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Overview

ID MAG03229
Name PYH3_bin.36
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order Dehalococcoidales
Family Fen-1064
Genus JAURWL01
Species
Assembly information
Completeness (%) 91.38
Contamination (%) 3.97
GC content (%) 52.0
N50 (bp) 12,620
Genome size (bp) 1,994,365

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1946

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_100044_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 9.07e-219 683.0
PYH3_k127_100044_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 488.0
PYH3_k127_100044_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000003917 205.0
PYH3_k127_100044_11 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000006669 177.0
PYH3_k127_100044_12 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000005091 136.0
PYH3_k127_100044_14 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000002066 82.0
PYH3_k127_100044_15 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000001191 70.0
PYH3_k127_100044_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 466.0
PYH3_k127_100044_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 425.0
PYH3_k127_100044_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 332.0
PYH3_k127_100044_5 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006349 284.0
PYH3_k127_100044_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001138 279.0
PYH3_k127_100044_7 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 268.0
PYH3_k127_100044_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006501 254.0
PYH3_k127_100044_9 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
PYH3_k127_102008_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 359.0
PYH3_k127_102008_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000001353 229.0
PYH3_k127_102008_2 - - - - 0.00000000000000388 82.0
PYH3_k127_102008_3 helix_turn_helix, Lux Regulon - - - 0.0000000000002827 76.0
PYH3_k127_102008_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.000000000003697 68.0
PYH3_k127_1020347_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000006084 246.0
PYH3_k127_1020347_1 heat shock protein DnaJ K05516 - - 0.000000000000001032 83.0
PYH3_k127_1020347_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000005406 57.0
PYH3_k127_1074453_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000181 251.0
PYH3_k127_1074453_1 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000001155 216.0
PYH3_k127_1074453_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000003337 141.0
PYH3_k127_1162035_0 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008076 281.0
PYH3_k127_1162035_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009501 271.0
PYH3_k127_1162035_2 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000002458 259.0
PYH3_k127_1162035_3 Phosphotriesterase K07048 - - 0.000000000000000000000000000000000000000000001818 174.0
PYH3_k127_1162035_4 translation release factor activity - - - 0.00000008338 58.0
PYH3_k127_1184936_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.615e-314 972.0
PYH3_k127_1184936_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 3.893e-296 935.0
PYH3_k127_1184936_10 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 444.0
PYH3_k127_1184936_11 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 395.0
PYH3_k127_1184936_12 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 371.0
PYH3_k127_1184936_13 Iron-containing alcohol dehydrogenase K00001,K04072 - 1.1.1.1,1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 365.0
PYH3_k127_1184936_14 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 328.0
PYH3_k127_1184936_15 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 313.0
PYH3_k127_1184936_16 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 307.0
PYH3_k127_1184936_17 TIGRFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001881 280.0
PYH3_k127_1184936_18 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004978 267.0
PYH3_k127_1184936_19 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001145 259.0
PYH3_k127_1184936_2 Domain of unknown function (DUF3536) - - - 9.569e-267 843.0
PYH3_k127_1184936_20 efflux protein, MATE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001597 267.0
PYH3_k127_1184936_21 acetoacetate decarboxylase activity K01574 - 4.1.1.4 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
PYH3_k127_1184936_22 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000001523 211.0
PYH3_k127_1184936_23 ACT domain - - - 0.00000000000000000000000000000000000000000000000000002806 192.0
PYH3_k127_1184936_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000001741 179.0
PYH3_k127_1184936_25 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000003471 184.0
PYH3_k127_1184936_26 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000002257 123.0
PYH3_k127_1184936_27 PFAM Methylated-DNA- protein -cysteine K07443 - - 0.000000000000000000000000001151 115.0
PYH3_k127_1184936_28 Sugar (and other) transporter - - - 0.000000000000000000000005599 115.0
PYH3_k127_1184936_29 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000005313 75.0
PYH3_k127_1184936_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.355e-243 769.0
PYH3_k127_1184936_31 - - - - 0.0000005566 61.0
PYH3_k127_1184936_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.507e-231 741.0
PYH3_k127_1184936_5 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 599.0
PYH3_k127_1184936_6 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 584.0
PYH3_k127_1184936_7 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 470.0
PYH3_k127_1184936_8 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 452.0
PYH3_k127_1184936_9 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 442.0
PYH3_k127_1289490_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.94e-252 797.0
PYH3_k127_1289490_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006905 274.0
PYH3_k127_1289490_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000001191 164.0
PYH3_k127_1323555_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.457e-299 932.0
PYH3_k127_1323555_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.421e-294 919.0
PYH3_k127_1323555_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 541.0
PYH3_k127_1323555_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 288.0
PYH3_k127_1323555_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000519 262.0
PYH3_k127_1323555_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000002365 178.0
PYH3_k127_1323555_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000151 172.0
PYH3_k127_1323555_7 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000005361 167.0
PYH3_k127_1323555_8 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000001244 80.0
PYH3_k127_1326789_0 nitronate monooxygenase activity K00088,K00459 - 1.1.1.205,1.13.12.16 3.479e-293 905.0
PYH3_k127_1326789_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 4.381e-229 734.0
PYH3_k127_1326789_10 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 449.0
PYH3_k127_1326789_11 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 420.0
PYH3_k127_1326789_12 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 407.0
PYH3_k127_1326789_13 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 386.0
PYH3_k127_1326789_14 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 380.0
PYH3_k127_1326789_15 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 374.0
PYH3_k127_1326789_16 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 370.0
PYH3_k127_1326789_17 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 363.0
PYH3_k127_1326789_18 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 356.0
PYH3_k127_1326789_19 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 351.0
PYH3_k127_1326789_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.49e-226 714.0
PYH3_k127_1326789_20 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 349.0
PYH3_k127_1326789_21 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 337.0
PYH3_k127_1326789_22 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 338.0
PYH3_k127_1326789_23 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 343.0
PYH3_k127_1326789_24 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 333.0
PYH3_k127_1326789_25 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 331.0
PYH3_k127_1326789_26 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 324.0
PYH3_k127_1326789_27 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 320.0
PYH3_k127_1326789_28 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 299.0
PYH3_k127_1326789_29 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004164 271.0
PYH3_k127_1326789_3 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 5.461e-222 700.0
PYH3_k127_1326789_30 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001111 261.0
PYH3_k127_1326789_31 calcium proton exchanger K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001407 270.0
PYH3_k127_1326789_32 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000007771 225.0
PYH3_k127_1326789_33 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000716 222.0
PYH3_k127_1326789_34 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000001853 216.0
PYH3_k127_1326789_35 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000004333 218.0
PYH3_k127_1326789_36 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000001229 206.0
PYH3_k127_1326789_37 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000002691 205.0
PYH3_k127_1326789_38 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000002224 189.0
PYH3_k127_1326789_39 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000001081 173.0
PYH3_k127_1326789_4 Domain of unknown function (DUF4070) - - - 3.594e-201 638.0
PYH3_k127_1326789_40 Protein of unknown function (DUF2889) K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000006038 167.0
PYH3_k127_1326789_41 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000838 145.0
PYH3_k127_1326789_42 CoA binding domain K06929 - - 0.000000000000000000000000000000000009102 139.0
PYH3_k127_1326789_43 PFAM Transglutaminase-like - - - 0.000000000000000000000000000000005771 135.0
PYH3_k127_1326789_44 SNARE associated Golgi protein - - - 0.000000000000000000000000000001362 129.0
PYH3_k127_1326789_45 Protease prsW family - - - 0.0000000000000000000000000000081 130.0
PYH3_k127_1326789_46 - - - - 0.00000000000000000000000002253 109.0
PYH3_k127_1326789_47 Hypothetical methyltransferase - - - 0.0000000000000000000001808 105.0
PYH3_k127_1326789_48 RDD family - - - 0.00000000000000000009483 97.0
PYH3_k127_1326789_49 - - - - 0.00000000000000002978 91.0
PYH3_k127_1326789_5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.499e-195 624.0
PYH3_k127_1326789_50 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000004062 80.0
PYH3_k127_1326789_51 - - - - 0.000000000000239 75.0
PYH3_k127_1326789_52 Antibiotic biosynthesis monooxygenase - - - 0.000000000006527 69.0
PYH3_k127_1326789_53 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000001416 77.0
PYH3_k127_1326789_54 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000006241 59.0
PYH3_k127_1326789_55 - - - - 0.0000166 49.0
PYH3_k127_1326789_6 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 569.0
PYH3_k127_1326789_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 542.0
PYH3_k127_1326789_8 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 491.0
PYH3_k127_1326789_9 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 466.0
PYH3_k127_1366180_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 2.84e-200 629.0
PYH3_k127_1366180_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 359.0
PYH3_k127_1366180_10 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000005048 171.0
PYH3_k127_1366180_11 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000005352 149.0
PYH3_k127_1366180_12 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000002596 133.0
PYH3_k127_1366180_13 PFAM glutaredoxin - - - 0.00000000000000000000000001748 113.0
PYH3_k127_1366180_14 AAA domain - - - 0.000000000000000000003165 102.0
PYH3_k127_1366180_15 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000001935 74.0
PYH3_k127_1366180_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 334.0
PYH3_k127_1366180_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
PYH3_k127_1366180_4 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 286.0
PYH3_k127_1366180_5 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001506 285.0
PYH3_k127_1366180_6 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000001358 236.0
PYH3_k127_1366180_7 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005713 230.0
PYH3_k127_1366180_8 NIL - - - 0.0000000000000000000000000000000000000000000000000000000018 202.0
PYH3_k127_1366180_9 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000002426 214.0
PYH3_k127_1376370_0 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 308.0
PYH3_k127_1376370_1 Beta-lactamase - - - 0.0000000000000000000001257 107.0
PYH3_k127_1376370_2 Lrp/AsnC ligand binding domain - - - 0.00000000000000003544 83.0
PYH3_k127_1395842_0 DNA ligase K01971 - 6.5.1.1 4.501e-250 800.0
PYH3_k127_1395842_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 341.0
PYH3_k127_1395842_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000005194 193.0
PYH3_k127_1395842_3 Mate efflux family protein K03327 - - 0.00000000000000000001478 100.0
PYH3_k127_1395842_4 Glycosyltransferase family 87 - - - 0.0000000000000000008877 99.0
PYH3_k127_1395842_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000807 67.0
PYH3_k127_1412146_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1624.0
PYH3_k127_1412146_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 514.0
PYH3_k127_1412146_10 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000002706 117.0
PYH3_k127_1412146_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000537 93.0
PYH3_k127_1412146_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 299.0
PYH3_k127_1412146_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 299.0
PYH3_k127_1412146_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000186 246.0
PYH3_k127_1412146_5 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000849 199.0
PYH3_k127_1412146_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000001288 177.0
PYH3_k127_1412146_8 KR domain - - - 0.000000000000000000000000000000003602 139.0
PYH3_k127_1412146_9 TAP-like protein - - - 0.0000000000000000000000000001442 125.0
PYH3_k127_1516928_0 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 464.0
PYH3_k127_1516928_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000004435 125.0
PYH3_k127_1516928_2 Type II/IV secretion system protein K02669 - - 0.00000000000000002244 85.0
PYH3_k127_1516928_3 Probable zinc-ribbon domain - - - 0.00000000000001017 76.0
PYH3_k127_15177_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 542.0
PYH3_k127_15177_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 478.0
PYH3_k127_15177_10 Transposase K07497 - - 0.000000000000000000000000008056 110.0
PYH3_k127_15177_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000539 94.0
PYH3_k127_15177_12 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000001791 94.0
PYH3_k127_15177_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000269 69.0
PYH3_k127_15177_14 Cyclic nucleotide-monophosphate binding domain - - - 0.0000004448 58.0
PYH3_k127_15177_15 LacY proton/sugar symporter - - - 0.0000639 48.0
PYH3_k127_15177_16 helix_turn_helix, Lux Regulon - - - 0.00007607 53.0
PYH3_k127_15177_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 389.0
PYH3_k127_15177_3 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 312.0
PYH3_k127_15177_4 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 264.0
PYH3_k127_15177_5 helix_turn_helix, Lux Regulon K11618 - - 0.00000000000000000000000000000000000000000000000000000000000001726 222.0
PYH3_k127_15177_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000007797 217.0
PYH3_k127_15177_7 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000001691 201.0
PYH3_k127_15177_8 Protein of unknown function (DUF402) K09145 - - 0.0000000000000000000000000000000000004223 147.0
PYH3_k127_15177_9 Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - 0.0000000000000000000000000000000005671 147.0
PYH3_k127_1580423_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 8.149e-309 971.0
PYH3_k127_1580423_1 Domain of unknown function (DUF4131) K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 550.0
PYH3_k127_1580423_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001062 286.0
PYH3_k127_1580423_3 COG2015, Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009295 266.0
PYH3_k127_1580423_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000006263 181.0
PYH3_k127_1580423_5 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000001023 116.0
PYH3_k127_1580423_6 RDD family - - - 0.000000000001872 67.0
PYH3_k127_1582293_0 Aromatic ring hydroxylase K14534 - 4.2.1.120,5.3.3.3 1.318e-205 652.0
PYH3_k127_1582293_1 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 466.0
PYH3_k127_1582293_2 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 460.0
PYH3_k127_1582293_3 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000006534 197.0
PYH3_k127_1583729_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 6.231e-210 677.0
PYH3_k127_1583729_1 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 4.039e-198 637.0
PYH3_k127_1583729_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000004893 214.0
PYH3_k127_1583729_3 COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases K00008 - 1.1.1.14 0.000000000000000000000000000000001088 144.0
PYH3_k127_1583729_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000001101 82.0
PYH3_k127_1596247_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 473.0
PYH3_k127_1596247_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000001181 243.0
PYH3_k127_1596247_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000002197 186.0
PYH3_k127_1596247_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000003279 175.0
PYH3_k127_1596247_4 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000008391 153.0
PYH3_k127_1596247_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000003701 69.0
PYH3_k127_1596247_6 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000002205 50.0
PYH3_k127_1619375_0 Ferrous iron transport protein B K04759 - - 1.181e-244 771.0
PYH3_k127_1619375_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 353.0
PYH3_k127_1619375_2 DeoC/LacD family aldolase K01635 - 4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 338.0
PYH3_k127_1619375_3 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 291.0
PYH3_k127_1619375_4 Rhodanese Homology Domain - - - 0.000000000000000000000000000000003941 133.0
PYH3_k127_1619375_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000005569 61.0
PYH3_k127_1619375_7 Protein of unknown function (DUF664) - - - 0.0003415 46.0
PYH3_k127_1622984_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1157.0
PYH3_k127_1622984_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000004339 109.0
PYH3_k127_1622984_2 Regulatory protein, FmdB family - - - 0.000009161 49.0
PYH3_k127_1697701_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1170.0
PYH3_k127_1697701_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 4.499e-202 643.0
PYH3_k127_1697701_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000008376 199.0
PYH3_k127_1697701_11 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000005347 189.0
PYH3_k127_1697701_12 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000009682 187.0
PYH3_k127_1697701_13 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000009493 170.0
PYH3_k127_1697701_14 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000001291 173.0
PYH3_k127_1697701_15 NUDIX domain - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000000000000009521 151.0
PYH3_k127_1697701_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000004251 140.0
PYH3_k127_1697701_17 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000208 151.0
PYH3_k127_1697701_18 Serine aminopeptidase, S33 - - - 0.000000000000000000000000006299 121.0
PYH3_k127_1697701_19 PFAM SpoVT AbrB domain protein K07172 - - 0.000000000000000000000000008245 115.0
PYH3_k127_1697701_2 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 494.0
PYH3_k127_1697701_20 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000008757 102.0
PYH3_k127_1697701_21 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000009509 93.0
PYH3_k127_1697701_22 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000004824 86.0
PYH3_k127_1697701_23 - - - - 0.000000000000000521 88.0
PYH3_k127_1697701_24 COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000002092 72.0
PYH3_k127_1697701_25 cellular response to starvation - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000415 70.0
PYH3_k127_1697701_26 - - - - 0.000002199 53.0
PYH3_k127_1697701_27 - - - - 0.0003504 43.0
PYH3_k127_1697701_3 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 369.0
PYH3_k127_1697701_4 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006876 278.0
PYH3_k127_1697701_5 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002081 261.0
PYH3_k127_1697701_6 efflux protein, MATE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001356 256.0
PYH3_k127_1697701_7 efflux protein, MATE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001424 247.0
PYH3_k127_1697701_8 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000001018 211.0
PYH3_k127_1697701_9 Mate efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000001791 218.0
PYH3_k127_171535_0 Radical SAM N-terminal - - - 4.715e-274 852.0
PYH3_k127_171535_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.066e-257 801.0
PYH3_k127_171535_10 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000003966 128.0
PYH3_k127_171535_11 PFAM Nitroreductase - - - 0.000000000000000000000000007143 117.0
PYH3_k127_171535_12 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.0000000000000000001466 96.0
PYH3_k127_171535_13 regulatory protein, FmdB family - - - 0.0000000000000000188 84.0
PYH3_k127_171535_14 Regulatory protein, FmdB family - - - 0.00000009682 56.0
PYH3_k127_171535_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 617.0
PYH3_k127_171535_3 Elongation factor G C-terminus K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 393.0
PYH3_k127_171535_4 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006588 282.0
PYH3_k127_171535_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002704 253.0
PYH3_k127_171535_6 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000008103 229.0
PYH3_k127_171535_7 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000008709 192.0
PYH3_k127_171535_8 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 - - 0.000000000000000000000000000000000000000000000005194 176.0
PYH3_k127_171535_9 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000006578 140.0
PYH3_k127_1721053_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 1.072e-270 848.0
PYH3_k127_1721053_1 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.0000000000000000000000000000000000002566 145.0
PYH3_k127_1721053_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000001768 146.0
PYH3_k127_1737265_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.853e-319 1002.0
PYH3_k127_1737265_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 3.239e-211 664.0
PYH3_k127_1737265_11 methyltransferase K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000002829 214.0
PYH3_k127_1737265_12 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000003714 143.0
PYH3_k127_1737265_13 spore germination K03605 - - 0.000000000000000000000000000000006928 135.0
PYH3_k127_1737265_14 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000004527 121.0
PYH3_k127_1737265_15 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000001352 118.0
PYH3_k127_1737265_16 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000001129 93.0
PYH3_k127_1737265_17 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.0000000000000004077 78.0
PYH3_k127_1737265_18 PFAM Cyclic nucleotide-binding domain - - - 0.00000007449 60.0
PYH3_k127_1737265_19 ABC transporter substrate-binding protein K02035 - - 0.0000002995 57.0
PYH3_k127_1737265_2 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 1.131e-202 640.0
PYH3_k127_1737265_20 PFAM Integrase catalytic region K07497 - - 0.00007062 45.0
PYH3_k127_1737265_21 Domain of unknown function (DUF4190) - - - 0.0008535 47.0
PYH3_k127_1737265_3 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 602.0
PYH3_k127_1737265_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 544.0
PYH3_k127_1737265_5 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 535.0
PYH3_k127_1737265_6 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 509.0
PYH3_k127_1737265_7 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 390.0
PYH3_k127_1737265_8 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 297.0
PYH3_k127_1737265_9 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004911 280.0
PYH3_k127_1780154_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1069.0
PYH3_k127_1780154_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 451.0
PYH3_k127_1780154_10 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.00000000000000000381 84.0
PYH3_k127_1780154_11 Unextendable partial coding region - - - 0.0000000000000003361 81.0
PYH3_k127_1780154_12 PFAM Biotin lipoyl attachment - - - 0.0000000000000474 75.0
PYH3_k127_1780154_13 - - - - 0.0000000000002911 72.0
PYH3_k127_1780154_14 COG NOG38524 non supervised orthologous group - - - 0.000000000006527 69.0
PYH3_k127_1780154_15 - - - - 0.00000000002823 68.0
PYH3_k127_1780154_16 COG NOG15344 non supervised orthologous group - - - 0.00000000004734 63.0
PYH3_k127_1780154_18 - - - - 0.00009202 45.0
PYH3_k127_1780154_2 PFAM Acyl-CoA dehydrogenase K00248,K22430 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 431.0
PYH3_k127_1780154_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000009202 217.0
PYH3_k127_1780154_4 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA - - - 0.000000000000000000000000000000000000000000000000000000006484 208.0
PYH3_k127_1780154_5 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000007164 142.0
PYH3_k127_1780154_6 - - - - 0.000000000000000000000000000002957 119.0
PYH3_k127_1780154_7 GYD domain - - - 0.0000000000000000000000000009612 115.0
PYH3_k127_1780154_8 - - - - 0.00000000000000000000007406 98.0
PYH3_k127_1780154_9 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000008676 95.0
PYH3_k127_181824_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 1.389e-273 850.0
PYH3_k127_181824_1 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 614.0
PYH3_k127_181824_2 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 408.0
PYH3_k127_181824_3 PFAM Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003736 263.0
PYH3_k127_181824_4 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002965 263.0
PYH3_k127_181824_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000002323 252.0
PYH3_k127_1839239_0 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 518.0
PYH3_k127_1839239_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 338.0
PYH3_k127_1839239_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000003259 261.0
PYH3_k127_1839239_3 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000001628 236.0
PYH3_k127_1953305_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 443.0
PYH3_k127_1953305_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 381.0
PYH3_k127_1953305_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 342.0
PYH3_k127_1953305_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 301.0
PYH3_k127_1953305_4 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 258.0
PYH3_k127_1953305_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000001726 137.0
PYH3_k127_1953305_6 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000002774 125.0
PYH3_k127_1953305_7 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000001292 98.0
PYH3_k127_1953305_8 - - - - 0.00009437 51.0
PYH3_k127_195468_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 396.0
PYH3_k127_195468_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
PYH3_k127_195468_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000003149 189.0
PYH3_k127_195468_3 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000001083 114.0
PYH3_k127_195468_4 - - - - 0.0000000000000000006569 97.0
PYH3_k127_195468_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000503 70.0
PYH3_k127_199415_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1038.0
PYH3_k127_199415_1 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 7.948e-243 760.0
PYH3_k127_199415_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 346.0
PYH3_k127_199415_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 315.0
PYH3_k127_199415_12 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 306.0
PYH3_k127_199415_13 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000417 275.0
PYH3_k127_199415_14 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
PYH3_k127_199415_15 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004875 248.0
PYH3_k127_199415_16 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
PYH3_k127_199415_17 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000002611 193.0
PYH3_k127_199415_18 MatE - - - 0.0000000000000000000000000000000000000000000000000001635 199.0
PYH3_k127_199415_19 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000102 199.0
PYH3_k127_199415_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 604.0
PYH3_k127_199415_20 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000006077 186.0
PYH3_k127_199415_21 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000005196 172.0
PYH3_k127_199415_22 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000007314 171.0
PYH3_k127_199415_23 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000006312 119.0
PYH3_k127_199415_24 tetratricopeptide repeat - - - 0.000000000000000000000005503 112.0
PYH3_k127_199415_25 LamG domain protein jellyroll fold domain protein - - - 0.00000000002955 71.0
PYH3_k127_199415_26 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000004708 74.0
PYH3_k127_199415_27 - - - - 0.0000000006944 63.0
PYH3_k127_199415_28 COG3291 FOG PKD repeat - - - 0.0001465 53.0
PYH3_k127_199415_29 COG NOG16874 non supervised orthologous group - - - 0.0001486 49.0
PYH3_k127_199415_3 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 588.0
PYH3_k127_199415_4 ABC transporter, transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 558.0
PYH3_k127_199415_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 512.0
PYH3_k127_199415_6 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 447.0
PYH3_k127_199415_7 Belongs to the ABC transporter superfamily K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 434.0
PYH3_k127_199415_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 436.0
PYH3_k127_199415_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 355.0
PYH3_k127_2025355_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.298e-254 798.0
PYH3_k127_2025355_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003019 266.0
PYH3_k127_2082344_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 295.0
PYH3_k127_2082344_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
PYH3_k127_2082344_2 Transcriptional regulator - - - 0.00000000000000000006359 96.0
PYH3_k127_2082344_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04079 - - 0.0000008365 59.0
PYH3_k127_2106765_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 349.0
PYH3_k127_2106765_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 331.0
PYH3_k127_2106765_2 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000002221 237.0
PYH3_k127_2106765_3 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000005778 211.0
PYH3_k127_2106765_4 coenzyme A transferase K01031 - 2.8.3.6 0.000000000000000000000000000000000000005781 156.0
PYH3_k127_2106765_5 PFAM regulatory protein TetR - - - 0.000000000000000000000000000001068 129.0
PYH3_k127_2106765_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000001733 117.0
PYH3_k127_2106765_7 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000009857 105.0
PYH3_k127_2106765_8 PFAM CoA-transferase family III - - - 0.00000000005533 64.0
PYH3_k127_210892_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 7.858e-270 853.0
PYH3_k127_210892_1 Dak1_2 K07030 - - 5.829e-210 665.0
PYH3_k127_210892_10 Ribosomal L28 family K02902 - - 0.0000000000000000000003197 97.0
PYH3_k127_210892_11 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000003223 70.0
PYH3_k127_210892_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 558.0
PYH3_k127_210892_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 523.0
PYH3_k127_210892_4 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 512.0
PYH3_k127_210892_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 394.0
PYH3_k127_210892_6 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 291.0
PYH3_k127_210892_7 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002734 276.0
PYH3_k127_210892_8 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002884 261.0
PYH3_k127_210892_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000001643 241.0
PYH3_k127_2134700_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1314.0
PYH3_k127_2134700_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1215.0
PYH3_k127_2134700_10 KH domain K06346 - - 0.00000000000000000000000000000000000000000000000143 185.0
PYH3_k127_2134700_11 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000003038 177.0
PYH3_k127_2134700_12 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000002434 149.0
PYH3_k127_2134700_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000005864 116.0
PYH3_k127_2134700_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000005108 111.0
PYH3_k127_2134700_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000002863 96.0
PYH3_k127_2134700_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000008261 96.0
PYH3_k127_2134700_17 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001237 77.0
PYH3_k127_2134700_18 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001036 75.0
PYH3_k127_2134700_2 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 587.0
PYH3_k127_2134700_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 527.0
PYH3_k127_2134700_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 337.0
PYH3_k127_2134700_5 60Kd inner membrane protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000926 271.0
PYH3_k127_2134700_6 Tetratricopeptide repeat K12600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003595 259.0
PYH3_k127_2134700_7 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000002737 252.0
PYH3_k127_2134700_8 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003909 252.0
PYH3_k127_2134700_9 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000001375 195.0
PYH3_k127_235040_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 604.0
PYH3_k127_235040_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 516.0
PYH3_k127_235040_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
PYH3_k127_235040_3 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 374.0
PYH3_k127_235040_4 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001431 244.0
PYH3_k127_235040_5 PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000001868 160.0
PYH3_k127_235040_6 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000189 149.0
PYH3_k127_235040_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000003067 119.0
PYH3_k127_235040_8 AAA domain K07028 - - 0.00000000000392 75.0
PYH3_k127_2455689_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 438.0
PYH3_k127_2455689_1 acyl-CoA transferases carnitine dehydratase K08298 GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006579,GO:0006807,GO:0008150,GO:0008152,GO:0008735,GO:0009056,GO:0009437,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0042219,GO:0042413,GO:0044237,GO:0044248,GO:0044270,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 2.8.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 424.0
PYH3_k127_2455689_2 Belongs to the HpcH HpaI aldolase family K01644 GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0071704 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000002153 220.0
PYH3_k127_2455689_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000004086 179.0
PYH3_k127_2455689_4 MmgE/PrpD family - - - 0.00000000000000000000000000000000004394 141.0
PYH3_k127_2475486_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 376.0
PYH3_k127_2475486_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 330.0
PYH3_k127_2475486_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000002003 258.0
PYH3_k127_2475486_3 Transposase K07497 - - 0.000000000000000000000000000000000921 131.0
PYH3_k127_2475486_4 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000107 97.0
PYH3_k127_2475486_6 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282,K13419 - 2.7.11.1 0.0000000000593 68.0
PYH3_k127_2488923_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 339.0
PYH3_k127_2488923_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000003257 200.0
PYH3_k127_2488923_2 MaoC like domain - - - 0.00000000000000000000000000000000000006599 146.0
PYH3_k127_2488923_3 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000286 116.0
PYH3_k127_2488923_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000007478 58.0
PYH3_k127_2488923_5 ABC-2 type transporter K01992 - - 0.000000008057 58.0
PYH3_k127_2510154_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 458.0
PYH3_k127_2510154_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 434.0
PYH3_k127_2510154_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000006991 154.0
PYH3_k127_2510154_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000001059 136.0
PYH3_k127_2510154_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 376.0
PYH3_k127_2510154_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 350.0
PYH3_k127_2510154_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 313.0
PYH3_k127_2510154_5 Mo-molybdopterin cofactor metabolic process K02379,K03750,K03752,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.00000000000000000000000000000000000000000000001259 181.0
PYH3_k127_2510154_6 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000302 175.0
PYH3_k127_2510154_7 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000001959 166.0
PYH3_k127_2510154_8 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.00000000000000000000000000000000000000004346 164.0
PYH3_k127_2510154_9 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000005272 153.0
PYH3_k127_2527454_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 331.0
PYH3_k127_2527454_1 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 314.0
PYH3_k127_2527454_2 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.00000000000000000000000001663 113.0
PYH3_k127_2527454_3 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000001492 104.0
PYH3_k127_2527454_4 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000001235 70.0
PYH3_k127_2537392_0 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002554 284.0
PYH3_k127_2537392_1 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000009515 214.0
PYH3_k127_2537392_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000009977 200.0
PYH3_k127_2537392_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000004346 176.0
PYH3_k127_2537392_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000002621 164.0
PYH3_k127_2537392_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000001146 133.0
PYH3_k127_2537392_6 Arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.00000000000000000000000001335 116.0
PYH3_k127_2537392_7 Thioesterase superfamily protein - - - 0.00004089 48.0
PYH3_k127_2570832_0 - - - - 0.00000000000000000000000000000002206 134.0
PYH3_k127_2570832_1 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000001076 132.0
PYH3_k127_2570832_2 - - - - 0.00000000004488 68.0
PYH3_k127_2570832_3 pathogenesis - - - 0.00000003391 64.0
PYH3_k127_268636_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000001078 207.0
PYH3_k127_268636_1 (ABC) transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000001535 145.0
PYH3_k127_268636_2 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000003451 128.0
PYH3_k127_268636_3 Helix-turn-helix domain - - - 0.0000000000000000000000007696 112.0
PYH3_k127_268636_4 Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000003217 77.0
PYH3_k127_2692442_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 501.0
PYH3_k127_2692442_1 Hydantoinase/oxoprolinase N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 494.0
PYH3_k127_2692442_10 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000008138 171.0
PYH3_k127_2692442_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 473.0
PYH3_k127_2692442_3 PFAM homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000001182 254.0
PYH3_k127_2692442_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000001331 241.0
PYH3_k127_2692442_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000006119 235.0
PYH3_k127_2692442_6 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000007391 239.0
PYH3_k127_2692442_7 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000002458 206.0
PYH3_k127_2692442_8 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000002003 199.0
PYH3_k127_2692442_9 PFAM Vitamin B12 dependent methionine synthase, activation domain - - - 0.00000000000000000000000000000000000000000000000005075 187.0
PYH3_k127_2773144_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 349.0
PYH3_k127_2773144_1 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001122 276.0
PYH3_k127_2773144_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000001486 231.0
PYH3_k127_2773144_3 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000001083 156.0
PYH3_k127_2773144_4 Belongs to the 'phage' integrase family K04763 - - 0.00008333 51.0
PYH3_k127_2776039_0 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000005469 166.0
PYH3_k127_2776039_1 PFAM Phage tail protein (Tail_P2_I) - - - 0.0004424 45.0
PYH3_k127_282957_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1470.0
PYH3_k127_2864159_0 Biotin carboxylase C-terminal domain - - - 0.0 1224.0
PYH3_k127_2864159_1 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 381.0
PYH3_k127_2864159_10 Thioesterase superfamily - - - 0.0000000000000004526 81.0
PYH3_k127_2864159_11 Bacterial transcriptional activator domain - - - 0.00000004487 66.0
PYH3_k127_2864159_12 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000001025 60.0
PYH3_k127_2864159_2 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 365.0
PYH3_k127_2864159_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 341.0
PYH3_k127_2864159_4 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 314.0
PYH3_k127_2864159_5 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000001333 221.0
PYH3_k127_2864159_6 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000005321 188.0
PYH3_k127_2864159_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.000000000000000000000000000000000000000000009127 164.0
PYH3_k127_2864159_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000005113 155.0
PYH3_k127_2864159_9 4Fe-4S ferredoxin iron-sulfur binding domain protein K07307 - - 0.00000000000000000000001713 117.0
PYH3_k127_2868380_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 571.0
PYH3_k127_2868380_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 495.0
PYH3_k127_2868380_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 442.0
PYH3_k127_2868380_3 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 310.0
PYH3_k127_2868380_4 PFAM CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000006364 231.0
PYH3_k127_2868380_5 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000004762 199.0
PYH3_k127_2868380_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001284 174.0
PYH3_k127_2886967_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 317.0
PYH3_k127_2886967_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 297.0
PYH3_k127_2886967_10 ABC-2 family transporter protein - - - 0.000000000000000000000002654 112.0
PYH3_k127_2886967_11 PFAM Electron transfer flavoprotein domain K03522,K22432 - 1.3.1.108 0.000000000000000003351 92.0
PYH3_k127_2886967_2 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008983 286.0
PYH3_k127_2886967_3 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005468 281.0
PYH3_k127_2886967_4 Alpha beta hydrolase K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008076 272.0
PYH3_k127_2886967_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004915 254.0
PYH3_k127_2886967_6 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000003381 243.0
PYH3_k127_2886967_7 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000001198 221.0
PYH3_k127_2886967_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000381 197.0
PYH3_k127_2886967_9 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000002645 139.0
PYH3_k127_293567_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 501.0
PYH3_k127_293567_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 493.0
PYH3_k127_293567_2 Family of unknown function (DUF5343) - - - 0.0000000000000000000518 94.0
PYH3_k127_293567_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000002602 49.0
PYH3_k127_293567_4 - - - - 0.00008558 47.0
PYH3_k127_2937254_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 9.552e-304 939.0
PYH3_k127_2937254_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.158e-268 843.0
PYH3_k127_2937254_10 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 285.0
PYH3_k127_2937254_11 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
PYH3_k127_2937254_12 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
PYH3_k127_2937254_13 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001661 237.0
PYH3_k127_2937254_14 Protein of unknown function (DUF2167) - - - 0.00000000000000000000000000000000000000000000000000000003879 206.0
PYH3_k127_2937254_15 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000009997 199.0
PYH3_k127_2937254_16 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000003075 204.0
PYH3_k127_2937254_17 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000005756 184.0
PYH3_k127_2937254_18 - K07018 - - 0.00000000000000000000000000000000000000000000003817 179.0
PYH3_k127_2937254_19 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000008624 174.0
PYH3_k127_2937254_2 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 559.0
PYH3_k127_2937254_20 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000004154 171.0
PYH3_k127_2937254_21 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000001048 145.0
PYH3_k127_2937254_22 Enoyl-CoA hydratase/isomerase K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000004789 148.0
PYH3_k127_2937254_23 Thioredoxin K03671 - - 0.000000000000000000000000000000000006351 139.0
PYH3_k127_2937254_24 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000005793 100.0
PYH3_k127_2937254_25 helix_turn_helix, mercury resistance - - - 0.000000000003529 68.0
PYH3_k127_2937254_3 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 459.0
PYH3_k127_2937254_4 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 365.0
PYH3_k127_2937254_5 Histidine kinase K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 351.0
PYH3_k127_2937254_6 LacY proton/sugar symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 340.0
PYH3_k127_2937254_7 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
PYH3_k127_2937254_8 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 295.0
PYH3_k127_2937254_9 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 288.0
PYH3_k127_2957117_0 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 538.0
PYH3_k127_2957117_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 449.0
PYH3_k127_2957117_2 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 299.0
PYH3_k127_2957117_3 Carboxylesterase family K03929 - - 0.000007952 49.0
PYH3_k127_2957117_4 Acetyltransferase (GNAT) domain - - - 0.000009185 54.0
PYH3_k127_3010453_0 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000001377 144.0
PYH3_k127_3010453_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000003708 131.0
PYH3_k127_3015172_0 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 308.0
PYH3_k127_3015172_1 Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005394 259.0
PYH3_k127_3015172_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000001088 231.0
PYH3_k127_3015172_3 Domain of unknown function (DUF4382) - - - 0.000003291 59.0
PYH3_k127_3032278_0 AMP-binding enzyme K01897 - 6.2.1.3 6.491e-293 911.0
PYH3_k127_3032278_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 468.0
PYH3_k127_3032278_10 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.00000000000000000000000000000000000000005254 156.0
PYH3_k127_3032278_2 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 457.0
PYH3_k127_3032278_3 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 413.0
PYH3_k127_3032278_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 402.0
PYH3_k127_3032278_5 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 387.0
PYH3_k127_3032278_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001524 291.0
PYH3_k127_3032278_7 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001795 272.0
PYH3_k127_3032278_8 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000007954 244.0
PYH3_k127_3032278_9 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000007258 208.0
PYH3_k127_3184326_0 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate K03340 - 1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 369.0
PYH3_k127_3184326_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000007674 247.0
PYH3_k127_3184326_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000111 232.0
PYH3_k127_3184326_3 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000000189 147.0
PYH3_k127_3184326_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K11329 - - 0.0000000000000000000001362 101.0
PYH3_k127_3271540_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.269e-245 768.0
PYH3_k127_3271540_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.137e-215 680.0
PYH3_k127_3271540_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 460.0
PYH3_k127_3271540_3 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 315.0
PYH3_k127_3271540_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
PYH3_k127_3271540_5 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 308.0
PYH3_k127_3271540_6 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 300.0
PYH3_k127_3271540_7 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000003498 182.0
PYH3_k127_3271540_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000003664 173.0
PYH3_k127_3271540_9 - - - - 0.0000000000000006298 81.0
PYH3_k127_3299539_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.068e-260 812.0
PYH3_k127_3299539_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.746e-198 624.0
PYH3_k127_3299539_10 PFAM Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 320.0
PYH3_k127_3299539_11 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 314.0
PYH3_k127_3299539_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 287.0
PYH3_k127_3299539_13 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007084 286.0
PYH3_k127_3299539_14 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000527 274.0
PYH3_k127_3299539_15 Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 260.0
PYH3_k127_3299539_16 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000009953 243.0
PYH3_k127_3299539_17 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000004072 209.0
PYH3_k127_3299539_18 HAD hydrolase, family IA, variant 1 K07025 - - 0.00000000000000000000000000000000000000000000003909 178.0
PYH3_k127_3299539_19 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000006556 156.0
PYH3_k127_3299539_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 616.0
PYH3_k127_3299539_20 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000001527 117.0
PYH3_k127_3299539_21 Methyltransferase type 11 - - - 0.00000000000000000001047 102.0
PYH3_k127_3299539_22 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000004311 93.0
PYH3_k127_3299539_23 cell adhesion involved in biofilm formation - - - 0.0002895 52.0
PYH3_k127_3299539_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 516.0
PYH3_k127_3299539_4 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 386.0
PYH3_k127_3299539_5 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 367.0
PYH3_k127_3299539_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 363.0
PYH3_k127_3299539_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 352.0
PYH3_k127_3299539_8 4Fe-4S double cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
PYH3_k127_3299539_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 359.0
PYH3_k127_3441817_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 434.0
PYH3_k127_3441817_1 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 336.0
PYH3_k127_3441817_2 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily K02617 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.0000000000000000000000000000000000002542 146.0
PYH3_k127_3441817_3 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000113 111.0
PYH3_k127_3441817_4 TM2 domain - - - 0.000000000000672 73.0
PYH3_k127_348066_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002386 262.0
PYH3_k127_348066_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000002215 260.0
PYH3_k127_348066_2 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000002952 246.0
PYH3_k127_348066_3 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000007644 247.0
PYH3_k127_348066_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000001579 211.0
PYH3_k127_348066_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000001839 183.0
PYH3_k127_348066_6 - - - - 0.000000000000000000000000000000000001657 147.0
PYH3_k127_3638554_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.71e-260 823.0
PYH3_k127_3638554_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000008462 238.0
PYH3_k127_3638554_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000005414 102.0
PYH3_k127_3638554_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000001277 84.0
PYH3_k127_3661322_0 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 466.0
PYH3_k127_3661322_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 436.0
PYH3_k127_3661322_2 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 428.0
PYH3_k127_3661322_3 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 320.0
PYH3_k127_3661322_4 DNA modification repair radical SAM protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 297.0
PYH3_k127_3661322_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 300.0
PYH3_k127_3661322_6 Binding-protein-dependent transport system inner membrane component K15581 - - 0.00000000000000000000000000000000002119 136.0
PYH3_k127_3661322_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000003764 115.0
PYH3_k127_3683938_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 450.0
PYH3_k127_3683938_1 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 377.0
PYH3_k127_3683938_2 hydrogenase large subunit K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002669 255.0
PYH3_k127_3683938_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000006268 232.0
PYH3_k127_3683938_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000005513 179.0
PYH3_k127_3683938_5 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000003417 135.0
PYH3_k127_3683938_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000008918 101.0
PYH3_k127_3684402_0 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 314.0
PYH3_k127_3684402_1 Thioesterase superfamily K02614 - - 0.00000000000000000000000000000000002068 139.0
PYH3_k127_3684402_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000003427 127.0
PYH3_k127_3684402_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000002057 77.0
PYH3_k127_3684402_4 META domain - - - 0.00000000002955 70.0
PYH3_k127_3711780_0 phosphatidylinositol metabolic process K13671 - - 0.00000000000000000000000000000000000004207 158.0
PYH3_k127_3711780_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000005057 128.0
PYH3_k127_3711780_2 Helix-turn-helix domain - - - 0.0000000106 61.0
PYH3_k127_3711780_3 - - - - 0.0000004804 57.0
PYH3_k127_3798585_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.085e-197 627.0
PYH3_k127_3798585_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 591.0
PYH3_k127_3798585_10 AMP binding - - - 0.0000000000000000000000000000001886 129.0
PYH3_k127_3798585_11 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000001374 122.0
PYH3_k127_3798585_12 peptidase U32 - - - 0.00000000000000000000000004012 109.0
PYH3_k127_3798585_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000001737 108.0
PYH3_k127_3798585_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000004278 98.0
PYH3_k127_3798585_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 536.0
PYH3_k127_3798585_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 523.0
PYH3_k127_3798585_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 444.0
PYH3_k127_3798585_5 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 297.0
PYH3_k127_3798585_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000005867 245.0
PYH3_k127_3798585_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000008026 235.0
PYH3_k127_3798585_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000008681 236.0
PYH3_k127_3798585_9 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000006862 222.0
PYH3_k127_3799557_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 4.285e-314 992.0
PYH3_k127_3799557_1 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.967e-210 666.0
PYH3_k127_3799557_2 Molybdopterin oxidoreductase Fe4S4 region K00336,K05299 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 364.0
PYH3_k127_3799557_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 329.0
PYH3_k127_3799557_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 321.0
PYH3_k127_3799557_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000004659 217.0
PYH3_k127_3799557_6 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003137 168.0
PYH3_k127_3799557_7 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000001503 126.0
PYH3_k127_3856287_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004204 263.0
PYH3_k127_3856287_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000005813 96.0
PYH3_k127_3856287_2 PFAM ABC transporter related K01990 - - 0.00000000000000001548 86.0
PYH3_k127_3856287_3 ABC-2 family transporter protein K01992 - - 0.00002564 52.0
PYH3_k127_3921862_0 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 397.0
PYH3_k127_3921862_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 358.0
PYH3_k127_3921862_2 SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 312.0
PYH3_k127_3921862_3 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000002762 213.0
PYH3_k127_3921862_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000001008 211.0
PYH3_k127_3921862_5 PFAM UspA domain protein - - - 0.0005539 47.0
PYH3_k127_3924602_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.574e-195 619.0
PYH3_k127_3924602_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 550.0
PYH3_k127_3924602_10 ABC-type tungstate transport system, periplasmic component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001889 252.0
PYH3_k127_3924602_11 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003775 246.0
PYH3_k127_3924602_13 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000007986 159.0
PYH3_k127_3924602_14 TetR family transcriptional regulator - - - 0.000000000000000000000000003711 119.0
PYH3_k127_3924602_15 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000001465 108.0
PYH3_k127_3924602_16 - - - - 0.000000000000000000009675 93.0
PYH3_k127_3924602_17 Preprotein translocase SecG subunit K03075 - - 0.000000000000000006533 87.0
PYH3_k127_3924602_18 membrane - - - 0.0000000001837 65.0
PYH3_k127_3924602_19 stress-induced mitochondrial fusion - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000008987 62.0
PYH3_k127_3924602_2 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 371.0
PYH3_k127_3924602_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 351.0
PYH3_k127_3924602_4 ATPase activity K02010,K02017,K02019,K02049,K02068,K02071,K06857,K10112 - 3.6.3.29,3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 350.0
PYH3_k127_3924602_5 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
PYH3_k127_3924602_6 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 309.0
PYH3_k127_3924602_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 291.0
PYH3_k127_3924602_8 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 273.0
PYH3_k127_3924602_9 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 263.0
PYH3_k127_3981851_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 1.103e-253 807.0
PYH3_k127_3981851_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 436.0
PYH3_k127_3981851_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 434.0
PYH3_k127_3981851_3 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 407.0
PYH3_k127_3981851_4 Phage integrase family - - - 0.000000000000000000000000000000000000000000006721 177.0
PYH3_k127_3981851_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000001514 106.0
PYH3_k127_4008710_0 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 559.0
PYH3_k127_4008710_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 327.0
PYH3_k127_4008710_2 3-oxoacid CoA-transferase, B subunit K01029 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
PYH3_k127_4008710_3 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01031 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000002264 239.0
PYH3_k127_4008710_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000003182 200.0
PYH3_k127_4008710_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000001042 198.0
PYH3_k127_4008710_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000006817 182.0
PYH3_k127_4008710_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000339 164.0
PYH3_k127_4008710_8 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000001044 133.0
PYH3_k127_4019468_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 467.0
PYH3_k127_4019468_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 380.0
PYH3_k127_4019468_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000001773 235.0
PYH3_k127_4019468_3 Domain of unknown function (DUF4342) - - - 0.0000000002409 65.0
PYH3_k127_4019468_4 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000005438 59.0
PYH3_k127_4019468_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0001668 44.0
PYH3_k127_4068411_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002414 282.0
PYH3_k127_4068411_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009883 273.0
PYH3_k127_4068411_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000001379 184.0
PYH3_k127_4075219_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 402.0
PYH3_k127_4075219_1 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
PYH3_k127_4075219_2 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000005868 209.0
PYH3_k127_4075219_3 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000009198 112.0
PYH3_k127_4167289_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1401.0
PYH3_k127_4167289_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.443e-280 884.0
PYH3_k127_4167289_10 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 349.0
PYH3_k127_4167289_11 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 336.0
PYH3_k127_4167289_12 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 293.0
PYH3_k127_4167289_13 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000004022 259.0
PYH3_k127_4167289_14 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000735 235.0
PYH3_k127_4167289_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
PYH3_k127_4167289_16 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002306 229.0
PYH3_k127_4167289_17 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000000001676 209.0
PYH3_k127_4167289_18 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000007813 207.0
PYH3_k127_4167289_19 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000003852 204.0
PYH3_k127_4167289_2 elongation factor Tu domain 2 protein K02355 - - 4.64e-196 632.0
PYH3_k127_4167289_20 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000008513 188.0
PYH3_k127_4167289_21 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000001822 184.0
PYH3_k127_4167289_22 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000001125 137.0
PYH3_k127_4167289_23 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000002165 137.0
PYH3_k127_4167289_24 MFS_1 like family - - - 0.000000000000000000000000000000000468 151.0
PYH3_k127_4167289_25 -acetyltransferase - - - 0.0000000000000000000000000001005 120.0
PYH3_k127_4167289_26 sulfur carrier activity - - - 0.0000000000000000000000001746 107.0
PYH3_k127_4167289_27 glutaredoxin-like protein, YruB-family - - - 0.000000000000000000002035 94.0
PYH3_k127_4167289_28 - - - - 0.00000000000000004649 83.0
PYH3_k127_4167289_29 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000001418 72.0
PYH3_k127_4167289_3 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 557.0
PYH3_k127_4167289_30 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000006938 64.0
PYH3_k127_4167289_31 - - - - 0.000001012 54.0
PYH3_k127_4167289_32 SNARE associated Golgi protein - - - 0.00001286 48.0
PYH3_k127_4167289_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 486.0
PYH3_k127_4167289_5 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 464.0
PYH3_k127_4167289_6 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 455.0
PYH3_k127_4167289_7 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 449.0
PYH3_k127_4167289_8 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 404.0
PYH3_k127_4167289_9 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 400.0
PYH3_k127_417855_0 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 518.0
PYH3_k127_417855_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 457.0
PYH3_k127_417855_2 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000009395 213.0
PYH3_k127_417855_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000046 149.0
PYH3_k127_4193216_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 1.725e-284 890.0
PYH3_k127_4193216_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 379.0
PYH3_k127_4193216_2 hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000903 221.0
PYH3_k127_4206730_0 regulation of response to stimulus K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 448.0
PYH3_k127_4206730_1 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000003865 205.0
PYH3_k127_4206730_2 Abc transporter K02003 - - 0.00000000000000000000000000000000000001378 147.0
PYH3_k127_4206730_3 TIGRFAM methyltransferase FkbM - - - 0.000000000000000000007831 104.0
PYH3_k127_4206730_4 - - - - 0.000000000000000007542 89.0
PYH3_k127_4206730_5 CAAX protease self-immunity K07052 - - 0.00000000000005947 74.0
PYH3_k127_426105_0 Toxic anion resistance - - - 0.0000000000000000000000000000000000000007171 163.0
PYH3_k127_426105_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000001573 152.0
PYH3_k127_426105_2 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000009449 80.0
PYH3_k127_432758_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 447.0
PYH3_k127_432758_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 301.0
PYH3_k127_432758_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000004606 188.0
PYH3_k127_443013_0 succinate dehydrogenase K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 301.0
PYH3_k127_443013_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
PYH3_k127_443013_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000001895 143.0
PYH3_k127_443013_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000125 68.0
PYH3_k127_4459536_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1107.0
PYH3_k127_4459536_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1020.0
PYH3_k127_4459536_10 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001693 275.0
PYH3_k127_4459536_11 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000002464 244.0
PYH3_k127_4459536_12 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000008251 193.0
PYH3_k127_4459536_13 - - - - 0.0000000000000000000000000000000000000000000000002129 184.0
PYH3_k127_4459536_14 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000007638 136.0
PYH3_k127_4459536_15 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000808 138.0
PYH3_k127_4459536_16 DNA polymerase X family K02347 - - 0.00000000000007882 76.0
PYH3_k127_4459536_17 Ftsk_gamma K03466 - - 0.00008369 49.0
PYH3_k127_4459536_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.425e-244 764.0
PYH3_k127_4459536_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 529.0
PYH3_k127_4459536_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 457.0
PYH3_k127_4459536_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 390.0
PYH3_k127_4459536_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 359.0
PYH3_k127_4459536_7 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 310.0
PYH3_k127_4459536_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 310.0
PYH3_k127_4459536_9 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000006597 279.0
PYH3_k127_4579295_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 374.0
PYH3_k127_4579295_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 350.0
PYH3_k127_4579295_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 329.0
PYH3_k127_4579295_3 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 314.0
PYH3_k127_4579295_4 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002702 276.0
PYH3_k127_4579295_5 short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000111 201.0
PYH3_k127_4579295_6 FCD domain protein - - - 0.000000000000000000000000000002627 128.0
PYH3_k127_4579295_7 PFAM CoA-transferase family III - - - 0.000000000000002445 77.0
PYH3_k127_4579295_8 Metallo-beta-lactamase superfamily K05555 - - 0.000000001312 64.0
PYH3_k127_4623897_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 403.0
PYH3_k127_4623897_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 308.0
PYH3_k127_4623897_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000003269 203.0
PYH3_k127_4623897_11 Cytochrome c3 - - - 0.00000000000000000000000000000000001504 148.0
PYH3_k127_4623897_12 Response regulator receiver K07696 - - 0.0000000000000000000007766 103.0
PYH3_k127_4623897_13 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000001615 76.0
PYH3_k127_4623897_15 Carboxypeptidase regulatory-like domain - - - 0.000009392 54.0
PYH3_k127_4623897_2 Polysulphide reductase K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 294.0
PYH3_k127_4623897_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006221 258.0
PYH3_k127_4623897_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007539 268.0
PYH3_k127_4623897_5 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006143 257.0
PYH3_k127_4623897_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007577 271.0
PYH3_k127_4623897_7 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000001214 235.0
PYH3_k127_4623897_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000002797 213.0
PYH3_k127_4623897_9 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000000000005548 201.0
PYH3_k127_4782394_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 466.0
PYH3_k127_4782394_1 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 415.0
PYH3_k127_4782394_10 Flavodoxin domain - - - 0.00000001867 63.0
PYH3_k127_4782394_11 Protein of unknown function (DUF998) - - - 0.000267 51.0
PYH3_k127_4782394_2 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000009732 269.0
PYH3_k127_4782394_3 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
PYH3_k127_4782394_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000276 251.0
PYH3_k127_4782394_5 basic membrane K07335 - - 0.00000000000000000000000000000000000000000000000000000000000004911 227.0
PYH3_k127_4782394_6 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000001448 222.0
PYH3_k127_4782394_7 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000000000001887 136.0
PYH3_k127_4782394_8 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000000000004425 103.0
PYH3_k127_4782394_9 - - - - 0.000000000000000001937 89.0
PYH3_k127_4788309_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.07e-269 839.0
PYH3_k127_4788309_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.012e-207 654.0
PYH3_k127_4788309_10 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000005206 175.0
PYH3_k127_4788309_11 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000003643 162.0
PYH3_k127_4788309_12 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.00000000000000000000000000000000000000002286 158.0
PYH3_k127_4788309_13 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000002466 150.0
PYH3_k127_4788309_14 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000001293 128.0
PYH3_k127_4788309_15 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.000000000000000000000000000002037 121.0
PYH3_k127_4788309_16 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000005237 128.0
PYH3_k127_4788309_17 dehydratase - - - 0.00000000000000000000001799 103.0
PYH3_k127_4788309_18 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.000000000000000000002242 100.0
PYH3_k127_4788309_19 Belongs to the UPF0434 family - - - 0.0000000001533 62.0
PYH3_k127_4788309_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 547.0
PYH3_k127_4788309_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 479.0
PYH3_k127_4788309_4 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005941 288.0
PYH3_k127_4788309_5 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 255.0
PYH3_k127_4788309_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000001573 225.0
PYH3_k127_4788309_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000001177 213.0
PYH3_k127_4788309_8 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000000000000007623 212.0
PYH3_k127_4788309_9 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000006713 188.0
PYH3_k127_4800822_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 344.0
PYH3_k127_4800822_1 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000007809 204.0
PYH3_k127_4800822_2 pfam nudix - - - 0.00000000000000000000000000000000000002137 149.0
PYH3_k127_4800822_3 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000496 83.0
PYH3_k127_4800822_4 protein conserved in bacteria - - - 0.00001975 47.0
PYH3_k127_4875782_0 AAA-like domain K06915 - - 8.126e-225 709.0
PYH3_k127_4875782_1 NurA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 311.0
PYH3_k127_4875782_2 PFAM HAS barrel domain - - - 0.0000000000000000000000000000000000000000000000000001972 191.0
PYH3_k127_4875782_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000003485 144.0
PYH3_k127_4881725_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 466.0
PYH3_k127_4881725_1 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 464.0
PYH3_k127_4881725_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 280.0
PYH3_k127_4881725_3 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
PYH3_k127_4881725_4 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
PYH3_k127_4881725_5 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000455 203.0
PYH3_k127_4881725_6 Cupin domain protein - - - 0.0000000000000000000000000000000000000001626 152.0
PYH3_k127_4881725_7 - - - - 0.0000000000000000000000000000421 118.0
PYH3_k127_4881725_8 NifU-like domain - - - 0.00000000000000000000000006428 108.0
PYH3_k127_4881725_9 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000001553 110.0
PYH3_k127_4883575_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 455.0
PYH3_k127_4883575_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 421.0
PYH3_k127_4883575_10 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000004627 210.0
PYH3_k127_4883575_11 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000002342 213.0
PYH3_k127_4883575_12 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000002657 198.0
PYH3_k127_4883575_13 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000004832 189.0
PYH3_k127_4883575_14 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000002539 93.0
PYH3_k127_4883575_15 Belongs to the 2H phosphoesterase superfamily. YjcG family - - - 0.00000005014 61.0
PYH3_k127_4883575_16 - - - - 0.00001694 53.0
PYH3_k127_4883575_2 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 415.0
PYH3_k127_4883575_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 414.0
PYH3_k127_4883575_4 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 406.0
PYH3_k127_4883575_5 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 370.0
PYH3_k127_4883575_6 Family of unknown function (DUF438) K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 347.0
PYH3_k127_4883575_7 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 335.0
PYH3_k127_4883575_8 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 287.0
PYH3_k127_4883575_9 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000006537 237.0
PYH3_k127_4886445_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 555.0
PYH3_k127_4886445_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003889 246.0
PYH3_k127_4886445_2 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000001323 226.0
PYH3_k127_4886445_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000003548 194.0
PYH3_k127_4886445_4 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000312 162.0
PYH3_k127_4886445_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000003571 111.0
PYH3_k127_4886445_6 - - - - 0.00000000001318 67.0
PYH3_k127_49923_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003806 272.0
PYH3_k127_49923_1 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002385 243.0
PYH3_k127_49923_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000002099 53.0
PYH3_k127_5033846_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 607.0
PYH3_k127_5033846_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 382.0
PYH3_k127_5033846_2 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 342.0
PYH3_k127_5033846_3 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 311.0
PYH3_k127_5033846_4 Colicin V production protein K03558 - - 0.000000000000000000000000000001825 130.0
PYH3_k127_5033846_5 AMP binding - - - 0.00000000000000000009757 96.0
PYH3_k127_5033846_6 PFAM multi antimicrobial extrusion protein - - - 0.000000000000000001159 91.0
PYH3_k127_5033846_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00003794 56.0
PYH3_k127_5059647_0 Dak1_2 K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 462.0
PYH3_k127_5059647_1 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
PYH3_k127_5059647_2 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000005445 168.0
PYH3_k127_5059647_3 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000004978 135.0
PYH3_k127_5059647_4 methyltransferase K13311,K13326,K21335 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983 2.1.1.234 0.0000002265 54.0
PYH3_k127_5059647_5 Protein of unknown function (DUF998) - - - 0.00002085 55.0
PYH3_k127_5059647_6 PFAM Integrase catalytic region K07497 - - 0.00008963 47.0
PYH3_k127_5059647_7 - - - - 0.0009183 48.0
PYH3_k127_5060238_0 Elongation factor G C-terminus K06207 - - 2.496e-272 850.0
PYH3_k127_5060238_1 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 543.0
PYH3_k127_5060238_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 414.0
PYH3_k127_5060238_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000003968 244.0
PYH3_k127_5060238_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000003904 123.0
PYH3_k127_5063831_0 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 577.0
PYH3_k127_5063831_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 561.0
PYH3_k127_5063831_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001098 251.0
PYH3_k127_5063831_11 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000008442 244.0
PYH3_k127_5063831_12 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000001609 245.0
PYH3_k127_5063831_13 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000916 236.0
PYH3_k127_5063831_14 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000007496 216.0
PYH3_k127_5063831_15 3'-5' exonuclease activity K03547 - - 0.0000000000000000000000000000000542 134.0
PYH3_k127_5063831_16 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000003734 125.0
PYH3_k127_5063831_17 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000001098 82.0
PYH3_k127_5063831_18 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000002346 82.0
PYH3_k127_5063831_19 Peptide ABC transporter substrate-binding protein K02035 - - 0.00002568 49.0
PYH3_k127_5063831_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 552.0
PYH3_k127_5063831_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 462.0
PYH3_k127_5063831_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 334.0
PYH3_k127_5063831_5 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 337.0
PYH3_k127_5063831_6 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 309.0
PYH3_k127_5063831_7 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004168 285.0
PYH3_k127_5063831_8 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
PYH3_k127_5063831_9 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000008162 266.0
PYH3_k127_5081342_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 500.0
PYH3_k127_5081342_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000004329 183.0
PYH3_k127_5081342_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000004313 175.0
PYH3_k127_5081342_3 ethyl tert-butyl ether degradation - - - 0.0000000000000000000008514 98.0
PYH3_k127_5081342_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0003135 50.0
PYH3_k127_5195110_0 AcrB/AcrD/AcrF family K03296 - - 6.843e-218 710.0
PYH3_k127_5195110_1 Aminotransferase class I and II K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 555.0
PYH3_k127_5195110_10 SpoVT / AbrB like domain - - - 0.0000000001449 66.0
PYH3_k127_5195110_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 426.0
PYH3_k127_5195110_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 418.0
PYH3_k127_5195110_4 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 384.0
PYH3_k127_5195110_5 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 302.0
PYH3_k127_5195110_6 COG2015, Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001183 246.0
PYH3_k127_5195110_7 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000002442 211.0
PYH3_k127_5195110_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000001154 178.0
PYH3_k127_5195110_9 RNA recognition motif - - - 0.0000000000000000000000000000001802 126.0
PYH3_k127_5238143_0 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000001028 176.0
PYH3_k127_5238143_1 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000002717 138.0
PYH3_k127_5238143_2 cell adhesion involved in biofilm formation - - - 0.0000000000000000006949 101.0
PYH3_k127_5238143_3 Pkd domain containing protein - - - 0.00000000005356 76.0
PYH3_k127_5253746_0 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 409.0
PYH3_k127_5253746_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 347.0
PYH3_k127_5253746_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 351.0
PYH3_k127_5253746_3 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 286.0
PYH3_k127_5253746_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007483 258.0
PYH3_k127_5253746_5 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000001546 216.0
PYH3_k127_5253746_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000102 173.0
PYH3_k127_5253746_7 PFAM glycine cleavage H-protein - - - 0.0000000000001075 79.0
PYH3_k127_5263488_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 3.62e-280 880.0
PYH3_k127_5263488_1 PFAM AMP-dependent synthetase and ligase K00666 - - 2.359e-213 677.0
PYH3_k127_5263488_10 sequence-specific DNA binding K18830 - - 0.0000000000000000000000000000000000003887 143.0
PYH3_k127_5263488_11 Membrane - - - 0.000000000000000000000007372 110.0
PYH3_k127_5263488_13 - - - - 0.00000000000000000001156 98.0
PYH3_k127_5263488_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000002303 86.0
PYH3_k127_5263488_15 - - - - 0.0000000000000005399 82.0
PYH3_k127_5263488_16 Hint domain - - - 0.0001703 53.0
PYH3_k127_5263488_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 6.241e-195 616.0
PYH3_k127_5263488_3 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 535.0
PYH3_k127_5263488_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 532.0
PYH3_k127_5263488_5 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 385.0
PYH3_k127_5263488_6 Nitroreductase family K19285 - 1.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000251 261.0
PYH3_k127_5263488_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14387 - - 0.0000000000000000000000000000000000000000000000000113 197.0
PYH3_k127_5263488_8 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000009424 191.0
PYH3_k127_5285764_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1146.0
PYH3_k127_5285764_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 409.0
PYH3_k127_5285764_10 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 258.0
PYH3_k127_5285764_11 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009215 237.0
PYH3_k127_5285764_12 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000512 235.0
PYH3_k127_5285764_13 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000002263 176.0
PYH3_k127_5285764_14 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000007102 169.0
PYH3_k127_5285764_15 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000001862 151.0
PYH3_k127_5285764_16 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000002956 149.0
PYH3_k127_5285764_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000001846 110.0
PYH3_k127_5285764_18 FR47-like protein - - - 0.0000000000000000001597 95.0
PYH3_k127_5285764_19 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000001179 81.0
PYH3_k127_5285764_2 enoyl-(acyl-carrier-protein) reductase II K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 379.0
PYH3_k127_5285764_20 DSBA-like thioredoxin domain - - - 0.000003689 56.0
PYH3_k127_5285764_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 354.0
PYH3_k127_5285764_4 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 338.0
PYH3_k127_5285764_5 PFAM short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 289.0
PYH3_k127_5285764_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002047 281.0
PYH3_k127_5285764_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001696 267.0
PYH3_k127_5285764_8 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001246 265.0
PYH3_k127_5285764_9 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002571 269.0
PYH3_k127_5350571_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 469.0
PYH3_k127_5350571_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 301.0
PYH3_k127_5350571_2 Glycoprotease family - - - 0.000000000000000000000000000000000000000000000007032 181.0
PYH3_k127_5350571_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000006226 168.0
PYH3_k127_5350571_4 PFAM thioesterase superfamily - - - 0.0000000000000000000002212 100.0
PYH3_k127_5350571_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000002464 77.0
PYH3_k127_5350571_6 NifU-like domain - - - 0.000000000001779 67.0
PYH3_k127_5350571_7 NifU-like domain - - - 0.00001323 47.0
PYH3_k127_536196_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.228e-220 694.0
PYH3_k127_536196_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 517.0
PYH3_k127_536196_10 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000004672 206.0
PYH3_k127_536196_11 TIGRFAM primosome, DnaD subunit - - - 0.0000000000000000000000000000000000000008835 158.0
PYH3_k127_536196_12 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000001808 143.0
PYH3_k127_536196_13 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000003736 102.0
PYH3_k127_536196_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000001235 87.0
PYH3_k127_536196_15 Cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.0000000000001105 78.0
PYH3_k127_536196_16 HlyD family secretion protein K02005 - - 0.00003308 57.0
PYH3_k127_536196_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000595 50.0
PYH3_k127_536196_18 HNH endonuclease - - - 0.0007114 47.0
PYH3_k127_536196_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 510.0
PYH3_k127_536196_3 Bacterial dnaA protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 478.0
PYH3_k127_536196_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 407.0
PYH3_k127_536196_5 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 412.0
PYH3_k127_536196_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 366.0
PYH3_k127_536196_7 Efflux ABC transporter permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 330.0
PYH3_k127_536196_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 307.0
PYH3_k127_536196_9 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001067 269.0
PYH3_k127_5398638_0 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 491.0
PYH3_k127_5398638_1 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000003798 187.0
PYH3_k127_5398638_2 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000002526 75.0
PYH3_k127_5440329_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 378.0
PYH3_k127_5440329_1 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000000000000000000007835 249.0
PYH3_k127_5440329_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000009327 202.0
PYH3_k127_5440329_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000008737 156.0
PYH3_k127_5440329_4 Acetyltransferase - - - 0.00000000000000000000000000000000000001817 149.0
PYH3_k127_5440329_5 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000003011 147.0
PYH3_k127_5440329_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000002951 136.0
PYH3_k127_5440329_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000008962 70.0
PYH3_k127_5485148_0 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000005729 225.0
PYH3_k127_5485148_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000005688 183.0
PYH3_k127_5485148_2 Acyltransferase family K11941 - - 0.00000000000000000000000000000000005785 149.0
PYH3_k127_5485148_3 - - - - 0.0001561 44.0
PYH3_k127_5505177_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 569.0
PYH3_k127_5505177_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 488.0
PYH3_k127_5505177_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007526 231.0
PYH3_k127_5505177_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000009625 153.0
PYH3_k127_5505177_4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.0006574 46.0
PYH3_k127_5521505_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 446.0
PYH3_k127_5521505_1 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 353.0
PYH3_k127_5521505_2 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001988 267.0
PYH3_k127_5521505_3 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000001106 201.0
PYH3_k127_5521505_4 GYD domain - - - 0.000000000000000008087 87.0
PYH3_k127_5521505_5 - - - - 0.000000000000001054 81.0
PYH3_k127_5521505_6 - - - - 0.0000002329 56.0
PYH3_k127_5616582_0 Tail sheath protein K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 598.0
PYH3_k127_5616582_1 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 430.0
PYH3_k127_5616582_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000003126 217.0
PYH3_k127_5616582_3 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000009647 166.0
PYH3_k127_5616582_4 - - - - 0.000000000000000000000000000000000000000002596 158.0
PYH3_k127_5616582_5 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000004332 145.0
PYH3_k127_5616582_6 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000001631 134.0
PYH3_k127_5616582_7 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000004316 121.0
PYH3_k127_5616582_8 - - - - 0.000000000008022 70.0
PYH3_k127_5616582_9 PAAR repeat-containing protein - - - 0.00000001488 56.0
PYH3_k127_5617029_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 569.0
PYH3_k127_5617029_1 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 523.0
PYH3_k127_5617029_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 406.0
PYH3_k127_5617029_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 407.0
PYH3_k127_5617029_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 396.0
PYH3_k127_5617029_5 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 383.0
PYH3_k127_5617029_6 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 353.0
PYH3_k127_5617029_7 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 325.0
PYH3_k127_5617029_8 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000001978 205.0
PYH3_k127_5629104_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002609 214.0
PYH3_k127_5629104_1 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000003914 190.0
PYH3_k127_5629104_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000001082 149.0
PYH3_k127_5629104_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000009643 120.0
PYH3_k127_5629104_4 - - - - 0.0000000000000000000000000002375 125.0
PYH3_k127_5629104_5 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000007243 93.0
PYH3_k127_5629104_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000606 50.0
PYH3_k127_5638669_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.314e-217 689.0
PYH3_k127_5638669_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 602.0
PYH3_k127_5638669_10 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000001917 220.0
PYH3_k127_5638669_11 competence protein - - - 0.000000000000000000000000000000000000000000000000000000000004942 215.0
PYH3_k127_5638669_12 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000002106 190.0
PYH3_k127_5638669_13 Bifunctional coenzyme A synthase K02318 GO:0000003,GO:0001667,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0003006,GO:0003674,GO:0003824,GO:0004140,GO:0004595,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005759,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006928,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007300,GO:0007303,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0010631,GO:0015936,GO:0015937,GO:0016020,GO:0016301,GO:0016310,GO:0016477,GO:0016482,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019867,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030707,GO:0030855,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040011,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046390,GO:0046483,GO:0046907,GO:0048468,GO:0048477,GO:0048513,GO:0048563,GO:0048569,GO:0048609,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0055086,GO:0055088,GO:0055090,GO:0060429,GO:0060562,GO:0065007,GO:0065008,GO:0070013,GO:0070328,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090130,GO:0090132,GO:0090407,GO:0098588,GO:0098805,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.3 0.0000000000000000000000000000000000000000000004224 173.0
PYH3_k127_5638669_14 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000004212 159.0
PYH3_k127_5638669_15 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000007624 158.0
PYH3_k127_5638669_16 - - - - 0.000000000000000000000000000002536 121.0
PYH3_k127_5638669_17 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000007462 117.0
PYH3_k127_5638669_18 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000007593 119.0
PYH3_k127_5638669_19 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000001161 115.0
PYH3_k127_5638669_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 596.0
PYH3_k127_5638669_20 - - - - 0.0000000006732 61.0
PYH3_k127_5638669_21 - - - - 0.00000001572 58.0
PYH3_k127_5638669_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 314.0
PYH3_k127_5638669_4 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 309.0
PYH3_k127_5638669_5 GTP cyclohydrolase I activity K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 292.0
PYH3_k127_5638669_6 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004941 275.0
PYH3_k127_5638669_7 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009552 251.0
PYH3_k127_5638669_8 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004955 248.0
PYH3_k127_5638669_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000003698 229.0
PYH3_k127_5672288_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 394.0
PYH3_k127_5672288_1 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000501 188.0
PYH3_k127_5672288_2 CoA-transferase family III K07544 - 2.8.3.15 0.00000000000000000000000000000000000000000000003749 179.0
PYH3_k127_5672288_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000001256 75.0
PYH3_k127_5698284_0 Domain of unknown function (DUF1998) K06877 - - 9.101e-198 629.0
PYH3_k127_5698284_1 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 528.0
PYH3_k127_5698284_2 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000012 279.0
PYH3_k127_5698284_3 Protein conserved in bacteria K09764 - - 0.00000000000000000003646 93.0
PYH3_k127_5698284_4 Helix-turn-helix - - - 0.0000000000000000005606 88.0
PYH3_k127_5698284_5 - - - - 0.000000000000001371 77.0
PYH3_k127_5698284_6 - - - - 0.000000000000004511 78.0
PYH3_k127_5894178_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 374.0
PYH3_k127_5894178_1 Peptide ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000264 276.0
PYH3_k127_5894178_2 Sulfatase - - - 0.000000000000000000000172 104.0
PYH3_k127_5927848_0 hydrogenase large subunit K06281 - 1.12.99.6 1.414e-219 689.0
PYH3_k127_5927848_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 387.0
PYH3_k127_5927848_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000003879 221.0
PYH3_k127_5987994_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 6.392e-206 650.0
PYH3_k127_5987994_1 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001198 270.0
PYH3_k127_5987994_2 Alpha/beta hydrolase family K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000007148 241.0
PYH3_k127_5987994_3 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000005585 208.0
PYH3_k127_5987994_4 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000000000000000000000000000000000001393 193.0
PYH3_k127_5987994_5 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.00000000000000000000000000000000000000000001898 167.0
PYH3_k127_5987994_6 Metallo-beta-lactamase superfamily K05555 - - 0.00000000000000000000000005751 117.0
PYH3_k127_5987994_7 PFAM regulatory protein TetR - - - 0.00000000001683 72.0
PYH3_k127_5987994_8 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000003088 60.0
PYH3_k127_5987994_9 sh3 domain protein - - - 0.000005019 51.0
PYH3_k127_5997237_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266,K03388 - 1.4.1.13,1.4.1.14,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 530.0
PYH3_k127_5997237_1 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 338.0
PYH3_k127_5997237_2 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000001261 192.0
PYH3_k127_5997237_3 Flavodoxin - - - 0.000000000000000000000000000009522 123.0
PYH3_k127_5997237_4 - - - - 0.00000000001051 67.0
PYH3_k127_5997237_5 - - - - 0.000000004675 66.0
PYH3_k127_6020828_0 Endopeptidase La - - - 7.767e-220 707.0
PYH3_k127_6020828_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
PYH3_k127_6020828_2 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000001644 55.0
PYH3_k127_6151601_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 8.42e-205 676.0
PYH3_k127_6151601_1 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003854 241.0
PYH3_k127_6160022_0 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 1.586e-236 742.0
PYH3_k127_6160022_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 4.186e-194 612.0
PYH3_k127_6160022_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 316.0
PYH3_k127_6216581_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0 1241.0
PYH3_k127_6216581_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.158e-308 956.0
PYH3_k127_6216581_10 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001164 249.0
PYH3_k127_6216581_11 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000001057 156.0
PYH3_k127_6216581_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000226 141.0
PYH3_k127_6216581_13 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000247 138.0
PYH3_k127_6216581_14 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000001811 87.0
PYH3_k127_6216581_15 PFAM Cyclic nucleotide-binding domain - - - 0.000000000000007939 81.0
PYH3_k127_6216581_16 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000171 44.0
PYH3_k127_6216581_2 HMGL-like K02594 - 2.3.3.14 1.44e-202 639.0
PYH3_k127_6216581_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
PYH3_k127_6216581_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 512.0
PYH3_k127_6216581_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 420.0
PYH3_k127_6216581_6 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 361.0
PYH3_k127_6216581_7 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
PYH3_k127_6216581_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000007654 252.0
PYH3_k127_6216581_9 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001521 253.0
PYH3_k127_6221232_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 9.65e-277 869.0
PYH3_k127_6221232_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.39e-228 721.0
PYH3_k127_6221232_10 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 428.0
PYH3_k127_6221232_11 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 416.0
PYH3_k127_6221232_12 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 374.0
PYH3_k127_6221232_13 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
PYH3_k127_6221232_14 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 319.0
PYH3_k127_6221232_15 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 298.0
PYH3_k127_6221232_16 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 293.0
PYH3_k127_6221232_17 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000009148 264.0
PYH3_k127_6221232_18 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 265.0
PYH3_k127_6221232_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 245.0
PYH3_k127_6221232_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.895e-203 636.0
PYH3_k127_6221232_20 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000005991 210.0
PYH3_k127_6221232_21 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000007191 168.0
PYH3_k127_6221232_22 PFAM heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000006042 167.0
PYH3_k127_6221232_23 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000006044 165.0
PYH3_k127_6221232_24 - - - - 0.000000000000000000000000000000000000000008148 161.0
PYH3_k127_6221232_25 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000005865 110.0
PYH3_k127_6221232_26 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000002181 109.0
PYH3_k127_6221232_27 Bacterial protein of unknown function (DUF951) - - - 0.00000000000000000000001104 101.0
PYH3_k127_6221232_28 Protein of unknown function (DUF448) K07742 - - 0.0000000000000000001928 91.0
PYH3_k127_6221232_29 - - - - 0.000000000000000002881 94.0
PYH3_k127_6221232_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 546.0
PYH3_k127_6221232_30 Transcription factor zinc-finger K09981 - - 0.000000000007236 75.0
PYH3_k127_6221232_31 - - - - 0.0000000002549 70.0
PYH3_k127_6221232_32 - - - - 0.00000002522 59.0
PYH3_k127_6221232_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 516.0
PYH3_k127_6221232_5 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 508.0
PYH3_k127_6221232_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 487.0
PYH3_k127_6221232_7 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 481.0
PYH3_k127_6221232_8 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 464.0
PYH3_k127_6221232_9 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 434.0
PYH3_k127_6289241_0 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 492.0
PYH3_k127_6289241_1 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 410.0
PYH3_k127_6289241_2 Telomere recombination K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 342.0
PYH3_k127_6289241_3 sAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000001618 194.0
PYH3_k127_6289241_4 NUDIX domain - - - 0.000000000000000000000000000001225 128.0
PYH3_k127_6289241_5 HupF/HypC family K04653 - - 0.000000000000000004345 85.0
PYH3_k127_6317449_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 305.0
PYH3_k127_6317449_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 292.0
PYH3_k127_6317449_2 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000001142 253.0
PYH3_k127_6317449_3 Electron transfer flavoprotein domain K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000001274 153.0
PYH3_k127_6317449_4 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000004578 145.0
PYH3_k127_6317449_5 Protein of unknown function (DUF664) - - - 0.00000000000112 73.0
PYH3_k127_6335615_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 5.83e-306 948.0
PYH3_k127_6335615_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 613.0
PYH3_k127_6335615_10 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000000007661 151.0
PYH3_k127_6335615_11 Ecdysteroid kinase - - - 0.0000000000000000000000000006517 120.0
PYH3_k127_6335615_2 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 520.0
PYH3_k127_6335615_3 malic enzyme K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 448.0
PYH3_k127_6335615_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 372.0
PYH3_k127_6335615_5 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 372.0
PYH3_k127_6335615_6 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 341.0
PYH3_k127_6335615_7 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
PYH3_k127_6335615_8 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000004265 193.0
PYH3_k127_6335615_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004462 169.0
PYH3_k127_6393230_0 Elongator protein 3, MiaB family, Radical SAM - - - 5.172e-232 733.0
PYH3_k127_6393230_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 345.0
PYH3_k127_6393230_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 292.0
PYH3_k127_6393230_3 - - - - 0.000000000000000000000000803 108.0
PYH3_k127_6393230_4 OsmC-like protein K07397 - - 0.000000000000000000003776 101.0
PYH3_k127_6393230_5 Zinc ribbon domain - - - 0.0000000000013 70.0
PYH3_k127_6432807_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1729.0
PYH3_k127_6432807_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1416.0
PYH3_k127_6432807_10 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 328.0
PYH3_k127_6432807_11 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 326.0
PYH3_k127_6432807_12 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 314.0
PYH3_k127_6432807_13 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 302.0
PYH3_k127_6432807_14 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 283.0
PYH3_k127_6432807_15 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001046 258.0
PYH3_k127_6432807_16 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001577 254.0
PYH3_k127_6432807_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000006993 248.0
PYH3_k127_6432807_18 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000002046 247.0
PYH3_k127_6432807_19 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001709 254.0
PYH3_k127_6432807_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.166e-277 868.0
PYH3_k127_6432807_20 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000001584 235.0
PYH3_k127_6432807_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000001344 232.0
PYH3_k127_6432807_22 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000001482 219.0
PYH3_k127_6432807_23 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
PYH3_k127_6432807_24 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000001508 215.0
PYH3_k127_6432807_25 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000138 198.0
PYH3_k127_6432807_26 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000636 195.0
PYH3_k127_6432807_27 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000001202 196.0
PYH3_k127_6432807_28 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000007936 189.0
PYH3_k127_6432807_29 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000003643 179.0
PYH3_k127_6432807_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 8.607e-204 651.0
PYH3_k127_6432807_30 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000005207 175.0
PYH3_k127_6432807_31 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000003612 170.0
PYH3_k127_6432807_32 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000004908 170.0
PYH3_k127_6432807_33 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000003026 165.0
PYH3_k127_6432807_34 Dihydroxyacetone kinase family - - - 0.00000000000000000000000000000000000000000007433 171.0
PYH3_k127_6432807_35 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000002994 161.0
PYH3_k127_6432807_36 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000002744 160.0
PYH3_k127_6432807_37 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000428 166.0
PYH3_k127_6432807_38 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000007113 155.0
PYH3_k127_6432807_39 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000007817 158.0
PYH3_k127_6432807_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 559.0
PYH3_k127_6432807_40 structural constituent of ribosome K02879 - - 0.00000000000000000000000000000000000000002705 154.0
PYH3_k127_6432807_41 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001504 147.0
PYH3_k127_6432807_42 Chromatin associated protein KTI12 - - - 0.000000000000000000000000000000000006005 144.0
PYH3_k127_6432807_43 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000001626 137.0
PYH3_k127_6432807_44 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000009395 134.0
PYH3_k127_6432807_45 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000002183 127.0
PYH3_k127_6432807_46 Ribosomal protein S16 K02959 - - 0.000000000000000000000000000003628 121.0
PYH3_k127_6432807_47 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000004259 113.0
PYH3_k127_6432807_48 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000001893 111.0
PYH3_k127_6432807_49 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001181 107.0
PYH3_k127_6432807_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 541.0
PYH3_k127_6432807_50 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000003057 103.0
PYH3_k127_6432807_51 KH domain K06960 - - 0.0000000000000000000000551 102.0
PYH3_k127_6432807_52 - - - - 0.000000000000000000002686 100.0
PYH3_k127_6432807_53 Phosphoesterase K07095 - - 0.00000000000000000004191 96.0
PYH3_k127_6432807_54 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000004013 89.0
PYH3_k127_6432807_55 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002443 87.0
PYH3_k127_6432807_56 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009374 68.0
PYH3_k127_6432807_57 structural constituent of ribosome K02904 - - 0.00000000008804 64.0
PYH3_k127_6432807_58 - - - - 0.00000002409 61.0
PYH3_k127_6432807_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 490.0
PYH3_k127_6432807_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 420.0
PYH3_k127_6432807_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 365.0
PYH3_k127_6432807_9 IMP dehydrogenase / GMP reductase domain K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
PYH3_k127_6441714_0 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 358.0
PYH3_k127_6441714_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000104 289.0
PYH3_k127_6441714_2 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000008115 139.0
PYH3_k127_6441714_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000005219 91.0
PYH3_k127_6441714_4 xylan catabolic process K03932 - - 0.000000000000000002313 96.0
PYH3_k127_6441714_5 Short C-terminal domain K08982 - - 0.0000000000004962 72.0
PYH3_k127_6441714_6 dehydratase - - - 0.000001146 56.0
PYH3_k127_6441714_8 MaoC like domain - - - 0.00002199 52.0
PYH3_k127_6488687_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 349.0
PYH3_k127_6488687_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000007404 218.0
PYH3_k127_6488687_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000004099 214.0
PYH3_k127_6488687_3 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000008312 207.0
PYH3_k127_6488687_4 acyl-CoA dehydrogenase - - - 0.00000000000000000000002582 105.0
PYH3_k127_6501872_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 558.0
PYH3_k127_6501872_1 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 309.0
PYH3_k127_6501872_2 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 308.0
PYH3_k127_6501872_3 Thioredoxin - - - 0.0000000000000000000000000003889 121.0
PYH3_k127_6501872_4 KR domain - - - 0.000000000000000000000003132 104.0
PYH3_k127_6501872_5 Glutaredoxin - - - 0.00008505 48.0
PYH3_k127_6568891_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 466.0
PYH3_k127_6568891_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 321.0
PYH3_k127_6568891_2 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 293.0
PYH3_k127_6568891_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001038 282.0
PYH3_k127_6568891_4 Cupin domain - - - 0.000000000000000000000000000004316 123.0
PYH3_k127_6568891_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000001548 121.0
PYH3_k127_6568891_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000001114 108.0
PYH3_k127_6568891_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000005264 89.0
PYH3_k127_6705210_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 2.005e-287 896.0
PYH3_k127_6705210_1 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 428.0
PYH3_k127_6705210_2 Dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 318.0
PYH3_k127_6705210_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000003942 179.0
PYH3_k127_6705210_4 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000007883 152.0
PYH3_k127_6705210_5 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000001294 136.0
PYH3_k127_6705210_6 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 0.0000000000000000000000000000001564 127.0
PYH3_k127_6713840_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.344e-218 704.0
PYH3_k127_6713840_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 484.0
PYH3_k127_6713840_10 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000006266 159.0
PYH3_k127_6713840_11 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000006047 146.0
PYH3_k127_6713840_12 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000005485 115.0
PYH3_k127_6713840_2 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 386.0
PYH3_k127_6713840_3 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 346.0
PYH3_k127_6713840_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 310.0
PYH3_k127_6713840_5 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 306.0
PYH3_k127_6713840_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001521 282.0
PYH3_k127_6713840_7 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007261 280.0
PYH3_k127_6713840_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000004381 251.0
PYH3_k127_6713840_9 3-hydroxyacyl-CoA dehydrogenase K00074,K15016,K15019 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0043956 1.1.1.157,1.1.1.35,4.2.1.116,4.2.1.17 0.000000000000000000000000000000000000000001046 166.0
PYH3_k127_6829245_0 AMP-binding enzyme C-terminal domain - - - 1.245e-216 683.0
PYH3_k127_6829245_1 PFAM sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 461.0
PYH3_k127_6829245_2 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 441.0
PYH3_k127_6829245_3 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002111 238.0
PYH3_k127_6829245_4 Flavin reductase-like protein - - - 0.000000000000000000000000000000000000000132 157.0
PYH3_k127_6829245_5 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000005849 160.0
PYH3_k127_6829245_6 GYD domain - - - 0.000000000000000000000000000002201 124.0
PYH3_k127_6829245_7 - - - - 0.0000000005994 70.0
PYH3_k127_6874173_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 544.0
PYH3_k127_6874173_1 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 539.0
PYH3_k127_6874173_10 Carboxymuconolactone decarboxylase family - - - 0.0000000000000003647 83.0
PYH3_k127_6874173_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 381.0
PYH3_k127_6874173_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 365.0
PYH3_k127_6874173_4 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 327.0
PYH3_k127_6874173_5 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003987 287.0
PYH3_k127_6874173_6 acetyl coenzyme A synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004017 287.0
PYH3_k127_6874173_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
PYH3_k127_6874173_8 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000001525 171.0
PYH3_k127_6874173_9 FAD-dependent K07137 - - 0.000000000000000000000206 97.0
PYH3_k127_6887016_0 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
PYH3_k127_6887016_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000004422 213.0
PYH3_k127_6887016_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000003746 194.0
PYH3_k127_6887016_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000004899 190.0
PYH3_k127_6887016_4 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000002719 170.0
PYH3_k127_6887016_5 Conserved hypothetical protein (Lin0512_fam) - - - 0.00000000000000000000003422 102.0
PYH3_k127_6887016_6 Alcohol dehydrogenase GroES domain protein K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000003934 100.0
PYH3_k127_6887016_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000006646 60.0
PYH3_k127_6957974_0 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 455.0
PYH3_k127_6966483_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 4.971e-204 643.0
PYH3_k127_6966483_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000038 225.0
PYH3_k127_6966483_2 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.00000000000000000000000186 106.0
PYH3_k127_6966483_3 - - - - 0.000000000000000000000004521 109.0
PYH3_k127_6966483_4 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000001632 70.0
PYH3_k127_6983857_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.614e-260 834.0
PYH3_k127_6983857_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.775e-234 741.0
PYH3_k127_6983857_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 491.0
PYH3_k127_6983857_3 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 296.0
PYH3_k127_6983857_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000008022 203.0
PYH3_k127_6983857_5 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000007663 165.0
PYH3_k127_701190_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 344.0
PYH3_k127_701190_1 Immune inhibitor A peptidase M6 K09607 - - 0.0000000000000000000000000000000000000000000000000000005053 197.0
PYH3_k127_7036822_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 2.269e-282 879.0
PYH3_k127_7036822_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.413e-194 618.0
PYH3_k127_7036822_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000001099 168.0
PYH3_k127_7036822_11 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000004969 136.0
PYH3_k127_7036822_12 - - - - 0.0000000000000000000000000000003688 124.0
PYH3_k127_7036822_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000001114 124.0
PYH3_k127_7036822_14 methyltransferase - - - 0.0000000000000000000006154 98.0
PYH3_k127_7036822_15 - - - - 0.000000000000000000117 88.0
PYH3_k127_7036822_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 539.0
PYH3_k127_7036822_3 CO dehydrogenase/acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 444.0
PYH3_k127_7036822_4 Pterin binding enzyme K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 334.0
PYH3_k127_7036822_5 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 315.0
PYH3_k127_7036822_6 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003217 277.0
PYH3_k127_7036822_7 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000003869 223.0
PYH3_k127_7036822_8 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000007237 197.0
PYH3_k127_7036822_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000001847 181.0
PYH3_k127_7179381_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000005993 240.0
PYH3_k127_7179381_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000005363 215.0
PYH3_k127_7179381_2 Efflux ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000001045 221.0
PYH3_k127_7179381_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000001489 125.0
PYH3_k127_7179381_4 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000001063 89.0
PYH3_k127_7179381_5 Domain of unknown function (DUF4418) - - - 0.00000000000001546 79.0
PYH3_k127_7179381_6 Protein of unknown function (DUF998) - - - 0.00004073 54.0
PYH3_k127_7179381_7 Cupredoxin-like domain - - - 0.00007439 46.0
PYH3_k127_7305497_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.826e-195 616.0
PYH3_k127_7305497_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001982 254.0
PYH3_k127_7305497_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000032 244.0
PYH3_k127_7305497_3 MgtC family K07507 - - 0.00000000000000000000000000000000002562 138.0
PYH3_k127_7305497_4 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000000003564 94.0
PYH3_k127_7305497_5 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000000000001528 90.0
PYH3_k127_7305497_6 GIY-YIG catalytic domain K07461 - - 0.000000000000003748 76.0
PYH3_k127_7305497_7 GIY-YIG catalytic domain K07461 - - 0.00000000003867 63.0
PYH3_k127_7370064_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 290.0
PYH3_k127_7370064_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007336 284.0
PYH3_k127_7370064_2 This gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003903 280.0
PYH3_k127_7370064_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001722 273.0
PYH3_k127_7370064_4 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate - - - 0.000000000000000000000000000000000000000000000001729 188.0
PYH3_k127_7370064_5 Chloramphenicol phosphotransferase-like protein K18554 - - 0.00000000000000000000000000000000000000000002228 168.0
PYH3_k127_737254_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 512.0
PYH3_k127_737254_1 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 473.0
PYH3_k127_737254_10 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 264.0
PYH3_k127_737254_11 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005749 248.0
PYH3_k127_737254_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH3_k127_737254_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000575 217.0
PYH3_k127_737254_14 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000000000000000000000000000004057 210.0
PYH3_k127_737254_15 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000008276 210.0
PYH3_k127_737254_16 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000007082 177.0
PYH3_k127_737254_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000755 170.0
PYH3_k127_737254_18 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000002862 151.0
PYH3_k127_737254_19 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000001005 148.0
PYH3_k127_737254_2 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 429.0
PYH3_k127_737254_20 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000005574 146.0
PYH3_k127_737254_21 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000266 124.0
PYH3_k127_737254_22 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000001652 56.0
PYH3_k127_737254_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 422.0
PYH3_k127_737254_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
PYH3_k127_737254_5 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 383.0
PYH3_k127_737254_6 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 361.0
PYH3_k127_737254_7 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 351.0
PYH3_k127_737254_8 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH3_k127_737254_9 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 267.0
PYH3_k127_7385811_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.384e-233 737.0
PYH3_k127_7385811_1 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 424.0
PYH3_k127_7385811_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000006438 154.0
PYH3_k127_7385811_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 409.0
PYH3_k127_7385811_3 leucine import across plasma membrane K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 310.0
PYH3_k127_7385811_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 309.0
PYH3_k127_7385811_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004918 275.0
PYH3_k127_7385811_6 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009284 274.0
PYH3_k127_7385811_7 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000874 265.0
PYH3_k127_7385811_8 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000008491 224.0
PYH3_k127_7385811_9 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000002062 180.0
PYH3_k127_7386068_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.102e-241 754.0
PYH3_k127_7386068_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.949e-237 740.0
PYH3_k127_7386068_10 ABC transporter K02003 - - 0.000000000000000000000000000000000000000003603 160.0
PYH3_k127_7386068_11 Zincin-like metallopeptidase - - - 0.00000000000000000000000000001565 121.0
PYH3_k127_7386068_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000007069 119.0
PYH3_k127_7386068_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000002508 98.0
PYH3_k127_7386068_14 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000000001454 79.0
PYH3_k127_7386068_16 - - - - 0.000000002929 63.0
PYH3_k127_7386068_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000005062 56.0
PYH3_k127_7386068_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 385.0
PYH3_k127_7386068_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 312.0
PYH3_k127_7386068_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005283 257.0
PYH3_k127_7386068_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
PYH3_k127_7386068_6 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
PYH3_k127_7386068_7 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000001967 239.0
PYH3_k127_7386068_8 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000003041 189.0
PYH3_k127_7386068_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000002358 164.0
PYH3_k127_7396403_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5.132e-249 786.0
PYH3_k127_7396403_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 7.927e-218 687.0
PYH3_k127_7396403_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 428.0
PYH3_k127_7396403_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000005845 205.0
PYH3_k127_7396403_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000412 181.0
PYH3_k127_7396403_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000002386 157.0
PYH3_k127_7396403_6 Phospholipid methyltransferase - - - 0.0000000000000000000000004553 111.0
PYH3_k127_7396403_7 Aminotransferase - - - 0.0008668 42.0
PYH3_k127_7415767_0 Radical_SAM C-terminal domain K07739 - 2.3.1.48 1.631e-202 639.0
PYH3_k127_7415767_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 314.0
PYH3_k127_7415767_10 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000000004412 79.0
PYH3_k127_7415767_11 - - - - 0.0000000000001234 73.0
PYH3_k127_7415767_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 310.0
PYH3_k127_7415767_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001293 223.0
PYH3_k127_7415767_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000002633 194.0
PYH3_k127_7415767_5 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000008344 168.0
PYH3_k127_7415767_6 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000000000000004632 140.0
PYH3_k127_7415767_7 D-galactarate dehydratase altronate hydrolase - - - 0.00000000000000000000000000000000001573 138.0
PYH3_k127_7415767_8 GH3 auxin-responsive promoter - - - 0.000000000000000000000003152 116.0
PYH3_k127_7415767_9 - - - - 0.00000000000000000002181 95.0
PYH3_k127_74523_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 539.0
PYH3_k127_74523_1 E3 Ubiquitin ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 426.0
PYH3_k127_74523_10 - - - - 0.00000000003128 64.0
PYH3_k127_74523_2 PFAM Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 297.0
PYH3_k127_74523_3 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001259 282.0
PYH3_k127_74523_4 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000761 233.0
PYH3_k127_74523_5 - - - - 0.000000000000000000000000000000000000000000000000000000000004863 217.0
PYH3_k127_74523_6 PAC2 family - - - 0.0000000000000000000000000000000000000000000009267 175.0
PYH3_k127_74523_7 - - - - 0.000000000000000000000000000007768 128.0
PYH3_k127_74523_8 HicB family - - - 0.0000000000000001524 84.0
PYH3_k127_7458997_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 568.0
PYH3_k127_7458997_1 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 413.0
PYH3_k127_7458997_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 372.0
PYH3_k127_7458997_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 299.0
PYH3_k127_7458997_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008509 270.0
PYH3_k127_7458997_5 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000002162 181.0
PYH3_k127_7458997_6 RDD family - - - 0.0000000000000000000001455 104.0
PYH3_k127_7458997_7 PspC domain - - - 0.00000000000000000002054 96.0
PYH3_k127_7458997_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000117 93.0
PYH3_k127_7458997_9 membrane - - - 0.000000001666 68.0
PYH3_k127_7542703_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 3.429e-222 711.0
PYH3_k127_7542703_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 595.0
PYH3_k127_7542703_2 Binding-protein-dependent transport system inner membrane component K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 350.0
PYH3_k127_7542703_3 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000007254 230.0
PYH3_k127_7629987_0 Conserved region in glutamate synthase - - - 8.712e-262 812.0
PYH3_k127_7629987_1 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 562.0
PYH3_k127_7629987_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 522.0
PYH3_k127_7629987_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 416.0
PYH3_k127_7629987_4 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 318.0
PYH3_k127_7629987_5 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000128 153.0
PYH3_k127_765546_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 297.0
PYH3_k127_765546_1 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000006971 156.0
PYH3_k127_765546_2 AP endonuclease family 2 K01151 - 3.1.21.2 0.000000000000000000000000000007288 122.0
PYH3_k127_7670481_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5e-324 1002.0
PYH3_k127_7670481_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.667e-242 762.0
PYH3_k127_7670481_11 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000001561 65.0
PYH3_k127_7670481_2 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 499.0
PYH3_k127_7670481_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 456.0
PYH3_k127_7670481_4 Two component transcriptional regulator, winged helix family K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003231 282.0
PYH3_k127_7670481_5 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004713 256.0
PYH3_k127_7670481_6 histidine kinase, HAMP K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001294 241.0
PYH3_k127_7670481_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000003408 235.0
PYH3_k127_7670481_8 lipoprotein transporter activity K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000002913 224.0
PYH3_k127_7670481_9 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000000001277 175.0
PYH3_k127_7715462_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 580.0
PYH3_k127_7715462_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 302.0
PYH3_k127_7715462_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000002196 71.0
PYH3_k127_7715462_3 - - - - 0.0000000000004666 72.0
PYH3_k127_7715462_4 Signal peptide protein - - - 0.0000000001445 65.0
PYH3_k127_7715462_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000004932 51.0
PYH3_k127_7724116_0 - - - - 0.0000000000000000000000000000000000000000000000000000003625 208.0
PYH3_k127_7724116_1 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000229 164.0
PYH3_k127_7724116_2 amidohydrolase K07045 - - 0.000000000000000000000005111 110.0
PYH3_k127_7859781_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 4.808e-291 906.0
PYH3_k127_7859781_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 2.559e-285 885.0
PYH3_k127_7859781_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 411.0
PYH3_k127_7859781_3 - - - - 0.00000007591 57.0
PYH3_k127_7865215_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 395.0
PYH3_k127_7865215_1 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001096 275.0
PYH3_k127_7865215_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000166 265.0
PYH3_k127_7872683_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 494.0
PYH3_k127_7872683_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 349.0
PYH3_k127_7931203_0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 K03738 - 1.2.7.5 3.189e-226 716.0
PYH3_k127_7931203_1 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 389.0
PYH3_k127_7931203_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055,K01259,K09023,K14727,K16434 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.1.1.24,3.4.11.5,4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000003348 236.0
PYH3_k127_7931203_3 Serine aminopeptidase, S33 K01048 GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 0.00000000000000000000000000000001306 132.0
PYH3_k127_7934104_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.07e-219 699.0
PYH3_k127_7934104_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 507.0
PYH3_k127_7934104_10 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000003076 148.0
PYH3_k127_7934104_11 4Fe-4S dicluster domain K05580 - 1.6.5.3 0.00000000000000000000000000000000004188 139.0
PYH3_k127_7934104_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.00000000000000000000000000000001001 130.0
PYH3_k127_7934104_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000004913 124.0
PYH3_k127_7934104_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 490.0
PYH3_k127_7934104_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 477.0
PYH3_k127_7934104_4 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 395.0
PYH3_k127_7934104_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 391.0
PYH3_k127_7934104_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 363.0
PYH3_k127_7934104_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001609 268.0
PYH3_k127_7934104_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000009092 252.0
PYH3_k127_7934104_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003168 237.0
PYH3_k127_797998_0 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002858 278.0
PYH3_k127_797998_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000006887 237.0
PYH3_k127_797998_2 Belongs to the peptidase M50B family - - - 0.000000000000000000466 96.0
PYH3_k127_797998_3 acetyl-coa acetyltransferase - - - 0.00003161 49.0
PYH3_k127_797998_4 - - - - 0.0001452 49.0
PYH3_k127_797998_5 Putative auto-transporter adhesin, head GIN domain - - - 0.0003761 47.0
PYH3_k127_7994230_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 359.0
PYH3_k127_7994230_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 324.0
PYH3_k127_7994230_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 314.0
PYH3_k127_7994230_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003344 286.0
PYH3_k127_7994230_4 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002234 277.0
PYH3_k127_7994230_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001809 120.0
PYH3_k127_7994230_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000005751 127.0
PYH3_k127_7994230_8 - - - - 0.00001716 49.0
PYH3_k127_8013713_0 Alpha-2-Macroglobulin K03910,K06530 GO:0000768,GO:0001932,GO:0001933,GO:0001942,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002576,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006949,GO:0006950,GO:0006952,GO:0007275,GO:0008150,GO:0008285,GO:0008544,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009653,GO:0009888,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0010837,GO:0010839,GO:0012505,GO:0012506,GO:0016020,GO:0016192,GO:0017015,GO:0019220,GO:0019222,GO:0019838,GO:0019955,GO:0022404,GO:0022405,GO:0023051,GO:0023057,GO:0030097,GO:0030099,GO:0030141,GO:0030154,GO:0030316,GO:0030512,GO:0030659,GO:0030667,GO:0030856,GO:0031090,GO:0031091,GO:0031092,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031410,GO:0031982,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032940,GO:0042127,GO:0042303,GO:0042325,GO:0042326,GO:0042633,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043588,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045595,GO:0045604,GO:0045616,GO:0045682,GO:0045936,GO:0046903,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048583,GO:0048585,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050431,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050829,GO:0050830,GO:0050896,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051704,GO:0051707,GO:0060255,GO:0060429,GO:0061041,GO:0061045,GO:0065007,GO:0071944,GO:0072674,GO:0072675,GO:0080090,GO:0080134,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0097708,GO:0098542,GO:0098588,GO:0098773,GO:0098805,GO:0099503,GO:1903034,GO:1903035,GO:1903844,GO:1903845,GO:2000026 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 466.0
PYH3_k127_8013713_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003544 274.0
PYH3_k127_8028051_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.627e-259 816.0
PYH3_k127_8028051_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.538e-236 745.0
PYH3_k127_8028051_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 307.0
PYH3_k127_8028051_11 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 301.0
PYH3_k127_8028051_12 Formyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006346 277.0
PYH3_k127_8028051_13 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000000000007082 217.0
PYH3_k127_8028051_14 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000001029 201.0
PYH3_k127_8028051_15 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000002129 148.0
PYH3_k127_8028051_16 FMN-dependent dehydrogenase K00459 - 1.13.12.16 0.00000000000000000000000000000000001905 147.0
PYH3_k127_8028051_17 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000003184 108.0
PYH3_k127_8028051_18 Acetyltransferase (GNAT) domain K03817 - - 0.0000000000000000000002882 101.0
PYH3_k127_8028051_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 531.0
PYH3_k127_8028051_20 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000001072 96.0
PYH3_k127_8028051_21 Protein of unknown function (DUF664) - - - 0.000000000000000002798 91.0
PYH3_k127_8028051_22 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000004897 83.0
PYH3_k127_8028051_23 His Kinase A (phosphoacceptor) domain - - - 0.000000000000001969 86.0
PYH3_k127_8028051_24 nitrite transmembrane transporter activity K02575,K08223 - - 0.00000000000003522 85.0
PYH3_k127_8028051_25 Major Facilitator Superfamily - - - 0.000000000000241 82.0
PYH3_k127_8028051_26 - - - - 0.00003186 46.0
PYH3_k127_8028051_27 Phospholipase_D-nuclease N-terminal - - - 0.0006972 44.0
PYH3_k127_8028051_3 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 480.0
PYH3_k127_8028051_4 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 418.0
PYH3_k127_8028051_5 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 356.0
PYH3_k127_8028051_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 332.0
PYH3_k127_8028051_7 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 338.0
PYH3_k127_8028051_8 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 321.0
PYH3_k127_8028051_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 326.0
PYH3_k127_8029783_0 DNA-directed DNA polymerase K00960,K02337,K14162 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 0.0 1545.0
PYH3_k127_8029783_1 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 522.0
PYH3_k127_8029783_10 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000001986 124.0
PYH3_k127_8029783_11 - - - - 0.00000005178 57.0
PYH3_k127_8029783_13 PFAM ApbE family K09740 - - 0.00007437 47.0
PYH3_k127_8029783_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 493.0
PYH3_k127_8029783_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 449.0
PYH3_k127_8029783_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 400.0
PYH3_k127_8029783_5 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 377.0
PYH3_k127_8029783_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 285.0
PYH3_k127_8029783_7 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000001856 232.0
PYH3_k127_8029783_8 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000007613 235.0
PYH3_k127_8029783_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000007279 155.0
PYH3_k127_8036033_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 1.995e-202 634.0
PYH3_k127_8036033_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 496.0
PYH3_k127_8036033_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003375 264.0
PYH3_k127_8036033_3 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000005158 213.0
PYH3_k127_8044397_0 Phage portal protein, SPP1 Gp6-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 567.0
PYH3_k127_8044397_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 556.0
PYH3_k127_8044397_10 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000001687 67.0
PYH3_k127_8044397_2 Phage capsid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 488.0
PYH3_k127_8044397_3 PFAM FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 362.0
PYH3_k127_8044397_4 - - - - 0.000000000000000000000000000000000000000000000002421 180.0
PYH3_k127_8044397_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000008821 157.0
PYH3_k127_8044397_6 - - - - 0.00000000000000000000000000000000009574 134.0
PYH3_k127_8044397_8 - - - - 0.0000000000000001436 82.0
PYH3_k127_8044397_9 - - - - 0.0000000000006311 71.0
PYH3_k127_8086420_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 7.327e-220 688.0
PYH3_k127_8086420_2 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000004057 148.0
PYH3_k127_8086420_3 TIGRFAM Ammonium transporter K03320 - - 0.00000000001922 65.0
PYH3_k127_8086420_4 Amidohydrolase K07045 - - 0.0006033 49.0
PYH3_k127_8135633_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 555.0
PYH3_k127_8135633_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 334.0
PYH3_k127_8135633_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 313.0
PYH3_k127_8135633_3 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 317.0
PYH3_k127_8135633_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000008193 139.0
PYH3_k127_8135633_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K00663 - 2.3.1.57,2.3.1.82 0.0000000000000000000000001591 110.0
PYH3_k127_8135633_6 Domain of unknown function (DUF1893) - - - 0.0000000000004235 76.0
PYH3_k127_8182323_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 565.0
PYH3_k127_8182323_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 344.0
PYH3_k127_8182323_2 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 258.0
PYH3_k127_8182323_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000004613 229.0
PYH3_k127_8182323_4 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000269 198.0
PYH3_k127_8182323_5 serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000001901 199.0
PYH3_k127_8182323_6 PFAM HD domain - - - 0.000000000000000000000000000000000000000000003722 171.0
PYH3_k127_8182323_7 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000008522 133.0
PYH3_k127_8182323_8 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00001004 51.0
PYH3_k127_8182323_9 FHA domain protein - - - 0.00005146 53.0
PYH3_k127_8228468_0 ABC transporter K06158 - - 5.848e-208 666.0
PYH3_k127_8228468_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004533 238.0
PYH3_k127_8228468_2 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH3_k127_8228468_3 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000006515 175.0
PYH3_k127_8228468_4 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000001638 68.0
PYH3_k127_8300422_0 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 488.0
PYH3_k127_8300422_1 Dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 459.0
PYH3_k127_8300422_2 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 442.0
PYH3_k127_8300422_3 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
PYH3_k127_8300422_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005519 257.0
PYH3_k127_8300422_5 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000002002 226.0
PYH3_k127_8300422_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001887 226.0
PYH3_k127_8300422_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000001388 215.0
PYH3_k127_8357238_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 509.0
PYH3_k127_8357238_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000005259 237.0
PYH3_k127_8357238_2 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000001743 203.0
PYH3_k127_8357238_3 PFAM molybdopterin oxidoreductase Fe4S4 region - - - 0.0000000000000000000000000000000000000000000000000001774 188.0
PYH3_k127_8357238_4 RDD family - - - 0.0000000000000000007768 91.0
PYH3_k127_8369727_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.42e-214 674.0
PYH3_k127_8369727_1 Arsenical pump membrane protein K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 593.0
PYH3_k127_8369727_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 542.0
PYH3_k127_8369727_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 415.0
PYH3_k127_8369727_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008677 253.0
PYH3_k127_8369727_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000002271 234.0
PYH3_k127_8369727_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.0000000000000000000000000000000000000000000000000000005657 202.0
PYH3_k127_8369727_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001236 183.0
PYH3_k127_8369727_8 AMP binding - - - 0.0000000000000000000000000000000000000000000000005077 186.0
PYH3_k127_8369727_9 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000004051 158.0
PYH3_k127_8431574_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.968e-195 620.0
PYH3_k127_8431574_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 379.0
PYH3_k127_8431574_2 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002665 284.0
PYH3_k127_8600984_0 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 438.0
PYH3_k127_8600984_1 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 362.0
PYH3_k127_8600984_10 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000004136 209.0
PYH3_k127_8600984_11 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000597 191.0
PYH3_k127_8600984_12 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000003197 179.0
PYH3_k127_8600984_13 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000009051 171.0
PYH3_k127_8600984_14 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000003828 173.0
PYH3_k127_8600984_16 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000006082 149.0
PYH3_k127_8600984_17 - - - - 0.0000000000000000000000000000000003953 143.0
PYH3_k127_8600984_18 Peptidase family M54 K06974 - - 0.0000000000000000000000000000001014 132.0
PYH3_k127_8600984_19 - - - - 0.00000000000000000000000000003389 125.0
PYH3_k127_8600984_2 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 348.0
PYH3_k127_8600984_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 321.0
PYH3_k127_8600984_4 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 330.0
PYH3_k127_8600984_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 299.0
PYH3_k127_8600984_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001131 274.0
PYH3_k127_8600984_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007917 263.0
PYH3_k127_8600984_8 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K17735 - 1.1.1.108,1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000001422 246.0
PYH3_k127_8600984_9 Fumarase C-terminus K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002494 233.0
PYH3_k127_8643705_0 Heat shock 70 kDa protein K04043 - - 2.045e-313 970.0
PYH3_k127_8643705_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 581.0
PYH3_k127_8643705_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 415.0
PYH3_k127_8643705_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 323.0
PYH3_k127_8643705_4 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH3_k127_8643705_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000298 152.0
PYH3_k127_8643705_6 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000007927 162.0
PYH3_k127_8643705_7 cellulase activity - - - 0.00000000000000001512 97.0
PYH3_k127_8725318_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 3.929e-288 906.0
PYH3_k127_8725318_1 Formate dehydrogenase iron-sulfur subunit K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007817 250.0
PYH3_k127_8725318_2 PFAM Molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000009473 209.0
PYH3_k127_8725318_3 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000003834 192.0
PYH3_k127_8725318_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000006924 133.0
PYH3_k127_8725318_5 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000009216 136.0
PYH3_k127_8725318_6 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000003788 125.0
PYH3_k127_8725318_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000008591 62.0
PYH3_k127_8725318_8 - - - - 0.00000819 53.0
PYH3_k127_8725318_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.0001674 47.0
PYH3_k127_8743374_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 564.0
PYH3_k127_8743374_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 512.0
PYH3_k127_8743374_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 380.0
PYH3_k127_8743374_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000002133 193.0
PYH3_k127_8743374_4 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000002027 179.0
PYH3_k127_8748557_0 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 469.0
PYH3_k127_8748557_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 405.0
PYH3_k127_8748557_2 PFAM Transketolase K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 376.0
PYH3_k127_8748557_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 326.0
PYH3_k127_8748557_4 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003384 257.0
PYH3_k127_8748557_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000002227 171.0
PYH3_k127_8748557_6 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000000008417 154.0
PYH3_k127_8748557_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003388 142.0
PYH3_k127_8748557_8 acetoacetate decarboxylase activity K01574 - 4.1.1.4 0.0000000000001539 71.0
PYH3_k127_8748557_9 Major Facilitator Superfamily K03535,K08194 - - 0.000000000001349 79.0
PYH3_k127_8795562_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 620.0
PYH3_k127_8795562_1 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 593.0
PYH3_k127_8795562_10 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000006345 185.0
PYH3_k127_8795562_11 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000005781 156.0
PYH3_k127_8795562_12 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000003972 148.0
PYH3_k127_8795562_13 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates - - - 0.00000000000000000000000000000003097 130.0
PYH3_k127_8795562_14 NADH-quinone oxidoreductase, E subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000000000000000003636 122.0
PYH3_k127_8795562_15 - - - - 0.00000000000000000000000000005702 117.0
PYH3_k127_8795562_16 cheY-homologous receiver domain - - - 0.000000000000000000000001064 109.0
PYH3_k127_8795562_17 PFAM response regulator receiver - - - 0.00000000000000000000002242 106.0
PYH3_k127_8795562_18 - - - - 0.000000000000000000000123 98.0
PYH3_k127_8795562_19 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000005337 96.0
PYH3_k127_8795562_2 Radical SAM superfamily K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 518.0
PYH3_k127_8795562_20 Glutamine amidotransferase class-I - - - 0.0000000000000000000005569 99.0
PYH3_k127_8795562_21 - - - - 0.000000000000000001787 87.0
PYH3_k127_8795562_23 GIY-YIG catalytic domain K07461 - - 0.00000000000000002447 83.0
PYH3_k127_8795562_24 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000002498 76.0
PYH3_k127_8795562_25 - - - - 0.0000000003595 61.0
PYH3_k127_8795562_26 - - - - 0.000000007808 61.0
PYH3_k127_8795562_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 427.0
PYH3_k127_8795562_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 387.0
PYH3_k127_8795562_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 376.0
PYH3_k127_8795562_6 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 311.0
PYH3_k127_8795562_7 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000003346 212.0
PYH3_k127_8795562_8 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K22338 - 1.17.1.11 0.000000000000000000000000000000000000000000000000000004262 198.0
PYH3_k127_8795562_9 PhoQ Sensor K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001239 207.0
PYH3_k127_8821988_0 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 458.0
PYH3_k127_8821988_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 338.0
PYH3_k127_8821988_10 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000001379 167.0
PYH3_k127_8821988_11 Glutaredoxin K03676,K04771 - 3.4.21.107 0.00000000000000000000000000000000001383 141.0
PYH3_k127_8821988_12 Transcriptional regulator - - - 0.0000000000000000000000000000113 127.0
PYH3_k127_8821988_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000001201 67.0
PYH3_k127_8821988_2 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 339.0
PYH3_k127_8821988_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 303.0
PYH3_k127_8821988_4 Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005567 241.0
PYH3_k127_8821988_5 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000002429 214.0
PYH3_k127_8821988_6 Peptide ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000005961 226.0
PYH3_k127_8821988_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000001692 193.0
PYH3_k127_8821988_8 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000005756 184.0
PYH3_k127_8821988_9 Transcriptional regulator, Crp Fnr family K10914,K21563 - - 0.000000000000000000000000000000000000000000000001818 184.0
PYH3_k127_8838012_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 347.0
PYH3_k127_8838012_1 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 336.0
PYH3_k127_8838012_2 KR domain - - - 0.000000000000000000000000000000000000000000000001339 184.0
PYH3_k127_8839435_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.99e-212 672.0
PYH3_k127_8839435_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 298.0
PYH3_k127_8840978_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.338e-228 715.0
PYH3_k127_8840978_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 447.0
PYH3_k127_8840978_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 281.0
PYH3_k127_8840978_3 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000001871 185.0
PYH3_k127_8840978_4 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000003021 158.0
PYH3_k127_8840978_5 MgtC family K07507 - - 0.00000000000000002124 83.0
PYH3_k127_8873019_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.136e-216 688.0
PYH3_k127_8873019_1 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 470.0
PYH3_k127_8873019_2 Poly A polymerase head domain K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 308.0
PYH3_k127_8873019_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 297.0
PYH3_k127_8873019_4 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000005006 186.0
PYH3_k127_8873019_5 PFAM Rubrerythrin - - - 0.000000003335 57.0
PYH3_k127_8880506_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.618e-218 685.0
PYH3_k127_8880506_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 464.0
PYH3_k127_8880506_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.00000002969 55.0
PYH3_k127_8888502_0 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 473.0
PYH3_k127_8888502_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 419.0
PYH3_k127_8888502_2 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 269.0
PYH3_k127_8888502_3 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000002821 179.0
PYH3_k127_8888502_4 PFAM short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000005436 180.0
PYH3_k127_8925923_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007135 282.0
PYH3_k127_8925923_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000004162 229.0
PYH3_k127_8925923_2 - - - - 0.0000000000000000008805 96.0
PYH3_k127_8925923_3 Domain of unknown function (DUF362) - - - 0.00000000001582 67.0
PYH3_k127_8925923_4 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.000000007847 58.0
PYH3_k127_8925923_5 Aldo/keto reductase family K07079 - - 0.000005871 52.0
PYH3_k127_8925923_6 Domain of unknown function (DUF362) - - - 0.0003267 46.0
PYH3_k127_8957919_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 444.0
PYH3_k127_8957919_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 360.0
PYH3_k127_8957919_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000006744 216.0
PYH3_k127_8957919_4 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000001303 151.0
PYH3_k127_8957919_5 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000166 122.0
PYH3_k127_8957919_6 Thioredoxin-like - - - 0.000000000000000000000000002454 128.0
PYH3_k127_9036259_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 8.405e-203 643.0
PYH3_k127_9036259_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 438.0
PYH3_k127_9036259_10 Putative Fe-S cluster - - - 0.000000000000005314 79.0
PYH3_k127_9036259_11 Altronate hydrolase K01685 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.7 0.000000000000149 76.0
PYH3_k127_9036259_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 418.0
PYH3_k127_9036259_3 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 330.0
PYH3_k127_9036259_4 HIT domain K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000001643 213.0
PYH3_k127_9036259_5 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000000000000003945 147.0
PYH3_k127_9036259_6 - - - - 0.0000000000000000000000000000007873 126.0
PYH3_k127_9036259_7 Preprotein translocase subunit K03210 - - 0.0000000000000000001755 93.0
PYH3_k127_9036259_8 Putative zinc ribbon domain - - - 0.000000000000000009071 86.0
PYH3_k127_9036259_9 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.00000000000000001238 84.0
PYH3_k127_904270_0 fructose-1,6-bisphosphatase K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 384.0
PYH3_k127_904270_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 303.0
PYH3_k127_904270_2 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 297.0
PYH3_k127_904270_3 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000127 166.0
PYH3_k127_904270_4 Belongs to the UPF0149 family K07039 - - 0.00001102 49.0
PYH3_k127_9047838_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 325.0
PYH3_k127_9047838_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000006334 246.0
PYH3_k127_9047838_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000007573 226.0
PYH3_k127_9047838_3 - - - - 0.0000000000000000000000000000000000001648 144.0
PYH3_k127_9047838_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000004338 96.0
PYH3_k127_9047838_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000006764 64.0
PYH3_k127_9057728_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 578.0
PYH3_k127_9057728_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 479.0
PYH3_k127_9057728_10 positive regulation of type IV pilus biogenesis K07343 - - 0.0005303 44.0
PYH3_k127_9057728_2 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004577 251.0
PYH3_k127_9057728_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001216 252.0
PYH3_k127_9057728_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
PYH3_k127_9057728_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000004719 242.0
PYH3_k127_9057728_6 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003259 226.0
PYH3_k127_9057728_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000001332 201.0
PYH3_k127_9057728_8 PFAM Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000002673 115.0
PYH3_k127_9057728_9 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000001799 103.0
PYH3_k127_9057784_0 PFAM DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000001159 220.0
PYH3_k127_9057784_1 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000002682 228.0
PYH3_k127_9057784_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000009559 208.0
PYH3_k127_9057784_3 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00004389 46.0
PYH3_k127_9057784_4 carnitine dehydratase K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.0009222 42.0
PYH3_k127_9193144_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002354 283.0
PYH3_k127_9193144_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003523 246.0
PYH3_k127_9193144_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000005388 213.0
PYH3_k127_9193144_3 AIR synthase related protein, C-terminal domain - - - 0.000007562 48.0
PYH3_k127_9326459_0 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 355.0
PYH3_k127_9326459_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 239.0
PYH3_k127_9326459_2 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000103 234.0
PYH3_k127_9326459_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000002023 219.0
PYH3_k127_9326459_4 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000001111 211.0
PYH3_k127_9326459_5 phosphoribosyl-AMP cyclohydrolase activity K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000002232 145.0
PYH3_k127_9326459_6 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000001222 139.0
PYH3_k127_9326459_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000002103 138.0
PYH3_k127_9326459_8 heat shock protein DnaJ domain protein K03686,K05516 - - 0.0000000000000000000000000000002497 131.0
PYH3_k127_93852_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 357.0
PYH3_k127_93852_1 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 344.0
PYH3_k127_93852_2 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 315.0
PYH3_k127_93852_3 sh3 domain protein - - - 0.000000000000000000000000000000000000000000000000000718 202.0
PYH3_k127_93852_4 PFAM GDSL-like Lipase Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000308 188.0
PYH3_k127_93852_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000006686 133.0
PYH3_k127_93852_6 Protein of unknown function (DUF2851) - - - 0.0000000000000000000000000000005878 134.0
PYH3_k127_944729_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.119e-243 761.0
PYH3_k127_944729_1 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 316.0
PYH3_k127_944729_2 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001467 240.0
PYH3_k127_944729_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000004209 229.0
PYH3_k127_944729_4 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000004894 222.0
PYH3_k127_944729_5 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000001964 201.0
PYH3_k127_944729_6 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000009686 173.0
PYH3_k127_944729_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000001289 174.0
PYH3_k127_944729_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000008199 141.0
PYH3_k127_955871_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000003946 212.0
PYH3_k127_955871_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000004758 178.0
PYH3_k127_9578750_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 8.968e-295 922.0
PYH3_k127_9578750_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.84e-203 641.0
PYH3_k127_9578750_10 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000265 199.0
PYH3_k127_9578750_11 - - - - 0.000000000000000000000000000000000001199 142.0
PYH3_k127_9578750_12 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000000000000000004207 133.0
PYH3_k127_9578750_13 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000004666 128.0
PYH3_k127_9578750_14 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000002687 114.0
PYH3_k127_9578750_15 - - - - 0.0000000000000000000022 96.0
PYH3_k127_9578750_16 Trypsin-like serine protease - - - 0.0000000000000000003989 92.0
PYH3_k127_9578750_17 Domain of unknown function (DU1801) - - - 0.0000000000000002271 83.0
PYH3_k127_9578750_2 Terminase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 580.0
PYH3_k127_9578750_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 526.0
PYH3_k127_9578750_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 512.0
PYH3_k127_9578750_5 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 467.0
PYH3_k127_9578750_6 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 419.0
PYH3_k127_9578750_7 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 356.0
PYH3_k127_9578750_8 cobalamin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000001434 247.0
PYH3_k127_9578750_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000002667 197.0
PYH3_k127_9605379_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 335.0
PYH3_k127_9605379_1 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 311.0
PYH3_k127_9605379_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000491 226.0
PYH3_k127_9605379_3 denitrification pathway - - - 0.0000000000000000000000000000000000000000000001108 177.0
PYH3_k127_9605379_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000009194 151.0
PYH3_k127_9605379_5 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000000000002059 149.0
PYH3_k127_9605379_6 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000187 137.0
PYH3_k127_9605379_7 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.0000000000000000000000000000000004091 139.0
PYH3_k127_9605379_8 Belongs to the UPF0434 family - - - 0.000000000000000007103 85.0
PYH3_k127_9613956_0 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 531.0
PYH3_k127_9613956_1 PFAM GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000000001762 176.0
PYH3_k127_9613956_2 PAAR repeat-containing protein - - - 0.000000000000000000000000000000000000007477 147.0
PYH3_k127_9613956_3 PFAM Phage tail protein (Tail_P2_I) - - - 0.00000000000000000000000001681 115.0
PYH3_k127_9701765_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 332.0
PYH3_k127_9701765_1 PFAM glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000000000000000000001224 251.0
PYH3_k127_9701765_10 - K01385 - 3.4.23.42 0.0001907 54.0
PYH3_k127_9701765_2 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000001118 190.0
PYH3_k127_9701765_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000604 177.0
PYH3_k127_9701765_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000004025 121.0
PYH3_k127_9701765_5 Protein of unknown function (DUF3343) - - - 0.0000000000000000000002989 101.0
PYH3_k127_9701765_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000002313 89.0
PYH3_k127_9701765_7 - K07112 - - 0.00000003182 65.0
PYH3_k127_9701765_8 PFAM Flavodoxin K03809 - 1.6.5.2 0.0000008717 57.0
PYH3_k127_9701765_9 Protein of unknown function (DUF3343) - - - 0.000002467 50.0
PYH3_k127_971_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 621.0
PYH3_k127_971_1 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 592.0
PYH3_k127_971_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 448.0
PYH3_k127_971_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 292.0
PYH3_k127_971_4 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007185 297.0
PYH3_k127_971_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009137 264.0
PYH3_k127_971_6 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004043 229.0
PYH3_k127_971_7 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000001095 126.0
PYH3_k127_971_8 Response regulator receiver domain K02658 - - 0.0000006942 58.0
PYH3_k127_9739357_0 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 408.0
PYH3_k127_9739357_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003046 259.0
PYH3_k127_9739357_2 Ecdysteroid kinase - - - 0.000000000000000000000000000000000000000000000000000137 200.0
PYH3_k127_9739357_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000002518 185.0