH1_k127_7543614_4 mechanosensitive ion channel K22044 - - 0.0002885 53.0
PYH1_k127_7553280_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 370.0
PYH1_k127_7553280_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001712 271.0
PYH1_k127_7553280_2 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008139 262.0
PYH1_k127_7553280_3 Transcriptional regulator, Crp Fnr family K21563 - - 0.0000000000000732 81.0
PYH1_k127_7553280_4 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000003433 63.0
PYH1_k127_7553514_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 341.0
PYH1_k127_7553514_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 318.0
PYH1_k127_7553514_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001924 246.0
PYH1_k127_7553514_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
PYH1_k127_7553514_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000000000000000000002152 160.0
PYH1_k127_7553514_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000007891 79.0
PYH1_k127_7553514_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000002945 68.0
PYH1_k127_7571653_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 576.0
PYH1_k127_7571653_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 440.0
PYH1_k127_7571653_2 Tyrosine recombinase xerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 369.0
PYH1_k127_7571653_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 292.0
PYH1_k127_7571653_4 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
PYH1_k127_7571653_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000001178 186.0
PYH1_k127_7571653_6 YqeY-like protein K09117 - - 0.000000000000000000000000000000000000000000000001154 182.0
PYH1_k127_7571653_7 Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000001047 147.0
PYH1_k127_7571653_8 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000005073 124.0
PYH1_k127_7571653_9 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000006415 123.0
PYH1_k127_7582376_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.443e-235 737.0
PYH1_k127_7582376_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.371e-199 627.0
PYH1_k127_7582376_2 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 481.0
PYH1_k127_7582376_3 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 467.0
PYH1_k127_7582376_4 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 472.0
PYH1_k127_7582376_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 303.0
PYH1_k127_7582376_6 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 312.0
PYH1_k127_7582376_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000006388 253.0
PYH1_k127_7582376_8 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000003862 250.0
PYH1_k127_7582376_9 Tetratricopeptide repeat - - - 0.0000000000000000000002658 113.0
PYH1_k127_759094_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 457.0
PYH1_k127_759094_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 384.0
PYH1_k127_7600144_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1062.0
PYH1_k127_7600144_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 541.0
PYH1_k127_7600144_10 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000009246 173.0
PYH1_k127_7600144_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000004925 135.0
PYH1_k127_7600144_2 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 522.0
PYH1_k127_7600144_3 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 487.0
PYH1_k127_7600144_4 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 462.0
PYH1_k127_7600144_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 419.0
PYH1_k127_7600144_6 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 389.0
PYH1_k127_7600144_7 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004756 297.0
PYH1_k127_7600144_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000005462 233.0
PYH1_k127_7600144_9 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000001508 205.0
PYH1_k127_7613833_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 348.0
PYH1_k127_7613833_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 334.0
PYH1_k127_7613833_2 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
PYH1_k127_7613833_3 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000001753 169.0
PYH1_k127_7613833_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000001798 100.0
PYH1_k127_7613833_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000001568 98.0
PYH1_k127_7622075_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1054.0
PYH1_k127_7622075_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000001135 212.0
PYH1_k127_7629220_0 PFAM type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
PYH1_k127_7629220_1 Tetratricopeptide repeat - - - 0.000000001795 67.0
PYH1_k127_7631543_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4e-323 1009.0
PYH1_k127_7631543_1 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 7.674e-277 876.0
PYH1_k127_7631543_10 - - - - 0.0001975 48.0
PYH1_k127_7631543_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 345.0
PYH1_k127_7631543_3 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 327.0
PYH1_k127_7631543_4 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000022 284.0
PYH1_k127_7631543_5 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001127 263.0
PYH1_k127_7631543_6 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006932 222.0
PYH1_k127_7631543_7 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000005635 163.0
PYH1_k127_7631543_8 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000001052 78.0
PYH1_k127_7631543_9 Domain of unknown function (DUF4136) - - - 0.0000002883 58.0
PYH1_k127_7632260_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 467.0
PYH1_k127_7632260_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 378.0
PYH1_k127_7632260_2 Pfam Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000008318 259.0
PYH1_k127_7632260_3 PFAM conserved - - - 0.00000000000000000000000000000000002538 136.0
PYH1_k127_7641038_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1291.0
PYH1_k127_7641038_1 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 467.0
PYH1_k127_7641038_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000006996 174.0
PYH1_k127_7641038_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000001099 145.0
PYH1_k127_7641038_4 - - - - 0.0004021 47.0
PYH1_k127_7676266_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.717e-242 759.0
PYH1_k127_7676266_1 Protein of unknown function (DUF1254) - - - 1.42e-198 620.0
PYH1_k127_7676266_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006572 292.0
PYH1_k127_7676266_3 - - - - 0.0000000000000000000008835 102.0
PYH1_k127_7676932_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 483.0
PYH1_k127_7676932_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 435.0
PYH1_k127_7676932_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000003065 62.0
PYH1_k127_7686707_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 420.0
PYH1_k127_7686707_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 404.0
PYH1_k127_7686707_10 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000000000000000274 201.0
PYH1_k127_7686707_11 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000484 117.0
PYH1_k127_7686707_12 STAS domain K07122 - - 0.00000000000001631 77.0
PYH1_k127_7686707_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 375.0
PYH1_k127_7686707_3 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 377.0
PYH1_k127_7686707_4 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 356.0
PYH1_k127_7686707_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 335.0
PYH1_k127_7686707_6 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001123 289.0
PYH1_k127_7686707_7 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008419 274.0
PYH1_k127_7686707_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
PYH1_k127_7686707_9 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000006199 223.0
PYH1_k127_7690192_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.808e-303 935.0
PYH1_k127_7690192_1 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 2.124e-198 625.0
PYH1_k127_7690192_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K18356 - 1.2.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 553.0
PYH1_k127_7690192_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K18357 - 1.2.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003253 278.0
PYH1_k127_7690192_4 Rubrerythrin - - - 0.00001018 56.0
PYH1_k127_7690192_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0002103 45.0
PYH1_k127_7701833_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 1.4e-219 695.0
PYH1_k127_7701833_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 310.0
PYH1_k127_7713666_0 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 447.0
PYH1_k127_7713666_1 KR domain - - - 0.0000000002753 61.0
PYH1_k127_7723334_0 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000008239 203.0
PYH1_k127_7723334_1 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000606 160.0
PYH1_k127_7723334_2 CRP FNR family K21563 - - 0.00000000000000000000000000000000000000105 156.0
PYH1_k127_7723334_3 Universal stress protein - - - 0.00000000000000000000000000000000005898 139.0
PYH1_k127_7723334_4 Universal stress protein - - - 0.00000000000000000000000000000000023 139.0
PYH1_k127_7723334_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000001167 61.0
PYH1_k127_7736429_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.101e-253 795.0
PYH1_k127_7736429_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 533.0
PYH1_k127_7736429_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000002367 147.0
PYH1_k127_7736429_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000003394 126.0
PYH1_k127_7736429_12 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000003787 112.0
PYH1_k127_7736429_13 - - - - 0.00000000000000000000000002582 114.0
PYH1_k127_7736429_14 - - - - 0.0000000000000000000001149 102.0
PYH1_k127_7736429_15 - K06950 - - 0.0000000001566 66.0
PYH1_k127_7736429_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 421.0
PYH1_k127_7736429_3 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 398.0
PYH1_k127_7736429_4 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 323.0
PYH1_k127_7736429_5 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000004334 269.0
PYH1_k127_7736429_6 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000003372 234.0
PYH1_k127_7736429_7 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.0000000000000000000000000000000000000004899 170.0
PYH1_k127_7736429_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000001368 149.0
PYH1_k127_7736429_9 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000004214 149.0
PYH1_k127_7740567_0 Rod shape-determining protein MreB K03569 - - 3.38e-201 630.0
PYH1_k127_7740567_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000006323 130.0
PYH1_k127_7740567_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000005928 105.0
PYH1_k127_7740567_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000003501 89.0
PYH1_k127_7742978_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1388.0
PYH1_k127_7742978_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 7.872e-305 947.0
PYH1_k127_7742978_10 Bacterial extracellular solute-binding protein K02027 - - 5.248e-214 672.0
PYH1_k127_7742978_11 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 3.774e-206 657.0
PYH1_k127_7742978_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 2.44e-198 631.0
PYH1_k127_7742978_13 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 601.0
PYH1_k127_7742978_14 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 534.0
PYH1_k127_7742978_15 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 538.0
PYH1_k127_7742978_16 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 518.0
PYH1_k127_7742978_17 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 525.0
PYH1_k127_7742978_18 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 494.0
PYH1_k127_7742978_19 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 494.0
PYH1_k127_7742978_2 Dehydratase family K13875 - 4.2.1.25 8.794e-305 943.0
PYH1_k127_7742978_20 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 497.0
PYH1_k127_7742978_21 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 484.0
PYH1_k127_7742978_22 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 487.0
PYH1_k127_7742978_23 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 486.0
PYH1_k127_7742978_24 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 436.0
PYH1_k127_7742978_25 carbohydrate phosphatase activity K01086 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 432.0
PYH1_k127_7742978_26 PFAM fumarylacetoacetate (FAA) hydrolase K18336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 417.0
PYH1_k127_7742978_27 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 409.0
PYH1_k127_7742978_28 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 381.0
PYH1_k127_7742978_29 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 362.0
PYH1_k127_7742978_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.976e-300 932.0
PYH1_k127_7742978_30 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 356.0
PYH1_k127_7742978_31 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 348.0
PYH1_k127_7742978_32 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 324.0
PYH1_k127_7742978_33 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 334.0
PYH1_k127_7742978_34 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 299.0
PYH1_k127_7742978_35 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
PYH1_k127_7742978_36 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 295.0
PYH1_k127_7742978_37 subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000001034 231.0
PYH1_k127_7742978_38 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000004124 232.0
PYH1_k127_7742978_39 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000005594 227.0
PYH1_k127_7742978_4 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.579e-292 901.0
PYH1_k127_7742978_40 Tripartite ATP-independent periplasmic transporter - - - 0.0000000000000000000000000000000000000000000000000000000000001074 220.0
PYH1_k127_7742978_41 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000002476 203.0
PYH1_k127_7742978_42 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000002048 188.0
PYH1_k127_7742978_43 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000002607 167.0
PYH1_k127_7742978_44 glycosyl transferase K12983,K12988,K19354 - - 0.000000000000000000000000000000000000000000008236 177.0
PYH1_k127_7742978_45 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000005412 156.0
PYH1_k127_7742978_46 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000007677 160.0
PYH1_k127_7742978_47 AraC-like ligand binding domain - - - 0.00000000000000000000000000000004042 138.0
PYH1_k127_7742978_48 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000001946 121.0
PYH1_k127_7742978_49 Domain of unknown function (DUF4124) - - - 0.000000000000000000003074 100.0
PYH1_k127_7742978_5 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.814e-283 874.0
PYH1_k127_7742978_50 protein ubiquitination - - - 0.00002201 54.0
PYH1_k127_7742978_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 9.212e-258 827.0
PYH1_k127_7742978_7 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.39e-244 761.0
PYH1_k127_7742978_8 Belongs to the malate synthase family K01638 - 2.3.3.9 5.891e-241 755.0
PYH1_k127_7742978_9 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 1.218e-228 717.0
PYH1_k127_7743697_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.932e-246 770.0
PYH1_k127_7743697_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 4.194e-228 713.0
PYH1_k127_7743697_10 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 353.0
PYH1_k127_7743697_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000002033 257.0
PYH1_k127_7743697_12 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000004123 241.0
PYH1_k127_7743697_13 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000133 146.0
PYH1_k127_7743697_14 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000001003 134.0
PYH1_k127_7743697_15 Protein of unknown function (DUF3306) - - - 0.0000000000000000000002721 108.0
PYH1_k127_7743697_2 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 601.0
PYH1_k127_7743697_3 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 516.0
PYH1_k127_7743697_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 486.0
PYH1_k127_7743697_5 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 471.0
PYH1_k127_7743697_6 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 432.0
PYH1_k127_7743697_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 385.0
PYH1_k127_7743697_8 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 360.0
PYH1_k127_7743697_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 352.0
PYH1_k127_7750704_0 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 3.016e-252 787.0
PYH1_k127_7750704_1 Proton-conducting membrane transporter - - - 2.202e-227 722.0
PYH1_k127_7750704_2 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 448.0
PYH1_k127_7750704_3 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 299.0
PYH1_k127_7751591_0 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 467.0
PYH1_k127_7751591_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000001902 245.0
PYH1_k127_7751591_2 YgbB family K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000007255 222.0
PYH1_k127_7751591_3 transcriptional regulator K07734 - - 0.0000000000000000000000000000000000000000000000001439 189.0
PYH1_k127_7751591_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000008488 123.0
PYH1_k127_7754633_0 Belongs to the glutamate synthase family - - - 4.012e-248 774.0
PYH1_k127_7754633_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 6.568e-206 675.0
PYH1_k127_7754633_2 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 584.0
PYH1_k127_7754633_3 Fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 468.0
PYH1_k127_7754633_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 452.0
PYH1_k127_7754633_5 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 337.0
PYH1_k127_7754633_6 transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000000002064 199.0
PYH1_k127_7754633_7 VIT family - - - 0.0000000000000006551 82.0
PYH1_k127_7759365_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.2e-213 677.0
PYH1_k127_7759365_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 622.0
PYH1_k127_7759365_10 GGDEF domain K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000005253 230.0
PYH1_k127_7759365_11 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000006494 188.0
PYH1_k127_7759365_12 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000001267 198.0
PYH1_k127_7759365_13 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000003111 134.0
PYH1_k127_7759365_14 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000000000000000000000001761 132.0
PYH1_k127_7759365_15 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000001606 120.0
PYH1_k127_7759365_16 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000001608 96.0
PYH1_k127_7759365_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000101 65.0
PYH1_k127_7759365_18 Bacterial extracellular solute-binding protein K02020 - - 0.000000004317 61.0
PYH1_k127_7759365_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 556.0
PYH1_k127_7759365_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 505.0
PYH1_k127_7759365_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 451.0
PYH1_k127_7759365_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 432.0
PYH1_k127_7759365_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 406.0
PYH1_k127_7759365_7 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 302.0
PYH1_k127_7759365_8 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008698 269.0
PYH1_k127_7759365_9 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000002237 255.0
PYH1_k127_7760522_0 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 469.0
PYH1_k127_7760522_1 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 379.0
PYH1_k127_7760522_2 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 323.0
PYH1_k127_7760522_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 314.0
PYH1_k127_7760522_4 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009914 270.0
PYH1_k127_7760522_5 Aldo keto - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007543 265.0
PYH1_k127_7770471_0 Fumarate reductase flavoprotein C-term - - - 1.809e-200 634.0
PYH1_k127_7770471_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 501.0
PYH1_k127_7770471_2 C4-dicarboxylate transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 497.0
PYH1_k127_7770471_3 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 430.0
PYH1_k127_7770471_4 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 419.0
PYH1_k127_7770471_5 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000001003 153.0
PYH1_k127_7779601_0 amino acid K11959 - - 1.539e-231 722.0
PYH1_k127_7779601_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000002111 85.0
PYH1_k127_7780229_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 1.001e-275 859.0
PYH1_k127_7780229_1 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 2.104e-202 634.0
PYH1_k127_7780229_10 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000001079 154.0
PYH1_k127_7780229_11 Rhodanese-like domain - - - 0.0000000000000000000000000000442 123.0
PYH1_k127_7780229_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 474.0
PYH1_k127_7780229_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 415.0
PYH1_k127_7780229_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 361.0
PYH1_k127_7780229_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000267 277.0
PYH1_k127_7780229_6 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000009908 201.0
PYH1_k127_7780229_7 Thioesterase K07107,K12500 - - 0.00000000000000000000000000000000000000000000000004334 198.0
PYH1_k127_7780229_8 cell division protein - - - 0.00000000000000000000000000000000000000000000005606 177.0
PYH1_k127_7780229_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000002372 151.0
PYH1_k127_7786153_0 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 449.0
PYH1_k127_7786153_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002027 270.0
PYH1_k127_7786153_2 phosphate-selective porin O and P - - - 0.0000924 48.0
PYH1_k127_779050_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 3.715e-236 739.0
PYH1_k127_779050_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 6.528e-227 709.0
PYH1_k127_779050_10 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000006705 228.0
PYH1_k127_779050_11 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000002366 207.0
PYH1_k127_779050_12 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000002325 193.0
PYH1_k127_779050_13 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000002845 181.0
PYH1_k127_779050_14 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000005427 172.0
PYH1_k127_779050_15 acetyltransferase - - - 0.00000000000000000000000000000337 129.0
PYH1_k127_779050_16 Small Multidrug Resistance protein - - - 0.000000000000000000000000004219 115.0
PYH1_k127_779050_17 Sodium Bile acid symporter family - - - 0.0000000000000004328 91.0
PYH1_k127_779050_18 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000002632 71.0
PYH1_k127_779050_19 Lipocalin-like domain - - - 0.0000000004722 64.0
PYH1_k127_779050_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.672e-208 662.0
PYH1_k127_779050_3 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 536.0
PYH1_k127_779050_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 436.0
PYH1_k127_779050_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 417.0
PYH1_k127_779050_6 Glycosyl transferase family 2 K13670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 372.0
PYH1_k127_779050_7 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 342.0
PYH1_k127_779050_8 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 306.0
PYH1_k127_779050_9 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008702 241.0
PYH1_k127_779880_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1335.0
PYH1_k127_779880_1 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 550.0
PYH1_k127_779880_2 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000001518 204.0
PYH1_k127_779880_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000003308 144.0
PYH1_k127_779880_4 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000001891 114.0
PYH1_k127_779880_5 Universal stress protein - - - 0.0000000000000000000001261 102.0
PYH1_k127_779880_6 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000001363 105.0
PYH1_k127_779880_7 Biotin-requiring enzyme - - - 0.0000000000000007623 86.0
PYH1_k127_7836442_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1245.0
PYH1_k127_7836442_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 549.0
PYH1_k127_7836442_2 [2Fe-2S] binding domain K03518,K04107 - 1.2.5.3,1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000006702 231.0
PYH1_k127_7836442_3 protein involved in response to NO K07234 - - 0.00000000000000008122 94.0
PYH1_k127_7836442_4 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.00006142 47.0
PYH1_k127_7854299_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.003e-241 754.0
PYH1_k127_7854299_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.215e-241 752.0
PYH1_k127_7854299_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 343.0
PYH1_k127_7854299_11 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 329.0
PYH1_k127_7854299_12 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 327.0
PYH1_k127_7854299_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001855 274.0
PYH1_k127_7854299_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000008457 254.0
PYH1_k127_7854299_15 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000004091 220.0
PYH1_k127_7854299_16 PFAM Colicin V production protein K03558 - - 0.00000000000000000000000000000000007792 145.0
PYH1_k127_7854299_17 Sporulation related domain K03749 - - 0.00000000000000000000000002869 115.0
PYH1_k127_7854299_18 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 0.000000000000000000000003748 104.0
PYH1_k127_7854299_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.986e-227 709.0
PYH1_k127_7854299_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 548.0
PYH1_k127_7854299_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 552.0
PYH1_k127_7854299_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 493.0
PYH1_k127_7854299_6 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 483.0
PYH1_k127_7854299_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 459.0
PYH1_k127_7854299_8 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 447.0
PYH1_k127_7854299_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 365.0
PYH1_k127_786809_0 FAD dependent oxidoreductase K06954 - - 2.937e-201 648.0
PYH1_k127_786809_1 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 502.0
PYH1_k127_786809_2 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 429.0
PYH1_k127_786809_3 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 347.0
PYH1_k127_786809_4 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000004214 226.0
PYH1_k127_786809_5 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000004395 86.0
PYH1_k127_786809_6 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000666 102.0
PYH1_k127_7871694_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 467.0
PYH1_k127_7871694_1 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 385.0
PYH1_k127_7871694_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 353.0
PYH1_k127_7871694_3 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000004576 262.0
PYH1_k127_7871694_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000001179 258.0
PYH1_k127_7871694_5 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000001538 89.0
PYH1_k127_7871694_6 Domain of unknown function (DUF1732) - - - 0.00000002 66.0
PYH1_k127_7896372_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1603.0
PYH1_k127_7896372_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1545.0
PYH1_k127_7896372_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 505.0
PYH1_k127_7896372_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 465.0
PYH1_k127_7896372_12 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 450.0
PYH1_k127_7896372_13 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 428.0
PYH1_k127_7896372_14 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 414.0
PYH1_k127_7896372_15 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 430.0
PYH1_k127_7896372_16 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 410.0
PYH1_k127_7896372_17 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 387.0
PYH1_k127_7896372_18 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 384.0
PYH1_k127_7896372_19 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 369.0
PYH1_k127_7896372_2 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 3.564e-292 909.0
PYH1_k127_7896372_20 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 302.0
PYH1_k127_7896372_21 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001889 296.0
PYH1_k127_7896372_22 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003222 280.0
PYH1_k127_7896372_23 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000002995 243.0
PYH1_k127_7896372_24 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000000000000000000000000000000000000000000001242 213.0
PYH1_k127_7896372_25 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000003716 180.0
PYH1_k127_7896372_26 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000001769 130.0
PYH1_k127_7896372_27 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000002625 117.0
PYH1_k127_7896372_3 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 5.28e-262 834.0
PYH1_k127_7896372_4 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 2.168e-237 752.0
PYH1_k127_7896372_5 Domain of unknown function (DUF4070) - - - 4.732e-219 688.0
PYH1_k127_7896372_6 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.321e-209 659.0
PYH1_k127_7896372_7 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 531.0
PYH1_k127_7896372_8 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 534.0
PYH1_k127_7896372_9 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 513.0
PYH1_k127_7908513_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.658e-200 634.0
PYH1_k127_7908513_1 Glyoxalase bleomycin resistance - - - 0.00000000000000000000000000000000000000000000000000001838 190.0
PYH1_k127_7908513_2 response regulator - - - 0.00000000000000000000000000000000000000001188 163.0
PYH1_k127_7908513_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000001187 145.0
PYH1_k127_7908513_4 Cupin domain - - - 0.000000000000000000000000000000000001566 145.0
PYH1_k127_7908513_5 PFAM ribosomal protein L31 K02909 - - 0.00000000000000000000000000002571 119.0
PYH1_k127_7910818_0 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000004026 212.0
PYH1_k127_7910818_1 FAD binding domain - - - 0.00001744 56.0
PYH1_k127_7916693_0 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 419.0
PYH1_k127_7916693_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000004884 92.0
PYH1_k127_7916693_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000003286 84.0
PYH1_k127_7946602_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1405.0
PYH1_k127_7946602_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 458.0
PYH1_k127_7946602_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 349.0
PYH1_k127_7946602_3 negative regulation of establishment of protein localization K02570 - - 0.000000000000002667 82.0
PYH1_k127_7946602_4 4Fe-4S dicluster domain K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.0000000001449 66.0
PYH1_k127_7949860_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 438.0
PYH1_k127_7949860_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 282.0
PYH1_k127_7949860_2 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000001214 92.0
PYH1_k127_7970034_0 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 387.0
PYH1_k127_7970034_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000009496 203.0
PYH1_k127_7970034_2 Ubiquinone biosynthesis - - - 0.0000000000000005323 79.0
PYH1_k127_7985773_0 4Fe-4S dicluster domain - - - 0.0 1242.0
PYH1_k127_7985773_1 Belongs to the IlvD Edd family - - - 8.887e-284 884.0
PYH1_k127_7985773_10 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 483.0
PYH1_k127_7985773_11 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 491.0
PYH1_k127_7985773_12 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 450.0
PYH1_k127_7985773_13 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 401.0
PYH1_k127_7985773_14 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 384.0
PYH1_k127_7985773_15 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 383.0
PYH1_k127_7985773_16 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 368.0
PYH1_k127_7985773_17 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 374.0
PYH1_k127_7985773_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 364.0
PYH1_k127_7985773_19 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 340.0
PYH1_k127_7985773_2 Protein of unknown function, DUF255 K06888 - - 6.286e-249 790.0
PYH1_k127_7985773_20 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 317.0
PYH1_k127_7985773_21 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 310.0
PYH1_k127_7985773_22 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 306.0
PYH1_k127_7985773_23 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 291.0
PYH1_k127_7985773_24 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000109 259.0
PYH1_k127_7985773_25 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 248.0
PYH1_k127_7985773_26 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000006211 238.0
PYH1_k127_7985773_27 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
PYH1_k127_7985773_28 PFAM Bacterial protein of - - - 0.0000000000000000000000000000000000000000000000000000000000001738 218.0
PYH1_k127_7985773_29 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000006799 212.0
PYH1_k127_7985773_3 PFAM AMP-dependent synthetase and ligase - - - 4.086e-230 722.0
PYH1_k127_7985773_30 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001378 188.0
PYH1_k127_7985773_31 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000001176 175.0
PYH1_k127_7985773_32 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000000002244 152.0
PYH1_k127_7985773_33 SMART Transport-associated and nodulation region K04065 - - 0.0000000001539 73.0
PYH1_k127_7985773_4 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 604.0
PYH1_k127_7985773_5 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 592.0
PYH1_k127_7985773_6 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 590.0
PYH1_k127_7985773_7 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 551.0
PYH1_k127_7985773_8 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 550.0
PYH1_k127_7985773_9 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 498.0
PYH1_k127_8003381_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 380.0
PYH1_k127_8003381_1 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000001441 185.0
PYH1_k127_8003381_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000001976 150.0
PYH1_k127_8003381_3 transcriptional - - - 0.000000000000000000000000000000000000002212 161.0
PYH1_k127_8003381_4 Bacterial SH3 domain - - - 0.00000000000000000000000000000000003473 138.0
PYH1_k127_8003381_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000006571 117.0
PYH1_k127_8029515_0 response regulator K02481 - - 2.511e-214 679.0
PYH1_k127_8029515_1 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 527.0
PYH1_k127_8029515_10 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001652 257.0
PYH1_k127_8029515_11 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000002254 237.0
PYH1_k127_8029515_12 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000001756 232.0
PYH1_k127_8029515_13 response regulator - - - 0.00000000000000000000000000000000000000000000000000003461 198.0
PYH1_k127_8029515_14 Pfam Response regulator receiver - - - 0.00000000000000000000000000000000000000000003178 167.0
PYH1_k127_8029515_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 379.0
PYH1_k127_8029515_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 357.0
PYH1_k127_8029515_4 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 342.0
PYH1_k127_8029515_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 331.0
PYH1_k127_8029515_6 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 325.0
PYH1_k127_8029515_7 4-carboxy-4-hydroxy-2-oxoadipate aldolase oxaloacetate decarboxylase K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 303.0
PYH1_k127_8029515_8 4,5-dihydroxyphthalate decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000419 279.0
PYH1_k127_8029515_9 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003594 275.0
PYH1_k127_8032557_0 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 514.0
PYH1_k127_8032557_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 419.0
PYH1_k127_8032557_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
PYH1_k127_8032557_3 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001603 275.0
PYH1_k127_8032557_4 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000004202 174.0
PYH1_k127_8032557_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000000002137 165.0
PYH1_k127_8032557_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000001717 63.0
PYH1_k127_8041407_0 Prolyl oligopeptidase family - - - 5.8e-245 776.0
PYH1_k127_8041407_1 Zn_pept - - - 1.005e-228 721.0
PYH1_k127_8041407_10 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000004796 194.0
PYH1_k127_8041407_11 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000002864 194.0
PYH1_k127_8041407_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000000001093 190.0
PYH1_k127_8041407_13 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000007277 173.0
PYH1_k127_8041407_14 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.00000000000000000000000000000004067 134.0
PYH1_k127_8041407_16 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000001499 96.0
PYH1_k127_8041407_2 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 379.0
PYH1_k127_8041407_3 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 325.0
PYH1_k127_8041407_4 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 296.0
PYH1_k127_8041407_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 298.0
PYH1_k127_8041407_6 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001469 263.0
PYH1_k127_8041407_7 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000049 246.0
PYH1_k127_8041407_8 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000001022 241.0
PYH1_k127_8041407_9 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000004738 218.0
PYH1_k127_8065615_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 3.373e-284 889.0
PYH1_k127_8065615_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 4.5e-215 679.0
PYH1_k127_8065615_2 GntR family - - - 0.000000000000000000000000001618 115.0
PYH1_k127_8065615_3 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000006599 58.0
PYH1_k127_8093996_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2353.0
PYH1_k127_8093996_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1287.0
PYH1_k127_8093996_10 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 503.0
PYH1_k127_8093996_11 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 528.0
PYH1_k127_8093996_12 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 478.0
PYH1_k127_8093996_13 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 439.0
PYH1_k127_8093996_14 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 433.0
PYH1_k127_8093996_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 439.0
PYH1_k127_8093996_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 331.0
PYH1_k127_8093996_17 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 317.0
PYH1_k127_8093996_18 NAD dependent epimerase/dehydratase family K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 305.0
PYH1_k127_8093996_19 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 299.0
PYH1_k127_8093996_2 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 5e-324 1007.0
PYH1_k127_8093996_20 Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
PYH1_k127_8093996_21 SMART cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000002088 229.0
PYH1_k127_8093996_22 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000363 218.0
PYH1_k127_8093996_23 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000001662 207.0
PYH1_k127_8093996_24 fimbrial biogenesis protein PilN K02663 - - 0.000000000000000000000000000000000000000000000000000000004603 209.0
PYH1_k127_8093996_25 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000006967 193.0
PYH1_k127_8093996_26 Inorganic ion transport and metabolism K06202 - - 0.00000000000000000000000000000526 131.0
PYH1_k127_8093996_27 Rubrerythrin - - - 0.00000000000000000000000000004071 133.0
PYH1_k127_8093996_28 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000001236 123.0
PYH1_k127_8093996_29 pilus assembly protein pilp K02665 - - 0.000000000000000000000002662 111.0
PYH1_k127_8093996_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.435e-287 894.0
PYH1_k127_8093996_30 Cytochrome c - - - 0.0000000000000959 74.0
PYH1_k127_8093996_31 ABC transporter substrate binding protein K01989 - - 0.0001024 46.0
PYH1_k127_8093996_4 Type 4 fimbrial biogenesis protein K02666 - - 9.287e-245 778.0
PYH1_k127_8093996_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.585e-239 747.0
PYH1_k127_8093996_6 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.497e-223 706.0
PYH1_k127_8093996_7 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 577.0
PYH1_k127_8093996_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 560.0
PYH1_k127_8093996_9 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 520.0
PYH1_k127_8097282_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 323.0
PYH1_k127_8097282_1 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 295.0
PYH1_k127_8097282_2 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000005201 245.0
PYH1_k127_8097282_3 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000001894 178.0
PYH1_k127_8097282_4 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000001848 139.0
PYH1_k127_8097282_5 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000002643 130.0
PYH1_k127_8097282_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000001331 55.0
PYH1_k127_8106309_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 5.656e-225 721.0
PYH1_k127_8106309_1 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 496.0
PYH1_k127_8106309_2 succinate-semialdehyde dehydrogenase (NAD+) activity K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 398.0
PYH1_k127_8106309_3 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 366.0
PYH1_k127_8106309_4 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000002757 272.0
PYH1_k127_8106309_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
PYH1_k127_8108681_0 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 387.0
PYH1_k127_8108681_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 368.0
PYH1_k127_8108681_2 Male sterility protein K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 358.0
PYH1_k127_8108681_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00001479 50.0
PYH1_k127_8114233_0 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 321.0
PYH1_k127_8114233_1 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000003683 181.0
PYH1_k127_8114233_2 membrane transporter protein K07090 - - 0.0000000001131 66.0
PYH1_k127_8131505_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 6.272e-199 629.0
PYH1_k127_8131505_1 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 308.0
PYH1_k127_8131505_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000001354 141.0
PYH1_k127_8141023_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 581.0
PYH1_k127_8141023_1 LexA DNA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002754 262.0
PYH1_k127_8141023_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006015 263.0
PYH1_k127_8141023_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004356 268.0
PYH1_k127_8141023_4 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
PYH1_k127_8141023_5 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000003561 197.0
PYH1_k127_8141023_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000003844 129.0
PYH1_k127_8157282_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 338.0
PYH1_k127_8157282_1 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0
PYH1_k127_8157282_2 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000002961 165.0
PYH1_k127_8157282_3 Fumarate reductase subunit C - - - 0.00000000000000000000000000001526 132.0
PYH1_k127_8157282_4 Fumarate reductase subunit D - - - 0.000000000000000000000007359 104.0
PYH1_k127_8163762_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 301.0
PYH1_k127_8163762_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 293.0
PYH1_k127_8163762_2 branched-chain amino acid transport K01996 - - 0.00000000000000000000000000000000000000000000000000000001848 199.0
PYH1_k127_8163762_3 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000006653 141.0
PYH1_k127_8163762_4 Cupin 2, conserved barrel domain protein K19547 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897 5.3.3.19 0.0000000000000000000000003186 111.0
PYH1_k127_8163762_5 OmpA-like transmembrane domain K03286 - - 0.0000000000000001257 88.0
PYH1_k127_8163762_6 V4R - - - 0.000000004826 59.0
PYH1_k127_8200878_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 543.0
PYH1_k127_8200878_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 447.0
PYH1_k127_8200878_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000004419 141.0
PYH1_k127_8200878_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000198 100.0
PYH1_k127_8200878_4 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000001723 62.0
PYH1_k127_8205074_0 PFAM AMP-dependent synthetase and ligase K12508 - 6.2.1.34 3.765e-208 664.0
PYH1_k127_8205074_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 533.0
PYH1_k127_8205074_10 catechol 1,2-dioxygenase - - - 0.00000000000000000000000000000000007734 149.0
PYH1_k127_8205074_11 (Lipo)protein - - - 0.000000000000005126 85.0
PYH1_k127_8205074_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 464.0
PYH1_k127_8205074_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 424.0
PYH1_k127_8205074_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 415.0
PYH1_k127_8205074_5 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
PYH1_k127_8205074_6 Preprotein translocase subunit TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000001908 233.0
PYH1_k127_8205074_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000006179 220.0
PYH1_k127_8205074_8 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000000000000000000000000008918 214.0
PYH1_k127_8205074_9 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000008285 196.0
PYH1_k127_8215748_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.231e-194 615.0
PYH1_k127_8215748_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000005359 203.0
PYH1_k127_8215748_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000001359 193.0
PYH1_k127_8215748_3 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000006144 147.0
PYH1_k127_8215748_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000002305 105.0
PYH1_k127_8220765_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.7e-322 997.0
PYH1_k127_8220765_1 Alkyl sulfatase C-terminal - - - 5.742e-300 936.0
PYH1_k127_8220765_10 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008121 250.0
PYH1_k127_8220765_11 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000001064 250.0
PYH1_k127_8220765_12 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000002485 237.0
PYH1_k127_8220765_13 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000002485 231.0
PYH1_k127_8220765_14 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000004201 226.0
PYH1_k127_8220765_15 hydratase decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000059 203.0
PYH1_k127_8220765_16 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000002458 208.0
PYH1_k127_8220765_17 Histidine kinase - - - 0.000000000000000000000000000001023 132.0
PYH1_k127_8220765_18 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000006715 117.0
PYH1_k127_8220765_19 Cytochrome P460 - - - 0.000000000000000000001102 110.0
PYH1_k127_8220765_2 Ferrous iron transport protein B K04759 - - 4.031e-221 705.0
PYH1_k127_8220765_20 cytochrome - - - 0.000000000000001025 91.0
PYH1_k127_8220765_3 OPT oligopeptide transporter protein - - - 1.662e-200 640.0
PYH1_k127_8220765_4 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 434.0
PYH1_k127_8220765_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 325.0
PYH1_k127_8220765_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 314.0
PYH1_k127_8220765_7 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001967 285.0
PYH1_k127_8220765_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 284.0
PYH1_k127_8220765_9 Response regulator of the LytR AlgR family K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004888 253.0
PYH1_k127_8224793_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 317.0
PYH1_k127_8224793_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
PYH1_k127_8224793_2 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000275 169.0
PYH1_k127_8224793_3 Preprotein translocase subunit TatD K03424 - - 0.000000000000000000006015 100.0
PYH1_k127_8247101_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1279.0
PYH1_k127_8247101_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 598.0
PYH1_k127_8247101_10 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000009403 170.0
PYH1_k127_8247101_11 Thioesterase - - - 0.000000000000000000000000000000000000000000002749 167.0
PYH1_k127_8247101_12 transcriptional regulator - - - 0.000000000000000000000005178 118.0
PYH1_k127_8247101_13 Hemerythrin HHE cation binding domain - - - 0.00000006609 57.0
PYH1_k127_8247101_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 504.0
PYH1_k127_8247101_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 385.0
PYH1_k127_8247101_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 383.0
PYH1_k127_8247101_5 4Fe-4S binding domain K18362 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 368.0
PYH1_k127_8247101_6 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 327.0
PYH1_k127_8247101_7 branched-chain amino acid transport K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 316.0
PYH1_k127_8247101_8 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002871 253.0
PYH1_k127_8247101_9 DMSO reductase anchor subunit (DmsC) K18363 - - 0.00000000000000000000000000000000000000000000000000000001502 216.0
PYH1_k127_8251525_0 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 508.0
PYH1_k127_8251525_1 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005521 465.0
PYH1_k127_8251525_10 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000003827 184.0
PYH1_k127_8251525_11 TPM domain - - - 0.0000000000000000000000000000000000000000000000004645 184.0
PYH1_k127_8251525_12 TspO MBR family protein K05770 - - 0.000000000000000000000000000000000000000000004839 175.0
PYH1_k127_8251525_13 PFAM Restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000001386 168.0
PYH1_k127_8251525_14 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000001492 155.0
PYH1_k127_8251525_15 HNH nucleases - - - 0.000000000000000000000000000000000000007477 147.0
PYH1_k127_8251525_16 - - - - 0.0000000000000000000000000000000007285 133.0
PYH1_k127_8251525_17 - - - - 0.000000000000000000000000000002059 123.0
PYH1_k127_8251525_18 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000001971 89.0
PYH1_k127_8251525_19 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0001621 46.0
PYH1_k127_8251525_2 HI0933-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 457.0
PYH1_k127_8251525_3 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 340.0
PYH1_k127_8251525_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 310.0
PYH1_k127_8251525_5 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000002026 246.0
PYH1_k127_8251525_6 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000005088 227.0
PYH1_k127_8251525_7 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
PYH1_k127_8251525_8 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000001686 223.0
PYH1_k127_8251525_9 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000000003315 193.0
PYH1_k127_8252608_0 ABC transporter transmembrane region K02021 - - 2.685e-272 865.0
PYH1_k127_8252608_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.115e-252 794.0
PYH1_k127_8252608_10 sulfite oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 432.0
PYH1_k127_8252608_11 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 420.0
PYH1_k127_8252608_12 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 390.0
PYH1_k127_8252608_13 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 394.0
PYH1_k127_8252608_14 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 376.0
PYH1_k127_8252608_15 Pfam:Kce - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 367.0
PYH1_k127_8252608_16 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 361.0
PYH1_k127_8252608_17 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 369.0
PYH1_k127_8252608_18 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 328.0
PYH1_k127_8252608_19 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007484 266.0
PYH1_k127_8252608_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 4.158e-213 680.0
PYH1_k127_8252608_20 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000004125 239.0
PYH1_k127_8252608_21 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008162 235.0
PYH1_k127_8252608_22 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000005174 221.0
PYH1_k127_8252608_23 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
PYH1_k127_8252608_24 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
PYH1_k127_8252608_25 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000002794 210.0
PYH1_k127_8252608_26 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000008411 213.0
PYH1_k127_8252608_27 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000005698 191.0
PYH1_k127_8252608_28 - - - - 0.0000000000000000000000000000000000000000000000005581 189.0
PYH1_k127_8252608_29 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000001021 177.0
PYH1_k127_8252608_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.923e-197 626.0
PYH1_k127_8252608_30 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000003589 171.0
PYH1_k127_8252608_31 Redoxin domain protein - - - 0.00000000000000000000000000000000000000001304 160.0
PYH1_k127_8252608_32 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000009594 148.0
PYH1_k127_8252608_33 Binding-protein-dependent transport system inner membrane component K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.000000001941 58.0
PYH1_k127_8252608_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 602.0
PYH1_k127_8252608_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 563.0
PYH1_k127_8252608_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 551.0
PYH1_k127_8252608_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 529.0
PYH1_k127_8252608_8 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 514.0
PYH1_k127_8252608_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 462.0
PYH1_k127_8254018_0 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000076 224.0
PYH1_k127_8254018_1 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000003819 198.0
PYH1_k127_8266539_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1672.0
PYH1_k127_8266539_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1055.0
PYH1_k127_8266539_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000002785 185.0
PYH1_k127_8266539_11 membrane - - - 0.0000000000000000000000000000000000000000000000000901 183.0
PYH1_k127_8266539_12 - - - - 0.000000000000000000000000000000000000000008217 171.0
PYH1_k127_8266539_13 - - - - 0.000000000000000000000000000000000000001588 153.0
PYH1_k127_8266539_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000002974 136.0
PYH1_k127_8266539_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 471.0
PYH1_k127_8266539_3 (ABC) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 343.0
PYH1_k127_8266539_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 292.0
PYH1_k127_8266539_5 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004693 244.0
PYH1_k127_8266539_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000111 238.0
PYH1_k127_8266539_7 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
PYH1_k127_8266539_8 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000006195 218.0
PYH1_k127_8266539_9 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000003721 225.0
PYH1_k127_8328198_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 2.538e-196 625.0
PYH1_k127_8328198_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000001848 127.0
PYH1_k127_8328198_2 CoA-binding domain - - - 0.0000000000000000000000000000001785 125.0
PYH1_k127_83489_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 3.382e-196 637.0
PYH1_k127_83489_1 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 338.0
PYH1_k127_83489_2 heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000007177 191.0
PYH1_k127_83489_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000003876 152.0
PYH1_k127_8348974_0 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 383.0
PYH1_k127_8348974_1 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 369.0
PYH1_k127_8348974_2 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000002449 114.0
PYH1_k127_8348974_3 RDD family - - - 0.000000000000000000000007608 112.0
PYH1_k127_8348974_4 Protein of unknown function (DUF3619) - - - 0.000000000005319 68.0
PYH1_k127_852242_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 370.0
PYH1_k127_852242_1 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 308.0
PYH1_k127_852242_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001929 287.0
PYH1_k127_852242_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003586 259.0
PYH1_k127_852242_4 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000001532 157.0
PYH1_k127_852242_5 branched-chain amino acid K01995 - - 0.0000000000000000000000004414 119.0
PYH1_k127_938248_0 transcriptional Regulator, LysR family - - - 0.0000000000000000000000000000000000000000000001616 175.0
PYH1_k127_938248_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000001204 130.0
PYH1_k127_938248_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.000000000000001284 81.0
PYH1_k127_940560_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 1.075e-241 759.0
PYH1_k127_940560_1 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 7.992e-223 709.0
PYH1_k127_940560_10 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000001885 198.0
PYH1_k127_940560_11 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000002958 191.0
PYH1_k127_940560_12 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000006379 173.0
PYH1_k127_940560_13 general secretion pathway protein - - - 0.000000000000000000000000000000001723 148.0
PYH1_k127_940560_14 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000003514 137.0
PYH1_k127_940560_15 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000004923 121.0
PYH1_k127_940560_16 - - - - 0.0000000000000000000000005374 114.0
PYH1_k127_940560_17 - - - - 0.000000000000003999 82.0
PYH1_k127_940560_18 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000001209 77.0
PYH1_k127_940560_2 type II secretion system protein K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 492.0
PYH1_k127_940560_3 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 451.0
PYH1_k127_940560_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 414.0
PYH1_k127_940560_5 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 367.0
PYH1_k127_940560_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001532 258.0
PYH1_k127_940560_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004552 236.0
PYH1_k127_940560_9 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000002739 198.0
PYH1_k127_952758_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1234.0
PYH1_k127_952758_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.563e-215 673.0
PYH1_k127_952758_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000005214 126.0
PYH1_k127_952758_11 - - - - 0.0000000000000008718 79.0
PYH1_k127_952758_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 526.0
PYH1_k127_952758_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 473.0
PYH1_k127_952758_4 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 398.0
PYH1_k127_952758_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 401.0
PYH1_k127_952758_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 349.0
PYH1_k127_952758_7 phytoene K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
PYH1_k127_952758_8 squalene-associated FAD-dependent desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 327.0
PYH1_k127_952758_9 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000001264 149.0
PYH1_k127_980115_0 PERMEase K06901 - - 7.485e-222 709.0
PYH1_k127_980115_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.505e-205 653.0
PYH1_k127_980115_10 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 336.0
PYH1_k127_980115_11 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 328.0
PYH1_k127_980115_12 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 322.0
PYH1_k127_980115_13 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 327.0
PYH1_k127_980115_14 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001562 290.0
PYH1_k127_980115_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 7.434e-205 651.0
PYH1_k127_980115_3 Extracellular ligand-binding receptor K01999 - - 3.387e-195 615.0
PYH1_k127_980115_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 568.0
PYH1_k127_980115_5 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 550.0
PYH1_k127_980115_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 495.0
PYH1_k127_980115_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 444.0
PYH1_k127_980115_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 415.0
PYH1_k127_980115_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 387.0
PYH1_k127_997494_0 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 514.0
PYH1_k127_997494_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 383.0
PYH1_k127_997494_3 Cytochrome c - - - 0.00000000279 61.0
PYH1_k127_997494_4 FixH family K09926 - - 0.0001746 44.0