Overview

ID MAG03295
Name REGS1_bin.25
Sample SMP0079
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Gallionellaceae
Genus Sideroxyarcus
Species
Assembly information
Completeness (%) 74.18
Contamination (%) 0.36
GC content (%) 56.0
N50 (bp) 9,847
Genome size (bp) 2,170,819

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2161

Gene name Description KEGG GOs EC E-value Score Sequence
REGS1_k127_1003814_0 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0 1134.0
REGS1_k127_1003814_1 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.827e-279 863.0
REGS1_k127_1003814_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000427 229.0
REGS1_k127_1107464_0 May be involved in recombinational repair of damaged DNA K03631 - - 3.107e-272 845.0
REGS1_k127_1107464_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 4.329e-204 638.0
REGS1_k127_1107464_2 Winged helix-turn-helix transcription repressor, HrcA DNA-binding K03705 - - 3.463e-194 618.0
REGS1_k127_1107464_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 460.0
REGS1_k127_1107464_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 445.0
REGS1_k127_1107464_5 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 281.0
REGS1_k127_1107464_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000000000000004708 166.0
REGS1_k127_1107464_7 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000008266 88.0
REGS1_k127_1107464_8 glycosyl - - - 0.0000000000000002334 80.0
REGS1_k127_1107464_9 Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA) K19222 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901576,GO:1901661,GO:1901663 3.1.2.28 0.000000001427 65.0
REGS1_k127_1139451_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 554.0
REGS1_k127_1139451_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 378.0
REGS1_k127_1139451_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 358.0
REGS1_k127_1139451_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 357.0
REGS1_k127_1139451_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 338.0
REGS1_k127_1139451_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000001248 207.0
REGS1_k127_1139451_6 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000002189 62.0
REGS1_k127_1139451_7 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000005382 69.0
REGS1_k127_1169432_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1033.0
REGS1_k127_1169432_1 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000000006775 235.0
REGS1_k127_1169432_2 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.0000000000000000000000000000000000000000000000000000000000001067 213.0
REGS1_k127_1169432_3 TIGRFAM ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.00000000000000000000000000000000000000000000000000000000006721 207.0
REGS1_k127_1169432_4 Iron-sulphur cluster assembly - - - 0.000000000000000000000000000001251 122.0
REGS1_k127_1169432_5 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000002904 111.0
REGS1_k127_1169432_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000005091 65.0
REGS1_k127_1173648_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 1.454e-264 819.0
REGS1_k127_1173648_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.647e-243 758.0
REGS1_k127_1173648_2 Nitronate monooxygenase K00459 - 1.13.12.16 9.157e-235 730.0
REGS1_k127_1173648_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 519.0
REGS1_k127_1173648_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 349.0
REGS1_k127_1173648_5 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 350.0
REGS1_k127_1173648_6 - - - - 0.000000000000000000000000000000000000000000000000000004422 194.0
REGS1_k127_1173648_7 - - - - 0.000000000000000000000000000000000000000004155 156.0
REGS1_k127_1173648_8 - - - - 0.00000000000000000000000000000000001929 141.0
REGS1_k127_1175500_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 514.0
REGS1_k127_1175500_1 Ribosomal protein L9, N-terminal domain K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000921 250.0
REGS1_k127_1175500_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000000006784 172.0
REGS1_k127_1175500_3 DNA replication, synthesis of RNA primer K02686 - - 0.0000000000000000000000000002379 114.0
REGS1_k127_1180816_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1222.0
REGS1_k127_1180816_1 Glutamine synthetase, catalytic domain K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.699e-304 934.0
REGS1_k127_1180816_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 8.495e-212 662.0
REGS1_k127_1180816_3 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 593.0
REGS1_k127_1180816_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 396.0
REGS1_k127_1180816_5 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
REGS1_k127_1180816_6 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
REGS1_k127_1180816_7 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000000000003771 147.0
REGS1_k127_1180816_9 Protein of unknown function (DUF1289) K06938 - - 0.00000000000000000001704 96.0
REGS1_k127_1183743_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.813e-281 871.0
REGS1_k127_1183743_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.962e-253 782.0
REGS1_k127_1183743_2 Cytochrome b(N-terminal)/b6/petB K00412 - - 6.58e-234 727.0
REGS1_k127_1183743_3 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 286.0
REGS1_k127_1183743_4 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008639 272.0
REGS1_k127_1183743_5 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000002856 158.0
REGS1_k127_1183743_6 methyltransferase - - - 0.0000004144 53.0
REGS1_k127_1186381_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1351.0
REGS1_k127_1186381_1 PFAM ATP-binding region ATPase domain protein - - - 1.132e-210 670.0
REGS1_k127_1186381_10 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000825 284.0
REGS1_k127_1186381_11 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003745 259.0
REGS1_k127_1186381_12 Tetratricopeptide repeat K12284 - - 0.000000000000000000000000000000000000000000000000008043 187.0
REGS1_k127_1186381_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 4.333e-208 651.0
REGS1_k127_1186381_3 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 589.0
REGS1_k127_1186381_4 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 522.0
REGS1_k127_1186381_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 417.0
REGS1_k127_1186381_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 330.0
REGS1_k127_1186381_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 325.0
REGS1_k127_1186381_8 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 320.0
REGS1_k127_1186381_9 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 310.0
REGS1_k127_1203373_0 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 606.0
REGS1_k127_1203373_1 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 434.0
REGS1_k127_1203373_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 376.0
REGS1_k127_1203373_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000000000001452 162.0
REGS1_k127_1203373_4 Planctomycete cytochrome C - - - 0.00000000000000000000005047 103.0
REGS1_k127_1203373_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000003064 61.0
REGS1_k127_1204718_0 Acyl-CoA dehydrogenase, N-terminal domain K06445 - - 0.0 1319.0
REGS1_k127_1204718_1 TIGRFAM efflux transporter, RND family, MFP subunit K07798,K15727 - - 4.135e-234 743.0
REGS1_k127_1204718_2 PFAM outer membrane efflux protein - - - 5.942e-207 649.0
REGS1_k127_1204718_3 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 443.0
REGS1_k127_1204718_4 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 346.0
REGS1_k127_1204718_5 - - - - 0.000000000000000000000000000000000000000000008486 166.0
REGS1_k127_1204718_6 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000003247 121.0
REGS1_k127_1204718_7 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000005312 83.0
REGS1_k127_1212616_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1299.0
REGS1_k127_1212616_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1148.0
REGS1_k127_1212616_10 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 524.0
REGS1_k127_1212616_11 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 523.0
REGS1_k127_1212616_12 PFAM TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 457.0
REGS1_k127_1212616_13 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 394.0
REGS1_k127_1212616_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 360.0
REGS1_k127_1212616_15 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
REGS1_k127_1212616_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 321.0
REGS1_k127_1212616_17 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 323.0
REGS1_k127_1212616_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 310.0
REGS1_k127_1212616_19 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 309.0
REGS1_k127_1212616_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.433e-297 916.0
REGS1_k127_1212616_20 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 293.0
REGS1_k127_1212616_21 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 291.0
REGS1_k127_1212616_22 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 289.0
REGS1_k127_1212616_23 PFAM cytochrome K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003554 279.0
REGS1_k127_1212616_24 transport system periplasmic component K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000415 267.0
REGS1_k127_1212616_25 Histidine kinase K03406,K05875,K07647 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000002947 243.0
REGS1_k127_1212616_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000008848 172.0
REGS1_k127_1212616_27 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000000000000000004243 160.0
REGS1_k127_1212616_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 7.133e-275 850.0
REGS1_k127_1212616_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.514e-265 818.0
REGS1_k127_1212616_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.157e-264 819.0
REGS1_k127_1212616_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.915e-251 781.0
REGS1_k127_1212616_7 Ammonium Transporter Family K03320,K06580 - - 3.121e-233 724.0
REGS1_k127_1212616_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.416e-204 638.0
REGS1_k127_1212616_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 571.0
REGS1_k127_1226262_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 599.0
REGS1_k127_1226262_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 521.0
REGS1_k127_1226262_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 513.0
REGS1_k127_1226262_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 386.0
REGS1_k127_1226262_4 PFAM type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 311.0
REGS1_k127_1226262_5 SMART Prolyl 4-hydroxylase alpha subunit K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 297.0
REGS1_k127_1226262_6 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 289.0
REGS1_k127_1226262_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004826 275.0
REGS1_k127_1226262_8 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000004835 254.0
REGS1_k127_1226262_9 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000000000000000000000000005704 164.0
REGS1_k127_1300791_0 Iron-containing alcohol dehydrogenase K08325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 582.0
REGS1_k127_1300791_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 505.0
REGS1_k127_1300791_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 351.0
REGS1_k127_1300791_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006968 275.0
REGS1_k127_1300791_4 - - - - 0.0000000000000000000000000000000000000000000000000000000002872 211.0
REGS1_k127_1304123_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 4.072e-265 863.0
REGS1_k127_1304123_1 Surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 512.0
REGS1_k127_1304123_2 SMART Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 319.0
REGS1_k127_1304123_3 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.0000000000000000000000000000000000000000000000000000000001332 207.0
REGS1_k127_1304123_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000001386 195.0
REGS1_k127_1304123_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000000000008961 175.0
REGS1_k127_1304123_6 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000000000000000000000000000000007257 170.0
REGS1_k127_1304123_7 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000005012 68.0
REGS1_k127_1337094_0 helix_turn_helix gluconate operon transcriptional repressor - - - 1.274e-274 848.0
REGS1_k127_1337094_1 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 2.095e-254 791.0
REGS1_k127_1337094_2 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 558.0
REGS1_k127_1337094_3 PFAM Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000003246 210.0
REGS1_k127_1337094_4 - - - - 0.000000000000000000000000000000000000000000000007222 173.0
REGS1_k127_1337094_5 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000000000000000000002953 159.0
REGS1_k127_1337094_6 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000003181 81.0
REGS1_k127_1337094_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000652 66.0
REGS1_k127_1367702_0 Conserved repeat domain K12287 - - 3.558e-232 767.0
REGS1_k127_1367702_1 Pilus assembly protein K12279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 444.0
REGS1_k127_1367702_2 PFAM type II and III secretion system protein K02453,K12282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 295.0
REGS1_k127_1367702_3 carbon utilization K12280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 293.0
REGS1_k127_1367702_4 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000901 260.0
REGS1_k127_1367702_5 Prokaryotic N-terminal methylation motif K12285 - - 0.0000000000000000000000000000000000000000000000000000000003513 216.0
REGS1_k127_1367702_6 Prokaryotic N-terminal methylation motif K10926 - - 0.00000000000000000000000000000000000000000000000000001015 194.0
REGS1_k127_1367702_7 type IV pilus modification protein PilV K10927 - - 0.0000000000000000000000000000000000000000000000000001501 192.0
REGS1_k127_1367702_8 Pilus assembly protein PilX K12286 - - 0.000000000000000000003164 98.0
REGS1_k127_1367702_9 - K12281 - - 0.0000000001313 72.0
REGS1_k127_136981_0 HELICc2 K03722 - 3.6.4.12 2.054e-209 656.0
REGS1_k127_136981_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 351.0
REGS1_k127_136981_2 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 323.0
REGS1_k127_136981_3 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 322.0
REGS1_k127_136981_4 ATPase MipZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 306.0
REGS1_k127_136981_5 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006703 260.0
REGS1_k127_136981_6 - - - - 0.0000000001582 70.0
REGS1_k127_136981_7 Plasmid stabilization system - - - 0.0000003934 57.0
REGS1_k127_136981_8 HELICc2 K03722 - 3.6.4.12 0.00006046 46.0
REGS1_k127_1382813_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.26e-262 816.0
REGS1_k127_1382813_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 563.0
REGS1_k127_1382813_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000002176 205.0
REGS1_k127_1382813_11 related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000001543 192.0
REGS1_k127_1382813_12 Tautomerase enzyme - - - 0.000000000000000000000000000000000000000000000000002649 184.0
REGS1_k127_1382813_13 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000009368 152.0
REGS1_k127_1382813_14 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000319 151.0
REGS1_k127_1382813_15 PFAM helix-turn-helix domain protein K07729 - - 0.0000000000000003374 79.0
REGS1_k127_1382813_16 - - - - 0.000001829 59.0
REGS1_k127_1382813_2 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 554.0
REGS1_k127_1382813_3 ATP synthase K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 376.0
REGS1_k127_1382813_4 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007322 276.0
REGS1_k127_1382813_5 KR domain K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001137 271.0
REGS1_k127_1382813_6 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002049 255.0
REGS1_k127_1382813_7 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003525 243.0
REGS1_k127_1382813_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004398 226.0
REGS1_k127_1382813_9 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000001422 219.0
REGS1_k127_1403073_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.016e-262 809.0
REGS1_k127_1403073_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 8.577e-194 606.0
REGS1_k127_1403073_2 Appr-1-p processing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 305.0
REGS1_k127_1403073_3 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 296.0
REGS1_k127_1403073_4 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 295.0
REGS1_k127_1403073_5 DJ-1/PfpI family K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005095 277.0
REGS1_k127_1403073_6 SMART phosphoesterase PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004183 273.0
REGS1_k127_1403073_7 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000007122 183.0
REGS1_k127_1403073_8 Protein of unknown function (DUF2798) - - - 0.00000000000005977 74.0
REGS1_k127_1403073_9 Thioredoxin K03671 - - 0.0003328 44.0
REGS1_k127_1417705_0 diguanylate cyclase K13069 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 308.0
REGS1_k127_1417705_1 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 293.0
REGS1_k127_1417705_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000004259 89.0
REGS1_k127_1417705_3 Putative addiction module component - - - 0.000000004553 60.0
REGS1_k127_1441280_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.397e-242 762.0
REGS1_k127_1441280_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 494.0
REGS1_k127_1441280_2 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000000000008811 162.0
REGS1_k127_1455919_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1118.0
REGS1_k127_1462161_0 Protein of unknown function - - - 0.0 1375.0
REGS1_k127_1462161_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1364.0
REGS1_k127_1462161_10 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 407.0
REGS1_k127_1462161_11 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001093 258.0
REGS1_k127_1462161_12 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008073 256.0
REGS1_k127_1462161_13 PFAM Ig domain protein group 2 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000002941 236.0
REGS1_k127_1462161_14 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000001266 186.0
REGS1_k127_1462161_15 oxygen carrier activity K07216 - - 0.0000000000000000000000000000000000000000007 161.0
REGS1_k127_1462161_16 Zinc-finger domain - - - 0.00000000000000000000000000000000003769 134.0
REGS1_k127_1462161_17 Protein of unknown function (DUF3617) - - - 0.000000000000000000000001247 108.0
REGS1_k127_1462161_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000009011 76.0
REGS1_k127_1462161_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1332.0
REGS1_k127_1462161_3 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 6.007e-290 894.0
REGS1_k127_1462161_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 9.818e-279 863.0
REGS1_k127_1462161_5 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 3.706e-229 715.0
REGS1_k127_1462161_6 Galactose oxidase, central domain - - - 4.085e-195 653.0
REGS1_k127_1462161_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 599.0
REGS1_k127_1462161_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 542.0
REGS1_k127_1462161_9 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 521.0
REGS1_k127_14657_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 1.563e-205 643.0
REGS1_k127_14657_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 525.0
REGS1_k127_14657_2 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 400.0
REGS1_k127_14657_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 313.0
REGS1_k127_14657_4 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 288.0
REGS1_k127_14657_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000006582 108.0
REGS1_k127_14657_8 Nitrogenase component 1 type Oxidoreductase K02592 - - 0.00004131 49.0
REGS1_k127_1478427_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.401e-265 820.0
REGS1_k127_1478427_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 569.0
REGS1_k127_1478427_10 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 336.0
REGS1_k127_1478427_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004658 281.0
REGS1_k127_1478427_12 Protein of unknown function (DUF560) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006621 252.0
REGS1_k127_1478427_13 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000003177 169.0
REGS1_k127_1478427_14 KTSC domain - - - 0.000000000000000000000000000000000000000000006771 164.0
REGS1_k127_1478427_15 DNA recombination K15482,K20345 - - 0.00000000000000000000000000000000003506 156.0
REGS1_k127_1478427_16 PFAM FecR protein - - - 0.000000000000000000000000000007762 129.0
REGS1_k127_1478427_17 SMART Cold shock protein K03704 - - 0.0000000000000000000000000000143 120.0
REGS1_k127_1478427_18 KTSC domain - - - 0.000000000000000000000001739 106.0
REGS1_k127_1478427_19 - - - - 0.00000000000004525 77.0
REGS1_k127_1478427_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 580.0
REGS1_k127_1478427_20 PFAM SMP-30 Gluconolaconase - - - 0.0000000001639 72.0
REGS1_k127_1478427_21 - - - - 0.000000003551 61.0
REGS1_k127_1478427_3 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 515.0
REGS1_k127_1478427_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 517.0
REGS1_k127_1478427_5 Major facilitator superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 493.0
REGS1_k127_1478427_6 NADPH quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 458.0
REGS1_k127_1478427_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 368.0
REGS1_k127_1478427_8 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 337.0
REGS1_k127_1478427_9 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 332.0
REGS1_k127_1486191_0 Nacht domain - - - 0.0 2669.0
REGS1_k127_1486191_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1260.0
REGS1_k127_1486191_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
REGS1_k127_1486191_11 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001952 270.0
REGS1_k127_1486191_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000001712 207.0
REGS1_k127_1486191_13 TIGRFAM Addiction module toxin, RelE StbE K06218 - - 0.000000000000000000000000000000000000000000000005192 172.0
REGS1_k127_1486191_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000701 146.0
REGS1_k127_1486191_15 ParE-like toxin of type II bacterial toxin-antitoxin system - - - 0.0000000000000000000000000000000001136 135.0
REGS1_k127_1486191_16 AhpC/TSA family - - - 0.000000000000000000000000000007886 122.0
REGS1_k127_1486191_17 Antitoxin component of a toxin-antitoxin (TA) module K18923 - - 0.00000000000000000000000002129 110.0
REGS1_k127_1486191_19 Transcriptional regulator K18304 - - 0.000000000000000000001502 99.0
REGS1_k127_1486191_2 UvrD-like helicase C-terminal domain - - - 1.306e-257 807.0
REGS1_k127_1486191_20 AhpC/TSA family - - - 0.000000000000000000009509 93.0
REGS1_k127_1486191_21 Protein of unknown function (DUF2283) - - - 0.0000000000000000001348 89.0
REGS1_k127_1486191_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000008654 88.0
REGS1_k127_1486191_23 Transcriptional regulator - - - 0.000000000000000005576 85.0
REGS1_k127_1486191_24 Helix-turn-helix domain - - - 0.0000000000000002177 80.0
REGS1_k127_1486191_27 Helix-turn-helix XRE-family like proteins - - - 0.0000000000002376 73.0
REGS1_k127_1486191_28 ParD-like antitoxin of type II bacterial toxin-antitoxin system - - - 0.000000000005811 68.0
REGS1_k127_1486191_29 Transmembrane anti-sigma factor - - - 0.00000000004487 66.0
REGS1_k127_1486191_3 membrane organization K20543 - - 2.74e-236 735.0
REGS1_k127_1486191_30 von willebrand factor, type A K20276 - - 0.0000000001258 76.0
REGS1_k127_1486191_32 Excisionase-like protein - - - 0.00001898 52.0
REGS1_k127_1486191_4 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 477.0
REGS1_k127_1486191_5 Protein conserved in bacteria K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 458.0
REGS1_k127_1486191_6 Domain of unknown function(DUF2779) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 430.0
REGS1_k127_1486191_7 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 415.0
REGS1_k127_1486191_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 354.0
REGS1_k127_1486191_9 PFAM integrase family protein K07357,K07358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 347.0
REGS1_k127_1502439_0 Sigma-70 factor, region 1.2 K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 458.0
REGS1_k127_1502439_1 Glutathione S-transferase, C-terminal domain K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 386.0
REGS1_k127_1502439_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000008395 229.0
REGS1_k127_1502439_3 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000000000000000002779 228.0
REGS1_k127_1544025_0 Aminotransferase class-III K01845 - 5.4.3.8 1.017e-247 767.0
REGS1_k127_1544025_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 524.0
REGS1_k127_1544025_10 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000004271 163.0
REGS1_k127_1544025_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 460.0
REGS1_k127_1544025_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 449.0
REGS1_k127_1544025_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 439.0
REGS1_k127_1544025_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
REGS1_k127_1544025_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 337.0
REGS1_k127_1544025_7 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 321.0
REGS1_k127_1544025_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 289.0
REGS1_k127_1544025_9 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002345 279.0
REGS1_k127_1546716_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0 1023.0
REGS1_k127_1546716_1 NeuB family K03856 - 2.5.1.54 7.136e-213 662.0
REGS1_k127_1546716_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 475.0
REGS1_k127_1546716_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 357.0
REGS1_k127_1546716_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000002416 213.0
REGS1_k127_1550392_0 belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 3.273e-214 676.0
REGS1_k127_1550392_1 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 304.0
REGS1_k127_1550392_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 259.0
REGS1_k127_1550392_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000002656 215.0
REGS1_k127_1550392_4 - - - - 0.000000000000000003109 89.0
REGS1_k127_1578307_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.882e-264 816.0
REGS1_k127_1578307_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.707e-211 660.0
REGS1_k127_1578307_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 353.0
REGS1_k127_1578307_3 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000000001083 225.0
REGS1_k127_1578307_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000000001347 186.0
REGS1_k127_1578307_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000002491 158.0
REGS1_k127_1642461_0 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 5.512e-214 669.0
REGS1_k127_1642461_1 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 487.0
REGS1_k127_1642461_2 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 421.0
REGS1_k127_1642461_3 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 405.0
REGS1_k127_1642461_4 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000000000001185 152.0
REGS1_k127_1642461_5 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000000000001704 152.0
REGS1_k127_1642461_6 dehydratase - - - 0.000000000000000000000000000000000002188 147.0
REGS1_k127_1642461_7 AsmA family K07289 - - 0.00000000000000000000000001052 112.0
REGS1_k127_1642461_8 - - - - 0.00000000108 63.0
REGS1_k127_1653037_0 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 4.129e-232 722.0
REGS1_k127_1653037_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 376.0
REGS1_k127_1653037_2 PFAM Type II secretion system F domain K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000001421 221.0
REGS1_k127_1653037_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000000000000000000009692 162.0
REGS1_k127_1653037_4 - - - - 0.0000000000000000000000000000000000000000009804 166.0
REGS1_k127_1653037_5 TonB dependent receptor - - - 0.000000000000000000000004954 110.0
REGS1_k127_1653037_6 - K18829 - - 0.000000000000000000003779 95.0
REGS1_k127_1695946_0 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 390.0
REGS1_k127_1695946_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 323.0
REGS1_k127_1695946_2 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 308.0
REGS1_k127_1712892_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1840.0
REGS1_k127_1712892_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0 1197.0
REGS1_k127_1712892_10 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 454.0
REGS1_k127_1712892_11 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 285.0
REGS1_k127_1712892_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000008324 199.0
REGS1_k127_1712892_2 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0 1101.0
REGS1_k127_1712892_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1041.0
REGS1_k127_1712892_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.585e-293 903.0
REGS1_k127_1712892_5 Diguanylate cyclase - - - 1.788e-243 793.0
REGS1_k127_1712892_6 AFG1-like ATPase K06916 - - 9.333e-198 620.0
REGS1_k127_1712892_7 FIST_C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 593.0
REGS1_k127_1712892_8 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 597.0
REGS1_k127_1712892_9 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 481.0
REGS1_k127_1721269_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 6.717e-319 985.0
REGS1_k127_1721269_1 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
REGS1_k127_1721269_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000005013 209.0
REGS1_k127_1721269_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000698 185.0
REGS1_k127_1721269_6 Domain of unknown function (DUF4287) - - - 0.0000000000000000000000000234 110.0
REGS1_k127_1721269_7 FeoA K04758 - - 0.000000000000000000002507 98.0
REGS1_k127_1721269_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0002146 51.0
REGS1_k127_1736555_0 MacB-like periplasmic core domain K02004 - - 8.283e-225 705.0
REGS1_k127_1736555_1 MacB-like periplasmic core domain K02004 - - 8.658e-225 700.0
REGS1_k127_1736555_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 608.0
REGS1_k127_1736555_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 440.0
REGS1_k127_1736555_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 400.0
REGS1_k127_1736555_5 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 316.0
REGS1_k127_1736555_6 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022 - - 0.0000000000000000000000000000000000000000000001946 172.0
REGS1_k127_1737426_0 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 0.0 1043.0
REGS1_k127_1737426_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.591e-278 860.0
REGS1_k127_1737426_10 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000000000000000003225 144.0
REGS1_k127_1737426_11 Nucleotidyltransferase domain - - - 0.000000000000000000000000000000000001369 142.0
REGS1_k127_1737426_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.926e-213 662.0
REGS1_k127_1737426_3 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 548.0
REGS1_k127_1737426_4 PFAM permease YjgP YjgQ family protein K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 513.0
REGS1_k127_1737426_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 291.0
REGS1_k127_1737426_6 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 286.0
REGS1_k127_1737426_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003573 271.0
REGS1_k127_1737426_8 PFAM DNA polymerase III chi subunit HolC K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000003 240.0
REGS1_k127_1737426_9 nucleotidyltransferase substrate binding protein, HI0074 family - - - 0.00000000000000000000000000000000000000000000000000000000007372 207.0
REGS1_k127_1744808_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 8.829e-305 942.0
REGS1_k127_1744808_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 589.0
REGS1_k127_1744808_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009867 264.0
REGS1_k127_1744808_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000000000006752 234.0
REGS1_k127_1744808_4 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000000000000000000000000000004185 201.0
REGS1_k127_1744808_5 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000001436 198.0
REGS1_k127_1744808_6 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000002724 171.0
REGS1_k127_180993_0 Hsp90 protein K04079 - - 0.0 1086.0
REGS1_k127_180993_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1044.0
REGS1_k127_180993_2 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 5.924e-264 819.0
REGS1_k127_180993_3 SMART GGDEF domain containing protein - - - 1.45e-262 819.0
REGS1_k127_180993_4 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 502.0
REGS1_k127_180993_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 473.0
REGS1_k127_180993_6 elongation factor Tu domain 2 protein K06207 - - 0.00000000000000000000000000000002513 126.0
REGS1_k127_1839100_0 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 611.0
REGS1_k127_1839100_1 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 326.0
REGS1_k127_1839100_2 chlorophyll binding K02690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003109 270.0
REGS1_k127_1839100_3 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000004526 169.0
REGS1_k127_1839100_4 Protein of unknown function (DUF2288) - - - 0.00000000000000000000000000000000000000001543 154.0
REGS1_k127_1839100_5 Plasmid stabilization system - - - 0.00000000000000000001428 95.0
REGS1_k127_1844710_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.577e-276 880.0
REGS1_k127_1844710_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 5.684e-200 625.0
REGS1_k127_1844710_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 595.0
REGS1_k127_1844710_3 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000001095 132.0
REGS1_k127_1844710_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000287 78.0
REGS1_k127_1845667_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1442.0
REGS1_k127_1845667_1 metal-dependent phosphohydrolase HD sub domain - - - 1.489e-271 844.0
REGS1_k127_1845667_2 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 398.0
REGS1_k127_1845667_3 Prokaryotic N-terminal methylation motif K02650 - - 0.00000000000000000000000000158 114.0
REGS1_k127_1858946_0 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 0.0 1514.0
REGS1_k127_1858946_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 577.0
REGS1_k127_1858946_2 Protein of unknown function (DUF1016) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 570.0
REGS1_k127_1858946_3 Putative phage abortive infection protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000241 277.0
REGS1_k127_1858946_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001164 250.0
REGS1_k127_1858946_5 - - - - 0.000000000000000000000000000000000000000002898 161.0
REGS1_k127_1858946_6 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.000000000000000002258 85.0
REGS1_k127_194126_0 SMC domain protein - - - 0.0 1394.0
REGS1_k127_194126_1 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 3.23e-297 915.0
REGS1_k127_194126_2 membrane - - - 1.702e-204 644.0
REGS1_k127_194126_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 606.0
REGS1_k127_194126_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 550.0
REGS1_k127_194126_5 - - - - 0.0000000000000000000000000000000000000000000000000000000001203 211.0
REGS1_k127_194126_6 Protein of unknown function C-terminus (DUF2399) - - - 0.00000000000000000000000000000000000000000000007544 184.0
REGS1_k127_194126_7 DHH family K07462 - - 0.00000000000000000000000000000000000005388 142.0
REGS1_k127_195348_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.125e-281 868.0
REGS1_k127_195348_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 1.575e-233 724.0
REGS1_k127_195348_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 597.0
REGS1_k127_195348_3 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 475.0
REGS1_k127_195348_4 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
REGS1_k127_195348_5 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002887 276.0
REGS1_k127_195348_6 RecX family K03565 - - 0.000000000000000000000000000000000000000000000000000000000004101 213.0
REGS1_k127_195348_7 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000005873 187.0
REGS1_k127_1993445_0 PFAM CHAD domain containing protein - - - 3.402e-253 787.0
REGS1_k127_1993445_1 HI0933-like protein K07007 - - 5.126e-202 636.0
REGS1_k127_1993445_2 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 382.0
REGS1_k127_1993445_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 374.0
REGS1_k127_1993445_4 LemA Family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 367.0
REGS1_k127_1993445_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002293 275.0
REGS1_k127_1993445_6 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000000000000001152 227.0
REGS1_k127_2016011_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 7.76e-250 778.0
REGS1_k127_2016011_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 446.0
REGS1_k127_2310640_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 7.744e-280 861.0
REGS1_k127_2310640_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 5.445e-272 840.0
REGS1_k127_2310640_10 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 327.0
REGS1_k127_2310640_11 Helix-turn-helix domain K15539 - - 0.000000000000000000000000000000000000000000000000000006819 202.0
REGS1_k127_2310640_12 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000000004175 149.0
REGS1_k127_2310640_13 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000000000001767 95.0
REGS1_k127_2310640_14 - - - - 0.00000000000000000006341 98.0
REGS1_k127_2310640_16 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000008834 50.0
REGS1_k127_2310640_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.194e-255 791.0
REGS1_k127_2310640_3 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 3.343e-253 784.0
REGS1_k127_2310640_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 8.981e-238 739.0
REGS1_k127_2310640_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 6.056e-211 659.0
REGS1_k127_2310640_6 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 610.0
REGS1_k127_2310640_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 603.0
REGS1_k127_2310640_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 567.0
REGS1_k127_2310640_9 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 471.0
REGS1_k127_2347787_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.588e-247 767.0
REGS1_k127_2347787_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 4.247e-245 760.0
REGS1_k127_2347787_2 EamA-like transporter family K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 458.0
REGS1_k127_2347787_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 391.0
REGS1_k127_2347787_4 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000001345 239.0
REGS1_k127_2347787_5 SpoIIAA-like - - - 0.00000000000000000000000000000000000000000000000000000002701 211.0
REGS1_k127_2347787_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000000009739 157.0
REGS1_k127_2347787_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000003101 108.0
REGS1_k127_2347787_9 STAS domain K07122 - - 0.000001529 50.0
REGS1_k127_2423356_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1297.0
REGS1_k127_2423356_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1219.0
REGS1_k127_2423356_10 peptidase - - - 0.00000000000000000000000000000000000000000000000000000005711 206.0
REGS1_k127_2423356_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000000000006666 169.0
REGS1_k127_2423356_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000001255 139.0
REGS1_k127_2423356_13 - - - - 0.000000000000007432 77.0
REGS1_k127_2423356_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1085.0
REGS1_k127_2423356_3 ABC transporter transmembrane region K06147,K11004 - - 9.737e-304 948.0
REGS1_k127_2423356_4 Participates in both transcription termination and antitermination K02600 - - 2.779e-291 897.0
REGS1_k127_2423356_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 572.0
REGS1_k127_2423356_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 516.0
REGS1_k127_2423356_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 306.0
REGS1_k127_2423356_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001884 251.0
REGS1_k127_2423356_9 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008548 247.0
REGS1_k127_2424810_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 438.0
REGS1_k127_2424810_1 Histidine kinase K10125 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 445.0
REGS1_k127_2424810_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 387.0
REGS1_k127_2424810_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 336.0
REGS1_k127_2445777_0 Receptor family ligand binding region K01999 - - 5.483e-219 683.0
REGS1_k127_2445777_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 437.0
REGS1_k127_2445777_2 VirC1 protein K03496 - - 0.000000000000000000000000000000000000000000000000000000000005076 208.0
REGS1_k127_2445777_3 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000000000000000009609 159.0
REGS1_k127_2445777_4 Cytochrome K08738 - - 0.0000000000000000007883 94.0
REGS1_k127_2505206_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 1.153e-263 816.0
REGS1_k127_2505206_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 329.0
REGS1_k127_2546732_0 Diguanylate cyclase - - - 8.079e-259 829.0
REGS1_k127_2546732_1 Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 477.0
REGS1_k127_2570988_0 SMART von Willebrand factor type A - - - 0.0 1324.0
REGS1_k127_2570988_1 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 6.644e-212 659.0
REGS1_k127_2570988_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 562.0
REGS1_k127_2570988_3 ATPase associated with various cellular activities AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009797 503.0
REGS1_k127_2570988_4 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 375.0
REGS1_k127_2570988_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 287.0
REGS1_k127_2570988_6 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000003806 91.0
REGS1_k127_2615300_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 4.096e-321 994.0
REGS1_k127_2615300_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 597.0
REGS1_k127_2615300_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 512.0
REGS1_k127_2615300_3 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 466.0
REGS1_k127_2615300_4 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 324.0
REGS1_k127_2615300_5 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.000000000000000000000000000000000000000000000000003106 181.0
REGS1_k127_2653077_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 557.0
REGS1_k127_2653077_1 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 331.0
REGS1_k127_2653077_10 Transcriptional regulator - - - 0.0000000000000000000000000434 109.0
REGS1_k127_2653077_11 - - - - 0.00000000000000000003183 93.0
REGS1_k127_2653077_12 - - - - 0.0000000000000001152 85.0
REGS1_k127_2653077_13 - - - - 0.00000000001654 68.0
REGS1_k127_2653077_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 294.0
REGS1_k127_2653077_3 PFAM Signal transduction response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002015 248.0
REGS1_k127_2653077_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000004117 212.0
REGS1_k127_2653077_5 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000000000000000000001982 162.0
REGS1_k127_2653077_6 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000000000001576 144.0
REGS1_k127_2653077_7 3'-5' exonuclease - - - 0.000000000000000000000000000000000008 141.0
REGS1_k127_2653077_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000002331 130.0
REGS1_k127_2653077_9 Planctomycete cytochrome C - - - 0.0000000000000000000000000006039 117.0
REGS1_k127_2656489_0 methyltransferase small - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 572.0
REGS1_k127_2656489_1 SMART adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 525.0
REGS1_k127_2656489_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 422.0
REGS1_k127_2656489_3 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003923 279.0
REGS1_k127_2656489_4 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000001413 242.0
REGS1_k127_2657693_0 MscS Mechanosensitive ion channel - - - 2.707e-250 781.0
REGS1_k127_2657693_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 2.01e-247 767.0
REGS1_k127_2657693_10 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000000000000000000000000000000000000000003298 205.0
REGS1_k127_2657693_12 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000001516 170.0
REGS1_k127_2657693_13 Chitinase class I K03791 - - 0.00000000000000000000000000000000000000000001581 180.0
REGS1_k127_2657693_14 - - - - 0.0000000000000000000000000000000000001299 154.0
REGS1_k127_2657693_15 BRO family, N-terminal domain - - - 0.0000000000000000000000000000000000005624 140.0
REGS1_k127_2657693_16 General secretion pathway K02462 - - 0.000000000000000000000000000000002291 136.0
REGS1_k127_2657693_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 2.294e-198 626.0
REGS1_k127_2657693_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 596.0
REGS1_k127_2657693_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 565.0
REGS1_k127_2657693_5 general secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 362.0
REGS1_k127_2657693_6 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 360.0
REGS1_k127_2657693_7 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 328.0
REGS1_k127_2657693_8 PFAM Tripartite ATP-independent periplasmic transporter DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 310.0
REGS1_k127_2657693_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001019 264.0
REGS1_k127_26713_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1582.0
REGS1_k127_26713_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 577.0
REGS1_k127_26713_2 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 434.0
REGS1_k127_26713_3 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000253 148.0
REGS1_k127_26713_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000002051 117.0
REGS1_k127_26713_5 - - - - 0.000000000004356 68.0
REGS1_k127_26713_6 Cyclic nucleotide-monophosphate binding domain - - - 0.00000003873 55.0
REGS1_k127_2692152_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1060.0
REGS1_k127_2692152_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000001992 219.0
REGS1_k127_2692152_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000001118 124.0
REGS1_k127_2692152_3 - - - - 0.000000000000000000004336 97.0
REGS1_k127_2709999_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.357e-266 825.0
REGS1_k127_2709999_1 Histidine kinase - - - 3.258e-220 709.0
REGS1_k127_2709999_10 Protein of unknown function (DUF1653) - - - 0.00000000000000000000000000000008604 124.0
REGS1_k127_2709999_11 Alpha beta hydrolase superfamily K01563 - 3.8.1.5 0.00000000001945 70.0
REGS1_k127_2709999_2 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 385.0
REGS1_k127_2709999_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 368.0
REGS1_k127_2709999_4 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 325.0
REGS1_k127_2709999_5 protein-glutamate methylesterase activity K03412,K03413,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 310.0
REGS1_k127_2709999_6 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002229 281.0
REGS1_k127_2709999_7 Protein of unknown function (DUF3301) - - - 0.00000000000000000000000000000000000000000000000000937 183.0
REGS1_k127_2709999_8 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000003926 158.0
REGS1_k127_2709999_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000001706 148.0
REGS1_k127_2711672_0 AAA domain - - - 0.0 1305.0
REGS1_k127_2711672_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 594.0
REGS1_k127_2711672_2 ABC transporter K06020 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 332.0
REGS1_k127_2711672_3 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 318.0
REGS1_k127_2711672_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000007892 184.0
REGS1_k127_2711672_6 - - - - 0.0000000000000004465 81.0
REGS1_k127_2755902_0 Domain of unknown function (DUF3400) - - - 5.04e-280 866.0
REGS1_k127_2755902_1 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 376.0
REGS1_k127_2755902_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 342.0
REGS1_k127_2755902_3 Hemolysin-type calcium-binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 343.0
REGS1_k127_2755902_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000000000000000000003165 249.0
REGS1_k127_2755902_5 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000008776 231.0
REGS1_k127_276843_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 589.0
REGS1_k127_276843_1 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 527.0
REGS1_k127_276843_2 permeases of the drug metabolite transporter (Dmt) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 494.0
REGS1_k127_276843_3 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 445.0
REGS1_k127_276843_4 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 377.0
REGS1_k127_276843_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001423 269.0
REGS1_k127_276843_6 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000003229 186.0
REGS1_k127_276843_7 PFAM HopJ type III effector protein - - - 0.0000000000000000000000000000000000000000000000004261 177.0
REGS1_k127_276843_8 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000001366 164.0
REGS1_k127_2792818_0 Pyridine nucleotide-disulphide oxidoreductase K00529,K18227,K18249 - 1.18.1.3 1.102e-205 644.0
REGS1_k127_2792818_1 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 541.0
REGS1_k127_2792818_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 351.0
REGS1_k127_2792818_3 membrane K08994 - - 0.00000000000000000000000000001303 117.0
REGS1_k127_2817389_0 Two component signalling adaptor domain - - - 5.409e-305 954.0
REGS1_k127_2817389_1 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 503.0
REGS1_k127_2817389_10 - - - - 0.00000006044 61.0
REGS1_k127_2817389_2 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 304.0
REGS1_k127_2817389_3 PFAM Helix-turn-helix, type 11 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
REGS1_k127_2817389_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000002124 219.0
REGS1_k127_2817389_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000004329 134.0
REGS1_k127_2817389_6 TfoX C-terminal domain K07343 - - 0.000000000000000000000000001419 113.0
REGS1_k127_2817389_8 Domain of unknown function (DU1801) - - - 0.0000000000000000000008028 96.0
REGS1_k127_2817389_9 - - - - 0.0000000000001511 74.0
REGS1_k127_2839815_0 Large family of predicted nucleotide-binding domains K07175 - - 5.494e-286 882.0
REGS1_k127_2839815_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 359.0
REGS1_k127_2839815_2 Intracellular septation protein A K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 297.0
REGS1_k127_2839815_3 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001774 279.0
REGS1_k127_2839815_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000564 271.0
REGS1_k127_2839815_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005767 265.0
REGS1_k127_2839815_6 Belongs to the MsrB Met sulfoxide reductase family K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 254.0
REGS1_k127_2839815_7 YCII-related domain K09780 - - 0.000000000000000000000000000000000000000000003291 167.0
REGS1_k127_2839815_8 Acetyltransferase (GNAT) domain - - - 0.000000000002437 67.0
REGS1_k127_2930248_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1634.0
REGS1_k127_2930248_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 7.841e-213 682.0
REGS1_k127_2930248_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000005646 146.0
REGS1_k127_2930248_11 Glyoxalase-like domain - - - 0.00000000000000000000007398 104.0
REGS1_k127_2930248_2 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 600.0
REGS1_k127_2930248_3 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 409.0
REGS1_k127_2930248_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 376.0
REGS1_k127_2930248_5 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 336.0
REGS1_k127_2930248_6 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
REGS1_k127_2930248_7 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003282 259.0
REGS1_k127_2930248_8 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003858 238.0
REGS1_k127_2930248_9 - - - - 0.00000000000000000000000000000000000000000000000000000008228 205.0
REGS1_k127_2942156_0 Part of a membrane complex involved in electron transport K03615 - - 3.464e-274 851.0
REGS1_k127_2942156_1 Part of a membrane complex involved in electron transport K03614 - - 2.124e-200 627.0
REGS1_k127_2942156_2 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 359.0
REGS1_k127_2942156_3 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 364.0
REGS1_k127_2942156_4 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 340.0
REGS1_k127_2942156_5 K+ potassium transporter K03549 - - 0.00000000000000000000000000000000000000000000000000000000000000001388 224.0
REGS1_k127_2942156_6 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000002731 132.0
REGS1_k127_2955011_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1607.0
REGS1_k127_2955011_1 PFAM sodium calcium exchanger membrane region K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 612.0
REGS1_k127_2955011_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001439 238.0
REGS1_k127_2955011_11 Protein of unknown function (DUF1175) K09934 - - 0.00000000000000000000000000000000000000000000000000000001348 204.0
REGS1_k127_2955011_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 519.0
REGS1_k127_2955011_3 Stage II sporulation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 457.0
REGS1_k127_2955011_4 Uncharacterized protein conserved in bacteria (DUF2138) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 406.0
REGS1_k127_2955011_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 325.0
REGS1_k127_2955011_6 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 320.0
REGS1_k127_2955011_7 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 314.0
REGS1_k127_2955011_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005137 269.0
REGS1_k127_2955011_9 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
REGS1_k127_3020697_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1753.0
REGS1_k127_3020697_1 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000587 224.0
REGS1_k127_3020697_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000002162 124.0
REGS1_k127_3084995_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 413.0
REGS1_k127_3084995_1 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 318.0
REGS1_k127_3084995_2 - - - - 0.00000000000000000000000000000000000002299 145.0
REGS1_k127_3084995_3 Methyl-transferase - - - 0.0002039 47.0
REGS1_k127_311973_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.043e-253 785.0
REGS1_k127_311973_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 471.0
REGS1_k127_311973_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 402.0
REGS1_k127_311973_3 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 315.0
REGS1_k127_311973_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000003427 171.0
REGS1_k127_311973_5 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000000000004898 117.0
REGS1_k127_3128268_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 575.0
REGS1_k127_3128268_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 373.0
REGS1_k127_3128268_2 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 364.0
REGS1_k127_3128268_3 PFAM CHASE2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 300.0
REGS1_k127_3128268_4 crp fnr family - - - 0.0000000000000000000000000000000000000000000000002923 182.0
REGS1_k127_3128268_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000005451 111.0
REGS1_k127_3132871_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 3.28e-245 765.0
REGS1_k127_3132871_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 5.462e-201 634.0
REGS1_k127_3132871_10 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001627 272.0
REGS1_k127_3132871_11 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000000000000000000000000005933 224.0
REGS1_k127_3132871_12 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000000000000000001424 192.0
REGS1_k127_3132871_13 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000005849 178.0
REGS1_k127_3132871_14 - - - - 0.0000000000000000000000000000000002274 141.0
REGS1_k127_3132871_16 NusG domain II - - - 0.0000000000000000002597 93.0
REGS1_k127_3132871_2 endonuclease III K03575 - - 7.514e-196 613.0
REGS1_k127_3132871_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 525.0
REGS1_k127_3132871_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 496.0
REGS1_k127_3132871_5 P-loop ATPase protein family K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 442.0
REGS1_k127_3132871_6 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 436.0
REGS1_k127_3132871_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 384.0
REGS1_k127_3132871_8 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 319.0
REGS1_k127_3132871_9 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 295.0
REGS1_k127_3226174_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0 1065.0
REGS1_k127_3226174_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 499.0
REGS1_k127_322728_0 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 1.277e-265 822.0
REGS1_k127_322728_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 458.0
REGS1_k127_322728_2 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 419.0
REGS1_k127_322728_3 Transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 414.0
REGS1_k127_322728_4 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000118 221.0
REGS1_k127_322728_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000005248 136.0
REGS1_k127_322728_6 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000000000000000000004437 115.0
REGS1_k127_322728_7 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.0000000007051 59.0
REGS1_k127_3426334_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 2.056e-280 868.0
REGS1_k127_3454309_0 Neisseria PilC beta-propeller domain K02674 - - 0.0 1482.0
REGS1_k127_3454309_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 544.0
REGS1_k127_3454309_2 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 304.0
REGS1_k127_3454309_3 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001111 282.0
REGS1_k127_3454309_4 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001273 248.0
REGS1_k127_3454309_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000007432 208.0
REGS1_k127_3454309_6 Type II transport protein GspH K08084 - - 0.000000000000000000000000000000000000000000000000006192 188.0
REGS1_k127_3454309_7 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000000000000000000000007453 172.0
REGS1_k127_3454309_8 type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000000000000002426 143.0
REGS1_k127_3454309_9 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000003132 78.0
REGS1_k127_347724_0 fad dependent oxidoreductase K07137 - - 2.023e-308 949.0
REGS1_k127_347724_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 7.302e-276 850.0
REGS1_k127_347724_10 - - - - 0.0000000000000000000000001234 110.0
REGS1_k127_347724_2 SMART ATP-binding region ATPase domain protein - - - 3.849e-230 751.0
REGS1_k127_347724_3 metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 559.0
REGS1_k127_347724_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 331.0
REGS1_k127_347724_5 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 332.0
REGS1_k127_347724_6 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 318.0
REGS1_k127_347724_7 response regulator K02485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006995 276.0
REGS1_k127_347724_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005973 259.0
REGS1_k127_3504806_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.185e-276 852.0
REGS1_k127_3504806_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 4.374e-256 797.0
REGS1_k127_3504806_10 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007906 274.0
REGS1_k127_3504806_11 Protein of unknown function (DUF560) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005563 277.0
REGS1_k127_3504806_12 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 259.0
REGS1_k127_3504806_13 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000001213 223.0
REGS1_k127_3504806_14 PFAM FecR protein - - - 0.0000000000000000000000000219 128.0
REGS1_k127_3504806_15 F plasmid transfer operon, TraF, protein - - - 0.0000000000000000000000003601 119.0
REGS1_k127_3504806_2 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 2.487e-217 677.0
REGS1_k127_3504806_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 439.0
REGS1_k127_3504806_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 426.0
REGS1_k127_3504806_5 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 426.0
REGS1_k127_3504806_6 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 392.0
REGS1_k127_3504806_7 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 384.0
REGS1_k127_3504806_8 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 372.0
REGS1_k127_3504806_9 Bacterial dnaA protein K10763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 331.0
REGS1_k127_3517473_0 PFAM major facilitator superfamily MFS_1 K08218 - - 2.218e-228 711.0
REGS1_k127_3517473_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.966e-226 704.0
REGS1_k127_3517473_10 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.000000000000000000000001104 106.0
REGS1_k127_3517473_12 Protein of unknown function (DUF433) - - - 0.0000000000000000001745 91.0
REGS1_k127_3517473_13 Protein of unknown function (DUF455) - - - 0.00000000000008934 74.0
REGS1_k127_3517473_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 396.0
REGS1_k127_3517473_3 TIGRFAM methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 356.0
REGS1_k127_3517473_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 331.0
REGS1_k127_3517473_5 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 320.0
REGS1_k127_3517473_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000000000000000000000000000000001974 205.0
REGS1_k127_3517473_7 transporter component K07112 - - 0.000000000000000000000000000000000000000000000002528 177.0
REGS1_k127_3517473_8 transporter component - - - 0.000000000000000000000000000000000000000000003174 171.0
REGS1_k127_3517473_9 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000001482 162.0
REGS1_k127_352532_0 Peptidase family M48 - - - 1.396e-213 672.0
REGS1_k127_352532_1 serine threonine protein kinase K12132 - 2.7.11.1 2.231e-209 658.0
REGS1_k127_352532_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000002608 194.0
REGS1_k127_352532_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000004812 171.0
REGS1_k127_352532_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000001669 115.0
REGS1_k127_352532_6 membrane - - - 0.0000000191 60.0
REGS1_k127_3534584_0 S-adenosyl-L-methionine-dependent methyltransferase K15461 - 2.1.1.61 4.952e-268 837.0
REGS1_k127_3534584_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 503.0
REGS1_k127_3534584_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 440.0
REGS1_k127_3534584_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 439.0
REGS1_k127_3534584_4 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 311.0
REGS1_k127_3534584_5 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000004239 218.0
REGS1_k127_3534584_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000286 211.0
REGS1_k127_3534584_7 - - - - 0.0000000000000001126 83.0
REGS1_k127_3535747_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 2.16e-318 987.0
REGS1_k127_3535747_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 562.0
REGS1_k127_3535747_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 437.0
REGS1_k127_3535747_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 421.0
REGS1_k127_3535747_4 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 292.0
REGS1_k127_3541216_0 RNB K01147 - 3.1.13.1 0.0 1086.0
REGS1_k127_3541216_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 586.0
REGS1_k127_3541216_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 455.0
REGS1_k127_3541216_3 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 379.0
REGS1_k127_3541216_4 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 356.0
REGS1_k127_3541216_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 317.0
REGS1_k127_3541216_6 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002343 247.0
REGS1_k127_3541216_7 SMART Calcium-binding EF-hand-containing protein - - - 0.0000000000000000000000000000000000000000000000000003059 190.0
REGS1_k127_3541216_8 Cytochrome C oxidase, cbb3-type, subunit III K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000008755 113.0
REGS1_k127_3541216_9 - - - - 0.00000000004396 68.0
REGS1_k127_3544999_0 HELICc2 K03722 - 3.6.4.12 0.0 1048.0
REGS1_k127_3544999_1 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 483.0
REGS1_k127_3544999_2 major facilitator superfamily K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 352.0
REGS1_k127_3544999_3 Transcription regulator that can specifically activate or repress expression of target genes K06075 - - 0.000000000000000000000000000000000000000000000000000000000004901 210.0
REGS1_k127_3566983_0 Histidine Phosphotransfer domain - - - 5.129e-217 727.0
REGS1_k127_3566983_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 526.0
REGS1_k127_3566983_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 494.0
REGS1_k127_3566983_3 transport system periplasmic component K01989 - - 0.0000000000000000000000000000000000000000000000000001569 193.0
REGS1_k127_3581570_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1142.0
REGS1_k127_3581570_1 PFAM glycine cleavage T protein (aminomethyl transferase) K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 428.0
REGS1_k127_3581570_2 Cobalt uptake substrate-specific transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 323.0
REGS1_k127_3581570_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000006624 152.0
REGS1_k127_3581570_6 - - - - 0.000000000000000000004035 93.0
REGS1_k127_3602575_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 4.914e-196 616.0
REGS1_k127_3602575_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 506.0
REGS1_k127_3602575_2 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 336.0
REGS1_k127_3602575_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000004642 201.0
REGS1_k127_3602575_4 Trm112p-like protein K09791 - - 0.0000000000000000000000006156 107.0
REGS1_k127_3602575_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000001166 100.0
REGS1_k127_3632229_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1823.0
REGS1_k127_3632229_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002989 232.0
REGS1_k127_3632229_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000003703 122.0
REGS1_k127_3632229_3 Putative addiction module component - - - 0.00000000000000002177 85.0
REGS1_k127_3635575_0 MMPL family - - - 0.0 1071.0
REGS1_k127_3635575_1 Sodium/hydrogen exchanger family - - - 1.876e-234 729.0
REGS1_k127_3635575_2 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 477.0
REGS1_k127_3635575_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000791 271.0
REGS1_k127_3635575_4 FabA-like domain - - - 0.0000000000000000004122 87.0
REGS1_k127_3690015_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1166.0
REGS1_k127_3690015_1 SMART PDZ DHR GLGF domain protein K11749 - - 1.498e-233 728.0
REGS1_k127_3690015_10 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 294.0
REGS1_k127_3690015_11 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003408 274.0
REGS1_k127_3690015_12 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000000000000000000000000000000000000000000000000000004847 227.0
REGS1_k127_3690015_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000404 223.0
REGS1_k127_3690015_14 Copper resistance protein D - - - 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
REGS1_k127_3690015_15 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000003483 183.0
REGS1_k127_3690015_16 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000000000000000000001327 159.0
REGS1_k127_3690015_18 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.00000000000001639 74.0
REGS1_k127_3690015_19 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000657 63.0
REGS1_k127_3690015_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 1.373e-214 672.0
REGS1_k127_3690015_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 1.394e-207 649.0
REGS1_k127_3690015_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 583.0
REGS1_k127_3690015_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 495.0
REGS1_k127_3690015_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 489.0
REGS1_k127_3690015_7 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 490.0
REGS1_k127_3690015_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 325.0
REGS1_k127_3690015_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 297.0
REGS1_k127_3695811_0 pilus assembly protein FimV K08086 - - 1.64e-242 779.0
REGS1_k127_3695811_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 5.529e-224 696.0
REGS1_k127_3695811_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 461.0
REGS1_k127_3695811_3 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 340.0
REGS1_k127_3695811_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 319.0
REGS1_k127_3695811_5 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006756 275.0
REGS1_k127_3695811_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000009999 151.0
REGS1_k127_3708131_0 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 432.0
REGS1_k127_3708131_1 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 304.0
REGS1_k127_3708131_2 Peptidase m48 ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000001784 222.0
REGS1_k127_3708131_3 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000002392 135.0
REGS1_k127_3708131_4 Sh3 type 3 domain protein K02450,K12132 - 2.7.11.1 0.00000000000000009053 87.0
REGS1_k127_3724729_0 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 330.0
REGS1_k127_3724729_1 PFAM Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000696 273.0
REGS1_k127_3724729_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006951 267.0
REGS1_k127_3724729_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003697 248.0
REGS1_k127_3724729_4 - - - - 0.0000000000000000000000000000000000000000000000000000002329 201.0
REGS1_k127_3724729_5 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000000000000005296 190.0
REGS1_k127_3761087_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.913e-227 706.0
REGS1_k127_3761087_1 Major Facilitator Superfamily - - - 1.485e-223 697.0
REGS1_k127_3761087_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 361.0
REGS1_k127_3761087_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 351.0
REGS1_k127_3761087_4 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000001237 205.0
REGS1_k127_3761087_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000001598 206.0
REGS1_k127_3761087_6 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000001349 109.0
REGS1_k127_3790849_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 9.874e-311 968.0
REGS1_k127_3790849_1 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 1.076e-283 877.0
REGS1_k127_3790849_10 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 371.0
REGS1_k127_3790849_11 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 366.0
REGS1_k127_3790849_12 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 297.0
REGS1_k127_3790849_13 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004081 277.0
REGS1_k127_3790849_14 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000006276 217.0
REGS1_k127_3790849_15 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000000000001611 212.0
REGS1_k127_3790849_16 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000000007371 190.0
REGS1_k127_3790849_17 PFAM cytochrome c class I K08738 - - 0.000000000000000000000000000000000000002906 151.0
REGS1_k127_3790849_18 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000000000000001056 140.0
REGS1_k127_3790849_19 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000001185 138.0
REGS1_k127_3790849_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 9.821e-272 839.0
REGS1_k127_3790849_20 Domain of unknown function (DUF4149) - - - 0.0000000000000000000000000000000006374 133.0
REGS1_k127_3790849_21 Protein of unknown function (DUF2971) - - - 0.000000000000000000000000000007023 130.0
REGS1_k127_3790849_22 COG1403 Restriction endonuclease K07451 - - 0.000000000000000000000284 102.0
REGS1_k127_3790849_3 Sugar (and other) transporter - - - 2.877e-226 706.0
REGS1_k127_3790849_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 604.0
REGS1_k127_3790849_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 532.0
REGS1_k127_3790849_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 515.0
REGS1_k127_3790849_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 488.0
REGS1_k127_3790849_8 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 398.0
REGS1_k127_3790849_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 393.0
REGS1_k127_3806429_0 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 601.0
REGS1_k127_3806429_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 434.0
REGS1_k127_3806429_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 301.0
REGS1_k127_3842706_0 Domain of unknown function DUF21 - - - 3.794e-199 628.0
REGS1_k127_3842706_1 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 540.0
REGS1_k127_3842706_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 505.0
REGS1_k127_3842706_3 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 344.0
REGS1_k127_3887900_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 513.0
REGS1_k127_3887900_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000001047 228.0
REGS1_k127_3887900_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000005432 182.0
REGS1_k127_3899909_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0 1023.0
REGS1_k127_3899909_1 DSBA-like thioredoxin domain K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 317.0
REGS1_k127_3899909_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 280.0
REGS1_k127_3899909_3 Sporulation related domain - - - 0.0000000000000000000000000000000000000000001088 167.0
REGS1_k127_3915834_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1589.0
REGS1_k127_3915834_1 Tetratricopeptide repeats - - - 9.635e-220 697.0
REGS1_k127_3915834_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 568.0
REGS1_k127_3915834_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 501.0
REGS1_k127_3915834_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 394.0
REGS1_k127_3915834_5 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000000000000000000000000000000000000000001631 222.0
REGS1_k127_3915834_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000003552 153.0
REGS1_k127_3915834_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000007599 68.0
REGS1_k127_3919331_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1358.0
REGS1_k127_3919331_1 Glycosyl hydrolase family 57 - - - 7.078e-306 946.0
REGS1_k127_3919331_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.483e-254 788.0
REGS1_k127_3919331_3 Starch synthase catalytic domain K00703 - 2.4.1.21 2.597e-239 747.0
REGS1_k127_3919331_4 Belongs to the GPI family K01810 - 5.3.1.9 1.046e-228 720.0
REGS1_k127_3919331_5 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 558.0
REGS1_k127_3919331_6 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001814 251.0
REGS1_k127_3919331_7 Addiction module toxin, RelE StbE - - - 0.000000000000003925 78.0
REGS1_k127_3919331_8 - - - - 0.000000004107 57.0
REGS1_k127_4002527_0 PFAM plasmid stabilization system - - - 0.0000000000000000000000000000000000000000000000000000000005029 202.0
REGS1_k127_4002527_1 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000004278 135.0
REGS1_k127_4002527_2 Activator of Hsp90 ATPase 1 family protein - - - 0.00000000000000000000000001124 109.0
REGS1_k127_4050499_0 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 531.0
REGS1_k127_4050499_1 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 333.0
REGS1_k127_4050499_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004927 265.0
REGS1_k127_4050499_3 Chitinase class I K03791 - - 0.0002404 51.0
REGS1_k127_4110944_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 2101.0
REGS1_k127_4110944_1 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.0 1076.0
REGS1_k127_4110944_2 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 506.0
REGS1_k127_4110944_3 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 354.0
REGS1_k127_4110944_4 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 0.00000000000000000000000000000000000003735 149.0
REGS1_k127_4110944_5 PFAM NAD-dependent epimerase dehydratase K00091,K01784 - 1.1.1.219,5.1.3.2 0.00000000000000000000000001255 110.0
REGS1_k127_421343_0 HMGL-like K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 556.0
REGS1_k127_421343_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 449.0
REGS1_k127_421343_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 282.0
REGS1_k127_421343_3 NifZ domain K02597 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002518 278.0
REGS1_k127_421343_4 Nitrogen fixation protein NifW K02595 - - 0.00000000000000000000000000000000000000000000000000001872 189.0
REGS1_k127_4282785_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.468e-292 906.0
REGS1_k127_4282785_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 1.313e-271 841.0
REGS1_k127_4282785_10 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 503.0
REGS1_k127_4282785_11 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 440.0
REGS1_k127_4282785_12 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 427.0
REGS1_k127_4282785_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 295.0
REGS1_k127_4282785_14 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001571 278.0
REGS1_k127_4282785_15 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000001378 185.0
REGS1_k127_4282785_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000000000000008356 133.0
REGS1_k127_4282785_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.115e-259 808.0
REGS1_k127_4282785_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 4.841e-243 756.0
REGS1_k127_4282785_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.864e-221 691.0
REGS1_k127_4282785_5 Predicted membrane protein (DUF2339) - - - 5.639e-200 654.0
REGS1_k127_4282785_6 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 567.0
REGS1_k127_4282785_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 547.0
REGS1_k127_4282785_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 533.0
REGS1_k127_4282785_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 537.0
REGS1_k127_4519404_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1386.0
REGS1_k127_4519404_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1221.0
REGS1_k127_4519404_2 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004601 282.0
REGS1_k127_4519404_3 - - - - 0.000000000000000000000000000000000000000000000000000009919 196.0
REGS1_k127_4519404_4 Domain of unknown function (DUF4124) K08309 - - 0.0000000000000000000000000000000000000000000001086 175.0
REGS1_k127_4519404_5 - - - - 0.0000000000000000000000000000000000002474 147.0
REGS1_k127_4519404_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000000009372 143.0
REGS1_k127_4519404_7 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000000001123 128.0
REGS1_k127_4519404_8 domain protein - - - 0.0000000000000000000000000000002812 135.0
REGS1_k127_4581857_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 9.55e-284 874.0
REGS1_k127_4581857_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 411.0
REGS1_k127_4581857_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000002795 179.0
REGS1_k127_4581857_3 - - - - 0.0000000000000000000001508 104.0
REGS1_k127_4581857_4 - - - - 0.0000000000000005283 78.0
REGS1_k127_4581857_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000001106 61.0
REGS1_k127_4581857_6 Transposase, Mutator family - - - 0.00000002101 55.0
REGS1_k127_4631529_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 493.0
REGS1_k127_4631529_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 452.0
REGS1_k127_4631529_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 312.0
REGS1_k127_4631529_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000000006165 221.0
REGS1_k127_4631529_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000000000002597 165.0
REGS1_k127_4631529_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000001553 57.0
REGS1_k127_4632352_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 2.298e-259 806.0
REGS1_k127_4632352_1 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000001362 200.0
REGS1_k127_4637079_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 307.0
REGS1_k127_4637079_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004429 253.0
REGS1_k127_4637079_2 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000001427 196.0
REGS1_k127_4637079_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000009223 151.0
REGS1_k127_4640299_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1130.0
REGS1_k127_4640299_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.395e-289 892.0
REGS1_k127_4640299_2 Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000002247 231.0
REGS1_k127_4646482_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1061.0
REGS1_k127_4646482_1 aminoacyl-histidine dipeptidase K01270 - - 1.091e-229 719.0
REGS1_k127_4646482_10 DnaJ-class molecular chaperone with C-terminal Zn finger domain K05516 - - 0.00000000000001335 84.0
REGS1_k127_4646482_11 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000001036 51.0
REGS1_k127_4646482_2 PFAM nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 337.0
REGS1_k127_4646482_3 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 338.0
REGS1_k127_4646482_4 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002854 244.0
REGS1_k127_4646482_5 - - - - 0.00000000000000000000000000000000000000000001975 164.0
REGS1_k127_4646482_6 Protein of unknown function (DUF3617) - - - 0.000000000000000000000001354 108.0
REGS1_k127_4646482_8 heat shock protein binding K05516 - - 0.00000000000000000327 95.0
REGS1_k127_4664447_0 - - - - 2.095e-254 791.0
REGS1_k127_4664447_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 572.0
REGS1_k127_4664447_2 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 338.0
REGS1_k127_4664447_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000001422 186.0
REGS1_k127_4664447_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000002011 176.0
REGS1_k127_4664447_5 COG0666 FOG Ankyrin repeat K06867 - - 0.000000000000000000000000000000000000000000144 183.0
REGS1_k127_4664447_6 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000000001948 139.0
REGS1_k127_4664447_7 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000007655 110.0
REGS1_k127_4664845_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1001.0
REGS1_k127_4664845_1 PFAM Thiamine pyrophosphate K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 605.0
REGS1_k127_4664845_2 GfdT protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 576.0
REGS1_k127_4664845_3 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 257.0
REGS1_k127_4664845_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000001436 160.0
REGS1_k127_4664845_5 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000001221 129.0
REGS1_k127_4664845_6 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K03737 - 1.2.7.1 0.0000000000000000161 81.0
REGS1_k127_4677767_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1641.0
REGS1_k127_4692706_0 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 609.0
REGS1_k127_4692706_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 360.0
REGS1_k127_4692706_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 312.0
REGS1_k127_4692706_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000003567 153.0
REGS1_k127_4692706_4 - - - - 0.0000000006779 64.0
REGS1_k127_4713343_0 Putative diguanylate phosphodiesterase - - - 0.0 1036.0
REGS1_k127_4713343_1 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 496.0
REGS1_k127_4713343_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 413.0
REGS1_k127_4713343_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000008442 98.0
REGS1_k127_4713838_0 ABC transporter transmembrane region K06147 - - 0.0 1030.0
REGS1_k127_4713838_1 TPR repeat - - - 7.993e-258 805.0
REGS1_k127_4713838_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 467.0
REGS1_k127_4713838_3 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 405.0
REGS1_k127_4713838_4 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 391.0
REGS1_k127_4713838_5 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 362.0
REGS1_k127_4713838_6 Prokaryotic N-terminal methylation motif K02650 - - 0.0001663 48.0
REGS1_k127_4737105_0 Mur ligase family, catalytic domain K01924 - 6.3.2.8 4.886e-263 815.0
REGS1_k127_4737105_1 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 537.0
REGS1_k127_4737105_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 495.0
REGS1_k127_4737105_3 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 484.0
REGS1_k127_4737105_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 346.0
REGS1_k127_4737105_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000005367 48.0
REGS1_k127_4746253_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.319e-296 914.0
REGS1_k127_4746253_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 574.0
REGS1_k127_4746253_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 473.0
REGS1_k127_4746253_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000001564 164.0
REGS1_k127_4746253_4 domain protein K20276 - - 0.000000000000000000000002426 117.0
REGS1_k127_4746253_5 Peptidase family M23 - - - 0.00000000000000001078 89.0
REGS1_k127_4747464_0 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 546.0
REGS1_k127_4747464_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 391.0
REGS1_k127_4747464_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 375.0
REGS1_k127_4747464_3 Protein of unknown function, DUF255 K06888 - - 0.00000007531 53.0
REGS1_k127_4757977_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.053e-306 942.0
REGS1_k127_4757977_1 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 435.0
REGS1_k127_4757977_2 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 349.0
REGS1_k127_4757977_3 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 316.0
REGS1_k127_4757977_4 - - - - 0.000000000000000000000000000000000001625 144.0
REGS1_k127_4757977_5 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000002257 102.0
REGS1_k127_4779993_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 8.419e-217 676.0
REGS1_k127_4779993_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 590.0
REGS1_k127_4779993_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000000003315 120.0
REGS1_k127_4779993_11 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000002098 97.0
REGS1_k127_4779993_2 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 486.0
REGS1_k127_4779993_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 471.0
REGS1_k127_4779993_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 387.0
REGS1_k127_4779993_5 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 372.0
REGS1_k127_4779993_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000004371 243.0
REGS1_k127_4779993_7 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000000000000001126 215.0
REGS1_k127_4779993_8 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000000000002604 185.0
REGS1_k127_4779993_9 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000001049 176.0
REGS1_k127_4805406_0 response regulator receiver - - - 8.762e-236 769.0
REGS1_k127_4805406_1 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 6.174e-228 726.0
REGS1_k127_4805406_10 PFAM Signal transduction response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000184 283.0
REGS1_k127_4805406_11 Putative thioesterase (yiiD_Cterm) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003022 265.0
REGS1_k127_4805406_12 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002609 237.0
REGS1_k127_4805406_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000261 230.0
REGS1_k127_4805406_14 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000002697 226.0
REGS1_k127_4805406_15 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000000000000001168 209.0
REGS1_k127_4805406_16 Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000003458 198.0
REGS1_k127_4805406_17 small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000001026 197.0
REGS1_k127_4805406_18 Response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000001147 190.0
REGS1_k127_4805406_19 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000006062 159.0
REGS1_k127_4805406_2 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 3.663e-209 657.0
REGS1_k127_4805406_20 CheW-like domain - - - 0.0000000000000000000000000000000000002222 150.0
REGS1_k127_4805406_21 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000000004053 118.0
REGS1_k127_4805406_22 - - - - 0.00000000000000000000000004482 113.0
REGS1_k127_4805406_23 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000001531 107.0
REGS1_k127_4805406_25 - - - - 0.0000000001268 70.0
REGS1_k127_4805406_26 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000001528 55.0
REGS1_k127_4805406_3 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 487.0
REGS1_k127_4805406_4 chemotaxis, protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 457.0
REGS1_k127_4805406_5 histidine kinase dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 404.0
REGS1_k127_4805406_6 Inner membrane protein CreD K06143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 350.0
REGS1_k127_4805406_7 Bacterial-like globin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 355.0
REGS1_k127_4805406_8 PFAM Response regulator receiver domain K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 337.0
REGS1_k127_4805406_9 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 343.0
REGS1_k127_4819410_0 Oxidoreductase FAD-binding domain protein K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 579.0
REGS1_k127_4819410_1 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 375.0
REGS1_k127_4850782_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 0.0 1001.0
REGS1_k127_4850782_1 Nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 6.467e-305 937.0
REGS1_k127_4850782_2 Pfam Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 387.0
REGS1_k127_4850782_3 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 366.0
REGS1_k127_4850782_4 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 355.0
REGS1_k127_4850782_5 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 273.0
REGS1_k127_4850782_6 - - - - 0.000000000000000000000000000000000000002283 148.0
REGS1_k127_4850782_7 nitrogen fixation K02593 - - 0.000000000000000000000000000000001703 131.0
REGS1_k127_4850782_8 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000000000000000001123 128.0
REGS1_k127_4850782_9 4Fe-4S binding domain - - - 0.00000000000000000000000000000008925 124.0
REGS1_k127_4877465_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 513.0
REGS1_k127_4877465_1 cyclic nucleotide binding K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006993 284.0
REGS1_k127_4877465_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000002116 143.0
REGS1_k127_4898899_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1347.0
REGS1_k127_4898899_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0 1157.0
REGS1_k127_4898899_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 572.0
REGS1_k127_4898899_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 556.0
REGS1_k127_4898899_12 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 441.0
REGS1_k127_4898899_13 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 401.0
REGS1_k127_4898899_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 393.0
REGS1_k127_4898899_15 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 385.0
REGS1_k127_4898899_16 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 391.0
REGS1_k127_4898899_17 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 383.0
REGS1_k127_4898899_18 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 370.0
REGS1_k127_4898899_19 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 363.0
REGS1_k127_4898899_2 PFAM DNA methylase N-4 N-6 K07316 - 2.1.1.72 1.308e-297 926.0
REGS1_k127_4898899_20 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 288.0
REGS1_k127_4898899_21 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001949 245.0
REGS1_k127_4898899_22 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004089 238.0
REGS1_k127_4898899_23 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000006544 213.0
REGS1_k127_4898899_24 TIGRFAM TonB family protein K03646 - - 0.0000000000000000000000000000000000000000000000000000000000389 214.0
REGS1_k127_4898899_25 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000005627 179.0
REGS1_k127_4898899_26 OmpA family K03640 - - 0.00000000000000000000000000000000000000000003696 167.0
REGS1_k127_4898899_3 PFAM Type III restriction enzyme, res subunit - - - 5.331e-295 930.0
REGS1_k127_4898899_4 heat shock protein binding - - - 1.908e-241 760.0
REGS1_k127_4898899_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 8.006e-237 752.0
REGS1_k127_4898899_6 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.537e-231 722.0
REGS1_k127_4898899_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.571e-214 671.0
REGS1_k127_4898899_8 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 2.975e-207 655.0
REGS1_k127_4898899_9 Involved in the TonB-independent uptake of proteins K03641 - - 3.645e-198 624.0
REGS1_k127_4906701_0 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0 1460.0
REGS1_k127_4906701_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1122.0
REGS1_k127_4906701_10 - - - - 0.00000000000000000000000004206 109.0
REGS1_k127_4906701_11 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000008588 111.0
REGS1_k127_4906701_2 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 1.739e-247 801.0
REGS1_k127_4906701_3 AAA domain K07028 - - 3.02e-215 685.0
REGS1_k127_4906701_4 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 391.0
REGS1_k127_4906701_5 Collagenase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 347.0
REGS1_k127_4906701_6 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 297.0
REGS1_k127_4906701_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004193 268.0
REGS1_k127_4906701_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000002799 216.0
REGS1_k127_4906701_9 SMART RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000000000000000000000000000000000003349 198.0
REGS1_k127_4951231_0 Ami_3 K01448 - 3.5.1.28 3.123e-206 648.0
REGS1_k127_4951231_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 7.237e-205 645.0
REGS1_k127_4951231_2 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 561.0
REGS1_k127_4951231_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 561.0
REGS1_k127_4951231_4 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 316.0
REGS1_k127_4951231_5 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000003116 209.0
REGS1_k127_4951231_6 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000007697 192.0
REGS1_k127_4951231_7 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000001604 162.0
REGS1_k127_4951231_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000008136 145.0
REGS1_k127_4951231_9 Competence protein K02237 - - 0.000000000000000000000000000000000000438 144.0
REGS1_k127_4968545_0 PAS domain containing protein - - - 0.0 1358.0
REGS1_k127_4968545_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 364.0
REGS1_k127_4968545_2 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 338.0
REGS1_k127_4968545_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 324.0
REGS1_k127_4968545_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001278 279.0
REGS1_k127_4968545_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002259 278.0
REGS1_k127_4968545_6 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000008051 232.0
REGS1_k127_4980283_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1035.0
REGS1_k127_4980283_1 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 533.0
REGS1_k127_4980283_2 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 489.0
REGS1_k127_4980283_3 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 459.0
REGS1_k127_4980283_4 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 331.0
REGS1_k127_4980283_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000006391 119.0
REGS1_k127_4990689_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 1.752e-222 691.0
REGS1_k127_4990689_1 glycosyl transferase group 1 K03208 - - 1.85e-217 680.0
REGS1_k127_4990689_2 Polysaccharide biosynthesis protein K17716 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 529.0
REGS1_k127_4990689_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 475.0
REGS1_k127_4990689_4 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 452.0
REGS1_k127_4990689_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 419.0
REGS1_k127_4990689_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 396.0
REGS1_k127_4990689_7 Glycosyltransferase family 10 (fucosyltransferase) C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 363.0
REGS1_k127_4990689_8 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 329.0
REGS1_k127_4990689_9 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001509 229.0
REGS1_k127_4997984_0 Transposase DDE domain - - - 6.567e-265 826.0
REGS1_k127_4997984_1 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 514.0
REGS1_k127_4997984_2 Methyltransferase domain - - - 0.00000000000000000000000007537 115.0
REGS1_k127_5024205_0 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 597.0
REGS1_k127_5024205_1 PFAM major facilitator superfamily MFS_1 K19577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 595.0
REGS1_k127_5024205_2 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000002045 201.0
REGS1_k127_5024205_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000002473 128.0
REGS1_k127_5059097_0 Sugar (and other) transporter - - - 1.425e-242 755.0
REGS1_k127_5059097_1 BRO family, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 292.0
REGS1_k127_5059097_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 288.0
REGS1_k127_5059097_3 - - - - 0.000000000000000000000000000000000000000000000000000000002204 209.0
REGS1_k127_5065232_0 SMART CBS domain containing protein K07182 - - 1.8e-322 996.0
REGS1_k127_5065232_1 Sodium:solute symporter family - - - 2.535e-291 908.0
REGS1_k127_5065232_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 480.0
REGS1_k127_5065232_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 478.0
REGS1_k127_5065232_4 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 393.0
REGS1_k127_5065232_5 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 332.0
REGS1_k127_5065232_6 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000002097 218.0
REGS1_k127_5065232_7 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000000000000000000003625 188.0
REGS1_k127_5065232_8 - - - - 0.000000000000000000000000000000000000000000009024 180.0
REGS1_k127_5103333_0 Carbohydrate-selective porin, OprB family - - - 4.079e-211 663.0
REGS1_k127_5103333_1 ABC-type uncharacterized transport system - - - 3.046e-195 617.0
REGS1_k127_5103333_10 - - - - 0.0000001587 55.0
REGS1_k127_5103333_2 TOBE-like domain K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 563.0
REGS1_k127_5103333_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 475.0
REGS1_k127_5103333_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 417.0
REGS1_k127_5103333_5 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 349.0
REGS1_k127_5103333_6 Transcriptional regulator K13634,K13635 GO:0006792,GO:0008150,GO:0045883,GO:0048518,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 335.0
REGS1_k127_5103333_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 312.0
REGS1_k127_5103333_8 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000007431 149.0
REGS1_k127_5125370_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1112.0
REGS1_k127_5125370_1 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 1.864e-218 683.0
REGS1_k127_5143758_0 Diguanylate cyclase - - - 3.007e-265 848.0
REGS1_k127_5143758_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 291.0
REGS1_k127_5143758_2 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006226 241.0
REGS1_k127_5188957_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.048e-258 806.0
REGS1_k127_5188957_1 Peptidase family M23 - - - 1.826e-207 653.0
REGS1_k127_5188957_10 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000004631 203.0
REGS1_k127_5188957_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.936e-205 647.0
REGS1_k127_5188957_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 4.478e-200 625.0
REGS1_k127_5188957_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 585.0
REGS1_k127_5188957_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 323.0
REGS1_k127_5188957_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 293.0
REGS1_k127_5188957_7 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 291.0
REGS1_k127_5188957_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001912 242.0
REGS1_k127_5188957_9 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000000000006488 228.0
REGS1_k127_5242969_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 564.0
REGS1_k127_5242969_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 481.0
REGS1_k127_5242969_2 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 305.0
REGS1_k127_5242969_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000009133 235.0
REGS1_k127_5242969_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000003145 235.0
REGS1_k127_5242969_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000003894 245.0
REGS1_k127_5242969_6 Peptidoglycan-synthase activator LpoB - - - 0.000000000000000000000000000000000000000000000000000000000006801 213.0
REGS1_k127_5242969_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000002809 195.0
REGS1_k127_5242969_8 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.000000000000000000000000000000000000000001928 179.0
REGS1_k127_5242969_9 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000651 62.0
REGS1_k127_5251109_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1060.0
REGS1_k127_5251109_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.631e-248 769.0
REGS1_k127_5251109_2 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 541.0
REGS1_k127_5251109_3 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000003935 185.0
REGS1_k127_5251109_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000004913 124.0
REGS1_k127_5258622_0 TIGRFAM PAS sensor protein - - - 4.182e-195 621.0
REGS1_k127_5258622_1 membrane K08994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 495.0
REGS1_k127_5258622_2 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000002483 94.0
REGS1_k127_5261056_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1091.0
REGS1_k127_5261056_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 299.0
REGS1_k127_5261056_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000001151 153.0
REGS1_k127_5261056_3 Flagellar regulator YcgR - - - 0.000000000000001266 85.0
REGS1_k127_532202_0 LysR substrate binding domain K13634,K13635 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 344.0
REGS1_k127_532202_1 SIR2-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 322.0
REGS1_k127_532202_2 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000002643 154.0
REGS1_k127_5330079_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1236.0
REGS1_k127_5330079_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 2.435e-251 782.0
REGS1_k127_5330079_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 531.0
REGS1_k127_5330079_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 456.0
REGS1_k127_5330079_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 312.0
REGS1_k127_5330079_5 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000000000000000000001843 227.0
REGS1_k127_5330079_6 Protein of unknown function (DUF2782) - - - 0.00000000000000000000000000000000000001881 146.0
REGS1_k127_5392492_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1775.0
REGS1_k127_5392492_1 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases K01153 - 3.1.21.3 0.0 1322.0
REGS1_k127_5392492_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 316.0
REGS1_k127_5392492_11 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000126 282.0
REGS1_k127_5392492_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003894 262.0
REGS1_k127_5392492_13 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001431 252.0
REGS1_k127_5392492_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007172 246.0
REGS1_k127_5392492_15 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000001551 259.0
REGS1_k127_5392492_16 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006424 243.0
REGS1_k127_5392492_17 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003307 238.0
REGS1_k127_5392492_18 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000000000002435 237.0
REGS1_k127_5392492_19 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000000000003965 232.0
REGS1_k127_5392492_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.419e-263 812.0
REGS1_k127_5392492_20 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000001655 205.0
REGS1_k127_5392492_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000002162 183.0
REGS1_k127_5392492_22 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000000000000001587 180.0
REGS1_k127_5392492_23 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000003042 150.0
REGS1_k127_5392492_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000007748 145.0
REGS1_k127_5392492_25 PFAM CcdB protein K19163 - - 0.0000000000000000000000000000000001096 136.0
REGS1_k127_5392492_26 - - - - 0.0000000000000000000000000000000004443 136.0
REGS1_k127_5392492_27 - - - - 0.0000000000000000000000000455 116.0
REGS1_k127_5392492_28 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000000000000002636 106.0
REGS1_k127_5392492_29 Ribosomal protein L30p/L7e K02907 - - 0.00000000000000000000002826 99.0
REGS1_k127_5392492_3 HsdM N-terminal domain K03427 - 2.1.1.72 5.465e-251 785.0
REGS1_k127_5392492_30 Protein of unknown function (DUF1778) - - - 0.0000000000000000000001744 99.0
REGS1_k127_5392492_31 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid K19164 - - 0.0000000000000000000021 96.0
REGS1_k127_5392492_33 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000009852 78.0
REGS1_k127_5392492_34 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000618 51.0
REGS1_k127_5392492_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 589.0
REGS1_k127_5392492_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 541.0
REGS1_k127_5392492_6 BRO family, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 452.0
REGS1_k127_5392492_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 387.0
REGS1_k127_5392492_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 343.0
REGS1_k127_5392492_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 317.0
REGS1_k127_5507122_0 ATPases associated with a variety of cellular activities - - - 0.0 1227.0
REGS1_k127_5507122_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 9.528e-225 700.0
REGS1_k127_5507122_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 531.0
REGS1_k127_5507122_3 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000001944 199.0
REGS1_k127_5507122_4 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.000001126 57.0
REGS1_k127_5566877_0 general secretion pathway protein D K02453 - - 1.279e-267 841.0
REGS1_k127_5566877_1 type II secretion system protein E K02454,K02652,K12276 - - 1.957e-261 812.0
REGS1_k127_5566877_2 PFAM Type II secretion system F domain K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 327.0
REGS1_k127_5566877_3 general secretion pathway protein G K02456 - - 0.0000000000000000000000000007058 114.0
REGS1_k127_5591412_0 PFAM polysaccharide biosynthesis protein CapD - - - 9.126e-307 951.0
REGS1_k127_5591412_1 PFAM Glycosyl transferase, family 4, conserved region K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 527.0
REGS1_k127_5591412_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 317.0
REGS1_k127_5591412_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 309.0
REGS1_k127_5591412_4 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001366 277.0
REGS1_k127_5591412_5 O-Antigen ligase K02847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005646 287.0
REGS1_k127_5591412_6 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000001782 99.0
REGS1_k127_5618400_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.222e-266 824.0
REGS1_k127_5618400_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 2.057e-227 707.0
REGS1_k127_5618400_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 438.0
REGS1_k127_5666944_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 428.0
REGS1_k127_5666944_1 glutathione transferase activity K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003918 280.0
REGS1_k127_5666944_2 Two component transcriptional regulator, winged helix family K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001298 280.0
REGS1_k127_5666944_3 His Kinase A (phosphoacceptor) domain K07641 - 2.7.13.3 0.00000000000000000000004906 102.0
REGS1_k127_569609_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.789e-223 693.0
REGS1_k127_569609_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 7.546e-216 673.0
REGS1_k127_569609_10 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 340.0
REGS1_k127_569609_11 cyclic nucleotide binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003022 241.0
REGS1_k127_569609_12 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000001293 208.0
REGS1_k127_569609_13 - - - - 0.000000000000000000000001323 104.0
REGS1_k127_569609_2 PFAM type II secretion system protein E K02670 - - 6.025e-209 654.0
REGS1_k127_569609_3 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 1.357e-206 653.0
REGS1_k127_569609_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 525.0
REGS1_k127_569609_5 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 477.0
REGS1_k127_569609_6 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 457.0
REGS1_k127_569609_7 AAA domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 408.0
REGS1_k127_569609_8 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 401.0
REGS1_k127_569609_9 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 389.0
REGS1_k127_5737587_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1551.0
REGS1_k127_5737587_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1189.0
REGS1_k127_5737587_10 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 364.0
REGS1_k127_5737587_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 330.0
REGS1_k127_5737587_12 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 311.0
REGS1_k127_5737587_13 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 287.0
REGS1_k127_5737587_14 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000000000000006277 172.0
REGS1_k127_5737587_15 Frataxin-like domain K06202 - - 0.00000000000000000000000000000000000001436 147.0
REGS1_k127_5737587_16 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000005214 132.0
REGS1_k127_5737587_2 MgtE intracellular N domain K06213 - - 3.242e-267 828.0
REGS1_k127_5737587_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 6.135e-236 738.0
REGS1_k127_5737587_4 histidine kinase HAMP region domain protein K07711 - 2.7.13.3 3.442e-196 621.0
REGS1_k127_5737587_5 aspartic-type endopeptidase activity K06202,K06985,K19054 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 520.0
REGS1_k127_5737587_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 437.0
REGS1_k127_5737587_7 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 418.0
REGS1_k127_5737587_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 409.0
REGS1_k127_5737587_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 374.0
REGS1_k127_5777543_0 AAA domain - - - 8.965e-201 639.0
REGS1_k127_5777543_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 393.0
REGS1_k127_5777543_2 PFAM type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009463 331.0
REGS1_k127_5801944_0 Butirosin biosynthesis protein H, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 564.0
REGS1_k127_5801944_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 318.0
REGS1_k127_5801944_2 Acyl carrier protein phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
REGS1_k127_5801944_3 - - - - 0.00000000000000000000000000000000000000000000000000002378 197.0
REGS1_k127_5810593_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 444.0
REGS1_k127_5810593_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008025 239.0
REGS1_k127_5810593_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000009715 208.0
REGS1_k127_5823864_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 4.926e-237 736.0
REGS1_k127_5823864_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 601.0
REGS1_k127_5823864_10 Amino-transferase class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 263.0
REGS1_k127_5823864_11 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004609 252.0
REGS1_k127_5823864_12 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000001783 196.0
REGS1_k127_5823864_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000001384 139.0
REGS1_k127_5823864_14 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000001123 123.0
REGS1_k127_5823864_15 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000005625 126.0
REGS1_k127_5823864_16 diguanylate cyclase - - - 0.00000000002808 64.0
REGS1_k127_5823864_17 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000001174 69.0
REGS1_k127_5823864_2 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 572.0
REGS1_k127_5823864_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 565.0
REGS1_k127_5823864_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 542.0
REGS1_k127_5823864_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 460.0
REGS1_k127_5823864_6 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 444.0
REGS1_k127_5823864_7 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 441.0
REGS1_k127_5823864_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 353.0
REGS1_k127_5823864_9 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000209 281.0
REGS1_k127_5827783_0 type II secretion system protein E K02454,K02652,K12276 - - 1.909e-241 757.0
REGS1_k127_5827783_1 Secretin and TonB N terminus short domain K02453 - - 2.132e-229 732.0
REGS1_k127_5827783_2 PFAM type II secretion system K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 470.0
REGS1_k127_5827783_3 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000001623 222.0
REGS1_k127_5827783_4 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000000000000000000000008996 200.0
REGS1_k127_5827783_5 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000002082 159.0
REGS1_k127_5827783_6 Type II secretory pathway, pseudopilin - - - 0.000000000000000000000000000000000000000002525 161.0
REGS1_k127_5827783_7 - - - - 0.0000000000000000000000000000000001443 143.0
REGS1_k127_5827783_8 carbon utilization - - - 0.0000000000000000000000000000000003521 138.0
REGS1_k127_5827783_9 - - - - 0.0000000000000000000003887 102.0
REGS1_k127_5836509_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 4.483e-250 776.0
REGS1_k127_5836509_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 5.881e-250 771.0
REGS1_k127_5836509_2 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 3.888e-244 762.0
REGS1_k127_5836509_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000005151 158.0
REGS1_k127_5836509_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000005563 113.0
REGS1_k127_5881064_0 fibronectin type III domain protein K06882 - - 0.0 1331.0
REGS1_k127_5881064_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 4.639e-303 942.0
REGS1_k127_5881064_10 Transposase and inactivated derivatives - - - 0.0001373 48.0
REGS1_k127_5881064_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.119e-227 706.0
REGS1_k127_5881064_3 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 501.0
REGS1_k127_5881064_4 Protein of unknown function (DUF3800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001412 280.0
REGS1_k127_5881064_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004582 271.0
REGS1_k127_5881064_6 sequence-specific DNA binding K18830 - - 0.00000000000000000000000000000000000000007551 160.0
REGS1_k127_5881064_9 - - - - 0.000001117 52.0
REGS1_k127_5907932_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.944e-243 752.0
REGS1_k127_5907932_1 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 548.0
REGS1_k127_5907932_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 441.0
REGS1_k127_5907932_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002348 243.0
REGS1_k127_5907932_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003922 209.0
REGS1_k127_5907932_5 - - - - 0.00005615 53.0
REGS1_k127_5930683_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1077.0
REGS1_k127_5930683_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 4.272e-206 645.0
REGS1_k127_5930683_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 564.0
REGS1_k127_5930683_3 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 546.0
REGS1_k127_5930683_4 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 448.0
REGS1_k127_5930683_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 364.0
REGS1_k127_5930683_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000000009153 178.0
REGS1_k127_5930683_7 Pfam:DUF1049 K08992 - - 0.00000000000000000000000000000002823 129.0
REGS1_k127_5950962_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.0 1097.0
REGS1_k127_5950962_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.902e-259 804.0
REGS1_k127_5950962_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001182 259.0
REGS1_k127_5950962_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004822 239.0
REGS1_k127_5950962_4 general secretion pathway protein - - - 0.0000000000000000000000000000000000000000000000000000005326 201.0
REGS1_k127_5950962_5 - - - - 0.000000000000000000000000000000000000000263 166.0
REGS1_k127_5950962_6 - - - - 0.00000000000000000000000000000001053 128.0
REGS1_k127_5950962_7 - - - - 0.0000000000000000000000000007803 119.0
REGS1_k127_5950962_8 Universal stress protein family - - - 0.0000000000000000000000000138 119.0
REGS1_k127_5952321_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 542.0
REGS1_k127_5952321_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 374.0
REGS1_k127_5952321_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 336.0
REGS1_k127_5952321_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000281 169.0
REGS1_k127_5952321_4 in signal transduction K08482 - - 0.0000000000000000000002054 98.0
REGS1_k127_5971165_0 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 613.0
REGS1_k127_5971165_1 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 586.0
REGS1_k127_5971165_10 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000004539 129.0
REGS1_k127_5971165_11 Type II secretory pathway pseudopilin - - - 0.00000000000000000000000002755 115.0
REGS1_k127_5971165_12 Transcriptional regulator - - - 0.00000000000000000006787 89.0
REGS1_k127_5971165_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000005712 86.0
REGS1_k127_5971165_14 Phenazine biosynthesis-like protein - - - 0.0000000000005831 69.0
REGS1_k127_5971165_2 Bacterial type II and III secretion system protein K02453,K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 370.0
REGS1_k127_5971165_3 surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 327.0
REGS1_k127_5971165_4 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000679 269.0
REGS1_k127_5971165_5 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000005134 235.0
REGS1_k127_5971165_6 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000655 231.0
REGS1_k127_5971165_7 Protein of unknown function (DUF1304) K08987 - - 0.00000000000000000000000000000000000000000000009612 170.0
REGS1_k127_5971165_8 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000003603 160.0
REGS1_k127_5971165_9 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000006665 142.0
REGS1_k127_5993829_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.024e-294 908.0
REGS1_k127_5993829_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 580.0
REGS1_k127_5993829_2 PFAM import inner membrane translocase subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 326.0
REGS1_k127_6028231_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1397.0
REGS1_k127_6028231_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 5.87e-300 927.0
REGS1_k127_6028231_10 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 383.0
REGS1_k127_6028231_11 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 405.0
REGS1_k127_6028231_12 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 374.0
REGS1_k127_6028231_13 bacterial-type flagellum organization K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 322.0
REGS1_k127_6028231_14 PFAM porin Gram-negative type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 309.0
REGS1_k127_6028231_15 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 301.0
REGS1_k127_6028231_16 Outer membrane protein (Porin) K03285 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001935 290.0
REGS1_k127_6028231_17 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002135 252.0
REGS1_k127_6028231_18 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002664 249.0
REGS1_k127_6028231_19 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008969 243.0
REGS1_k127_6028231_2 Virulence factor membrane-bound polymerase, C-terminal - - - 5.021e-278 865.0
REGS1_k127_6028231_20 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000003528 194.0
REGS1_k127_6028231_21 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000001345 178.0
REGS1_k127_6028231_22 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000006361 145.0
REGS1_k127_6028231_23 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000001616 142.0
REGS1_k127_6028231_24 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000001005 145.0
REGS1_k127_6028231_25 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000003698 123.0
REGS1_k127_6028231_26 Rhodanese Homology Domain - - - 0.00000000000000000000000002188 113.0
REGS1_k127_6028231_27 - - - - 0.000000000000000000001978 98.0
REGS1_k127_6028231_28 Protein of unknown function (DUF2892) - - - 0.0000000000000000005288 91.0
REGS1_k127_6028231_3 Beta-lactamase - - - 2.037e-273 851.0
REGS1_k127_6028231_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 9.334e-232 722.0
REGS1_k127_6028231_5 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 456.0
REGS1_k127_6028231_6 Polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 416.0
REGS1_k127_6028231_7 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 400.0
REGS1_k127_6028231_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 394.0
REGS1_k127_6028231_9 Involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 402.0
REGS1_k127_6037035_0 KaiC K08482 - - 2.121e-238 748.0
REGS1_k127_6037035_1 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 400.0
REGS1_k127_6037035_2 KaiB domain K08481 - - 0.00000000000000000000000000000001129 132.0
REGS1_k127_6049971_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.728e-264 819.0
REGS1_k127_6049971_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 401.0
REGS1_k127_6049971_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000009739 219.0
REGS1_k127_6049971_3 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000006092 189.0
REGS1_k127_6049971_4 - - - - 0.000000000000000000000004691 104.0
REGS1_k127_6084125_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1077.0
REGS1_k127_6084125_1 Pfam Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000001297 219.0
REGS1_k127_6084125_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000002238 96.0
REGS1_k127_6128533_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 3.741e-216 675.0
REGS1_k127_6128533_1 PFAM AIR synthase related protein domain protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 435.0
REGS1_k127_6128533_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000002217 240.0
REGS1_k127_6128533_3 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000002087 162.0
REGS1_k127_6128533_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000003004 115.0
REGS1_k127_6128533_6 Nucleotidyl transferase K00992 - 2.7.7.99 0.000003373 51.0
REGS1_k127_6140012_0 Histidine kinase K02482 - 2.7.13.3 1.362e-229 719.0
REGS1_k127_6140012_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 498.0
REGS1_k127_6140012_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 382.0
REGS1_k127_6140012_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 322.0
REGS1_k127_6140012_5 Uncharacterized conserved protein (DUF2164) - - - 0.00000000000000000000000000000007613 128.0
REGS1_k127_6140012_6 Domain of unknown function (DUF4149) - - - 0.0000000000000000000007301 96.0
REGS1_k127_618400_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1709.0
REGS1_k127_618400_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1275.0
REGS1_k127_618400_2 LysM domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 613.0
REGS1_k127_618400_3 TIGRFAM efflux transporter, RND family, MFP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 477.0
REGS1_k127_618400_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 479.0
REGS1_k127_618400_5 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 247.0
REGS1_k127_618400_6 Protein of unknown function (DUF3240) - - - 0.0000000000000000000000000000000000000000000000000005756 186.0
REGS1_k127_618400_7 PQ loop repeat K15383 - - 0.0000000000000000000000000000000004052 134.0
REGS1_k127_6185896_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 1.654e-304 942.0
REGS1_k127_6185896_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 392.0
REGS1_k127_6185896_3 OmpA-like transmembrane domain - - - 0.0001383 51.0
REGS1_k127_6217246_0 pteridine-dependent deoxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 486.0
REGS1_k127_6217246_1 fad dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 438.0
REGS1_k127_6217246_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 388.0
REGS1_k127_6217246_3 Glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 375.0
REGS1_k127_6223019_0 K+ potassium transporter K03549 - - 4.651e-263 818.0
REGS1_k127_6223019_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 3.437e-255 791.0
REGS1_k127_6223019_10 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000002631 221.0
REGS1_k127_6223019_11 - - - - 0.00000000000000000000000000000000000000000000000000000005357 199.0
REGS1_k127_6223019_12 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000000001107 140.0
REGS1_k127_6223019_13 - - - - 0.0000000000000000002832 89.0
REGS1_k127_6223019_2 - - - - 2.416e-202 642.0
REGS1_k127_6223019_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 569.0
REGS1_k127_6223019_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 366.0
REGS1_k127_6223019_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 369.0
REGS1_k127_6223019_6 Protein of unknown function (DUF615) K09889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 310.0
REGS1_k127_6223019_7 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 284.0
REGS1_k127_6223019_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001423 275.0
REGS1_k127_6223019_9 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000002579 216.0
REGS1_k127_6244379_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004782 262.0
REGS1_k127_6244379_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004951 258.0
REGS1_k127_6244379_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000005766 216.0
REGS1_k127_6244379_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000002798 162.0
REGS1_k127_6244379_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000157 153.0
REGS1_k127_6244379_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000001064 130.0
REGS1_k127_6244379_6 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000001264 120.0
REGS1_k127_6244379_7 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000006981 90.0
REGS1_k127_6244379_8 protein conserved in bacteria - - - 0.00000000000009804 78.0
REGS1_k127_6244379_9 - - - - 0.000000000001636 79.0
REGS1_k127_6245349_0 cytochrome C peroxidase - - - 8.647e-252 782.0
REGS1_k127_6245349_1 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 448.0
REGS1_k127_6245349_2 water channel activity K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 381.0
REGS1_k127_6245349_3 PFAM NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 310.0
REGS1_k127_6245349_4 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000061 121.0
REGS1_k127_6245349_5 Protein of unknown function (DUF3309) - - - 0.000000000000000000002795 94.0
REGS1_k127_6245349_6 Domain of unknown function (DUF4398) - - - 0.000000000000000002091 85.0
REGS1_k127_6245349_7 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000004377 74.0
REGS1_k127_6254014_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1244.0
REGS1_k127_6254014_1 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1029.0
REGS1_k127_6254014_10 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 437.0
REGS1_k127_6254014_11 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 350.0
REGS1_k127_6254014_12 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 327.0
REGS1_k127_6254014_13 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 320.0
REGS1_k127_6254014_14 transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 313.0
REGS1_k127_6254014_15 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 250.0
REGS1_k127_6254014_16 PFAM Sporulation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002186 241.0
REGS1_k127_6254014_17 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000000000006069 233.0
REGS1_k127_6254014_18 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000007403 224.0
REGS1_k127_6254014_19 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008364 215.0
REGS1_k127_6254014_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 6.304e-310 970.0
REGS1_k127_6254014_20 - - - - 0.000000000000000000000001458 104.0
REGS1_k127_6254014_3 Malate:quinone oxidoreductase (Mqo) K00116 - 1.1.5.4 4.616e-271 839.0
REGS1_k127_6254014_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 4.889e-259 807.0
REGS1_k127_6254014_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.082e-253 786.0
REGS1_k127_6254014_6 Major Facilitator Superfamily K08227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 604.0
REGS1_k127_6254014_7 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 572.0
REGS1_k127_6254014_8 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 486.0
REGS1_k127_6254014_9 S4 RNA-binding domain K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 451.0
REGS1_k127_6281417_0 B3/4 domain K01890 - 6.1.1.20 0.0 1264.0
REGS1_k127_6281417_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 1.112e-208 649.0
REGS1_k127_6281417_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 583.0
REGS1_k127_6281417_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000002371 212.0
REGS1_k127_6281417_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000000000005595 199.0
REGS1_k127_6281417_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000001537 183.0
REGS1_k127_6281417_6 transcriptional - - - 0.000000000000000000000000000000000000000000001518 167.0
REGS1_k127_6281417_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000003636 115.0
REGS1_k127_6283394_0 PFAM ABC transporter related - - - 0.0 1008.0
REGS1_k127_6283394_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 3.315e-284 890.0
REGS1_k127_6283394_10 - - - - 0.00000000000000000000000000000000000000000000000003405 183.0
REGS1_k127_6283394_11 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000000002204 180.0
REGS1_k127_6283394_12 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000001616 151.0
REGS1_k127_6283394_13 - - - - 0.00000000000000000000000000000000006365 136.0
REGS1_k127_6283394_15 - - - - 0.00000000002074 73.0
REGS1_k127_6283394_17 - - - - 0.0000352 53.0
REGS1_k127_6283394_2 Glutamate-cysteine ligase K01919 - 6.3.2.2 2.123e-252 782.0
REGS1_k127_6283394_3 Diguanylate cyclase - - - 6.737e-251 785.0
REGS1_k127_6283394_4 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 554.0
REGS1_k127_6283394_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 533.0
REGS1_k127_6283394_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 380.0
REGS1_k127_6283394_7 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 369.0
REGS1_k127_6283394_8 esterase of the alpha beta hydrolase fold K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 323.0
REGS1_k127_6283394_9 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 314.0
REGS1_k127_6368054_0 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 1.413e-203 638.0
REGS1_k127_6368054_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 382.0
REGS1_k127_6368054_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000009188 227.0
REGS1_k127_6413827_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 2.755e-297 917.0
REGS1_k127_6413827_1 - - - - 9.117e-293 914.0
REGS1_k127_6413827_10 NlpC/P60 family K19303 - - 0.0000000000000000000000000000000000000000000000000000000000000001298 224.0
REGS1_k127_6413827_11 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000001134 207.0
REGS1_k127_6413827_12 Dienelactone hydrolase - - - 0.000000000000000000000000000000000000005249 146.0
REGS1_k127_6413827_13 - - - - 0.0000000000000000000000000000000000002232 145.0
REGS1_k127_6413827_14 Antitoxin component of bacterial toxin-antitoxin system, MqsA - - - 0.00000000000000000000000000001546 126.0
REGS1_k127_6413827_15 - - - - 0.00000000000006685 83.0
REGS1_k127_6413827_2 RmuC family K09760 - - 5.907e-221 691.0
REGS1_k127_6413827_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 586.0
REGS1_k127_6413827_4 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 466.0
REGS1_k127_6413827_5 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 451.0
REGS1_k127_6413827_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 432.0
REGS1_k127_6413827_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 370.0
REGS1_k127_6413827_8 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 349.0
REGS1_k127_6413827_9 Smr domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001315 276.0
REGS1_k127_6427801_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 6.666e-210 659.0
REGS1_k127_6427801_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 521.0
REGS1_k127_6427801_2 glycosyl - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 383.0
REGS1_k127_6427801_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 342.0
REGS1_k127_6427801_4 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000000005591 197.0
REGS1_k127_6427801_5 cytochrome - - - 0.00000000000000000000000000002037 128.0
REGS1_k127_6427801_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000001059 106.0
REGS1_k127_6457885_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1423.0
REGS1_k127_6457885_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 9.549e-215 671.0
REGS1_k127_6457885_2 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 553.0
REGS1_k127_6457885_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000002513 109.0
REGS1_k127_6536370_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1043.0
REGS1_k127_6536370_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K03815 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 548.0
REGS1_k127_6536370_2 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 363.0
REGS1_k127_6536370_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 332.0
REGS1_k127_6536370_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000004298 237.0
REGS1_k127_6558531_0 TIGRFAM ATP-dependent Clp protease, ATP-binding subunit clpA K03694 - - 0.0 1098.0
REGS1_k127_6558531_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 315.0
REGS1_k127_6558531_2 - - - - 0.0000000000000000000000000000000000000000000000000006917 187.0
REGS1_k127_6629651_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 3.247e-249 773.0
REGS1_k127_6629651_1 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 3.03e-212 665.0
REGS1_k127_6629651_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000000001471 237.0
REGS1_k127_6653254_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 7.063e-239 741.0
REGS1_k127_6653254_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 608.0
REGS1_k127_6653254_10 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000005828 228.0
REGS1_k127_6653254_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 600.0
REGS1_k127_6653254_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 473.0
REGS1_k127_6653254_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 462.0
REGS1_k127_6653254_5 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 384.0
REGS1_k127_6653254_6 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 358.0
REGS1_k127_6653254_7 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 358.0
REGS1_k127_6653254_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 332.0
REGS1_k127_6653254_9 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 272.0
REGS1_k127_6655185_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1432.0
REGS1_k127_6655185_1 Pfam Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 605.0
REGS1_k127_6655185_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 299.0
REGS1_k127_6655185_3 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 297.0
REGS1_k127_6655185_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002419 245.0
REGS1_k127_6655185_5 TIR domain - - - 0.0000000000000000000000001181 107.0
REGS1_k127_67202_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 336.0
REGS1_k127_67202_2 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000000000000000006617 137.0
REGS1_k127_6722098_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1461.0
REGS1_k127_6722098_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1375.0
REGS1_k127_6722098_10 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 499.0
REGS1_k127_6722098_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 448.0
REGS1_k127_6722098_12 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 383.0
REGS1_k127_6722098_13 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 379.0
REGS1_k127_6722098_14 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 316.0
REGS1_k127_6722098_15 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 286.0
REGS1_k127_6722098_16 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001576 260.0
REGS1_k127_6722098_17 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005691 243.0
REGS1_k127_6722098_18 Cytochrome C biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000454 213.0
REGS1_k127_6722098_19 MazG-like family - - - 0.00000000000000000000000000000000000000000000000006734 183.0
REGS1_k127_6722098_2 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1165.0
REGS1_k127_6722098_20 ROK family K00845 - 2.7.1.2 0.00000000000000000000000001513 111.0
REGS1_k127_6722098_21 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.00000000000001832 82.0
REGS1_k127_6722098_22 - - - - 0.0000000005444 63.0
REGS1_k127_6722098_3 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0 1099.0
REGS1_k127_6722098_4 Asparagine synthase K01953 - 6.3.5.4 4.48e-309 954.0
REGS1_k127_6722098_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.492e-252 781.0
REGS1_k127_6722098_6 SurA N-terminal domain K03770 - 5.2.1.8 2.867e-244 769.0
REGS1_k127_6722098_7 PFAM aminotransferase class I and II K00812 - 2.6.1.1 5.108e-232 721.0
REGS1_k127_6722098_8 translation initiation factor activity - - - 2.546e-229 741.0
REGS1_k127_6722098_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.082e-220 689.0
REGS1_k127_6723_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1566.0
REGS1_k127_6723_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 3.667e-226 703.0
REGS1_k127_6723_2 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 1.173e-202 635.0
REGS1_k127_6723_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 499.0
REGS1_k127_6723_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 407.0
REGS1_k127_6735971_0 Histidine Phosphotransfer domain K02487,K06596 - - 0.0 1936.0
REGS1_k127_6735971_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.033e-270 838.0
REGS1_k127_6735971_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001879 250.0
REGS1_k127_6735971_11 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000002276 225.0
REGS1_k127_6735971_12 peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000008566 233.0
REGS1_k127_6735971_13 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000000000000000000000000000073 203.0
REGS1_k127_6735971_14 response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000007654 165.0
REGS1_k127_6735971_15 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000001793 122.0
REGS1_k127_6735971_2 PFAM TrkA-N domain protein K03499 - - 1.644e-249 779.0
REGS1_k127_6735971_3 histidine kinase HAMP region domain protein K02660,K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 627.0
REGS1_k127_6735971_4 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 597.0
REGS1_k127_6735971_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 370.0
REGS1_k127_6735971_6 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 372.0
REGS1_k127_6735971_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 349.0
REGS1_k127_6735971_8 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 342.0
REGS1_k127_6735971_9 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 326.0
REGS1_k127_6737056_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 3.992e-273 850.0
REGS1_k127_6737056_1 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 476.0
REGS1_k127_6737056_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 339.0
REGS1_k127_6737056_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000002972 99.0
REGS1_k127_6775323_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.18e-316 971.0
REGS1_k127_6775323_1 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 7.04e-255 790.0
REGS1_k127_6775323_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 524.0
REGS1_k127_6775323_3 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001753 244.0
REGS1_k127_6775323_4 Sporulation related domain K03749 - - 0.000000000000000000000000000000000000000000000000000000006351 205.0
REGS1_k127_6775323_5 - - - - 0.0000000000000006124 79.0
REGS1_k127_685665_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1530.0
REGS1_k127_685665_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
REGS1_k127_68825_0 Belongs to the peptidase M16 family K07263 - - 8.93e-222 694.0
REGS1_k127_68825_1 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 597.0
REGS1_k127_68825_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 533.0
REGS1_k127_68825_3 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 420.0
REGS1_k127_68825_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 287.0
REGS1_k127_68825_5 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000007138 211.0
REGS1_k127_6890810_0 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 2.915e-251 781.0
REGS1_k127_6890810_1 HI0933-like protein K07007 - - 5.892e-204 643.0
REGS1_k127_6890810_10 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000177 246.0
REGS1_k127_6890810_11 PFAM HPP family protein K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000005111 241.0
REGS1_k127_6890810_12 YdjC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001032 246.0
REGS1_k127_6890810_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002557 233.0
REGS1_k127_6890810_14 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000001949 197.0
REGS1_k127_6890810_15 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000000001681 185.0
REGS1_k127_6890810_17 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000008376 166.0
REGS1_k127_6890810_18 Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000000000000000000000002486 166.0
REGS1_k127_6890810_19 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000003511 145.0
REGS1_k127_6890810_2 PFAM UMUC domain protein DNA-repair protein K03502 - - 1.765e-202 642.0
REGS1_k127_6890810_20 GtrA-like protein - - - 0.000000000000000000000000000000000004593 141.0
REGS1_k127_6890810_21 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000103 131.0
REGS1_k127_6890810_22 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000003624 127.0
REGS1_k127_6890810_23 - - - - 0.0000000000000000000000000000001553 130.0
REGS1_k127_6890810_3 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 481.0
REGS1_k127_6890810_4 PFAM Peptidase S24 S26A S26B, conserved region K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 339.0
REGS1_k127_6890810_5 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 281.0
REGS1_k127_6890810_6 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001266 278.0
REGS1_k127_6890810_7 PFAM Peptidase S24 S26A S26B, conserved region K03503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003925 269.0
REGS1_k127_6890810_8 DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005278 271.0
REGS1_k127_6890810_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002162 267.0
REGS1_k127_6899975_0 Protein of unknown function, DUF255 K06888 - - 0.0 1126.0
REGS1_k127_6899975_1 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 301.0
REGS1_k127_6909480_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1210.0
REGS1_k127_6909480_1 surface antigen - - - 0.0 1172.0
REGS1_k127_6909480_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 543.0
REGS1_k127_6919951_0 ABC transporter transmembrane region K06147,K06148 - - 0.0 1138.0
REGS1_k127_6919951_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.94e-228 718.0
REGS1_k127_6919951_2 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 1.1e-224 702.0
REGS1_k127_6919951_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 448.0
REGS1_k127_6919951_4 Domain of unknown function (DUF1854) - - - 0.0000000000000000000000000000000000000000000000001338 181.0
REGS1_k127_6919951_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000000000009475 166.0
REGS1_k127_6919951_6 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000000001645 138.0
REGS1_k127_7017497_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1072.0
REGS1_k127_7017497_1 Polysulphide reductase, NrfD K00185 - - 6.748e-281 866.0
REGS1_k127_7017497_2 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 523.0
REGS1_k127_7017497_3 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 507.0
REGS1_k127_7017497_4 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 456.0
REGS1_k127_7017497_5 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 396.0
REGS1_k127_7017497_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 335.0
REGS1_k127_7017497_7 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 314.0
REGS1_k127_7017497_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002957 250.0
REGS1_k127_7017497_9 - - - - 0.00000000000000000000000000000000000000000000000000000000107 207.0
REGS1_k127_7043812_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.849e-269 831.0
REGS1_k127_7043812_1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 453.0
REGS1_k127_7043812_10 Chitinase class I K03791 - - 0.000000000000000000000000000000000000008259 162.0
REGS1_k127_7043812_11 Antidote-toxin recognition MazE, bacterial antitoxin K07172 - - 0.00000000000000000000000000000001485 127.0
REGS1_k127_7043812_12 Protein of unknown function (DUF2934) - - - 0.000000000000002414 80.0
REGS1_k127_7043812_13 Transposase - - - 0.000000005119 57.0
REGS1_k127_7043812_2 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 434.0
REGS1_k127_7043812_3 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 407.0
REGS1_k127_7043812_4 PFAM Spermine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 388.0
REGS1_k127_7043812_5 Protein of unknown function (DUF2937) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004009 244.0
REGS1_k127_7043812_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002982 239.0
REGS1_k127_7043812_7 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000000000000000000000002455 223.0
REGS1_k127_7043812_8 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000000000000000000000000000002094 194.0
REGS1_k127_7043812_9 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000000000000000000000007649 176.0
REGS1_k127_7069199_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 591.0
REGS1_k127_7069199_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 569.0
REGS1_k127_7069199_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 374.0
REGS1_k127_7069199_3 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 302.0
REGS1_k127_7069199_4 DSBA Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 290.0
REGS1_k127_7084292_0 ABC transporter C-terminal domain K15738 - - 0.0 1094.0
REGS1_k127_7084292_1 Domain of unknown function (DUF3393) K08306 - - 5.143e-201 631.0
REGS1_k127_7084292_10 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000003209 166.0
REGS1_k127_7084292_11 ChrR Cupin-like domain - - - 0.00000000000000000000000000000003387 128.0
REGS1_k127_7084292_12 Domain of unknown function (DUF3330) - - - 0.000000000000543 70.0
REGS1_k127_7084292_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 550.0
REGS1_k127_7084292_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 537.0
REGS1_k127_7084292_4 Rhodanese Homology Domain K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 489.0
REGS1_k127_7084292_5 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 441.0
REGS1_k127_7084292_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 416.0
REGS1_k127_7084292_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 401.0
REGS1_k127_7084292_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 310.0
REGS1_k127_7084292_9 - - - - 0.00000000000000000000000000000000000000000000000000006342 190.0
REGS1_k127_7139231_0 Putative diguanylate phosphodiesterase - - - 0.0 1592.0
REGS1_k127_7139231_1 PFAM CoA-binding domain protein K09181 - - 0.0 1575.0
REGS1_k127_7139231_11 diguanylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005833 260.0
REGS1_k127_7139231_12 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000000000000000000000000000000000007492 216.0
REGS1_k127_7139231_13 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000002227 227.0
REGS1_k127_7139231_14 translation initiation factor activity K08086 - - 0.00000000000000000000000000000000000000000000000000000000001026 231.0
REGS1_k127_7139231_15 PFAM AIR synthase related protein domain protein K04655 - - 0.000000000000000000000000000000000000000000000000000000003254 200.0
REGS1_k127_7139231_16 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000003021 197.0
REGS1_k127_7139231_17 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000009976 171.0
REGS1_k127_7139231_18 - - - - 0.0000000000000000000000000000000000000001985 155.0
REGS1_k127_7139231_19 PFAM heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000005722 132.0
REGS1_k127_7139231_2 PFAM ATP-binding region ATPase domain protein - - - 2.955e-207 656.0
REGS1_k127_7139231_20 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.0000000000000000000006427 98.0
REGS1_k127_7139231_22 Domain of unknown function (DUF4389) - - - 0.0000000000000006732 80.0
REGS1_k127_7139231_3 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 548.0
REGS1_k127_7139231_4 SMART band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008308 544.0
REGS1_k127_7139231_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 419.0
REGS1_k127_7139231_7 protein conserved in bacteria K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 366.0
REGS1_k127_7144304_0 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 0.0 1223.0
REGS1_k127_7144304_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1144.0
REGS1_k127_7144304_10 Regulatory protein, FmdB family - - - 0.00000000000000000000000000003328 118.0
REGS1_k127_7144304_2 TIGRFAM ATP-dependent Clp protease, ATP-binding subunit clpA K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 394.0
REGS1_k127_7144304_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 353.0
REGS1_k127_7144304_4 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 303.0
REGS1_k127_7144304_5 PFAM guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.000000000000000000000000000000000000000000000000000000000009335 210.0
REGS1_k127_7144304_6 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000000241 209.0
REGS1_k127_7144304_7 Barstar (barnase inhibitor) - - - 0.000000000000000000000000000000000000000000000003527 179.0
REGS1_k127_7144304_8 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000003212 171.0
REGS1_k127_7144304_9 SMART Cold shock protein K03704 - - 0.0000000000000000000000000000000000007623 139.0
REGS1_k127_7160083_0 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 609.0
REGS1_k127_7160083_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001263 249.0
REGS1_k127_7160083_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002697 226.0
REGS1_k127_7160083_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000001452 61.0
REGS1_k127_7193005_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 1.87e-223 699.0
REGS1_k127_7193005_1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 4.171e-215 676.0
REGS1_k127_7193005_10 Predicted membrane protein (DUF2335) - - - 0.000000000000203 76.0
REGS1_k127_7193005_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 1.756e-198 619.0
REGS1_k127_7193005_3 Male sterility protein K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 530.0
REGS1_k127_7193005_4 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 381.0
REGS1_k127_7193005_5 Protein of unknown function (DUF1415) K09941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 324.0
REGS1_k127_7193005_6 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
REGS1_k127_7193005_7 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000000000000000000000004782 209.0
REGS1_k127_7193005_8 - - - - 0.000000000000000000000000000000004107 133.0
REGS1_k127_7193005_9 Cupin domain - - - 0.000000000000000000002013 96.0
REGS1_k127_7320971_0 Diguanylate cyclase phosphodiesterase with PAS PAC and GAF sensor(S) - - - 0.0 1306.0
REGS1_k127_7320971_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1286.0
REGS1_k127_7320971_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 283.0
REGS1_k127_7320971_11 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008661 259.0
REGS1_k127_7320971_12 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000007073 226.0
REGS1_k127_7320971_13 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000002229 229.0
REGS1_k127_7320971_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 1.282e-246 763.0
REGS1_k127_7320971_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 606.0
REGS1_k127_7320971_4 Dienelactone hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 480.0
REGS1_k127_7320971_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 449.0
REGS1_k127_7320971_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 415.0
REGS1_k127_7320971_7 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 407.0
REGS1_k127_7320971_8 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 381.0
REGS1_k127_7320971_9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 293.0
REGS1_k127_7364284_0 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 411.0
REGS1_k127_7364284_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 318.0
REGS1_k127_7364284_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 289.0
REGS1_k127_7364284_3 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000000001762 213.0
REGS1_k127_7364284_4 BON domain - - - 0.00000000000000000000000000000000000000000000000006038 183.0
REGS1_k127_7364284_5 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000000000000000001877 149.0
REGS1_k127_7364284_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000001522 133.0
REGS1_k127_7394451_0 PFAM DEAD DEAH box helicase domain protein - - - 2.03e-246 767.0
REGS1_k127_7394451_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 9.034e-218 677.0
REGS1_k127_7394451_10 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000003745 235.0
REGS1_k127_7394451_11 Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000000000000000000000000000000000000000000000000001602 209.0
REGS1_k127_7394451_12 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000000000009072 194.0
REGS1_k127_7394451_13 Diguanylate cyclase - - - 0.0000000000000000000000000000000001625 152.0
REGS1_k127_7394451_14 PFAM plasmid stabilization system - - - 0.000000000000000000000000000007653 118.0
REGS1_k127_7394451_15 - - - - 0.000000000000000000000000005466 117.0
REGS1_k127_7394451_16 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000002453 110.0
REGS1_k127_7394451_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 591.0
REGS1_k127_7394451_3 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 493.0
REGS1_k127_7394451_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 445.0
REGS1_k127_7394451_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 361.0
REGS1_k127_7394451_6 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 351.0
REGS1_k127_7394451_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 337.0
REGS1_k127_7394451_8 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 317.0
REGS1_k127_7394451_9 PAC sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 320.0
REGS1_k127_7409439_0 PAS domain containing protein K07315,K07675 - 2.7.13.3,3.1.3.3 3.526e-270 868.0
REGS1_k127_7409439_1 metal-dependent phosphohydrolase HD sub domain K07814 - - 2.718e-254 792.0
REGS1_k127_7409439_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007886 334.0
REGS1_k127_7409439_3 SMART HTH transcriptional regulator, Crp - - - 0.0000000000000000000000000000000000002261 143.0
REGS1_k127_7409439_4 RNA polymerase sigma K03087 - - 0.000000000000000000000002258 109.0
REGS1_k127_7420461_0 TonB dependent receptor K02014 - - 0.0 1106.0
REGS1_k127_7420461_1 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 559.0
REGS1_k127_7420461_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000005038 228.0
REGS1_k127_7420461_3 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000000000000000000000000344 213.0
REGS1_k127_7420461_4 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000007769 142.0
REGS1_k127_7442971_0 PFAM ABC transporter related K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 561.0
REGS1_k127_7442971_1 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 456.0
REGS1_k127_7442971_2 VanZ like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 454.0
REGS1_k127_7442971_3 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 358.0
REGS1_k127_7442971_4 THUMP K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001246 270.0
REGS1_k127_7442971_5 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002819 261.0
REGS1_k127_7442971_6 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004371 243.0
REGS1_k127_7442971_7 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000006064 190.0
REGS1_k127_7496241_0 Diguanylate cyclase - - - 0.0 1399.0
REGS1_k127_7496241_1 PFAM extracellular solute-binding protein family 1 K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 570.0
REGS1_k127_7496241_2 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 550.0
REGS1_k127_7496241_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 335.0
REGS1_k127_7496241_4 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 321.0
REGS1_k127_7496241_5 - - - - 0.000000000000000000000000000000000001002 141.0
REGS1_k127_7509283_0 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 514.0
REGS1_k127_7509283_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 471.0
REGS1_k127_7509283_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 396.0
REGS1_k127_7509283_3 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006039 270.0
REGS1_k127_7509283_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000002822 224.0
REGS1_k127_7509283_5 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000009296 222.0
REGS1_k127_7509283_6 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000002745 180.0
REGS1_k127_7509283_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000001226 131.0
REGS1_k127_7509283_8 Response regulator, receiver K11443 - - 0.0000000000002456 81.0
REGS1_k127_7509283_9 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0005787 45.0
REGS1_k127_7546250_0 glutamate synthase alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1140.0
REGS1_k127_7546250_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 2.944e-306 942.0
REGS1_k127_7546250_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.334e-211 659.0
REGS1_k127_7546250_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001764 268.0
REGS1_k127_7618660_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 575.0
REGS1_k127_7618660_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 491.0
REGS1_k127_7618660_2 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 340.0
REGS1_k127_7618660_3 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 307.0
REGS1_k127_7618660_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
REGS1_k127_7618660_6 Major Facilitator Superfamily K03446 - - 0.000000000000000000000000000000000000000000000000000000001382 205.0
REGS1_k127_7618660_7 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000008644 202.0
REGS1_k127_7618660_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000918 85.0
REGS1_k127_7693147_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.963e-280 864.0
REGS1_k127_7693147_1 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000000000000009939 139.0
REGS1_k127_7712601_0 - - - - 9.26e-207 647.0
REGS1_k127_7712601_1 Elongator protein 3, MiaB family, Radical SAM - - - 4.914e-196 616.0
REGS1_k127_7712601_2 AAA domain K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000004028 258.0
REGS1_k127_7712601_3 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005445 248.0
REGS1_k127_7712601_4 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008816 231.0
REGS1_k127_7712601_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000005796 112.0
REGS1_k127_7712601_6 K homology RNA-binding domain K16726 GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112 - 0.00000000000000000008522 104.0
REGS1_k127_7712601_7 - - - - 0.0000000001549 66.0
REGS1_k127_7712601_8 Domain of unknown function (DUF4442) - - - 0.00000001488 56.0
REGS1_k127_7797198_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 3.859e-296 910.0
REGS1_k127_7797198_1 Nitrogenase component 1 type Oxidoreductase K02592 - - 7.113e-258 805.0
REGS1_k127_7797198_11 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH - - - 0.00000000000000000000001596 102.0
REGS1_k127_7797198_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 543.0
REGS1_k127_7797198_3 LRV protein FeS4 cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 421.0
REGS1_k127_7797198_4 TOBE domain K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 411.0
REGS1_k127_7797198_5 AAA domain, putative AbiEii toxin, Type IV TA system K06926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 382.0
REGS1_k127_7797198_6 Protein of unknown function, DUF269 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005013 258.0
REGS1_k127_7797198_7 Dinitrogenase iron-molybdenum cofactor K02596 - - 0.0000000000000000000000000000000000000000000000000000000000000000002322 237.0
REGS1_k127_7797198_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007599 229.0
REGS1_k127_7797198_9 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.0000000000000000000000000000000000000000000000000000003294 201.0
REGS1_k127_7844124_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1913.0
REGS1_k127_7844124_1 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 475.0
REGS1_k127_7844124_10 - - - - 0.0000001453 59.0
REGS1_k127_7844124_2 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 475.0
REGS1_k127_7844124_3 Specifically methylates the adenine in position 1618 of 23S rRNA K06970 - 2.1.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 415.0
REGS1_k127_7844124_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000001 234.0
REGS1_k127_7844124_6 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000001252 194.0
REGS1_k127_7844124_7 - - - - 0.000000000000000000000000000000000000000000000005449 175.0
REGS1_k127_7844124_8 addiction module killer protein - - - 0.00000000000000000000000000000000000000000001022 164.0
REGS1_k127_7844124_9 addiction module antidote protein - - - 0.00000000000000000000000000000000000000000001514 163.0
REGS1_k127_7878473_0 Carbohydrate phosphorylase - - - 6.75e-274 851.0
REGS1_k127_7878473_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 1.238e-219 689.0
REGS1_k127_7878473_2 Copper binding periplasmic protein CusF - - - 0.000000000000000000000000000000004443 131.0
REGS1_k127_7878473_3 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 0.000000007043 57.0
REGS1_k127_7889707_0 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase - - - 0.0 1289.0
REGS1_k127_7889707_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 604.0
REGS1_k127_7889707_2 cheY-homologous receiver domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 416.0
REGS1_k127_7889707_3 SMART HTH transcriptional regulator, Crp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 392.0
REGS1_k127_7889707_4 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 347.0
REGS1_k127_7889707_5 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 295.0
REGS1_k127_7889707_6 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000224 134.0
REGS1_k127_7889707_7 CsbD-like - - - 0.000000000000000683 81.0
REGS1_k127_7889707_8 Diguanylate cyclase - - - 0.000025 48.0
REGS1_k127_7929736_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 1.665e-250 777.0
REGS1_k127_7929736_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 504.0
REGS1_k127_7929736_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 469.0
REGS1_k127_7929736_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004218 262.0
REGS1_k127_7929736_4 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000005793 225.0
REGS1_k127_7929736_5 VanZ like family - - - 0.00000000000000000000000000000000000000000000000001986 181.0
REGS1_k127_7929736_6 - - - - 0.00000000000000000000000000000000000000004888 153.0
REGS1_k127_7988706_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 498.0
REGS1_k127_7988706_1 Ferritin-like domain K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 288.0
REGS1_k127_7988706_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000002502 117.0
REGS1_k127_7988706_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000007995 106.0
REGS1_k127_8094966_0 type I site-specific deoxyribonuclease activity K01153 - 3.1.21.3 0.0 1349.0
REGS1_k127_8094966_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1077.0
REGS1_k127_8094966_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 8.033e-254 788.0
REGS1_k127_8094966_3 PFAM KilA, N-terminal APSES-type HTH, DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 411.0
REGS1_k127_8094966_4 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000000000000004471 206.0
REGS1_k127_8094966_5 Dodecin K09165 - - 0.00000000000000000000000000000006709 125.0
REGS1_k127_8109976_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5e-324 1004.0
REGS1_k127_8109976_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 3.113e-201 631.0
REGS1_k127_8109976_10 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000004306 151.0
REGS1_k127_8109976_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 540.0
REGS1_k127_8109976_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 443.0
REGS1_k127_8109976_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 379.0
REGS1_k127_8109976_5 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 374.0
REGS1_k127_8109976_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 357.0
REGS1_k127_8109976_7 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 320.0
REGS1_k127_8109976_8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000009174 191.0
REGS1_k127_8109976_9 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000000000000000002482 155.0
REGS1_k127_8136163_0 Domain of unknown function (DUF3400) - - - 0.0 1070.0
REGS1_k127_8136163_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 9.066e-290 898.0
REGS1_k127_8136163_10 S-layer homology domain - - - 0.00006674 53.0
REGS1_k127_8136163_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 7.819e-246 766.0
REGS1_k127_8136163_3 - - - - 3.857e-202 642.0
REGS1_k127_8136163_4 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 3.622e-198 625.0
REGS1_k127_8136163_5 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 430.0
REGS1_k127_8136163_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 383.0
REGS1_k127_8136163_7 receptor K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 381.0
REGS1_k127_8136163_8 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004714 263.0
REGS1_k127_8136163_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003135 252.0
REGS1_k127_8164609_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1439.0
REGS1_k127_8164609_1 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 6.479e-197 618.0
REGS1_k127_8164609_2 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 498.0
REGS1_k127_8164609_3 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 497.0
REGS1_k127_8164609_4 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 316.0
REGS1_k127_8164609_5 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004661 277.0
REGS1_k127_8164609_6 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005008 253.0
REGS1_k127_8164609_7 Bacterial Ig-like domain 2 - - - 0.0000000000004144 78.0
REGS1_k127_8164609_8 NAD(P)H-binding - - - 0.000000000005658 66.0
REGS1_k127_8173910_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 582.0
REGS1_k127_8173910_1 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 568.0
REGS1_k127_8173910_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 514.0
REGS1_k127_8173910_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 477.0
REGS1_k127_8173910_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 362.0
REGS1_k127_8173910_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000000006723 184.0
REGS1_k127_8173910_6 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000002719 153.0
REGS1_k127_8173910_7 - - - - 0.00000000000000001173 88.0
REGS1_k127_8200229_0 SbmA/BacA-like family K02471 - - 2.189e-266 830.0
REGS1_k127_8200229_1 Collagenase K08303 - - 1.171e-265 822.0
REGS1_k127_8200229_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 524.0
REGS1_k127_8200229_3 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001853 266.0
REGS1_k127_8200229_4 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.00000000004359 64.0
REGS1_k127_8201852_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 598.0
REGS1_k127_8201852_1 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 521.0
REGS1_k127_8201852_2 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 436.0
REGS1_k127_8201852_3 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000001919 223.0
REGS1_k127_8250572_0 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 1.426e-307 949.0
REGS1_k127_8250572_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 6.416e-263 817.0
REGS1_k127_8250572_10 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 323.0
REGS1_k127_8250572_11 PFAM Uncharacterised conserved protein UCP030820 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
REGS1_k127_8250572_12 Protein of unknown function (DUF3579) - - - 0.0000000000000000000000000000000000000000000000000000000000003104 213.0
REGS1_k127_8250572_14 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000001605 137.0
REGS1_k127_8250572_15 Protein of unknown function (DUF3579) - - - 0.0000000000000000000000000002769 118.0
REGS1_k127_8250572_16 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000003319 89.0
REGS1_k127_8250572_2 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 4.642e-235 731.0
REGS1_k127_8250572_3 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 581.0
REGS1_k127_8250572_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 530.0
REGS1_k127_8250572_5 LysR substrate binding domain K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 490.0
REGS1_k127_8250572_6 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 449.0
REGS1_k127_8250572_7 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 419.0
REGS1_k127_8250572_8 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 400.0
REGS1_k127_8250572_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 333.0
REGS1_k127_8252192_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 449.0
REGS1_k127_8252192_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 383.0
REGS1_k127_8252192_2 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 302.0
REGS1_k127_8252192_3 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004412 271.0
REGS1_k127_8252192_4 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007276 267.0
REGS1_k127_8252192_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000009089 219.0
REGS1_k127_8252192_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000001408 90.0
REGS1_k127_8374527_0 PFAM TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 551.0
REGS1_k127_8374527_1 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000002104 193.0
REGS1_k127_8391645_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.779e-259 801.0
REGS1_k127_8391645_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 543.0
REGS1_k127_8391645_2 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 346.0
REGS1_k127_8391645_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 286.0
REGS1_k127_8393411_0 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 348.0
REGS1_k127_8393411_1 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 294.0
REGS1_k127_8393411_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 279.0
REGS1_k127_8393411_3 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000677 237.0
REGS1_k127_8393411_4 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000006442 185.0
REGS1_k127_8416201_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0 1066.0
REGS1_k127_8416201_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 9.792e-313 959.0
REGS1_k127_8416201_10 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000001966 58.0
REGS1_k127_8416201_2 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 3.286e-271 837.0
REGS1_k127_8416201_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K03737 - 1.2.7.1 1.021e-238 741.0
REGS1_k127_8416201_4 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 489.0
REGS1_k127_8416201_5 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 370.0
REGS1_k127_8416201_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001826 261.0
REGS1_k127_8416201_7 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000000000000000000000003487 214.0
REGS1_k127_8416201_8 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000000000000000000000002062 129.0
REGS1_k127_8454170_0 Nif-specific regulatory protein K02584 - - 1.101e-307 945.0
REGS1_k127_8454170_1 PAS PAC sensor signal transduction histidine kinase K05962 - 2.7.13.1 2.686e-273 850.0
REGS1_k127_8454170_2 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 295.0
REGS1_k127_8454170_3 Nif11 domain - - - 0.000000000000000000000000000000004042 130.0
REGS1_k127_8460934_0 PFAM DEAD DEAH box helicase domain protein K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 6.934e-257 799.0
REGS1_k127_8460934_1 PFAM RIO-like kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 470.0
REGS1_k127_8460934_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 338.0
REGS1_k127_8460934_3 WLM domain K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 280.0
REGS1_k127_8460934_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000001093 151.0
REGS1_k127_8460934_5 DNA-binding protein VF530 - - - 0.0000000000000000000000000000001298 124.0
REGS1_k127_8464807_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 3.049e-233 726.0
REGS1_k127_8464807_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000004921 239.0
REGS1_k127_8464807_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000007299 136.0
REGS1_k127_8467240_0 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 7.043e-318 975.0
REGS1_k127_8467240_1 PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 4.034e-261 807.0
REGS1_k127_8467240_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 6.195e-205 638.0
REGS1_k127_8467240_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 587.0
REGS1_k127_8467240_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 309.0
REGS1_k127_8467240_5 Bacterial regulatory protein, Fis family K03557 - - 0.0000000000000000000000000000000000000000009954 156.0
REGS1_k127_8467240_6 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000001481 60.0
REGS1_k127_8467240_7 Prokaryotic N-terminal methylation motif K02650 - - 0.0003164 47.0
REGS1_k127_8476720_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1220.0
REGS1_k127_8476720_1 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 358.0
REGS1_k127_8476720_10 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000003437 141.0
REGS1_k127_8476720_11 Domain of unknown function (DUF4902) - - - 0.0000000000000000000000000003641 118.0
REGS1_k127_8476720_12 HNH endonuclease - - - 0.000000000008764 70.0
REGS1_k127_8476720_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 359.0
REGS1_k127_8476720_3 Autoinducer binding domain K07782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 288.0
REGS1_k127_8476720_4 synthase K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007979 286.0
REGS1_k127_8476720_5 Acyl-homoserine-lactone synthase K13060,K13061 - 2.3.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000002467 258.0
REGS1_k127_8476720_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009456 239.0
REGS1_k127_8476720_7 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000001241 214.0
REGS1_k127_8476720_8 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000003916 203.0
REGS1_k127_8476720_9 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000001157 172.0
REGS1_k127_8521538_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 574.0
REGS1_k127_8521538_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 552.0
REGS1_k127_8521538_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001924 254.0
REGS1_k127_8521538_3 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000000000000174 157.0
REGS1_k127_8536234_0 Thiolase, C-terminal domain K00632 - 2.3.1.16 2.379e-220 685.0
REGS1_k127_8536234_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 501.0
REGS1_k127_8536234_2 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000006237 190.0
REGS1_k127_8536234_3 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000216 176.0
REGS1_k127_8553319_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 574.0
REGS1_k127_8553319_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 290.0
REGS1_k127_8553319_2 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000007557 204.0
REGS1_k127_8553319_3 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000000000000224 188.0
REGS1_k127_8570078_0 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 606.0
REGS1_k127_8570078_1 Belongs to the K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 472.0
REGS1_k127_8570078_2 Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 432.0
REGS1_k127_8570078_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001151 210.0
REGS1_k127_8570078_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000000000008598 166.0
REGS1_k127_8570078_5 Transcriptional regulator - - - 0.000000000000000000000000000000000001139 139.0
REGS1_k127_8574290_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 595.0
REGS1_k127_8574290_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 548.0
REGS1_k127_8574290_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 372.0
REGS1_k127_8574290_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 310.0
REGS1_k127_8574290_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000393 180.0
REGS1_k127_8574290_5 Autotransporter beta-domain - - - 0.00000000000000000000002806 108.0
REGS1_k127_8574290_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000001902 98.0
REGS1_k127_8574290_7 - - - - 0.000000000837 64.0
REGS1_k127_8626507_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 376.0
REGS1_k127_8626507_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 340.0
REGS1_k127_8626507_2 YGGT family K02221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000963 278.0
REGS1_k127_8626507_3 PFAM type II secretion system protein E K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000006379 204.0
REGS1_k127_8626507_4 - - - - 0.000001963 51.0
REGS1_k127_8652528_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 1.233e-286 883.0
REGS1_k127_8652528_1 PFAM NADH dehydrogenase (ubiquinone) 30 kDa subunit - - - 4.691e-277 858.0
REGS1_k127_8652528_2 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 341.0
REGS1_k127_8652528_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 320.0
REGS1_k127_8652528_4 Double sensory domain of two-component sensor kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 322.0
REGS1_k127_8652528_5 PFAM Spermine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 301.0
REGS1_k127_8652528_6 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 291.0
REGS1_k127_8652528_7 oxidoreductase K06940 - - 0.00000000000000000000000000000000000000000000000002861 186.0
REGS1_k127_8652528_8 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000006295 121.0
REGS1_k127_8666148_0 Soluble lytic murein transglycosylase L domain K08309 - - 1.686e-268 840.0
REGS1_k127_8666148_1 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 2.455e-241 748.0
REGS1_k127_8666148_10 TIGRFAM diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.65 0.00000008698 55.0
REGS1_k127_8666148_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 7.808e-204 638.0
REGS1_k127_8666148_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 2.711e-200 629.0
REGS1_k127_8666148_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 542.0
REGS1_k127_8666148_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 425.0
REGS1_k127_8666148_6 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 393.0
REGS1_k127_8666148_7 Domain of unknown function (DUF386) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001925 276.0
REGS1_k127_8666148_8 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000001676 230.0
REGS1_k127_8666148_9 - - - - 0.0000000000000000000000000000000000000003423 166.0
REGS1_k127_874561_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1127.0
REGS1_k127_874561_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 377.0
REGS1_k127_874561_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000001648 213.0
REGS1_k127_874561_3 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000000000000000001347 177.0
REGS1_k127_874561_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000006992 162.0
REGS1_k127_8806162_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.34e-306 953.0
REGS1_k127_8806162_1 serine threonine protein kinase K12132 - 2.7.11.1 3.179e-199 628.0
REGS1_k127_8806162_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000001699 223.0
REGS1_k127_8806162_3 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000001956 219.0
REGS1_k127_8916109_0 Alpha amylase, catalytic domain K01176 - 3.2.1.1 2.476e-268 835.0
REGS1_k127_8916109_1 Bacterial extracellular solute-binding protein K10108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 578.0
REGS1_k127_8916109_2 Maltose transport system permease protein MalF P2 domain K10109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 585.0
REGS1_k127_8916109_3 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01200 - 3.2.1.1,3.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 584.0
REGS1_k127_8916109_4 TOBE domain K10111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 464.0
REGS1_k127_8916109_5 Binding-protein-dependent transport system inner membrane component K10110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 448.0
REGS1_k127_8916109_6 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
REGS1_k127_8916109_7 Bacterial pullanase-associated domain - - - 0.000000000000000000000000000000001814 134.0
REGS1_k127_8916109_8 - - - - 0.000000000000000000005792 102.0
REGS1_k127_8916109_9 LamB porin - - - 0.0000000000000000634 82.0
REGS1_k127_8918452_0 PFAM glycosyl transferase family 39 - - - 3.968e-255 793.0
REGS1_k127_8918452_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 1.766e-245 770.0
REGS1_k127_8918452_2 PFAM major facilitator superfamily MFS_1 - - - 8.458e-226 704.0
REGS1_k127_8918452_3 PFAM sigma-54 factor interaction domain-containing protein K02667 - - 4.623e-219 686.0
REGS1_k127_8918452_4 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 566.0
REGS1_k127_8918452_5 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 578.0
REGS1_k127_8918452_6 - - - - 0.00000000000000000000000000000005091 136.0
REGS1_k127_8918452_7 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000009869 113.0
REGS1_k127_8918452_8 - K06950 - - 0.00000000000000000002421 93.0
REGS1_k127_8918452_9 - - - - 0.0001548 46.0
REGS1_k127_8927691_0 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 1.728e-210 659.0
REGS1_k127_8927691_1 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 1.201e-207 648.0
REGS1_k127_8927691_2 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 395.0
REGS1_k127_8927691_3 LamB porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003776 256.0
REGS1_k127_8940078_0 type iii restriction - - - 0.0 1407.0
REGS1_k127_8940078_1 FtsX-like permease family K02004 - - 0.0 1211.0
REGS1_k127_8940078_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 375.0
REGS1_k127_8940078_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000007801 105.0
REGS1_k127_9082143_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1170.0
REGS1_k127_9082143_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 574.0
REGS1_k127_9082143_10 translation initiation factor activity - - - 0.000000000000000000000004361 103.0
REGS1_k127_9082143_2 Anthranilate synthase component I domain protein K01665,K13950 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 544.0
REGS1_k127_9082143_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 424.0
REGS1_k127_9082143_4 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 419.0
REGS1_k127_9082143_5 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 413.0
REGS1_k127_9082143_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 347.0
REGS1_k127_9082143_7 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 338.0
REGS1_k127_9082143_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 317.0
REGS1_k127_9082143_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000004504 125.0
REGS1_k127_9094885_0 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 462.0
REGS1_k127_9094885_1 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 391.0
REGS1_k127_9094885_2 Domain of unknown function (DUF5062) - - - 0.00000000000000000000000000000001802 127.0
REGS1_k127_9095211_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 3.739e-269 832.0
REGS1_k127_9095211_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 588.0
REGS1_k127_9095211_2 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 404.0
REGS1_k127_9095211_3 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000001227 228.0
REGS1_k127_9095211_4 TIGRFAM succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000005531 203.0
REGS1_k127_9095211_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000000002534 134.0
REGS1_k127_9095211_6 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000003632 90.0
REGS1_k127_9095211_7 Radical SAM superfamily K04069 - 1.97.1.4 0.00000001402 57.0
REGS1_k127_9095211_8 chemotaxis, protein K03776 - - 0.0003889 48.0