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Overview

ID MAG03208
Name PYH2_bin.67
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus G020354665
Species
Assembly information
Completeness (%) 86.78
Contamination (%) 1.44
GC content (%) 67.0
N50 (bp) 7,657
Genome size (bp) 3,742,354

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3909

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1018042_0 Adenylate and Guanylate cyclase catalytic domain - - - 6.451e-224 730.0
PYH2_k127_1027804_0 glutamine synthetase K01915 - 6.3.1.2 3.656e-280 863.0
PYH2_k127_1027804_1 Aldehyde dehydrogenase family K00130,K09472,K12254 - 1.2.1.54,1.2.1.8,1.2.1.99 4.965e-261 813.0
PYH2_k127_1027804_10 transport system permease K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 511.0
PYH2_k127_1027804_11 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 514.0
PYH2_k127_1027804_12 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 488.0
PYH2_k127_1027804_13 transport system permease K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 436.0
PYH2_k127_1027804_14 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 364.0
PYH2_k127_1027804_15 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000007774 261.0
PYH2_k127_1027804_16 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004239 250.0
PYH2_k127_1027804_17 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000003316 221.0
PYH2_k127_1027804_18 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000002377 202.0
PYH2_k127_1027804_19 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000002104 158.0
PYH2_k127_1027804_2 Isocitrate lyase K01637 - 4.1.3.1 1.447e-259 804.0
PYH2_k127_1027804_20 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000004849 160.0
PYH2_k127_1027804_21 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000001252 160.0
PYH2_k127_1027804_22 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000001067 128.0
PYH2_k127_1027804_23 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000001084 108.0
PYH2_k127_1027804_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 1.831e-252 782.0
PYH2_k127_1027804_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 3.386e-252 795.0
PYH2_k127_1027804_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836,K07250 - 2.6.1.19,2.6.1.22,2.6.1.76 3.342e-204 667.0
PYH2_k127_1027804_6 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 2.504e-201 632.0
PYH2_k127_1027804_7 FAD dependent oxidoreductase K09471 - - 8.176e-200 631.0
PYH2_k127_1027804_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 610.0
PYH2_k127_1027804_9 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 621.0
PYH2_k127_1029660_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 565.0
PYH2_k127_1029660_1 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
PYH2_k127_1029660_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002754 259.0
PYH2_k127_1029660_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000001486 157.0
PYH2_k127_1029660_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000001491 120.0
PYH2_k127_1029660_5 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000002475 65.0
PYH2_k127_1035898_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 3.792e-211 669.0
PYH2_k127_1035898_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 565.0
PYH2_k127_1035898_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000002356 53.0
PYH2_k127_1041912_0 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 585.0
PYH2_k127_1041912_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 353.0
PYH2_k127_1041912_2 Transcriptional regulatory protein, C terminal K07663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 336.0
PYH2_k127_1041912_3 Acyl-homoserine-lactone synthase K00831 - 2.6.1.52 0.00000000000000000000000000001072 124.0
PYH2_k127_1041912_4 - - - - 0.000000000000000000000000001611 113.0
PYH2_k127_1041912_5 PFAM MmgE PrpD family protein - - - 0.0000000000000000000000002177 108.0
PYH2_k127_1051563_0 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000002171 209.0
PYH2_k127_1051563_1 - - - - 0.0000000000000000000000000000000003577 139.0
PYH2_k127_1051563_2 membrane transporter protein K07090 - - 0.000000000000000000000000000001035 126.0
PYH2_k127_1057157_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 321.0
PYH2_k127_1057157_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000004885 157.0
PYH2_k127_1064721_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 496.0
PYH2_k127_1064721_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 342.0
PYH2_k127_1064721_2 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000001284 152.0
PYH2_k127_1064721_3 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000000000003897 143.0
PYH2_k127_1064721_4 His Kinase A (phosphoacceptor) domain K07654 - 2.7.13.3 0.00007035 49.0
PYH2_k127_1103561_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 481.0
PYH2_k127_1103561_1 - - - - 0.000000000000000000000000000000000000009271 149.0
PYH2_k127_1103561_2 Protein of unknown function (DUF2905) - - - 0.000000000000000000001156 96.0
PYH2_k127_1103561_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00003576 52.0
PYH2_k127_1104224_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 538.0
PYH2_k127_1109090_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 584.0
PYH2_k127_1109090_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 585.0
PYH2_k127_1109090_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 550.0
PYH2_k127_1109090_3 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 464.0
PYH2_k127_1109090_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 445.0
PYH2_k127_1109090_5 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 399.0
PYH2_k127_1109090_6 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 392.0
PYH2_k127_1109090_7 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 308.0
PYH2_k127_1109090_8 Nad-dependent epimerase dehydratase - - - 0.0000000000000001535 93.0
PYH2_k127_1111020_0 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 561.0
PYH2_k127_1111020_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000001569 240.0
PYH2_k127_1111020_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000008534 150.0
PYH2_k127_1111020_3 - - - - 0.00000000000000000000000001469 126.0
PYH2_k127_1115073_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1186.0
PYH2_k127_1115073_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 415.0
PYH2_k127_1115073_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 381.0
PYH2_k127_1115073_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000009624 259.0
PYH2_k127_1115073_4 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001283 229.0
PYH2_k127_1115073_5 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000000000000000000000000000000000000000000000000000000002486 223.0
PYH2_k127_1115073_6 VWA domain containing CoxE-like protein - - - 0.00000000000000000000001601 106.0
PYH2_k127_113077_0 cytochrome C K02198 - - 0.0 1038.0
PYH2_k127_113077_1 Required for chromosome condensation and partitioning K03529 - - 7.595e-204 648.0
PYH2_k127_113077_2 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 569.0
PYH2_k127_113077_3 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 334.0
PYH2_k127_113077_4 Periplasmic protein thiol K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001594 277.0
PYH2_k127_113077_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000009291 254.0
PYH2_k127_113077_6 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000003427 171.0
PYH2_k127_113077_7 TonB C terminal - - - 0.000000003447 65.0
PYH2_k127_1132160_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 542.0
PYH2_k127_1132160_1 peptidase S1 and S6, chymotrypsin Hap K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 469.0
PYH2_k127_1132160_10 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000000000012 169.0
PYH2_k127_1132160_11 membrane - - - 0.0000000000000000000000000000000002342 141.0
PYH2_k127_1132160_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000005141 114.0
PYH2_k127_1132160_13 PFAM metallophosphoesterase K06953 - - 0.00001608 50.0
PYH2_k127_1132160_2 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 460.0
PYH2_k127_1132160_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 421.0
PYH2_k127_1132160_4 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 312.0
PYH2_k127_1132160_5 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 292.0
PYH2_k127_1132160_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000001163 234.0
PYH2_k127_1132160_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000000000000000000000000000000000004918 232.0
PYH2_k127_1132160_8 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000005719 235.0
PYH2_k127_1132160_9 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000000000000001434 210.0
PYH2_k127_1142849_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 522.0
PYH2_k127_1142849_1 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 386.0
PYH2_k127_1142849_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000007575 228.0
PYH2_k127_1142849_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000007244 201.0
PYH2_k127_1142849_4 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000005651 165.0
PYH2_k127_1142849_5 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000002182 102.0
PYH2_k127_1155293_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 531.0
PYH2_k127_1155293_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 353.0
PYH2_k127_1155293_2 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 344.0
PYH2_k127_1155293_3 Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 314.0
PYH2_k127_1155293_4 Crp Fnr family - - - 0.00000000000000000000000000000000000000001718 153.0
PYH2_k127_1155293_5 SMART Transport-associated and nodulation region K04065 - - 0.0000000000000000000000000000001013 136.0
PYH2_k127_1155293_6 - - - - 0.0000000000000000000000000006532 114.0
PYH2_k127_1155293_8 SMART Transport-associated and nodulation region K04065 - - 0.00000000000000009952 87.0
PYH2_k127_1155293_9 - - - - 0.0000000000000002691 80.0
PYH2_k127_1158041_0 Alkyl sulfatase C-terminal - - - 5e-324 1010.0
PYH2_k127_1158041_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.002e-258 806.0
PYH2_k127_1158041_10 PFAM regulatory protein LuxR - - - 0.00000000000009536 82.0
PYH2_k127_1158041_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 4.744e-246 764.0
PYH2_k127_1158041_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 3.987e-220 697.0
PYH2_k127_1158041_4 belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 586.0
PYH2_k127_1158041_5 Amino acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 288.0
PYH2_k127_1158041_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000006974 249.0
PYH2_k127_1158041_7 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000894 205.0
PYH2_k127_1158041_8 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000005829 190.0
PYH2_k127_1158041_9 ethyl tert-butyl ether degradation - - - 0.00000000000000000000000000000001218 135.0
PYH2_k127_1164945_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 448.0
PYH2_k127_1164945_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 360.0
PYH2_k127_1164945_10 Belongs to the UPF0434 family K09791 - - 0.00000000000000000002626 92.0
PYH2_k127_1164945_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 339.0
PYH2_k127_1164945_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 348.0
PYH2_k127_1164945_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 331.0
PYH2_k127_1164945_5 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 293.0
PYH2_k127_1164945_6 . ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. PFam MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000001696 219.0
PYH2_k127_1164945_7 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000003385 199.0
PYH2_k127_1164945_8 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000001068 195.0
PYH2_k127_1164945_9 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000005151 185.0
PYH2_k127_1172752_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.995e-320 998.0
PYH2_k127_1172752_1 Histidine kinase K07638 - 2.7.13.3 1.294e-219 689.0
PYH2_k127_1172752_2 Two component transcriptional regulator, winged helix family K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 454.0
PYH2_k127_1172752_3 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 407.0
PYH2_k127_1172752_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 405.0
PYH2_k127_1172752_5 nuclease K01174 - 3.1.31.1 0.00005571 47.0
PYH2_k127_1172752_6 transposase activity K07483 - - 0.0001254 46.0
PYH2_k127_1175296_0 PFAM Dehydrogenase, E1 component K00166 - 1.2.4.4 2.512e-226 706.0
PYH2_k127_1175296_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 2.28e-201 631.0
PYH2_k127_1175296_10 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes K09699 - 2.3.1.168 0.00000000000000000000000000000001427 130.0
PYH2_k127_1175296_11 - - - - 0.0000000000000006564 87.0
PYH2_k127_1175296_2 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 620.0
PYH2_k127_1175296_3 Periplasmic sensor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 562.0
PYH2_k127_1175296_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 377.0
PYH2_k127_1175296_5 transport system, periplasmic component K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 353.0
PYH2_k127_1175296_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 344.0
PYH2_k127_1175296_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000001477 209.0
PYH2_k127_1175296_8 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000009221 162.0
PYH2_k127_1175296_9 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000000000000000000003569 144.0
PYH2_k127_120143_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.361e-270 839.0
PYH2_k127_120143_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 563.0
PYH2_k127_120143_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 325.0
PYH2_k127_120143_3 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 303.0
PYH2_k127_120143_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000006321 159.0
PYH2_k127_120143_5 - - - - 0.00000000000000000000004254 110.0
PYH2_k127_1210005_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 612.0
PYH2_k127_1210005_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 517.0
PYH2_k127_1210005_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 377.0
PYH2_k127_1216520_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 2.586e-276 861.0
PYH2_k127_1216520_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 610.0
PYH2_k127_1216520_10 TIGRFAM phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000001994 105.0
PYH2_k127_1216520_13 Alpha/beta hydrolase family - - - 0.0000000001287 74.0
PYH2_k127_1216520_14 Protein of unknown function (DUF4197) - - - 0.0000000003321 64.0
PYH2_k127_1216520_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 443.0
PYH2_k127_1216520_3 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 349.0
PYH2_k127_1216520_4 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 342.0
PYH2_k127_1216520_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000001591 214.0
PYH2_k127_1216520_6 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000000005273 191.0
PYH2_k127_1216520_7 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000004684 163.0
PYH2_k127_1216520_8 - - - - 0.0000000000000000000000000000000000003276 148.0
PYH2_k127_1216520_9 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000005078 143.0
PYH2_k127_1254762_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1686.0
PYH2_k127_1254762_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 426.0
PYH2_k127_1256890_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1176.0
PYH2_k127_1269850_0 Pfam Enoyl-CoA hydratase isomerase K15513 - 4.1.2.44 1.431e-306 942.0
PYH2_k127_1269850_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 9.928e-291 904.0
PYH2_k127_1269850_2 Benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 5.117e-220 688.0
PYH2_k127_1269850_3 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 561.0
PYH2_k127_1269850_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122 - 1.17.1.9 0.00000000000000000000000000000000000002161 147.0
PYH2_k127_1306092_0 TIGRFAM taurine ABC transporter, periplasmic binding protein K15551 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 499.0
PYH2_k127_1306092_1 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 455.0
PYH2_k127_1306092_2 ABC transporter K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 454.0
PYH2_k127_1306092_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 339.0
PYH2_k127_1306092_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 268.0
PYH2_k127_1306092_5 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000001414 229.0
PYH2_k127_1306092_6 AAA domain, putative AbiEii toxin, Type IV TA system K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000001789 178.0
PYH2_k127_1306092_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000001057 168.0
PYH2_k127_1306092_8 - - - - 0.0000000000000000000000000000000001647 139.0
PYH2_k127_1306092_9 - - - - 0.0000000000000000000002445 103.0
PYH2_k127_1314480_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 440.0
PYH2_k127_1314480_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 352.0
PYH2_k127_1314480_2 Bacterial transcriptional repressor C-terminal K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001364 269.0
PYH2_k127_1331889_0 Major Facilitator - - - 5.82e-229 715.0
PYH2_k127_1331889_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 609.0
PYH2_k127_1331889_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 387.0
PYH2_k127_1331889_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 366.0
PYH2_k127_1331889_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 347.0
PYH2_k127_1331889_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 325.0
PYH2_k127_1331889_6 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000005826 253.0
PYH2_k127_1331889_7 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000001184 226.0
PYH2_k127_1331889_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000001049 142.0
PYH2_k127_1336329_0 NADPH-dependent glutamate synthase beta - - - 1.737e-309 954.0
PYH2_k127_1336329_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 418.0
PYH2_k127_1342443_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.853e-259 816.0
PYH2_k127_1342443_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 430.0
PYH2_k127_1342443_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000006934 250.0
PYH2_k127_1342443_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
PYH2_k127_1342443_4 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000003468 192.0
PYH2_k127_1342443_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000281 98.0
PYH2_k127_1342443_6 - - - - 0.00000000000000003527 85.0
PYH2_k127_1352917_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 7.353e-285 885.0
PYH2_k127_1352917_1 Belongs to the UbiD family K03182 - 4.1.1.98 5.488e-270 837.0
PYH2_k127_1352917_10 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001689 222.0
PYH2_k127_1352917_11 monooxygenase activity - - - 0.00000000000000000000000001029 119.0
PYH2_k127_1352917_2 lytic transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 357.0
PYH2_k127_1352917_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 346.0
PYH2_k127_1352917_4 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 326.0
PYH2_k127_1352917_5 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004515 273.0
PYH2_k127_1352917_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000003917 256.0
PYH2_k127_1352917_7 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000001325 241.0
PYH2_k127_1352917_8 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001233 243.0
PYH2_k127_1352917_9 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
PYH2_k127_1380075_0 Transposase DDE domain group 1 - - - 7.679e-198 625.0
PYH2_k127_1380075_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000002422 207.0
PYH2_k127_1380075_2 PFAM Integrase catalytic region K07494 - - 0.0000000000000002073 80.0
PYH2_k127_1401519_0 Belongs to the IlvD Edd family K01687,K13875,K22186 - 4.2.1.25,4.2.1.82,4.2.1.9 0.0 1074.0
PYH2_k127_1401519_1 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 1.353e-282 888.0
PYH2_k127_1401519_2 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 6.661e-230 722.0
PYH2_k127_1401519_3 FAD dependent oxidoreductase - - - 1.892e-198 631.0
PYH2_k127_1401519_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 392.0
PYH2_k127_1401519_5 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
PYH2_k127_1401519_6 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000008589 250.0
PYH2_k127_1401519_7 - - - - 0.0000000000000000000000000000000000000000001552 178.0
PYH2_k127_1401519_8 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.000000002535 59.0
PYH2_k127_1433478_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1088.0
PYH2_k127_1433478_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.0 1037.0
PYH2_k127_1433478_10 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 521.0
PYH2_k127_1433478_11 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 509.0
PYH2_k127_1433478_12 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 521.0
PYH2_k127_1433478_13 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 499.0
PYH2_k127_1433478_14 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 484.0
PYH2_k127_1433478_15 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 481.0
PYH2_k127_1433478_16 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 482.0
PYH2_k127_1433478_17 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 473.0
PYH2_k127_1433478_18 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 460.0
PYH2_k127_1433478_19 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 464.0
PYH2_k127_1433478_2 Belongs to the GPI family K01810 - 5.3.1.9 8.704e-267 829.0
PYH2_k127_1433478_20 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 429.0
PYH2_k127_1433478_21 PFAM helix-turn-helix protein RpiR K19337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 429.0
PYH2_k127_1433478_22 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 435.0
PYH2_k127_1433478_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 419.0
PYH2_k127_1433478_24 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 418.0
PYH2_k127_1433478_25 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 408.0
PYH2_k127_1433478_26 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 410.0
PYH2_k127_1433478_27 acid transport system permease K09970 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 395.0
PYH2_k127_1433478_28 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 362.0
PYH2_k127_1433478_29 Bacterial transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 361.0
PYH2_k127_1433478_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.115e-264 820.0
PYH2_k127_1433478_30 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 348.0
PYH2_k127_1433478_31 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008797 339.0
PYH2_k127_1433478_32 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 335.0
PYH2_k127_1433478_33 toluene tolerance K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 284.0
PYH2_k127_1433478_34 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007025 265.0
PYH2_k127_1433478_35 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000006321 220.0
PYH2_k127_1433478_36 Haloacid dehalogenase-like hydrolase K07025,K20866 - 3.1.3.10 0.000000000000000000000000000000000000000000000000000006532 197.0
PYH2_k127_1433478_37 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000000000000000000000000000000000000003104 163.0
PYH2_k127_1433478_38 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000000003239 140.0
PYH2_k127_1433478_39 acyl-coA-binding protein - - - 0.00000000000000000000000000000001099 147.0
PYH2_k127_1433478_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 1.088e-223 700.0
PYH2_k127_1433478_40 - - - - 0.0000000000001899 79.0
PYH2_k127_1433478_41 STAS domain K07122 - - 0.00000000005044 71.0
PYH2_k127_1433478_42 Methyltransferase K08316 - 2.1.1.171 0.0000002026 59.0
PYH2_k127_1433478_5 Protein of unknown function (DUF1298) - - - 8.362e-220 699.0
PYH2_k127_1433478_6 Peptidase dimerisation domain - - - 9.016e-219 686.0
PYH2_k127_1433478_7 Neisseria PilC beta-propeller domain K02674 - - 2.196e-213 694.0
PYH2_k127_1433478_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.21e-210 660.0
PYH2_k127_1433478_9 Extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 599.0
PYH2_k127_144864_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1760.0
PYH2_k127_144864_1 PFAM acyl-CoA dehydrogenase domain protein K20035 - - 1.256e-308 954.0
PYH2_k127_144864_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 3.995e-279 864.0
PYH2_k127_144864_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 599.0
PYH2_k127_144864_4 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 499.0
PYH2_k127_144864_5 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 504.0
PYH2_k127_144864_6 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 432.0
PYH2_k127_144864_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 434.0
PYH2_k127_144864_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000009645 203.0
PYH2_k127_1463267_0 ATP-binding region, ATPase domain protein K02487,K06596 - - 1.306e-295 919.0
PYH2_k127_1463267_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 2.892e-232 739.0
PYH2_k127_1463267_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 318.0
PYH2_k127_1495991_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.231e-228 717.0
PYH2_k127_1495991_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 572.0
PYH2_k127_1495991_2 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 369.0
PYH2_k127_1495991_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000013 142.0
PYH2_k127_1515700_0 Ftsk_gamma K03466 - - 0.0 1145.0
PYH2_k127_1515700_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006712 278.0
PYH2_k127_1515700_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002896 276.0
PYH2_k127_1542742_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1097.0
PYH2_k127_1542742_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 555.0
PYH2_k127_1542742_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 547.0
PYH2_k127_1542742_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 287.0
PYH2_k127_1542742_4 Cell wall-associated K13695,K19303 - - 0.000000000000000000000000000000000000000000000000000000004582 204.0
PYH2_k127_1542742_5 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000000000000001869 139.0
PYH2_k127_1554602_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1023.0
PYH2_k127_1554602_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 416.0
PYH2_k127_1554602_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 400.0
PYH2_k127_1554602_3 hydroperoxide reductase activity K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000007585 226.0
PYH2_k127_1584178_0 Protein of unknown function (DUF1116) - - - 1.89e-257 810.0
PYH2_k127_1584178_1 CoA binding domain K02381 - - 1.767e-221 703.0
PYH2_k127_1584178_2 Amino acid kinase family K00926 - 2.7.2.2 2.503e-217 682.0
PYH2_k127_1584178_3 Hydrolase K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 376.0
PYH2_k127_1584178_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009031 259.0
PYH2_k127_1584178_5 Urea transporter - - - 0.0000000000000000000000000000000006972 145.0
PYH2_k127_1584178_6 Protein of unknown function (DUF2877) - - - 0.0000000002122 72.0
PYH2_k127_1591084_0 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 412.0
PYH2_k127_1591084_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 344.0
PYH2_k127_1591084_10 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000002382 209.0
PYH2_k127_1591084_11 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000007237 197.0
PYH2_k127_1591084_12 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000009404 180.0
PYH2_k127_1591084_13 - - - - 0.000000000000000000000000000000000000003699 148.0
PYH2_k127_1591084_14 - - - - 0.0000000000000000000000000000000005571 140.0
PYH2_k127_1591084_15 - - - - 0.0000000000000000000000000001252 118.0
PYH2_k127_1591084_16 manually curated - - - 0.0000000000000000000000000001394 126.0
PYH2_k127_1591084_17 Flagellar basal body rod protein - - - 0.000000000000000000005968 95.0
PYH2_k127_1591084_19 - - - - 0.000000000000000004816 87.0
PYH2_k127_1591084_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 320.0
PYH2_k127_1591084_20 Protein of unknown function (DUF2845) - - - 0.000000000000007493 85.0
PYH2_k127_1591084_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003701 278.0
PYH2_k127_1591084_4 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003315 261.0
PYH2_k127_1591084_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000302 258.0
PYH2_k127_1591084_6 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000818 249.0
PYH2_k127_1591084_7 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000001937 256.0
PYH2_k127_1591084_8 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001084 223.0
PYH2_k127_1591084_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000003439 224.0
PYH2_k127_1617689_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 7.35e-277 858.0
PYH2_k127_1617689_1 Transposase DDE domain - - - 1.844e-222 704.0
PYH2_k127_1617689_2 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 355.0
PYH2_k127_1617689_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 290.0
PYH2_k127_1617689_4 signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000012 295.0
PYH2_k127_1617689_5 Pfam Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005378 279.0
PYH2_k127_1617689_6 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000002078 214.0
PYH2_k127_1617689_7 RNA-binding protein - - - 0.0000000000000000000000000000000000000000000000003747 177.0
PYH2_k127_1617689_8 - - - - 0.000000000000000000000000000000000000000000000001542 177.0
PYH2_k127_1618062_0 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 418.0
PYH2_k127_1618062_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000217 142.0
PYH2_k127_1618062_2 Transporter K11688,K21395 - - 0.00000000000000005941 86.0
PYH2_k127_1626291_0 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1381.0
PYH2_k127_1626291_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 295.0
PYH2_k127_1626291_2 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001107 264.0
PYH2_k127_1626291_3 Carboxylesterase family K01066 - - 0.0000000000000000000000000000000000000000000000000000000000005165 218.0
PYH2_k127_1626291_4 Sporulation domain protein - - - 0.00000000000000000000000000000000000005596 151.0
PYH2_k127_1652483_0 MMPL family K03296,K18138,K18902 - - 1.569e-302 948.0
PYH2_k127_1652483_1 RND efflux system, outer membrane lipoprotein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 340.0
PYH2_k127_1652483_2 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
PYH2_k127_1656878_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1012.0
PYH2_k127_1656878_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 3.464e-254 794.0
PYH2_k127_1656878_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 336.0
PYH2_k127_1656878_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000000000004413 185.0
PYH2_k127_1656878_4 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000000000000000000001009 109.0
PYH2_k127_1673094_0 Surface antigen K07001 - - 5.627e-307 955.0
PYH2_k127_1673094_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 529.0
PYH2_k127_1673094_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000004807 113.0
PYH2_k127_169100_0 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 476.0
PYH2_k127_169100_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000006109 233.0
PYH2_k127_169100_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000001245 85.0
PYH2_k127_1698420_0 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 479.0
PYH2_k127_1698420_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 411.0
PYH2_k127_1698420_2 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 357.0
PYH2_k127_1708395_0 Histidine kinase - - - 9.904e-230 735.0
PYH2_k127_1708395_1 response regulator K22010 - - 0.000000000000000000000000000000000000000000000000000000002178 203.0
PYH2_k127_1712909_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1255.0
PYH2_k127_1712909_1 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 404.0
PYH2_k127_1728030_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 576.0
PYH2_k127_1728030_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 370.0
PYH2_k127_1728030_2 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000002895 192.0
PYH2_k127_1737840_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.494e-247 775.0
PYH2_k127_1737840_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 539.0
PYH2_k127_1737840_2 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
PYH2_k127_1737840_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 373.0
PYH2_k127_1745662_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1226.0
PYH2_k127_1745662_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1139.0
PYH2_k127_1745662_10 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000000000002429 216.0
PYH2_k127_1745662_11 Low molecular weight phosphotyrosine protein phosphatase K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000001343 208.0
PYH2_k127_1745662_12 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000000001278 190.0
PYH2_k127_1745662_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000000007706 157.0
PYH2_k127_1745662_14 - - - - 0.0000000000000000005084 91.0
PYH2_k127_1745662_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 4.205e-280 872.0
PYH2_k127_1745662_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.005e-237 737.0
PYH2_k127_1745662_4 PFAM PHB de-polymerase domain protein K05973 - 3.1.1.75 1.352e-227 710.0
PYH2_k127_1745662_5 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 546.0
PYH2_k127_1745662_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 514.0
PYH2_k127_1745662_7 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 323.0
PYH2_k127_1745662_8 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001613 240.0
PYH2_k127_1745662_9 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000002543 228.0
PYH2_k127_1763427_0 Phosphoesterase family K01114 - 3.1.4.3 6.624e-210 665.0
PYH2_k127_1763427_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 5.768e-204 641.0
PYH2_k127_1763427_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 308.0
PYH2_k127_1782519_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 3.641e-261 816.0
PYH2_k127_1782519_1 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 340.0
PYH2_k127_1795224_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 5.625e-286 893.0
PYH2_k127_1795224_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000338 132.0
PYH2_k127_1799751_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 2083.0
PYH2_k127_1799751_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 468.0
PYH2_k127_1799751_2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 451.0
PYH2_k127_1799751_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000007993 195.0
PYH2_k127_1799751_4 Phasin protein - - - 0.0003362 49.0
PYH2_k127_180588_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1535.0
PYH2_k127_180588_1 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 425.0
PYH2_k127_180588_2 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009228 259.0
PYH2_k127_180588_3 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000001431 230.0
PYH2_k127_180588_4 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000007408 156.0
PYH2_k127_1852169_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 463.0
PYH2_k127_1852169_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000005383 196.0
PYH2_k127_1852169_2 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000003893 163.0
PYH2_k127_1865713_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.508e-232 731.0
PYH2_k127_1865713_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 6.625e-220 701.0
PYH2_k127_1865713_2 PERMEase K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 556.0
PYH2_k127_1865713_3 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 472.0
PYH2_k127_1865713_4 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 405.0
PYH2_k127_1865713_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 351.0
PYH2_k127_1865713_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 334.0
PYH2_k127_1865713_7 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000008984 88.0
PYH2_k127_1871628_0 Mota tolq exbb proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
PYH2_k127_1871628_1 system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000000001273 169.0
PYH2_k127_1871628_2 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000006196 166.0
PYH2_k127_1871628_3 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000001209 158.0
PYH2_k127_1871628_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000004544 95.0
PYH2_k127_1887063_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 392.0
PYH2_k127_1887063_1 demethylmenaquinone methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 381.0
PYH2_k127_1887063_2 Formate dehydrogenase, alpha subunit K00123,K22015 - 1.17.1.9,1.17.99.7 0.00000000000000000000000000000000000000000000000000000000000008545 215.0
PYH2_k127_1887063_3 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000008473 205.0
PYH2_k127_1887063_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000003486 142.0
PYH2_k127_1900347_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1049.0
PYH2_k127_1900347_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 474.0
PYH2_k127_1900347_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 319.0
PYH2_k127_1900347_3 Fasciclin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 320.0
PYH2_k127_1900347_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 287.0
PYH2_k127_1900347_5 Beta-Ig-H3 fasciclin - - - 0.000000000000000000000000000000000000000000000000000000000000000001983 231.0
PYH2_k127_1900347_6 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000001601 203.0
PYH2_k127_1900347_7 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000000000000000001324 140.0
PYH2_k127_1905439_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.892e-289 903.0
PYH2_k127_1905439_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 548.0
PYH2_k127_1905439_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 520.0
PYH2_k127_1905439_3 Response regulator of the LytR AlgR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 407.0
PYH2_k127_1905439_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 382.0
PYH2_k127_1905439_5 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 369.0
PYH2_k127_1905439_6 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 327.0
PYH2_k127_1905439_7 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
PYH2_k127_1905439_8 membrane - - - 0.000000000000000000000000000000000000000000000000000000002113 209.0
PYH2_k127_1905439_9 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.000000000003169 68.0
PYH2_k127_1913633_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1283.0
PYH2_k127_1913633_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1014.0
PYH2_k127_1913633_10 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 331.0
PYH2_k127_1913633_11 cytochrome C oxidase K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 306.0
PYH2_k127_1913633_12 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 293.0
PYH2_k127_1913633_13 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001008 272.0
PYH2_k127_1913633_14 Electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001899 259.0
PYH2_k127_1913633_15 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000000000000000000000009191 240.0
PYH2_k127_1913633_16 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000003427 203.0
PYH2_k127_1913633_17 PFAM thioesterase superfamily protein K01075 - 3.1.2.23 0.00000000000000000000000000000000000000000000006277 178.0
PYH2_k127_1913633_18 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000000000000000000005723 161.0
PYH2_k127_1913633_19 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000003476 154.0
PYH2_k127_1913633_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 4.782e-198 623.0
PYH2_k127_1913633_20 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000001003 139.0
PYH2_k127_1913633_21 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000004414 131.0
PYH2_k127_1913633_22 Protein of unknown function (DUF2970) - - - 0.0000000000000000000003664 100.0
PYH2_k127_1913633_23 Protein of unknown function (DUF2909) - - - 0.00000000000000000001306 93.0
PYH2_k127_1913633_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 5.233e-195 616.0
PYH2_k127_1913633_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 490.0
PYH2_k127_1913633_5 Cytochrome c oxidase subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 482.0
PYH2_k127_1913633_6 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 469.0
PYH2_k127_1913633_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 465.0
PYH2_k127_1913633_8 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 430.0
PYH2_k127_1913633_9 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 419.0
PYH2_k127_194534_0 Elongation factor G, domain IV K02355 - - 0.0 1091.0
PYH2_k127_194534_1 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 1.267e-250 793.0
PYH2_k127_194534_10 monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000007807 192.0
PYH2_k127_194534_2 Magnesium transport protein CorA - - - 6.535e-241 760.0
PYH2_k127_194534_3 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 1.637e-228 713.0
PYH2_k127_194534_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.424e-226 729.0
PYH2_k127_194534_5 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 377.0
PYH2_k127_194534_6 Aldo/keto reductase family K00011 - 1.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 343.0
PYH2_k127_194534_7 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 305.0
PYH2_k127_194534_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001031 288.0
PYH2_k127_194534_9 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006494 254.0
PYH2_k127_1945714_0 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 435.0
PYH2_k127_1945714_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007692 363.0
PYH2_k127_1945714_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000966 279.0
PYH2_k127_1945714_3 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001113 258.0
PYH2_k127_1945714_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000001019 168.0
PYH2_k127_1954449_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 557.0
PYH2_k127_1954449_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 539.0
PYH2_k127_1954449_2 Amino-transferase class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 454.0
PYH2_k127_1954449_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 313.0
PYH2_k127_1954449_4 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 267.0
PYH2_k127_1954449_5 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000034 268.0
PYH2_k127_1954449_6 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001579 254.0
PYH2_k127_1954449_7 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000006236 191.0
PYH2_k127_1954449_8 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000000000004408 141.0
PYH2_k127_1958553_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 446.0
PYH2_k127_1958553_1 Lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 420.0
PYH2_k127_1958553_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 400.0
PYH2_k127_1958553_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 352.0
PYH2_k127_1958553_4 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 325.0
PYH2_k127_1958553_5 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000006501 193.0
PYH2_k127_197195_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 524.0
PYH2_k127_197195_1 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 405.0
PYH2_k127_197195_2 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000005853 235.0
PYH2_k127_197195_3 Dienelactone hydrolase - - - 0.000000000000000000000000000000000003091 141.0
PYH2_k127_1977258_0 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000001052 184.0
PYH2_k127_1977258_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000001796 115.0
PYH2_k127_1977258_2 Pfam:UPF0118 - - - 0.00000000002874 68.0
PYH2_k127_1977258_3 Phospholipid methyltransferase - - - 0.00000000003005 76.0
PYH2_k127_1977258_4 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0003332 53.0
PYH2_k127_2000809_0 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 1.931e-227 720.0
PYH2_k127_2000809_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 584.0
PYH2_k127_2000809_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 390.0
PYH2_k127_2000809_3 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.000000000000000000000000000000000000000001961 166.0
PYH2_k127_2000809_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000001156 67.0
PYH2_k127_2002316_0 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 500.0
PYH2_k127_2002316_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 337.0
PYH2_k127_2002316_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000679 108.0
PYH2_k127_2002316_3 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000004108 79.0
PYH2_k127_2023464_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.077e-233 726.0
PYH2_k127_2023464_1 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 458.0
PYH2_k127_2023464_2 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 346.0
PYH2_k127_2023464_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000002787 147.0
PYH2_k127_2023464_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000002654 96.0
PYH2_k127_2027973_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 419.0
PYH2_k127_2027973_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 411.0
PYH2_k127_2027973_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 323.0
PYH2_k127_2027973_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000003692 194.0
PYH2_k127_2027973_4 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0000000000000000000022 96.0
PYH2_k127_2027973_5 PFAM regulatory protein AsnC Lrp family K03719 - - 0.000000000000000000117 99.0
PYH2_k127_2027973_6 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.00000001265 57.0
PYH2_k127_2041344_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007793 250.0
PYH2_k127_2041344_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000004355 124.0
PYH2_k127_2041344_2 ABC transporter substrate binding protein - - - 0.00000001863 59.0
PYH2_k127_2053664_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 557.0
PYH2_k127_2053664_1 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 448.0
PYH2_k127_2053664_2 PFAM Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 333.0
PYH2_k127_2053664_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007589 244.0
PYH2_k127_2053664_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000005083 174.0
PYH2_k127_2053664_5 FtsX-like permease family K02004 - - 0.00000000000000000000005407 104.0
PYH2_k127_2053664_6 - - - - 0.0008146 43.0
PYH2_k127_2074064_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0 1059.0
PYH2_k127_2074064_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 2.657e-218 685.0
PYH2_k127_2074064_10 - - - - 0.0000000000000000000000002832 108.0
PYH2_k127_2074064_11 - - - - 0.000000000001557 78.0
PYH2_k127_2074064_12 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000005121 64.0
PYH2_k127_2074064_2 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 511.0
PYH2_k127_2074064_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 354.0
PYH2_k127_2074064_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005154 271.0
PYH2_k127_2074064_5 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005883 252.0
PYH2_k127_2074064_6 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007235 246.0
PYH2_k127_2074064_7 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000001854 226.0
PYH2_k127_2074064_8 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000002033 188.0
PYH2_k127_2074064_9 EamA-like transporter family - - - 0.00000000000000000000000000000000222 130.0
PYH2_k127_2082077_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 440.0
PYH2_k127_2082077_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 417.0
PYH2_k127_2082077_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 408.0
PYH2_k127_2082077_3 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000005951 72.0
PYH2_k127_2082729_0 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 492.0
PYH2_k127_2082729_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 445.0
PYH2_k127_2082729_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 420.0
PYH2_k127_2082729_3 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
PYH2_k127_2082729_4 Amino-transferase class IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 347.0
PYH2_k127_2082729_5 Hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000009281 204.0
PYH2_k127_2082729_6 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000001016 209.0
PYH2_k127_2082729_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000005664 184.0
PYH2_k127_2082729_8 Cupin domain - - - 0.000000000000000000000000000000000000000000003288 183.0
PYH2_k127_2082729_9 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000001431 112.0
PYH2_k127_2090988_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.653e-303 945.0
PYH2_k127_2090988_1 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 541.0
PYH2_k127_2090988_2 PFAM Pyruvate carboxyltransferase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 499.0
PYH2_k127_2090988_3 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009006 276.0
PYH2_k127_2090988_4 YbaK prolyl-tRNA synthetase associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005569 254.0
PYH2_k127_2090988_5 d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000004845 223.0
PYH2_k127_2090988_6 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000000000527 160.0
PYH2_k127_2090988_7 Protein of unknown function (DUF1289) K06938 - - 0.0000000000000002215 90.0
PYH2_k127_2091262_0 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 421.0
PYH2_k127_2091262_1 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 302.0
PYH2_k127_2091262_2 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000225 156.0
PYH2_k127_2091262_3 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000002884 149.0
PYH2_k127_2091262_4 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000344 92.0
PYH2_k127_2091262_5 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000006072 76.0
PYH2_k127_211437_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 504.0
PYH2_k127_211437_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 358.0
PYH2_k127_211437_2 ThiF family K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 351.0
PYH2_k127_211437_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 310.0
PYH2_k127_211437_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000001599 170.0
PYH2_k127_211437_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000001671 136.0
PYH2_k127_2173131_0 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 389.0
PYH2_k127_2173131_1 HI0933-like protein - - - 0.00000000000000000000000000000000000000000000000000003816 196.0
PYH2_k127_2185931_0 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 516.0
PYH2_k127_2185931_1 Flotillin K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 355.0
PYH2_k127_2185931_2 threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000001145 141.0
PYH2_k127_2185931_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000002782 83.0
PYH2_k127_2185931_4 Glutathione S-transferase, C-terminal domain - - - 0.00000000000014 75.0
PYH2_k127_2185931_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000001096 68.0
PYH2_k127_2207817_0 AMP-binding enzyme K01895 - 6.2.1.1 6.031e-264 825.0
PYH2_k127_2207817_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 5.212e-201 628.0
PYH2_k127_2207817_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006684 414.0
PYH2_k127_2207817_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005738 244.0
PYH2_k127_2207817_4 HAD-hyrolase-like - - - 0.000000000000000002914 98.0
PYH2_k127_2207817_5 cellulase activity - - - 0.00000000000003825 85.0
PYH2_k127_2224431_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 3.727e-279 872.0
PYH2_k127_2224431_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000003504 158.0
PYH2_k127_2233135_0 peptidase U62, modulator of DNA gyrase K03592 - - 8.76e-228 717.0
PYH2_k127_2233135_1 Belongs to the UPF0307 family K09889 - - 0.0000000000000009228 79.0
PYH2_k127_2237191_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 531.0
PYH2_k127_2237191_1 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 284.0
PYH2_k127_2237191_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000009105 149.0
PYH2_k127_2237191_3 PFAM binding-protein-dependent transport systems inner membrane component K05773,K06857 - 3.6.3.55 0.0000000000000000000000003196 106.0
PYH2_k127_2240951_0 carbohydrate binding K13688 - - 3.785e-218 696.0
PYH2_k127_2240951_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 295.0
PYH2_k127_2240951_2 - - - - 0.000000000000000000001855 95.0
PYH2_k127_2240951_3 GGDEF domain' - - - 0.0000000002315 70.0
PYH2_k127_2260896_0 Participates in both transcription termination and antitermination K02600 - - 3.656e-270 837.0
PYH2_k127_2260896_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000001815 201.0
PYH2_k127_2264404_0 Belongs to the IlvD Edd family K01687,K13875,K22186 - 4.2.1.25,4.2.1.82,4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 549.0
PYH2_k127_2264404_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 473.0
PYH2_k127_2264404_2 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 379.0
PYH2_k127_2277505_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 3.404e-258 803.0
PYH2_k127_2277505_1 DctM subunit - - - 1.428e-213 674.0
PYH2_k127_2277505_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000007271 198.0
PYH2_k127_2277505_11 tryptophan synthase subunit beta - - - 0.000000000000000000000000000000000002215 142.0
PYH2_k127_2277505_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 530.0
PYH2_k127_2277505_3 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 520.0
PYH2_k127_2277505_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 412.0
PYH2_k127_2277505_5 Uroporphyrin-III C-methyltransferase K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 345.0
PYH2_k127_2277505_6 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 319.0
PYH2_k127_2277505_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 306.0
PYH2_k127_2277505_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 301.0
PYH2_k127_2277505_9 Ankyrin repeats (3 copies) K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000001372 245.0
PYH2_k127_2284553_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 537.0
PYH2_k127_2284553_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 353.0
PYH2_k127_2284553_10 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000004551 175.0
PYH2_k127_2284553_11 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000004008 136.0
PYH2_k127_2284553_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 347.0
PYH2_k127_2284553_3 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 322.0
PYH2_k127_2284553_4 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 288.0
PYH2_k127_2284553_5 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003284 241.0
PYH2_k127_2284553_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000003081 240.0
PYH2_k127_2284553_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000008551 242.0
PYH2_k127_2284553_8 TM2 domain - - - 0.0000000000000000000000000000000000000000000000000000000009688 204.0
PYH2_k127_2284553_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000003653 203.0
PYH2_k127_2289731_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000003379 271.0
PYH2_k127_2289731_1 glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000254 214.0
PYH2_k127_2289731_2 PIN domain - - - 0.00000000000000000000000000000000000002139 151.0
PYH2_k127_2289731_3 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000004787 118.0
PYH2_k127_2289731_4 - - - - 0.0000000000000000000008904 97.0
PYH2_k127_2289731_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00004358 55.0
PYH2_k127_229001_0 Aminotransferase class-III K00823 - 2.6.1.19 2.027e-197 629.0
PYH2_k127_229001_1 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 467.0
PYH2_k127_229001_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 471.0
PYH2_k127_229001_3 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 354.0
PYH2_k127_229001_4 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004171 272.0
PYH2_k127_229001_5 D-alanyl-D-alanine carboxypeptidase K01286,K07262 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000006424 255.0
PYH2_k127_2330242_0 carboxylase K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 8.204e-228 713.0
PYH2_k127_2330242_1 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000004885 109.0
PYH2_k127_2334751_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0 1013.0
PYH2_k127_2334751_1 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000000000000000000000000000731 243.0
PYH2_k127_2334751_2 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000007176 223.0
PYH2_k127_2334751_3 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000004024 134.0
PYH2_k127_2391254_0 Putative heavy-metal chelation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 344.0
PYH2_k127_2391254_1 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000212 151.0
PYH2_k127_2391254_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000001288 134.0
PYH2_k127_2391254_3 lipoate-protein ligase A - - - 0.000000000001598 69.0
PYH2_k127_2461793_0 Sulfate permease family - - - 1.312e-299 927.0
PYH2_k127_2461793_1 Arginine K01478 - 3.5.3.6 1.681e-202 637.0
PYH2_k127_2461793_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K13252 - 2.1.3.3,2.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 603.0
PYH2_k127_2461793_3 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 565.0
PYH2_k127_2461793_4 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 485.0
PYH2_k127_2461793_5 Ion channel - - - 0.0000000000000000000000003768 109.0
PYH2_k127_2461793_6 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000002404 104.0
PYH2_k127_2464617_0 NAD(P)H quinone oxidoreductase, PIG3 family K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 473.0
PYH2_k127_2464617_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 394.0
PYH2_k127_2464617_2 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000109 126.0
PYH2_k127_2467449_0 protein kinase activity - - - 0.000000000000000000000000000000000000000002068 173.0
PYH2_k127_2467449_1 FAD binding domain K00480 - 1.14.13.1 0.00002068 48.0
PYH2_k127_2482388_0 Threonine synthase K01733 - 4.2.3.1 4.316e-237 741.0
PYH2_k127_2482388_1 homoserine dehydrogenase K00003 - 1.1.1.3 2.431e-227 710.0
PYH2_k127_2482388_2 PFAM Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 602.0
PYH2_k127_2482388_3 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 533.0
PYH2_k127_2482388_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002607 254.0
PYH2_k127_2482388_5 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000002989 200.0
PYH2_k127_2482388_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000003754 111.0
PYH2_k127_2496436_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 2.983e-241 754.0
PYH2_k127_2496436_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 6.581e-218 686.0
PYH2_k127_2496436_2 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 529.0
PYH2_k127_2496436_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 383.0
PYH2_k127_2496436_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 303.0
PYH2_k127_2496436_5 - - - - 0.000000000000002932 88.0
PYH2_k127_2518735_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.208e-200 630.0
PYH2_k127_2518735_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.412e-197 620.0
PYH2_k127_2526785_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1591.0
PYH2_k127_2526785_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 496.0
PYH2_k127_2526785_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 447.0
PYH2_k127_2526785_3 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 368.0
PYH2_k127_2526785_4 PFAM helix-turn-helix, Fis-type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 369.0
PYH2_k127_2526785_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000000003493 254.0
PYH2_k127_2526785_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000000006198 179.0
PYH2_k127_2526785_7 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000002586 138.0
PYH2_k127_2526785_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000001236 126.0
PYH2_k127_2526785_9 PFAM SpoVT AbrB K07172,K18829 - - 0.0000000000000000000000005833 113.0
PYH2_k127_2530937_0 ATPase family associated with various cellular activities (AAA) - - - 0.0 1153.0
PYH2_k127_2530937_1 Diguanylate cyclase K21023 - 2.7.7.65 1.141e-202 653.0
PYH2_k127_2530937_2 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 570.0
PYH2_k127_2530937_3 Fumarylacetoacetate (Faa) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 541.0
PYH2_k127_2530937_4 PFAM GumN family protein K09973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005638 271.0
PYH2_k127_2530937_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001251 220.0
PYH2_k127_2530937_6 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000007132 185.0
PYH2_k127_2530937_7 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000000000000000000000000000000001564 175.0
PYH2_k127_2530937_8 Protein of unknown function (DUF3567) - - - 0.00000000000000000000000003384 111.0
PYH2_k127_2530937_9 chlorophyll binding - - - 0.0000000000000000000000008666 112.0
PYH2_k127_2531683_0 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 3.41e-198 626.0
PYH2_k127_2531683_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 507.0
PYH2_k127_2531683_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000004354 166.0
PYH2_k127_2531683_3 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000003213 120.0
PYH2_k127_2531683_4 Sigma-54 interaction domain K02584 - - 0.0000000004903 67.0
PYH2_k127_2531683_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000601 43.0
PYH2_k127_2533508_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.576e-253 786.0
PYH2_k127_2533508_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 601.0
PYH2_k127_2533508_2 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 593.0
PYH2_k127_2533508_3 Peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 381.0
PYH2_k127_2533508_4 Haloacid dehalogenase-like hydrolase K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003193 261.0
PYH2_k127_2533508_5 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001324 252.0
PYH2_k127_253399_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 545.0
PYH2_k127_253399_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000001228 223.0
PYH2_k127_2534904_0 Monosaccharide ABC transporter ATP-binding protein, CUT2 family K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 528.0
PYH2_k127_2534904_1 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 377.0
PYH2_k127_2534904_2 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000000004062 196.0
PYH2_k127_2534904_3 Histidine kinase - - - 0.00000000000000000000000000000000000001047 153.0
PYH2_k127_2534904_4 Cupin 2, conserved barrel K21700 - - 0.00000000000000000000000000000001337 128.0
PYH2_k127_253867_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 562.0
PYH2_k127_253867_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000003799 250.0
PYH2_k127_253867_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
PYH2_k127_2561127_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 466.0
PYH2_k127_2561127_1 L-asparaginase II - - - 0.0000000000000000000000000000003682 128.0
PYH2_k127_2561989_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 378.0
PYH2_k127_2561989_1 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 314.0
PYH2_k127_2561989_2 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000557 196.0
PYH2_k127_2561989_3 Belongs to the 'phage' integrase family - - - 0.0000002199 52.0
PYH2_k127_2567072_0 ribonuclease, Rne Rng family K08301 - - 5.434e-256 802.0
PYH2_k127_2567072_1 family 9 K02849 - - 0.0000000000000000000000000000000000006585 145.0
PYH2_k127_2567072_2 Maf-like protein K06287 - - 0.00000000000000000000000000000005919 126.0
PYH2_k127_2587499_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 6.071e-317 978.0
PYH2_k127_2587499_1 Cytochrome D1 heme domain K19345 - - 1.699e-198 628.0
PYH2_k127_2587499_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 323.0
PYH2_k127_2587499_3 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.00000000000000000000000000000000000001881 146.0
PYH2_k127_2587499_4 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000004247 134.0
PYH2_k127_2587499_5 COG1522 Transcriptional regulators - - - 0.00000000004076 68.0
PYH2_k127_2596477_0 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000005762 237.0
PYH2_k127_2596477_1 import inner membrane translocase subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000008709 192.0
PYH2_k127_2596477_2 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000573 160.0
PYH2_k127_2639565_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1897.0
PYH2_k127_2639565_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 1.157e-259 804.0
PYH2_k127_2639565_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000007414 166.0
PYH2_k127_2639565_11 - - - - 0.00000000000000000000000000000000000000000007075 169.0
PYH2_k127_2639565_12 Transglycosylase associated protein - - - 0.00000000000000000000000000005784 119.0
PYH2_k127_2639565_13 Histone family protein nucleoid-structuring protein H-NS K03746 - - 0.00000000000000000000000000007933 119.0
PYH2_k127_2639565_14 - - - - 0.000000001348 69.0
PYH2_k127_2639565_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.257e-231 725.0
PYH2_k127_2639565_3 GGDEF domain - - - 8.443e-209 674.0
PYH2_k127_2639565_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.177e-204 645.0
PYH2_k127_2639565_5 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 559.0
PYH2_k127_2639565_6 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 520.0
PYH2_k127_2639565_7 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 419.0
PYH2_k127_2639565_8 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 305.0
PYH2_k127_2639565_9 protein domain associated with - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004976 240.0
PYH2_k127_2643080_0 KR domain K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 286.0
PYH2_k127_2643080_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008716 277.0
PYH2_k127_2643080_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000002041 125.0
PYH2_k127_265794_0 KR domain K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 364.0
PYH2_k127_265794_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 330.0
PYH2_k127_265794_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000002104 201.0
PYH2_k127_265794_3 PFAM NAD-dependent epimerase dehydratase K22025 - 1.1.1.410 0.00000000000000000000006392 99.0
PYH2_k127_2712108_0 ABC transporter, ATP-binding protein K18893 - - 2.109e-301 948.0
PYH2_k127_2712108_1 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 335.0
PYH2_k127_2712108_2 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 311.0
PYH2_k127_2723708_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000001608 230.0
PYH2_k127_2723708_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000004227 175.0
PYH2_k127_2723708_2 response regulator - - - 0.00000000000000000000000000000000000004317 153.0
PYH2_k127_2731961_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 1.63e-315 983.0
PYH2_k127_2731961_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.645e-198 633.0
PYH2_k127_2731961_2 [2Fe-2S] binding domain K04107 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000002126 234.0
PYH2_k127_2731961_3 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000000000000871 75.0
PYH2_k127_2731961_4 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000002996 64.0
PYH2_k127_2742097_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 494.0
PYH2_k127_2742097_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000004593 205.0
PYH2_k127_274215_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5.42e-197 616.0
PYH2_k127_274215_1 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 606.0
PYH2_k127_274215_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 553.0
PYH2_k127_274215_3 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000001006 76.0
PYH2_k127_2772617_0 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 476.0
PYH2_k127_2772617_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 389.0
PYH2_k127_2772617_2 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.000000000000000000000000000000000000000000004582 183.0
PYH2_k127_2772617_3 Protein of unknown function DUF86 - - - 0.000000000000000000000000004887 113.0
PYH2_k127_2803460_0 Uncharacterised signal transduction histidine kinase domain (DUF2222) K07678 - 2.7.13.3 2.058e-285 916.0
PYH2_k127_2803460_1 permease K07089 - - 1.349e-232 727.0
PYH2_k127_2803460_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 458.0
PYH2_k127_2803460_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000001488 157.0
PYH2_k127_2803460_4 Thioredoxin domain - - - 0.0000000000000000000000000000000000002175 141.0
PYH2_k127_2806048_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 436.0
PYH2_k127_2806048_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
PYH2_k127_2806048_2 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000000000000004591 223.0
PYH2_k127_2806048_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000149 76.0
PYH2_k127_2806048_4 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 0.000000000003169 68.0
PYH2_k127_2810001_0 Peptidase family M20/M25/M40 K05831 - - 1.184e-244 758.0
PYH2_k127_2810001_1 PERMEase K06901 - - 6.197e-226 711.0
PYH2_k127_2810001_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 1.867e-212 681.0
PYH2_k127_2810001_3 carbamoyltransferase YgeW - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 1.944e-208 653.0
PYH2_k127_2810001_4 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006779 248.0
PYH2_k127_2810001_6 - - - - 0.0000000000000007404 82.0
PYH2_k127_2815132_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 450.0
PYH2_k127_2815132_1 Histidine kinase K20976 - - 0.00000000000000000000009514 101.0
PYH2_k127_2815132_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000004481 78.0
PYH2_k127_2816081_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 547.0
PYH2_k127_2816081_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 449.0
PYH2_k127_2816081_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000002013 174.0
PYH2_k127_2816081_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000002128 131.0
PYH2_k127_2843305_0 Diguanylate cyclase - - - 1.525e-279 876.0
PYH2_k127_2843305_1 Flagellar motor switch K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 535.0
PYH2_k127_2843305_10 PFAM TonB-dependent receptor, beta-barrel K02014 - - 0.000000000000000000000000004194 120.0
PYH2_k127_2843305_11 - - - - 0.0000003356 57.0
PYH2_k127_2843305_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 374.0
PYH2_k127_2843305_3 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 327.0
PYH2_k127_2843305_4 Flagellar motor switch protein fliN K02417,K03225 - - 0.000000000000000000000000000000000000000000000000000000000000000244 223.0
PYH2_k127_2843305_5 diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000002871 230.0
PYH2_k127_2843305_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000001828 194.0
PYH2_k127_2843305_7 Role in flagellar biosynthesis K02420 - - 0.00000000000000000000000000000000006087 137.0
PYH2_k127_2843305_8 PFAM GYD family protein - - - 0.000000000000000000000000000001862 122.0
PYH2_k127_2843305_9 Flagellar biosynthesis protein, FliO K02418 - - 0.000000000000000000000000001248 115.0
PYH2_k127_2846091_0 PQQ enzyme repeat - - - 3.023e-301 930.0
PYH2_k127_2846091_1 Ankyrin repeats (3 copies) K06867,K21440 - - 0.0000000000000000000000000000000000000000003438 171.0
PYH2_k127_2846091_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000002245 74.0
PYH2_k127_2860243_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 7.324e-299 930.0
PYH2_k127_2860243_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006334 246.0
PYH2_k127_2860243_2 ABC transporter K05779 - - 0.0000000000000000000001381 99.0
PYH2_k127_2865071_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1031.0
PYH2_k127_2865071_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 510.0
PYH2_k127_2865071_2 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 456.0
PYH2_k127_2865071_3 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 381.0
PYH2_k127_2865071_4 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 323.0
PYH2_k127_2865071_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 300.0
PYH2_k127_2865071_6 Cytochrome c - - - 0.000000000000000000000001976 110.0
PYH2_k127_2865843_0 FAD dependent oxidoreductase - - - 0.0 1049.0
PYH2_k127_2865843_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000035 258.0
PYH2_k127_2865843_2 YXWGXW repeat (2 copies) - - - 0.000000000000000000000000000012 121.0
PYH2_k127_2865843_3 membrane transporter protein K07090 - - 0.000000000000000000008563 94.0
PYH2_k127_2881024_0 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 7.623e-205 639.0
PYH2_k127_2881024_1 Transketolase, C-terminal domain K21417 - - 2.826e-203 635.0
PYH2_k127_2881024_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 505.0
PYH2_k127_2881024_3 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 403.0
PYH2_k127_2881024_4 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 395.0
PYH2_k127_2881024_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 332.0
PYH2_k127_2881024_6 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000473 277.0
PYH2_k127_2881024_7 Biotin-requiring enzyme - - - 0.0000000000000000000000000000002377 127.0
PYH2_k127_2881024_9 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0006343 43.0
PYH2_k127_2886248_0 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 9.031e-260 812.0
PYH2_k127_2886248_1 ABC transporter substrate binding protein - - - 0.00000000000000000002618 91.0
PYH2_k127_2886477_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1122.0
PYH2_k127_2886477_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 618.0
PYH2_k127_2886477_2 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000000000007664 199.0
PYH2_k127_2886477_3 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000721 141.0
PYH2_k127_2889314_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.211e-264 825.0
PYH2_k127_2889314_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 5.144e-225 719.0
PYH2_k127_2889314_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000007183 255.0
PYH2_k127_2889314_11 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000000000000000000000008865 204.0
PYH2_k127_2889314_12 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000001197 200.0
PYH2_k127_2889314_13 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000000000000000000000000000000000000000000000002694 188.0
PYH2_k127_2889314_14 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000000000000000003237 132.0
PYH2_k127_2889314_15 - - - - 0.000000000000000512 79.0
PYH2_k127_2889314_16 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0008741 42.0
PYH2_k127_2889314_2 Male sterility protein - - - 4.86e-220 690.0
PYH2_k127_2889314_3 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 565.0
PYH2_k127_2889314_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 539.0
PYH2_k127_2889314_5 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 523.0
PYH2_k127_2889314_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 512.0
PYH2_k127_2889314_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 423.0
PYH2_k127_2889314_8 PFAM phospholipid glycerol acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 339.0
PYH2_k127_2889314_9 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 284.0
PYH2_k127_2903451_0 AMP-binding enzyme C-terminal domain K00666 - - 7.337e-272 850.0
PYH2_k127_2903451_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 479.0
PYH2_k127_2903451_2 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 287.0
PYH2_k127_2903451_3 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
PYH2_k127_2903451_4 Ecotin K08276 - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
PYH2_k127_2903451_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000001066 239.0
PYH2_k127_2903451_6 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000001088 189.0
PYH2_k127_2903451_7 Plasmid stabilization system K19092 - - 0.0000000000000000000000000000009749 123.0
PYH2_k127_2903451_8 Ribbon-helix-helix protein, copG family - - - 0.000000000000000001285 93.0
PYH2_k127_2903451_9 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000001827 63.0
PYH2_k127_2912526_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.55e-300 936.0
PYH2_k127_2912526_1 peptidylprolyl isomerase K03770 - 5.2.1.8 2.748e-228 724.0
PYH2_k127_2912526_2 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 435.0
PYH2_k127_2912526_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 368.0
PYH2_k127_2912526_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 338.0
PYH2_k127_2912526_5 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 332.0
PYH2_k127_2912526_6 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000002191 256.0
PYH2_k127_2912526_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000004262 205.0
PYH2_k127_2912526_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000007083 171.0
PYH2_k127_2912526_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000003885 154.0
PYH2_k127_2924258_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K03852 - 2.3.3.15 6.9e-272 848.0
PYH2_k127_2924258_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 485.0
PYH2_k127_2924258_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 390.0
PYH2_k127_2924258_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
PYH2_k127_2934647_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 6.532e-242 765.0
PYH2_k127_2934647_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 347.0
PYH2_k127_2934647_2 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000002104 166.0
PYH2_k127_2962730_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 561.0
PYH2_k127_2962730_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 514.0
PYH2_k127_2962730_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 458.0
PYH2_k127_2962730_3 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
PYH2_k127_2962730_4 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 389.0
PYH2_k127_2971721_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 2.383e-198 626.0
PYH2_k127_2971721_1 RNA polymerase sigma K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 456.0
PYH2_k127_2971721_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 398.0
PYH2_k127_2971721_3 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 294.0
PYH2_k127_2971721_4 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000208 219.0
PYH2_k127_2972683_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 1.037e-203 639.0
PYH2_k127_2972683_1 Major Facilitator Superfamily K19577 - - 0.000000000000000000000000000000000000000000000000001224 188.0
PYH2_k127_2972683_2 membrane - - - 0.0000000000000000000000000000000000000000000229 164.0
PYH2_k127_2973336_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 1.475e-239 752.0
PYH2_k127_2973336_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 342.0
PYH2_k127_2973336_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001579 255.0
PYH2_k127_2973336_3 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000001953 192.0
PYH2_k127_2973336_4 Peptidase S24-like - - - 0.0000000000000000000000000000000000000000001077 175.0
PYH2_k127_2973336_5 Cas6 Crispr - - - 0.000000000000000000000000000000000001179 140.0
PYH2_k127_2973336_6 - - - - 0.00000000000000000002646 93.0
PYH2_k127_2980326_0 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 575.0
PYH2_k127_2980326_1 Protein of unknown function (DUF3717) K06938 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001242 245.0
PYH2_k127_2980326_2 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005327 253.0
PYH2_k127_2980326_3 glyoxalase bleomycin resistance protein dioxygenase K06996 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000323 166.0
PYH2_k127_2980326_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000009116 85.0
PYH2_k127_2980429_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 3.564e-244 759.0
PYH2_k127_2980429_1 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 583.0
PYH2_k127_2980429_10 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 293.0
PYH2_k127_2980429_11 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001086 270.0
PYH2_k127_2980429_12 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001755 243.0
PYH2_k127_2980429_13 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002043 243.0
PYH2_k127_2980429_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000008937 163.0
PYH2_k127_2980429_15 YCII-related domain K05527,K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000914 136.0
PYH2_k127_2980429_16 Major Facilitator Superfamily - - - 0.000000000000000001779 87.0
PYH2_k127_2980429_17 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000006382 78.0
PYH2_k127_2980429_18 PFAM regulatory protein, MarR - - - 0.000000005419 57.0
PYH2_k127_2980429_19 Stress responsive alpha-beta barrel - - - 0.00000006736 56.0
PYH2_k127_2980429_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 526.0
PYH2_k127_2980429_20 SnoaL-like domain - - - 0.0000006704 57.0
PYH2_k127_2980429_21 Protein conserved in bacteria - - - 0.0000007445 57.0
PYH2_k127_2980429_3 Superoxide dismutase K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 497.0
PYH2_k127_2980429_4 PFAM intradiol ring-cleavage dioxygenase K03381,K04098,K15253 - 1.13.11.1,1.13.11.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 377.0
PYH2_k127_2980429_5 Zn-dependent hydrolases including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 372.0
PYH2_k127_2980429_6 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 367.0
PYH2_k127_2980429_7 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 363.0
PYH2_k127_2980429_8 (ABC) transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 318.0
PYH2_k127_2980429_9 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 306.0
PYH2_k127_2990173_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 571.0
PYH2_k127_2990173_1 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 308.0
PYH2_k127_2990173_2 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004606 277.0
PYH2_k127_2990173_3 cellulase activity - - - 0.0000000000000000000000000000000000000000000001671 186.0
PYH2_k127_2992413_0 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 577.0
PYH2_k127_2992413_1 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 448.0
PYH2_k127_2992413_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 315.0
PYH2_k127_2992413_3 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000000005086 87.0
PYH2_k127_3003563_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 1.119e-214 696.0
PYH2_k127_3003563_1 binding-protein-dependent transport systems inner membrane component K02011 - - 4.548e-213 673.0
PYH2_k127_3003563_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 467.0
PYH2_k127_3003563_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 411.0
PYH2_k127_3003563_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 388.0
PYH2_k127_3003563_5 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 351.0
PYH2_k127_3003563_6 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 361.0
PYH2_k127_3003563_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000206 259.0
PYH2_k127_3003563_8 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000461 213.0
PYH2_k127_3003563_9 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000007554 189.0
PYH2_k127_3020945_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 494.0
PYH2_k127_3020945_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 338.0
PYH2_k127_3020945_2 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000004229 238.0
PYH2_k127_3020945_3 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006748 231.0
PYH2_k127_3020945_4 HupE / UreJ protein - - - 0.00000000000000000000000000000004502 141.0
PYH2_k127_3020945_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000009268 94.0
PYH2_k127_3020945_6 Gaf domain K08968 - 1.8.4.14 0.000000000000193 72.0
PYH2_k127_3020945_7 Protein of unknown function (DUF3604) - - - 0.00000000001457 64.0
PYH2_k127_3031329_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1057.0
PYH2_k127_3031329_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.416e-270 837.0
PYH2_k127_3031329_10 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.000000000006335 66.0
PYH2_k127_3031329_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 8.995e-229 717.0
PYH2_k127_3031329_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 6.372e-197 617.0
PYH2_k127_3031329_4 FAD linked oxidases, C-terminal domain - - - 4.457e-196 618.0
PYH2_k127_3031329_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 311.0
PYH2_k127_3031329_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000176 267.0
PYH2_k127_3031329_7 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001961 255.0
PYH2_k127_3031329_8 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000000000000001135 186.0
PYH2_k127_3031329_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000001926 176.0
PYH2_k127_3039278_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 577.0
PYH2_k127_3039278_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002809 247.0
PYH2_k127_3039278_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000003852 158.0
PYH2_k127_3039444_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000001168 148.0
PYH2_k127_3039444_1 Mammalian cell entry related domain protein K02067 - - 0.00003845 55.0
PYH2_k127_3039444_2 Transcriptional regulatory protein, C terminal - - - 0.0003166 44.0
PYH2_k127_3042296_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000003635 222.0
PYH2_k127_3042296_1 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000000000000000001235 190.0
PYH2_k127_3042296_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000003526 117.0
PYH2_k127_3046620_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.164e-218 687.0
PYH2_k127_3046620_1 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 446.0
PYH2_k127_3046620_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 413.0
PYH2_k127_3049488_0 PFAM Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 485.0
PYH2_k127_3049488_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 443.0
PYH2_k127_3049488_2 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000000000000000000000000008244 216.0
PYH2_k127_3049488_4 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000001225 113.0
PYH2_k127_3049488_5 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 GO:0000166,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0003842,GO:0004657,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006355,GO:0006520,GO:0006536,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009889,GO:0009890,GO:0009892,GO:0009898,GO:0009987,GO:0010133,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043565,GO:0043648,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0048519,GO:0048523,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0098552,GO:0098562,GO:0140110,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 1.2.1.88,1.5.5.2 0.00000002999 59.0
PYH2_k127_3054853_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 3.43e-287 893.0
PYH2_k127_3054853_1 AMP-binding enzyme K12508 - 6.2.1.34 3.696e-271 862.0
PYH2_k127_3054853_10 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 367.0
PYH2_k127_3054853_11 Enoyl-CoA hydratase/isomerase K20036 - 4.2.1.155 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 391.0
PYH2_k127_3054853_12 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000001016 208.0
PYH2_k127_3054853_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000001045 202.0
PYH2_k127_3054853_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000006414 143.0
PYH2_k127_3054853_15 Amidohydrolase K07045 - - 0.00000000000000000000000000003657 118.0
PYH2_k127_3054853_16 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0007427 42.0
PYH2_k127_3054853_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 9.163e-223 700.0
PYH2_k127_3054853_3 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101,K00104 - 1.1.2.3,1.1.3.15 1.26e-205 646.0
PYH2_k127_3054853_4 COG0246 Mannitol-1-phosphate altronate dehydrogenases K00040 - 1.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 571.0
PYH2_k127_3054853_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 548.0
PYH2_k127_3054853_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 530.0
PYH2_k127_3054853_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 518.0
PYH2_k127_3054853_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 402.0
PYH2_k127_3054853_9 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K08323 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 395.0
PYH2_k127_3062463_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 575.0
PYH2_k127_3062463_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 505.0
PYH2_k127_3062463_2 belongs to the aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.00000000263 61.0
PYH2_k127_3068413_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 1.093e-238 743.0
PYH2_k127_3068413_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 591.0
PYH2_k127_3068413_2 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 533.0
PYH2_k127_3068413_3 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 398.0
PYH2_k127_3068413_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000003254 200.0
PYH2_k127_3068413_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000005928 153.0
PYH2_k127_3068413_6 oxidase, subunit K00426 - 1.10.3.14 0.000000001593 59.0
PYH2_k127_3068413_7 Flavinator of succinate dehydrogenase K09159 - - 0.0004857 43.0
PYH2_k127_3072799_0 cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 495.0
PYH2_k127_3072799_1 Uncharacterised protein family (UPF0149) K07039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002627 252.0
PYH2_k127_3093087_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1833.0
PYH2_k127_3093087_1 Formate dehydrogenase gamma subunit K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 502.0
PYH2_k127_3093087_10 - - - - 0.00000000000001784 79.0
PYH2_k127_3093087_11 - - - - 0.00000000000004698 74.0
PYH2_k127_3093087_2 4Fe-4S dicluster domain K00124,K07307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 423.0
PYH2_k127_3093087_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 428.0
PYH2_k127_3093087_4 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 380.0
PYH2_k127_3093087_5 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 297.0
PYH2_k127_3093087_6 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000000000000000000000000000000000583 226.0
PYH2_k127_3093087_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000102 201.0
PYH2_k127_3093087_8 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000003013 109.0
PYH2_k127_3093087_9 - - - - 0.000000000000000000000009639 110.0
PYH2_k127_3122572_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 334.0
PYH2_k127_3122572_1 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
PYH2_k127_3122572_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000004147 183.0
PYH2_k127_3122572_3 ACT domain - - - 0.000000000000000000001336 100.0
PYH2_k127_3122572_4 AlkA N-terminal domain K13529 - 3.2.2.21 0.00000000000000000002897 91.0
PYH2_k127_3126278_0 phosphate-selective porin O and P - - - 3.411e-218 686.0
PYH2_k127_3126278_1 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 528.0
PYH2_k127_3126278_2 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000001156 247.0
PYH2_k127_3126278_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000003107 128.0
PYH2_k127_3140165_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 489.0
PYH2_k127_3140165_1 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 464.0
PYH2_k127_3154023_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 458.0
PYH2_k127_3154023_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 462.0
PYH2_k127_3154023_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 345.0
PYH2_k127_3154023_3 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000004571 245.0
PYH2_k127_3154023_4 Tetratricopeptide repeat K12284 - - 0.0000000000000000000000009884 112.0
PYH2_k127_3162381_0 PFAM carboxyl transferase K01615 - 4.1.1.70 2.101e-292 911.0
PYH2_k127_3162381_1 PFAM AMP-dependent synthetase and ligase K08295 - 6.2.1.32 5.683e-283 877.0
PYH2_k127_3162381_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000001786 232.0
PYH2_k127_3162381_11 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001987 212.0
PYH2_k127_3162381_12 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.000000000000000000000000000000000000000000000000004005 184.0
PYH2_k127_3162381_13 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000000003043 143.0
PYH2_k127_3162381_14 Biotin-requiring enzyme - - - 0.00000000000000002255 84.0
PYH2_k127_3162381_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000005364 80.0
PYH2_k127_3162381_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0001912 48.0
PYH2_k127_3162381_2 acyl-CoA dehydrogenase K00252 - 1.3.8.6 3.132e-231 720.0
PYH2_k127_3162381_3 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 586.0
PYH2_k127_3162381_4 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 550.0
PYH2_k127_3162381_5 hydrolase of the alpha K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 476.0
PYH2_k127_3162381_6 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005062 281.0
PYH2_k127_3162381_7 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000005597 266.0
PYH2_k127_3162381_8 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003259 261.0
PYH2_k127_3162381_9 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003375 246.0
PYH2_k127_3164814_0 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 388.0
PYH2_k127_3164814_1 Glyoxalase-like domain - - - 0.000000000000000000000000000000003992 134.0
PYH2_k127_3164814_2 EamA-like transporter family - - - 0.00000000000000000001973 91.0
PYH2_k127_3164814_3 AraC-like ligand binding domain - - - 0.0000000000005695 70.0
PYH2_k127_3164814_4 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.0002045 45.0
PYH2_k127_3180339_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 2.14e-223 698.0
PYH2_k127_3180339_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000002214 253.0
PYH2_k127_3196994_0 Guanine deaminase K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 600.0
PYH2_k127_3196994_1 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 519.0
PYH2_k127_3212351_0 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009826 253.0
PYH2_k127_3212351_1 - - - - 0.0000000000000001602 88.0
PYH2_k127_3212351_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000003288 66.0
PYH2_k127_3212868_0 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 314.0
PYH2_k127_3212868_1 Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000000001088 190.0
PYH2_k127_3212868_2 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000007893 186.0
PYH2_k127_3212868_3 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000000004156 158.0
PYH2_k127_3229550_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 557.0
PYH2_k127_3229550_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000003239 115.0
PYH2_k127_3239384_0 Amidohydrolase family - - - 1.416e-237 748.0
PYH2_k127_3239384_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 583.0
PYH2_k127_3239384_2 PFAM cobalamin synthesis protein P47K - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 304.0
PYH2_k127_3239384_3 Sulfite exporter TauE/SafE - - - 0.000000000000000000000002892 107.0
PYH2_k127_3256670_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 435.0
PYH2_k127_3256670_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 323.0
PYH2_k127_3256670_2 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000001785 190.0
PYH2_k127_3256670_3 Protein of unknown function (DUF1439) - - - 0.00000000000000000000000000004622 122.0
PYH2_k127_3263884_0 exporters of the RND superfamily K07003 - - 0.0 1256.0
PYH2_k127_3265725_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 602.0
PYH2_k127_3265725_1 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 533.0
PYH2_k127_3265725_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 461.0
PYH2_k127_3265725_3 GYD domain - - - 0.000000000000000000000000000000000005529 139.0
PYH2_k127_3265725_4 UTRA domain K03710 - - 0.0000000000000000005381 87.0
PYH2_k127_326754_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1109.0
PYH2_k127_326754_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.258e-250 776.0
PYH2_k127_326754_2 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
PYH2_k127_326754_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000004275 229.0
PYH2_k127_326754_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00006381 46.0
PYH2_k127_3278501_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1145.0
PYH2_k127_3278501_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 292.0
PYH2_k127_3278501_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000002331 226.0
PYH2_k127_3278501_3 PIN domain - - - 0.00000000000000000000000000025 119.0
PYH2_k127_3278501_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000002025 90.0
PYH2_k127_3299948_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.529e-297 920.0
PYH2_k127_3299948_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 7.341e-259 802.0
PYH2_k127_3299948_10 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 375.0
PYH2_k127_3299948_11 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 273.0
PYH2_k127_3299948_12 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003972 248.0
PYH2_k127_3299948_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000002838 240.0
PYH2_k127_3299948_14 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001017 228.0
PYH2_k127_3299948_15 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000001572 228.0
PYH2_k127_3299948_16 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000001571 203.0
PYH2_k127_3299948_17 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000009283 172.0
PYH2_k127_3299948_18 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000000004138 153.0
PYH2_k127_3299948_19 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000000000000000001564 152.0
PYH2_k127_3299948_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 3.837e-218 689.0
PYH2_k127_3299948_20 PFAM Sporulation domain protein - - - 0.0000000000000000000000000002161 117.0
PYH2_k127_3299948_21 Protein of unknown function (DUF2892) - - - 0.00000000000000000000008225 102.0
PYH2_k127_3299948_22 Major Facilitator Superfamily - - - 0.00000000002571 67.0
PYH2_k127_3299948_23 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000644 61.0
PYH2_k127_3299948_3 MacB-like periplasmic core domain K02004 - - 3.155e-197 621.0
PYH2_k127_3299948_4 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 609.0
PYH2_k127_3299948_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 582.0
PYH2_k127_3299948_6 Multidrug ABC transporter permease K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 581.0
PYH2_k127_3299948_7 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 539.0
PYH2_k127_3299948_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 477.0
PYH2_k127_3299948_9 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 416.0
PYH2_k127_3339782_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 518.0
PYH2_k127_3339782_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 321.0
PYH2_k127_3339782_2 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001489 262.0
PYH2_k127_3339782_3 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000009085 246.0
PYH2_k127_3353869_0 Large family of predicted nucleotide-binding domains K07175 - - 1.078e-283 878.0
PYH2_k127_3353869_1 PFAM Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 1.561e-239 744.0
PYH2_k127_3353869_2 homoserine dehydrogenase K00003 - 1.1.1.3 3.472e-225 719.0
PYH2_k127_3353869_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 287.0
PYH2_k127_3353869_4 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000002597 219.0
PYH2_k127_3353869_5 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000001107 168.0
PYH2_k127_3365650_0 Histidine kinase K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000184 283.0
PYH2_k127_3365650_1 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000021 178.0
PYH2_k127_3365650_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000001025 152.0
PYH2_k127_3387404_0 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1114.0
PYH2_k127_3387404_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000001122 244.0
PYH2_k127_3387404_2 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000002908 241.0
PYH2_k127_3387404_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000000007745 199.0
PYH2_k127_3387404_4 2TM domain - - - 0.00000000000000000002015 94.0
PYH2_k127_3387404_5 - - - - 0.00000000000000003665 89.0
PYH2_k127_3424971_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 5.647e-236 746.0
PYH2_k127_3424971_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 493.0
PYH2_k127_3424971_10 Methyltransferase domain - - - 0.000001079 55.0
PYH2_k127_3424971_11 SMART extracellular solute-binding protein, family 3 K02030 - - 0.00004337 46.0
PYH2_k127_3424971_2 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 417.0
PYH2_k127_3424971_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 385.0
PYH2_k127_3424971_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 367.0
PYH2_k127_3424971_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 330.0
PYH2_k127_3424971_6 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000000000000000001223 177.0
PYH2_k127_3424971_7 - - - - 0.0000000000000000000000000000000001593 150.0
PYH2_k127_3424971_8 Beta-lactamase superfamily domain - - - 0.0000000000000000000000004405 116.0
PYH2_k127_3424971_9 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000003154 72.0
PYH2_k127_342609_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 463.0
PYH2_k127_342609_1 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 375.0
PYH2_k127_342609_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 325.0
PYH2_k127_342609_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 277.0
PYH2_k127_342609_4 pilus assembly K02676 - - 0.0000000000000000000000000000000000000000000000000000000000001322 214.0
PYH2_k127_342609_5 PFAM Ankyrin K06867 - - 0.00000000000000000000000000000000000000000000000000000001093 207.0
PYH2_k127_342609_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000001857 192.0
PYH2_k127_342609_7 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000002577 150.0
PYH2_k127_342609_8 - - - - 0.00000000000003479 76.0
PYH2_k127_342609_9 - - - - 0.0000000000006113 76.0
PYH2_k127_3447471_0 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 518.0
PYH2_k127_3447471_1 Belongs to the bacterial flagellin family K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004349 258.0
PYH2_k127_3479137_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 4.853e-224 700.0
PYH2_k127_3479137_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000006163 78.0
PYH2_k127_3479137_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000003253 59.0
PYH2_k127_3505395_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 451.0
PYH2_k127_3505395_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 331.0
PYH2_k127_3505395_2 KR domain K10780 - 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 310.0
PYH2_k127_3505395_3 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000001695 248.0
PYH2_k127_3505395_4 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000002628 237.0
PYH2_k127_3505395_5 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000002895 151.0
PYH2_k127_3505395_6 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000009232 101.0
PYH2_k127_3505395_7 FabA-like domain - - - 0.000000000000000000001217 105.0
PYH2_k127_350632_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1658.0
PYH2_k127_350632_1 COG1653 ABC-type sugar transport system, periplasmic component K17321 - - 2.8e-321 992.0
PYH2_k127_350632_2 ABC transporter K17324 - - 0.0000000000000000004237 91.0
PYH2_k127_3513533_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.913e-236 739.0
PYH2_k127_3513533_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 565.0
PYH2_k127_3513533_2 Belongs to the arginase family K12255 - 3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 565.0
PYH2_k127_3513533_3 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000113 259.0
PYH2_k127_3533333_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 578.0
PYH2_k127_3533333_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 449.0
PYH2_k127_3533333_2 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 375.0
PYH2_k127_3540184_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 308.0
PYH2_k127_3540184_1 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 301.0
PYH2_k127_3540184_2 Tfp pilus assembly protein FimV - - - 0.0000000000000000007368 92.0
PYH2_k127_3540184_3 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000009466 68.0
PYH2_k127_3582950_0 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 433.0
PYH2_k127_3582950_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 319.0
PYH2_k127_3582950_2 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 324.0
PYH2_k127_3582950_3 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002159 295.0
PYH2_k127_3582950_4 LysR substrate binding domain - - - 0.00000000000000000002746 96.0
PYH2_k127_3582950_5 Protein of unknown function (DUF3025) - - - 0.000000000009878 69.0
PYH2_k127_3582950_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000009054 53.0
PYH2_k127_3600704_0 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 344.0
PYH2_k127_3600704_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000002174 230.0
PYH2_k127_3600704_2 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000007106 208.0
PYH2_k127_3600704_3 - - - - 0.0000000000000000000000000000000000004355 141.0
PYH2_k127_3600704_4 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000004927 112.0
PYH2_k127_3621831_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 6.61e-299 932.0
PYH2_k127_3621831_1 Cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 592.0
PYH2_k127_3621831_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 554.0
PYH2_k127_3621831_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 551.0
PYH2_k127_3621831_4 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 436.0
PYH2_k127_3621831_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
PYH2_k127_3621831_6 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 343.0
PYH2_k127_3621831_7 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007268 274.0
PYH2_k127_3621831_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000004803 110.0
PYH2_k127_3662670_0 Transport of potassium into the cell K03549 - - 1.333e-319 987.0
PYH2_k127_3662670_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 3.588e-261 808.0
PYH2_k127_3662670_10 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000001243 190.0
PYH2_k127_3662670_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000006587 184.0
PYH2_k127_3662670_12 HMGL-like K01640 - 4.1.3.4 0.000000000000000000009017 106.0
PYH2_k127_3662670_13 PFAM regulatory protein LysR K11921 - - 0.0000000000179 68.0
PYH2_k127_3662670_14 Tripartite tricarboxylate transporter family receptor - - - 0.000000000983 62.0
PYH2_k127_3662670_15 protein involved in benzoate metabolism K05782 - - 0.00003999 49.0
PYH2_k127_3662670_2 Ammonium Transporter K03320 - - 9.62e-243 760.0
PYH2_k127_3662670_3 PFAM ABC transporter related K15738 - - 5.571e-224 706.0
PYH2_k127_3662670_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 4.73e-199 628.0
PYH2_k127_3662670_5 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 498.0
PYH2_k127_3662670_6 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 350.0
PYH2_k127_3662670_7 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000003776 213.0
PYH2_k127_3662670_8 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000000003862 211.0
PYH2_k127_3662670_9 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000001072 221.0
PYH2_k127_3673309_0 curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000001031 228.0
PYH2_k127_3673309_1 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000002113 83.0
PYH2_k127_3688350_0 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 507.0
PYH2_k127_3688350_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 448.0
PYH2_k127_3688350_2 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 335.0
PYH2_k127_3688350_3 COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes K11159,K21822 - 1.13.11.82 0.00000000000000000000000000000000000000000000000001296 183.0
PYH2_k127_3688350_4 DsrC like protein - - - 0.0000000000000000000000000000000001969 135.0
PYH2_k127_3708881_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1740.0
PYH2_k127_3708881_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 7.12e-216 687.0
PYH2_k127_3708881_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 360.0
PYH2_k127_3727254_0 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 387.0
PYH2_k127_3727254_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000008118 204.0
PYH2_k127_3727254_2 - - - - 0.0000000000000000000000000006425 118.0
PYH2_k127_3777437_0 Sulfate permease and related transporters (MFS superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 442.0
PYH2_k127_3777437_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 403.0
PYH2_k127_3777437_10 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000001707 111.0
PYH2_k127_3777437_11 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000006107 94.0
PYH2_k127_3777437_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 356.0
PYH2_k127_3777437_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17722 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 283.0
PYH2_k127_3777437_4 Transcriptional regulator K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001968 275.0
PYH2_k127_3777437_5 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000002895 222.0
PYH2_k127_3777437_6 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000002875 190.0
PYH2_k127_3777437_7 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000002138 181.0
PYH2_k127_3777437_9 Haem-degrading - - - 0.00000000000000000000000000000000005429 139.0
PYH2_k127_3777998_0 PQQ-like domain - - - 1.098e-234 738.0
PYH2_k127_3777998_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 322.0
PYH2_k127_3777998_2 PBP superfamily domain K07219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009784 278.0
PYH2_k127_3777998_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009934 261.0
PYH2_k127_3777998_4 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000001373 246.0
PYH2_k127_3777998_5 - - - - 0.00000000000000000000000000000000000000000000000000000000006495 208.0
PYH2_k127_3777998_6 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000995 194.0
PYH2_k127_3794807_0 Peptidase C39 family K13409 - - 2.324e-312 971.0
PYH2_k127_3794807_1 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001134 298.0
PYH2_k127_3794807_10 Universal stress protein family - - - 0.00000000000000000000000000000000000003266 149.0
PYH2_k127_3794807_11 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000001453 147.0
PYH2_k127_3794807_12 IMP dehydrogenase activity - - - 0.000000000000000001199 93.0
PYH2_k127_3794807_13 Phasin protein - - - 0.000000000001765 74.0
PYH2_k127_3794807_14 - - - - 0.00000004968 62.0
PYH2_k127_3794807_2 bacterial OsmY and nodulation domain K04065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002615 267.0
PYH2_k127_3794807_3 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001422 246.0
PYH2_k127_3794807_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
PYH2_k127_3794807_5 HlyD family secretion protein K13408 - - 0.0000000000000000000000000000000000000000000000000000000000000154 220.0
PYH2_k127_3794807_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000005362 222.0
PYH2_k127_3794807_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000006358 209.0
PYH2_k127_3794807_8 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000287 203.0
PYH2_k127_3794807_9 SpoIIAA-like - - - 0.000000000000000000000000000000000000000000001138 175.0
PYH2_k127_3797036_0 Putative diguanylate phosphodiesterase - - - 1.548e-244 775.0
PYH2_k127_3797036_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.672e-210 663.0
PYH2_k127_3797036_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 469.0
PYH2_k127_3797036_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 336.0
PYH2_k127_3797036_4 short-chain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 301.0
PYH2_k127_3797036_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009789 283.0
PYH2_k127_3797036_6 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000000005729 219.0
PYH2_k127_3797036_7 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000000000001875 171.0
PYH2_k127_3798011_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 526.0
PYH2_k127_3798011_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008834 264.0
PYH2_k127_3798011_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000008131 229.0
PYH2_k127_379986_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 458.0
PYH2_k127_379986_1 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002322 273.0
PYH2_k127_379986_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000812 214.0
PYH2_k127_3801161_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 410.0
PYH2_k127_3817091_0 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000002629 88.0
PYH2_k127_3818981_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.375e-271 842.0
PYH2_k127_3818981_1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - 2.537e-222 694.0
PYH2_k127_3818981_10 - - - - 0.00005972 45.0
PYH2_k127_3818981_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.841e-214 674.0
PYH2_k127_3818981_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 1.266e-206 650.0
PYH2_k127_3818981_4 Autoinducer binding domain K07782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009669 270.0
PYH2_k127_3818981_5 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000001274 173.0
PYH2_k127_3818981_6 Sporulation related domain K03749 - - 0.0000000000000000000000009633 104.0
PYH2_k127_3818981_7 PFAM Integrase catalytic region K07494 - - 0.0000000000000000004629 86.0
PYH2_k127_3818981_9 - - - - 0.0000001568 54.0
PYH2_k127_3827397_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.258e-234 733.0
PYH2_k127_3827397_1 Tripartite ATP-independent periplasmic transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 319.0
PYH2_k127_3829598_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0 1176.0
PYH2_k127_3829598_1 Periplasmic binding protein K01999 - - 2.84e-203 641.0
PYH2_k127_3829598_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 430.0
PYH2_k127_3829598_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 372.0
PYH2_k127_3829598_4 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.0000000001722 64.0
PYH2_k127_3840833_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 463.0
PYH2_k127_3840833_1 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004572 280.0
PYH2_k127_3840833_2 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001666 245.0
PYH2_k127_3840833_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000003277 199.0
PYH2_k127_3840833_4 PFAM Tol-Pal system TolA K03646 - - 0.00000000000000000000000000000000000002152 145.0
PYH2_k127_3841708_0 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 3.607e-197 621.0
PYH2_k127_3841708_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 543.0
PYH2_k127_3841708_2 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006883 238.0
PYH2_k127_3867161_0 Phage plasmid primase P4 family K06919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 324.0
PYH2_k127_3867161_2 - - - - 0.000000000000000000000000000000004246 131.0
PYH2_k127_3867161_3 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000002378 108.0
PYH2_k127_3867161_4 - - - - 0.0000000000000000000000003239 107.0
PYH2_k127_3867161_5 - - - - 0.00000000000000007162 94.0
PYH2_k127_3869646_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1075.0
PYH2_k127_3869646_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 4.971e-198 621.0
PYH2_k127_3869646_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 297.0
PYH2_k127_3869646_3 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006744 239.0
PYH2_k127_3869646_4 Protein of unknown function (DUF3306) - - - 0.0000000000000000000000000000000000000004012 161.0
PYH2_k127_3870487_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1365.0
PYH2_k127_3870487_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 9.301e-255 791.0
PYH2_k127_3870487_10 Protein of unknown function (DUF721) - - - 0.000000000000000009174 87.0
PYH2_k127_3870487_11 recombinase activity - - - 0.0006373 44.0
PYH2_k127_3870487_2 Protein of unknown function (DUF1631) - - - 2.675e-221 712.0
PYH2_k127_3870487_3 peptidase K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 437.0
PYH2_k127_3870487_4 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 410.0
PYH2_k127_3870487_5 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 412.0
PYH2_k127_3870487_6 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 344.0
PYH2_k127_3870487_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 320.0
PYH2_k127_3870487_8 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000000000000000008862 235.0
PYH2_k127_3870487_9 Starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000000000000523 214.0
PYH2_k127_3874294_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 400.0
PYH2_k127_3874294_1 - - - - 0.0000000000000000000000000000000000000000000000000006024 202.0
PYH2_k127_3874294_2 LysR substrate binding domain - - - 0.00000000000000000000001213 103.0
PYH2_k127_3874294_3 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000001436 82.0
PYH2_k127_3874294_5 GtrA-like protein - - - 0.0002221 53.0
PYH2_k127_3874778_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1168.0
PYH2_k127_3874778_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 289.0
PYH2_k127_3874778_2 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000000000000000006097 226.0
PYH2_k127_3874778_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000003193 53.0
PYH2_k127_3876368_0 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 399.0
PYH2_k127_3876368_1 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 291.0
PYH2_k127_3876368_2 Domain of unknown function (DUF4387) - - - 0.000000000000000000000000000581 123.0
PYH2_k127_3876368_3 PFAM conserved - - - 0.0000000000000223 82.0
PYH2_k127_3876368_4 - - - - 0.00000000002478 74.0
PYH2_k127_3880170_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 453.0
PYH2_k127_3880170_1 PFAM class II aldolase adducin family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 329.0
PYH2_k127_3880170_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000463 200.0
PYH2_k127_3887084_0 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 5.64e-210 666.0
PYH2_k127_3887084_1 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 534.0
PYH2_k127_3887084_2 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 327.0
PYH2_k127_3887084_3 Acetyltransferase (GNAT) domain K02348 - - 0.000000000000000000000000000000000000000000000000000001914 209.0
PYH2_k127_3887084_4 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000001338 181.0
PYH2_k127_3887895_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 494.0
PYH2_k127_3887895_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 393.0
PYH2_k127_3887895_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 307.0
PYH2_k127_3887895_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000003736 240.0
PYH2_k127_3901395_0 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 558.0
PYH2_k127_3901395_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 528.0
PYH2_k127_3901395_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 389.0
PYH2_k127_3901395_3 (ABC) transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 417.0
PYH2_k127_3901395_4 PFAM iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.0000000000000000000000000000000000000000001054 163.0
PYH2_k127_3905312_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0 1197.0
PYH2_k127_3905312_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0 1047.0
PYH2_k127_3905312_10 FCD - - - 0.000000000000000000000000000001695 122.0
PYH2_k127_3905312_2 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 2.477e-284 889.0
PYH2_k127_3905312_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 2.109e-215 682.0
PYH2_k127_3905312_4 Belongs to the thiolase family - - - 7.426e-215 683.0
PYH2_k127_3905312_5 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 610.0
PYH2_k127_3905312_6 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000000001985 219.0
PYH2_k127_3905312_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000003395 224.0
PYH2_k127_3905312_8 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000004301 167.0
PYH2_k127_3905312_9 MaoC like domain - - - 0.0000000000000000000000000000000000000000001632 163.0
PYH2_k127_3912264_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.827e-218 691.0
PYH2_k127_3912264_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 527.0
PYH2_k127_3912264_2 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 312.0
PYH2_k127_3912264_3 2-Keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000002231 235.0
PYH2_k127_3912264_4 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000019 200.0
PYH2_k127_3912264_5 Smr domain - - - 0.000000000000000000000000000001703 134.0
PYH2_k127_3917506_0 Amidase K01426 - 3.5.1.4 1.27e-242 759.0
PYH2_k127_3917506_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000374 208.0
PYH2_k127_3931859_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.123e-292 900.0
PYH2_k127_3931859_1 TIGRFAM nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 1.175e-250 779.0
PYH2_k127_3931859_10 Creatinine amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 335.0
PYH2_k127_3931859_11 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 298.0
PYH2_k127_3931859_12 HAD-hyrolase-like K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006287 291.0
PYH2_k127_3931859_13 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000001628 213.0
PYH2_k127_3931859_14 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000009589 200.0
PYH2_k127_3931859_15 - - - - 0.0000000000000000000000000000000000000000000005939 171.0
PYH2_k127_3931859_2 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 5.818e-198 625.0
PYH2_k127_3931859_3 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 517.0
PYH2_k127_3931859_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 502.0
PYH2_k127_3931859_5 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 481.0
PYH2_k127_3931859_6 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 440.0
PYH2_k127_3931859_7 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 426.0
PYH2_k127_3931859_8 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 379.0
PYH2_k127_3931859_9 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 334.0
PYH2_k127_3932737_0 TIGRFAM type I secretion system ATPase K12541 - - 6e-323 1005.0
PYH2_k127_3932737_1 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 1.572e-198 634.0
PYH2_k127_3932737_2 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 359.0
PYH2_k127_3932737_3 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 288.0
PYH2_k127_3932737_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000002316 115.0
PYH2_k127_3932737_5 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.0000000000001194 75.0
PYH2_k127_3934095_0 AMP-binding enzyme K12508 - 6.2.1.34 1.275e-289 899.0
PYH2_k127_3934095_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 2.379e-195 629.0
PYH2_k127_3934095_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 514.0
PYH2_k127_3934095_3 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 529.0
PYH2_k127_3934095_4 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
PYH2_k127_3934095_5 - - - - 0.00000000000000000000003887 100.0
PYH2_k127_3936598_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1059.0
PYH2_k127_3936598_1 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 502.0
PYH2_k127_3936598_2 Belongs to the peptidase S8 family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 340.0
PYH2_k127_3936598_3 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 296.0
PYH2_k127_3936598_4 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001113 230.0
PYH2_k127_3936598_5 Phasin protein - - - 0.0000000000000000000000000000000000003087 148.0
PYH2_k127_3936598_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.00000000000000000000000000000000001248 139.0
PYH2_k127_3936598_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.0000000000000006609 87.0
PYH2_k127_3936598_8 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.000002163 59.0
PYH2_k127_3937895_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 1.956e-223 698.0
PYH2_k127_3937895_1 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 421.0
PYH2_k127_3937895_2 Sensors of blue-light using FAD - - - 0.00000000000000000000000000000000000000000000000000000000475 214.0
PYH2_k127_3937895_3 - - - - 0.00000000000000000000000000000000000000000001765 172.0
PYH2_k127_3937895_4 cytochrome - - - 0.0000000000000000000000003519 108.0
PYH2_k127_3937895_5 LemA family K03744 - - 0.00000000005845 66.0
PYH2_k127_3937895_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000008585 54.0
PYH2_k127_3956791_0 PFAM AMP-dependent synthetase and ligase K01911 - 6.2.1.26 5.914e-201 635.0
PYH2_k127_3956791_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 544.0
PYH2_k127_3956791_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 314.0
PYH2_k127_3956791_3 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000003245 230.0
PYH2_k127_3968290_0 MMPL family K03296,K18138,K18902 - - 0.0 1296.0
PYH2_k127_3968290_1 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 552.0
PYH2_k127_3968290_2 PFAM beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 459.0
PYH2_k127_3968290_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 383.0
PYH2_k127_3968290_4 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000007004 220.0
PYH2_k127_3968290_5 Outer membrane efflux protein - - - 0.00001816 57.0
PYH2_k127_3978135_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1522.0
PYH2_k127_3978135_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 451.0
PYH2_k127_3978135_2 17 kDa surface antigen - - - 0.00000000000000000000000000000000005743 141.0
PYH2_k127_3978135_3 Protein of unknown function (DUF1501) - - - 0.000000000004267 73.0
PYH2_k127_4001386_0 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 1.08e-295 917.0
PYH2_k127_4001386_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 271.0
PYH2_k127_4001386_2 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002229 245.0
PYH2_k127_4001386_3 Auxin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000006331 223.0
PYH2_k127_4001386_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000004984 216.0
PYH2_k127_4001386_6 - - - - 0.00000000000000000000001267 115.0
PYH2_k127_4003404_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1461.0
PYH2_k127_4003404_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.669e-298 922.0
PYH2_k127_4003404_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 380.0
PYH2_k127_4003404_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 335.0
PYH2_k127_4003404_4 Molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000179 245.0
PYH2_k127_4003404_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000000000000001393 170.0
PYH2_k127_4003404_6 - - - - 0.000000000000000000000000000000000000001189 154.0
PYH2_k127_4003404_7 Uncharacterized ACR, COG1993 - - - 0.000000000000000000000000000000000001526 143.0
PYH2_k127_4016639_0 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 430.0
PYH2_k127_4016639_1 plasmid maintenance system antidote protein K21498 - - 0.0000000000000000000000000000000000000001005 154.0
PYH2_k127_4016639_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000001056 140.0
PYH2_k127_4030965_0 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 595.0
PYH2_k127_4030965_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 580.0
PYH2_k127_4030965_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 527.0
PYH2_k127_4030965_3 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 414.0
PYH2_k127_4030965_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 376.0
PYH2_k127_4030965_5 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 330.0
PYH2_k127_4030965_6 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 297.0
PYH2_k127_4030965_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000006783 239.0
PYH2_k127_4030965_8 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000005792 172.0
PYH2_k127_4030965_9 Rhomboid family - - - 0.000000000000000000000000000000000000000002809 162.0
PYH2_k127_4041252_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.106e-215 676.0
PYH2_k127_4041252_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 398.0
PYH2_k127_4041252_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001282 289.0
PYH2_k127_4041252_3 (Lipo)protein - - - 0.00000000000000000000000000000000000000000000000003962 183.0
PYH2_k127_4041252_4 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000003986 179.0
PYH2_k127_4041252_5 histidine kinase A domain protein - - - 0.000000000000000000000000000000000001255 141.0
PYH2_k127_4041252_6 Protein of unknown function (DUF3460) - - - 0.0000000000000000000000000234 110.0
PYH2_k127_4041252_7 - - - - 0.0000000000000004555 89.0
PYH2_k127_4048114_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1716.0
PYH2_k127_4048114_1 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 590.0
PYH2_k127_4048114_10 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000002852 169.0
PYH2_k127_4048114_11 DinB superfamily - - - 0.0000000000000000000000000000000000000000000004188 180.0
PYH2_k127_4048114_12 - - - - 0.00000000000000000000000000000000000000005346 155.0
PYH2_k127_4048114_13 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000000000000000000000003516 158.0
PYH2_k127_4048114_14 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000000004001 143.0
PYH2_k127_4048114_15 PFAM Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000371 129.0
PYH2_k127_4048114_16 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000004293 99.0
PYH2_k127_4048114_17 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000005062 70.0
PYH2_k127_4048114_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 546.0
PYH2_k127_4048114_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 517.0
PYH2_k127_4048114_4 Phosphomethylpyrimidine kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 475.0
PYH2_k127_4048114_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 428.0
PYH2_k127_4048114_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 392.0
PYH2_k127_4048114_7 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 370.0
PYH2_k127_4048114_8 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 308.0
PYH2_k127_4048114_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000008419 228.0
PYH2_k127_4051823_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1407.0
PYH2_k127_4063980_0 belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001025 235.0
PYH2_k127_4063980_1 - - - - 0.00000000000245 78.0
PYH2_k127_408780_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1147.0
PYH2_k127_408780_1 D-amino acid K00285 - 1.4.5.1 1.463e-216 678.0
PYH2_k127_408780_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002387 246.0
PYH2_k127_408780_11 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000000000000000000000001317 188.0
PYH2_k127_408780_12 - - - - 0.000000000000000000000000000000000000000005902 162.0
PYH2_k127_408780_13 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000006064 128.0
PYH2_k127_408780_2 Major Facilitator Superfamily - - - 4.034e-204 640.0
PYH2_k127_408780_3 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 581.0
PYH2_k127_408780_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 489.0
PYH2_k127_408780_5 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 411.0
PYH2_k127_408780_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 357.0
PYH2_k127_408780_7 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 346.0
PYH2_k127_408780_8 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 328.0
PYH2_k127_408780_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007138 268.0
PYH2_k127_4092523_0 TIGRFAM acyltransferase, WS DGAT MGAT - - - 1.686e-214 680.0
PYH2_k127_4092523_1 Protein of unknown function (DUF1298) - - - 3.581e-200 634.0
PYH2_k127_4092523_2 COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes K11159,K21822 - 1.13.11.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 517.0
PYH2_k127_4092523_3 PGAP1-like protein - - - 0.00000000000000000000000704 111.0
PYH2_k127_4092523_4 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.000000156 60.0
PYH2_k127_4102941_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 591.0
PYH2_k127_4102941_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 555.0
PYH2_k127_4102941_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 523.0
PYH2_k127_4102941_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 459.0
PYH2_k127_4102941_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 384.0
PYH2_k127_4102941_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
PYH2_k127_4102941_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009812 264.0
PYH2_k127_4102941_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000009684 202.0
PYH2_k127_4102941_8 Domain of unknown function (DUF4845) - - - 0.0000000000000000000000000000000000000001224 155.0
PYH2_k127_4102941_9 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000006644 119.0
PYH2_k127_4113956_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.356e-233 738.0
PYH2_k127_4113956_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 574.0
PYH2_k127_4113956_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 515.0
PYH2_k127_4113956_3 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 323.0
PYH2_k127_4113956_4 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 308.0
PYH2_k127_4113956_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
PYH2_k127_4113956_6 Histidine kinase K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000002573 132.0
PYH2_k127_4113956_7 Auxin Efflux Carrier K07088 - - 0.00000000000000001593 83.0
PYH2_k127_4123444_0 Transposase DDE domain - - - 2.942e-272 846.0
PYH2_k127_4123444_1 Tripartite tricarboxylate transporter TctA family - - - 9.714e-269 832.0
PYH2_k127_4123444_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 553.0
PYH2_k127_4123444_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 543.0
PYH2_k127_4123444_4 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 517.0
PYH2_k127_4123444_5 6-phosphogluconate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 450.0
PYH2_k127_4123444_6 - - - - 0.00000000000000000000000000000000000000000000001185 190.0
PYH2_k127_4123444_7 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000002068 152.0
PYH2_k127_4123444_8 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000003702 143.0
PYH2_k127_4123444_9 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000001055 116.0
PYH2_k127_4126087_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.188e-314 971.0
PYH2_k127_4187585_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 3.841e-311 964.0
PYH2_k127_427332_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0 1312.0
PYH2_k127_427332_1 B12 binding domain - - - 3.267e-210 670.0
PYH2_k127_427332_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 420.0
PYH2_k127_427332_3 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 380.0
PYH2_k127_427332_4 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate K03340 - 1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
PYH2_k127_427332_5 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000003898 192.0
PYH2_k127_427332_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000001985 110.0
PYH2_k127_427332_7 Protein of unknown function (DUF504) - - - 0.00000000000000000000002229 103.0
PYH2_k127_4300529_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2086.0
PYH2_k127_4300529_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1233.0
PYH2_k127_4300529_10 Predicted integral membrane protein (DUF2189) - - - 0.00004446 54.0
PYH2_k127_4300529_11 - - - - 0.000249 53.0
PYH2_k127_4300529_2 Collagenase K08303 - - 2.249e-294 915.0
PYH2_k127_4300529_3 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 482.0
PYH2_k127_4300529_4 Luciferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 484.0
PYH2_k127_4300529_5 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 407.0
PYH2_k127_4300529_6 Predicted metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 368.0
PYH2_k127_4300529_7 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 330.0
PYH2_k127_4300529_8 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006235 265.0
PYH2_k127_4300529_9 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002099 210.0
PYH2_k127_4307561_0 FtsX-like permease family K02004 - - 7.121e-285 887.0
PYH2_k127_4336297_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.632e-228 715.0
PYH2_k127_4336297_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004904 248.0
PYH2_k127_4336297_2 Type II transport protein GspH K08084 - - 0.000000000000000000000000000000000000000000000000002443 188.0
PYH2_k127_4336297_3 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000009749 98.0
PYH2_k127_4356153_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 566.0
PYH2_k127_4356153_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 423.0
PYH2_k127_4356153_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 404.0
PYH2_k127_4364580_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 8.227e-252 789.0
PYH2_k127_4364580_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001298 273.0
PYH2_k127_4364580_2 Universal stress protein family - - - 0.000000000000000000000000000000000000000001872 162.0
PYH2_k127_4364580_3 Universal stress protein family - - - 0.00000000000000000000002447 115.0
PYH2_k127_4367409_0 Putative diguanylate phosphodiesterase - - - 0.0 1056.0
PYH2_k127_4367409_1 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000203 165.0
PYH2_k127_4367409_2 histidine kinase A domain protein - - - 0.0000000000002536 78.0
PYH2_k127_4367409_3 Diguanylate cyclase K13590 - 2.7.7.65 0.0000000000004547 74.0
PYH2_k127_4405922_0 DEAD DEAH box helicase K03724 - - 0.0 1048.0
PYH2_k127_4405922_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 5.108e-279 870.0
PYH2_k127_4405922_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000007131 203.0
PYH2_k127_4405922_11 FIST_C - - - 0.00000000000001031 73.0
PYH2_k127_4405922_12 - - - - 0.0002145 49.0
PYH2_k127_4405922_2 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.701e-270 843.0
PYH2_k127_4405922_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.164e-253 789.0
PYH2_k127_4405922_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 3.158e-213 670.0
PYH2_k127_4405922_5 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 490.0
PYH2_k127_4405922_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 471.0
PYH2_k127_4405922_7 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 374.0
PYH2_k127_4405922_8 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 368.0
PYH2_k127_4405922_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 298.0
PYH2_k127_4407743_0 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 515.0
PYH2_k127_4407743_1 SapC - - - 0.000000000000000000000000000000000000000000001024 170.0
PYH2_k127_4407743_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000008999 92.0
PYH2_k127_445381_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 597.0
PYH2_k127_445381_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 426.0
PYH2_k127_445381_2 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007012 297.0
PYH2_k127_445381_3 ABC transporter - - - 0.00000000000000000000000000000000000000000000000003128 186.0
PYH2_k127_445381_4 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000001247 129.0
PYH2_k127_445381_5 ABC-2 family transporter protein - - - 0.00001427 56.0
PYH2_k127_4462667_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 381.0
PYH2_k127_4462667_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 315.0
PYH2_k127_4462667_2 SMART AAA ATPase K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001 261.0
PYH2_k127_4507373_0 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 385.0
PYH2_k127_4507373_1 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 293.0
PYH2_k127_4507373_2 Amidohydrolase family K05603 - 3.5.3.13 0.0007327 51.0
PYH2_k127_4512962_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 485.0
PYH2_k127_4512962_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 396.0
PYH2_k127_4512962_2 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 365.0
PYH2_k127_4512962_3 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000004171 188.0
PYH2_k127_4512962_4 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.00000000000000000000000000000002858 131.0
PYH2_k127_4512962_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA - - - 0.000000000000000000000000006363 112.0
PYH2_k127_4512962_6 LytTr DNA-binding domain - - - 0.000000000000000000001808 94.0
PYH2_k127_452520_0 Na+/Pi-cotransporter K03324 - - 9.087e-236 740.0
PYH2_k127_452520_1 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 1.143e-204 643.0
PYH2_k127_452520_2 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 6.159e-198 620.0
PYH2_k127_452520_3 Alanine dehydrogenase/PNT, C-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 573.0
PYH2_k127_452520_4 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 484.0
PYH2_k127_452520_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 401.0
PYH2_k127_452520_6 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000001291 222.0
PYH2_k127_452520_7 Phosphonate utilization associated transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000001569 216.0
PYH2_k127_4535251_0 Proton-conducting membrane transporter - - - 1.8e-257 800.0
PYH2_k127_4536687_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1239.0
PYH2_k127_4536687_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 8.945e-267 842.0
PYH2_k127_4536687_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.01e-257 810.0
PYH2_k127_4536687_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 604.0
PYH2_k127_4536687_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 537.0
PYH2_k127_4536687_5 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 378.0
PYH2_k127_4536687_6 Roadblock/LC7 domain K07131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 347.0
PYH2_k127_4536687_7 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000000000000001022 237.0
PYH2_k127_4536687_8 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00004901 49.0
PYH2_k127_4646709_0 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 2.351e-250 775.0
PYH2_k127_4646709_1 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 383.0
PYH2_k127_4646709_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000003442 98.0
PYH2_k127_4646709_3 ABC transporter substrate binding protein - - - 0.0000000000000000001033 95.0
PYH2_k127_4646709_4 ABC transporter substrate binding protein K01989 - - 0.00001306 51.0
PYH2_k127_4646721_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1097.0
PYH2_k127_4646721_1 general secretion pathway protein K02453 - - 6.467e-275 863.0
PYH2_k127_4646721_10 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 333.0
PYH2_k127_4646721_11 Type II secretion system (T2SS), protein N K02463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000573 296.0
PYH2_k127_4646721_12 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000000000000000000000000000000000000000000000000000001117 241.0
PYH2_k127_4646721_13 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000003062 232.0
PYH2_k127_4646721_14 general secretion pathway protein K02458 - - 0.0000000000000000000000000000000000000000000000001288 182.0
PYH2_k127_4646721_15 General secretion pathway protein H K02457 - - 0.0000000000000000000000000000000000000001269 157.0
PYH2_k127_4646721_16 PFAM General secretion pathway, M protein K02462 - - 0.000000000000000000000000000000000000127 150.0
PYH2_k127_4646721_17 general secretion pathway protein K02452 - - 0.00000000000000000000000000002986 125.0
PYH2_k127_4646721_2 TIGRFAM general secretory pathway protein E K02454,K02652 - - 3.671e-247 773.0
PYH2_k127_4646721_3 Putative nucleotidyltransferase substrate binding domain K07182 - - 1.092e-196 631.0
PYH2_k127_4646721_4 general secretion pathway protein K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 562.0
PYH2_k127_4646721_5 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 542.0
PYH2_k127_4646721_6 PFAM 5-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 492.0
PYH2_k127_4646721_7 General secretion pathway K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 401.0
PYH2_k127_4646721_8 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 392.0
PYH2_k127_4646721_9 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 366.0
PYH2_k127_4650889_0 Carbamoyl-phosphate synthase L chain, ATP-binding - - - 1.314e-235 737.0
PYH2_k127_4650889_1 PFAM Diacylglycerol kinase, catalytic - - - 0.000000000000000000000000002299 118.0
PYH2_k127_4650889_2 xylulokinase activity K00854 - 2.7.1.17 0.00006446 47.0
PYH2_k127_4654541_0 Histidine kinase - - - 1.547e-229 723.0
PYH2_k127_4654541_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 341.0
PYH2_k127_4654541_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000001352 203.0
PYH2_k127_466884_0 lytic transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 589.0
PYH2_k127_466884_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 389.0
PYH2_k127_466884_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 295.0
PYH2_k127_466884_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000002519 252.0
PYH2_k127_466884_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000853 185.0
PYH2_k127_466884_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000006991 119.0
PYH2_k127_466884_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000549 65.0
PYH2_k127_4670228_0 PFAM NAD-dependent epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 517.0
PYH2_k127_4670228_1 Class II aldolase K01628,K22130 - 4.1.1.104,4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 314.0
PYH2_k127_4670228_2 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 0.0000000000000000000000001438 107.0
PYH2_k127_4676604_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1350.0
PYH2_k127_4676604_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.626e-222 704.0
PYH2_k127_4676604_10 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000004322 219.0
PYH2_k127_4676604_12 ABC transporter substrate binding protein K01989 - - 0.000000000000001014 83.0
PYH2_k127_4676604_13 transporter component K07112 - - 0.000003096 59.0
PYH2_k127_4676604_2 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 554.0
PYH2_k127_4676604_3 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 483.0
PYH2_k127_4676604_4 PFAM ABC transporter related K02017,K02045,K02049,K02052,K11076 - 3.6.3.25,3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 332.0
PYH2_k127_4676604_5 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 323.0
PYH2_k127_4676604_6 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001249 249.0
PYH2_k127_4676604_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001195 251.0
PYH2_k127_4676604_8 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005101 244.0
PYH2_k127_4676604_9 PFAM peptidase C15 pyroglutamyl peptidase I K01304 - 3.4.19.3 0.00000000000000000000000000000000000000000000000000000000000206 216.0
PYH2_k127_4682199_0 Peptidase M61 - - - 2.582e-223 707.0
PYH2_k127_4682199_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 442.0
PYH2_k127_4682199_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 460.0
PYH2_k127_4682199_3 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 389.0
PYH2_k127_4682199_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 335.0
PYH2_k127_4682199_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000003852 166.0
PYH2_k127_4705961_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 601.0
PYH2_k127_4705961_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 438.0
PYH2_k127_4705961_2 Belongs to the TPP enzyme family K04103 - 4.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002586 274.0
PYH2_k127_4705961_3 Universal stress protein - - - 0.0000000000000000000000000000000000000000000001956 173.0
PYH2_k127_4705961_4 zinc ion binding K06204 - - 0.0000000000000000000001718 102.0
PYH2_k127_4723308_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 331.0
PYH2_k127_4723308_1 phosphinothricin N-acetyltransferase activity K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000006541 233.0
PYH2_k127_4723308_2 Sodium Bile acid symporter family - - - 0.00000000000001588 81.0
PYH2_k127_4731570_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 391.0
PYH2_k127_4737210_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 484.0
PYH2_k127_4750976_0 GTP cyclohydrolase N terminal - - - 9.036e-246 761.0
PYH2_k127_4750976_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 7.137e-220 694.0
PYH2_k127_4750976_10 AAA domain - - - 0.00000000000000000000000000000000000000000000000002334 193.0
PYH2_k127_4750976_11 Protein of unknown function (DUF1688) - - - 0.00000000000000000000000000308 116.0
PYH2_k127_4750976_12 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000007875 79.0
PYH2_k127_4750976_14 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0001422 45.0
PYH2_k127_4750976_2 Zn_pept - - - 4.272e-206 645.0
PYH2_k127_4750976_3 ABC transporter K02056 - 3.6.3.17 5.654e-205 653.0
PYH2_k127_4750976_4 basic membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 542.0
PYH2_k127_4750976_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 521.0
PYH2_k127_4750976_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 496.0
PYH2_k127_4750976_7 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 421.0
PYH2_k127_4750976_8 haloacid dehalogenase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 316.0
PYH2_k127_4750976_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
PYH2_k127_4755273_0 Protein of unknown function (DUF3182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 341.0
PYH2_k127_4755273_1 Uncharacterised protein family (UPF0227) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004543 291.0
PYH2_k127_4755273_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001233 272.0
PYH2_k127_4755273_3 Domain of unknown function (DUF2383) - - - 0.000000000000000000000000000000000000002351 155.0
PYH2_k127_4755273_4 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000005995 109.0
PYH2_k127_4756461_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 561.0
PYH2_k127_4756461_1 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 383.0
PYH2_k127_4756461_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 369.0
PYH2_k127_4756461_3 Histidine kinase K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006735 258.0
PYH2_k127_4756461_4 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000001742 178.0
PYH2_k127_4763249_0 - - - - 2.535e-227 720.0
PYH2_k127_4763249_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 471.0
PYH2_k127_4763249_2 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 293.0
PYH2_k127_4763249_3 PFAM Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000004168 211.0
PYH2_k127_4763249_4 LysR substrate binding domain K03566 - - 0.00000001073 57.0
PYH2_k127_4763249_5 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit - - - 0.0000000615 64.0
PYH2_k127_4805659_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1511.0
PYH2_k127_4805659_1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 3.219e-197 617.0
PYH2_k127_4805659_2 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 548.0
PYH2_k127_4805659_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 527.0
PYH2_k127_4805659_4 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 397.0
PYH2_k127_4805659_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 389.0
PYH2_k127_4805659_6 Nudix N-terminal K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000001615 272.0
PYH2_k127_4805659_7 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000006653 137.0
PYH2_k127_4805659_8 Phage integrase family - - - 0.000001209 58.0
PYH2_k127_4806016_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.0 1159.0
PYH2_k127_4806016_1 Gluconolactonase K01053,K14274 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 554.0
PYH2_k127_4806016_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 325.0
PYH2_k127_4806016_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 309.0
PYH2_k127_4806016_4 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000008324 79.0
PYH2_k127_4815640_0 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 469.0
PYH2_k127_4815640_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 374.0
PYH2_k127_4815640_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 355.0
PYH2_k127_4815640_3 NAD binding K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 314.0
PYH2_k127_4815640_4 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000005984 249.0
PYH2_k127_4815640_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001886 237.0
PYH2_k127_4815640_6 - - - - 0.0000000000000307 76.0
PYH2_k127_4815640_7 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.00000003533 63.0
PYH2_k127_4816528_0 PFAM MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 528.0
PYH2_k127_4816528_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 390.0
PYH2_k127_4820823_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 4.215e-233 728.0
PYH2_k127_4820823_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 7.366e-196 616.0
PYH2_k127_4820823_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 356.0
PYH2_k127_4820823_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000006908 72.0
PYH2_k127_4823731_0 Thioredoxin-like K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 431.0
PYH2_k127_4823731_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000745 269.0
PYH2_k127_4825612_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1319.0
PYH2_k127_4825612_1 His Kinase A (phosphoacceptor) domain - - - 0.0 1268.0
PYH2_k127_4825612_10 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 447.0
PYH2_k127_4825612_11 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 315.0
PYH2_k127_4825612_12 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006074 257.0
PYH2_k127_4825612_13 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001505 258.0
PYH2_k127_4825612_14 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000003364 228.0
PYH2_k127_4825612_15 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000008235 221.0
PYH2_k127_4825612_16 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000001248 211.0
PYH2_k127_4825612_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000000000000002925 186.0
PYH2_k127_4825612_18 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000001402 182.0
PYH2_k127_4825612_19 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000000002772 139.0
PYH2_k127_4825612_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1123.0
PYH2_k127_4825612_20 rRNA methyltransferase K03437 - - 0.00000000000000000000000000000003394 126.0
PYH2_k127_4825612_21 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000003313 121.0
PYH2_k127_4825612_22 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000000000001954 109.0
PYH2_k127_4825612_23 - - - - 0.0000000000000004815 81.0
PYH2_k127_4825612_24 - - - - 0.00000000001892 72.0
PYH2_k127_4825612_3 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1103.0
PYH2_k127_4825612_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.565e-286 898.0
PYH2_k127_4825612_5 sulfatase - - - 5.454e-281 878.0
PYH2_k127_4825612_6 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.015e-228 730.0
PYH2_k127_4825612_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 6.128e-212 662.0
PYH2_k127_4825612_8 EXOIII K02342 - 2.7.7.7 8.897e-211 679.0
PYH2_k127_4825612_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 552.0
PYH2_k127_4827882_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.132e-269 859.0
PYH2_k127_4827882_1 Protein of unknown function (DUF3419) K13622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 379.0
PYH2_k127_4827882_2 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000004676 263.0
PYH2_k127_4827882_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000016 53.0
PYH2_k127_4830923_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 498.0
PYH2_k127_4830923_1 Peptidase M15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009548 244.0
PYH2_k127_4830923_2 Ketosteroid isomerase-related protein - - - 0.0000000000000000001047 93.0
PYH2_k127_4830923_3 - - - - 0.0005464 46.0
PYH2_k127_4834678_0 ABC transporter, transmembrane region K06147 - - 5.103e-287 897.0
PYH2_k127_4834678_1 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003564 273.0
PYH2_k127_4834678_2 Lipocalin-like domain - - - 0.00000000000000000000000000000000000001172 145.0
PYH2_k127_4849496_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.937e-242 757.0
PYH2_k127_4849496_1 PFAM multicopper oxidase type 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 347.0
PYH2_k127_4849496_2 - - - - 0.0000000000322 70.0
PYH2_k127_485920_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1569.0
PYH2_k127_485920_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 413.0
PYH2_k127_485920_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 308.0
PYH2_k127_485920_3 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000006473 266.0
PYH2_k127_485920_4 PFAM Membrane protein of K08972 - - 0.0000000000000000000000000000000000000000000002853 172.0
PYH2_k127_485920_5 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000000000000018 171.0
PYH2_k127_485920_7 membrane protein TerC K05794 - - 0.0000000000000000000000005885 107.0
PYH2_k127_485920_8 Peptidase family M48 - - - 0.000000000000000000000007396 104.0
PYH2_k127_4903038_0 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 5.067e-207 652.0
PYH2_k127_4903038_1 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 343.0
PYH2_k127_4903674_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147 - 3.1.13.1 8.995e-229 717.0
PYH2_k127_4903674_1 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 457.0
PYH2_k127_4903674_2 DnaJ C terminal domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 394.0
PYH2_k127_4903674_3 Phospholipid N-methyltransferase - - - 0.0000000000000000000000000000000756 136.0
PYH2_k127_4903674_4 MerR HTH family regulatory protein K18997 - - 0.0000000000000000000000000614 112.0
PYH2_k127_4903674_6 MacB-like periplasmic core domain K02004 - - 0.000001142 56.0
PYH2_k127_4929818_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.785e-250 775.0
PYH2_k127_4929818_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
PYH2_k127_4929818_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 296.0
PYH2_k127_4929818_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000000000002082 133.0
PYH2_k127_4929818_4 Nicotinamide mononucleotide transporter K03811 - - 0.000000232 53.0
PYH2_k127_4944607_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 2.466e-197 636.0
PYH2_k127_4944607_1 ABC transporter K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 472.0
PYH2_k127_4944607_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000002084 85.0
PYH2_k127_4948037_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 471.0
PYH2_k127_4948037_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000003695 149.0
PYH2_k127_4948037_2 DNA alkylation repair - - - 0.000000000000000000000000000000003518 130.0
PYH2_k127_4951176_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 3.757e-243 754.0
PYH2_k127_4951176_1 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 433.0
PYH2_k127_4951176_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 411.0
PYH2_k127_4951176_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 302.0
PYH2_k127_496451_0 Acetate kinase K00925 - 2.7.2.1 1.208e-241 759.0
PYH2_k127_496451_1 Homospermidine synthase K00808 - 2.5.1.44 1.839e-205 648.0
PYH2_k127_496451_2 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000004008 247.0
PYH2_k127_497096_0 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 469.0
PYH2_k127_497096_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000002497 180.0
PYH2_k127_497096_2 DoxX K15977 - - 0.0000000000000000000000000000000002899 136.0
PYH2_k127_497096_3 PGAP1-like protein - - - 0.00000000000000000000007049 112.0
PYH2_k127_497096_4 PFAM regulatory protein GntR HTH - - - 0.0000000000000000000001238 111.0
PYH2_k127_497096_5 Sulfite exporter TauE/SafE - - - 0.0000009727 54.0
PYH2_k127_4982984_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
PYH2_k127_4982984_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000001665 214.0
PYH2_k127_4982984_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000005386 157.0
PYH2_k127_4982984_3 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000005865 154.0
PYH2_k127_4982984_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000002154 98.0
PYH2_k127_4995234_0 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.0 1259.0
PYH2_k127_4995234_1 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 0.0 1105.0
PYH2_k127_4995234_10 Succinate dehydrogenase cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000007196 217.0
PYH2_k127_4995234_11 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000000000009167 118.0
PYH2_k127_4995234_12 Dodecin K09165 - - 0.000000000000000000000002068 104.0
PYH2_k127_4995234_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1069.0
PYH2_k127_4995234_3 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 9.568e-311 973.0
PYH2_k127_4995234_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.397e-268 828.0
PYH2_k127_4995234_5 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 523.0
PYH2_k127_4995234_6 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 458.0
PYH2_k127_4995234_7 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 339.0
PYH2_k127_4995234_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 287.0
PYH2_k127_4995234_9 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.000000000000000000000000000000000000000000000000000000000000000795 220.0
PYH2_k127_5006380_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 5.776e-222 702.0
PYH2_k127_5006380_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 599.0
PYH2_k127_5006380_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000021 143.0
PYH2_k127_5006380_11 Endoribonuclease L-PSP - - - 0.000000000000000000000000000003446 125.0
PYH2_k127_5006380_12 - - - - 0.0000000000000000000000000007102 125.0
PYH2_k127_5006380_13 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000756 103.0
PYH2_k127_5006380_2 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 583.0
PYH2_k127_5006380_3 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 502.0
PYH2_k127_5006380_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 474.0
PYH2_k127_5006380_5 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 471.0
PYH2_k127_5006380_6 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 373.0
PYH2_k127_5006380_7 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 318.0
PYH2_k127_5006380_8 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004646 257.0
PYH2_k127_5006380_9 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000004347 154.0
PYH2_k127_5016748_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 368.0
PYH2_k127_5016748_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000004661 253.0
PYH2_k127_5037472_0 Major facilitator superfamily K05939 - 2.3.1.40,6.2.1.20 8.135e-305 945.0
PYH2_k127_5037472_1 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 384.0
PYH2_k127_5037472_10 Pfam:AmoA K07120 - - 0.0000000000001171 78.0
PYH2_k127_5037472_11 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.000000007512 61.0
PYH2_k127_5037472_12 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00001744 53.0
PYH2_k127_5037472_2 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 319.0
PYH2_k127_5037472_3 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003282 267.0
PYH2_k127_5037472_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002822 264.0
PYH2_k127_5037472_5 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000001439 231.0
PYH2_k127_5037472_6 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.000000000000000000000000000000000000000000000000000000001311 212.0
PYH2_k127_5037472_7 Ammonia monooxygenase K07120 - - 0.00000000000000000000000000000000000000000000001743 183.0
PYH2_k127_5037472_8 - - - - 0.0000000000000000000000000000000000000842 147.0
PYH2_k127_5037472_9 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000001884 98.0
PYH2_k127_5081468_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 453.0
PYH2_k127_5081468_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 366.0
PYH2_k127_5086333_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.865e-288 889.0
PYH2_k127_5108736_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 418.0
PYH2_k127_5108736_1 LemA family - - - 0.00000000000000000000000000000000000000000003346 166.0
PYH2_k127_5116180_0 FtsX-like permease family K02004 - - 0.0 1122.0
PYH2_k127_5116180_1 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 504.0
PYH2_k127_5116180_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 408.0
PYH2_k127_5116180_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 389.0
PYH2_k127_5116180_4 Type ii and iii secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000007373 213.0
PYH2_k127_5116180_5 Universal stress protein - - - 0.000000000000000000000002892 107.0
PYH2_k127_5130632_0 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 520.0
PYH2_k127_5130632_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 441.0
PYH2_k127_5130632_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 424.0
PYH2_k127_5130632_3 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001487 274.0
PYH2_k127_5132642_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.259e-199 629.0
PYH2_k127_5132642_1 Outer membrane protein beta-barrel family K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000001859 242.0
PYH2_k127_5132642_2 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000002077 145.0
PYH2_k127_5158779_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.0 1074.0
PYH2_k127_5158779_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.173e-315 972.0
PYH2_k127_5158779_10 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 439.0
PYH2_k127_5158779_11 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 383.0
PYH2_k127_5158779_12 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 380.0
PYH2_k127_5158779_13 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 348.0
PYH2_k127_5158779_14 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 312.0
PYH2_k127_5158779_15 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 306.0
PYH2_k127_5158779_16 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005605 269.0
PYH2_k127_5158779_17 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
PYH2_k127_5158779_18 TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.000000000000000000000000000000000000000000000000000000000000000000001227 240.0
PYH2_k127_5158779_19 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
PYH2_k127_5158779_2 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02504,K02652 - - 5.744e-307 947.0
PYH2_k127_5158779_20 phenylacetic acid degradation protein PaaD K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000000000000000000000000000008674 222.0
PYH2_k127_5158779_21 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000108 187.0
PYH2_k127_5158779_22 TIGRFAM phenylacetate-CoA oxygenase, PaaH subunit K02610 - - 0.000000000000000000000000000000000000000000000000001121 183.0
PYH2_k127_5158779_23 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000008543 175.0
PYH2_k127_5158779_24 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000303 144.0
PYH2_k127_5158779_25 - - - - 0.000000000000000000000000006225 118.0
PYH2_k127_5158779_26 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000249 89.0
PYH2_k127_5158779_27 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000001219 72.0
PYH2_k127_5158779_28 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000001582 59.0
PYH2_k127_5158779_29 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186,K16875 - 2.5.1.129 0.0000002052 55.0
PYH2_k127_5158779_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.809e-242 752.0
PYH2_k127_5158779_30 - - - - 0.0004217 42.0
PYH2_k127_5158779_4 Type II secretion system K02653 - - 9.157e-210 657.0
PYH2_k127_5158779_5 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 2.718e-194 608.0
PYH2_k127_5158779_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 609.0
PYH2_k127_5158779_7 TIGRFAM phenylacetate-CoA oxygenase reductase, PaaK subunit K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 606.0
PYH2_k127_5158779_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 593.0
PYH2_k127_5158779_9 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 485.0
PYH2_k127_5159558_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 8.499e-222 702.0
PYH2_k127_517178_0 Dehydrogenase K15515 - 1.2.1.81 2.783e-208 654.0
PYH2_k127_517178_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 438.0
PYH2_k127_5193188_0 Cysteine-rich domain - - - 1.239e-263 815.0
PYH2_k127_5193188_1 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 403.0
PYH2_k127_5193188_10 Bacterioferritin K03594 - 1.16.3.1 0.000000000000000000000000000005237 128.0
PYH2_k127_5193188_11 Rubrerythrin - - - 0.000000000000000002562 94.0
PYH2_k127_5193188_12 response regulator K02282,K07705 - - 0.000000000001934 75.0
PYH2_k127_5193188_13 hyperosmotic response - - - 0.00000000001307 72.0
PYH2_k127_5193188_14 Belongs to the UPF0337 (CsbD) family - - - 0.0000000002698 65.0
PYH2_k127_5193188_15 - - - - 0.0001609 47.0
PYH2_k127_5193188_2 Carboxylesterase family K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 374.0
PYH2_k127_5193188_3 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000762 299.0
PYH2_k127_5193188_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004734 274.0
PYH2_k127_5193188_5 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
PYH2_k127_5193188_6 Histidine kinase K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000001544 221.0
PYH2_k127_5193188_7 - - - - 0.000000000000000000000000000000000000000000000000009973 186.0
PYH2_k127_5193188_8 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000004845 148.0
PYH2_k127_5193188_9 BON domain K04065 - - 0.00000000000000000000000000000000131 133.0
PYH2_k127_5202263_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 543.0
PYH2_k127_5202263_1 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 366.0
PYH2_k127_5240649_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 378.0
PYH2_k127_5240649_1 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000001746 254.0
PYH2_k127_5240649_2 Protein of unknown function (DUF3443) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001659 249.0
PYH2_k127_5240649_3 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000001671 157.0
PYH2_k127_5240649_4 TonB C terminal - - - 0.000000000000000000000000000002652 124.0
PYH2_k127_5240649_5 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000001189 98.0
PYH2_k127_5240649_6 Protein of unknown function (DUF2844) - - - 0.00000000000002208 81.0
PYH2_k127_5271399_0 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 444.0
PYH2_k127_5271399_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 389.0
PYH2_k127_5271399_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 363.0
PYH2_k127_5271399_3 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000527 247.0
PYH2_k127_5277505_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.114e-198 629.0
PYH2_k127_5277505_1 SMP-30 Gluconolaconase K13874,K14274 - 3.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 411.0
PYH2_k127_5277505_2 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 379.0
PYH2_k127_5277505_3 related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 369.0
PYH2_k127_5277505_4 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 284.0
PYH2_k127_5277505_5 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004429 246.0
PYH2_k127_5277505_6 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000009197 212.0
PYH2_k127_5277505_7 PFAM Cytochrome C - - - 0.0000000000000000000000000000000000000000000000001718 181.0
PYH2_k127_5279862_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003406 283.0
PYH2_k127_5279862_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000007201 204.0
PYH2_k127_5279862_2 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.000000000000000000000368 102.0
PYH2_k127_5279862_3 Adenylate K01768 - 4.6.1.1 0.000000000000003649 79.0
PYH2_k127_5279862_4 - - - - 0.000002399 59.0
PYH2_k127_528811_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1654.0
PYH2_k127_528811_1 acetolactate synthase K01652 - 2.2.1.6 0.0 1074.0
PYH2_k127_528811_10 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 416.0
PYH2_k127_528811_11 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 406.0
PYH2_k127_528811_12 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 354.0
PYH2_k127_528811_13 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 351.0
PYH2_k127_528811_14 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 352.0
PYH2_k127_528811_15 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 311.0
PYH2_k127_528811_16 synthase small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 302.0
PYH2_k127_528811_17 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000001164 252.0
PYH2_k127_528811_18 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000000000000000001128 153.0
PYH2_k127_528811_19 Protein of unknown function (DUF3619) - - - 0.000000000000000000000000000001337 127.0
PYH2_k127_528811_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.536e-287 890.0
PYH2_k127_528811_20 - - - - 0.00004098 46.0
PYH2_k127_528811_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.293e-248 770.0
PYH2_k127_528811_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.42e-209 659.0
PYH2_k127_528811_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.078e-195 613.0
PYH2_k127_528811_6 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 464.0
PYH2_k127_528811_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 452.0
PYH2_k127_528811_8 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 448.0
PYH2_k127_528811_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 429.0
PYH2_k127_5288788_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1130.0
PYH2_k127_5288788_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.348e-270 842.0
PYH2_k127_5288788_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 538.0
PYH2_k127_5288788_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 483.0
PYH2_k127_5288788_4 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000000006163 192.0
PYH2_k127_5288788_5 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000004207 188.0
PYH2_k127_5288788_6 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000006505 172.0
PYH2_k127_5288788_7 GyrI-like small molecule binding domain - - - 0.00000000000001479 78.0
PYH2_k127_5288788_8 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000007293 61.0
PYH2_k127_529043_0 aminopeptidase N K01256 - 3.4.11.2 0.0 1308.0
PYH2_k127_529043_1 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000005458 178.0
PYH2_k127_5324248_0 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 487.0
PYH2_k127_5324248_1 Transcriptional regulator, MarR family with acetyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003073 224.0
PYH2_k127_5324248_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000001691 221.0
PYH2_k127_5324248_3 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.000000000000000000000000000000000000000000000000003168 197.0
PYH2_k127_5324248_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000004689 107.0
PYH2_k127_5324569_0 ABC transporter K06147 - - 1.752e-286 893.0
PYH2_k127_5324569_1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 385.0
PYH2_k127_5324569_2 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001239 282.0
PYH2_k127_5324569_3 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000000000000000000007966 209.0
PYH2_k127_5326501_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 9.112e-233 730.0
PYH2_k127_5326501_1 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 579.0
PYH2_k127_5326501_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 443.0
PYH2_k127_5326501_3 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 439.0
PYH2_k127_5326501_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
PYH2_k127_5326501_5 Pyridoxamine 5'-phosphate oxidase like - - - 0.00000000000000000000000000000000000000000000000000009066 194.0
PYH2_k127_5326501_6 SNARE associated Golgi protein - - - 0.000009376 56.0
PYH2_k127_5329693_0 Flagellar hook protein FlgE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 609.0
PYH2_k127_5329693_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 512.0
PYH2_k127_5329693_10 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000001414 176.0
PYH2_k127_5329693_11 - - - - 0.0000000000000000000000004903 109.0
PYH2_k127_5329693_12 mercury ion transmembrane transporter activity K07089,K07213 - - 0.0000000000000001544 81.0
PYH2_k127_5329693_13 anti-sigma-28 factor K02398 - - 0.0000000000003125 73.0
PYH2_k127_5329693_2 flagellar basal-body rod protein K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 423.0
PYH2_k127_5329693_3 flagellar hook-associated protein K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 400.0
PYH2_k127_5329693_4 Flagellar basal-body rod protein FlgF K02391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 353.0
PYH2_k127_5329693_5 TIGRFAM flagellar rod assembly protein muramidase FlgJ K02395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 300.0
PYH2_k127_5329693_6 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001001 282.0
PYH2_k127_5329693_7 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000000000000000000004521 223.0
PYH2_k127_5329693_8 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000000000000000000000000000000000000000000000000003588 213.0
PYH2_k127_5329693_9 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000000000000000006998 205.0
PYH2_k127_5330350_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 1.212e-196 625.0
PYH2_k127_5330350_1 PFAM Aminotransferase class I and II K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 608.0
PYH2_k127_5330350_2 Transcriptional regulator, LysR family K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 530.0
PYH2_k127_5330350_3 Permease, YjgP YjgQ K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 509.0
PYH2_k127_5330350_4 Permease, YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 474.0
PYH2_k127_5330350_5 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003855 278.0
PYH2_k127_5330350_6 CbiX K03795 - 4.99.1.3 0.0000000000000000000000000000000000002566 145.0
PYH2_k127_5330350_7 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0002795 52.0
PYH2_k127_5335667_0 PFAM amidohydrolase K01464,K01466 - 3.5.2.2,3.5.2.5 1.205e-273 858.0
PYH2_k127_5335667_1 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 447.0
PYH2_k127_5335667_2 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000009089 236.0
PYH2_k127_5335667_3 Homoaconitate hydratase family protein K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000001501 124.0
PYH2_k127_5344530_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1394.0
PYH2_k127_5344530_1 Helicase K03657 - 3.6.4.12 0.0 1250.0
PYH2_k127_5344530_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000009336 106.0
PYH2_k127_5344530_11 - - - - 0.0000000000000000245 85.0
PYH2_k127_5344530_12 - - - - 0.0000000479 60.0
PYH2_k127_5344530_2 Rieske 2Fe-2S K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 604.0
PYH2_k127_5344530_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 529.0
PYH2_k127_5344530_4 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 470.0
PYH2_k127_5344530_5 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 387.0
PYH2_k127_5344530_6 Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 367.0
PYH2_k127_5344530_7 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 336.0
PYH2_k127_5344530_8 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001079 224.0
PYH2_k127_5344530_9 - - - - 0.0000000000000000000000000000000000000000000000000000000002167 218.0
PYH2_k127_5372088_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 601.0
PYH2_k127_5372088_1 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000000000000000001855 215.0
PYH2_k127_5372088_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000007447 173.0
PYH2_k127_5383_0 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 512.0
PYH2_k127_5383_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000001216 233.0
PYH2_k127_5397083_0 PFAM extracellular solute-binding protein family 1 K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 530.0
PYH2_k127_5397083_1 binding-protein-dependent transport systems inner membrane component K02054 - - 0.00000000000000000000002324 104.0
PYH2_k127_5397083_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000101 65.0
PYH2_k127_540559_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 4.59e-223 696.0
PYH2_k127_540559_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 1.635e-195 621.0
PYH2_k127_540559_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 600.0
PYH2_k127_540559_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 350.0
PYH2_k127_540559_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000006524 183.0
PYH2_k127_5409511_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 9.081e-271 840.0
PYH2_k127_542917_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 528.0
PYH2_k127_542917_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 402.0
PYH2_k127_542917_2 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 306.0
PYH2_k127_542917_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000001765 71.0
PYH2_k127_5440885_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1148.0
PYH2_k127_5440885_1 Belongs to the IlvD Edd family K01687,K13875,K22186 - 4.2.1.25,4.2.1.82,4.2.1.9 0.0 1006.0
PYH2_k127_5440885_2 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 479.0
PYH2_k127_5440885_3 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 421.0
PYH2_k127_5440885_4 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 420.0
PYH2_k127_5440885_5 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 412.0
PYH2_k127_5440885_6 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006838 278.0
PYH2_k127_5440885_7 CsbD-like - - - 0.00000000000000000000000000000000000672 138.0
PYH2_k127_5440885_8 SMART Transport-associated and nodulation region K04065 - - 0.00000000000000000000000000000000001093 139.0
PYH2_k127_5450343_0 major facilitator superfamily K03446 - - 6.286e-248 778.0
PYH2_k127_5450343_1 secretion protein HlyD family K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 510.0
PYH2_k127_5450343_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 434.0
PYH2_k127_5450343_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
PYH2_k127_5464822_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 1.164e-196 619.0
PYH2_k127_5464822_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 384.0
PYH2_k127_5464822_2 LemA family K03744 - - 0.00000000000000002028 88.0
PYH2_k127_5473073_0 alcohol dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 530.0
PYH2_k127_5473073_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000008842 143.0
PYH2_k127_5473073_2 sequence-specific DNA binding K07726 - - 0.00000000000000000000000004046 107.0
PYH2_k127_5473073_3 - - - - 0.0000000000000003253 81.0
PYH2_k127_5480847_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1114.0
PYH2_k127_5480847_1 Belongs to the thiolase family K00626 - 2.3.1.9 6.45e-211 661.0
PYH2_k127_5480847_2 PFAM NUDIX hydrolase - - - 7.453e-211 669.0
PYH2_k127_5480847_3 PFAM aldo keto reductase K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 419.0
PYH2_k127_5480847_4 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000008044 250.0
PYH2_k127_5480847_5 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000000000000000679 177.0
PYH2_k127_5487819_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.378e-196 631.0
PYH2_k127_5487819_1 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 377.0
PYH2_k127_5487819_2 Polyhydroxyalkanoate synthesis repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002355 275.0
PYH2_k127_5487819_3 Phage integrase family - - - 0.000000000000000000008899 95.0
PYH2_k127_5516392_0 TonB-dependent receptor plug K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 482.0
PYH2_k127_5516392_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000002201 230.0
PYH2_k127_5516392_2 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000007498 213.0
PYH2_k127_5516392_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000001195 126.0
PYH2_k127_5516392_4 - - - - 0.000000000000000001517 97.0
PYH2_k127_5525940_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1133.0
PYH2_k127_5525940_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 343.0
PYH2_k127_5525940_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 311.0
PYH2_k127_5525940_3 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000001747 217.0
PYH2_k127_5525940_4 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000227 188.0
PYH2_k127_5525940_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000003698 128.0
PYH2_k127_5525940_6 Aldo/keto reductase family K05882 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008152,GO:0009987,GO:0015672,GO:0016491,GO:0017144,GO:0030001,GO:0034220,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071704,GO:0071804,GO:0071805,GO:0072527,GO:0098655,GO:0098660,GO:0098662,GO:1901360,GO:1901564 1.1.1.91 0.00000000000007735 72.0
PYH2_k127_5583978_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 591.0
PYH2_k127_5583978_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 593.0
PYH2_k127_5583978_2 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 555.0
PYH2_k127_5583978_3 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008369 284.0
PYH2_k127_5583978_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000008882 123.0
PYH2_k127_5584049_0 Cytochrome D1 heme domain - - - 7.098e-278 861.0
PYH2_k127_5584049_1 Radical SAM - - - 2.158e-205 643.0
PYH2_k127_5584049_2 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 443.0
PYH2_k127_5584049_3 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 334.0
PYH2_k127_5584049_4 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003925 254.0
PYH2_k127_5584049_5 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000006652 192.0
PYH2_k127_5599113_0 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.554e-219 681.0
PYH2_k127_5599113_1 MmgE/PrpD family - - - 8.65e-206 648.0
PYH2_k127_5599113_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 466.0
PYH2_k127_5599113_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000009137 196.0
PYH2_k127_5599113_4 Protein of unknown function (DUF3307) - - - 0.0000000000000000000000000000006122 126.0
PYH2_k127_5609634_0 Oxidoreductase domain protein - - - 1.454e-257 813.0
PYH2_k127_5609634_1 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 512.0
PYH2_k127_5609634_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 293.0
PYH2_k127_5609634_3 Cytochrome c - - - 0.000000000000000000000000000003425 126.0
PYH2_k127_5609634_4 PFAM 5-nucleotidase K01081 - 3.1.3.5 0.0000002718 59.0
PYH2_k127_5613361_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1050.0
PYH2_k127_5613361_1 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 8.408e-285 902.0
PYH2_k127_5613361_10 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 517.0
PYH2_k127_5613361_11 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 417.0
PYH2_k127_5613361_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 357.0
PYH2_k127_5613361_13 Peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 359.0
PYH2_k127_5613361_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000006096 276.0
PYH2_k127_5613361_15 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001335 256.0
PYH2_k127_5613361_16 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
PYH2_k127_5613361_17 - - - - 0.000000000000000000000000000000000000000000000000000000000001231 218.0
PYH2_k127_5613361_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000239 196.0
PYH2_k127_5613361_19 transcriptional regulator - - - 0.0007598 50.0
PYH2_k127_5613361_2 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 4.208e-281 895.0
PYH2_k127_5613361_3 ABC-type dipeptide transport system, periplasmic component - - - 2.041e-261 835.0
PYH2_k127_5613361_4 AMP-binding enzyme K01897 - 6.2.1.3 4.211e-256 800.0
PYH2_k127_5613361_5 Acetyl-coenzyme A transporter 1 K08218 - - 6.796e-251 782.0
PYH2_k127_5613361_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.159e-215 679.0
PYH2_k127_5613361_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.656e-201 653.0
PYH2_k127_5613361_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 520.0
PYH2_k127_5613361_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 505.0
PYH2_k127_5617911_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1133.0
PYH2_k127_5617911_1 Pyridine nucleotide-disulphide oxidoreductase - - - 3.181e-208 654.0
PYH2_k127_5617911_10 - - - - 0.0000000000000000000000001954 109.0
PYH2_k127_5617911_11 - - - - 0.00000000000000000005391 94.0
PYH2_k127_5617911_2 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 431.0
PYH2_k127_5617911_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 427.0
PYH2_k127_5617911_4 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 395.0
PYH2_k127_5617911_5 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 360.0
PYH2_k127_5617911_6 Diguanylate cyclase with PAS PAC sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 362.0
PYH2_k127_5617911_7 4Fe-4S dicluster domain K05796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 336.0
PYH2_k127_5617911_8 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000001413 125.0
PYH2_k127_5617911_9 Mut7-C ubiquitin - - - 0.00000000000000000000000000001685 119.0
PYH2_k127_5635349_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1464.0
PYH2_k127_5635349_1 Belongs to the TPP enzyme family K04103 - 4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 496.0
PYH2_k127_5638861_0 PFAM amidohydrolase K01464 - 3.5.2.2 1.501e-271 841.0
PYH2_k127_5638861_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K17723,K17828 - 1.3.1.1,1.3.1.14 1.596e-240 748.0
PYH2_k127_5638861_2 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 1.476e-238 767.0
PYH2_k127_5638861_3 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 394.0
PYH2_k127_5638861_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17722 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 366.0
PYH2_k127_565678_0 Kelch motif - - - 0.0000000000000000000000000000000000000001421 164.0
PYH2_k127_565678_1 - - - - 0.0000000000000000000000000000000000169 144.0
PYH2_k127_5659942_0 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 477.0
PYH2_k127_5659942_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 478.0
PYH2_k127_5659942_2 luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 358.0
PYH2_k127_5659942_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000419 135.0
PYH2_k127_5659942_4 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000000000006096 136.0
PYH2_k127_5665764_0 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 481.0
PYH2_k127_5665764_1 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004075 280.0
PYH2_k127_5665764_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000183 265.0
PYH2_k127_5665764_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002795 242.0
PYH2_k127_5665764_4 PBP superfamily domain K07219 - - 0.000000000000000000000000000000000000000000000000000000000000002534 220.0
PYH2_k127_5692573_0 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001763 277.0
PYH2_k127_5692573_1 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006334 246.0
PYH2_k127_5699794_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 604.0
PYH2_k127_5699794_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 587.0
PYH2_k127_5699794_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000231 197.0
PYH2_k127_5699794_11 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000001651 194.0
PYH2_k127_5699794_12 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000005772 154.0
PYH2_k127_5699794_13 VanZ like family - - - 0.00000000000000000000000000000001936 130.0
PYH2_k127_5699794_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 550.0
PYH2_k127_5699794_3 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 499.0
PYH2_k127_5699794_4 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 463.0
PYH2_k127_5699794_5 PFAM alanine racemase domain protein K19967 - 4.1.2.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 462.0
PYH2_k127_5699794_6 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 361.0
PYH2_k127_5699794_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 367.0
PYH2_k127_5699794_8 Formate nitrite K02598,K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 339.0
PYH2_k127_5699794_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003111 278.0
PYH2_k127_5706423_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 4.255e-228 716.0
PYH2_k127_5706423_1 RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 351.0
PYH2_k127_5706423_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 305.0
PYH2_k127_5706423_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000002065 228.0
PYH2_k127_5706423_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000002399 165.0
PYH2_k127_5706423_5 PFAM Thiamine pyrophosphate K00170,K18356 - 1.2.1.58,1.2.7.1 0.00000000000000000001925 91.0
PYH2_k127_5706423_6 - - - - 0.00000000001233 70.0
PYH2_k127_5758157_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.139e-254 795.0
PYH2_k127_5758157_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 449.0
PYH2_k127_5758157_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 379.0
PYH2_k127_5758157_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000838 267.0
PYH2_k127_5758157_4 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000004019 207.0
PYH2_k127_575922_0 Histidine kinase-like ATPases - - - 3.096e-264 834.0
PYH2_k127_575922_1 transcriptional regulator, SARP family - - - 0.0002174 54.0
PYH2_k127_5777011_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 579.0
PYH2_k127_5780354_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.111e-258 799.0
PYH2_k127_5780354_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 1.232e-247 778.0
PYH2_k127_5780354_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 286.0
PYH2_k127_5780354_11 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001506 271.0
PYH2_k127_5780354_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001422 257.0
PYH2_k127_5780354_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 255.0
PYH2_k127_5780354_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008459 237.0
PYH2_k127_5780354_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000002402 236.0
PYH2_k127_5780354_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000000001023 231.0
PYH2_k127_5780354_17 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000001269 220.0
PYH2_k127_5780354_18 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000002259 216.0
PYH2_k127_5780354_19 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000002715 183.0
PYH2_k127_5780354_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 610.0
PYH2_k127_5780354_20 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000003023 175.0
PYH2_k127_5780354_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000000000001384 169.0
PYH2_k127_5780354_22 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000000224 149.0
PYH2_k127_5780354_23 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000002346 145.0
PYH2_k127_5780354_24 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000000279 102.0
PYH2_k127_5780354_25 Ribosomal protein L30 K02907 - - 0.0000000000000000000006735 99.0
PYH2_k127_5780354_26 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000002608 75.0
PYH2_k127_5780354_27 - - - - 0.00000000005891 63.0
PYH2_k127_5780354_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 606.0
PYH2_k127_5780354_4 membrane-associated Zn-dependent proteases 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 550.0
PYH2_k127_5780354_5 Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 464.0
PYH2_k127_5780354_6 Transport permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 373.0
PYH2_k127_5780354_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 364.0
PYH2_k127_5780354_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 331.0
PYH2_k127_5780354_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 292.0
PYH2_k127_5781841_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 368.0
PYH2_k127_5781841_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 322.0
PYH2_k127_5781841_2 50S ribosomal protein L4 K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 293.0
PYH2_k127_5781841_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000001289 196.0
PYH2_k127_5781841_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000003437 152.0
PYH2_k127_5781841_5 translation elongation factor activity K02358 - - 0.000000000000000000000001079 103.0
PYH2_k127_5797259_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 9.279e-319 982.0
PYH2_k127_5797259_1 Protein of unknown function (DUF2868) - - - 0.0009086 50.0
PYH2_k127_5800546_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.692e-267 833.0
PYH2_k127_5800546_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.34e-212 664.0
PYH2_k127_5800546_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 453.0
PYH2_k127_5800546_3 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001374 232.0
PYH2_k127_5800546_4 Protein of unknown function (DUF2788) - - - 0.000000000000000000000000000324 122.0
PYH2_k127_5800546_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000001014 89.0
PYH2_k127_5812151_0 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 565.0
PYH2_k127_5812151_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 380.0
PYH2_k127_5812151_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001346 259.0
PYH2_k127_5812151_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000005704 198.0
PYH2_k127_5812151_4 ACT domain K09707 - - 0.000000000000000000000000000003194 123.0
PYH2_k127_5812151_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000007394 63.0
PYH2_k127_5816191_0 Glycosyl transferase family 41 - - - 1.243e-227 723.0
PYH2_k127_5816191_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 542.0
PYH2_k127_5816191_2 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 481.0
PYH2_k127_5816191_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 376.0
PYH2_k127_5816191_4 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 374.0
PYH2_k127_5816191_5 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 295.0
PYH2_k127_5816191_6 flagellar protein FliS K02422 - - 0.00000000000000000000000000000000000000000000002397 175.0
PYH2_k127_5816191_7 Flagellar protein FliT K02423 - - 0.000000000000000000000000000000000000002072 150.0
PYH2_k127_5816191_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000001575 120.0
PYH2_k127_5816428_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1107.0
PYH2_k127_5816428_1 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 486.0
PYH2_k127_5816428_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 319.0
PYH2_k127_5816428_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000005364 218.0
PYH2_k127_5816428_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000000001823 210.0
PYH2_k127_5816428_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000000003878 131.0
PYH2_k127_5816428_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000005125 102.0
PYH2_k127_5816991_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.264e-210 666.0
PYH2_k127_5816991_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 490.0
PYH2_k127_5816991_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 472.0
PYH2_k127_5816991_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 439.0
PYH2_k127_5816991_4 cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 301.0
PYH2_k127_5816991_5 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.0000000000000000000000000000000000000000000000000000005326 201.0
PYH2_k127_5816991_6 Pfam cytochrome c K08738 - - 0.0000000000000000000000000205 112.0
PYH2_k127_5825446_0 protein-(glutamine-N5) methyltransferase activity K21786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 368.0
PYH2_k127_5825446_1 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000005106 132.0
PYH2_k127_5825446_2 - - - - 0.000002336 59.0
PYH2_k127_5833301_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 3.701e-245 766.0
PYH2_k127_5833301_1 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 304.0
PYH2_k127_5833301_2 Domain of Unknown Function (DUF350) - - - 0.000000000000000000000000000000003275 129.0
PYH2_k127_5838665_0 Thermolysin metallopeptidase, alpha-helical domain K20273 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 414.0
PYH2_k127_5838665_1 Major Facilitator Superfamily K19577 - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
PYH2_k127_5851977_0 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 452.0
PYH2_k127_5851977_1 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000007747 238.0
PYH2_k127_5851977_2 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000003372 190.0
PYH2_k127_5860199_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 573.0
PYH2_k127_5860199_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 401.0
PYH2_k127_5860199_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 333.0
PYH2_k127_5860199_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 329.0
PYH2_k127_5860199_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 310.0
PYH2_k127_5860199_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 286.0
PYH2_k127_5860199_6 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000001106 154.0
PYH2_k127_5860199_7 Methyltransferase K08316 - 2.1.1.171 0.000000000003697 68.0
PYH2_k127_5860199_8 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000009453 63.0
PYH2_k127_5860631_0 CoA binding domain - - - 0.0 1200.0
PYH2_k127_5860631_1 Tripartite tricarboxylate transporter TctA family K07793 - - 4.124e-273 847.0
PYH2_k127_5860631_10 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 396.0
PYH2_k127_5860631_11 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 320.0
PYH2_k127_5860631_12 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 302.0
PYH2_k127_5860631_13 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 304.0
PYH2_k127_5860631_14 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001382 269.0
PYH2_k127_5860631_15 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001216 233.0
PYH2_k127_5860631_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000102 220.0
PYH2_k127_5860631_17 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000001828 209.0
PYH2_k127_5860631_18 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000002947 201.0
PYH2_k127_5860631_19 Putative phosphatase (DUF442) - - - 0.000000000000000000000000000000000000000105 154.0
PYH2_k127_5860631_2 56kDa selenium binding protein (SBP56) K17285 - - 2.858e-259 807.0
PYH2_k127_5860631_20 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000000008283 134.0
PYH2_k127_5860631_21 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000005642 101.0
PYH2_k127_5860631_3 TRAP dicarboxylate transporter, DctM subunit K03299 - - 1.439e-219 687.0
PYH2_k127_5860631_4 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.829e-201 657.0
PYH2_k127_5860631_5 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 582.0
PYH2_k127_5860631_6 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 582.0
PYH2_k127_5860631_7 fumarate reductase succinate dehydrogenase flavoprotein domain protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 579.0
PYH2_k127_5860631_8 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 536.0
PYH2_k127_5860631_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 531.0
PYH2_k127_58716_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 489.0
PYH2_k127_58716_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001712 275.0
PYH2_k127_58716_2 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001584 235.0
PYH2_k127_58716_3 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000006464 144.0
PYH2_k127_58716_4 RNA polymerase sigma factor, sigma-70 family - - - 0.000000000001815 71.0
PYH2_k127_58716_5 Histidine kinase - - - 0.0000000000657 67.0
PYH2_k127_5871868_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 8.591e-294 906.0
PYH2_k127_5871868_1 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 520.0
PYH2_k127_5871868_10 KR domain - - - 0.000000000000001453 82.0
PYH2_k127_5871868_11 Macro domain protein - - - 0.00000000000002488 79.0
PYH2_k127_5871868_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 469.0
PYH2_k127_5871868_3 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 454.0
PYH2_k127_5871868_4 SMART AAA ATPase K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 430.0
PYH2_k127_5871868_5 Belongs to the UPF0311 family - - - 0.0000000000000000000000000000000000000000000000000000000001428 227.0
PYH2_k127_5871868_6 Uncharacterised protein family (UPF0149) K07039 - - 0.000000000000000000000000000000000000000000000000000000001433 209.0
PYH2_k127_5871868_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000002294 199.0
PYH2_k127_5871868_8 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000007026 136.0
PYH2_k127_5871868_9 domain protein - - - 0.0000000000000000000005189 98.0
PYH2_k127_5873182_0 FAD linked oxidase domain protein - - - 0.0 1605.0
PYH2_k127_589035_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.436e-195 638.0
PYH2_k127_589035_1 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 610.0
PYH2_k127_589035_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 580.0
PYH2_k127_5901600_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001579 266.0
PYH2_k127_5901600_1 Nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001488 257.0
PYH2_k127_5901600_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000000000000000004883 209.0
PYH2_k127_5901600_3 AAA domain - - - 0.00000000000000000000000000000000000000000000000004469 183.0
PYH2_k127_5901600_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000008252 120.0
PYH2_k127_5901600_5 - - - - 0.000000000000000000007252 97.0
PYH2_k127_5904396_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 540.0
PYH2_k127_5904396_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 431.0
PYH2_k127_5904396_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 431.0
PYH2_k127_5904396_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 433.0
PYH2_k127_5904396_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 395.0
PYH2_k127_5904396_5 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 324.0
PYH2_k127_5904396_6 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 322.0
PYH2_k127_5904396_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 303.0
PYH2_k127_5904396_8 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000008982 75.0
PYH2_k127_5946886_0 von Willebrand factor, type A K07114 - - 7.499e-255 807.0
PYH2_k127_5946886_1 Extracellular ligand-binding receptor K01999 - - 7.963e-200 629.0
PYH2_k127_5946886_10 - - - - 0.000000000000001341 83.0
PYH2_k127_5946886_11 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0002758 45.0
PYH2_k127_5946886_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 492.0
PYH2_k127_5946886_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 483.0
PYH2_k127_5946886_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 452.0
PYH2_k127_5946886_5 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 417.0
PYH2_k127_5946886_6 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 385.0
PYH2_k127_5946886_7 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 363.0
PYH2_k127_5946886_8 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 335.0
PYH2_k127_5946886_9 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 293.0
PYH2_k127_5947467_0 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 475.0
PYH2_k127_5947467_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 445.0
PYH2_k127_5947467_2 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000102 109.0
PYH2_k127_5977153_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 487.0
PYH2_k127_5977153_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 398.0
PYH2_k127_5977153_2 Methyltransferase type 11 K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 310.0
PYH2_k127_5977153_3 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 304.0
PYH2_k127_5980304_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1152.0
PYH2_k127_5980304_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K13796 - - 2.599e-235 732.0
PYH2_k127_5980304_2 CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 561.0
PYH2_k127_5980304_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 482.0
PYH2_k127_5980304_4 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 422.0
PYH2_k127_5980304_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000001807 156.0
PYH2_k127_5983341_0 Carboxyl transferase domain K01969 - 6.4.1.4 9.439e-206 643.0
PYH2_k127_5983341_1 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 404.0
PYH2_k127_5983341_2 PFAM DinB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 258.0
PYH2_k127_5983341_3 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000009153 179.0
PYH2_k127_5983849_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 496.0
PYH2_k127_5983849_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000004418 224.0
PYH2_k127_5983849_2 Lysozyme inhibitor LprI - - - 0.0000000000000000000000000000000000000000000000000000000000173 223.0
PYH2_k127_5983849_3 - - - - 0.00000000000000000000000000000002022 142.0
PYH2_k127_5983849_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000008083 130.0
PYH2_k127_5983849_5 - - - - 0.00000000000000000000001561 106.0
PYH2_k127_5983849_6 - - - - 0.000000000000000001073 90.0
PYH2_k127_5984214_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2577.0
PYH2_k127_5984214_1 Guanine deaminase (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH) (GDEase) K01487 - 3.5.4.3 0.00000000000000000000000004683 110.0
PYH2_k127_5988065_0 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 317.0
PYH2_k127_5988065_1 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000001516 179.0
PYH2_k127_5988065_2 Las17-binding protein actin regulator - - - 0.000002443 50.0
PYH2_k127_5994696_0 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1306.0
PYH2_k127_5994696_1 fad dependent oxidoreductase K07137 - - 2.314e-284 882.0
PYH2_k127_5994696_2 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 8.831e-229 718.0
PYH2_k127_5994696_3 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 597.0
PYH2_k127_5994696_5 - - - - 0.0000000000000009286 83.0
PYH2_k127_5994696_6 Domain of unknown function (DUF4124) - - - 0.0000000299 62.0
PYH2_k127_6004809_0 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001097 244.0
PYH2_k127_6004809_1 protein import - - - 0.00000000000000000000000000000000000000000001124 171.0
PYH2_k127_6004809_2 SnoaL-like domain K06893 - - 0.00000000001071 69.0
PYH2_k127_6004809_3 Transcriptional regulator, LuxR family - - - 0.00000000004438 72.0
PYH2_k127_6004809_4 helix_turn_helix, Lux Regulon - - - 0.0000000003584 64.0
PYH2_k127_6004809_5 Transcriptional regulator K01719 - 4.2.1.75 0.0000001904 64.0
PYH2_k127_600573_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1045.0
PYH2_k127_600573_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 3.028e-213 666.0
PYH2_k127_600573_10 Coenzyme A transferase K01031 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 374.0
PYH2_k127_600573_11 PFAM Coenzyme A transferase K01032 - 2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 354.0
PYH2_k127_600573_12 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 347.0
PYH2_k127_600573_13 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 311.0
PYH2_k127_600573_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 293.0
PYH2_k127_600573_15 Protein of unknown function (DUF2726) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 281.0
PYH2_k127_600573_16 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006045 270.0
PYH2_k127_600573_17 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001422 246.0
PYH2_k127_600573_18 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004472 242.0
PYH2_k127_600573_19 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001702 250.0
PYH2_k127_600573_2 Transmembrane secretion effector - - - 3.411e-209 663.0
PYH2_k127_600573_20 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000003042 218.0
PYH2_k127_600573_21 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000007281 192.0
PYH2_k127_600573_22 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000001132 120.0
PYH2_k127_600573_3 PFAM extracellular solute-binding protein family 1 K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 596.0
PYH2_k127_600573_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 518.0
PYH2_k127_600573_5 L-2-hydroxyglutarate oxidase LhgO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 494.0
PYH2_k127_600573_6 PFAM FAD dependent oxidoreductase K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 490.0
PYH2_k127_600573_7 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 449.0
PYH2_k127_600573_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 436.0
PYH2_k127_600573_9 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 425.0
PYH2_k127_6033083_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 530.0
PYH2_k127_6033083_1 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000973 223.0
PYH2_k127_6033083_2 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000000000000000001223 212.0
PYH2_k127_6055122_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1011.0
PYH2_k127_6055122_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 9.054e-266 824.0
PYH2_k127_6055122_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 571.0
PYH2_k127_6066970_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 376.0
PYH2_k127_6066970_1 - - - - 0.000000001776 65.0
PYH2_k127_6066970_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01055 - 3.1.1.24 0.0000209 51.0
PYH2_k127_6071229_0 oxidoreductase K04090 - 1.2.7.8 0.0 1478.0
PYH2_k127_6071229_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 332.0
PYH2_k127_6084357_0 Lytic transglycosylase catalytic K08309 - - 4.468e-259 815.0
PYH2_k127_6084357_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.172e-250 779.0
PYH2_k127_6084357_2 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 496.0
PYH2_k127_6084357_3 LysR family K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 400.0
PYH2_k127_6084357_4 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 343.0
PYH2_k127_6084357_5 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 321.0
PYH2_k127_6084357_6 TfoX N-terminal domain K07343 - - 0.00000000000000000000000000000001559 134.0
PYH2_k127_6084357_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01322 - 3.4.21.26 0.000000000000000000000000147 117.0
PYH2_k127_6084357_8 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000001126 109.0
PYH2_k127_6084357_9 Protein of unknown function (DUF2917) - - - 0.0000000007877 64.0
PYH2_k127_6087245_0 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 500.0
PYH2_k127_6087245_1 PFAM Fibronectin type III domain protein K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 372.0
PYH2_k127_6087318_0 Proton-conducting membrane transporter K12141 - - 3.768e-278 860.0
PYH2_k127_6087318_1 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 520.0
PYH2_k127_6087318_2 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 346.0
PYH2_k127_6087318_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000001352 61.0
PYH2_k127_6088534_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 378.0
PYH2_k127_6088534_1 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002628 274.0
PYH2_k127_6088534_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002704 253.0
PYH2_k127_6088534_4 - - - - 0.00001864 51.0
PYH2_k127_61365_0 Domain of unknown function (DUF5117) - - - 5.543e-212 670.0
PYH2_k127_61365_1 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 563.0
PYH2_k127_61365_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000062 176.0
PYH2_k127_61365_3 - - - - 0.0000000000000000000000000000000000000000001644 167.0
PYH2_k127_6173020_0 Sulfatase K01130 - 3.1.6.1 4.763e-297 917.0
PYH2_k127_6173020_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 535.0
PYH2_k127_6173020_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000001088 231.0
PYH2_k127_6173020_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000005495 182.0
PYH2_k127_6173020_4 Putative transposase - - - 0.00005495 48.0
PYH2_k127_6267838_0 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008418 269.0
PYH2_k127_6267838_1 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000002431 239.0
PYH2_k127_6267838_2 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000002037 100.0
PYH2_k127_6276960_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.916e-208 658.0
PYH2_k127_6276960_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 3.516e-207 653.0
PYH2_k127_6276960_10 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000000000000006177 153.0
PYH2_k127_6276960_11 Protein of unknown function (DUF3579) - - - 0.000000000000000000000000002244 117.0
PYH2_k127_6276960_2 acetylornithine K00821 - 2.6.1.11,2.6.1.17 1.114e-206 654.0
PYH2_k127_6276960_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 578.0
PYH2_k127_6276960_4 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 538.0
PYH2_k127_6276960_5 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 497.0
PYH2_k127_6276960_6 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 370.0
PYH2_k127_6276960_7 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 323.0
PYH2_k127_6276960_8 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000001607 192.0
PYH2_k127_6276960_9 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000006167 166.0
PYH2_k127_629568_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 464.0
PYH2_k127_629568_1 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000002821 251.0
PYH2_k127_6314408_0 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 1.962e-317 986.0
PYH2_k127_6314408_1 Winged helix-turn helix - - - 1.911e-196 614.0
PYH2_k127_6314408_2 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 346.0
PYH2_k127_6314408_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 336.0
PYH2_k127_6314408_4 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 286.0
PYH2_k127_6314408_5 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 290.0
PYH2_k127_6314408_6 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000001258 220.0
PYH2_k127_6314408_7 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000001574 122.0
PYH2_k127_6314408_8 Belongs to the UPF0061 (SELO) family - - - 0.000000000000000000000003959 115.0
PYH2_k127_6314408_9 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000002836 106.0
PYH2_k127_6320692_0 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-17-dioic acid hydratase (catechol pathway) K18336 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 489.0
PYH2_k127_6320692_1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases K18335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 301.0
PYH2_k127_6320692_2 D-galactarate dehydratase Altronate hydrolase K01685,K16846 - 4.2.1.7,4.4.1.24 0.00000000000000000000000000000000000000003049 156.0
PYH2_k127_6351967_0 PFAM NnrS family protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 549.0
PYH2_k127_6351967_1 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 351.0
PYH2_k127_6351967_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001256 248.0
PYH2_k127_6351967_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04109,K11178 - 1.17.1.4,1.3.7.9 0.00000000000000000000000000000000000000000000000003556 183.0
PYH2_k127_6351967_4 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000003967 127.0
PYH2_k127_6351967_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000001364 93.0
PYH2_k127_6351967_6 TonB dependent receptor K02014 - - 0.00000000000001812 74.0
PYH2_k127_6352342_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.75e-269 833.0
PYH2_k127_6352342_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.375e-260 815.0
PYH2_k127_6352342_2 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 1.245e-238 742.0
PYH2_k127_6352342_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 331.0
PYH2_k127_6352342_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 322.0
PYH2_k127_6352342_5 NADH dehydrogenase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002236 252.0
PYH2_k127_6352342_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000007527 226.0
PYH2_k127_637399_0 AMP-binding enzyme - - - 1.585e-278 865.0
PYH2_k127_637399_1 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000251 282.0
PYH2_k127_637399_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K07678 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000206 269.0
PYH2_k127_637399_3 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000307 237.0
PYH2_k127_637399_4 ABC transporter substrate binding protein - - - 0.0000000000000000000000000001473 119.0
PYH2_k127_637399_5 to nucleic acid-binding protein contains PIN domain - - - 0.0000000000000000136 84.0
PYH2_k127_637399_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000009766 72.0
PYH2_k127_637399_7 ABC transporter substrate binding protein K01989 - - 0.000000008634 58.0
PYH2_k127_637399_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000532 49.0
PYH2_k127_6422979_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1046.0
PYH2_k127_6422979_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.301e-247 772.0
PYH2_k127_6422979_10 Protein of unknown function (DUF805) - - - 0.00000000000000000000000000001494 132.0
PYH2_k127_6422979_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 9.564e-209 660.0
PYH2_k127_6422979_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 590.0
PYH2_k127_6422979_4 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 508.0
PYH2_k127_6422979_5 Endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 395.0
PYH2_k127_6422979_6 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 351.0
PYH2_k127_6422979_7 Nudix hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000000000000000008361 252.0
PYH2_k127_6422979_8 Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) K00520,K21739 - 1.16.1.1 0.000000000000000000000000000000000000007935 146.0
PYH2_k127_6422979_9 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000000003686 136.0
PYH2_k127_643891_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 1.698e-275 856.0
PYH2_k127_643891_1 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 566.0
PYH2_k127_643891_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 545.0
PYH2_k127_643891_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 320.0
PYH2_k127_643891_4 Protein of unknown function (DUF3175) - - - 0.0000000000000000000001396 98.0
PYH2_k127_643891_5 Protein of unknown function (DUF2783) - - - 0.000000000000000003324 87.0
PYH2_k127_6483801_0 e3 binding domain K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 432.0
PYH2_k127_6483801_1 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 379.0
PYH2_k127_6483801_2 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.0000000000000000000000000000000000000000000000000000000000000000000000287 246.0
PYH2_k127_6483801_3 Type II secretion system protein B K02451 - - 0.0000000000000000000000003258 108.0
PYH2_k127_6484755_0 Adenylate - - - 1.426e-230 758.0
PYH2_k127_6484755_1 Adenylate cyclase K01768 - 4.6.1.1 7.563e-228 728.0
PYH2_k127_6484755_2 Histidine kinase K07711 - 2.7.13.3 2.123e-222 699.0
PYH2_k127_6484755_3 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 518.0
PYH2_k127_6484755_4 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000000000000000000001865 183.0
PYH2_k127_6518706_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 9.111e-256 802.0
PYH2_k127_6518706_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 430.0
PYH2_k127_6518706_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 347.0
PYH2_k127_6518706_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 316.0
PYH2_k127_6518706_4 Flavodoxin-like fold K00355,K11746,K11748 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 287.0
PYH2_k127_6518706_5 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000000000000000000001968 224.0
PYH2_k127_6518706_6 Protein of unknown function (DUF2652) - - - 0.0000000000000000000000000000000000000000000000000000000000000002976 244.0
PYH2_k127_6518706_7 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000001897 228.0
PYH2_k127_6518706_8 Histidine kinase - - - 0.00000000000000149 88.0
PYH2_k127_6527998_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1190.0
PYH2_k127_6527998_1 Insulinase (Peptidase family M16) K07263 - - 0.0 1169.0
PYH2_k127_6527998_10 RDD family - - - 0.000000000000000000000000000000000000000000000000000000001883 206.0
PYH2_k127_6527998_11 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000001646 181.0
PYH2_k127_6527998_12 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000005221 173.0
PYH2_k127_6527998_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000006228 100.0
PYH2_k127_6527998_14 Protein of unknown function (DUF3106) - - - 0.0001071 44.0
PYH2_k127_6527998_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 6.226e-275 854.0
PYH2_k127_6527998_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 537.0
PYH2_k127_6527998_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008177 438.0
PYH2_k127_6527998_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 327.0
PYH2_k127_6527998_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 328.0
PYH2_k127_6527998_7 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000007865 244.0
PYH2_k127_6527998_8 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000009427 243.0
PYH2_k127_6527998_9 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000002334 208.0
PYH2_k127_6543241_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 0.0 1154.0
PYH2_k127_6543241_1 Acetyl-CoA dehydrogenase C-terminal like K00248 - 1.3.8.1 2.117e-315 973.0
PYH2_k127_6543241_10 Thioesterase superfamily - - - 0.000000000000000000000000000000000009835 140.0
PYH2_k127_6543241_11 KR domain K00046 - 1.1.1.69 0.0000000000000000000000001865 107.0
PYH2_k127_6543241_2 peptidase dimerisation domain protein K13049 - - 5.174e-228 715.0
PYH2_k127_6543241_3 Belongs to the thiolase family K00626 - 2.3.1.9 1.999e-216 676.0
PYH2_k127_6543241_4 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 479.0
PYH2_k127_6543241_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 484.0
PYH2_k127_6543241_6 Alpha beta hydrolase K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 381.0
PYH2_k127_6543241_7 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 371.0
PYH2_k127_6543241_8 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 376.0
PYH2_k127_6543241_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002174 263.0
PYH2_k127_6543507_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 334.0
PYH2_k127_6545646_0 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 602.0
PYH2_k127_6545646_1 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 473.0
PYH2_k127_6545646_10 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000004535 74.0
PYH2_k127_6545646_11 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000001731 55.0
PYH2_k127_6545646_2 LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 436.0
PYH2_k127_6545646_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 435.0
PYH2_k127_6545646_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 348.0
PYH2_k127_6545646_5 Pyridoxamine 5'-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 343.0
PYH2_k127_6545646_6 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 339.0
PYH2_k127_6545646_7 PFAM transposase, mutator K07493 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005737 289.0
PYH2_k127_6545646_8 HicB family - - - 0.000000000000000000000000000000000000000000000000002803 183.0
PYH2_k127_6545646_9 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000003563 121.0
PYH2_k127_6596506_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 4.886e-230 719.0
PYH2_k127_6596506_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.339e-211 669.0
PYH2_k127_6596506_2 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 570.0
PYH2_k127_6596506_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 461.0
PYH2_k127_6596506_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000117 194.0
PYH2_k127_6596506_5 - - - - 0.000002524 60.0
PYH2_k127_6616431_0 TOBE domain K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 575.0
PYH2_k127_6616431_1 Regulatory protein GntR HTH K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 317.0
PYH2_k127_6616431_2 ABC-type sugar transport system, periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 304.0
PYH2_k127_6617005_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 428.0
PYH2_k127_6617005_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 430.0
PYH2_k127_6617005_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 371.0
PYH2_k127_6617005_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 294.0
PYH2_k127_6624250_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0 1084.0
PYH2_k127_6624250_1 Fis family transcriptional regulator - - - 1.316e-282 878.0
PYH2_k127_6624250_10 Cold shock protein K03704 - - 0.0000000000000000000000000000006968 123.0
PYH2_k127_6624250_11 oxidoreductase K04090 - 1.2.7.8 0.0000000000000000000000000001643 118.0
PYH2_k127_6624250_12 GYD domain - - - 0.000000000000000000000004146 106.0
PYH2_k127_6624250_13 Flavin reductase like domain - - - 0.000000001354 68.0
PYH2_k127_6624250_14 - - - - 0.0000001155 56.0
PYH2_k127_6624250_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 3.236e-281 881.0
PYH2_k127_6624250_3 Peptidase family M48 - - - 3.901e-214 677.0
PYH2_k127_6624250_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 562.0
PYH2_k127_6624250_5 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 284.0
PYH2_k127_6624250_6 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000123 298.0
PYH2_k127_6624250_7 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.0000000000000000000000000000000000000000000000000000002051 203.0
PYH2_k127_6624250_8 cyclic nucleotide binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000003283 199.0
PYH2_k127_6624250_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000001288 139.0
PYH2_k127_663369_0 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 2.633e-250 783.0
PYH2_k127_663369_1 Short-chain dehydrogenase reductase sdr - - - 8.575e-232 723.0
PYH2_k127_663369_10 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000002142 163.0
PYH2_k127_663369_11 Belongs to the ompA family - - - 0.00000000000000000000000000000000000007731 147.0
PYH2_k127_663369_12 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000005964 129.0
PYH2_k127_663369_13 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000008909 126.0
PYH2_k127_663369_14 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000005839 95.0
PYH2_k127_663369_15 Permeases of the drug metabolite transporter - - - 0.0000006713 56.0
PYH2_k127_663369_16 prlF antitoxin for toxin YhaV_toxin - - - 0.00003588 48.0
PYH2_k127_663369_2 Methionine synthase K00549 - 2.1.1.14 1.051e-201 631.0
PYH2_k127_663369_3 acetyl-coa acetyltransferase - - - 1.256e-199 649.0
PYH2_k127_663369_4 PFAM cyclase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 495.0
PYH2_k127_663369_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 400.0
PYH2_k127_663369_6 Diguanylate cyclase K20956,K21021 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032153,GO:0032879,GO:0033554,GO:0036460,GO:0040012,GO:0040013,GO:0042802,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0051271,GO:0051716,GO:0052621,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 308.0
PYH2_k127_663369_7 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003366 256.0
PYH2_k127_663369_8 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005922 234.0
PYH2_k127_663369_9 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003947 244.0
PYH2_k127_663990_0 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 540.0
PYH2_k127_663990_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 433.0
PYH2_k127_663990_2 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000000001123 138.0
PYH2_k127_663990_3 FAD linked oxidases, C-terminal domain - - - 0.0000000001776 68.0
PYH2_k127_6640066_0 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 419.0
PYH2_k127_6640066_1 D-isomer specific 2-hydroxyacid dehydrogenase K00090 - 1.1.1.215,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 387.0
PYH2_k127_6640629_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1021.0
PYH2_k127_6640629_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.356e-241 761.0
PYH2_k127_6640629_10 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 373.0
PYH2_k127_6640629_11 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 347.0
PYH2_k127_6640629_12 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 340.0
PYH2_k127_6640629_13 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 293.0
PYH2_k127_6640629_14 Rod shape-determining protein mreD K03571 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003219 271.0
PYH2_k127_6640629_15 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007754 272.0
PYH2_k127_6640629_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000001584 239.0
PYH2_k127_6640629_17 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000004015 144.0
PYH2_k127_6640629_18 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000004931 141.0
PYH2_k127_6640629_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 1.531e-215 671.0
PYH2_k127_6640629_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.862e-199 631.0
PYH2_k127_6640629_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 1.176e-198 623.0
PYH2_k127_6640629_5 two-component sensor kinase K07649 - 2.7.13.3 3.984e-197 626.0
PYH2_k127_6640629_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 2.634e-195 617.0
PYH2_k127_6640629_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 544.0
PYH2_k127_6640629_8 PFAM response regulator receiver K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 400.0
PYH2_k127_6640629_9 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 422.0
PYH2_k127_667152_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 493.0
PYH2_k127_667152_1 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000000004051 237.0
PYH2_k127_667152_2 transport system periplasmic component - - - 0.000000000000000000000000000000000000000003923 160.0
PYH2_k127_667152_3 4-vinyl reductase, 4VR K07013,K17763 - - 0.00000000000000000000000000000000009071 144.0
PYH2_k127_6674432_0 Tetratricopeptide repeat - - - 7.366e-261 817.0
PYH2_k127_6674432_1 Tetratricopeptide repeat - - - 1.619e-245 770.0
PYH2_k127_6674432_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 294.0
PYH2_k127_6680491_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 388.0
PYH2_k127_6680491_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 359.0
PYH2_k127_6680491_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 356.0
PYH2_k127_6680491_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 314.0
PYH2_k127_6680491_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 315.0
PYH2_k127_6680491_5 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016,K06858 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006174 285.0
PYH2_k127_6680491_6 (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 272.0
PYH2_k127_6680491_7 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000007768 86.0
PYH2_k127_6696505_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.237e-259 812.0
PYH2_k127_6696505_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 565.0
PYH2_k127_6696505_2 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 418.0
PYH2_k127_6696505_3 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000006056 249.0
PYH2_k127_6696505_4 Protein of unknown function (DUF1499) - - - 0.000000003931 61.0
PYH2_k127_6710803_0 GMC family oxidoreductase - - - 2.344e-247 777.0
PYH2_k127_6710803_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 2.828e-212 662.0
PYH2_k127_6710803_2 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 349.0
PYH2_k127_6710803_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002514 260.0
PYH2_k127_6710803_4 - - - - 0.000000000000000000000000000000000000000000005062 169.0
PYH2_k127_6710803_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000001394 62.0
PYH2_k127_6743659_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 610.0
PYH2_k127_6743659_1 Ion transport 2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 603.0
PYH2_k127_6743659_10 mRNA catabolic process K06950 - - 0.0000000000000000000000000000000235 132.0
PYH2_k127_6743659_11 von Willebrand factor type A K07114 - - 0.000000000000000000000000000002726 125.0
PYH2_k127_6743659_12 ABC transporter substrate binding protein K01989 - - 0.00000000125 64.0
PYH2_k127_6743659_2 Sodium:sulfate symporter transmembrane region K03319,K09477,K11106,K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 589.0
PYH2_k127_6743659_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 437.0
PYH2_k127_6743659_4 Strictosidine synthase K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 320.0
PYH2_k127_6743659_5 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 321.0
PYH2_k127_6743659_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004182 222.0
PYH2_k127_6743659_7 Strictosidine synthase K10440 - - 0.00000000000000000000000000000000000000000000000000000000000002417 220.0
PYH2_k127_6743659_8 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000006681 195.0
PYH2_k127_6743659_9 MAPEG family - - - 0.0000000000000000000000000000000000000000000007775 169.0
PYH2_k127_6760725_0 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009728 602.0
PYH2_k127_6760725_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 419.0
PYH2_k127_6760725_2 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 368.0
PYH2_k127_6760725_3 ferredoxin - - - 0.000000000000000000000000000000000002496 145.0
PYH2_k127_6760725_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000007348 144.0
PYH2_k127_6760725_5 PFAM Peptidase M23 - - - 0.00000000000000000000000008787 109.0
PYH2_k127_6765256_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 8.219e-260 811.0
PYH2_k127_6765256_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 3.443e-226 718.0
PYH2_k127_6765256_10 D-galactarate dehydratase Altronate hydrolase K01708,K16846 - 4.2.1.42,4.4.1.24 0.00000003565 57.0
PYH2_k127_6765256_2 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 518.0
PYH2_k127_6765256_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 415.0
PYH2_k127_6765256_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 396.0
PYH2_k127_6765256_5 SBF-like CPA transporter family (DUF4137) K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 375.0
PYH2_k127_6765256_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000002229 215.0
PYH2_k127_6765256_7 Adenylate - - - 0.00000000000000000000000000000000000000000000000000000000004145 211.0
PYH2_k127_6765256_8 FCD - - - 0.0000000000000000000000000000000000000000000000000212 184.0
PYH2_k127_6765256_9 Outer membrane protein beta-barrel domain - - - 0.00000001674 64.0
PYH2_k127_6795902_0 Benzoate-CoA ligase family K04110 - 6.2.1.25 1.365e-269 844.0
PYH2_k127_6795902_1 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 566.0
PYH2_k127_6795902_10 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 371.0
PYH2_k127_6795902_11 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 295.0
PYH2_k127_6795902_12 carbonic anhydrase K01674 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000005271 241.0
PYH2_k127_6795902_13 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000000000000001576 229.0
PYH2_k127_6795902_14 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000002651 185.0
PYH2_k127_6795902_15 amine dehydrogenase activity K13730 - - 0.0000000000000000000000000000008022 136.0
PYH2_k127_6795902_16 Rubrerythrin - - - 0.000000000000000000000000000005549 136.0
PYH2_k127_6795902_17 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000003016 86.0
PYH2_k127_6795902_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 474.0
PYH2_k127_6795902_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 450.0
PYH2_k127_6795902_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 448.0
PYH2_k127_6795902_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 421.0
PYH2_k127_6795902_6 Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 415.0
PYH2_k127_6795902_7 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 401.0
PYH2_k127_6795902_8 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 388.0
PYH2_k127_6795902_9 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 370.0
PYH2_k127_6801554_0 Bacterial extracellular solute-binding protein K17315 - - 4.46e-220 687.0
PYH2_k127_6801554_1 basic membrane K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 611.0
PYH2_k127_6801554_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 537.0
PYH2_k127_6801554_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 503.0
PYH2_k127_6801554_4 Binding-protein-dependent transport system inner membrane component K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 500.0
PYH2_k127_6801554_5 Binding-protein-dependent transport system inner membrane component K17317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 492.0
PYH2_k127_6801554_6 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 403.0
PYH2_k127_6801554_7 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 293.0
PYH2_k127_6801554_8 ABC transporter K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000064 276.0
PYH2_k127_6801672_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.4e-323 992.0
PYH2_k127_6801672_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 466.0
PYH2_k127_6801672_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 329.0
PYH2_k127_6801672_3 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000007896 161.0
PYH2_k127_6844015_0 Phosphate acetyl butaryl transferase K00029 - 1.1.1.40 0.0 1212.0
PYH2_k127_6844015_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.046e-271 857.0
PYH2_k127_6844015_10 enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 372.0
PYH2_k127_6844015_11 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 369.0
PYH2_k127_6844015_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 361.0
PYH2_k127_6844015_13 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 349.0
PYH2_k127_6844015_14 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 342.0
PYH2_k127_6844015_15 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 329.0
PYH2_k127_6844015_16 Barstar (barnase inhibitor) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001634 243.0
PYH2_k127_6844015_17 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000002768 219.0
PYH2_k127_6844015_18 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000004234 179.0
PYH2_k127_6844015_19 Ribonuclease K01167 - 3.1.27.3 0.0000000000000000000000000000000000000000002564 167.0
PYH2_k127_6844015_2 Peptidase dimerisation domain - - - 1.067e-250 781.0
PYH2_k127_6844015_3 Amidohydrolase family K01485 - 3.5.4.1 2.868e-226 713.0
PYH2_k127_6844015_4 Flavin-binding monooxygenase-like - - - 9.173e-213 685.0
PYH2_k127_6844015_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.043e-204 644.0
PYH2_k127_6844015_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 502.0
PYH2_k127_6844015_7 Phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 479.0
PYH2_k127_6844015_8 Protein of unknown function (DUF1688) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 460.0
PYH2_k127_6844015_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 426.0
PYH2_k127_687437_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 512.0
PYH2_k127_687437_1 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 466.0
PYH2_k127_687437_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000001653 77.0
PYH2_k127_6964218_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 3.962e-239 755.0
PYH2_k127_6964218_1 PFAM TrkA-N domain protein K03499 - - 6.374e-225 704.0
PYH2_k127_6964218_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000003937 214.0
PYH2_k127_698138_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 3.812e-320 986.0
PYH2_k127_698138_1 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 1.111e-238 740.0
PYH2_k127_698138_2 Belongs to the thiolase family K00626 - 2.3.1.9 1.092e-209 656.0
PYH2_k127_698138_3 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 410.0
PYH2_k127_698138_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 361.0
PYH2_k127_698138_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 251.0
PYH2_k127_698138_6 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000002823 194.0
PYH2_k127_698138_7 Lysine exporter protein LysE K11250 - - 0.0003759 49.0
PYH2_k127_7011329_0 histidine kinase, dimerisation and phosphoacceptor region K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 505.0
PYH2_k127_7011329_1 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 366.0
PYH2_k127_7011329_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000001121 196.0
PYH2_k127_7011329_3 diguanylate cyclase activity K21021 - 2.7.7.65 0.000000000000000000000000000000000000000000000000004191 185.0
PYH2_k127_7011329_4 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000005847 181.0
PYH2_k127_7011329_5 cell septum assembly - - - 0.0000000000000000000000000000001141 126.0
PYH2_k127_7011329_6 Protein of unknown function (DUF1328) - - - 0.00000000000001364 78.0
PYH2_k127_7039022_0 Circularly permuted ATP-grasp type 2 - - - 2.912e-276 853.0
PYH2_k127_7039022_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 541.0
PYH2_k127_7039022_2 Lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 428.0
PYH2_k127_7039022_3 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004066 254.0
PYH2_k127_7057366_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.224e-203 636.0
PYH2_k127_7057366_1 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 515.0
PYH2_k127_7057366_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000005439 224.0
PYH2_k127_7057613_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256 - 1.3.99.16 2.895e-310 974.0
PYH2_k127_7057613_1 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 1.377e-262 816.0
PYH2_k127_7057613_2 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 526.0
PYH2_k127_7057613_3 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 372.0
PYH2_k127_7057613_4 Drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 262.0
PYH2_k127_7057613_5 2Fe-2S -binding domain protein K18029 - 1.17.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000108 243.0
PYH2_k127_7057613_6 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003488 245.0
PYH2_k127_7057613_7 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000634 225.0
PYH2_k127_7057613_8 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000531 199.0
PYH2_k127_7057613_9 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000001737 187.0
PYH2_k127_7078382_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1590.0
PYH2_k127_7078382_1 RNB K01147 - 3.1.13.1 3.497e-320 992.0
PYH2_k127_7078382_10 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 4.218e-220 686.0
PYH2_k127_7078382_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 610.0
PYH2_k127_7078382_12 ABC-type dipeptide oligopeptide nickel transport K12369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 602.0
PYH2_k127_7078382_13 PFAM ATP-binding region, ATPase domain protein K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 587.0
PYH2_k127_7078382_14 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 528.0
PYH2_k127_7078382_15 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 505.0
PYH2_k127_7078382_16 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 461.0
PYH2_k127_7078382_17 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 458.0
PYH2_k127_7078382_18 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 458.0
PYH2_k127_7078382_19 ABC-type dipeptide oligopeptide nickel transport system, permease component K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 453.0
PYH2_k127_7078382_2 Type IV pili methyl-accepting chemotaxis transducer N-term K02660 - - 7.213e-301 941.0
PYH2_k127_7078382_20 Belongs to the ABC transporter superfamily K12372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 452.0
PYH2_k127_7078382_21 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 452.0
PYH2_k127_7078382_22 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 400.0
PYH2_k127_7078382_23 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 393.0
PYH2_k127_7078382_24 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 358.0
PYH2_k127_7078382_25 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 357.0
PYH2_k127_7078382_26 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 351.0
PYH2_k127_7078382_27 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 332.0
PYH2_k127_7078382_28 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 304.0
PYH2_k127_7078382_29 Negative regulator of K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000575 271.0
PYH2_k127_7078382_3 ABC-type dipeptide transport system, periplasmic component K02035,K12368 - - 5.346e-295 912.0
PYH2_k127_7078382_30 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001616 270.0
PYH2_k127_7078382_31 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000001858 241.0
PYH2_k127_7078382_32 response regulator, receiver K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000000004225 233.0
PYH2_k127_7078382_33 TIGRFAM MJ0042 family finger-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000181 240.0
PYH2_k127_7078382_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000004922 222.0
PYH2_k127_7078382_35 PFAM response regulator receiver K02658 - - 0.0000000000000000000000000000000000000000000000000000000000005071 212.0
PYH2_k127_7078382_36 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000005501 210.0
PYH2_k127_7078382_37 PFAM CheW domain protein K02659 - - 0.0000000000000000000000000000000000000000000000000000000353 201.0
PYH2_k127_7078382_38 Protein of unknown function (DUF2726) - - - 0.00000000000000000000000000000000000000000000000002472 187.0
PYH2_k127_7078382_39 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000002355 162.0
PYH2_k127_7078382_4 ATP-binding region, ATPase domain protein K02487,K06596 - - 8.548e-291 916.0
PYH2_k127_7078382_40 - - - - 0.0000000000000000000000000000000000000003846 153.0
PYH2_k127_7078382_41 rubredoxin - - - 0.0000000000000000000000000000002492 122.0
PYH2_k127_7078382_42 - - - - 0.0000000000000000000001913 99.0
PYH2_k127_7078382_43 - K11275 - - 0.00000000000000000001232 95.0
PYH2_k127_7078382_44 - K06950 - - 0.000000006287 63.0
PYH2_k127_7078382_5 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 6.633e-269 831.0
PYH2_k127_7078382_6 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.148e-235 746.0
PYH2_k127_7078382_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.394e-231 724.0
PYH2_k127_7078382_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.614e-230 719.0
PYH2_k127_7078382_9 Aminotransferase K01845 - 5.4.3.8 6.858e-223 698.0
PYH2_k127_712138_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.706e-206 649.0
PYH2_k127_712138_1 Amidase K02433,K21801 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 441.0
PYH2_k127_712138_2 DinB family - - - 0.0000000000000000000000000000000000000000000000003313 181.0
PYH2_k127_712138_3 Rhodanese-like domain - - - 0.000000000000000000000000000000000000000000000001044 191.0
PYH2_k127_7194992_0 2Fe-2S iron-sulfur cluster binding domain K22086 - 1.5.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 451.0
PYH2_k127_7194992_1 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 447.0
PYH2_k127_7194992_2 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002137 271.0
PYH2_k127_7194992_3 Sarcosine oxidase, gamma subunit K00305 - 1.5.3.1 0.00000000000000000000402 101.0
PYH2_k127_7196237_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 570.0
PYH2_k127_7196237_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520,K04108 - 1.2.5.3,1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 477.0
PYH2_k127_7196237_2 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000001091 242.0
PYH2_k127_7196237_3 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000001002 54.0
PYH2_k127_7204232_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 565.0
PYH2_k127_7204232_1 Isocitrate lyase and phosphorylmutase K01841 - 5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 460.0
PYH2_k127_7204232_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 344.0
PYH2_k127_7204232_3 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004331 280.0
PYH2_k127_7204232_4 Transposase K07494 - - 0.00000000000000000000000003239 111.0
PYH2_k127_7204232_5 Putative regulatory protein - - - 0.000000000000000004842 93.0
PYH2_k127_7204232_6 FAD binding domain K00244 - 1.3.5.4 0.000000003721 57.0
PYH2_k127_7208731_0 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 409.0
PYH2_k127_7208731_1 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000001345 237.0
PYH2_k127_7212323_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.981e-286 887.0
PYH2_k127_7212323_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.975e-267 828.0
PYH2_k127_7212323_2 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 599.0
PYH2_k127_7212323_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002293 252.0
PYH2_k127_7212323_4 cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
PYH2_k127_7212323_5 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000003395 160.0
PYH2_k127_7212323_6 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000006296 138.0
PYH2_k127_7212323_7 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000002 76.0
PYH2_k127_7252675_0 ABC-type transport system, ATPase component K01995,K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 290.0
PYH2_k127_7252675_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002015 265.0
PYH2_k127_7257076_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 351.0
PYH2_k127_7257076_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 313.0
PYH2_k127_7257076_2 Transcriptional regulator - - - 0.00000000000000000000000000000002038 138.0
PYH2_k127_7257076_3 EamA-like transporter family - - - 0.000000000000000000000000003996 114.0
PYH2_k127_7257076_4 ABC transporter K15738 - - 0.000000000000000000001102 96.0
PYH2_k127_7284945_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1675.0
PYH2_k127_7284945_1 Biotin-lipoyl like - - - 0.000001225 51.0
PYH2_k127_7284945_2 Ion transport 2 domain protein K10716 - - 0.00002281 51.0
PYH2_k127_7296930_0 NADPH-dependent glutamate synthase beta - - - 0.0 1132.0
PYH2_k127_7296930_1 Fe-S oxidoreductase K21834 - - 5.517e-281 868.0
PYH2_k127_7296930_10 - - - - 0.0000000000000000000000000000000000000002095 156.0
PYH2_k127_7296930_11 DsrH like protein K07237 - - 0.000000000000000000000000000000004007 130.0
PYH2_k127_7296930_2 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 556.0
PYH2_k127_7296930_3 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 392.0
PYH2_k127_7296930_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 398.0
PYH2_k127_7296930_5 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 373.0
PYH2_k127_7296930_6 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 321.0
PYH2_k127_7296930_7 sulfur relay protein TusD DsrE K07235 - - 0.00000000000000000000000000000000000000000000000000000000000001702 216.0
PYH2_k127_7296930_8 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000557 208.0
PYH2_k127_7296930_9 Sulfur relay protein TusC DsrF K07236 - - 0.0000000000000000000000000000000000000000000000000000001213 196.0
PYH2_k127_7307610_0 Carboxyl transferase domain K01969 - 6.4.1.4 1.902e-258 803.0
PYH2_k127_7307610_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000004903 80.0
PYH2_k127_7310464_0 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 6.648e-247 775.0
PYH2_k127_7310464_1 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 603.0
PYH2_k127_7310464_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 466.0
PYH2_k127_7310464_3 - - - - 0.00000000000000001548 85.0
PYH2_k127_7331770_0 peptidase S45, penicillin amidase K01434 - 3.5.1.11 2.911e-320 994.0
PYH2_k127_7331770_1 Aminotransferase class-III K00819 - 2.6.1.13 7.795e-198 623.0
PYH2_k127_7331770_2 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 524.0
PYH2_k127_7331770_3 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 411.0
PYH2_k127_7331770_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 395.0
PYH2_k127_7331770_5 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 414.0
PYH2_k127_7331770_6 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 387.0
PYH2_k127_7331770_7 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000005692 211.0
PYH2_k127_7331770_8 alcohol dehydrogenase K00043,K13954 - 1.1.1.1,1.1.1.61 0.000000000000000000000003268 110.0
PYH2_k127_7341985_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000001112 238.0
PYH2_k127_7341985_1 NADH dehydrogenase K03885 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0036094,GO:0042592,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044464,GO:0045333,GO:0048037,GO:0048878,GO:0050136,GO:0050660,GO:0050662,GO:0050801,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:0098771,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000007331 220.0
PYH2_k127_7341985_2 Glycine zipper 2TM domain K04062 - - 0.00000000000000000001196 98.0
PYH2_k127_7388424_0 A predicted alpha-helical domain with a conserved ER motif. - - - 9.084e-304 946.0
PYH2_k127_7389966_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1463.0
PYH2_k127_7389966_1 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 445.0
PYH2_k127_7389966_2 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008504 424.0
PYH2_k127_7389966_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 399.0
PYH2_k127_7389966_4 - - - - 0.000000000000000000000000000000000000000007773 162.0
PYH2_k127_739230_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 505.0
PYH2_k127_739230_1 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 465.0
PYH2_k127_739230_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 374.0
PYH2_k127_739230_3 Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 352.0
PYH2_k127_739230_4 PFAM Asparaginase glutaminase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 340.0
PYH2_k127_739230_5 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000001526 194.0
PYH2_k127_739230_6 Pathogenicity locus K07343 - - 0.0000000000000000000000000000007205 123.0
PYH2_k127_739230_7 ABC transporter K06158 - - 0.0000000000000000002098 89.0
PYH2_k127_7398630_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 415.0
PYH2_k127_7398630_1 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 392.0
PYH2_k127_7398630_2 transferase activity, transferring acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001924 269.0
PYH2_k127_7398630_3 lipoprotein transporter activity K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000007627 229.0
PYH2_k127_7398630_4 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000001834 173.0
PYH2_k127_7407936_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 539.0
PYH2_k127_7407936_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 362.0
PYH2_k127_7407936_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 365.0
PYH2_k127_7407936_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003825 253.0
PYH2_k127_7407936_4 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000006281 166.0
PYH2_k127_7407936_5 - - - - 0.00000000000000000000000000000000000115 149.0
PYH2_k127_7418784_0 Protein of unknown function (DUF3141) - - - 0.0 1060.0
PYH2_k127_7418784_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 555.0
PYH2_k127_7418784_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000005002 124.0
PYH2_k127_7418784_11 PIN domain - - - 0.0000000000003406 78.0
PYH2_k127_7418784_12 Protein of unknown function (DUF2490) - - - 0.00000000001058 75.0
PYH2_k127_7418784_2 phosphate K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 518.0
PYH2_k127_7418784_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 445.0
PYH2_k127_7418784_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 396.0
PYH2_k127_7418784_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 371.0
PYH2_k127_7418784_6 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 337.0
PYH2_k127_7418784_7 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 337.0
PYH2_k127_7418784_8 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 331.0
PYH2_k127_7418784_9 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000003595 176.0
PYH2_k127_7427921_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 5.35e-303 932.0
PYH2_k127_7427921_1 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000624 272.0
PYH2_k127_7427921_2 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) - - - 0.00000000000000000000000000000003234 126.0
PYH2_k127_7427921_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.000000000002582 71.0
PYH2_k127_7483661_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 3.099e-258 804.0
PYH2_k127_7483661_1 Phosphoribosyltransferase K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 501.0
PYH2_k127_7483661_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002831 262.0
PYH2_k127_7483661_3 PFAM OsmC family protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000009566 233.0
PYH2_k127_7483661_4 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000005932 169.0
PYH2_k127_7501079_0 Spermidine putrescine-binding periplasmic protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 606.0
PYH2_k127_7501079_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 464.0
PYH2_k127_7501079_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 396.0
PYH2_k127_7501079_3 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 324.0
PYH2_k127_7501079_4 CHRD domain - - - 0.000000653 53.0
PYH2_k127_7501079_5 protein conserved in bacteria K05375 - - 0.000001383 55.0
PYH2_k127_7501079_6 nuclease K01174 - 3.1.31.1 0.00007344 45.0
PYH2_k127_7502028_0 PFAM 2-nitropropane dioxygenase NPD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 488.0
PYH2_k127_7502028_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 345.0
PYH2_k127_7502028_2 pfam abc1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 345.0
PYH2_k127_7502028_3 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000006276 194.0
PYH2_k127_7502028_4 ABC transporter substrate binding protein K01989 - - 0.0000000000002364 70.0
PYH2_k127_7505002_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 299.0
PYH2_k127_7505002_1 recombinase activity K06400 - - 0.0000000000000000000000000000000000000000000000000000000009413 213.0
PYH2_k127_7505002_2 Heavy-metal resistance - - - 0.00000000000000000000000000000000000005962 152.0
PYH2_k127_7505002_3 PFAM response regulator receiver - - - 0.0000000000000000000213 94.0
PYH2_k127_7505002_4 PFAM DNA methylase N-4 N-6 domain protein - - - 0.0000000000004451 78.0
PYH2_k127_7522434_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 309.0
PYH2_k127_7522434_1 SecA preprotein cross-linking domain - - - 0.0000000000000000000000000000000000000005579 156.0
PYH2_k127_7543809_0 Protein of unknown function, DUF255 K06888 - - 2.366e-301 936.0
PYH2_k127_7543809_1 DNA polymerase III K02342 - 2.7.7.7 1.15e-233 733.0
PYH2_k127_7543809_2 Transmembrane secretion effector - - - 1.022e-212 675.0
PYH2_k127_7543809_3 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 491.0
PYH2_k127_7543809_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 369.0
PYH2_k127_7543809_5 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 331.0
PYH2_k127_757004_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 2.613e-249 775.0
PYH2_k127_757004_1 AMP-dependent synthetase - - - 1.798e-209 669.0
PYH2_k127_757004_2 Trypsin-like peptidase domain - - - 7.321e-195 618.0
PYH2_k127_757004_3 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 360.0
PYH2_k127_757004_4 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 340.0
PYH2_k127_757004_5 regulatory - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 303.0
PYH2_k127_757004_6 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000000000000297 202.0
PYH2_k127_757004_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000007845 118.0
PYH2_k127_7585117_0 Cytochrome c554 and c-prime - - - 2.758e-260 820.0
PYH2_k127_7585117_1 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 557.0
PYH2_k127_7585117_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 466.0
PYH2_k127_7585117_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 357.0
PYH2_k127_7585117_4 Divergent 4Fe-4S mono-cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 317.0
PYH2_k127_7585117_5 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005329 249.0
PYH2_k127_7585117_6 Pfam cytochrome c K08738 - - 0.0000000000000000000000000000000000004575 144.0
PYH2_k127_7592097_0 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 534.0
PYH2_k127_7592097_1 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 347.0
PYH2_k127_7592097_2 - - - - 0.0000000000000000000000000000000000000009194 151.0
PYH2_k127_7605697_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1384.0
PYH2_k127_7605697_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000002779 244.0
PYH2_k127_7631787_0 AMP-binding enzyme C-terminal domain K00666 - - 1.008e-195 615.0
PYH2_k127_7631787_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 459.0
PYH2_k127_7631787_2 Peptidase family M3 K01284 - 3.4.15.5 0.000000000000000000000000000000000000000000000000000000000000001398 224.0
PYH2_k127_7631787_3 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000001831 213.0
PYH2_k127_7631787_4 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000005391 94.0
PYH2_k127_7631787_5 Methyltransferase domain - - - 0.000000000000001103 79.0
PYH2_k127_7631787_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000003781 76.0
PYH2_k127_7631787_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00004859 54.0
PYH2_k127_7649126_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1382.0
PYH2_k127_7649126_1 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 494.0
PYH2_k127_7649126_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 377.0
PYH2_k127_7649126_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 316.0
PYH2_k127_7649126_4 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000000000000000000000000002214 201.0
PYH2_k127_7649126_5 Biopolymer transport protein K03559,K03560 - - 0.0000000000000000000000000000000000000000005867 161.0
PYH2_k127_7672918_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 372.0
PYH2_k127_7672918_1 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000000000000001101 216.0
PYH2_k127_7672918_2 GYD domain - - - 0.00000000000000000000000000000001198 129.0
PYH2_k127_7682204_0 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 6.4e-323 1011.0
PYH2_k127_7682204_1 Amidohydrolase family K18456 - 3.5.4.32 3.625e-255 794.0
PYH2_k127_7682204_10 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 475.0
PYH2_k127_7682204_11 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 390.0
PYH2_k127_7682204_12 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 322.0
PYH2_k127_7682204_13 Formyl transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002009 293.0
PYH2_k127_7682204_14 Cmp dcmp deaminase zinc-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000007229 231.0
PYH2_k127_7682204_15 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000000000000000001188 186.0
PYH2_k127_7682204_16 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000005305 154.0
PYH2_k127_7682204_17 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000006425 138.0
PYH2_k127_7682204_18 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000006149 102.0
PYH2_k127_7682204_19 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000001258 59.0
PYH2_k127_7682204_2 PFAM Xanthine uracil vitamin C permease K03458 - - 1.44e-249 779.0
PYH2_k127_7682204_20 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07544,K07749 - 2.8.3.15,2.8.3.16 0.00001551 48.0
PYH2_k127_7682204_3 Urate oxidase N-terminal - - - 2.001e-227 708.0
PYH2_k127_7682204_4 peptidase dimerisation domain protein - - - 1.642e-220 692.0
PYH2_k127_7682204_5 deacetylase K01452 - 3.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 608.0
PYH2_k127_7682204_6 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 556.0
PYH2_k127_7682204_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 559.0
PYH2_k127_7682204_8 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 519.0
PYH2_k127_7682204_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 487.0
PYH2_k127_7693083_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 560.0
PYH2_k127_7693083_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 555.0
PYH2_k127_7693083_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 524.0
PYH2_k127_7693083_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 516.0
PYH2_k127_7693083_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 405.0
PYH2_k127_7701369_0 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000005933 213.0
PYH2_k127_7701369_1 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000002441 149.0
PYH2_k127_7713237_0 Tryptophan halogenase K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 550.0
PYH2_k127_7713237_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 355.0
PYH2_k127_7713237_2 - - - - 0.000000000000000000000000000000000000000000002517 174.0
PYH2_k127_7721380_0 Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002926 299.0
PYH2_k127_7721380_1 phenylacetate-CoA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000005513 237.0
PYH2_k127_7721380_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000001954 187.0
PYH2_k127_7721380_3 Protein of unknown function (DUF2905) - - - 0.000000000000000000000000234 106.0
PYH2_k127_7721380_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0001658 50.0
PYH2_k127_7734264_0 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 337.0
PYH2_k127_7734264_2 - - - - 0.00000000000000000008732 93.0
PYH2_k127_7734264_3 7TM diverse intracellular signalling - - - 0.000000000005241 76.0
PYH2_k127_7738724_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.231e-292 905.0
PYH2_k127_7738724_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 291.0
PYH2_k127_7743175_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 3.583e-209 659.0
PYH2_k127_7743175_1 PFAM fatty acid desaturase K00507 - 1.14.19.1 7.282e-202 643.0
PYH2_k127_7743175_10 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000003046 207.0
PYH2_k127_7743175_11 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000000003049 193.0
PYH2_k127_7743175_12 Water Stress and Hypersensitive response - - - 0.000000000000000000000000000000000000000000000000005293 186.0
PYH2_k127_7743175_13 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000004302 174.0
PYH2_k127_7743175_14 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000000001621 169.0
PYH2_k127_7743175_15 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000001538 149.0
PYH2_k127_7743175_16 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000005554 122.0
PYH2_k127_7743175_17 Winged helix-turn helix - - - 0.000000000000000000000000001487 113.0
PYH2_k127_7743175_18 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000001821 102.0
PYH2_k127_7743175_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 595.0
PYH2_k127_7743175_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 574.0
PYH2_k127_7743175_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 502.0
PYH2_k127_7743175_5 Transcriptional regulator, Crp Fnr family K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 368.0
PYH2_k127_7743175_6 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 343.0
PYH2_k127_7743175_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 304.0
PYH2_k127_7743175_8 PFAM NnrUfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000185 248.0
PYH2_k127_7743175_9 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001674 236.0
PYH2_k127_7753714_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 387.0
PYH2_k127_7753714_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000002941 251.0
PYH2_k127_7753714_2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000007114 188.0
PYH2_k127_7753714_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000001657 79.0
PYH2_k127_77550_0 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 3.7e-322 993.0
PYH2_k127_77550_1 His Kinase A (phospho-acceptor) domain - - - 1.47e-263 822.0
PYH2_k127_77550_10 - - - - 0.00000000000000000003935 95.0
PYH2_k127_77550_11 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000692 67.0
PYH2_k127_77550_2 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 414.0
PYH2_k127_77550_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 349.0
PYH2_k127_77550_4 - - - - 0.000000000000000000000000000000000000000000000000000000002178 203.0
PYH2_k127_77550_5 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.0000000000000000000000000000000000000000000000000009574 193.0
PYH2_k127_77550_6 Toxin-antitoxin system, toxin component, PIN family - - - 0.0000000000000000000000000000000000000000000000002656 179.0
PYH2_k127_77550_7 Fumarate reductase subunit C K00246 - - 0.00000000000000000000000000000000000000000002025 176.0
PYH2_k127_77550_8 - - - - 0.000000000000000000000005309 102.0
PYH2_k127_7768897_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K16874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 529.0
PYH2_k127_7768897_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 324.0
PYH2_k127_7768897_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0004358 48.0
PYH2_k127_7771952_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.156e-281 873.0
PYH2_k127_7771952_1 Serine threonine protein kinase K12132 - 2.7.11.1 1.437e-210 667.0
PYH2_k127_7771952_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 330.0
PYH2_k127_7771952_3 Predicted membrane protein (DUF2214) K08983 - - 0.0000000000000000000000000000000000000000000000000000002968 197.0
PYH2_k127_7771952_4 Sporulation related domain - - - 0.0000000000000000000000001056 109.0
PYH2_k127_7771952_5 - - - - 0.000000000000000007164 89.0
PYH2_k127_7775050_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.266e-239 747.0
PYH2_k127_7775050_1 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 364.0
PYH2_k127_7775050_2 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000004412 204.0
PYH2_k127_7783780_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01608 - 4.1.1.47 0.0 1024.0
PYH2_k127_7783780_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 560.0
PYH2_k127_7783780_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 476.0
PYH2_k127_7783780_3 6-phosphogluconate dehydrogenase, NAD-binding K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 444.0
PYH2_k127_7783780_4 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 436.0
PYH2_k127_7783780_5 Membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 403.0
PYH2_k127_7791081_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1279.0
PYH2_k127_7791081_1 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 315.0
PYH2_k127_7791081_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000003769 167.0
PYH2_k127_7791081_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000104 165.0
PYH2_k127_7791081_4 Thioesterase - - - 0.0000000000000000000000000000000000000000001151 163.0
PYH2_k127_7791081_5 transcriptional regulator - - - 0.00000000000000000000000000000000000002757 148.0
PYH2_k127_7803824_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 537.0
PYH2_k127_7803824_1 Von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 465.0
PYH2_k127_7803824_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 404.0
PYH2_k127_7803824_3 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 330.0
PYH2_k127_7803824_4 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000132 112.0
PYH2_k127_7803824_5 Ammonium Transporter K03320,K06580 - - 0.00000000000000000000001657 100.0
PYH2_k127_7803824_6 Protein of unknown function DUF86 - - - 0.000000000000000000007593 96.0
PYH2_k127_7808074_0 Flagellar motor switch K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 537.0
PYH2_k127_7808074_1 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000768 180.0
PYH2_k127_7813248_0 Protein of unknown function - - - 2.14e-276 871.0
PYH2_k127_7813248_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 370.0
PYH2_k127_7813248_2 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.00002656 46.0
PYH2_k127_7815675_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01539 - 3.6.3.9 0.0 1245.0
PYH2_k127_7815675_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 592.0
PYH2_k127_7815675_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000001098 235.0
PYH2_k127_7815675_3 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000006673 139.0
PYH2_k127_7815675_4 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000001878 138.0
PYH2_k127_7815675_5 Glycine-zipper domain - - - 0.000000000000000000000000002195 120.0
PYH2_k127_7815675_6 - - - - 0.00000000000000002867 91.0
PYH2_k127_7815675_7 Protein of unknown function (DUF3606) - - - 0.000000000004491 70.0
PYH2_k127_7825005_0 peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 451.0
PYH2_k127_7825005_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 390.0
PYH2_k127_7825005_2 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 302.0
PYH2_k127_7825005_3 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.0000003625 52.0
PYH2_k127_7825216_0 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 3.614e-198 621.0
PYH2_k127_7825216_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 494.0
PYH2_k127_7825216_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000009816 152.0
PYH2_k127_7841448_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1437.0
PYH2_k127_7841448_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1373.0
PYH2_k127_7841448_2 CoA-transferase family III - - - 7.371e-206 646.0
PYH2_k127_7841448_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 397.0
PYH2_k127_7841448_4 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002971 282.0
PYH2_k127_7841448_5 [2Fe-2S] binding domain K03518,K04107 - 1.2.5.3,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002001 262.0
PYH2_k127_7841448_6 CO dehydrogenase flavoprotein - - - 0.000003911 50.0
PYH2_k127_7843287_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 482.0
PYH2_k127_7843287_1 - - - - 0.00000000000000000000000000000000000001552 156.0
PYH2_k127_7856535_0 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007236 281.0
PYH2_k127_7856535_1 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000003598 183.0
PYH2_k127_7856535_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000008932 83.0
PYH2_k127_7856535_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000005848 82.0
PYH2_k127_7861651_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 6.648e-253 788.0
PYH2_k127_7861651_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 574.0
PYH2_k127_7861651_2 LysR substrate binding domain K18900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 376.0
PYH2_k127_7861651_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 327.0
PYH2_k127_7861651_4 Staphylococcal nuclease homologue - - - 0.000000000000000000000000000000000000000000000000001574 188.0
PYH2_k127_7861651_5 Auxin binding protein - - - 0.000000000000000000000000000000000000000000005088 168.0
PYH2_k127_7861651_6 - - - - 0.000000000000000000000000000000002471 138.0
PYH2_k127_7861651_7 - - - - 0.000000000000000000000000000000006807 128.0
PYH2_k127_7861651_8 helicase superfamily c-terminal domain K03724 - - 0.00000000009102 75.0
PYH2_k127_7882299_0 Male sterility protein - - - 0.0 1064.0
PYH2_k127_7882299_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 271.0
PYH2_k127_7882299_3 - - - - 0.0000000000000000000000000000000000003864 148.0
PYH2_k127_7882299_4 DUF167 K09131 - - 0.0000000000000000005275 91.0
PYH2_k127_7882299_5 Cation efflux family - - - 0.00000000000000001105 84.0
PYH2_k127_7904636_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.504e-301 939.0
PYH2_k127_7904636_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.944e-274 860.0
PYH2_k127_7904678_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.964e-241 750.0
PYH2_k127_7904678_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 567.0
PYH2_k127_7904678_2 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000001534 241.0
PYH2_k127_7904678_3 - - - - 0.00000000000000000000000000000000000002654 149.0
PYH2_k127_7904678_4 LysE type translocator K05834 - - 0.000000000000000000000000000001104 126.0
PYH2_k127_7904678_5 Zinc-finger domain - - - 0.0000000000000000000000000005952 113.0
PYH2_k127_7904678_6 Protein of unknown function (DUF1232) - - - 0.00000000000000000000001842 101.0
PYH2_k127_7921383_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 557.0
PYH2_k127_7952766_0 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 493.0
PYH2_k127_7952766_1 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 354.0
PYH2_k127_7952766_2 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 344.0
PYH2_k127_7952766_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856 - 5.5.1.1 0.000000000000000000000000000000000000000000000000003569 187.0
PYH2_k127_7952766_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000004273 109.0
PYH2_k127_7968138_0 PFAM transposase IS66 - - - 4.956e-218 689.0
PYH2_k127_7968138_1 PFAM IS66 Orf2 family protein - - - 0.000000000000000000000000000000000000000000000000007439 185.0
PYH2_k127_7968138_2 Excisionase - - - 0.000000000317 64.0
PYH2_k127_7968138_3 transposase activity K07483 - - 0.000000003035 63.0
PYH2_k127_796838_0 PFAM AMP-dependent synthetase and ligase K00666 - - 6.803e-315 970.0
PYH2_k127_796838_1 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 385.0
PYH2_k127_796838_2 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 329.0
PYH2_k127_796838_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001093 244.0
PYH2_k127_796838_4 Domain of unknown function (DUF4864) - - - 0.000000000000000000000000000007281 128.0
PYH2_k127_797810_0 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 346.0
PYH2_k127_797810_1 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 298.0
PYH2_k127_8009686_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1059.0
PYH2_k127_8009686_1 Histidine kinase-like ATPases - - - 8.608e-238 757.0
PYH2_k127_8009686_10 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 382.0
PYH2_k127_8009686_11 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 358.0
PYH2_k127_8009686_12 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 308.0
PYH2_k127_8009686_13 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000007786 261.0
PYH2_k127_8009686_14 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000004 243.0
PYH2_k127_8009686_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000001642 177.0
PYH2_k127_8009686_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 8.873e-212 665.0
PYH2_k127_8009686_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 6.458e-207 647.0
PYH2_k127_8009686_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 602.0
PYH2_k127_8009686_5 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 584.0
PYH2_k127_8009686_6 Phosphoribulokinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 561.0
PYH2_k127_8009686_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 520.0
PYH2_k127_8009686_8 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 504.0
PYH2_k127_8009686_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 398.0
PYH2_k127_8014261_0 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 479.0
PYH2_k127_8014261_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 406.0
PYH2_k127_8014261_2 Protein of unknown function (DUF455) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 345.0
PYH2_k127_8014261_3 transferase hexapeptide - - - 0.000000000000000000000000000000000000000000000000000000000004796 218.0
PYH2_k127_8016711_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 7.768e-248 768.0
PYH2_k127_8016711_1 PFAM 20S proteasome, A and B subunits K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 457.0
PYH2_k127_8016711_2 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 426.0
PYH2_k127_8016711_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 363.0
PYH2_k127_8016711_4 membrane protein, terc - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 318.0
PYH2_k127_8016711_5 YHS domain protein - - - 0.00000000000000000000000000000001118 133.0
PYH2_k127_8016711_6 Belongs to the universal stress protein A family - - - 0.00000000000000000000009093 112.0
PYH2_k127_8016711_7 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000003677 55.0
PYH2_k127_8033482_0 COG2133 Glucose sorbosone dehydrogenases K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 474.0
PYH2_k127_8033482_1 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 447.0
PYH2_k127_8033482_2 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 438.0
PYH2_k127_8033482_3 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 362.0
PYH2_k127_8033482_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 289.0
PYH2_k127_8033482_5 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000002094 213.0
PYH2_k127_8033482_6 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000003202 179.0
PYH2_k127_8049264_0 abc-type branched-chain amino acid transport K01999 - - 1.23e-251 781.0
PYH2_k127_8049264_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 499.0
PYH2_k127_8049264_2 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 463.0
PYH2_k127_8049264_3 abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 367.0
PYH2_k127_8049264_4 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 324.0
PYH2_k127_8049264_5 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000295 278.0
PYH2_k127_8052690_0 Formate dehydrogenase, alpha subunit K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1067.0
PYH2_k127_8052690_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 452.0
PYH2_k127_8076918_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1029.0
PYH2_k127_8076918_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000000000004807 203.0
PYH2_k127_8076918_2 regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000000004773 179.0
PYH2_k127_8076918_3 dehydrogenase - - - 0.000001438 50.0
PYH2_k127_8078764_0 Heat shock 70 kDa protein K04043 - - 3.062e-272 849.0
PYH2_k127_8090392_0 CO dehydrogenase flavoprotein domain protein K13481 - 1.17.1.4 1.315e-209 662.0
PYH2_k127_8090392_1 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 433.0
PYH2_k127_8090392_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K13482 - 1.17.1.4 0.0000000000000000000000000000000000000000000000001027 180.0
PYH2_k127_8107446_0 ABC transporter K06020 - 3.6.3.25 1.62e-262 812.0
PYH2_k127_8107446_1 domain, Protein - - - 0.000000000000000000000000000000000000000004249 173.0
PYH2_k127_8107446_2 lipolytic protein G-D-S-L family - - - 0.00000000000000001433 85.0
PYH2_k127_8117637_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1735.0
PYH2_k127_8117637_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1080.0
PYH2_k127_8117637_10 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 323.0
PYH2_k127_8117637_11 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 302.0
PYH2_k127_8117637_12 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000007332 222.0
PYH2_k127_8117637_13 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000001224 188.0
PYH2_k127_8117637_14 - - - - 0.0000000000000003783 82.0
PYH2_k127_8117637_2 Sulfate permease family K03321 - - 2.242e-230 737.0
PYH2_k127_8117637_3 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.057e-194 616.0
PYH2_k127_8117637_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 490.0
PYH2_k127_8117637_5 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 494.0
PYH2_k127_8117637_6 4Fe-4S binding domain K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 463.0
PYH2_k127_8117637_7 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 448.0
PYH2_k127_8117637_8 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 438.0
PYH2_k127_8117637_9 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 349.0
PYH2_k127_8117752_0 PFAM AMP-dependent synthetase and ligase K18661 - - 2.545e-249 781.0
PYH2_k127_8117752_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.199e-210 664.0
PYH2_k127_8117752_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 471.0
PYH2_k127_8117752_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 468.0
PYH2_k127_8117752_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000445 93.0
PYH2_k127_8117752_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000824 64.0
PYH2_k127_8125633_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 579.0
PYH2_k127_8125633_1 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 534.0
PYH2_k127_8125633_2 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 524.0
PYH2_k127_8125633_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 377.0
PYH2_k127_8125633_4 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 347.0
PYH2_k127_8125633_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 310.0
PYH2_k127_8125633_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007013 285.0
PYH2_k127_8126414_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 566.0
PYH2_k127_8126414_1 Pfam ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 322.0
PYH2_k127_8126414_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000007082 130.0
PYH2_k127_8127569_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 2.978e-215 674.0
PYH2_k127_8127569_1 AMP-binding enzyme K01912 - 6.2.1.30 1.18e-208 656.0
PYH2_k127_8127569_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 559.0
PYH2_k127_8127569_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 488.0
PYH2_k127_8127569_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 383.0
PYH2_k127_8127569_5 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 312.0
PYH2_k127_8127569_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000004391 201.0
PYH2_k127_8127569_7 - - - - 0.000000000000000000000678 98.0
PYH2_k127_8138216_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 476.0
PYH2_k127_8138216_1 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 299.0
PYH2_k127_8235637_0 ABC-type dipeptide transport system, periplasmic component K02035 - - 7.049e-254 790.0
PYH2_k127_8235637_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 331.0
PYH2_k127_8235637_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003252 254.0
PYH2_k127_8235637_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000004136 209.0
PYH2_k127_8235637_4 Belongs to the ABC transporter superfamily K02031,K02032,K12371 - - 0.000000000003251 68.0
PYH2_k127_8253530_0 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 343.0
PYH2_k127_8253530_1 phosphoglycerate mutase K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005033 271.0
PYH2_k127_8253530_2 Domain of unknown function (DUF1840) - - - 0.00000002521 56.0
PYH2_k127_8290736_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.628e-257 798.0
PYH2_k127_8290736_1 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 572.0
PYH2_k127_8290736_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 323.0
PYH2_k127_8290736_3 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000005878 228.0
PYH2_k127_8290736_4 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000008846 210.0
PYH2_k127_8290736_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000117 189.0
PYH2_k127_8290736_6 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000001645 197.0
PYH2_k127_8304135_0 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 548.0
PYH2_k127_8304135_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 381.0
PYH2_k127_8304135_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000004361 60.0
PYH2_k127_8320510_0 dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 542.0
PYH2_k127_8320510_1 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 513.0
PYH2_k127_8320510_2 Glycosyltransferase family 17 - - - 0.000000000000000000000000000000000000000000000000005649 192.0
PYH2_k127_8327918_0 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 292.0
PYH2_k127_8327918_1 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002911 279.0
PYH2_k127_8330896_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 472.0
PYH2_k127_8330896_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 405.0
PYH2_k127_8330896_2 Abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 369.0
PYH2_k127_8330896_3 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001404 252.0
PYH2_k127_8330896_4 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000001812 219.0
PYH2_k127_8330896_5 Protein of unknown function (DUF454) K09790 - - 0.000000000000000000000000000000000000000000001733 169.0
PYH2_k127_8330896_6 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000577 146.0
PYH2_k127_8330896_7 RibD C-terminal domain - - - 0.000000000000000002488 96.0
PYH2_k127_8330896_8 RibD C-terminal domain - - - 0.00000000263 61.0
PYH2_k127_8358965_0 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 406.0
PYH2_k127_8358965_1 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 401.0
PYH2_k127_8358965_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 366.0
PYH2_k127_8358965_3 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000007236 187.0
PYH2_k127_8390068_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 572.0
PYH2_k127_8390068_1 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 510.0
PYH2_k127_8390068_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000004821 273.0
PYH2_k127_8390068_3 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000009333 74.0
PYH2_k127_8392187_0 flagellar motor switch protein K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 520.0
PYH2_k127_8392187_1 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008738 266.0
PYH2_k127_8392187_2 Flagellar assembly protein FliH K02411 - - 0.000000000000000000000000000000000000000000000000000001264 200.0
PYH2_k127_8392187_3 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.0000000000000000000000000002162 126.0
PYH2_k127_8422122_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.34e-301 930.0
PYH2_k127_8422122_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 529.0
PYH2_k127_8422122_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 329.0
PYH2_k127_8422122_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000000000171 186.0
PYH2_k127_8422122_4 - - - - 0.000000000000000000000000000000000000009489 150.0
PYH2_k127_8422122_5 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000003975 126.0
PYH2_k127_8422122_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000007621 99.0
PYH2_k127_8422122_7 Aldehyde dehydrogenase K02618 - 1.2.1.91,3.3.2.12 0.000000001667 58.0
PYH2_k127_8447480_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1281.0
PYH2_k127_8447480_1 acyl-CoA dehydrogenase - - - 0.0 1012.0
PYH2_k127_8447480_2 Belongs to the thiolase family K00632 - 2.3.1.16 7.093e-207 648.0
PYH2_k127_8447480_3 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 372.0
PYH2_k127_8447480_4 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000000000000000000000434 216.0
PYH2_k127_8447480_5 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000000000000000000003011 208.0
PYH2_k127_8447480_6 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000009698 197.0
PYH2_k127_8453463_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 8.621e-256 799.0
PYH2_k127_8453463_1 Cytochrome b(N-terminal)/b6/petB - - - 1.926e-225 715.0
PYH2_k127_8453463_2 Trypsin K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 494.0
PYH2_k127_8453463_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 374.0
PYH2_k127_8453463_4 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 348.0
PYH2_k127_8453463_5 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 295.0
PYH2_k127_8453463_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000009583 276.0
PYH2_k127_8453463_7 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000002366 221.0
PYH2_k127_8453463_8 - - - - 0.000000000001128 70.0
PYH2_k127_8461180_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1613.0
PYH2_k127_8461180_1 Histidine kinase K11711 - 2.7.13.3 0.0 1158.0
PYH2_k127_8461180_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.00000000000000000000000000000000005692 135.0
PYH2_k127_8461180_11 D-isomer specific 2-hydroxyacid dehydrogenase K00090 - 1.1.1.215,1.1.1.79,1.1.1.81 0.000000000000000000000000001823 112.0
PYH2_k127_8461180_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0 1040.0
PYH2_k127_8461180_3 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 5e-323 1000.0
PYH2_k127_8461180_4 RmuC family K09760 - - 3.247e-210 663.0
PYH2_k127_8461180_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 458.0
PYH2_k127_8461180_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 435.0
PYH2_k127_8461180_7 Regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 386.0
PYH2_k127_8461180_8 2Fe-2S -binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000008078 263.0
PYH2_k127_8461180_9 PFAM Glutaredoxin - - - 0.0000000000000000000000000000000000000000000000754 175.0
PYH2_k127_8468880_0 twitching motility protein K02670 - - 3.176e-198 622.0
PYH2_k127_8468880_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000111 252.0
PYH2_k127_8532975_0 Tetratricopeptide repeat - - - 2.942e-199 636.0
PYH2_k127_8532975_1 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 591.0
PYH2_k127_8532975_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 374.0
PYH2_k127_8532975_3 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000001303 115.0
PYH2_k127_8536412_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 540.0
PYH2_k127_8536412_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 306.0
PYH2_k127_8536412_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000819 241.0
PYH2_k127_8536412_3 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000001658 141.0
PYH2_k127_8540939_0 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000007134 230.0
PYH2_k127_8540939_1 Phospholipase D Transphosphatidylase K06132 - - 0.000000000000000000000000000000000000000000000001046 184.0
PYH2_k127_8540939_2 Phosphopantetheine attachment site - - - 0.0000000000000000001332 93.0
PYH2_k127_8540939_3 e3 binding domain K00627 - 2.3.1.12 0.00000000004998 64.0
PYH2_k127_8562036_0 Heparinase II/III N-terminus - - - 1.483e-246 789.0
PYH2_k127_8562036_1 PFAM Glycosyl transferases group 1 K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 475.0
PYH2_k127_8569649_0 protein conserved in bacteria K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 510.0
PYH2_k127_8569649_1 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 433.0
PYH2_k127_8569649_2 Sodium Bile acid symporter family - - - 0.000021 58.0
PYH2_k127_8575400_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 545.0
PYH2_k127_8575400_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 396.0
PYH2_k127_8575400_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 312.0
PYH2_k127_8575400_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000009066 236.0
PYH2_k127_8577950_0 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 9.469e-281 876.0
PYH2_k127_8577950_1 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 433.0
PYH2_k127_8577950_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 345.0
PYH2_k127_8577950_3 Lysine methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 316.0
PYH2_k127_8578901_0 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 434.0
PYH2_k127_8578901_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 316.0
PYH2_k127_8578901_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000001716 138.0
PYH2_k127_8578901_3 Domain of unknown function (DUF4214) - - - 0.00000001511 66.0
PYH2_k127_8588567_0 type VI secretion protein K11891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 462.0
PYH2_k127_8588567_1 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001049 253.0
PYH2_k127_8588567_2 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000001014 152.0
PYH2_k127_8591654_0 binding-protein-dependent transport systems inner membrane component K02011 - - 2.838e-286 887.0
PYH2_k127_8591654_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000006346 79.0
PYH2_k127_8600091_0 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 371.0
PYH2_k127_8600091_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 354.0
PYH2_k127_8600091_2 TIGRFAM type IV VI secretion system protein, DotU family K11892 - - 0.000000000000000000000000000000000000000000000000000000004276 209.0
PYH2_k127_8600091_3 - - - - 0.000000000000000000000000000000000000000000000001308 186.0
PYH2_k127_8600091_4 FHA domain K07169,K11913 - - 0.0000000001405 67.0
PYH2_k127_8616802_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.675e-282 871.0
PYH2_k127_8616802_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.109e-209 654.0
PYH2_k127_8616802_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 3.078e-199 627.0
PYH2_k127_8616802_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 408.0
PYH2_k127_8616802_4 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000008102 184.0
PYH2_k127_8616802_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000897 107.0
PYH2_k127_8616802_6 response to toxic substance - - - 0.00001222 57.0
PYH2_k127_8616941_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1201.0
PYH2_k127_8616941_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0 1020.0
PYH2_k127_8616941_10 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 467.0
PYH2_k127_8616941_11 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 471.0
PYH2_k127_8616941_12 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 460.0
PYH2_k127_8616941_13 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 450.0
PYH2_k127_8616941_14 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 396.0
PYH2_k127_8616941_15 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 370.0
PYH2_k127_8616941_16 domain, Protein K13735,K15125,K15531 - 3.2.1.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 343.0
PYH2_k127_8616941_17 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002154 274.0
PYH2_k127_8616941_18 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004402 246.0
PYH2_k127_8616941_19 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009524 252.0
PYH2_k127_8616941_2 Protein of unknown function (DUF1631) - - - 2.401e-319 993.0
PYH2_k127_8616941_20 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000007903 245.0
PYH2_k127_8616941_21 Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000000335 194.0
PYH2_k127_8616941_22 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000000000000000000002767 177.0
PYH2_k127_8616941_23 Ribosomal-protein-alanine acetyltransferase K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000003844 144.0
PYH2_k127_8616941_24 lipase activity - - - 0.00000000000000000000000000000001053 140.0
PYH2_k127_8616941_25 - - - - 0.000000000000000000000000000001161 128.0
PYH2_k127_8616941_26 Domain of unknown function (DUF4347) - - - 0.000001691 62.0
PYH2_k127_8616941_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.084e-251 782.0
PYH2_k127_8616941_4 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 6.512e-196 623.0
PYH2_k127_8616941_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 547.0
PYH2_k127_8616941_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 547.0
PYH2_k127_8616941_7 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 537.0
PYH2_k127_8616941_8 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 521.0
PYH2_k127_8616941_9 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 510.0
PYH2_k127_8625107_0 FAD linked oxidase domain protein - - - 0.0 1252.0
PYH2_k127_8625107_1 PFAM extracellular solute-binding protein family 1 K05813 - - 3.708e-250 781.0
PYH2_k127_8625107_2 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 481.0
PYH2_k127_8625107_3 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 466.0
PYH2_k127_8625107_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 441.0
PYH2_k127_8625657_0 Transketolase, pyrimidine binding domain K21417 - - 7.864e-199 623.0
PYH2_k127_8625657_1 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 556.0
PYH2_k127_8625657_2 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 535.0
PYH2_k127_8625657_3 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000001193 116.0
PYH2_k127_8625657_4 lipoate-protein ligase A - - - 0.0000000000000005767 78.0
PYH2_k127_8635977_0 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 362.0
PYH2_k127_8635977_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002657 268.0
PYH2_k127_8635977_2 Carboxylesterase family K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000001622 223.0
PYH2_k127_8640895_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 0.0 1259.0
PYH2_k127_8640895_1 DNA polymerase X family K02347 - - 3.248e-235 742.0
PYH2_k127_8640895_2 Psort location Cytoplasmic, score 7.50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 515.0
PYH2_k127_8640895_3 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 357.0
PYH2_k127_8640895_4 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 308.0
PYH2_k127_8640895_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000161 232.0
PYH2_k127_8640895_6 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000003073 224.0
PYH2_k127_8640895_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.000000000000000000000000000000000000000000000000000003189 198.0
PYH2_k127_8640895_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000004713 142.0
PYH2_k127_8656848_0 Amidohydrolase K10220 - 4.2.1.83 1.29e-207 671.0
PYH2_k127_8656848_1 PrpF protein K16514 - 5.3.2.8 3.365e-199 625.0
PYH2_k127_8656848_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 367.0
PYH2_k127_8656848_11 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003815 271.0
PYH2_k127_8656848_12 - - - - 0.00000000000000000001689 95.0
PYH2_k127_8656848_2 PFAM Amidohydrolase 2 K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 591.0
PYH2_k127_8656848_3 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 550.0
PYH2_k127_8656848_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 519.0
PYH2_k127_8656848_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 494.0
PYH2_k127_8656848_6 Thioesterase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 497.0
PYH2_k127_8656848_7 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 483.0
PYH2_k127_8656848_8 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 443.0
PYH2_k127_8656848_9 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 393.0
PYH2_k127_8656979_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1845.0
PYH2_k127_8656979_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 367.0
PYH2_k127_8658270_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 420.0
PYH2_k127_8658270_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000003328 236.0
PYH2_k127_8658270_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000006222 192.0
PYH2_k127_8658270_3 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.0000000000000000000000008065 115.0
PYH2_k127_8658270_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00001538 55.0
PYH2_k127_8676023_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 602.0
PYH2_k127_8676023_1 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 484.0
PYH2_k127_8676023_2 Domain of unknown function (DUF4178) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 348.0
PYH2_k127_8676023_3 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001818 263.0
PYH2_k127_8676023_4 ROK family - - - 0.000003366 59.0
PYH2_k127_8676023_5 ROK family - - - 0.0003443 44.0
PYH2_k127_8676545_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 477.0
PYH2_k127_8676545_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000003663 156.0
PYH2_k127_8676545_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000009215 148.0
PYH2_k127_8676545_3 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0000000000000003113 85.0
PYH2_k127_8686855_0 type II secretion system protein E K02454 - - 2.822e-273 852.0
PYH2_k127_8686855_1 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 358.0
PYH2_k127_8686855_2 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001533 240.0
PYH2_k127_8686855_3 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000003124 232.0
PYH2_k127_8686855_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000001706 142.0
PYH2_k127_8702764_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 344.0
PYH2_k127_8702764_1 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 327.0
PYH2_k127_8702764_2 Bacterial regulatory proteins, luxR family K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 317.0
PYH2_k127_8702764_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 302.0
PYH2_k127_8702764_4 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.000000000000000000000000000000000000000000000001928 177.0
PYH2_k127_8702764_5 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000007552 95.0
PYH2_k127_8703669_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 448.0
PYH2_k127_8703669_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 346.0
PYH2_k127_8703669_2 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 315.0
PYH2_k127_8704294_0 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 588.0
PYH2_k127_8704294_1 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 493.0
PYH2_k127_8704294_2 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000003009 99.0
PYH2_k127_8716065_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K13796 - - 0.000000003667 59.0
PYH2_k127_8725829_0 TonB dependent receptor K02014 - - 1.124e-229 732.0
PYH2_k127_8725829_1 Ferredoxin--NADP reductase K00384 - 1.8.1.9 1.889e-207 648.0
PYH2_k127_8725829_2 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 566.0
PYH2_k127_8725829_3 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 443.0
PYH2_k127_8725829_4 TIGRFAM phasin family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002962 258.0
PYH2_k127_8725829_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000001711 211.0
PYH2_k127_8729654_0 GTP-binding signal recognition particle K02404 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 471.0
PYH2_k127_8729654_1 bacterial-type flagellum organization K04562 - - 0.0000000000000000000000000000000000000000000000000000002599 214.0
PYH2_k127_8734191_0 Diguanylate cyclase - - - 1.375e-223 714.0
PYH2_k127_8734191_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.379e-214 675.0
PYH2_k127_8734191_2 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 1.082e-203 638.0
PYH2_k127_8734191_3 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 556.0
PYH2_k127_8734191_4 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 451.0
PYH2_k127_8734191_5 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 392.0
PYH2_k127_8734191_6 Domain of unknown function (DUF1840) - - - 0.000000000000000001421 87.0
PYH2_k127_8737801_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 404.0
PYH2_k127_8737801_1 PFAM ABC transporter K02049,K15555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 389.0
PYH2_k127_8737801_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000729 228.0
PYH2_k127_8745526_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 576.0
PYH2_k127_8745526_1 Type IV pilus biogenesis stability protein PilW K02656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 312.0
PYH2_k127_8745526_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000008591 246.0
PYH2_k127_8745526_3 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000000004036 130.0
PYH2_k127_8745526_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000003211 106.0
PYH2_k127_875370_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 535.0
PYH2_k127_875370_1 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 502.0
PYH2_k127_875370_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 391.0
PYH2_k127_875370_3 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 359.0
PYH2_k127_875370_4 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000547 185.0
PYH2_k127_875370_5 - - - - 0.00000004137 61.0
PYH2_k127_8758315_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 2.673e-237 756.0
PYH2_k127_8758315_1 Involved in the TonB-independent uptake of proteins K03641 - - 9.444e-199 626.0
PYH2_k127_8758315_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 443.0
PYH2_k127_8758315_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 328.0
PYH2_k127_8758315_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 316.0
PYH2_k127_8758315_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 304.0
PYH2_k127_8758315_6 heptosyltransferase K12982 - - 0.00000000000000000000000000000000000000000000000000000000000000001173 231.0
PYH2_k127_8758315_7 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000168 188.0
PYH2_k127_8758315_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000002691 175.0
PYH2_k127_8758315_9 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000001307 70.0
PYH2_k127_875954_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1496.0
PYH2_k127_875954_1 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 502.0
PYH2_k127_875954_2 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
PYH2_k127_875954_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 300.0
PYH2_k127_875954_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001871 287.0
PYH2_k127_875954_5 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002344 240.0
PYH2_k127_875954_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000486 204.0
PYH2_k127_8765852_0 PFAM carboxyl transferase K01615 - 4.1.1.70 5.795e-195 612.0
PYH2_k127_8765852_1 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000003456 203.0
PYH2_k127_8765852_2 AAA domain K07133 - - 0.0000000000000004481 78.0
PYH2_k127_8817467_0 Extracellular liganD-binding receptor K01999 - - 3.089e-217 691.0
PYH2_k127_8817467_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 548.0
PYH2_k127_8817467_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 527.0
PYH2_k127_8817467_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 475.0
PYH2_k127_8817467_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 458.0
PYH2_k127_8817467_5 UbiC transcription regulator-associated K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 357.0
PYH2_k127_8817467_6 PFAM ABC transporter related K01995,K10822 - 3.6.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 357.0
PYH2_k127_8817467_7 PFAM ABC transporter related K01996 - - 0.0001645 52.0
PYH2_k127_8827978_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 577.0
PYH2_k127_8827978_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 557.0
PYH2_k127_8827978_2 phosphoribosyltransferase K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000006893 246.0
PYH2_k127_8827978_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000001691 179.0
PYH2_k127_8830611_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 436.0
PYH2_k127_8830611_1 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 357.0
PYH2_k127_8849364_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 552.0
PYH2_k127_8849364_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 325.0
PYH2_k127_8849364_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001592 282.0
PYH2_k127_8853489_0 Pfam Methyltransferase - - - 2.248e-196 625.0
PYH2_k127_8853489_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 492.0
PYH2_k127_8853489_2 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 473.0
PYH2_k127_8853489_3 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 469.0
PYH2_k127_8853489_4 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 415.0
PYH2_k127_8853489_5 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 332.0
PYH2_k127_8853489_6 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.000000000000000000000000000000000000000000000000004192 184.0
PYH2_k127_8853489_7 Glycosyl transferase family 41 - - - 0.00000008907 55.0
PYH2_k127_8860701_0 heat shock protein binding - - - 9.782e-261 818.0
PYH2_k127_8860701_1 Aminotransferase K14267 - 2.6.1.17 9.297e-196 625.0
PYH2_k127_8860701_2 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 595.0
PYH2_k127_8860701_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 568.0
PYH2_k127_8860701_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 477.0
PYH2_k127_8860701_5 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 352.0
PYH2_k127_8860701_6 Alcohol dehydrogenase GroES-like domain K13953,K18382 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 325.0
PYH2_k127_8860701_7 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002118 292.0
PYH2_k127_8860701_8 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 261.0
PYH2_k127_8871812_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K13482 - 1.17.1.4 0.0 1015.0
PYH2_k127_8871812_1 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 522.0
PYH2_k127_8871812_10 - - - - 0.00005111 55.0
PYH2_k127_8871812_2 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 501.0
PYH2_k127_8871812_3 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 372.0
PYH2_k127_8871812_4 TIGRFAM xanthine dehydrogenase accessory protein XdhC K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 329.0
PYH2_k127_8871812_5 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
PYH2_k127_8871812_6 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 306.0
PYH2_k127_8871812_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000002492 249.0
PYH2_k127_8871812_8 PFAM fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000006024 190.0
PYH2_k127_8871812_9 PFAM aromatic amino acid K00500 GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016714,GO:0055114 1.14.16.1 0.00000000000000003524 81.0
PYH2_k127_8899140_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1397.0
PYH2_k127_8899140_1 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 526.0
PYH2_k127_8899140_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 418.0
PYH2_k127_8899140_3 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000000000000000000000000000000000000001957 209.0
PYH2_k127_8899140_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000001162 192.0
PYH2_k127_8899140_5 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000005182 195.0
PYH2_k127_8920775_0 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 412.0
PYH2_k127_8920775_1 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000006522 164.0
PYH2_k127_8926894_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 1.909e-245 762.0
PYH2_k127_8926894_1 Ferrous iron transport protein B K04759 - - 1.408e-242 768.0
PYH2_k127_8926894_10 PFAM aldo keto reductase - - - 0.00000000001324 64.0
PYH2_k127_8926894_11 ATPase family associated with various cellular activities (AAA) - - - 0.00007285 51.0
PYH2_k127_8926894_2 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 8.853e-204 637.0
PYH2_k127_8926894_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 1.679e-195 632.0
PYH2_k127_8926894_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 518.0
PYH2_k127_8926894_5 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 413.0
PYH2_k127_8926894_6 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 353.0
PYH2_k127_8926894_7 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 340.0
PYH2_k127_8926894_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 307.0
PYH2_k127_8926894_9 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000005517 223.0
PYH2_k127_8939854_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1185.0
PYH2_k127_8939854_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.448e-285 902.0
PYH2_k127_8939854_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.938e-233 727.0
PYH2_k127_8939854_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 8.523e-221 709.0
PYH2_k127_8939854_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 457.0
PYH2_k127_8939854_5 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000005402 169.0
PYH2_k127_8953490_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.499e-275 861.0
PYH2_k127_8953490_1 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 559.0
PYH2_k127_8953490_10 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.0000000104 66.0
PYH2_k127_8953490_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 517.0
PYH2_k127_8953490_3 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 511.0
PYH2_k127_8953490_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 463.0
PYH2_k127_8953490_5 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 399.0
PYH2_k127_8953490_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 307.0
PYH2_k127_8953490_7 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 288.0
PYH2_k127_8953490_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000141 289.0
PYH2_k127_8953490_9 5-oxoprolinase K01469 - 3.5.2.9 0.000000000000000000000000000001184 121.0
PYH2_k127_8967244_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1527.0
PYH2_k127_8967244_1 serine dehydratase beta chain K01752 - 4.3.1.17 1.413e-246 766.0
PYH2_k127_8967244_10 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000000000000000000000000000000000000008565 198.0
PYH2_k127_8967244_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000007328 148.0
PYH2_k127_8967244_12 - - - - 0.0000000000000000000000000000000009096 139.0
PYH2_k127_8967244_13 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000006184 129.0
PYH2_k127_8967244_2 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 1.777e-232 725.0
PYH2_k127_8967244_3 PFAM Cys Met metabolism K01740 - 2.5.1.49 1.363e-228 713.0
PYH2_k127_8967244_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 3.679e-196 619.0
PYH2_k127_8967244_5 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 557.0
PYH2_k127_8967244_6 PFAM Phospholipase D Transphosphatidylase K06132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 559.0
PYH2_k127_8967244_7 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001795 250.0
PYH2_k127_8967244_8 coa-binding K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000002332 235.0
PYH2_k127_8967244_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000007615 215.0
PYH2_k127_8973309_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 589.0
PYH2_k127_8973309_1 Flagellar FliJ protein K02413 - - 0.00000000000009811 77.0
PYH2_k127_8976400_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.703e-224 700.0
PYH2_k127_8976400_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 5.275e-205 649.0
PYH2_k127_8976400_2 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006114 284.0
PYH2_k127_8976400_3 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000003912 108.0
PYH2_k127_8976400_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000002196 99.0
PYH2_k127_8978597_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 2.684e-263 814.0
PYH2_k127_8978597_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 411.0
PYH2_k127_8978597_2 - - - - 0.00000000000000000000001061 103.0
PYH2_k127_8989756_0 Extracellular solute-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 603.0
PYH2_k127_8989756_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 428.0
PYH2_k127_8989756_2 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000008398 209.0
PYH2_k127_8993189_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 7.53e-276 864.0
PYH2_k127_8993189_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.428e-250 775.0
PYH2_k127_8993189_10 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000001434 210.0
PYH2_k127_8993189_11 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000000002932 190.0
PYH2_k127_8993189_12 CHAD - - - 0.000000000000000000000000000000000000000000000000003151 191.0
PYH2_k127_8993189_13 Belongs to the bacterial ribosomal protein bL31 family K02909 - - 0.0000000000000000000000000000000000000000000004706 169.0
PYH2_k127_8993189_14 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000003435 89.0
PYH2_k127_8993189_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 1.331e-201 646.0
PYH2_k127_8993189_3 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 597.0
PYH2_k127_8993189_4 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 531.0
PYH2_k127_8993189_5 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 516.0
PYH2_k127_8993189_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 482.0
PYH2_k127_8993189_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 476.0
PYH2_k127_8993189_8 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 367.0
PYH2_k127_8993189_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 363.0
PYH2_k127_8993219_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0 1030.0
PYH2_k127_9014745_0 acyl-CoA dehydrogenase - - - 2.217e-218 685.0
PYH2_k127_9014745_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000392 233.0
PYH2_k127_9014745_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000001288 181.0
PYH2_k127_9015814_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 5.041e-227 713.0
PYH2_k127_9015814_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 550.0
PYH2_k127_9015814_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 396.0
PYH2_k127_9015814_3 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000006206 153.0
PYH2_k127_9015905_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.086e-294 909.0
PYH2_k127_9015905_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.545e-218 684.0
PYH2_k127_9015905_2 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 526.0
PYH2_k127_9015905_3 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009543 273.0
PYH2_k127_9015905_4 DJ-1 PfpI family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002442 255.0
PYH2_k127_9015905_5 Nucleoside-binding outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000134 238.0
PYH2_k127_9017084_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 420.0
PYH2_k127_9017084_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 416.0
PYH2_k127_9017084_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004168 285.0
PYH2_k127_9017084_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005451 240.0
PYH2_k127_9017084_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000003801 231.0
PYH2_k127_9017084_5 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000006856 208.0
PYH2_k127_9017084_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000003599 167.0
PYH2_k127_9017084_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000001664 139.0
PYH2_k127_9017084_8 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000007338 75.0
PYH2_k127_9021919_0 Mandelate Racemase Muconate Lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 581.0
PYH2_k127_9021919_1 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000003362 156.0
PYH2_k127_9021919_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000001419 139.0
PYH2_k127_9024405_0 VWA domain containing CoxE-like protein K09989 - - 1.628e-234 729.0
PYH2_k127_9024405_1 ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 524.0
PYH2_k127_9024405_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 504.0
PYH2_k127_9024405_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 306.0
PYH2_k127_9024405_4 Cytochrome c class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 293.0
PYH2_k127_9024405_5 TIGRFAM Cu(I)-responsive transcriptional regulator K19591 - - 0.000000000000000000000000000000000000000000000000001412 190.0
PYH2_k127_9024405_6 Heavy-metal-associated domain K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000001443 163.0
PYH2_k127_9024405_7 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000000000005514 156.0
PYH2_k127_9035972_0 GTP-binding protein K06207 - - 0.0 1043.0
PYH2_k127_9035972_1 Formate--tetrahydrofolate ligase - - - 2.448e-242 772.0
PYH2_k127_9035972_2 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 523.0
PYH2_k127_9035972_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 361.0
PYH2_k127_9035972_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 283.0
PYH2_k127_9035972_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000004649 122.0
PYH2_k127_9040147_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 595.0
PYH2_k127_9040147_1 GTP-binding signal recognition particle K02404 - - 0.000000000000000000000000000001256 124.0
PYH2_k127_9049481_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.106e-308 948.0
PYH2_k127_9049481_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.505e-278 860.0
PYH2_k127_9049481_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000002396 211.0
PYH2_k127_9049481_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000001759 197.0
PYH2_k127_9049481_12 ATP synthase I chain K02116 - - 0.00000000000000000000000000000000000003636 148.0
PYH2_k127_9049481_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000004228 145.0
PYH2_k127_9049481_14 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000001532 119.0
PYH2_k127_9049481_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 465.0
PYH2_k127_9049481_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 454.0
PYH2_k127_9049481_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 429.0
PYH2_k127_9049481_5 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 399.0
PYH2_k127_9049481_6 XdhC and CoxI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 315.0
PYH2_k127_9049481_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 302.0
PYH2_k127_9049481_8 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 251.0
PYH2_k127_9049481_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001613 240.0
PYH2_k127_9055040_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 4.4e-323 1000.0
PYH2_k127_9055040_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 514.0
PYH2_k127_9055040_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000002585 114.0
PYH2_k127_9070037_0 Belongs to the IlvD Edd family K22186 - 4.2.1.82 0.0 1064.0
PYH2_k127_9070037_1 Pyridoxal-phosphate dependent enzyme K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 583.0
PYH2_k127_9070037_2 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 470.0
PYH2_k127_9070037_3 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 387.0
PYH2_k127_9070037_4 - - - - 0.0000000000000000000000000000000000000000000000000000000001331 211.0
PYH2_k127_9070037_5 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.000000000000000000000000000000000000000000000000003335 184.0
PYH2_k127_9070037_6 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000001154 109.0
PYH2_k127_9070407_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 496.0
PYH2_k127_9070407_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 368.0
PYH2_k127_9070407_2 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 356.0
PYH2_k127_9070407_3 Flotillin K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000005128 136.0
PYH2_k127_9116818_0 AsmA family K07289,K07290 - - 0.0000000000000000000000000000007707 132.0
PYH2_k127_9116818_1 - - - - 0.0000007522 57.0
PYH2_k127_9165107_0 3-isopropylmalate dehydratase large subunit K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 486.0
PYH2_k127_9165107_1 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 370.0
PYH2_k127_917613_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 2.023e-237 742.0
PYH2_k127_917613_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 403.0
PYH2_k127_917613_2 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 299.0
PYH2_k127_917613_3 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008166 266.0
PYH2_k127_917613_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000005565 55.0
PYH2_k127_920106_0 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 477.0
PYH2_k127_920106_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 352.0
PYH2_k127_920106_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 325.0
PYH2_k127_920106_3 - - - - 0.0000000000156 71.0
PYH2_k127_920106_4 - - - - 0.00000000004365 66.0
PYH2_k127_920106_5 Putative transposase - - - 0.00000005854 55.0
PYH2_k127_920106_7 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000003396 49.0
PYH2_k127_920106_8 - - - - 0.0004845 45.0
PYH2_k127_9253345_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 510.0
PYH2_k127_9253345_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 492.0
PYH2_k127_9253345_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000008072 241.0
PYH2_k127_9253345_3 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000001022 216.0
PYH2_k127_9253345_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000002707 199.0
PYH2_k127_9265619_0 Dehydrogenase K00382 - 1.8.1.4 1.908e-283 875.0
PYH2_k127_9268224_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 572.0
PYH2_k127_9268224_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 501.0
PYH2_k127_9268224_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 472.0
PYH2_k127_9268224_3 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000004826 213.0
PYH2_k127_9268224_4 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000005392 198.0
PYH2_k127_9268224_5 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000003396 201.0
PYH2_k127_9268224_6 - - - - 0.000000003662 60.0
PYH2_k127_9268224_7 Penicillin amidase K01434 - 3.5.1.11 0.00000008406 56.0
PYH2_k127_9268816_0 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 306.0
PYH2_k127_9268816_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000003368 199.0
PYH2_k127_9275039_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 601.0
PYH2_k127_9275039_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 479.0
PYH2_k127_9275039_2 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 468.0
PYH2_k127_9295458_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 545.0
PYH2_k127_9295458_1 coenzyme F390 synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 513.0
PYH2_k127_946184_0 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 433.0
PYH2_k127_946184_1 molybdenum cofactor K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 325.0
PYH2_k127_946184_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 282.0
PYH2_k127_946184_3 Belongs to the UPF0307 family K09889 - - 0.00000000000000000006566 92.0
PYH2_k127_947750_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.16e-299 921.0
PYH2_k127_947750_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004478 280.0
PYH2_k127_961317_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.155e-271 842.0
PYH2_k127_961317_1 Adenylosuccinate lyase C-terminus K01857 - 5.5.1.2 1.987e-244 760.0
PYH2_k127_961317_2 CoA-transferase family III - - - 1.154e-215 674.0
PYH2_k127_961317_3 PFAM conserved K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 529.0
PYH2_k127_961317_4 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 511.0
PYH2_k127_961317_5 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 476.0
PYH2_k127_961317_6 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 305.0
PYH2_k127_961317_7 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000000000000000000000000000000000000000000000000001169 237.0
PYH2_k127_961317_8 - - - - 0.0000000000000000000000000000000000001158 157.0
PYH2_k127_961317_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000004013 72.0
PYH2_k127_979851_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0 1017.0
PYH2_k127_979851_1 Fe-S oxidoreductase K21834 - - 6.84e-227 723.0
PYH2_k127_979851_10 protein conserved in bacteria K09800 - - 0.000000000003312 67.0
PYH2_k127_979851_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 543.0
PYH2_k127_979851_3 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007112 269.0
PYH2_k127_979851_4 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004018 260.0
PYH2_k127_979851_5 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001204 251.0
PYH2_k127_979851_6 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000003888 134.0
PYH2_k127_979851_7 Glycine-zipper domain - - - 0.000000000000000000000000000006417 135.0
PYH2_k127_979851_8 - - - - 0.000000000000000000000005214 109.0
PYH2_k127_979851_9 SnoaL-like domain - - - 0.000000000000005524 83.0