Overview

ID MAG03311
Name REGS1_bin.47
Sample SMP0079
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Gallionellaceae
Genus DATDDB01
Species
Assembly information
Completeness (%) 94.77
Contamination (%) 0.37
GC content (%) 58.0
N50 (bp) 19,080
Genome size (bp) 2,400,004

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2247

Gene name Description KEGG GOs EC E-value Score Sequence
REGS1_k127_1083974_0 Putative diguanylate phosphodiesterase - - - 2.409e-276 876.0
REGS1_k127_1083974_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 520.0
REGS1_k127_1083974_2 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 447.0
REGS1_k127_1083974_3 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 347.0
REGS1_k127_1083974_4 TIGRFAM PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001759 262.0
REGS1_k127_1083974_5 Protein of unknown function (DUF3124) - - - 0.0000000000000000000000000000000000000000000000000000001192 199.0
REGS1_k127_1083974_6 Domain of unknown function (DUF4124) - - - 0.000000000000000008162 90.0
REGS1_k127_1147143_0 general secretion pathway protein D K02453 - - 2.802e-237 752.0
REGS1_k127_1147143_1 type II secretion system protein E K02454,K02652,K12276 - - 1.436e-226 713.0
REGS1_k127_1147143_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 507.0
REGS1_k127_1147143_3 PFAM Type II secretion system F domain K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 438.0
REGS1_k127_1147143_4 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 319.0
REGS1_k127_1147143_5 - - - - 0.000000000004917 72.0
REGS1_k127_1150316_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 597.0
REGS1_k127_1150316_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 511.0
REGS1_k127_1150316_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 357.0
REGS1_k127_1150316_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 287.0
REGS1_k127_1171125_0 Alpha-2-Macroglobulin K06894 - - 0.0 2029.0
REGS1_k127_1171125_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 7.362e-266 838.0
REGS1_k127_1171125_2 PFAM glycine cleavage T protein (aminomethyl transferase) K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 457.0
REGS1_k127_1171125_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000001648 228.0
REGS1_k127_1184195_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1926.0
REGS1_k127_1184195_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.026e-307 953.0
REGS1_k127_1184195_10 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 526.0
REGS1_k127_1184195_11 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 426.0
REGS1_k127_1184195_12 KR domain K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 386.0
REGS1_k127_1184195_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 385.0
REGS1_k127_1184195_14 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 382.0
REGS1_k127_1184195_15 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 362.0
REGS1_k127_1184195_16 metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 371.0
REGS1_k127_1184195_17 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 347.0
REGS1_k127_1184195_18 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 314.0
REGS1_k127_1184195_19 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 313.0
REGS1_k127_1184195_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.204e-222 695.0
REGS1_k127_1184195_20 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 288.0
REGS1_k127_1184195_21 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003834 278.0
REGS1_k127_1184195_22 response regulator K02485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001335 265.0
REGS1_k127_1184195_23 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000619 263.0
REGS1_k127_1184195_24 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004976 240.0
REGS1_k127_1184195_25 Belongs to the peptidase S11 family K01286,K07258,K07262 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000005182 243.0
REGS1_k127_1184195_26 cyclic nucleotide binding K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000006853 243.0
REGS1_k127_1184195_27 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000004899 192.0
REGS1_k127_1184195_28 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000006812 165.0
REGS1_k127_1184195_29 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000002075 155.0
REGS1_k127_1184195_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 5.494e-218 682.0
REGS1_k127_1184195_30 CRS1_YhbY K07574 - - 0.00000000000000000000000000000000532 130.0
REGS1_k127_1184195_31 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000000000006774 112.0
REGS1_k127_1184195_32 PFAM cytochrome c class I K08738 - - 0.0000000000000002251 84.0
REGS1_k127_1184195_34 Lysozyme inhibitor LprI - - - 0.0000000000000004969 84.0
REGS1_k127_1184195_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.101e-215 674.0
REGS1_k127_1184195_5 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 600.0
REGS1_k127_1184195_6 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 572.0
REGS1_k127_1184195_7 metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 562.0
REGS1_k127_1184195_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 517.0
REGS1_k127_1184195_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 493.0
REGS1_k127_1262515_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 541.0
REGS1_k127_1262515_1 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 290.0
REGS1_k127_1262515_2 Bacterial regulatory protein, Fis family K15012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 282.0
REGS1_k127_1262515_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000000000000000001176 222.0
REGS1_k127_1262515_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000002126 180.0
REGS1_k127_1288007_0 CHASE2 K01768 - 4.6.1.1 4.547e-282 884.0
REGS1_k127_1288007_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.522e-241 749.0
REGS1_k127_1288007_10 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 568.0
REGS1_k127_1288007_11 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 561.0
REGS1_k127_1288007_12 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 552.0
REGS1_k127_1288007_13 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 541.0
REGS1_k127_1288007_14 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 530.0
REGS1_k127_1288007_15 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 516.0
REGS1_k127_1288007_16 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 519.0
REGS1_k127_1288007_17 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 490.0
REGS1_k127_1288007_18 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 482.0
REGS1_k127_1288007_19 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 448.0
REGS1_k127_1288007_2 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 1.696e-223 694.0
REGS1_k127_1288007_20 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 441.0
REGS1_k127_1288007_21 RNA cap guanine-N2 methyltransferase K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 435.0
REGS1_k127_1288007_22 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 425.0
REGS1_k127_1288007_23 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 398.0
REGS1_k127_1288007_24 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 396.0
REGS1_k127_1288007_25 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 380.0
REGS1_k127_1288007_26 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 358.0
REGS1_k127_1288007_27 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 352.0
REGS1_k127_1288007_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 341.0
REGS1_k127_1288007_29 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 334.0
REGS1_k127_1288007_3 PFAM aminotransferase class I and II K14267 - 2.6.1.17 2.734e-211 661.0
REGS1_k127_1288007_30 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 308.0
REGS1_k127_1288007_31 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 289.0
REGS1_k127_1288007_32 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 293.0
REGS1_k127_1288007_33 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001272 292.0
REGS1_k127_1288007_34 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008385 263.0
REGS1_k127_1288007_35 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002972 238.0
REGS1_k127_1288007_36 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000009536 229.0
REGS1_k127_1288007_37 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000002216 190.0
REGS1_k127_1288007_38 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000005862 174.0
REGS1_k127_1288007_39 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000001231 164.0
REGS1_k127_1288007_4 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 6.666e-210 657.0
REGS1_k127_1288007_40 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000001224 154.0
REGS1_k127_1288007_41 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000002581 151.0
REGS1_k127_1288007_42 Amino acid permease - - - 0.0000000000000000000000000000000002903 133.0
REGS1_k127_1288007_43 Competence protein K02237 - - 0.000000000000000000000000000003195 126.0
REGS1_k127_1288007_44 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000001861 124.0
REGS1_k127_1288007_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.269e-207 653.0
REGS1_k127_1288007_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 5.668e-207 648.0
REGS1_k127_1288007_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.123e-198 623.0
REGS1_k127_1288007_8 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 599.0
REGS1_k127_1288007_9 Periplasmic sensor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 588.0
REGS1_k127_1306993_0 Belongs to the peptidase S16 family - - - 4.339e-287 903.0
REGS1_k127_1306993_1 Diguanylate cyclase - - - 2.112e-227 751.0
REGS1_k127_1306993_10 diguanylate cyclase K13069 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 304.0
REGS1_k127_1306993_11 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000666 267.0
REGS1_k127_1306993_12 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000002214 247.0
REGS1_k127_1306993_13 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000000001439 238.0
REGS1_k127_1306993_14 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000000000000188 205.0
REGS1_k127_1306993_15 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000006612 199.0
REGS1_k127_1306993_16 Smr domain - - - 0.00000000000000000000000000000000000000000000000000001121 196.0
REGS1_k127_1306993_17 NlpC/P60 family K19303 - - 0.0000000000000000000000000000000000000000000004908 170.0
REGS1_k127_1306993_18 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000004053 175.0
REGS1_k127_1306993_19 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000168 171.0
REGS1_k127_1306993_2 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 2.588e-200 633.0
REGS1_k127_1306993_20 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02019 - - 0.00000000000000000000000000000000008925 139.0
REGS1_k127_1306993_21 Tetratricopeptide repeat - - - 0.000000000000000000005938 102.0
REGS1_k127_1306993_22 - - - - 0.00000000000002741 79.0
REGS1_k127_1306993_23 ABC transporter - - - 0.00000001193 65.0
REGS1_k127_1306993_26 Bacterial extracellular solute-binding protein K02020 - - 0.00001708 52.0
REGS1_k127_1306993_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 583.0
REGS1_k127_1306993_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 565.0
REGS1_k127_1306993_5 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 532.0
REGS1_k127_1306993_6 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 381.0
REGS1_k127_1306993_7 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 376.0
REGS1_k127_1306993_8 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
REGS1_k127_1306993_9 ATP-binding protein K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 319.0
REGS1_k127_1319177_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 543.0
REGS1_k127_1319177_1 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 309.0
REGS1_k127_1319177_2 NAD+ binding K12410 - - 0.00000000000000000000000000000000000000000000000004207 187.0
REGS1_k127_1319177_3 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000007342 67.0
REGS1_k127_1319177_4 - - - - 0.00000001038 62.0
REGS1_k127_1341329_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 503.0
REGS1_k127_1341329_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 447.0
REGS1_k127_1341329_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 384.0
REGS1_k127_1341329_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 370.0
REGS1_k127_1341329_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 345.0
REGS1_k127_1341329_5 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 326.0
REGS1_k127_1341329_6 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 325.0
REGS1_k127_1341329_7 - - - - 0.00000000000000000000000000000000000000000000000000008547 191.0
REGS1_k127_1341329_8 Domain of unknown function (DUF4375) - - - 0.000000003651 59.0
REGS1_k127_1428480_0 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000491 236.0
REGS1_k127_1428480_1 - - - - 0.0000000000000000000000000000000000000000000000000000003892 202.0
REGS1_k127_1428480_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000005052 204.0
REGS1_k127_1428480_3 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000002186 123.0
REGS1_k127_1428480_4 - - - - 0.000000000000000245 82.0
REGS1_k127_1451890_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1602.0
REGS1_k127_1451890_1 Threonine synthase N terminus K01733 - 4.2.3.1 4.154e-276 852.0
REGS1_k127_1451890_10 Cupin 2, conserved barrel domain protein - - - 0.00000000003235 68.0
REGS1_k127_1451890_2 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 6.887e-251 776.0
REGS1_k127_1451890_3 Homoserine dehydrogenase K00003 - 1.1.1.3 3.021e-242 752.0
REGS1_k127_1451890_4 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 520.0
REGS1_k127_1451890_5 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 472.0
REGS1_k127_1451890_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 399.0
REGS1_k127_1451890_7 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 327.0
REGS1_k127_1451890_8 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000003789 176.0
REGS1_k127_1451890_9 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000001005 148.0
REGS1_k127_1619370_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 4.384e-199 624.0
REGS1_k127_1619370_1 Pfam Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 596.0
REGS1_k127_1619370_10 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 - 2.1.1.182,2.1.1.184 0.0000000000000000000000000000000000000000000000000000000000000008045 227.0
REGS1_k127_1619370_11 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000001439 220.0
REGS1_k127_1619370_12 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000003915 154.0
REGS1_k127_1619370_13 - - - - 0.000000000000000000000000000000002389 138.0
REGS1_k127_1619370_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000002855 96.0
REGS1_k127_1619370_15 RmlD substrate binding domain K00067 - 1.1.1.133 0.00000000006293 64.0
REGS1_k127_1619370_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 546.0
REGS1_k127_1619370_3 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 519.0
REGS1_k127_1619370_4 beta-fructofuranosidase activity K01193 - 3.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 456.0
REGS1_k127_1619370_5 reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 437.0
REGS1_k127_1619370_6 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 410.0
REGS1_k127_1619370_7 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 404.0
REGS1_k127_1619370_8 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 322.0
REGS1_k127_1619370_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 263.0
REGS1_k127_1623888_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1392.0
REGS1_k127_1623888_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000007161 214.0
REGS1_k127_1623888_2 bacterial (prokaryotic) histone like domain - - - 0.0000000000000000000000000000000000000003478 151.0
REGS1_k127_1623888_3 - - - - 0.00000000000000001406 84.0
REGS1_k127_1623888_4 DNA integration - - - 0.0000000001101 72.0
REGS1_k127_1656034_0 receptor K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 436.0
REGS1_k127_1656034_1 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 287.0
REGS1_k127_1656034_2 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000002592 203.0
REGS1_k127_1656034_3 Cell division protein ZapA K09888 - - 0.000000000000000000000000000000000000000000000003174 174.0
REGS1_k127_1656034_4 - - - - 0.00000000000002488 74.0
REGS1_k127_172970_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1195.0
REGS1_k127_172970_1 Polysulphide reductase, NrfD K00185 - - 1.13e-288 888.0
REGS1_k127_172970_10 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 398.0
REGS1_k127_172970_11 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 378.0
REGS1_k127_172970_12 Glutathione S-transferase, C-terminal domain K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 362.0
REGS1_k127_172970_13 Belongs to the GbsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 357.0
REGS1_k127_172970_14 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 340.0
REGS1_k127_172970_15 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 327.0
REGS1_k127_172970_16 Membrane-associated sensor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 324.0
REGS1_k127_172970_17 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 303.0
REGS1_k127_172970_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
REGS1_k127_172970_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001957 279.0
REGS1_k127_172970_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.007e-259 806.0
REGS1_k127_172970_20 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009151 285.0
REGS1_k127_172970_21 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004281 274.0
REGS1_k127_172970_22 membrane K08973 - - 0.00000000000000000000000000000000000000000000000000006434 192.0
REGS1_k127_172970_23 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000005194 166.0
REGS1_k127_172970_24 - - - - 0.00000000000000000000000000000000000000001086 158.0
REGS1_k127_172970_25 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000167 154.0
REGS1_k127_172970_26 YGGT family K02221 - - 0.0000000000000000000000000000000000000248 152.0
REGS1_k127_172970_27 DUF167 K09131 - - 0.00000000000000000000000000000000005356 140.0
REGS1_k127_172970_28 Thioesterase-like superfamily - - - 0.0000000000000000000001539 98.0
REGS1_k127_172970_29 - - - - 0.0000000000000001509 80.0
REGS1_k127_172970_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.233e-219 688.0
REGS1_k127_172970_4 PFAM type II secretion system protein E K02670 - - 1.654e-215 674.0
REGS1_k127_172970_5 PFAM type II secretion system protein E K02669,K12203 - - 5.478e-205 641.0
REGS1_k127_172970_6 THUMP K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 587.0
REGS1_k127_172970_7 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 554.0
REGS1_k127_172970_8 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 538.0
REGS1_k127_172970_9 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 425.0
REGS1_k127_1773372_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 4.944e-255 791.0
REGS1_k127_1773372_1 Nitrogenase component 1 type Oxidoreductase K02592 - - 1.268e-197 628.0
REGS1_k127_1773372_2 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) K05951 - 2.4.2.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 329.0
REGS1_k127_1773372_3 Dinitrogenase iron-molybdenum cofactor K02596 - - 0.0000000000000000000000000000000000000000000000000000000000000003226 224.0
REGS1_k127_1773372_4 Protein of unknown function, DUF269 - - - 0.0000000000004809 71.0
REGS1_k127_1819999_0 PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 4.689e-247 766.0
REGS1_k127_1819999_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 2.79e-203 638.0
REGS1_k127_1819999_2 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 9.851e-198 618.0
REGS1_k127_1819999_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001864 269.0
REGS1_k127_1819999_4 Chemoreceptor zinc-binding domain - - - 0.000000000000000000001385 100.0
REGS1_k127_1863163_0 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 561.0
REGS1_k127_1863163_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001827 230.0
REGS1_k127_1863163_10 Putative diguanylate phosphodiesterase - - - 0.00000000000104 70.0
REGS1_k127_1863163_11 OmpA-like transmembrane domain K03286 - - 0.00002441 53.0
REGS1_k127_1863163_2 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000002338 222.0
REGS1_k127_1863163_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000006468 210.0
REGS1_k127_1863163_4 Rhomboid family K02441 - - 0.0000000000000000000000000000000000000000001903 168.0
REGS1_k127_1863163_5 Haemolytic - - - 0.00000000000000000000000000000000001745 139.0
REGS1_k127_1863163_6 - - - - 0.00000000000000000000000000000008818 129.0
REGS1_k127_1863163_7 carboxylic acid catabolic process K01736 - 4.2.3.5 0.0000000000000000000000000001493 121.0
REGS1_k127_1863163_8 Polyribonucleotide nucleotidyltransferase - - - 0.0000000000000000000001566 109.0
REGS1_k127_1893872_0 von Willebrand factor, type A - - - 2.906e-299 935.0
REGS1_k127_1893872_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 7.835e-295 906.0
REGS1_k127_1893872_10 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 325.0
REGS1_k127_1893872_11 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 315.0
REGS1_k127_1893872_12 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 293.0
REGS1_k127_1893872_13 undecaprenyl-phosphate glucose phosphotransferase activity K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000007215 229.0
REGS1_k127_1893872_14 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000397 197.0
REGS1_k127_1893872_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000006571 183.0
REGS1_k127_1893872_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000001508 153.0
REGS1_k127_1893872_17 membrane - - - 0.00000000000000000000000000000000005323 137.0
REGS1_k127_1893872_18 Cold shock protein domain K03704 - - 0.00000000000000000000000000000001449 139.0
REGS1_k127_1893872_19 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000007601 104.0
REGS1_k127_1893872_2 Polysaccharide biosynthesis protein - - - 4.818e-245 771.0
REGS1_k127_1893872_3 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 492.0
REGS1_k127_1893872_4 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 482.0
REGS1_k127_1893872_5 Glycosyltransferase Family 4 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 472.0
REGS1_k127_1893872_6 ATPase associated with various cellular activities AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 460.0
REGS1_k127_1893872_7 GDP-mannose 4,6 dehydratase K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 461.0
REGS1_k127_1893872_8 LysR substrate binding domain K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 456.0
REGS1_k127_1893872_9 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 409.0
REGS1_k127_201891_0 Transport of potassium into the cell K03549 - - 0.0 1023.0
REGS1_k127_201891_1 Integral membrane sensor signal transduction histidine kinase K07646 - 2.7.13.3 1.065e-273 847.0
REGS1_k127_201891_2 Transport of potassium into the cell K03549 - - 1.368e-261 820.0
REGS1_k127_201891_3 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007868 278.0
REGS1_k127_201891_4 - - - - 0.000000001806 60.0
REGS1_k127_2036184_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 409.0
REGS1_k127_2036184_1 mechanosensitive - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 346.0
REGS1_k127_2036184_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 329.0
REGS1_k127_2075213_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1498.0
REGS1_k127_2075213_1 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 1.841e-262 857.0
REGS1_k127_2075213_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 349.0
REGS1_k127_2075213_11 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 303.0
REGS1_k127_2075213_12 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 291.0
REGS1_k127_2075213_2 Putative diguanylate phosphodiesterase - - - 8.887e-194 629.0
REGS1_k127_2075213_3 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 572.0
REGS1_k127_2075213_4 Urea ABC transporter, urea binding protein K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 522.0
REGS1_k127_2075213_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 503.0
REGS1_k127_2075213_6 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 502.0
REGS1_k127_2075213_7 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 456.0
REGS1_k127_2075213_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 424.0
REGS1_k127_2075213_9 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 422.0
REGS1_k127_2090021_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.652e-234 732.0
REGS1_k127_2090021_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.655e-234 732.0
REGS1_k127_2090021_10 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000002399 206.0
REGS1_k127_2090021_11 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.00000000000000000000000000000000000000000000000000000001592 198.0
REGS1_k127_2090021_12 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000007883 143.0
REGS1_k127_2090021_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 454.0
REGS1_k127_2090021_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 449.0
REGS1_k127_2090021_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 425.0
REGS1_k127_2090021_5 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 396.0
REGS1_k127_2090021_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 358.0
REGS1_k127_2090021_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 360.0
REGS1_k127_2090021_8 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000496 235.0
REGS1_k127_2090021_9 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000005706 219.0
REGS1_k127_2190750_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.102e-289 892.0
REGS1_k127_2190750_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.289e-268 832.0
REGS1_k127_2190750_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 2.561e-204 640.0
REGS1_k127_2190750_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 591.0
REGS1_k127_2190750_4 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 334.0
REGS1_k127_2190750_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000007694 140.0
REGS1_k127_2219153_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 601.0
REGS1_k127_2219153_1 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 481.0
REGS1_k127_2219153_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 417.0
REGS1_k127_2219153_3 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 411.0
REGS1_k127_2219153_4 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 386.0
REGS1_k127_2219153_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 327.0
REGS1_k127_2219153_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000007325 252.0
REGS1_k127_2219153_7 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000002826 213.0
REGS1_k127_2219153_8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000001121 141.0
REGS1_k127_2233311_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 1.44e-276 856.0
REGS1_k127_2233311_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.162e-269 841.0
REGS1_k127_2233311_2 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 583.0
REGS1_k127_2233311_3 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 380.0
REGS1_k127_2233311_4 PFAM Glycosyl transferase family 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 374.0
REGS1_k127_2233311_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 365.0
REGS1_k127_2233311_6 glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001117 272.0
REGS1_k127_2233311_7 - - - - 0.0000000000000000000000000000000000000000000002409 172.0
REGS1_k127_2233311_8 Caenorhabditis protein of unknown function, DUF268 - - - 0.0000000000000000000000000001024 117.0
REGS1_k127_23601_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365,K05366 - 2.4.1.129,3.4.16.4 0.0 1223.0
REGS1_k127_23601_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 482.0
REGS1_k127_23601_12 Domain of unknown function (DUF4389) - - - 0.000000000000000003832 87.0
REGS1_k127_23601_13 Chalcone isomerase-like - - - 0.000000000119 63.0
REGS1_k127_23601_2 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 409.0
REGS1_k127_23601_3 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 317.0
REGS1_k127_23601_4 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001194 248.0
REGS1_k127_23601_5 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000001492 222.0
REGS1_k127_23601_6 KTSC domain - - - 0.0000000000000000000000000000000000000000000097 166.0
REGS1_k127_23601_7 - - - - 0.0000000000000000000000000000000000000001008 160.0
REGS1_k127_23601_8 photosynthesis K12132,K20543 - 2.7.11.1 0.0000000000000000000000000000000000000007348 156.0
REGS1_k127_23601_9 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000002159 146.0
REGS1_k127_2363648_0 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 566.0
REGS1_k127_2363648_1 Sigma-54 interaction domain K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 479.0
REGS1_k127_2363648_2 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003196 272.0
REGS1_k127_2363648_3 - K06950 - - 0.0000000000000000000344 92.0
REGS1_k127_2431147_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1726.0
REGS1_k127_2431147_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 449.0
REGS1_k127_2431147_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 367.0
REGS1_k127_2431147_3 Sel1-like repeats. - - - 0.00000000000000000046 93.0
REGS1_k127_2441309_0 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 420.0
REGS1_k127_2441309_1 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) - - - 0.00000000000000000000000000000000000000000000000001774 188.0
REGS1_k127_2441309_2 polyketide cyclase - - - 0.00000000000000000000000000000000000003714 148.0
REGS1_k127_2448131_0 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 387.0
REGS1_k127_2448131_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 338.0
REGS1_k127_2448131_2 VirC1 protein K03496 - - 0.00000000000000000000000000000000000000000000006441 180.0
REGS1_k127_2495563_0 AAA domain - - - 1.787e-305 947.0
REGS1_k127_2495563_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.429e-218 680.0
REGS1_k127_2495563_10 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001095 256.0
REGS1_k127_2495563_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000001012 239.0
REGS1_k127_2495563_12 Domain of unknown function (DUF4297) - - - 0.00000000000000000000000000000000000000006399 151.0
REGS1_k127_2495563_13 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000006321 137.0
REGS1_k127_2495563_14 Protein of unknown function (DUF493) K09158 - - 0.0000000000000000000000000000000037 129.0
REGS1_k127_2495563_15 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000002587 123.0
REGS1_k127_2495563_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 576.0
REGS1_k127_2495563_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 499.0
REGS1_k127_2495563_4 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 480.0
REGS1_k127_2495563_5 PFAM aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 466.0
REGS1_k127_2495563_6 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 404.0
REGS1_k127_2495563_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 315.0
REGS1_k127_2495563_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 312.0
REGS1_k127_2495563_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 303.0
REGS1_k127_2603903_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1515.0
REGS1_k127_2603903_1 general secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 304.0
REGS1_k127_2603903_2 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002866 267.0
REGS1_k127_2603903_3 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000003944 208.0
REGS1_k127_2603903_4 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000000000000000000000000000001398 168.0
REGS1_k127_2603903_5 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000002369 156.0
REGS1_k127_2603903_6 General secretion pathway K02462 - - 0.000000000000000000000000000000007607 135.0
REGS1_k127_2603903_9 general secretion pathway protein K02457 - - 0.00000000001731 72.0
REGS1_k127_2607548_0 PhoQ Sensor - - - 6.867e-293 906.0
REGS1_k127_2607548_1 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 8.068e-211 660.0
REGS1_k127_2607548_2 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000000000007975 227.0
REGS1_k127_2665915_0 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 314.0
REGS1_k127_2665915_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007196 265.0
REGS1_k127_2665915_2 PFAM PEGA domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003961 267.0
REGS1_k127_2665915_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000007207 219.0
REGS1_k127_2665915_4 elongation factor Tu K02358 - - 0.0000000000000000005432 86.0
REGS1_k127_2713499_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1160.0
REGS1_k127_2713499_1 - - - - 0.0 1079.0
REGS1_k127_2713499_10 - - - - 0.000000000000000000000001173 107.0
REGS1_k127_2713499_2 ABC transporter transmembrane region K06147 - - 1.503e-277 867.0
REGS1_k127_2713499_3 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 508.0
REGS1_k127_2713499_4 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 432.0
REGS1_k127_2713499_5 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 318.0
REGS1_k127_2713499_6 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000004928 228.0
REGS1_k127_2713499_7 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000009973 150.0
REGS1_k127_2713499_8 SMART Cold shock protein K03704 - - 0.000000000000000000000000000000000003001 139.0
REGS1_k127_2713499_9 - - - - 0.00000000000000000000000000000001846 135.0
REGS1_k127_2739194_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1022.0
REGS1_k127_2739194_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 609.0
REGS1_k127_2739194_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 549.0
REGS1_k127_2739194_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 295.0
REGS1_k127_2739194_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000001587 171.0
REGS1_k127_274223_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1195.0
REGS1_k127_274223_1 Protein of unknown function - - - 0.0 1110.0
REGS1_k127_274223_10 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 308.0
REGS1_k127_274223_11 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008848 277.0
REGS1_k127_274223_12 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000004675 229.0
REGS1_k127_274223_13 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000000000000004211 222.0
REGS1_k127_274223_14 PFAM guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.00000000000000000000000000000000000000000001058 165.0
REGS1_k127_274223_15 Barstar (barnase inhibitor) - - - 0.000000000000000000000000000000000000000004279 158.0
REGS1_k127_274223_16 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000002506 129.0
REGS1_k127_274223_17 Putative regulatory protein - - - 0.0000000000000000000000000004899 114.0
REGS1_k127_274223_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1107.0
REGS1_k127_274223_3 modulator of DNA gyrase K03568 - - 2.578e-226 712.0
REGS1_k127_274223_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 1.124e-197 621.0
REGS1_k127_274223_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 481.0
REGS1_k127_274223_6 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 471.0
REGS1_k127_274223_7 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 402.0
REGS1_k127_274223_8 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 322.0
REGS1_k127_274223_9 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 318.0
REGS1_k127_2879006_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 445.0
REGS1_k127_2879006_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 377.0
REGS1_k127_2879006_2 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000007555 203.0
REGS1_k127_2879006_3 Protein of unknown function (DUF2846) - - - 0.0000000000000000000000000000000000000000000000000000001505 198.0
REGS1_k127_2879006_4 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000268 129.0
REGS1_k127_2879006_5 - - - - 0.0000000000000000000000000001302 119.0
REGS1_k127_2879006_6 Trm112p-like protein K09791 - - 0.00000000000000000000000001375 109.0
REGS1_k127_2879006_7 serine protease K07403 - - 0.00000000000000001044 85.0
REGS1_k127_2879006_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000001237 77.0
REGS1_k127_3007883_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.294e-240 749.0
REGS1_k127_3007883_1 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 518.0
REGS1_k127_3007883_10 - - - - 0.000000000000000000000000000000000000000000681 179.0
REGS1_k127_3007883_11 - - - - 0.0000000000000000000000000000000000005578 144.0
REGS1_k127_3007883_12 Cytochrome C assembly protein - - - 0.00000000000000000000000001647 112.0
REGS1_k127_3007883_13 - - - - 0.000000000000000000000001171 108.0
REGS1_k127_3007883_14 phage Tail Collar - - - 0.000000000000000000003502 109.0
REGS1_k127_3007883_15 peptidase - - - 0.00000000000000003211 95.0
REGS1_k127_3007883_16 Domain of unknown function (DUF4376) - - - 0.0000000000000001093 88.0
REGS1_k127_3007883_17 Phage tail-collar fibre protein - - - 0.0000000000001461 84.0
REGS1_k127_3007883_18 - - - - 0.0000000000002593 83.0
REGS1_k127_3007883_19 Phage virion morphogenesis - - - 0.00000000002089 68.0
REGS1_k127_3007883_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 440.0
REGS1_k127_3007883_20 chitinase - - - 0.00000000006686 76.0
REGS1_k127_3007883_21 Caudovirales tail fibre assembly protein, lambda gpK - - - 0.0000000008996 67.0
REGS1_k127_3007883_22 phage Tail Collar - - - 0.000000003087 70.0
REGS1_k127_3007883_3 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 422.0
REGS1_k127_3007883_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 438.0
REGS1_k127_3007883_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 387.0
REGS1_k127_3007883_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 400.0
REGS1_k127_3007883_7 tail collar domain protein - - - 0.000000000000000000000000000000000000000000000000000000009767 224.0
REGS1_k127_3007883_8 LysM domain - - - 0.0000000000000000000000000000000000000000000000000004012 197.0
REGS1_k127_3007883_9 Baseplate assembly protein - - - 0.00000000000000000000000000000000000000000000000001128 188.0
REGS1_k127_3132371_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1095.0
REGS1_k127_3132371_1 Belongs to the GPI family K01810 - 5.3.1.9 4.813e-253 794.0
REGS1_k127_3132371_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 5.021e-218 682.0
REGS1_k127_3132371_3 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 543.0
REGS1_k127_3132371_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 531.0
REGS1_k127_3132371_5 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002243 276.0
REGS1_k127_3132371_6 Protein of unknown function (DUF559) K03427 - 2.1.1.72 0.00000000000000000000000000000000006673 136.0
REGS1_k127_3132371_7 dUTPase - - - 0.000000000000001028 89.0
REGS1_k127_3174738_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1517.0
REGS1_k127_3174738_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1274.0
REGS1_k127_3174738_10 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 484.0
REGS1_k127_3174738_11 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 458.0
REGS1_k127_3174738_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 422.0
REGS1_k127_3174738_13 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 450.0
REGS1_k127_3174738_14 virion core protein (lumpy skin disease virus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
REGS1_k127_3174738_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 394.0
REGS1_k127_3174738_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 389.0
REGS1_k127_3174738_17 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 328.0
REGS1_k127_3174738_18 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 310.0
REGS1_k127_3174738_19 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007359 287.0
REGS1_k127_3174738_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1174.0
REGS1_k127_3174738_20 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001019 267.0
REGS1_k127_3174738_21 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006649 250.0
REGS1_k127_3174738_22 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000001227 228.0
REGS1_k127_3174738_23 Restriction endonuclease PvuII - - - 0.000000000000000000000000000000000000000000000000000000000000000215 224.0
REGS1_k127_3174738_24 Cytochrome C biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000001806 198.0
REGS1_k127_3174738_25 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000002669 160.0
REGS1_k127_3174738_26 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine - - - 0.000000000000000000000000000000000000004415 148.0
REGS1_k127_3174738_27 Helix-turn-helix domain - - - 0.0000000000000000003664 89.0
REGS1_k127_3174738_28 Domain of Unknown Function (DUF350) - - - 0.000000000000000007103 85.0
REGS1_k127_3174738_29 Belongs to the 'phage' integrase family - - - 0.0000000000000004524 85.0
REGS1_k127_3174738_3 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1016.0
REGS1_k127_3174738_30 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.0000000000003174 70.0
REGS1_k127_3174738_32 GKAP/Homer scaffold activity K15009 - - 0.0001808 48.0
REGS1_k127_3174738_4 PFAM aminotransferase class I and II K00812 - 2.6.1.1 4.187e-234 728.0
REGS1_k127_3174738_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.283e-221 701.0
REGS1_k127_3174738_6 SurA N-terminal domain K03770 - 5.2.1.8 1.271e-213 680.0
REGS1_k127_3174738_7 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 602.0
REGS1_k127_3174738_8 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 595.0
REGS1_k127_3174738_9 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 510.0
REGS1_k127_3196425_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.655e-278 860.0
REGS1_k127_3196425_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 2.458e-218 689.0
REGS1_k127_3196425_2 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 426.0
REGS1_k127_3196425_3 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007797 241.0
REGS1_k127_3196425_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000005325 226.0
REGS1_k127_3196425_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000000003638 219.0
REGS1_k127_3257826_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 2.628e-281 888.0
REGS1_k127_3257826_1 May be involved in recombinational repair of damaged DNA K03631 - - 1.563e-246 771.0
REGS1_k127_3257826_10 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 322.0
REGS1_k127_3257826_11 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000001678 187.0
REGS1_k127_3257826_12 Protein of unknown function (DUF2971) - - - 0.000000000000000000000000000004513 126.0
REGS1_k127_3257826_13 cytochrome - - - 0.0000000000000000000000000002499 118.0
REGS1_k127_3257826_2 Cytochrome c7 and related cytochrome c - - - 5.162e-218 698.0
REGS1_k127_3257826_3 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 580.0
REGS1_k127_3257826_4 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 566.0
REGS1_k127_3257826_5 Winged helix-turn-helix transcription repressor, HrcA DNA-binding K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 550.0
REGS1_k127_3257826_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 419.0
REGS1_k127_3257826_7 glycosyl - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 415.0
REGS1_k127_3257826_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 402.0
REGS1_k127_3257826_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 379.0
REGS1_k127_3343002_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 580.0
REGS1_k127_3343002_1 - - - - 0.000000000000000000000000000000000000000000000000000000000003974 211.0
REGS1_k127_3343002_2 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000001099 81.0
REGS1_k127_3343002_3 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.0003061 43.0
REGS1_k127_3382366_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.826e-208 653.0
REGS1_k127_3382366_1 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 502.0
REGS1_k127_3382366_2 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 368.0
REGS1_k127_3382366_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000004707 162.0
REGS1_k127_3382366_4 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000001351 77.0
REGS1_k127_3443143_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 493.0
REGS1_k127_3443143_1 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 389.0
REGS1_k127_3443143_11 Protein conserved in bacteria - - - 0.0000000000000000001033 98.0
REGS1_k127_3443143_12 - - - - 0.00000000000000002399 87.0
REGS1_k127_3443143_13 Glycosyltransferase like family 2 - - - 0.0000000708 60.0
REGS1_k127_3443143_14 D-alanyl-D-alanine carboxypeptidase - - - 0.0008502 49.0
REGS1_k127_3443143_2 Inner membrane protein CreD K06143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 383.0
REGS1_k127_3443143_3 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 288.0
REGS1_k127_3443143_4 Transcriptional regulatory protein, C terminal K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004778 278.0
REGS1_k127_3443143_5 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002441 244.0
REGS1_k127_3443143_6 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000000000000000000000000000000000002029 216.0
REGS1_k127_3443143_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000009262 182.0
REGS1_k127_3443143_8 - - - - 0.000000000000000000000000000000000000006697 148.0
REGS1_k127_3443143_9 DoxX-like family - - - 0.0000000000000000000000000000000000001197 145.0
REGS1_k127_3448010_0 FAD dependent oxidoreductase K00313 - - 1.222e-231 721.0
REGS1_k127_3448010_1 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 559.0
REGS1_k127_3448010_10 Ferredoxin III - - - 0.00000000000000000000002363 103.0
REGS1_k127_3448010_11 Rop-like - - - 0.0000000000000000003999 89.0
REGS1_k127_3448010_12 - - - - 0.000000000000000004235 89.0
REGS1_k127_3448010_2 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001695 282.0
REGS1_k127_3448010_3 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000363 214.0
REGS1_k127_3448010_4 - - - - 0.00000000000000000000000000000000000000000000000000000000003377 210.0
REGS1_k127_3448010_5 PFAM GCN5-related N-acetyltransferase K22441 - 2.3.1.57 0.00000000000000000000000000000000000000000000000000004623 190.0
REGS1_k127_3448010_6 Protein of unknown function, DUF269 - - - 0.0000000000000000000000000000000000000000000000000001524 186.0
REGS1_k127_3448010_7 Could be a 3Fe-4S cluster-containing protein K03855 - - 0.0000000000000000000000000000000000000000000000001897 177.0
REGS1_k127_3448010_8 Ferredoxin - - - 0.000000000000000000000000000000000000000000155 160.0
REGS1_k127_3448010_9 NifQ K15790 - - 0.0000000000000000000000000000000000000000003757 166.0
REGS1_k127_3532378_0 Domain of unknown function (DUF3400) - - - 0.0 2139.0
REGS1_k127_3532378_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1740.0
REGS1_k127_3532378_10 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000007942 117.0
REGS1_k127_3532378_2 4 iron, 4 sulfur cluster binding K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 534.0
REGS1_k127_3532378_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 521.0
REGS1_k127_3532378_4 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 521.0
REGS1_k127_3532378_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 392.0
REGS1_k127_3532378_6 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 372.0
REGS1_k127_3532378_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000002256 254.0
REGS1_k127_3532378_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000002259 211.0
REGS1_k127_3532378_9 Universal stress protein family - - - 0.000000000000000000000000000000000000000000001562 170.0
REGS1_k127_3537446_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1117.0
REGS1_k127_3537446_1 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 3.081e-301 939.0
REGS1_k127_3537446_10 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 4.739e-207 649.0
REGS1_k127_3537446_11 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 595.0
REGS1_k127_3537446_12 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 588.0
REGS1_k127_3537446_13 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 579.0
REGS1_k127_3537446_14 LysR substrate binding domain K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 503.0
REGS1_k127_3537446_15 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 379.0
REGS1_k127_3537446_16 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 376.0
REGS1_k127_3537446_17 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 372.0
REGS1_k127_3537446_18 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 342.0
REGS1_k127_3537446_19 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 290.0
REGS1_k127_3537446_2 Cysteine-rich domain - - - 7.598e-299 922.0
REGS1_k127_3537446_20 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000000000000000000000000000000000007978 231.0
REGS1_k127_3537446_21 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000000000000000000000003308 205.0
REGS1_k127_3537446_22 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000000338 206.0
REGS1_k127_3537446_23 DsrE/DsrF-like family K07236 - - 0.000000000000000000000000000000000000000000000000000000003155 201.0
REGS1_k127_3537446_24 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000005338 174.0
REGS1_k127_3537446_25 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000000003789 173.0
REGS1_k127_3537446_26 Cas6 Crispr - - - 0.0000000000000000000000000000000000000000000001008 175.0
REGS1_k127_3537446_27 SMART phosphoesterase PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000002876 173.0
REGS1_k127_3537446_28 - - - - 0.00000000000000000000000000000000000000000001014 166.0
REGS1_k127_3537446_29 DsrH like protein K07237 - - 0.00000000000000000000000000000000000002299 145.0
REGS1_k127_3537446_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 8.072e-259 805.0
REGS1_k127_3537446_30 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000002574 128.0
REGS1_k127_3537446_31 - - - - 0.00000000000000000000492 93.0
REGS1_k127_3537446_32 Sulfurtransferase TusA - - - 0.00000001942 56.0
REGS1_k127_3537446_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.479e-257 794.0
REGS1_k127_3537446_5 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 3.515e-247 769.0
REGS1_k127_3537446_6 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 3.821e-234 728.0
REGS1_k127_3537446_7 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 4.527e-223 695.0
REGS1_k127_3537446_8 AAA domain K02224 - 6.3.5.11,6.3.5.9 2.664e-222 699.0
REGS1_k127_3537446_9 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.736e-215 674.0
REGS1_k127_3574355_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1208.0
REGS1_k127_3574355_1 AAA domain K16898 - 3.6.4.12 0.0 1100.0
REGS1_k127_3574355_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.871e-220 687.0
REGS1_k127_3574355_3 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 552.0
REGS1_k127_3574355_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 437.0
REGS1_k127_3574355_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 293.0
REGS1_k127_3574355_6 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000001494 192.0
REGS1_k127_3574355_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000002526 187.0
REGS1_k127_3574355_8 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000901 183.0
REGS1_k127_3574355_9 - - - - 0.00000000000000000000000000000000000000000000008033 181.0
REGS1_k127_3624876_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 2.125e-320 987.0
REGS1_k127_3624876_1 V-type ATPase 116kDa subunit family K02123 - - 2.647e-254 799.0
REGS1_k127_3624876_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000005029 202.0
REGS1_k127_3624876_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000002529 206.0
REGS1_k127_3624876_12 V-type proton ATPase subunit E K02121 - - 0.00000000000000000000000000000000000000000000000000000001741 203.0
REGS1_k127_3624876_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000001613 193.0
REGS1_k127_3624876_14 ATP synthase (F/14-kDa) subunit - - - 0.0000000000000000000000000000000000002031 152.0
REGS1_k127_3624876_15 - - - - 0.00000000000000000000001664 103.0
REGS1_k127_3624876_16 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000001121 98.0
REGS1_k127_3624876_17 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000001819 89.0
REGS1_k127_3624876_18 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000193 72.0
REGS1_k127_3624876_2 PFAM Type II secretion system F domain K02653 - - 2.089e-196 618.0
REGS1_k127_3624876_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 529.0
REGS1_k127_3624876_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 445.0
REGS1_k127_3624876_5 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 443.0
REGS1_k127_3624876_6 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 428.0
REGS1_k127_3624876_7 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 363.0
REGS1_k127_3624876_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000003598 263.0
REGS1_k127_3624876_9 ATP synthase subunit C K02124 - - 0.000000000000000000000000000000000000000000000000000000000000000001251 229.0
REGS1_k127_3636572_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 591.0
REGS1_k127_3636572_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 518.0
REGS1_k127_3636572_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 319.0
REGS1_k127_3636572_3 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000002157 132.0
REGS1_k127_368187_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1120.0
REGS1_k127_368187_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 7.023e-296 923.0
REGS1_k127_368187_10 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 405.0
REGS1_k127_368187_11 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 384.0
REGS1_k127_368187_12 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 352.0
REGS1_k127_368187_13 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 349.0
REGS1_k127_368187_14 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 344.0
REGS1_k127_368187_15 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 339.0
REGS1_k127_368187_16 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 291.0
REGS1_k127_368187_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 289.0
REGS1_k127_368187_18 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001031 295.0
REGS1_k127_368187_19 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000000000000000000000000000007746 132.0
REGS1_k127_368187_2 AsmA family K07289 - - 1.187e-248 787.0
REGS1_k127_368187_20 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000004736 125.0
REGS1_k127_368187_21 ThiS family K03154 - - 0.000000000000000000001167 95.0
REGS1_k127_368187_22 - - - - 0.00000000000000000003841 94.0
REGS1_k127_368187_24 psiF repeat - - - 0.00002499 52.0
REGS1_k127_368187_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 3.514e-247 769.0
REGS1_k127_368187_4 Nitronate monooxygenase K00459 - 1.13.12.16 7.32e-231 718.0
REGS1_k127_368187_5 Involved in the biosynthesis of porphyrin-containing compound - - - 2.621e-206 647.0
REGS1_k127_368187_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 587.0
REGS1_k127_368187_7 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 511.0
REGS1_k127_368187_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 466.0
REGS1_k127_368187_9 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 410.0
REGS1_k127_3708575_0 fad dependent oxidoreductase K07137 - - 1.282e-287 889.0
REGS1_k127_3708575_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.752e-272 840.0
REGS1_k127_3708575_10 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 255.0
REGS1_k127_3708575_11 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.000000000000000000000000000000000000000000009854 167.0
REGS1_k127_3708575_12 Invasion gene expression up-regulator, SirB - - - 0.000000000000000000000000000000000000008534 150.0
REGS1_k127_3708575_13 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000001303 124.0
REGS1_k127_3708575_14 LysM domain - - - 0.0000000000000000000000697 110.0
REGS1_k127_3708575_15 TfoX C-terminal domain K07343 - - 0.0000000000000000004391 89.0
REGS1_k127_3708575_16 - - - - 0.0000000000000007273 83.0
REGS1_k127_3708575_17 Phospholipase/Carboxylesterase K06999 - - 0.000004284 53.0
REGS1_k127_3708575_2 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 4.713e-201 637.0
REGS1_k127_3708575_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 405.0
REGS1_k127_3708575_4 Arginase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 342.0
REGS1_k127_3708575_5 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 336.0
REGS1_k127_3708575_6 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 332.0
REGS1_k127_3708575_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 298.0
REGS1_k127_3708575_8 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 286.0
REGS1_k127_3708575_9 phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004383 286.0
REGS1_k127_3752459_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1354.0
REGS1_k127_3752459_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 365.0
REGS1_k127_3752459_2 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 346.0
REGS1_k127_3752459_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003655 272.0
REGS1_k127_3752459_4 response regulator K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000002233 238.0
REGS1_k127_3782093_1 Histidine kinase K20975 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 340.0
REGS1_k127_3782093_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007612 284.0
REGS1_k127_3782093_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000047 253.0
REGS1_k127_3782093_4 Histidine kinase K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000006268 187.0
REGS1_k127_3782093_5 ABC-type phosphate transport system, periplasmic component - - - 0.0000000000000000000000000000005157 127.0
REGS1_k127_3782093_6 - - - - 0.00000000001318 70.0
REGS1_k127_3782093_7 - - - - 0.000008247 51.0
REGS1_k127_3782093_8 Outer membrane protein beta-barrel domain - - - 0.00001739 54.0
REGS1_k127_38286_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 3.444e-219 694.0
REGS1_k127_38286_1 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 577.0
REGS1_k127_38286_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 526.0
REGS1_k127_38286_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 414.0
REGS1_k127_38286_4 2OG-Fe dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 397.0
REGS1_k127_38286_5 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 357.0
REGS1_k127_38286_6 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000001255 110.0
REGS1_k127_38286_7 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00651 - 2.3.1.46 0.000000000002866 66.0
REGS1_k127_3840549_0 TOBE-like domain K02045 - 3.6.3.25 1.089e-203 636.0
REGS1_k127_3840549_1 Binding-protein-dependent transport system inner membrane component K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 491.0
REGS1_k127_3840549_2 Binding-protein-dependent transport system inner membrane component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 484.0
REGS1_k127_3840549_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000007503 74.0
REGS1_k127_3880596_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 513.0
REGS1_k127_3880596_1 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001616 242.0
REGS1_k127_3880596_2 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.00000000000000000000000000000000000000000000000000142 184.0
REGS1_k127_3880596_3 PFAM HPP family protein K07168 - - 0.000000000000000000000000000000000000000001489 164.0
REGS1_k127_3880596_4 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000002594 126.0
REGS1_k127_3880596_5 Iron-sulphur cluster assembly - - - 0.000000000000000000000000008631 111.0
REGS1_k127_3885736_0 Collagenase K08303 - - 0.0 1062.0
REGS1_k127_3885736_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 592.0
REGS1_k127_3885736_10 - - - - 0.0000000000000000000000000000001079 126.0
REGS1_k127_3885736_12 - - - - 0.000000000000000001321 89.0
REGS1_k127_3885736_14 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00000000004471 70.0
REGS1_k127_3885736_2 PFAM DNA-repair protein, UmuC-like K03502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 488.0
REGS1_k127_3885736_3 AAA domain K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 435.0
REGS1_k127_3885736_4 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 287.0
REGS1_k127_3885736_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001445 255.0
REGS1_k127_3885736_6 capsule biosynthesis protein CapA K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 252.0
REGS1_k127_3885736_7 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000002395 188.0
REGS1_k127_3885736_8 Belongs to the peptidase S24 family K03503 - - 0.000000000000000000000000000000000000001149 151.0
REGS1_k127_3885736_9 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000009574 134.0
REGS1_k127_4035006_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.408e-254 786.0
REGS1_k127_4035006_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 406.0
REGS1_k127_4035006_2 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
REGS1_k127_4035006_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004203 270.0
REGS1_k127_4035006_4 PFAM Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001064 271.0
REGS1_k127_4035006_5 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000006966 226.0
REGS1_k127_4035006_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000009611 169.0
REGS1_k127_4035006_7 - - - - 0.0000000000000000000000000000000000000000000002035 174.0
REGS1_k127_4035006_8 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000000001175 164.0
REGS1_k127_4079765_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.148e-279 869.0
REGS1_k127_4079765_1 MscS Mechanosensitive ion channel - - - 1.224e-222 700.0
REGS1_k127_4079765_10 COG2346, Truncated hemoglobins K06886,K07006 - - 0.000000001617 61.0
REGS1_k127_4079765_2 Sugar (and other) transporter - - - 6.116e-215 673.0
REGS1_k127_4079765_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 445.0
REGS1_k127_4079765_4 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 433.0
REGS1_k127_4079765_5 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000001289 175.0
REGS1_k127_4079765_6 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000001594 101.0
REGS1_k127_4079765_7 spectrin binding K15502,K19947 - 1.14.13.225 0.000000000000000001405 93.0
REGS1_k127_4079765_8 Bacterial-like globin - - - 0.000000000006925 66.0
REGS1_k127_4079765_9 NAD(P)H-dependent FMN reductase - - - 0.00000000008574 66.0
REGS1_k127_4083813_0 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase - - - 0.0 1299.0
REGS1_k127_4083813_1 PFAM ABC transporter related - - - 0.0 1010.0
REGS1_k127_4083813_10 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 540.0
REGS1_k127_4083813_11 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 499.0
REGS1_k127_4083813_12 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 514.0
REGS1_k127_4083813_13 serine-type endopeptidase activity K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 503.0
REGS1_k127_4083813_14 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 363.0
REGS1_k127_4083813_15 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 351.0
REGS1_k127_4083813_16 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 335.0
REGS1_k127_4083813_17 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 327.0
REGS1_k127_4083813_18 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 310.0
REGS1_k127_4083813_19 PFAM response regulator receiver K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
REGS1_k127_4083813_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.139e-292 906.0
REGS1_k127_4083813_20 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000001412 223.0
REGS1_k127_4083813_21 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000005718 240.0
REGS1_k127_4083813_22 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000009306 168.0
REGS1_k127_4083813_23 membrane protein domain - - - 0.00000000000000000000000000000001373 139.0
REGS1_k127_4083813_24 Phosphotransferase System K11189 - - 0.0000000000000000000000000000002958 126.0
REGS1_k127_4083813_25 membrane protein domain - - - 0.000000000000000000000000004946 123.0
REGS1_k127_4083813_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 4.578e-292 907.0
REGS1_k127_4083813_4 K+ potassium transporter K03549 - - 1.06e-263 825.0
REGS1_k127_4083813_5 Glutamate-cysteine ligase K01919 - 6.3.2.2 3.476e-238 740.0
REGS1_k127_4083813_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 2.716e-220 688.0
REGS1_k127_4083813_7 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.452e-207 649.0
REGS1_k127_4083813_8 PFAM major facilitator superfamily MFS_1 K08218 - - 1.625e-198 629.0
REGS1_k127_4083813_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 4.976e-194 618.0
REGS1_k127_4107802_0 serine protease K07403 - - 5.257e-207 653.0
REGS1_k127_4107802_1 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 417.0
REGS1_k127_4107802_2 Mate efflux family protein K03327 - - 0.00000000000000000000000000000000000000000000000000000001156 201.0
REGS1_k127_4107802_3 - - - - 0.0000005238 58.0
REGS1_k127_4198383_0 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 565.0
REGS1_k127_4198383_1 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 511.0
REGS1_k127_4198383_2 PFAM Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 429.0
REGS1_k127_4198383_3 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 319.0
REGS1_k127_4198383_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
REGS1_k127_4198383_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000008216 210.0
REGS1_k127_4198383_6 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000000001996 173.0
REGS1_k127_4198383_7 ABC transporter transmembrane region K11004 - - 0.0000000000000000000000000000001204 125.0
REGS1_k127_4258561_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1835.0
REGS1_k127_4258561_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 620.0
REGS1_k127_4258561_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000001111 233.0
REGS1_k127_4258561_11 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000681 172.0
REGS1_k127_4258561_12 - - - - 0.0000000000000000000000000000000000000000000281 169.0
REGS1_k127_4258561_13 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000015 160.0
REGS1_k127_4258561_14 - - - - 0.00000000000000000000000000000000000000001817 158.0
REGS1_k127_4258561_2 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 454.0
REGS1_k127_4258561_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 446.0
REGS1_k127_4258561_4 response to antibiotic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 372.0
REGS1_k127_4258561_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 347.0
REGS1_k127_4258561_6 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 342.0
REGS1_k127_4258561_7 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 304.0
REGS1_k127_4258561_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005562 274.0
REGS1_k127_4258561_9 polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 237.0
REGS1_k127_4264368_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1103.0
REGS1_k127_4264368_1 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 289.0
REGS1_k127_4264368_2 - - - - 0.0000000000000000000000000000000000000000000000000000000007745 205.0
REGS1_k127_4264368_3 - - - - 0.000000000000000000000000000000000000000009528 160.0
REGS1_k127_4264368_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000009574 134.0
REGS1_k127_4380327_0 Histidine Phosphotransfer domain K02487,K06596 - - 0.0 1695.0
REGS1_k127_4380327_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1194.0
REGS1_k127_4380327_10 histidine kinase HAMP region domain protein K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 616.0
REGS1_k127_4380327_11 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 579.0
REGS1_k127_4380327_12 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 507.0
REGS1_k127_4380327_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 349.0
REGS1_k127_4380327_14 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 351.0
REGS1_k127_4380327_15 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 346.0
REGS1_k127_4380327_16 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 295.0
REGS1_k127_4380327_17 Phytochelatin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 289.0
REGS1_k127_4380327_18 Copper resistance protein B precursor (CopB) K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000005697 228.0
REGS1_k127_4380327_19 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000002482 216.0
REGS1_k127_4380327_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1115.0
REGS1_k127_4380327_20 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000003482 214.0
REGS1_k127_4380327_21 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000000000000000000000002604 200.0
REGS1_k127_4380327_22 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000000000000000000000009007 187.0
REGS1_k127_4380327_23 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000001336 156.0
REGS1_k127_4380327_24 Pfam Glutaredoxin - - - 0.0000000000000000000000000000000004542 138.0
REGS1_k127_4380327_25 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000000007405 115.0
REGS1_k127_4380327_26 - - - - 0.000000000000000000000000002578 115.0
REGS1_k127_4380327_27 OmpA-like transmembrane domain K03286 - - 0.000000000000000000000002396 109.0
REGS1_k127_4380327_28 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000004666 94.0
REGS1_k127_4380327_29 - - - - 0.0000000000000007423 89.0
REGS1_k127_4380327_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1062.0
REGS1_k127_4380327_31 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000001097 59.0
REGS1_k127_4380327_32 COG3209 Rhs family protein - - - 0.00000008862 59.0
REGS1_k127_4380327_4 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1061.0
REGS1_k127_4380327_5 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 4.768e-288 892.0
REGS1_k127_4380327_6 Amidohydrolase family K01465 - 3.5.2.3 4.324e-241 752.0
REGS1_k127_4380327_7 Multicopper oxidase - - - 2.134e-233 736.0
REGS1_k127_4380327_8 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 2.934e-228 713.0
REGS1_k127_4380327_9 AAA ATPase domain - - - 3.238e-216 686.0
REGS1_k127_4472477_0 AcrB/AcrD/AcrF family - - - 0.0 1467.0
REGS1_k127_4472477_1 PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 440.0
REGS1_k127_4472477_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000284 207.0
REGS1_k127_4472477_3 Copper binding periplasmic protein CusF K07810 - - 0.0000000000000001439 89.0
REGS1_k127_4472610_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1614.0
REGS1_k127_4472610_1 PFAM DNA polymerase III chi subunit HolC K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000001991 208.0
REGS1_k127_4472610_2 Protein of unknown function (DUF1622) - - - 0.0000001562 57.0
REGS1_k127_4504964_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.839e-272 856.0
REGS1_k127_4504964_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 5.621e-196 616.0
REGS1_k127_4504964_10 - - - - 0.000000000000000000000000000001362 133.0
REGS1_k127_4504964_11 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000004593 118.0
REGS1_k127_4504964_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000005258 118.0
REGS1_k127_4504964_13 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000006307 92.0
REGS1_k127_4504964_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 466.0
REGS1_k127_4504964_3 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 412.0
REGS1_k127_4504964_4 radical SAM protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 394.0
REGS1_k127_4504964_5 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 359.0
REGS1_k127_4504964_6 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000168 271.0
REGS1_k127_4504964_7 tRNA cytidylyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000009584 217.0
REGS1_k127_4504964_8 helix_turn_helix, mercury resistance K19591,K19592 - - 0.000000000000000000000000000000000000000000000000007846 183.0
REGS1_k127_4504964_9 - - - - 0.00000000000000000000000000000000000000000000001074 186.0
REGS1_k127_4556393_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1560.0
REGS1_k127_4556393_1 major facilitator superfamily K03446 - - 1.783e-256 797.0
REGS1_k127_4556393_10 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 468.0
REGS1_k127_4556393_11 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 378.0
REGS1_k127_4556393_12 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 367.0
REGS1_k127_4556393_13 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 308.0
REGS1_k127_4556393_14 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 284.0
REGS1_k127_4556393_15 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 263.0
REGS1_k127_4556393_16 Outer membrane protein V K07274 - - 0.0000000000000000000000000000000000000000000000000000000002762 213.0
REGS1_k127_4556393_17 Transcription regulator that can specifically activate or repress expression of target genes K06075 - - 0.0000000000000000000000000000000000000000000001677 171.0
REGS1_k127_4556393_18 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000004738 160.0
REGS1_k127_4556393_19 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000001683 139.0
REGS1_k127_4556393_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.322e-246 764.0
REGS1_k127_4556393_20 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000000005565 125.0
REGS1_k127_4556393_21 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000007275 118.0
REGS1_k127_4556393_22 Protein of unknown function (DUF3460) - - - 0.00000377 49.0
REGS1_k127_4556393_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.147e-238 744.0
REGS1_k127_4556393_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 600.0
REGS1_k127_4556393_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 576.0
REGS1_k127_4556393_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 550.0
REGS1_k127_4556393_7 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 531.0
REGS1_k127_4556393_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 494.0
REGS1_k127_4556393_9 Rhodanese Homology Domain K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 483.0
REGS1_k127_457322_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 3.089e-308 950.0
REGS1_k127_457322_1 Glutamine synthetase, catalytic domain K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.447e-294 905.0
REGS1_k127_457322_10 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 457.0
REGS1_k127_457322_11 chlorophyll binding K02690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 451.0
REGS1_k127_457322_12 HNH endonuclease K07454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 410.0
REGS1_k127_457322_13 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 383.0
REGS1_k127_457322_14 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 357.0
REGS1_k127_457322_15 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 302.0
REGS1_k127_457322_16 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 300.0
REGS1_k127_457322_17 Domain of unknown function (DUF386) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003879 266.0
REGS1_k127_457322_18 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001013 244.0
REGS1_k127_457322_19 - - - - 0.00000000000000000000000000000000000000000000000000000000001324 209.0
REGS1_k127_457322_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 4.983e-291 896.0
REGS1_k127_457322_20 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000000000000003873 171.0
REGS1_k127_457322_21 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000000000000000000005026 168.0
REGS1_k127_457322_22 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000000000000000002824 149.0
REGS1_k127_457322_23 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000003276 141.0
REGS1_k127_457322_24 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000003291 145.0
REGS1_k127_457322_25 OmpA-like transmembrane domain K03286 - - 0.00000000000000000000000000001678 126.0
REGS1_k127_457322_26 Protein of unknown function (DUF1289) K06938 - - 0.00000000000000005698 85.0
REGS1_k127_457322_3 Peptidase family U32 C-terminal domain K08303 - - 6.109e-272 842.0
REGS1_k127_457322_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.411e-245 758.0
REGS1_k127_457322_5 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 3.472e-241 752.0
REGS1_k127_457322_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 563.0
REGS1_k127_457322_7 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 569.0
REGS1_k127_457322_8 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 519.0
REGS1_k127_457322_9 Bacterial lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 470.0
REGS1_k127_4612161_0 Sugar (and other) transporter - - - 1.122e-301 931.0
REGS1_k127_4612161_1 anti-sigma regulatory factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 438.0
REGS1_k127_4612161_11 HEAT repeats - - - 0.000000000000000000000005819 118.0
REGS1_k127_4612161_12 TniQ - - - 0.0000000000116 69.0
REGS1_k127_4612161_13 Bacterial extracellular solute-binding protein K02048 - - 0.0006215 44.0
REGS1_k127_4612161_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 374.0
REGS1_k127_4612161_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 353.0
REGS1_k127_4612161_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 351.0
REGS1_k127_4612161_5 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 308.0
REGS1_k127_4612161_6 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 302.0
REGS1_k127_4612161_7 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000001085 181.0
REGS1_k127_4612161_8 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000001481 183.0
REGS1_k127_4612161_9 - K17762 - - 0.0000000000000000000000000000000000000000000167 165.0
REGS1_k127_4622767_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 3.001e-256 799.0
REGS1_k127_4622767_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 6.008e-195 616.0
REGS1_k127_4622767_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 607.0
REGS1_k127_4622767_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 446.0
REGS1_k127_4622767_4 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 411.0
REGS1_k127_4622767_5 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 342.0
REGS1_k127_4622767_6 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000000000649 145.0
REGS1_k127_4622767_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000005548 51.0
REGS1_k127_4628572_0 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 364.0
REGS1_k127_4628572_2 - - - - 0.0000000000000000000008904 97.0
REGS1_k127_4628572_3 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000004734 63.0
REGS1_k127_4628572_5 - - - - 0.0002447 49.0
REGS1_k127_4705843_0 PFAM ABC-1 domain protein K03688 - - 3.593e-279 867.0
REGS1_k127_4705843_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.946e-257 797.0
REGS1_k127_4705843_10 Transcriptional regulator K18304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001048 254.0
REGS1_k127_4705843_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000818 249.0
REGS1_k127_4705843_12 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000003095 227.0
REGS1_k127_4705843_13 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000000000001147 90.0
REGS1_k127_4705843_14 sequence-specific DNA binding - - - 0.000000000000000000989 89.0
REGS1_k127_4705843_15 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000003749 62.0
REGS1_k127_4705843_2 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 9.466e-195 623.0
REGS1_k127_4705843_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 595.0
REGS1_k127_4705843_4 Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 576.0
REGS1_k127_4705843_5 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 413.0
REGS1_k127_4705843_6 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 355.0
REGS1_k127_4705843_7 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 311.0
REGS1_k127_4705843_8 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006867 273.0
REGS1_k127_4705843_9 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
REGS1_k127_4779728_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1200.0
REGS1_k127_4779728_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.695e-258 800.0
REGS1_k127_4779728_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001579 255.0
REGS1_k127_4779728_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000811 247.0
REGS1_k127_4779728_12 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000004885 243.0
REGS1_k127_4779728_13 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006244 232.0
REGS1_k127_4779728_14 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000005325 226.0
REGS1_k127_4779728_15 Bacterial-like globin - - - 0.0000000000000000000000000000000000000000000000000000000000003184 215.0
REGS1_k127_4779728_16 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000005507 221.0
REGS1_k127_4779728_17 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
REGS1_k127_4779728_18 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000004514 192.0
REGS1_k127_4779728_19 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000001418 186.0
REGS1_k127_4779728_2 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 8.988e-233 724.0
REGS1_k127_4779728_20 Helix-turn-helix domain K15539 - - 0.000000000000000000000000000000000000002825 160.0
REGS1_k127_4779728_21 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000000000005208 139.0
REGS1_k127_4779728_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.929e-224 699.0
REGS1_k127_4779728_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 6.295e-204 639.0
REGS1_k127_4779728_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 537.0
REGS1_k127_4779728_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 402.0
REGS1_k127_4779728_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 372.0
REGS1_k127_4779728_8 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 307.0
REGS1_k127_4779728_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 304.0
REGS1_k127_484109_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1277.0
REGS1_k127_484109_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 7.397e-215 669.0
REGS1_k127_484109_10 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000001426 191.0
REGS1_k127_484109_11 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000005643 148.0
REGS1_k127_484109_12 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000001207 112.0
REGS1_k127_484109_13 - - - - 0.00000000000000000007532 93.0
REGS1_k127_484109_14 Bacterial extracellular solute-binding protein K02048 - - 0.0006215 44.0
REGS1_k127_484109_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 595.0
REGS1_k127_484109_3 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 456.0
REGS1_k127_484109_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 308.0
REGS1_k127_484109_5 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005985 238.0
REGS1_k127_484109_6 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000000000000000000000000008939 234.0
REGS1_k127_484109_7 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000001149 231.0
REGS1_k127_484109_8 efflux transmembrane transporter activity K15725 - - 0.0000000000000000000000000000000000000000000000000000000004019 218.0
REGS1_k127_484109_9 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000003178 193.0
REGS1_k127_4917783_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1214.0
REGS1_k127_4917783_1 Sulfate permease family K03321 - - 1.874e-244 766.0
REGS1_k127_4917783_10 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000001467 176.0
REGS1_k127_4917783_11 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000000001211 166.0
REGS1_k127_4917783_12 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000000000000000001958 131.0
REGS1_k127_4917783_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000001803 115.0
REGS1_k127_4917783_14 mttA/Hcf106 family K03116 - - 0.000000000000000000001417 95.0
REGS1_k127_4917783_15 - - - - 0.00000000004918 65.0
REGS1_k127_4917783_2 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 4.834e-218 677.0
REGS1_k127_4917783_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 6.427e-206 645.0
REGS1_k127_4917783_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 472.0
REGS1_k127_4917783_5 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 468.0
REGS1_k127_4917783_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 322.0
REGS1_k127_4917783_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 319.0
REGS1_k127_4917783_8 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 301.0
REGS1_k127_4917783_9 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000001322 233.0
REGS1_k127_4937586_0 Formate acetyltransferase K00656 - 2.3.1.54 1.815e-294 920.0
REGS1_k127_4937586_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 4.03e-294 908.0
REGS1_k127_4961761_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1304.0
REGS1_k127_4961761_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1020.0
REGS1_k127_4961761_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.134e-279 862.0
REGS1_k127_4961761_3 DJ-1/PfpI family K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002575 274.0
REGS1_k127_4961761_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000351 207.0
REGS1_k127_4961761_5 SMART phosphoesterase PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000405 180.0
REGS1_k127_4961761_6 - - - - 0.00000000000000000000000000000000000000000000000008229 181.0
REGS1_k127_4991035_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.655e-316 972.0
REGS1_k127_4991035_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 1.036e-207 655.0
REGS1_k127_4991035_10 Immunity protein 42 - - - 0.000000000000001341 83.0
REGS1_k127_4991035_11 - - - - 0.000000001167 65.0
REGS1_k127_4991035_12 - - - - 0.0008264 43.0
REGS1_k127_4991035_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 483.0
REGS1_k127_4991035_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 379.0
REGS1_k127_4991035_4 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 324.0
REGS1_k127_4991035_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 293.0
REGS1_k127_4991035_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000009431 253.0
REGS1_k127_4991035_7 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000000000000000002288 151.0
REGS1_k127_4991035_8 transport-associated - - - 0.00000000000000000000000000000006914 133.0
REGS1_k127_4991035_9 - - - - 0.00000000000000112 88.0
REGS1_k127_4998980_0 Alpha-2-Macroglobulin K06894 - - 0.0 2081.0
REGS1_k127_4998980_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 3.907e-275 867.0
REGS1_k127_4998980_2 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 497.0
REGS1_k127_4998980_3 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 428.0
REGS1_k127_4998980_4 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 419.0
REGS1_k127_4998980_5 response regulator K19622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 353.0
REGS1_k127_5010170_0 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 0.0 1090.0
REGS1_k127_5010170_1 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0 1070.0
REGS1_k127_5010170_10 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000000000000000000001421 222.0
REGS1_k127_5010170_11 - - - - 0.00000000000000000000000000000000000000000000001745 177.0
REGS1_k127_5010170_12 Uncharacterized ACR, COG1993 - - - 0.000000000000000000000000000000000001618 140.0
REGS1_k127_5010170_2 ABC transporter K06020 - 3.6.3.25 9.482e-318 977.0
REGS1_k127_5010170_3 Acyl-CoA dehydrogenases K06445 - - 3.105e-301 945.0
REGS1_k127_5010170_4 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 469.0
REGS1_k127_5010170_5 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 433.0
REGS1_k127_5010170_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 404.0
REGS1_k127_5010170_7 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 302.0
REGS1_k127_5010170_8 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
REGS1_k127_5010170_9 PFAM thioesterase superfamily protein K10806 - - 0.00000000000000000000000000000000000000000000000000000000000000003595 224.0
REGS1_k127_5029450_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 362.0
REGS1_k127_5029450_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 302.0
REGS1_k127_5029450_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000001118 184.0
REGS1_k127_5029450_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000003524 81.0
REGS1_k127_5043132_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1165.0
REGS1_k127_5043132_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 577.0
REGS1_k127_5043132_10 Putative zinc- or iron-chelating domain - - - 0.0000532 49.0
REGS1_k127_5043132_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 501.0
REGS1_k127_5043132_3 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 430.0
REGS1_k127_5043132_4 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 289.0
REGS1_k127_5043132_5 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007802 242.0
REGS1_k127_5043132_6 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000001276 207.0
REGS1_k127_5043132_7 - - - - 0.00000000000000000000000000000000000000000000009306 175.0
REGS1_k127_5043132_8 NmrA-like family K19267 - 1.6.5.2 0.0000000000000000000000000000000002584 134.0
REGS1_k127_5043132_9 Transposase - - - 0.000000000000000000000000009298 113.0
REGS1_k127_5055423_0 TPR repeat - - - 2.777e-198 632.0
REGS1_k127_5055423_1 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000000000000000001805 136.0
REGS1_k127_5055423_2 PFAM TPR repeat-containing protein - - - 0.00000000000000009452 85.0
REGS1_k127_5055423_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000002609 59.0
REGS1_k127_5067661_0 Bacteriophage head to tail connecting protein - - - 4.202e-229 722.0
REGS1_k127_5067661_1 Participates in initiation and elongation during chromosome replication - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 524.0
REGS1_k127_5067661_2 Protein of unknown function (DUF3037) - - - 0.000000000000000000000000000000000000008813 155.0
REGS1_k127_5067661_3 - - - - 0.00000000000000000000000001207 119.0
REGS1_k127_5067661_5 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.0000000000007413 77.0
REGS1_k127_5067661_6 - - - - 0.000001791 54.0
REGS1_k127_5067661_7 - - - - 0.00003431 55.0
REGS1_k127_5137498_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1363.0
REGS1_k127_5137498_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 1.143e-199 627.0
REGS1_k127_5137498_10 HNH nucleases - - - 0.00000000000000000000000000000000000000000000004953 172.0
REGS1_k127_5137498_11 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000432 104.0
REGS1_k127_5137498_12 S4 domain K14761 - - 0.00000000000000006715 80.0
REGS1_k127_5137498_13 - - - - 0.00000000000823 67.0
REGS1_k127_5137498_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 459.0
REGS1_k127_5137498_3 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 457.0
REGS1_k127_5137498_4 beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 361.0
REGS1_k127_5137498_5 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 314.0
REGS1_k127_5137498_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 305.0
REGS1_k127_5137498_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 295.0
REGS1_k127_5137498_8 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001926 241.0
REGS1_k127_5137498_9 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000000000000000000000000000002465 207.0
REGS1_k127_5167144_0 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 0.0 999.0
REGS1_k127_5167144_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.257e-243 759.0
REGS1_k127_5167144_10 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001278 271.0
REGS1_k127_5167144_11 Histidine kinase K20975 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001546 297.0
REGS1_k127_5167144_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005569 258.0
REGS1_k127_5167144_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000000005797 220.0
REGS1_k127_5167144_14 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000002193 234.0
REGS1_k127_5167144_15 Ribosomal protein L9, N-terminal domain K02939 - - 0.000000000000000000000000000000000000000000000000000000001998 205.0
REGS1_k127_5167144_16 tail collar domain protein - - - 0.0000000000000000000000000000000000000000000000000037 203.0
REGS1_k127_5167144_17 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000118 180.0
REGS1_k127_5167144_18 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000003089 176.0
REGS1_k127_5167144_19 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000004083 156.0
REGS1_k127_5167144_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.463e-203 633.0
REGS1_k127_5167144_20 - - - - 0.0000000000000000000000000000000000000001391 156.0
REGS1_k127_5167144_22 tail collar domain protein - - - 0.0000000000000000000000000000000002383 138.0
REGS1_k127_5167144_23 Cytochrome c - - - 0.000000000000000000000000000005503 124.0
REGS1_k127_5167144_24 DNA replication, synthesis of RNA primer K02686 - - 0.0000000000000000000000000000282 119.0
REGS1_k127_5167144_25 Peptidase M15A K03791 - - 0.0000000000000000000000000002222 120.0
REGS1_k127_5167144_26 cellulose 1,4-beta-cellobiosidase activity - - - 0.0000000000000000000000000005571 129.0
REGS1_k127_5167144_27 cellulose 1,4-beta-cellobiosidase activity - - - 0.0000000000000000000000000006099 130.0
REGS1_k127_5167144_28 Protein of unknown function (DUF3106) - - - 0.000000000000000000000277 101.0
REGS1_k127_5167144_3 transport system, periplasmic component - - - 3.218e-195 618.0
REGS1_k127_5167144_30 - - - - 0.00000000000000000002316 93.0
REGS1_k127_5167144_31 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000004793 106.0
REGS1_k127_5167144_34 - - - - 0.0000000004368 72.0
REGS1_k127_5167144_35 Protein of unknown function (DUF2793) - - - 0.0000006335 62.0
REGS1_k127_5167144_36 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.00000715 56.0
REGS1_k127_5167144_37 Protein of unknown function (DUF2793) - - - 0.00005948 56.0
REGS1_k127_5167144_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 574.0
REGS1_k127_5167144_5 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 481.0
REGS1_k127_5167144_6 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 329.0
REGS1_k127_5167144_7 PFAM Peptidase S24 S26A S26B, conserved region K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 319.0
REGS1_k127_5167144_8 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 300.0
REGS1_k127_5167144_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002746 280.0
REGS1_k127_5191729_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 5.242e-237 739.0
REGS1_k127_5191729_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 2.071e-227 707.0
REGS1_k127_5191729_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000383 218.0
REGS1_k127_5191729_3 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000005182 212.0
REGS1_k127_5191729_4 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000001609 200.0
REGS1_k127_5191729_5 Chalcone isomerase-like - - - 0.00000000000000003527 85.0
REGS1_k127_5191729_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000009955 72.0
REGS1_k127_5215080_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1169.0
REGS1_k127_5215080_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1076.0
REGS1_k127_5215080_10 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 519.0
REGS1_k127_5215080_11 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 530.0
REGS1_k127_5215080_12 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 447.0
REGS1_k127_5215080_13 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 362.0
REGS1_k127_5215080_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 325.0
REGS1_k127_5215080_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 296.0
REGS1_k127_5215080_16 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 284.0
REGS1_k127_5215080_17 response regulator K14979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006277 281.0
REGS1_k127_5215080_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001503 279.0
REGS1_k127_5215080_19 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000194 270.0
REGS1_k127_5215080_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.55e-273 841.0
REGS1_k127_5215080_20 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005016 259.0
REGS1_k127_5215080_21 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000000005118 231.0
REGS1_k127_5215080_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000007624 211.0
REGS1_k127_5215080_23 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000000009168 205.0
REGS1_k127_5215080_24 - - - - 0.00000000000000000000000000000000000000000000000000001628 200.0
REGS1_k127_5215080_25 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000006892 194.0
REGS1_k127_5215080_26 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000000000000000000000001719 183.0
REGS1_k127_5215080_27 prepilin-type N-terminal cleavage methylation K02456 - - 0.00000000000000000000000000000000000000000000001122 174.0
REGS1_k127_5215080_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000001035 152.0
REGS1_k127_5215080_29 carbon utilization - - - 0.000000000000000000000000000000000000434 150.0
REGS1_k127_5215080_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.571e-271 841.0
REGS1_k127_5215080_30 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000002751 118.0
REGS1_k127_5215080_31 Sh3 type 3 domain protein K02450,K12132 - 2.7.11.1 0.00000000000000000000000000002876 132.0
REGS1_k127_5215080_32 - - - - 0.00000000000000000000000000005189 122.0
REGS1_k127_5215080_33 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000002461 117.0
REGS1_k127_5215080_34 - - - - 0.000000000000000002162 93.0
REGS1_k127_5215080_35 oxidase, assembly K02258 - - 0.0002073 50.0
REGS1_k127_5215080_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 7.627e-264 814.0
REGS1_k127_5215080_5 Ammonium Transporter Family K03320,K06580 - - 1.548e-241 748.0
REGS1_k127_5215080_6 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.127e-238 753.0
REGS1_k127_5215080_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.291e-233 728.0
REGS1_k127_5215080_8 type II and III secretion system protein K02453 - - 7.321e-228 729.0
REGS1_k127_5215080_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 599.0
REGS1_k127_5302092_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1004.0
REGS1_k127_5302092_1 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 1.941e-235 758.0
REGS1_k127_5302092_10 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000009654 209.0
REGS1_k127_5302092_11 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000008055 201.0
REGS1_k127_5302092_12 Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000000000000000000005496 151.0
REGS1_k127_5302092_13 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000004046 144.0
REGS1_k127_5302092_14 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000002473 107.0
REGS1_k127_5302092_15 Aldo/keto reductase family - - - 0.00000000000000000000002024 100.0
REGS1_k127_5302092_17 - - - - 0.000000001974 59.0
REGS1_k127_5302092_18 PFAM Metal-dependent phosphohydrolase, HD K07814 - - 0.000000003651 59.0
REGS1_k127_5302092_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 4.253e-205 644.0
REGS1_k127_5302092_3 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 470.0
REGS1_k127_5302092_4 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 461.0
REGS1_k127_5302092_5 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 468.0
REGS1_k127_5302092_6 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 355.0
REGS1_k127_5302092_7 Methyltransferase domain K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 320.0
REGS1_k127_5302092_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 311.0
REGS1_k127_5302092_9 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005717 253.0
REGS1_k127_5410146_0 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 1.604e-273 848.0
REGS1_k127_5410146_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.308e-215 677.0
REGS1_k127_5410146_10 4Fe-4S binding domain - - - 0.00000000000000000000000000000000001779 135.0
REGS1_k127_5410146_11 PFAM NifZ family protein K02597 - - 0.0000000000000000000000000001492 118.0
REGS1_k127_5410146_12 NifT/FixU protein K02593 - - 0.00000000000000000000000001452 110.0
REGS1_k127_5410146_13 Protein of unknown function (DUF3024) - - - 0.00000000000000000000000008691 114.0
REGS1_k127_5410146_14 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000001643 72.0
REGS1_k127_5410146_15 - - - - 0.00000376 54.0
REGS1_k127_5410146_2 Nif-specific regulatory protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 598.0
REGS1_k127_5410146_3 PFAM EAL domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 420.0
REGS1_k127_5410146_4 SIR2-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 323.0
REGS1_k127_5410146_5 LRV protein FeS4 cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000714 262.0
REGS1_k127_5410146_6 Iron-sulfur cluster assembly enzyme K22068 - - 0.00000000000000000000000000000000000000000000000000000000000000000824 227.0
REGS1_k127_5410146_7 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000004938 221.0
REGS1_k127_5410146_8 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000000000000614 160.0
REGS1_k127_5410146_9 NifZ domain K02597 - - 0.0000000000000000000000000000000000006373 142.0
REGS1_k127_5416336_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 5.225e-231 729.0
REGS1_k127_5416336_1 Belongs to the DegT DnrJ EryC1 family - - - 7.617e-212 661.0
REGS1_k127_5416336_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 595.0
REGS1_k127_5416336_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 448.0
REGS1_k127_5416336_4 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002928 279.0
REGS1_k127_5416336_5 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000004714 186.0
REGS1_k127_5416336_6 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000000000000002569 186.0
REGS1_k127_5483915_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.226e-195 619.0
REGS1_k127_5483915_1 PFAM iron permease FTR1 K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 382.0
REGS1_k127_5483915_10 - - - - 0.0004405 51.0
REGS1_k127_5483915_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 331.0
REGS1_k127_5483915_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005494 270.0
REGS1_k127_5483915_4 PFAM ferric-uptake regulator K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005586 239.0
REGS1_k127_5483915_5 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000000000000000001205 198.0
REGS1_k127_5483915_6 - - - - 0.000000000000000000000000000000000000000000000000006024 190.0
REGS1_k127_5483915_7 Cupredoxin-like domain - - - 0.0000000000000000000000000000000003683 135.0
REGS1_k127_5483915_8 - - - - 0.0000000000000005321 84.0
REGS1_k127_5483915_9 Transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000001602 61.0
REGS1_k127_5509878_0 cytochrome c oxidase cbb3-type, subunit II K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 368.0
REGS1_k127_5509878_1 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003906 259.0
REGS1_k127_5509878_2 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000006466 237.0
REGS1_k127_5509878_3 PFAM copper resistance D domain protein K07245 - - 0.0000000000000006389 89.0
REGS1_k127_5509878_4 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000891 84.0
REGS1_k127_5509878_5 Copper resistance protein K07156 - - 0.00000000001112 74.0
REGS1_k127_5529167_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1045.0
REGS1_k127_5529167_1 Sugar (and other) transporter - - - 4.676e-225 704.0
REGS1_k127_5529167_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 456.0
REGS1_k127_5529167_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 467.0
REGS1_k127_5529167_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008585 259.0
REGS1_k127_5529167_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001867 256.0
REGS1_k127_5529167_6 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000008797 209.0
REGS1_k127_5529167_7 - - - - 0.00000000001584 69.0
REGS1_k127_5606790_0 MacB-like periplasmic core domain K02004 - - 1.581e-215 674.0
REGS1_k127_5606790_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 602.0
REGS1_k127_5606790_2 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 528.0
REGS1_k127_5606790_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 364.0
REGS1_k127_5606790_4 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 357.0
REGS1_k127_5606790_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 306.0
REGS1_k127_5693530_0 Hsp90 protein K04079 - - 0.0 1107.0
REGS1_k127_5693530_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 612.0
REGS1_k127_5693530_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 419.0
REGS1_k127_5763007_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1211.0
REGS1_k127_5763007_1 HELICc2 K03722 - 3.6.4.12 0.0 1062.0
REGS1_k127_5763007_10 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002001 271.0
REGS1_k127_5763007_11 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001522 252.0
REGS1_k127_5763007_12 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000002573 241.0
REGS1_k127_5763007_13 Soluble NSF attachment protein, SNAP - - - 0.00000000000000000000000000000000000000000000000000000000000002485 244.0
REGS1_k127_5763007_15 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000001518 196.0
REGS1_k127_5763007_16 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000002249 188.0
REGS1_k127_5763007_17 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000001361 177.0
REGS1_k127_5763007_18 PFAM Ankyrin repeat K06867 - - 0.000000000000000000000000000000000000000002791 171.0
REGS1_k127_5763007_19 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000001811 145.0
REGS1_k127_5763007_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 8.751e-292 913.0
REGS1_k127_5763007_20 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000000005285 126.0
REGS1_k127_5763007_21 Acetyltransferase (GNAT) domain - - - 0.000000000000001183 81.0
REGS1_k127_5763007_22 Protein conserved in bacteria - - - 0.0000000000001573 74.0
REGS1_k127_5763007_23 Ankyrin repeats (many copies) K10380,K15502,K15503 - - 0.0000000000003332 78.0
REGS1_k127_5763007_24 Transposase IS200 like K07491 - - 0.0000000000005034 71.0
REGS1_k127_5763007_25 - - - - 0.000000000003095 73.0
REGS1_k127_5763007_3 PFAM DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 534.0
REGS1_k127_5763007_4 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 402.0
REGS1_k127_5763007_5 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 410.0
REGS1_k127_5763007_6 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 370.0
REGS1_k127_5763007_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 334.0
REGS1_k127_5763007_8 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 308.0
REGS1_k127_5763007_9 DSBA Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
REGS1_k127_5792904_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 1.805e-224 702.0
REGS1_k127_5792904_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 1.545e-201 638.0
REGS1_k127_5792904_10 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 295.0
REGS1_k127_5792904_11 Bacterial dnaA protein K10763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 295.0
REGS1_k127_5792904_12 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003826 249.0
REGS1_k127_5792904_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005673 234.0
REGS1_k127_5792904_14 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000001145 216.0
REGS1_k127_5792904_15 pathogenesis - - - 0.000000000000000000000000000000000000000000000000000000002425 206.0
REGS1_k127_5792904_16 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000002872 171.0
REGS1_k127_5792904_17 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000000005286 157.0
REGS1_k127_5792904_18 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000000003964 110.0
REGS1_k127_5792904_19 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000001502 122.0
REGS1_k127_5792904_2 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 576.0
REGS1_k127_5792904_20 PFAM Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000009201 109.0
REGS1_k127_5792904_21 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000006671 90.0
REGS1_k127_5792904_3 Protein of unknown function (DUF817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 460.0
REGS1_k127_5792904_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 434.0
REGS1_k127_5792904_5 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 369.0
REGS1_k127_5792904_6 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 357.0
REGS1_k127_5792904_7 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 363.0
REGS1_k127_5792904_8 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 306.0
REGS1_k127_5792904_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 308.0
REGS1_k127_5846429_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 2.714e-244 756.0
REGS1_k127_5846429_1 ABC transporter C-terminal domain K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009562 598.0
REGS1_k127_5846429_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 316.0
REGS1_k127_5846429_11 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 317.0
REGS1_k127_5846429_12 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 293.0
REGS1_k127_5846429_13 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001994 249.0
REGS1_k127_5846429_14 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005257 245.0
REGS1_k127_5846429_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000002063 229.0
REGS1_k127_5846429_16 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001927 212.0
REGS1_k127_5846429_17 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000000000008008 154.0
REGS1_k127_5846429_18 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000000001143 136.0
REGS1_k127_5846429_19 PQ loop repeat K15383 - - 0.0000000000000000000000000000004061 125.0
REGS1_k127_5846429_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 486.0
REGS1_k127_5846429_20 Belongs to the phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000003206 72.0
REGS1_k127_5846429_22 Protein of unknown function (DUF2621) - - - 0.000000004095 65.0
REGS1_k127_5846429_23 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000608 53.0
REGS1_k127_5846429_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 457.0
REGS1_k127_5846429_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 452.0
REGS1_k127_5846429_5 TRAP transporter solute receptor TAXI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 452.0
REGS1_k127_5846429_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 418.0
REGS1_k127_5846429_7 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008965 414.0
REGS1_k127_5846429_8 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 327.0
REGS1_k127_5846429_9 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 324.0
REGS1_k127_5851707_0 Neisseria PilC beta-propeller domain K02674 - - 1.802e-294 969.0
REGS1_k127_5851707_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.02e-263 811.0
REGS1_k127_5851707_10 Response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000000000001127 185.0
REGS1_k127_5851707_11 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000004982 164.0
REGS1_k127_5851707_12 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000000003227 162.0
REGS1_k127_5851707_13 type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000000000000000001021 152.0
REGS1_k127_5851707_14 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000000000000003195 144.0
REGS1_k127_5851707_15 Type II transport protein GspH K08084 - - 0.0000000000000000000000000000000000008517 147.0
REGS1_k127_5851707_16 CheW-like domain - - - 0.00000000000000000000000000000006015 134.0
REGS1_k127_5851707_17 - - - - 0.00000000000000000000000008078 112.0
REGS1_k127_5851707_18 - - - - 0.000000000000000000000001456 109.0
REGS1_k127_5851707_2 response regulator receiver - - - 1.248e-241 789.0
REGS1_k127_5851707_3 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 475.0
REGS1_k127_5851707_4 chemotaxis, protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 454.0
REGS1_k127_5851707_5 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008426 289.0
REGS1_k127_5851707_6 helix_turn_helix, Lux Regulon K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001489 276.0
REGS1_k127_5851707_7 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000006407 250.0
REGS1_k127_5851707_8 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000004886 214.0
REGS1_k127_5851707_9 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000000000000000000000000001653 203.0
REGS1_k127_5878078_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1414.0
REGS1_k127_5878078_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0 1079.0
REGS1_k127_5878078_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 552.0
REGS1_k127_5878078_11 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 542.0
REGS1_k127_5878078_12 Oxidoreductase FAD-binding domain protein K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 539.0
REGS1_k127_5878078_13 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 525.0
REGS1_k127_5878078_14 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 480.0
REGS1_k127_5878078_15 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 360.0
REGS1_k127_5878078_16 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 363.0
REGS1_k127_5878078_17 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 342.0
REGS1_k127_5878078_18 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 330.0
REGS1_k127_5878078_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 322.0
REGS1_k127_5878078_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 4.87e-253 786.0
REGS1_k127_5878078_20 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 287.0
REGS1_k127_5878078_21 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001523 261.0
REGS1_k127_5878078_22 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000002998 250.0
REGS1_k127_5878078_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003326 247.0
REGS1_k127_5878078_24 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000001413 242.0
REGS1_k127_5878078_25 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000001656 228.0
REGS1_k127_5878078_26 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000008102 203.0
REGS1_k127_5878078_27 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000002409 172.0
REGS1_k127_5878078_28 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000004539 168.0
REGS1_k127_5878078_3 Aminotransferase class-III K01845 - 5.4.3.8 3.56e-246 763.0
REGS1_k127_5878078_30 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000006871 99.0
REGS1_k127_5878078_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 4.129e-221 687.0
REGS1_k127_5878078_5 Amino acid permease K03294 - - 6.355e-216 678.0
REGS1_k127_5878078_6 PFAM type II and III secretion system protein K02666 - - 2.271e-215 689.0
REGS1_k127_5878078_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 6.81e-205 646.0
REGS1_k127_5878078_8 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 3.004e-194 608.0
REGS1_k127_5878078_9 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 557.0
REGS1_k127_5882842_0 Hsp70 protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1111.0
REGS1_k127_5882842_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.136e-259 803.0
REGS1_k127_5882842_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 397.0
REGS1_k127_5882842_11 PAS domain containing protein K07315,K07675 - 2.7.13.3,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 404.0
REGS1_k127_5882842_12 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 358.0
REGS1_k127_5882842_13 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 355.0
REGS1_k127_5882842_14 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 337.0
REGS1_k127_5882842_15 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 314.0
REGS1_k127_5882842_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009427 247.0
REGS1_k127_5882842_17 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.000000000000000000000000000000000000000001394 165.0
REGS1_k127_5882842_18 pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000001082 146.0
REGS1_k127_5882842_19 Histidine kinase - - - 0.000000000000000000000000000006972 138.0
REGS1_k127_5882842_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 2.381e-204 638.0
REGS1_k127_5882842_21 metallopeptidase activity - - - 0.00000000000000005398 94.0
REGS1_k127_5882842_22 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0004217 42.0
REGS1_k127_5882842_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 3.717e-195 614.0
REGS1_k127_5882842_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 600.0
REGS1_k127_5882842_5 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 591.0
REGS1_k127_5882842_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 573.0
REGS1_k127_5882842_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 529.0
REGS1_k127_5882842_8 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 431.0
REGS1_k127_5882842_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 423.0
REGS1_k127_589751_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 9.077e-308 949.0
REGS1_k127_589751_1 Polyphosphate kinase 2 (PPK2) - - - 1.957e-247 771.0
REGS1_k127_589751_10 Sporulation related domain - - - 0.00000000000000000000000000000001161 134.0
REGS1_k127_589751_11 PFAM Polyphosphate kinase 2 - - - 0.0000000000000117 75.0
REGS1_k127_589751_12 - - - - 0.0000000000001123 74.0
REGS1_k127_589751_13 Domain of unknown function (DUF1768) K09935 - - 0.0000000008143 71.0
REGS1_k127_589751_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 2.764e-240 752.0
REGS1_k127_589751_3 SMART Tetratricopeptide domain protein - - - 1.677e-211 675.0
REGS1_k127_589751_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 351.0
REGS1_k127_589751_5 DSBA-like thioredoxin domain K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000006287 225.0
REGS1_k127_589751_6 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000008839 232.0
REGS1_k127_589751_7 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000000000000003397 203.0
REGS1_k127_589751_8 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000003086 175.0
REGS1_k127_589751_9 Alcohol dehydrogenase zinc-binding domain protein K00001,K00344 - 1.1.1.1,1.6.5.5 0.0000000000000000000000000000000000000008171 149.0
REGS1_k127_5903763_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.995e-226 705.0
REGS1_k127_5903763_1 Carbohydrate-selective porin, OprB family - - - 7.295e-194 615.0
REGS1_k127_5903763_10 - - - - 0.000000000000000000000000000000000000000000000000000000006527 209.0
REGS1_k127_5903763_11 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000003199 117.0
REGS1_k127_5903763_12 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000004783 114.0
REGS1_k127_5903763_13 PFAM Sulfate transporter antisigma-factor antagonist STAS K07122 - - 0.00000000000000002118 87.0
REGS1_k127_5903763_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 608.0
REGS1_k127_5903763_3 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 458.0
REGS1_k127_5903763_4 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 427.0
REGS1_k127_5903763_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 416.0
REGS1_k127_5903763_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 370.0
REGS1_k127_5903763_7 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 359.0
REGS1_k127_5903763_8 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000491 231.0
REGS1_k127_5903763_9 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000004883 225.0
REGS1_k127_5951856_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 2.957e-254 793.0
REGS1_k127_5951856_1 MBOAT, membrane-bound O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 416.0
REGS1_k127_5951856_2 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 422.0
REGS1_k127_5951856_3 Protein of unknown function (DUF459) K09795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 324.0
REGS1_k127_5951856_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000001365 144.0
REGS1_k127_5968347_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1129.0
REGS1_k127_5968347_1 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 4.39e-199 627.0
REGS1_k127_5968347_10 sequence-specific DNA binding - - - 0.000000000000000000000000000009833 120.0
REGS1_k127_5968347_11 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.000000000000000000000004429 102.0
REGS1_k127_5968347_13 protein conserved in bacteria K09919 - - 0.0000001454 56.0
REGS1_k127_5968347_2 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 525.0
REGS1_k127_5968347_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 419.0
REGS1_k127_5968347_4 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 389.0
REGS1_k127_5968347_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 389.0
REGS1_k127_5968347_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 283.0
REGS1_k127_5968347_7 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001333 267.0
REGS1_k127_5968347_8 PFAM Sporulation domain protein - - - 0.0000000000000000000000000000000000000000000000000000001155 203.0
REGS1_k127_5968347_9 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000000001378 122.0
REGS1_k127_598274_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 2.927e-296 912.0
REGS1_k127_598274_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 592.0
REGS1_k127_598274_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 302.0
REGS1_k127_598274_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000365 195.0
REGS1_k127_598274_4 TfoX N-terminal domain K07343 - - 0.0000000000000000000000000000000001306 135.0
REGS1_k127_6046501_0 Spermidine synthase K00797 - 2.5.1.16 2.278e-273 870.0
REGS1_k127_6046501_1 4 iron, 4 sulfur cluster binding K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 546.0
REGS1_k127_6046501_2 - - - - 0.000000000000000000000000000000000000000000000007781 175.0
REGS1_k127_6046501_3 - - - - 0.00000000000000000002095 95.0
REGS1_k127_6046501_4 - - - - 0.000000000000000001925 92.0
REGS1_k127_6046501_5 - - - - 0.00000001946 57.0
REGS1_k127_6135535_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0 1017.0
REGS1_k127_6135535_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.238e-309 961.0
REGS1_k127_6135535_10 PFAM cobalamin synthesis protein P47K K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 416.0
REGS1_k127_6135535_11 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 407.0
REGS1_k127_6135535_12 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 360.0
REGS1_k127_6135535_13 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 339.0
REGS1_k127_6135535_14 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 290.0
REGS1_k127_6135535_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001613 254.0
REGS1_k127_6135535_16 DnaD domain protein - - - 0.0000000000000000000000000000000000000000000008337 180.0
REGS1_k127_6135535_17 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000002081 166.0
REGS1_k127_6135535_18 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000061 148.0
REGS1_k127_6135535_19 - - - - 0.00000000000000000000000000000001279 132.0
REGS1_k127_6135535_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.873e-301 927.0
REGS1_k127_6135535_20 - - - - 0.00000000000000000000000000003786 122.0
REGS1_k127_6135535_21 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000002188 113.0
REGS1_k127_6135535_22 - - - - 0.000000000000000000000002029 108.0
REGS1_k127_6135535_23 - - - - 0.0000000000000007332 81.0
REGS1_k127_6135535_3 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 3.02e-222 693.0
REGS1_k127_6135535_4 Phage tail sheath protein subtilisin-like domain K06907 - - 3.073e-212 670.0
REGS1_k127_6135535_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 6.111e-208 649.0
REGS1_k127_6135535_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 1.573e-206 646.0
REGS1_k127_6135535_7 PFAM AIR synthase related protein domain protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 575.0
REGS1_k127_6135535_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 540.0
REGS1_k127_6135535_9 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 454.0
REGS1_k127_6147247_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1037.0
REGS1_k127_6147247_1 PFAM cytochrome c biogenesis protein transmembrane region - - - 4.05e-268 834.0
REGS1_k127_6147247_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001083 265.0
REGS1_k127_6147247_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003569 256.0
REGS1_k127_6147247_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000001628 250.0
REGS1_k127_6147247_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000001964 163.0
REGS1_k127_6147247_14 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000001888 123.0
REGS1_k127_6147247_2 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 6.903e-253 788.0
REGS1_k127_6147247_3 NADH flavin oxidoreductase NADH oxidase K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 587.0
REGS1_k127_6147247_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 498.0
REGS1_k127_6147247_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 306.0
REGS1_k127_6147247_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 305.0
REGS1_k127_6147247_7 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005806 283.0
REGS1_k127_6147247_8 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005615 276.0
REGS1_k127_6147247_9 methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009405 271.0
REGS1_k127_6169554_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 3.081e-239 743.0
REGS1_k127_6169554_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 608.0
REGS1_k127_6169554_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 535.0
REGS1_k127_6169554_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 472.0
REGS1_k127_6169554_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 349.0
REGS1_k127_6169554_5 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000002492 248.0
REGS1_k127_6169554_6 PFAM HopJ type III effector protein - - - 0.000000000000000000000000000000000000000000000005149 174.0
REGS1_k127_6169554_7 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000001532 134.0
REGS1_k127_6169554_8 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000001678 130.0
REGS1_k127_6190914_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 6.321e-314 972.0
REGS1_k127_6190914_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.031e-268 836.0
REGS1_k127_6190914_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 2.417e-218 681.0
REGS1_k127_6190914_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006726 273.0
REGS1_k127_6190914_4 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000000007231 219.0
REGS1_k127_6190914_5 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000006504 158.0
REGS1_k127_6190914_6 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000002195 132.0
REGS1_k127_6300281_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1522.0
REGS1_k127_6300281_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 565.0
REGS1_k127_6300281_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000001845 198.0
REGS1_k127_6300281_12 oxygen carrier activity K07216 - - 0.000000000000000000000000000000000000000000000001313 179.0
REGS1_k127_6300281_13 Cold shock protein K03704 - - 0.00000000000000000000000000000001941 127.0
REGS1_k127_6300281_14 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000000000292 115.0
REGS1_k127_6300281_15 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000002121 100.0
REGS1_k127_6300281_16 - - - - 0.000000000000000000257 89.0
REGS1_k127_6300281_17 - - - - 0.00000000000000001193 85.0
REGS1_k127_6300281_18 - - - - 0.000000000002644 72.0
REGS1_k127_6300281_19 YqjK-like protein - - - 0.0001734 48.0
REGS1_k127_6300281_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 508.0
REGS1_k127_6300281_3 LysM domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 485.0
REGS1_k127_6300281_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 475.0
REGS1_k127_6300281_5 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 412.0
REGS1_k127_6300281_6 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 370.0
REGS1_k127_6300281_7 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 283.0
REGS1_k127_6300281_8 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002448 250.0
REGS1_k127_6300281_9 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003059 248.0
REGS1_k127_6319370_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 608.0
REGS1_k127_6319370_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 528.0
REGS1_k127_6319370_2 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 301.0
REGS1_k127_6319370_3 Rhodanese Homology Domain - - - 0.000000000000000000005169 93.0
REGS1_k127_6432352_0 Belongs to the peptidase M16 family K07263 - - 2.122e-197 624.0
REGS1_k127_6432352_1 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 601.0
REGS1_k127_6432352_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 512.0
REGS1_k127_6432352_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009584 278.0
REGS1_k127_6432352_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000008162 257.0
REGS1_k127_6432352_5 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001151 246.0
REGS1_k127_6432352_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000002358 176.0
REGS1_k127_6523550_0 Sugar (and other) transporter - - - 8.616e-234 734.0
REGS1_k127_6523550_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 502.0
REGS1_k127_6523550_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 499.0
REGS1_k127_6523550_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 418.0
REGS1_k127_6523550_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 293.0
REGS1_k127_6523550_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000001228 218.0
REGS1_k127_6523550_6 Pfam:DUF1311 - - - 0.00000007014 63.0
REGS1_k127_652413_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1451.0
REGS1_k127_652413_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1300.0
REGS1_k127_652413_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 399.0
REGS1_k127_652413_11 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 368.0
REGS1_k127_652413_12 PFAM import inner membrane translocase subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 344.0
REGS1_k127_652413_13 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000000000000000000000000000000004884 229.0
REGS1_k127_652413_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000002021 214.0
REGS1_k127_652413_15 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000005185 190.0
REGS1_k127_652413_16 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000000000000000000002609 158.0
REGS1_k127_652413_17 Putative quorum-sensing-regulated virulence factor K09954 - - 0.0000000000000000000000000000000000002042 140.0
REGS1_k127_652413_18 - - - - 0.0000000000007622 81.0
REGS1_k127_652413_2 COG1404 Subtilisin-like serine proteases - - - 0.0 1080.0
REGS1_k127_652413_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.72e-313 967.0
REGS1_k127_652413_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 5.832e-234 730.0
REGS1_k127_652413_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.956e-231 717.0
REGS1_k127_652413_6 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 5.808e-194 617.0
REGS1_k127_652413_7 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 611.0
REGS1_k127_652413_8 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 492.0
REGS1_k127_652413_9 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 449.0
REGS1_k127_6614089_0 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 1.112e-272 841.0
REGS1_k127_6614089_1 PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 375.0
REGS1_k127_6614089_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 327.0
REGS1_k127_6614089_3 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004609 252.0
REGS1_k127_6782700_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1569.0
REGS1_k127_6782700_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.447e-299 931.0
REGS1_k127_6782700_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 443.0
REGS1_k127_6782700_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 381.0
REGS1_k127_6782700_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001471 243.0
REGS1_k127_6782700_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000001515 61.0
REGS1_k127_6802995_0 B3/4 domain K01890 - 6.1.1.20 0.0 1205.0
REGS1_k127_6802995_1 Threonyl and Alanyl tRNA synthetase second additional domain K01868 - 6.1.1.3 0.0 1101.0
REGS1_k127_6802995_10 Dihydroneopterin aldolase - - - 0.000000000000000000000000000000000000002141 154.0
REGS1_k127_6802995_11 related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000001599 149.0
REGS1_k127_6802995_12 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000007957 144.0
REGS1_k127_6802995_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000000000001971 132.0
REGS1_k127_6802995_14 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000004672 113.0
REGS1_k127_6802995_16 dehydrogenase - - - 0.000003517 51.0
REGS1_k127_6802995_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 4.148e-200 626.0
REGS1_k127_6802995_3 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 348.0
REGS1_k127_6802995_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 314.0
REGS1_k127_6802995_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000000297 209.0
REGS1_k127_6802995_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000000001282 188.0
REGS1_k127_6802995_7 peptidase - - - 0.0000000000000000000000000000000000000000000000001928 188.0
REGS1_k127_6802995_8 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000000000000000000000001447 170.0
REGS1_k127_6802995_9 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000005703 158.0
REGS1_k127_6818232_0 Peptidase family M48 - - - 3.709e-248 773.0
REGS1_k127_6818232_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 2.005e-231 718.0
REGS1_k127_6818232_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000000000001305 228.0
REGS1_k127_6818232_3 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000000007774 142.0
REGS1_k127_6857354_0 fibronectin type III domain protein K06882 - - 0.0 1269.0
REGS1_k127_6857354_1 DNA ligase K01971 - 6.5.1.1 1.187e-291 918.0
REGS1_k127_6857354_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 380.0
REGS1_k127_6857354_11 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 346.0
REGS1_k127_6857354_12 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 323.0
REGS1_k127_6857354_13 SMART Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 300.0
REGS1_k127_6857354_14 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 305.0
REGS1_k127_6857354_15 hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 302.0
REGS1_k127_6857354_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 310.0
REGS1_k127_6857354_17 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 295.0
REGS1_k127_6857354_18 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006568 268.0
REGS1_k127_6857354_19 phosphatase homologous to the C-terminal domain of histone macroH2A1 - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001179 216.0
REGS1_k127_6857354_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 1.341e-276 865.0
REGS1_k127_6857354_20 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000000000000004966 172.0
REGS1_k127_6857354_21 PFAM KaiB domain K08481 - - 0.000000000000000000000000000021 123.0
REGS1_k127_6857354_22 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000002285 108.0
REGS1_k127_6857354_3 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 5.469e-230 731.0
REGS1_k127_6857354_4 flavoprotein, PP_4765 family K07007 - - 4.59e-218 682.0
REGS1_k127_6857354_5 Pfam:KaiC K08482 - - 1.342e-213 678.0
REGS1_k127_6857354_6 Putative diguanylate phosphodiesterase - - - 1.819e-210 676.0
REGS1_k127_6857354_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 629.0
REGS1_k127_6857354_8 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 583.0
REGS1_k127_6857354_9 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 422.0
REGS1_k127_6860746_0 Protein of unknown function, DUF255 K06888 - - 1.896e-282 886.0
REGS1_k127_6860746_1 cellulose synthase K00694 - 2.4.1.12 2.267e-275 875.0
REGS1_k127_6860746_10 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 479.0
REGS1_k127_6860746_11 cellulose synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 454.0
REGS1_k127_6860746_12 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 426.0
REGS1_k127_6860746_13 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 402.0
REGS1_k127_6860746_14 cellulose synthase operon C domain protein K20543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 394.0
REGS1_k127_6860746_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 350.0
REGS1_k127_6860746_16 Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 343.0
REGS1_k127_6860746_17 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 332.0
REGS1_k127_6860746_18 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 326.0
REGS1_k127_6860746_19 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 308.0
REGS1_k127_6860746_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.497e-254 789.0
REGS1_k127_6860746_20 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000227 256.0
REGS1_k127_6860746_21 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002544 249.0
REGS1_k127_6860746_22 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003428 241.0
REGS1_k127_6860746_23 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001328 261.0
REGS1_k127_6860746_24 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000005812 243.0
REGS1_k127_6860746_25 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000008378 249.0
REGS1_k127_6860746_26 Belongs to the MsrB Met sulfoxide reductase family K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000253 228.0
REGS1_k127_6860746_27 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000005664 209.0
REGS1_k127_6860746_28 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000000001813 203.0
REGS1_k127_6860746_29 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000002913 190.0
REGS1_k127_6860746_3 Large family of predicted nucleotide-binding domains K07175 - - 3.558e-253 787.0
REGS1_k127_6860746_30 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000005584 145.0
REGS1_k127_6860746_31 YCII-related domain K09780 - - 0.000000000000000000000000000000000001277 140.0
REGS1_k127_6860746_32 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000007671 122.0
REGS1_k127_6860746_33 Belongs to the ompA family K03286 - - 0.0000000000000000000000000001422 123.0
REGS1_k127_6860746_34 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000002977 112.0
REGS1_k127_6860746_35 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000009833 93.0
REGS1_k127_6860746_37 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.000276 53.0
REGS1_k127_6860746_4 DAHP synthetase I family K03856 - 2.5.1.54 1.284e-213 667.0
REGS1_k127_6860746_5 RmuC family K09760 - - 1.422e-208 654.0
REGS1_k127_6860746_6 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 599.0
REGS1_k127_6860746_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 539.0
REGS1_k127_6860746_8 cellulose synthase K20541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 563.0
REGS1_k127_6860746_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 503.0
REGS1_k127_6939341_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.024e-245 764.0
REGS1_k127_6939341_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 2.081e-244 762.0
REGS1_k127_6939341_2 Putative diguanylate phosphodiesterase - - - 1.569e-240 758.0
REGS1_k127_6939341_3 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 613.0
REGS1_k127_6939341_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 466.0
REGS1_k127_6939341_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 417.0
REGS1_k127_6939341_6 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 313.0
REGS1_k127_6939341_7 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 297.0
REGS1_k127_6939341_8 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004346 253.0
REGS1_k127_6939341_9 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000002725 215.0
REGS1_k127_69468_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 512.0
REGS1_k127_69468_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 387.0
REGS1_k127_69468_2 Super-infection exclusion protein B - - - 0.00000000000000002977 87.0
REGS1_k127_7084048_0 PFAM glycosyl transferase family 39 - - - 5.362e-209 678.0
REGS1_k127_7084048_1 Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 469.0
REGS1_k127_7084048_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 319.0
REGS1_k127_7084048_3 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000003789 176.0
REGS1_k127_7084048_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000001503 132.0
REGS1_k127_712810_0 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 317.0
REGS1_k127_712810_1 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 304.0
REGS1_k127_712810_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000003008 223.0
REGS1_k127_712810_3 - - - - 0.000000000000000000000000000000000000000000000002974 175.0
REGS1_k127_712810_4 - - - - 0.000000000000000000000000000000000000004936 150.0
REGS1_k127_712810_5 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000005665 55.0
REGS1_k127_7151712_0 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 6.755e-310 967.0
REGS1_k127_7151712_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.7e-275 852.0
REGS1_k127_7151712_10 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000000000000000005055 198.0
REGS1_k127_7151712_11 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000006254 165.0
REGS1_k127_7151712_12 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000001295 168.0
REGS1_k127_7151712_13 Sporulation related domain K03749 - - 0.0000000000000000000000000000000000006063 147.0
REGS1_k127_7151712_14 Transcriptional regulator - - - 0.00000000000000006566 88.0
REGS1_k127_7151712_15 Domain of unknown function (DUF1963) - - - 0.0000006194 62.0
REGS1_k127_7151712_2 Outer membrane lipoprotein-sorting protein K07003 - - 1.074e-235 752.0
REGS1_k127_7151712_3 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 7.872e-220 695.0
REGS1_k127_7151712_4 Protein of unknown function DUF262 - - - 1.618e-218 698.0
REGS1_k127_7151712_5 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 576.0
REGS1_k127_7151712_6 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 551.0
REGS1_k127_7151712_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 492.0
REGS1_k127_7151712_8 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 337.0
REGS1_k127_7151712_9 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004009 251.0
REGS1_k127_7236740_0 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009503 250.0
REGS1_k127_7236740_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005048 246.0
REGS1_k127_7236740_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000118 205.0
REGS1_k127_7290639_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.784e-292 902.0
REGS1_k127_7290639_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 505.0
REGS1_k127_7290639_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000005173 209.0
REGS1_k127_7290639_3 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000001324 189.0
REGS1_k127_7290639_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K12976,K16079 - - 0.0000000000000000002008 97.0
REGS1_k127_7302363_0 CoA-binding domain protein K09181 - - 0.0 1481.0
REGS1_k127_7302363_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1070.0
REGS1_k127_7302363_10 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 504.0
REGS1_k127_7302363_11 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 503.0
REGS1_k127_7302363_12 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 484.0
REGS1_k127_7302363_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 479.0
REGS1_k127_7302363_14 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 434.0
REGS1_k127_7302363_15 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 432.0
REGS1_k127_7302363_16 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 410.0
REGS1_k127_7302363_17 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 402.0
REGS1_k127_7302363_18 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 397.0
REGS1_k127_7302363_19 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 379.0
REGS1_k127_7302363_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.519e-265 827.0
REGS1_k127_7302363_20 PFAM GumN family protein K09973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 371.0
REGS1_k127_7302363_21 COG1994 Zn-dependent proteases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 351.0
REGS1_k127_7302363_22 membrane-anchored protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 349.0
REGS1_k127_7302363_23 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 317.0
REGS1_k127_7302363_24 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 307.0
REGS1_k127_7302363_25 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 288.0
REGS1_k127_7302363_26 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003249 285.0
REGS1_k127_7302363_27 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001423 278.0
REGS1_k127_7302363_28 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000001773 258.0
REGS1_k127_7302363_29 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.0000000000000000000000000000000000000000000000000000000000001087 221.0
REGS1_k127_7302363_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.509e-235 749.0
REGS1_k127_7302363_30 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000000000000001904 190.0
REGS1_k127_7302363_31 Spore Coat Protein U domain - - - 0.00000000000000000000000000000000000001878 155.0
REGS1_k127_7302363_32 - - - - 0.0000000000000000000000000000000376 131.0
REGS1_k127_7302363_33 GTP-binding protein TypA K06207 - - 0.00000002225 55.0
REGS1_k127_7302363_34 - - - - 0.000004436 49.0
REGS1_k127_7302363_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 3.456e-232 722.0
REGS1_k127_7302363_5 Outer membrane usher protein K07347 - - 4.261e-226 725.0
REGS1_k127_7302363_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 604.0
REGS1_k127_7302363_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 588.0
REGS1_k127_7302363_8 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 522.0
REGS1_k127_7302363_9 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 509.0
REGS1_k127_7419651_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1663.0
REGS1_k127_7419651_1 Insulinase (Peptidase family M16) K07263 - - 0.0 1063.0
REGS1_k127_7419651_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 544.0
REGS1_k127_7419651_4 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005607 238.0
REGS1_k127_7419651_5 - - - - 0.000000000000000000000000000000000005064 141.0
REGS1_k127_7419651_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000009442 136.0
REGS1_k127_7419651_8 - - - - 0.000000000000000000000004146 106.0
REGS1_k127_7438461_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.165e-246 766.0
REGS1_k127_7438461_1 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 2.716e-223 694.0
REGS1_k127_7438461_2 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 449.0
REGS1_k127_7438461_3 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 363.0
REGS1_k127_7438461_4 MltA-interacting MipA family protein K07274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 334.0
REGS1_k127_7438461_5 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000182 249.0
REGS1_k127_7438461_6 SpoIIAA-like - - - 0.000000000000000000000000000000000000000000000000001299 186.0
REGS1_k127_748866_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.316e-308 949.0
REGS1_k127_748866_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 6.435e-235 732.0
REGS1_k127_748866_10 ATP synthase I chain K02116 - - 0.00003438 51.0
REGS1_k127_748866_11 OmpA-like transmembrane domain K03286 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 - 0.00003488 53.0
REGS1_k127_748866_2 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 494.0
REGS1_k127_748866_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 448.0
REGS1_k127_748866_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 419.0
REGS1_k127_748866_5 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 319.0
REGS1_k127_748866_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000002697 226.0
REGS1_k127_748866_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000006131 209.0
REGS1_k127_748866_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000002067 156.0
REGS1_k127_748866_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000009139 139.0
REGS1_k127_7499344_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 471.0
REGS1_k127_7499344_1 pteridine-dependent deoxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 384.0
REGS1_k127_7499344_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 284.0
REGS1_k127_7499344_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000001897 217.0
REGS1_k127_7499344_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000003739 145.0
REGS1_k127_7499344_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000004037 52.0
REGS1_k127_7580512_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 9.512e-195 617.0
REGS1_k127_7580512_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 515.0
REGS1_k127_7580512_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 415.0
REGS1_k127_7580512_3 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000002232 218.0
REGS1_k127_7580512_4 RecX family K03565 - - 0.00000000000000000000000000000000000000000000000000000000002444 213.0
REGS1_k127_7580512_5 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.0000000003083 68.0
REGS1_k127_7612495_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2128.0
REGS1_k127_7612495_1 Two component signalling adaptor domain - - - 0.0 1117.0
REGS1_k127_7612495_10 synthase K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000441 287.0
REGS1_k127_7612495_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005614 282.0
REGS1_k127_7612495_12 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006801 261.0
REGS1_k127_7612495_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000006657 252.0
REGS1_k127_7612495_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000001537 244.0
REGS1_k127_7612495_15 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005483 241.0
REGS1_k127_7612495_16 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001424 231.0
REGS1_k127_7612495_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000003286 211.0
REGS1_k127_7612495_18 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000000000000000000000000000000000000003367 216.0
REGS1_k127_7612495_19 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.0000000000000000000000000000000000000000000000000000007256 195.0
REGS1_k127_7612495_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0 1109.0
REGS1_k127_7612495_20 Protein of unknown function (DUF2937) - - - 0.000000000000000000000000000000000000000000000000000001071 197.0
REGS1_k127_7612495_21 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000006803 172.0
REGS1_k127_7612495_22 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000006432 141.0
REGS1_k127_7612495_23 Cytochrome c, class I K08738 - - 0.0000000000000000000000000000000004146 139.0
REGS1_k127_7612495_25 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000001074 114.0
REGS1_k127_7612495_27 Protein of unknown function (DUF2934) - - - 0.00000000000000001895 88.0
REGS1_k127_7612495_28 - - - - 0.00000000006677 70.0
REGS1_k127_7612495_29 Domain of unknown function (DUF4124) - - - 0.00006877 53.0
REGS1_k127_7612495_3 Cytochrome c1 - - - 2.477e-254 802.0
REGS1_k127_7612495_4 4 iron, 4 sulfur cluster binding - - - 4.334e-233 732.0
REGS1_k127_7612495_5 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 569.0
REGS1_k127_7612495_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 481.0
REGS1_k127_7612495_7 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 364.0
REGS1_k127_7612495_8 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 357.0
REGS1_k127_7612495_9 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 354.0
REGS1_k127_7645584_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1517.0
REGS1_k127_7645584_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 509.0
REGS1_k127_7645584_2 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000003693 168.0
REGS1_k127_7645584_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000000000000002087 161.0
REGS1_k127_7645584_4 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000177 151.0
REGS1_k127_7645584_5 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000006612 76.0
REGS1_k127_7655139_0 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 0.0 1055.0
REGS1_k127_7655139_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.049e-309 963.0
REGS1_k127_7655139_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 434.0
REGS1_k127_7655139_3 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 328.0
REGS1_k127_7655139_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 289.0
REGS1_k127_7655139_5 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000006 233.0
REGS1_k127_7655139_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000129 82.0
REGS1_k127_7672248_0 ATPases associated with a variety of cellular activities - - - 0.0 1382.0
REGS1_k127_7672248_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 5.328e-205 644.0
REGS1_k127_7672248_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 596.0
REGS1_k127_7672248_3 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 614.0
REGS1_k127_7672248_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 499.0
REGS1_k127_7672248_5 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 391.0
REGS1_k127_7672248_6 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 355.0
REGS1_k127_7672248_7 Zinc-finger domain - - - 0.00000000000000000000000001984 111.0
REGS1_k127_7672248_8 Protein tyrosine kinase - - - 0.00005194 57.0
REGS1_k127_7672248_9 Carboxypeptidase regulatory-like domain - - - 0.0006183 48.0
REGS1_k127_7672798_0 PLD-like domain - - - 1.595e-285 887.0
REGS1_k127_7672798_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 458.0
REGS1_k127_7672798_10 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000004278 157.0
REGS1_k127_7672798_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000004799 124.0
REGS1_k127_7672798_12 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000001269 121.0
REGS1_k127_7672798_13 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000003081 82.0
REGS1_k127_7672798_14 Ribonuclease P K03536 - 3.1.26.5 0.00000000000000008165 85.0
REGS1_k127_7672798_15 - - - - 0.00000000001468 72.0
REGS1_k127_7672798_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 295.0
REGS1_k127_7672798_3 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009386 288.0
REGS1_k127_7672798_4 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001162 265.0
REGS1_k127_7672798_5 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001897 241.0
REGS1_k127_7672798_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000005602 229.0
REGS1_k127_7672798_7 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000009965 222.0
REGS1_k127_7672798_8 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.0000000000000000000000000000000000000000000000000000002096 199.0
REGS1_k127_7672798_9 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000009059 192.0
REGS1_k127_7701659_0 Histidine kinase K11617 - 2.7.13.3 2.788e-223 706.0
REGS1_k127_7701659_1 Ankyrin repeats (3 copies) - - - 0.000000000000000000000000000000000000000949 161.0
REGS1_k127_7701659_2 - - - - 0.0000000000000000000000000000000000001042 149.0
REGS1_k127_7701659_3 ankyrin repeat protein - - - 0.0000000000000000000000000000001013 136.0
REGS1_k127_7701659_4 Ankyrin repeats (many copies) - - - 0.00000000000000000000000002963 117.0
REGS1_k127_7701659_5 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000001404 108.0
REGS1_k127_7701659_6 - - - - 0.0008199 48.0
REGS1_k127_7704159_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 609.0
REGS1_k127_7704159_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 386.0
REGS1_k127_7704159_10 chitinase - - - 0.00000000001516 78.0
REGS1_k127_7704159_11 - - - - 0.00000000001862 74.0
REGS1_k127_7704159_12 - - - - 0.00001868 49.0
REGS1_k127_7704159_13 Bacterial Ig-like domain 2 - - - 0.0005125 48.0
REGS1_k127_7704159_14 - - - - 0.0005841 51.0
REGS1_k127_7704159_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001321 254.0
REGS1_k127_7704159_3 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
REGS1_k127_7704159_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000004129 227.0
REGS1_k127_7704159_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000003389 220.0
REGS1_k127_7704159_6 - - - - 0.0000000000000000000000000000000000000005825 157.0
REGS1_k127_7704159_7 - - - - 0.00000000000000000000000002597 111.0
REGS1_k127_7704159_8 SseB protein N-terminal domain - - - 0.0000000000000000000001781 101.0
REGS1_k127_7704159_9 - - - - 0.0000000000000007341 85.0
REGS1_k127_7730213_0 RNB K01147 - 3.1.13.1 7.861e-302 937.0
REGS1_k127_7730213_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.723e-233 725.0
REGS1_k127_7730213_10 Cytochrome C oxidase, cbb3-type, subunit III K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000001221 119.0
REGS1_k127_7730213_11 Probable zinc-ribbon domain - - - 0.00000000000000000000000001943 115.0
REGS1_k127_7730213_12 EF-hand domain pair - - - 0.000000000000000000008206 101.0
REGS1_k127_7730213_2 von Willebrand factor (vWF) type A domain - - - 4.104e-197 636.0
REGS1_k127_7730213_3 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 578.0
REGS1_k127_7730213_4 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 489.0
REGS1_k127_7730213_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 415.0
REGS1_k127_7730213_6 Predicted nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 398.0
REGS1_k127_7730213_7 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 354.0
REGS1_k127_7730213_8 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 305.0
REGS1_k127_7730213_9 - - - - 0.000000000000000000000000000000000000000000000000001463 190.0
REGS1_k127_7789971_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 1.409e-217 680.0
REGS1_k127_7789971_1 Soluble lytic murein transglycosylase L domain K08309 - - 5.273e-214 685.0
REGS1_k127_7789971_10 - - - - 0.0000000000000000000003506 101.0
REGS1_k127_7789971_11 Polymer-forming cytoskeletal - - - 0.00000089 51.0
REGS1_k127_7789971_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 580.0
REGS1_k127_7789971_3 PFAM ABC transporter related K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 580.0
REGS1_k127_7789971_4 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 324.0
REGS1_k127_7789971_5 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 291.0
REGS1_k127_7789971_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001877 269.0
REGS1_k127_7789971_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000000000459 230.0
REGS1_k127_7789971_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005575 236.0
REGS1_k127_7789971_9 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000006769 181.0
REGS1_k127_7811200_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1572.0
REGS1_k127_7811200_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 3.985e-204 643.0
REGS1_k127_7811200_2 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
REGS1_k127_7811200_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 509.0
REGS1_k127_7811200_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 451.0
REGS1_k127_7811200_5 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 413.0
REGS1_k127_7811200_6 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 408.0
REGS1_k127_7811200_7 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000123 213.0
REGS1_k127_7811200_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000002623 205.0
REGS1_k127_7811200_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000004059 122.0
REGS1_k127_7851994_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 4.966e-222 695.0
REGS1_k127_7851994_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 7.877e-220 685.0
REGS1_k127_7851994_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 328.0
REGS1_k127_7851994_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 322.0
REGS1_k127_7851994_12 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 299.0
REGS1_k127_7851994_13 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007922 266.0
REGS1_k127_7851994_14 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000001668 191.0
REGS1_k127_7851994_15 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000000008197 177.0
REGS1_k127_7851994_16 - - - - 0.00000000000000000000000000000000000006109 151.0
REGS1_k127_7851994_17 ABC transporter transmembrane region K11004 - - 0.0000000000000000000006833 95.0
REGS1_k127_7851994_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 587.0
REGS1_k127_7851994_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 565.0
REGS1_k127_7851994_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 541.0
REGS1_k127_7851994_5 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 522.0
REGS1_k127_7851994_6 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 462.0
REGS1_k127_7851994_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 434.0
REGS1_k127_7851994_8 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 377.0
REGS1_k127_7851994_9 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 362.0
REGS1_k127_7994381_0 glutamate synthase, alpha subunit domain protein K00265 - 1.4.1.13,1.4.1.14 0.0 2251.0
REGS1_k127_7994381_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1062.0
REGS1_k127_7994381_10 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 432.0
REGS1_k127_7994381_11 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 409.0
REGS1_k127_7994381_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 398.0
REGS1_k127_7994381_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 389.0
REGS1_k127_7994381_14 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 385.0
REGS1_k127_7994381_15 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 387.0
REGS1_k127_7994381_16 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 324.0
REGS1_k127_7994381_17 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 294.0
REGS1_k127_7994381_18 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003121 271.0
REGS1_k127_7994381_19 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008166 257.0
REGS1_k127_7994381_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1045.0
REGS1_k127_7994381_20 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000001398 212.0
REGS1_k127_7994381_21 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000000000000000003482 179.0
REGS1_k127_7994381_22 PFAM cytochrome c class I K08738 - - 0.00000000000000000000000000000000000000000000009751 171.0
REGS1_k127_7994381_23 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000001266 160.0
REGS1_k127_7994381_24 PFAM cytochrome c class I K08738 - - 0.00000000000000000000000000000001391 131.0
REGS1_k127_7994381_3 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.804e-283 874.0
REGS1_k127_7994381_4 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.806e-263 830.0
REGS1_k127_7994381_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 2.194e-218 681.0
REGS1_k127_7994381_6 Cytochrome b(N-terminal)/b6/petB K00412 - - 3.498e-218 682.0
REGS1_k127_7994381_7 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 1.186e-203 646.0
REGS1_k127_7994381_8 Phosphotransferase enzyme family K07102 - 2.7.1.221 4.811e-194 610.0
REGS1_k127_7994381_9 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 490.0
REGS1_k127_8029585_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 360.0
REGS1_k127_8029585_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001305 255.0
REGS1_k127_8029585_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000009223 195.0
REGS1_k127_8081689_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1462.0
REGS1_k127_8081689_1 AAA ATPase domain - - - 5.936e-300 963.0
REGS1_k127_8081689_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 3.05e-226 703.0
REGS1_k127_8081689_3 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 496.0
REGS1_k127_8081689_5 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000718 126.0
REGS1_k127_8081689_6 ATP diphosphatase activity - - - 0.00000000000001571 85.0
REGS1_k127_8081689_7 Transposase - - - 0.0000005713 53.0
REGS1_k127_8117619_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 578.0
REGS1_k127_8117619_1 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 308.0
REGS1_k127_8117619_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000002162 101.0
REGS1_k127_8117619_3 - - - - 0.00000000003867 63.0
REGS1_k127_8170517_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1262.0
REGS1_k127_8170517_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1234.0
REGS1_k127_8170517_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004706 246.0
REGS1_k127_8170517_11 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000000000000001216 209.0
REGS1_k127_8170517_12 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000002806 192.0
REGS1_k127_8170517_13 Histidine kinase K11617 - 2.7.13.3 0.000000000000000000000000000000003002 145.0
REGS1_k127_8170517_14 antisigma factor binding K04749 - - 0.000000000000000000000000001919 115.0
REGS1_k127_8170517_15 Histidine kinase-like ATPase domain - - - 0.00000000000000002604 96.0
REGS1_k127_8170517_16 chemotaxis - - - 0.00000009499 64.0
REGS1_k127_8170517_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0 1056.0
REGS1_k127_8170517_3 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 4.096e-317 992.0
REGS1_k127_8170517_4 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 462.0
REGS1_k127_8170517_5 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 422.0
REGS1_k127_8170517_6 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 416.0
REGS1_k127_8170517_7 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 411.0
REGS1_k127_8170517_8 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 344.0
REGS1_k127_8170517_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 312.0
REGS1_k127_8282011_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1137.0
REGS1_k127_8282011_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1069.0
REGS1_k127_8282011_10 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000000000008356 133.0
REGS1_k127_8282011_11 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000007128 94.0
REGS1_k127_8282011_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 604.0
REGS1_k127_8282011_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 476.0
REGS1_k127_8282011_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 488.0
REGS1_k127_8282011_5 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 445.0
REGS1_k127_8282011_6 Domain of unknown function (DUF3391) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 312.0
REGS1_k127_8282011_7 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000338 240.0
REGS1_k127_8282011_8 TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000000000001453 162.0
REGS1_k127_8282011_9 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000000000000001939 148.0
REGS1_k127_8286347_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 2091.0
REGS1_k127_8286347_1 Ammonium Transporter Family K03320 - - 1.473e-279 864.0
REGS1_k127_8286347_11 Protein of unknown function (DUF2288) - - - 0.0000000000000000000000000000000000006682 142.0
REGS1_k127_8286347_12 Membrane fusogenic activity K09806 - - 0.00000000000000000000003536 100.0
REGS1_k127_8286347_13 - - - - 0.0000000000000001439 95.0
REGS1_k127_8286347_14 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000402 49.0
REGS1_k127_8286347_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 5.521e-271 839.0
REGS1_k127_8286347_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 602.0
REGS1_k127_8286347_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 495.0
REGS1_k127_8286347_5 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 315.0
REGS1_k127_8286347_6 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 257.0
REGS1_k127_8286347_7 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000004734 234.0
REGS1_k127_8286347_8 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003179 214.0
REGS1_k127_8286347_9 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000003738 203.0
REGS1_k127_8356700_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1024.0
REGS1_k127_8356700_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.173e-297 925.0
REGS1_k127_8356700_10 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 460.0
REGS1_k127_8356700_11 P-loop ATPase protein family K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 427.0
REGS1_k127_8356700_12 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 425.0
REGS1_k127_8356700_13 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 367.0
REGS1_k127_8356700_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 362.0
REGS1_k127_8356700_15 secretion protein HlyD family K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 332.0
REGS1_k127_8356700_16 transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 313.0
REGS1_k127_8356700_17 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 302.0
REGS1_k127_8356700_18 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001591 280.0
REGS1_k127_8356700_19 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006374 279.0
REGS1_k127_8356700_2 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 3.982e-292 910.0
REGS1_k127_8356700_20 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 274.0
REGS1_k127_8356700_21 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000006101 228.0
REGS1_k127_8356700_22 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000004855 230.0
REGS1_k127_8356700_23 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000001212 208.0
REGS1_k127_8356700_24 NusG domain II - - - 0.000000000000000000000000000000000000000000000000003018 186.0
REGS1_k127_8356700_25 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000000000000000000005138 187.0
REGS1_k127_8356700_26 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000007299 172.0
REGS1_k127_8356700_27 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000003176 156.0
REGS1_k127_8356700_3 4Fe-4S single cluster domain - - - 3.329e-242 759.0
REGS1_k127_8356700_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.235e-227 712.0
REGS1_k127_8356700_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 8.026e-201 635.0
REGS1_k127_8356700_6 Major Facilitator Superfamily K08227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 521.0
REGS1_k127_8356700_7 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 484.0
REGS1_k127_8356700_8 Major facilitator superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 486.0
REGS1_k127_8356700_9 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 453.0
REGS1_k127_8360882_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 5.678e-247 778.0
REGS1_k127_8360882_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 6.57e-208 661.0
REGS1_k127_8360882_10 Protein of unknown function (DUF2799) - - - 0.000000000000000000000000004626 124.0
REGS1_k127_8360882_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 518.0
REGS1_k127_8360882_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 354.0
REGS1_k127_8360882_4 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 332.0
REGS1_k127_8360882_5 Belongs to the WrbA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 319.0
REGS1_k127_8360882_6 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 300.0
REGS1_k127_8360882_7 Acyl carrier protein phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003513 272.0
REGS1_k127_8360882_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002186 267.0
REGS1_k127_8360882_9 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000002578 224.0
REGS1_k127_8364070_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 583.0
REGS1_k127_8364070_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 369.0
REGS1_k127_8364070_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 361.0
REGS1_k127_8364070_3 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 353.0
REGS1_k127_8364070_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000005222 207.0
REGS1_k127_8364070_5 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000003427 192.0
REGS1_k127_8364070_6 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000000000000000000046 187.0
REGS1_k127_8364070_7 OmpA family K03640 - - 0.000000000000000000000000000000000000000000000000001458 187.0
REGS1_k127_8364070_8 TolA C-terminal K03646 - - 0.000000000000000000000000000000000000000002767 166.0
REGS1_k127_8435281_0 SMC domain protein - - - 0.0 1474.0
REGS1_k127_8435281_1 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 9.138e-282 870.0
REGS1_k127_8435281_10 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 294.0
REGS1_k127_8435281_11 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000148 272.0
REGS1_k127_8435281_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000006888 256.0
REGS1_k127_8435281_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000001667 157.0
REGS1_k127_8435281_15 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000434 109.0
REGS1_k127_8435281_2 DHH family K07462 - - 7.091e-270 839.0
REGS1_k127_8435281_3 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 2.932e-233 726.0
REGS1_k127_8435281_4 - - - - 7.158e-206 649.0
REGS1_k127_8435281_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 599.0
REGS1_k127_8435281_6 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 547.0
REGS1_k127_8435281_7 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 510.0
REGS1_k127_8435281_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 381.0
REGS1_k127_8435281_9 Formate acetyltransferase K00656 - 2.3.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 372.0
REGS1_k127_8700293_0 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003471 266.0
REGS1_k127_8700293_1 SMART RNA-binding S4 domain protein K04762 - - 0.00000000000000000000000000000000000000001324 156.0
REGS1_k127_8700293_10 - - - - 0.0002151 48.0
REGS1_k127_8700293_3 Large exoproteins involved in heme utilization or adhesion K15125 - - 0.00000000000000000001664 107.0
REGS1_k127_8700293_4 Type VI secretion system effector, Hcp - - - 0.00000000000000005504 82.0
REGS1_k127_8700293_5 intein-mediated protein splicing K00525,K14415 - 1.17.4.1,6.5.1.3 0.00000000000000005737 96.0
REGS1_k127_8700293_6 - - - - 0.000000000001931 72.0
REGS1_k127_8700293_7 - - - - 0.00000000001761 68.0
REGS1_k127_8700293_8 COG3209 Rhs family protein - - - 0.000000002785 61.0
REGS1_k127_8700293_9 - - - - 0.0000139 52.0
REGS1_k127_8735607_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 5.387e-293 909.0
REGS1_k127_8735607_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 437.0
REGS1_k127_8735607_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 382.0
REGS1_k127_8735607_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006964 279.0
REGS1_k127_8829765_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1094.0
REGS1_k127_8829765_1 MgsA AAA+ ATPase C terminal K07478 - - 9.871e-243 754.0
REGS1_k127_8829765_10 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 287.0
REGS1_k127_8829765_11 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002823 278.0
REGS1_k127_8829765_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000962 258.0
REGS1_k127_8829765_13 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000007451 242.0
REGS1_k127_8829765_14 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000006472 221.0
REGS1_k127_8829765_15 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000006416 204.0
REGS1_k127_8829765_16 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000004676 199.0
REGS1_k127_8829765_17 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000001283 179.0
REGS1_k127_8829765_18 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000006258 167.0
REGS1_k127_8829765_19 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000007399 132.0
REGS1_k127_8829765_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.012e-225 706.0
REGS1_k127_8829765_3 PFAM ATP-binding region ATPase domain protein - - - 1.608e-197 632.0
REGS1_k127_8829765_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 598.0
REGS1_k127_8829765_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 552.0
REGS1_k127_8829765_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 577.0
REGS1_k127_8829765_7 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 469.0
REGS1_k127_8829765_8 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 467.0
REGS1_k127_8829765_9 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 308.0
REGS1_k127_883138_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1037.0
REGS1_k127_883138_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.372e-248 772.0
REGS1_k127_883138_10 - - - - 0.0000000000000000000000000000000000000000000004266 171.0
REGS1_k127_883138_11 Roadblock/LC7 domain K07131 - - 0.00000000000000000000000000116 116.0
REGS1_k127_883138_12 - - - - 0.00000000001849 72.0
REGS1_k127_883138_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 5.672e-197 620.0
REGS1_k127_883138_3 PFAM Dual specificity protein phosphatase K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 336.0
REGS1_k127_883138_4 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000008327 251.0
REGS1_k127_883138_5 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005027 258.0
REGS1_k127_883138_6 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000000000000007759 207.0
REGS1_k127_883138_7 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000000000002565 196.0
REGS1_k127_883138_8 GTP-binding domain protein K06945 - - 0.00000000000000000000000000000000000000000000000004452 186.0
REGS1_k127_883138_9 NADP transhydrogenase K00322,K00324 - 1.6.1.1,1.6.1.2 0.00000000000000000000000000000000000000000000008315 169.0
REGS1_k127_8833784_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1537.0
REGS1_k127_8833784_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1303.0
REGS1_k127_8833784_10 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 6.219e-198 621.0
REGS1_k127_8833784_11 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 582.0
REGS1_k127_8833784_12 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 572.0
REGS1_k127_8833784_13 PFAM type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 514.0
REGS1_k127_8833784_14 SMART adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 519.0
REGS1_k127_8833784_15 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 441.0
REGS1_k127_8833784_16 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 406.0
REGS1_k127_8833784_17 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 414.0
REGS1_k127_8833784_18 S4 RNA-binding domain K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 395.0
REGS1_k127_8833784_19 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 357.0
REGS1_k127_8833784_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 2.585e-299 926.0
REGS1_k127_8833784_20 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 360.0
REGS1_k127_8833784_21 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 316.0
REGS1_k127_8833784_22 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 290.0
REGS1_k127_8833784_23 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 290.0
REGS1_k127_8833784_24 Protein of unknown function (DUF560) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008395 255.0
REGS1_k127_8833784_25 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000003865 160.0
REGS1_k127_8833784_26 PFAM FecR protein K03832 - - 0.000000000000000000000000000000002341 139.0
REGS1_k127_8833784_27 - - - - 0.0000000000000000000001116 102.0
REGS1_k127_8833784_28 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000002014 98.0
REGS1_k127_8833784_29 Domain of unknown function (DUF4124) - - - 0.00000000000000000004248 98.0
REGS1_k127_8833784_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.018e-268 837.0
REGS1_k127_8833784_30 TIGRFAM PAS sensor protein - - - 0.000000000000000106 94.0
REGS1_k127_8833784_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.828e-257 797.0
REGS1_k127_8833784_5 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 6.075e-227 706.0
REGS1_k127_8833784_6 TIGRFAM fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 7.059e-223 692.0
REGS1_k127_8833784_7 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 2.377e-216 679.0
REGS1_k127_8833784_8 NeuB family K03856 - 2.5.1.54 3.859e-204 637.0
REGS1_k127_8833784_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 5.755e-198 619.0
REGS1_k127_8891429_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1379.0
REGS1_k127_8891429_1 histidine kinase HAMP region domain protein - - - 1.482e-274 861.0
REGS1_k127_8891429_10 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 290.0
REGS1_k127_8891429_11 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001489 276.0
REGS1_k127_8891429_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
REGS1_k127_8891429_13 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005469 214.0
REGS1_k127_8891429_14 Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000000000000000000000000000000000000000000004345 211.0
REGS1_k127_8891429_15 COG2346, Truncated hemoglobins K03406,K06886 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 - 0.000000000000000000000000000000000000000000000000000000000004466 210.0
REGS1_k127_8891429_16 Protein of unknown function (DUF494) K03747 - - 0.000000000000000000000000000000000000000000000000000000000007131 211.0
REGS1_k127_8891429_17 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000001556 191.0
REGS1_k127_8891429_18 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000000000002365 192.0
REGS1_k127_8891429_19 TIGRFAM transcriptional regulator, Rrf2 family K13771 - - 0.00000000000000000000000000000000000000000000009327 172.0
REGS1_k127_8891429_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 579.0
REGS1_k127_8891429_20 PFAM ABC-2 type transporter K09694 - - 0.000000000000002337 76.0
REGS1_k127_8891429_3 PFAM ABC transporter related K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 484.0
REGS1_k127_8891429_4 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 473.0
REGS1_k127_8891429_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 417.0
REGS1_k127_8891429_6 Oxidoreductase FAD-binding domain K14581 - 1.18.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 412.0
REGS1_k127_8891429_7 VanZ like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 381.0
REGS1_k127_8891429_8 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 376.0
REGS1_k127_8891429_9 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 376.0
REGS1_k127_8919246_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1482.0
REGS1_k127_8919246_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 3.396e-258 807.0
REGS1_k127_8919246_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 563.0
REGS1_k127_8919246_11 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 550.0
REGS1_k127_8919246_12 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 546.0
REGS1_k127_8919246_13 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 544.0
REGS1_k127_8919246_14 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 505.0
REGS1_k127_8919246_15 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 502.0
REGS1_k127_8919246_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 478.0
REGS1_k127_8919246_17 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 463.0
REGS1_k127_8919246_18 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 465.0
REGS1_k127_8919246_19 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 461.0
REGS1_k127_8919246_2 Mur ligase family, catalytic domain K01924 - 6.3.2.8 1.723e-248 774.0
REGS1_k127_8919246_20 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 416.0
REGS1_k127_8919246_21 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 309.0
REGS1_k127_8919246_22 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001703 275.0
REGS1_k127_8919246_23 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
REGS1_k127_8919246_24 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008198 240.0
REGS1_k127_8919246_25 Protein of unknown function (DUF2569) - - - 0.00000000000000000000000000000000000000000000000000000001266 201.0
REGS1_k127_8919246_26 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000002737 175.0
REGS1_k127_8919246_27 POTRA domain, FtsQ-type - - - 0.0000000000000000000000000000000000000000002852 166.0
REGS1_k127_8919246_28 Bacterial regulatory protein, Fis family K03557 - - 0.0000000000000000000000000000000001234 134.0
REGS1_k127_8919246_29 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000000000356 113.0
REGS1_k127_8919246_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.918e-226 706.0
REGS1_k127_8919246_31 Protein of unknown function (DUF721) - - - 0.00000000000000007296 86.0
REGS1_k127_8919246_33 - - - - 0.00000000346 61.0
REGS1_k127_8919246_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 1.436e-209 657.0
REGS1_k127_8919246_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 4.732e-209 660.0
REGS1_k127_8919246_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 9.464e-200 626.0
REGS1_k127_8919246_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 608.0
REGS1_k127_8919246_8 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 589.0
REGS1_k127_8919246_9 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 562.0
REGS1_k127_8933049_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1230.0
REGS1_k127_8933049_1 Participates in both transcription termination and antitermination K02600 - - 8.253e-266 826.0
REGS1_k127_8933049_2 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 564.0
REGS1_k127_8933049_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 403.0
REGS1_k127_8933049_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000101 221.0
REGS1_k127_8933049_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000361 178.0
REGS1_k127_8973715_0 Amino acid permease - - - 5.636e-214 677.0
REGS1_k127_8973715_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 410.0
REGS1_k127_8973715_2 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000002206 235.0
REGS1_k127_908036_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1360.0
REGS1_k127_908036_1 Peptidase dimerisation domain K01270 - - 5.791e-239 747.0
REGS1_k127_908036_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000004236 172.0
REGS1_k127_908036_11 OmpA family K02557 - - 0.0000000000000000000000000000000000000000006404 166.0
REGS1_k127_908036_12 - - - - 0.0000000000000000000000000000003059 127.0
REGS1_k127_908036_13 anaerobic respiration K02568 GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114 - 0.0000000000000000000000006967 117.0
REGS1_k127_908036_14 - - - - 0.00002168 56.0
REGS1_k127_908036_2 Domain of unknown function (DUF3520) K07114 - - 2.562e-203 649.0
REGS1_k127_908036_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 507.0
REGS1_k127_908036_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 443.0
REGS1_k127_908036_5 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 418.0
REGS1_k127_908036_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 325.0
REGS1_k127_908036_7 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 316.0
REGS1_k127_908036_8 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 320.0
REGS1_k127_908036_9 Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000008061 182.0
REGS1_k127_9089456_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 4.368e-238 744.0
REGS1_k127_9089456_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 505.0
REGS1_k127_9089456_2 PFAM permease YjgP YjgQ family protein K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 485.0
REGS1_k127_9096434_0 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 414.0
REGS1_k127_9096434_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000001036 236.0
REGS1_k127_9096434_2 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000005894 194.0
REGS1_k127_9096434_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000002017 191.0
REGS1_k127_9108333_0 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006395 273.0
REGS1_k127_9108333_1 SlyX K03745 - - 0.00000000000000000000007326 100.0
REGS1_k127_9108333_2 - - - - 0.000000000000000000004513 104.0
REGS1_k127_9119122_0 Domain of unknown function (DUF1926) K22451 - 2.4.1.25 4.204e-276 863.0
REGS1_k127_9119122_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 474.0
REGS1_k127_9119122_2 PFAM ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 331.0
REGS1_k127_9119122_3 Transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000001602 61.0
REGS1_k127_9119122_4 - - - - 0.00000002821 61.0
REGS1_k127_912320_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.0 1034.0
REGS1_k127_912320_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.099e-249 775.0
REGS1_k127_912320_10 Carbohydrate-selective porin, OprB family - - - 0.00002545 50.0
REGS1_k127_912320_2 Multi-copper - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 469.0
REGS1_k127_912320_3 Copper binding proteins, plastocyanin/azurin family K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 373.0
REGS1_k127_912320_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 328.0
REGS1_k127_912320_5 cytochrome C, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002603 256.0
REGS1_k127_912320_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000337 253.0
REGS1_k127_912320_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000003067 202.0
REGS1_k127_912320_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000001602 148.0
REGS1_k127_912320_9 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000002215 142.0
REGS1_k127_9168890_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1629.0
REGS1_k127_9168890_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1229.0
REGS1_k127_9168890_10 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005241 268.0
REGS1_k127_9168890_11 Peptidoglycan-synthase activator LpoB K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001444 258.0
REGS1_k127_9168890_12 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000001383 238.0
REGS1_k127_9168890_13 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001994 233.0
REGS1_k127_9168890_14 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000311 215.0
REGS1_k127_9168890_15 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000001528 187.0
REGS1_k127_9168890_16 LPP20 lipoprotein - - - 0.000000000000000000000000000000000000000000001139 178.0
REGS1_k127_9168890_17 monooxygenase activity - - - 0.0000000000000000000000000000000000000000001986 164.0
REGS1_k127_9168890_18 LPP20 lipoprotein - - - 0.00000000000000000000000000000000009111 143.0
REGS1_k127_9168890_19 - - - - 0.000000000000000000000000000001188 126.0
REGS1_k127_9168890_2 type ii restriction enzyme K01155 - 3.1.21.4 1.096e-200 632.0
REGS1_k127_9168890_20 Protein of unknown function (DUF2933) - - - 0.000000000000000000000000000006516 120.0
REGS1_k127_9168890_22 - - - - 0.00000000005491 68.0
REGS1_k127_9168890_23 transposase activity K07483,K07497 - - 0.0000000001409 72.0
REGS1_k127_9168890_24 - - - - 0.0000002489 58.0
REGS1_k127_9168890_3 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 612.0
REGS1_k127_9168890_4 TIGRFAM efflux transporter, RND family, MFP subunit K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 563.0
REGS1_k127_9168890_5 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 554.0
REGS1_k127_9168890_6 Sigma-70 factor, region 1.2 K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 416.0
REGS1_k127_9168890_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 358.0
REGS1_k127_9168890_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 343.0
REGS1_k127_9168890_9 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 319.0
REGS1_k127_9181776_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 551.0
REGS1_k127_9181776_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 482.0
REGS1_k127_9181776_2 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 340.0
REGS1_k127_9181776_3 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 342.0
REGS1_k127_9181776_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000442 119.0
REGS1_k127_9181776_5 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 0.00000013 53.0
REGS1_k127_987141_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.2e-287 893.0
REGS1_k127_987141_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.259e-272 843.0
REGS1_k127_987141_10 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 353.0
REGS1_k127_987141_11 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 338.0
REGS1_k127_987141_12 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 290.0
REGS1_k127_987141_13 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 291.0
REGS1_k127_987141_14 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 264.0
REGS1_k127_987141_15 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006958 253.0
REGS1_k127_987141_16 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000001045 209.0
REGS1_k127_987141_17 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000000992 186.0
REGS1_k127_987141_18 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000000000000000000005558 189.0
REGS1_k127_987141_19 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000004667 161.0
REGS1_k127_987141_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 2.325e-224 704.0
REGS1_k127_987141_20 VTC domain - - - 0.000000000001284 71.0
REGS1_k127_987141_21 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00004065 56.0
REGS1_k127_987141_22 Helix-turn-helix domain - - - 0.0002844 47.0
REGS1_k127_987141_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 479.0
REGS1_k127_987141_4 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 478.0
REGS1_k127_987141_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 445.0
REGS1_k127_987141_6 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 428.0
REGS1_k127_987141_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 430.0
REGS1_k127_987141_8 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 411.0
REGS1_k127_987141_9 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 402.0