Overview

ID MAG03335
Name REGS2_bin.24
Sample SMP0080
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Coriobacteriia
Order Anaerosomatales
Family PALSA-660
Genus JANYAK01
Species
Assembly information
Completeness (%) 90.52
Contamination (%) 2.27
GC content (%) 69.0
N50 (bp) 20,329
Genome size (bp) 1,703,790

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1562

Gene name Description KEGG GOs EC E-value Score Sequence
REGS2_k127_1058823_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1140.0
REGS2_k127_1058823_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 600.0
REGS2_k127_1058823_10 Transporter associated domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000002267 207.0
REGS2_k127_1058823_11 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000002228 198.0
REGS2_k127_1058823_12 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.000000000000000000000000000000000000000000000000004922 191.0
REGS2_k127_1058823_13 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000001795 181.0
REGS2_k127_1058823_14 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000009012 155.0
REGS2_k127_1058823_15 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000009808 150.0
REGS2_k127_1058823_16 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000001213 128.0
REGS2_k127_1058823_17 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000002529 128.0
REGS2_k127_1058823_18 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000006746 124.0
REGS2_k127_1058823_19 PFAM SpoVT AbrB K07172 - - 0.000000000000000000000003706 105.0
REGS2_k127_1058823_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 490.0
REGS2_k127_1058823_20 Antitoxin Phd_YefM, type II toxin-antitoxin system K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.000000001656 63.0
REGS2_k127_1058823_21 Transcriptional regulator - - - 0.000000003924 65.0
REGS2_k127_1058823_22 Domain of unknown function (DUF4339) - - - 0.0000006078 62.0
REGS2_k127_1058823_23 PFAM SpoVT AbrB - - - 0.000004244 53.0
REGS2_k127_1058823_24 PIN domain - - - 0.00001217 53.0
REGS2_k127_1058823_3 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 413.0
REGS2_k127_1058823_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 356.0
REGS2_k127_1058823_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 352.0
REGS2_k127_1058823_6 RNA modification enzyme, MiaB family K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 309.0
REGS2_k127_1058823_7 SMART Metal-dependent phosphohydrolase, HD region K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001511 265.0
REGS2_k127_1058823_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004511 252.0
REGS2_k127_1058823_9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000001676 236.0
REGS2_k127_1081694_0 Required for chromosome condensation and partitioning K03529 - - 6.095e-284 913.0
REGS2_k127_1081694_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 516.0
REGS2_k127_1081694_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 324.0
REGS2_k127_1081694_11 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 308.0
REGS2_k127_1081694_12 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003654 280.0
REGS2_k127_1081694_13 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003035 277.0
REGS2_k127_1081694_14 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008675 271.0
REGS2_k127_1081694_15 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006002 274.0
REGS2_k127_1081694_16 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000006944 252.0
REGS2_k127_1081694_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000002377 230.0
REGS2_k127_1081694_18 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000003368 231.0
REGS2_k127_1081694_19 RIP metalloprotease RseP K11749 - - 0.000000000000000000000000000000000000000000000000000000000001098 226.0
REGS2_k127_1081694_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 515.0
REGS2_k127_1081694_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000003528 184.0
REGS2_k127_1081694_21 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000002819 181.0
REGS2_k127_1081694_22 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000003883 184.0
REGS2_k127_1081694_23 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000009521 170.0
REGS2_k127_1081694_24 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000005537 162.0
REGS2_k127_1081694_25 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000003525 171.0
REGS2_k127_1081694_26 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000005582 127.0
REGS2_k127_1081694_27 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000002353 109.0
REGS2_k127_1081694_28 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000002611 110.0
REGS2_k127_1081694_29 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000511 100.0
REGS2_k127_1081694_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 472.0
REGS2_k127_1081694_30 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000001188 100.0
REGS2_k127_1081694_31 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000008021 98.0
REGS2_k127_1081694_32 Belongs to the UPF0109 family K06960 - - 0.0000000000000004418 81.0
REGS2_k127_1081694_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 435.0
REGS2_k127_1081694_5 Mg chelatase-like protein K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 411.0
REGS2_k127_1081694_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 384.0
REGS2_k127_1081694_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 357.0
REGS2_k127_1081694_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 363.0
REGS2_k127_1081694_9 PFAM 2-nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 350.0
REGS2_k127_122691_0 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 9.427e-222 718.0
REGS2_k127_122691_1 PFAM sigma-54 factor interaction domain-containing protein K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 442.0
REGS2_k127_122691_10 Stage II sporulation - - - 0.0000000000000000000000000000000000000000000002398 193.0
REGS2_k127_122691_11 cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000008034 173.0
REGS2_k127_122691_12 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000002759 167.0
REGS2_k127_122691_13 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000003041 172.0
REGS2_k127_122691_14 Thioredoxin K03671 - - 0.000000000000000000000000000001375 123.0
REGS2_k127_122691_15 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000159 117.0
REGS2_k127_122691_16 Nitroreductase family - - - 0.00000000000000000000004419 106.0
REGS2_k127_122691_17 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000004978 102.0
REGS2_k127_122691_18 Domain of unknown function DUF302 - - - 0.0000000000000007998 85.0
REGS2_k127_122691_19 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.000000000000234 83.0
REGS2_k127_122691_2 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 424.0
REGS2_k127_122691_20 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.000000000001664 72.0
REGS2_k127_122691_21 Heavy-metal-associated domain - - - 0.000000001858 61.0
REGS2_k127_122691_22 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000001616 62.0
REGS2_k127_122691_23 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00003312 56.0
REGS2_k127_122691_24 4Fe-4S single cluster domain - - - 0.00006954 55.0
REGS2_k127_122691_3 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 293.0
REGS2_k127_122691_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 302.0
REGS2_k127_122691_5 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006729 295.0
REGS2_k127_122691_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001423 276.0
REGS2_k127_122691_7 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000001987 208.0
REGS2_k127_122691_8 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000001896 184.0
REGS2_k127_122691_9 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000327 182.0
REGS2_k127_1246596_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1116.0
REGS2_k127_1246596_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 497.0
REGS2_k127_1246596_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000001557 198.0
REGS2_k127_1246596_11 YacP-like NYN domain K06962 - - 0.0000000000000000000001012 104.0
REGS2_k127_1246596_12 NACHT domain - - - 0.0000000000003239 78.0
REGS2_k127_1246596_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 424.0
REGS2_k127_1246596_3 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 335.0
REGS2_k127_1246596_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 308.0
REGS2_k127_1246596_5 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000861 266.0
REGS2_k127_1246596_6 Integral membrane protein (Pin domain superfamily) - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001381 264.0
REGS2_k127_1246596_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
REGS2_k127_1246596_8 PFAM sigma-70 region 2 domain protein K03091 - - 0.000000000000000000000000000000000000000000000000000000000000002381 225.0
REGS2_k127_1246596_9 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000001347 213.0
REGS2_k127_1351705_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 572.0
REGS2_k127_1351705_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 566.0
REGS2_k127_1351705_10 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000005568 158.0
REGS2_k127_1351705_11 ACT domain protein - - - 0.000000000000000000000000000000001997 145.0
REGS2_k127_1351705_12 (FHA) domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.0000000000000000000000000000007146 127.0
REGS2_k127_1351705_13 - - - - 0.0000000000001107 79.0
REGS2_k127_1351705_14 Diguanylate cyclase, GGDEF domain - - - 0.000003392 58.0
REGS2_k127_1351705_15 Prokaryotic N-terminal methylation motif - - - 0.0007364 48.0
REGS2_k127_1351705_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 429.0
REGS2_k127_1351705_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 306.0
REGS2_k127_1351705_4 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000001744 245.0
REGS2_k127_1351705_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000002127 252.0
REGS2_k127_1351705_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000001788 184.0
REGS2_k127_1351705_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000829 177.0
REGS2_k127_1351705_8 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000007788 162.0
REGS2_k127_1351705_9 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.0000000000000000000000000000000000000127 150.0
REGS2_k127_1455695_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 479.0
REGS2_k127_1455695_1 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 390.0
REGS2_k127_1455695_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 360.0
REGS2_k127_1455695_3 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 325.0
REGS2_k127_1455695_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000008609 220.0
REGS2_k127_1455695_5 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000002854 205.0
REGS2_k127_1455695_6 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000003914 184.0
REGS2_k127_1455695_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000001681 177.0
REGS2_k127_1455695_8 - - - - 0.000000001037 72.0
REGS2_k127_1531905_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.477e-221 706.0
REGS2_k127_1531905_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 577.0
REGS2_k127_1531905_10 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 318.0
REGS2_k127_1531905_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005257 277.0
REGS2_k127_1531905_12 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007006 250.0
REGS2_k127_1531905_13 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000002357 252.0
REGS2_k127_1531905_14 PFAM Membrane protein of K08972 - - 0.0000000000001015 76.0
REGS2_k127_1531905_15 Preprotein translocase SecG subunit K03075 - - 0.0000000000009499 70.0
REGS2_k127_1531905_16 Psort location Extracellular, score 9.55 - - - 0.000000000003688 78.0
REGS2_k127_1531905_17 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000006045 80.0
REGS2_k127_1531905_2 ABC transporter, ATP-binding protein K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 499.0
REGS2_k127_1531905_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 488.0
REGS2_k127_1531905_4 pathway, signal sequence K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 492.0
REGS2_k127_1531905_5 ABC transporter, ATP-binding protein K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 474.0
REGS2_k127_1531905_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 478.0
REGS2_k127_1531905_7 May be required for sporulation K09762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 376.0
REGS2_k127_1531905_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 344.0
REGS2_k127_1531905_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 315.0
REGS2_k127_1774685_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 8.788e-204 648.0
REGS2_k127_1774685_1 FtsK SpoIIIE family K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 622.0
REGS2_k127_1774685_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000009335 94.0
REGS2_k127_1774685_11 Helix-turn-helix domain - - - 0.0000000000000006645 88.0
REGS2_k127_1774685_12 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000003161 77.0
REGS2_k127_1774685_13 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000002271 69.0
REGS2_k127_1774685_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 548.0
REGS2_k127_1774685_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 509.0
REGS2_k127_1774685_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 374.0
REGS2_k127_1774685_5 competence damage-inducible protein CinA K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000001183 256.0
REGS2_k127_1774685_6 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000008244 216.0
REGS2_k127_1774685_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000202 188.0
REGS2_k127_1774685_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000002238 171.0
REGS2_k127_1774685_9 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000008178 131.0
REGS2_k127_1849630_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 3.133e-230 739.0
REGS2_k127_1849630_1 G5 - - - 0.000000000000000000000000000000000000000000000000000000000002345 233.0
REGS2_k127_1849630_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000009369 207.0
REGS2_k127_1849630_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000008333 146.0
REGS2_k127_1849630_4 Belongs to the UPF0337 (CsbD) family - - - 0.0000000001237 68.0
REGS2_k127_2043212_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 9.017e-260 824.0
REGS2_k127_2043212_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 531.0
REGS2_k127_2043212_10 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000008903 222.0
REGS2_k127_2043212_11 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000003258 205.0
REGS2_k127_2043212_12 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000009163 196.0
REGS2_k127_2043212_13 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000001443 168.0
REGS2_k127_2043212_14 PFAM Stage V sporulation protein S K06416 - - 0.0000000000000000000000000000000000002065 143.0
REGS2_k127_2043212_15 NUDIX domain - - - 0.00000000000002935 81.0
REGS2_k127_2043212_16 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000009512 55.0
REGS2_k127_2043212_17 lytic transglycosylase K08307 - - 0.0005322 49.0
REGS2_k127_2043212_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 479.0
REGS2_k127_2043212_3 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 457.0
REGS2_k127_2043212_4 pfam ammecr1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 383.0
REGS2_k127_2043212_5 histidine kinase DNA gyrase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 361.0
REGS2_k127_2043212_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 317.0
REGS2_k127_2043212_7 permease K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 318.0
REGS2_k127_2043212_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002078 274.0
REGS2_k127_2043212_9 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000006291 257.0
REGS2_k127_2111925_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 527.0
REGS2_k127_2111925_1 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 511.0
REGS2_k127_2111925_10 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000005153 199.0
REGS2_k127_2111925_11 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000002475 173.0
REGS2_k127_2111925_12 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000005704 153.0
REGS2_k127_2111925_13 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000001161 149.0
REGS2_k127_2111925_14 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000002029 143.0
REGS2_k127_2111925_15 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.00000000000000000000000000000002325 140.0
REGS2_k127_2111925_16 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000117 123.0
REGS2_k127_2111925_17 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000161 117.0
REGS2_k127_2111925_18 peptidase S1 and S6, chymotrypsin Hap K01337 - 3.4.21.50 0.000000000000000000000002789 119.0
REGS2_k127_2111925_19 membrane K09790 - - 0.00000000000000000000006937 102.0
REGS2_k127_2111925_2 PFAM Alcohol dehydrogenase GroES-like K00004,K00008,K00060 - 1.1.1.103,1.1.1.14,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 502.0
REGS2_k127_2111925_20 intracellular protein transport K05989 - 3.2.1.40 0.00000000000000000009271 104.0
REGS2_k127_2111925_21 phosphorelay signal transduction system - - - 0.000000000000000003376 92.0
REGS2_k127_2111925_22 - - - - 0.000000000000001899 88.0
REGS2_k127_2111925_23 Histidine kinase K07675 - 2.7.13.3 0.000000005142 67.0
REGS2_k127_2111925_24 Nucleotidyltransferase - - - 0.0000002353 59.0
REGS2_k127_2111925_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 433.0
REGS2_k127_2111925_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 412.0
REGS2_k127_2111925_5 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 299.0
REGS2_k127_2111925_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 286.0
REGS2_k127_2111925_7 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002742 267.0
REGS2_k127_2111925_8 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000003122 249.0
REGS2_k127_2111925_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
REGS2_k127_2256571_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 1.536e-268 839.0
REGS2_k127_2256571_1 TIGRFAM DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 5.163e-225 737.0
REGS2_k127_2256571_10 fructose-1,6-bisphosphatase K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 371.0
REGS2_k127_2256571_11 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 370.0
REGS2_k127_2256571_12 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 298.0
REGS2_k127_2256571_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007361 282.0
REGS2_k127_2256571_14 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 265.0
REGS2_k127_2256571_15 TIGRFAM histidinol phosphate phosphatase HisJ K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000008433 262.0
REGS2_k127_2256571_16 DNA polymerase III, epsilon subunit K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000004863 266.0
REGS2_k127_2256571_17 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000001035 250.0
REGS2_k127_2256571_18 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000002066 232.0
REGS2_k127_2256571_19 DAK2 domain fusion protein YloV K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000002457 232.0
REGS2_k127_2256571_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 1.266e-211 704.0
REGS2_k127_2256571_20 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000001462 228.0
REGS2_k127_2256571_21 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000006828 215.0
REGS2_k127_2256571_22 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000001136 209.0
REGS2_k127_2256571_23 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000007441 202.0
REGS2_k127_2256571_24 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000008446 191.0
REGS2_k127_2256571_25 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000005363 202.0
REGS2_k127_2256571_26 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000007729 190.0
REGS2_k127_2256571_27 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000004192 177.0
REGS2_k127_2256571_28 COG1321 Mn-dependent transcriptional regulator K03709 - - 0.000000000000000000000000000000000000003603 154.0
REGS2_k127_2256571_29 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000000000000000000008556 146.0
REGS2_k127_2256571_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 596.0
REGS2_k127_2256571_30 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000001504 138.0
REGS2_k127_2256571_31 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000229 143.0
REGS2_k127_2256571_32 thiamine transport K16789 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000008785 139.0
REGS2_k127_2256571_33 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000002148 134.0
REGS2_k127_2256571_34 heme binding K21471,K21472 - - 0.0000000000000000000000000000002228 139.0
REGS2_k127_2256571_35 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000001552 135.0
REGS2_k127_2256571_36 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000007538 124.0
REGS2_k127_2256571_37 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000008866 103.0
REGS2_k127_2256571_38 zinc ribbon domain K07164 - - 0.0000000000000000002362 96.0
REGS2_k127_2256571_39 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.0000000000000000312 95.0
REGS2_k127_2256571_4 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 577.0
REGS2_k127_2256571_40 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000001516 83.0
REGS2_k127_2256571_41 Regulatory protein, FmdB family - - - 0.000000000008516 78.0
REGS2_k127_2256571_42 - - - - 0.000000002064 63.0
REGS2_k127_2256571_43 - - - - 0.00000007626 59.0
REGS2_k127_2256571_44 type 3a cellulose-binding domain protein K01179,K05988 - 3.2.1.11,3.2.1.4 0.00000236 59.0
REGS2_k127_2256571_45 Domain of unknown function (DUF1858) - - - 0.000003359 57.0
REGS2_k127_2256571_46 Phosphate-starvation-inducible E - - - 0.00002368 54.0
REGS2_k127_2256571_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 560.0
REGS2_k127_2256571_6 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 561.0
REGS2_k127_2256571_7 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 514.0
REGS2_k127_2256571_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 434.0
REGS2_k127_2256571_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 388.0
REGS2_k127_2392567_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 610.0
REGS2_k127_2392567_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 551.0
REGS2_k127_2392567_10 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000009071 144.0
REGS2_k127_2392567_11 NIL domain - - - 0.0000000000000000000000000000002033 127.0
REGS2_k127_2392567_12 Virulence activator alpha C-term - - - 0.00000000000000000000000000000666 125.0
REGS2_k127_2392567_13 PFAM ThiamineS - - - 0.0000000003963 63.0
REGS2_k127_2392567_2 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 498.0
REGS2_k127_2392567_3 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 504.0
REGS2_k127_2392567_4 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000003836 260.0
REGS2_k127_2392567_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000002462 218.0
REGS2_k127_2392567_6 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000005049 183.0
REGS2_k127_2392567_7 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 0.000000000000000000000000000000000000000000004127 174.0
REGS2_k127_2392567_8 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000007671 168.0
REGS2_k127_2392567_9 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000002436 162.0
REGS2_k127_2460090_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.454e-247 771.0
REGS2_k127_2460090_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.664e-225 704.0
REGS2_k127_2460090_10 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 332.0
REGS2_k127_2460090_11 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 324.0
REGS2_k127_2460090_12 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 309.0
REGS2_k127_2460090_13 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000064 298.0
REGS2_k127_2460090_14 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001487 256.0
REGS2_k127_2460090_15 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001208 278.0
REGS2_k127_2460090_16 Bacterial transferase hexapeptide K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000597 260.0
REGS2_k127_2460090_17 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000002028 256.0
REGS2_k127_2460090_18 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
REGS2_k127_2460090_19 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000463 186.0
REGS2_k127_2460090_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 617.0
REGS2_k127_2460090_20 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000006395 177.0
REGS2_k127_2460090_21 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000001325 183.0
REGS2_k127_2460090_22 isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000009672 174.0
REGS2_k127_2460090_23 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000004011 151.0
REGS2_k127_2460090_24 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000001796 139.0
REGS2_k127_2460090_25 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000006606 107.0
REGS2_k127_2460090_26 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000009746 104.0
REGS2_k127_2460090_27 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000005309 83.0
REGS2_k127_2460090_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 582.0
REGS2_k127_2460090_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 507.0
REGS2_k127_2460090_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0008150,GO:0040007 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 490.0
REGS2_k127_2460090_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 465.0
REGS2_k127_2460090_7 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 408.0
REGS2_k127_2460090_8 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 386.0
REGS2_k127_2460090_9 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 346.0
REGS2_k127_2715638_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 556.0
REGS2_k127_2715638_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 459.0
REGS2_k127_2715638_10 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000268 159.0
REGS2_k127_2715638_11 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000004578 167.0
REGS2_k127_2715638_12 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000002445 146.0
REGS2_k127_2715638_13 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000001703 136.0
REGS2_k127_2715638_14 Could be involved in septation K06412 - - 0.0000000000000000000001036 101.0
REGS2_k127_2715638_15 Domain of unknown function (DUF4870) - - - 0.000001099 55.0
REGS2_k127_2715638_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 364.0
REGS2_k127_2715638_3 domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 293.0
REGS2_k127_2715638_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000003421 274.0
REGS2_k127_2715638_5 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000002366 223.0
REGS2_k127_2715638_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000008031 202.0
REGS2_k127_2715638_7 PFAM Peptidase M23 K21471 - - 0.0000000000000000000000000000000000000000000000000002428 201.0
REGS2_k127_2715638_8 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000000000006695 173.0
REGS2_k127_2715638_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000009847 164.0
REGS2_k127_2761972_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 590.0
REGS2_k127_2761972_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 522.0
REGS2_k127_2761972_10 L,D-transpeptidase catalytic domain - - - 0.0000000004067 69.0
REGS2_k127_2761972_11 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 - 4.1.3.38 0.0000006475 62.0
REGS2_k127_2761972_12 - - - - 0.0001548 46.0
REGS2_k127_2761972_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 451.0
REGS2_k127_2761972_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 309.0
REGS2_k127_2761972_4 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 306.0
REGS2_k127_2761972_5 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000003691 240.0
REGS2_k127_2761972_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000001197 217.0
REGS2_k127_2761972_7 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000000000000000009814 199.0
REGS2_k127_2761972_8 PFAM plasmid stabilization system - - - 0.00000000000000000000009695 100.0
REGS2_k127_2761972_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000009981 78.0
REGS2_k127_2767080_0 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571 - 4.1.1.3 1.369e-266 836.0
REGS2_k127_2767080_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.365e-248 777.0
REGS2_k127_2767080_10 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000172 292.0
REGS2_k127_2767080_11 Protein of unknown function (DUF3866) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005254 287.0
REGS2_k127_2767080_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002226 267.0
REGS2_k127_2767080_13 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002962 258.0
REGS2_k127_2767080_14 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000001618 254.0
REGS2_k127_2767080_15 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001112 238.0
REGS2_k127_2767080_16 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000655 231.0
REGS2_k127_2767080_17 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000003386 217.0
REGS2_k127_2767080_18 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000001089 193.0
REGS2_k127_2767080_19 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000009783 177.0
REGS2_k127_2767080_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 7.65e-229 726.0
REGS2_k127_2767080_20 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000123 140.0
REGS2_k127_2767080_21 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.000000000000000000000000000000006092 140.0
REGS2_k127_2767080_22 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000718 125.0
REGS2_k127_2767080_23 Asp23 family, cell envelope-related function - - - 0.00000000000000000007956 93.0
REGS2_k127_2767080_24 carbon utilization K02664,K02665,K12280 - - 0.000000000002498 75.0
REGS2_k127_2767080_25 PFAM Fimbrial assembly family protein K02663 - - 0.0000000003192 69.0
REGS2_k127_2767080_26 Copper transport outer membrane protein, MctB - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0008150,GO:0009279,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0044425,GO:0044462,GO:0044464,GO:0046930,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098796 - 0.00000000799 68.0
REGS2_k127_2767080_27 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00002681 51.0
REGS2_k127_2767080_3 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 597.0
REGS2_k127_2767080_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 514.0
REGS2_k127_2767080_5 Thiamine pyrophosphokinase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 428.0
REGS2_k127_2767080_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 404.0
REGS2_k127_2767080_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 389.0
REGS2_k127_2767080_8 integral membrane protein MviN K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 345.0
REGS2_k127_2767080_9 Peptidase dimerisation domain K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 341.0
REGS2_k127_2813707_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 545.0
REGS2_k127_2813707_1 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 421.0
REGS2_k127_2813707_2 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 284.0
REGS2_k127_2813707_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000003388 261.0
REGS2_k127_2813707_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000007526 231.0
REGS2_k127_2813707_5 - - - - 0.00000000000005207 78.0
REGS2_k127_2856742_0 Chemotaxis protein CheA K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 478.0
REGS2_k127_2856742_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 454.0
REGS2_k127_2856742_10 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000004509 200.0
REGS2_k127_2856742_11 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000004162 205.0
REGS2_k127_2856742_12 Peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000904 201.0
REGS2_k127_2856742_13 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000001079 192.0
REGS2_k127_2856742_14 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000194 195.0
REGS2_k127_2856742_15 Belongs to the peptidase M50B family K06402 - - 0.00000000000000000000000000000000000000000000007304 185.0
REGS2_k127_2856742_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000002387 174.0
REGS2_k127_2856742_17 Chemotaxis protein CheC K03410 - - 0.00000000000000000000000000000000000000000001075 169.0
REGS2_k127_2856742_18 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000001679 163.0
REGS2_k127_2856742_19 PFAM NLP P60 protein K21471 - - 0.0000000000000000000000000000000000000004778 163.0
REGS2_k127_2856742_2 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 434.0
REGS2_k127_2856742_20 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000005067 154.0
REGS2_k127_2856742_21 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000006208 156.0
REGS2_k127_2856742_22 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000009558 133.0
REGS2_k127_2856742_23 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000002871 132.0
REGS2_k127_2856742_24 PFAM CheW domain protein K03408 - - 0.0000000000000000000000009291 112.0
REGS2_k127_2856742_25 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000001397 107.0
REGS2_k127_2856742_26 VanZ like family - - - 0.00000000000000005493 85.0
REGS2_k127_2856742_27 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000008929 88.0
REGS2_k127_2856742_28 EamA-like transporter family - - - 0.000002731 59.0
REGS2_k127_2856742_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 396.0
REGS2_k127_2856742_4 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 386.0
REGS2_k127_2856742_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 354.0
REGS2_k127_2856742_6 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 304.0
REGS2_k127_2856742_7 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003591 277.0
REGS2_k127_2856742_8 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000004501 231.0
REGS2_k127_2856742_9 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000001189 218.0
REGS2_k127_2858830_0 PFAM AMP-dependent synthetase and ligase K00666 - - 6.953e-299 923.0
REGS2_k127_2858830_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.411e-242 769.0
REGS2_k127_2858830_10 Cupin domain K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006763 258.0
REGS2_k127_2858830_11 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002191 259.0
REGS2_k127_2858830_12 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005705 258.0
REGS2_k127_2858830_13 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002195 264.0
REGS2_k127_2858830_14 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000001456 243.0
REGS2_k127_2858830_15 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001679 241.0
REGS2_k127_2858830_16 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000004556 242.0
REGS2_k127_2858830_17 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000314 238.0
REGS2_k127_2858830_18 ATPases associated with a variety of cellular activities K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000002061 222.0
REGS2_k127_2858830_19 PFAM Capsule synthesis protein, CapA K07282 - - 0.00000000000000000000000000000000000000000000000000000000000005137 229.0
REGS2_k127_2858830_2 PFAM CoA-binding domain protein - - - 5.412e-209 674.0
REGS2_k127_2858830_20 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000003086 221.0
REGS2_k127_2858830_21 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000002764 200.0
REGS2_k127_2858830_22 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000005856 167.0
REGS2_k127_2858830_23 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000005455 163.0
REGS2_k127_2858830_24 DUF218 domain - - - 0.0000000000000000000000000000000000000000009968 169.0
REGS2_k127_2858830_25 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000003801 155.0
REGS2_k127_2858830_26 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000000000104 148.0
REGS2_k127_2858830_27 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000006298 147.0
REGS2_k127_2858830_28 transmembrane transport K01992 - - 0.000000000000000000000000000000000001542 148.0
REGS2_k127_2858830_29 protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000007028 154.0
REGS2_k127_2858830_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 573.0
REGS2_k127_2858830_30 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000415 130.0
REGS2_k127_2858830_31 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000001296 141.0
REGS2_k127_2858830_32 - - - - 0.000000000000000000000000000003805 124.0
REGS2_k127_2858830_33 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000003061 116.0
REGS2_k127_2858830_34 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000003573 124.0
REGS2_k127_2858830_35 Sortase family K07284,K22278 - 3.4.22.70,3.5.1.104 0.000000000000000000000000191 115.0
REGS2_k127_2858830_36 PFAM regulatory protein, MerR - - - 0.00000000000000000009254 99.0
REGS2_k127_2858830_38 - - - - 0.0000000000000002947 85.0
REGS2_k127_2858830_39 Type IV pilus biogenesis stability protein PilW - - - 0.000000005617 64.0
REGS2_k127_2858830_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 481.0
REGS2_k127_2858830_40 Protein of unknown function (DUF2510) - - - 0.0000001733 59.0
REGS2_k127_2858830_41 - - - - 0.00005192 53.0
REGS2_k127_2858830_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 352.0
REGS2_k127_2858830_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006859 295.0
REGS2_k127_2858830_7 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002485 269.0
REGS2_k127_2858830_8 Tocopherol cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003705 282.0
REGS2_k127_2858830_9 transferase activity, transferring glycosyl groups K19002 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 0.000000000000000000000000000000000000000000000000000000000000000000000000000006799 289.0
REGS2_k127_2859590_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 568.0
REGS2_k127_2859590_1 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 428.0
REGS2_k127_2859590_10 Flavodoxin-like fold - - - 0.0000000000000000000000000000001524 131.0
REGS2_k127_2859590_11 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000005847 97.0
REGS2_k127_2859590_12 Regulators of stationary sporulation gene expression K06284 - - 0.000000000000000000003204 97.0
REGS2_k127_2859590_13 Zn peptidase - - - 0.0000001276 60.0
REGS2_k127_2859590_2 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001151 251.0
REGS2_k127_2859590_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
REGS2_k127_2859590_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000003128 222.0
REGS2_k127_2859590_5 pfam rok K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000003451 214.0
REGS2_k127_2859590_6 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000003297 214.0
REGS2_k127_2859590_7 histidine kinase HAMP region domain protein K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000001153 185.0
REGS2_k127_2859590_8 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000000000000000000000000866 146.0
REGS2_k127_2859590_9 G5 domain protein - - - 0.000000000000000000000000000000000006379 151.0
REGS2_k127_2938282_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.21e-258 830.0
REGS2_k127_2938282_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 9.551e-201 635.0
REGS2_k127_2938282_2 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000002674 204.0
REGS2_k127_2938282_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000004728 134.0
REGS2_k127_2938282_4 Response regulator receiver - - - 0.00000000000000000000001422 108.0
REGS2_k127_2938282_5 COG0500 SAM-dependent methyltransferases K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000003305 103.0
REGS2_k127_2938282_6 - - - - 0.000000004986 67.0
REGS2_k127_2938282_7 Protein of unknown function (DUF3616) - - - 0.000002183 59.0
REGS2_k127_2960367_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.807e-226 712.0
REGS2_k127_2960367_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 481.0
REGS2_k127_2960367_2 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002793 279.0
REGS2_k127_2960367_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000002017 174.0
REGS2_k127_2960367_4 - - - - 0.00000000000000000000001378 118.0
REGS2_k127_2960367_5 - - - - 0.00000006491 61.0
REGS2_k127_2960367_6 PFAM SpoVT AbrB - - - 0.00001094 48.0
REGS2_k127_2968566_0 elongation factor G K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 557.0
REGS2_k127_2968566_1 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 458.0
REGS2_k127_2968566_10 - - - - 0.000000000000000000000000000000000000000000000000889 193.0
REGS2_k127_2968566_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000001773 184.0
REGS2_k127_2968566_12 DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000006755 170.0
REGS2_k127_2968566_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000001316 148.0
REGS2_k127_2968566_14 PFAM OsmC-like protein K07397 - - 0.0000000000000000000000001133 111.0
REGS2_k127_2968566_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000009178 102.0
REGS2_k127_2968566_16 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000002774 79.0
REGS2_k127_2968566_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 349.0
REGS2_k127_2968566_3 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001696 291.0
REGS2_k127_2968566_4 elongation factor G K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002907 264.0
REGS2_k127_2968566_5 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005611 253.0
REGS2_k127_2968566_6 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000001657 217.0
REGS2_k127_2968566_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000003111 205.0
REGS2_k127_2968566_8 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000009321 214.0
REGS2_k127_2968566_9 lipid kinase, YegS Rv2252 BmrU family - - - 0.0000000000000000000000000000000000000000000000000000003144 206.0
REGS2_k127_3026863_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.53e-321 1006.0
REGS2_k127_3026863_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 5.431e-258 818.0
REGS2_k127_3026863_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 473.0
REGS2_k127_3026863_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 389.0
REGS2_k127_3026863_4 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 366.0
REGS2_k127_3026863_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 338.0
REGS2_k127_3026863_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 320.0
REGS2_k127_3026863_7 Belongs to the peptidase S26 family - - - 0.0002017 53.0
REGS2_k127_3026863_8 cell adhesion involved in biofilm formation - - - 0.0006045 51.0
REGS2_k127_3138938_0 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 619.0
REGS2_k127_3138938_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 572.0
REGS2_k127_3138938_10 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 346.0
REGS2_k127_3138938_11 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 342.0
REGS2_k127_3138938_12 FeS-containing Cyanobacterial-specific oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 334.0
REGS2_k127_3138938_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 333.0
REGS2_k127_3138938_14 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 342.0
REGS2_k127_3138938_15 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 311.0
REGS2_k127_3138938_16 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001411 299.0
REGS2_k127_3138938_17 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003573 291.0
REGS2_k127_3138938_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
REGS2_k127_3138938_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002907 264.0
REGS2_k127_3138938_2 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 500.0
REGS2_k127_3138938_20 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000005542 265.0
REGS2_k127_3138938_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000004535 238.0
REGS2_k127_3138938_22 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000002876 249.0
REGS2_k127_3138938_23 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000005576 207.0
REGS2_k127_3138938_24 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000003044 208.0
REGS2_k127_3138938_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001803 188.0
REGS2_k127_3138938_26 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000008729 177.0
REGS2_k127_3138938_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000001115 171.0
REGS2_k127_3138938_28 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000007812 149.0
REGS2_k127_3138938_29 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000003504 152.0
REGS2_k127_3138938_3 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 463.0
REGS2_k127_3138938_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000001518 123.0
REGS2_k127_3138938_31 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000818 125.0
REGS2_k127_3138938_32 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000003032 122.0
REGS2_k127_3138938_33 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000001427 121.0
REGS2_k127_3138938_34 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000001798 102.0
REGS2_k127_3138938_35 Ribonuclease K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000002858 98.0
REGS2_k127_3138938_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000005512 79.0
REGS2_k127_3138938_37 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000001998 71.0
REGS2_k127_3138938_38 NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000006939 69.0
REGS2_k127_3138938_4 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 454.0
REGS2_k127_3138938_5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 430.0
REGS2_k127_3138938_6 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 402.0
REGS2_k127_3138938_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 403.0
REGS2_k127_3138938_8 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 375.0
REGS2_k127_3138938_9 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 378.0
REGS2_k127_3182552_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 7.725e-245 776.0
REGS2_k127_3182552_1 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 3.046e-221 704.0
REGS2_k127_3182552_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 415.0
REGS2_k127_3182552_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000003709 222.0
REGS2_k127_3182552_4 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000001052 173.0
REGS2_k127_3182552_5 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.000000000000000004994 91.0
REGS2_k127_3182552_6 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.00000005678 64.0
REGS2_k127_3182552_7 membrane protein (DUF2078) K08982 - - 0.0000001295 57.0
REGS2_k127_3280182_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1121.0
REGS2_k127_3280182_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 583.0
REGS2_k127_3280182_10 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000002384 186.0
REGS2_k127_3280182_11 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000006248 162.0
REGS2_k127_3280182_12 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000002216 126.0
REGS2_k127_3280182_13 TrpR family protein YerC YecD - - - 0.00000000000000000000001256 104.0
REGS2_k127_3280182_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000003302 101.0
REGS2_k127_3280182_15 Domain of unknown function (DUF4386) - - - 0.00000000000005211 74.0
REGS2_k127_3280182_16 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.00012 49.0
REGS2_k127_3280182_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 297.0
REGS2_k127_3280182_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 294.0
REGS2_k127_3280182_4 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002452 277.0
REGS2_k127_3280182_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002573 283.0
REGS2_k127_3280182_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000018 258.0
REGS2_k127_3280182_7 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000009982 217.0
REGS2_k127_3280182_8 Rifampin ADP-ribosyl transferase K19062 - - 0.000000000000000000000000000000000000000000000000000000000008471 209.0
REGS2_k127_3280182_9 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000001637 207.0
REGS2_k127_3317187_0 domain protein K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 290.0
REGS2_k127_3317187_1 Response regulator receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000176 238.0
REGS2_k127_3317187_2 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000006904 252.0
REGS2_k127_3317187_3 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000003312 237.0
REGS2_k127_3317187_4 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000001046 94.0
REGS2_k127_3349994_0 P-type ATPase K01537 - 3.6.3.8 2.465e-217 707.0
REGS2_k127_3349994_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.679e-206 658.0
REGS2_k127_3349994_10 R3H domain K06346 - - 0.0000000000000000000000000000000000000000000000000000003078 201.0
REGS2_k127_3349994_11 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000001935 209.0
REGS2_k127_3349994_12 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000003388 181.0
REGS2_k127_3349994_13 Membrane protein insertase, YidC Oxa1 family K03217 - - 0.000000000000000000000000000000000000000000002231 178.0
REGS2_k127_3349994_14 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000001106 156.0
REGS2_k127_3349994_15 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000004201 149.0
REGS2_k127_3349994_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001431 116.0
REGS2_k127_3349994_17 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000001612 86.0
REGS2_k127_3349994_18 PFAM FeoA domain K04758 - - 0.000000000000006868 78.0
REGS2_k127_3349994_19 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000003887 72.0
REGS2_k127_3349994_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 440.0
REGS2_k127_3349994_20 Acetyltransferase (GNAT) family - - - 0.00000000002884 72.0
REGS2_k127_3349994_21 gas vesicle protein - - - 0.0002368 47.0
REGS2_k127_3349994_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 394.0
REGS2_k127_3349994_4 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 352.0
REGS2_k127_3349994_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 305.0
REGS2_k127_3349994_6 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001018 280.0
REGS2_k127_3349994_7 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001322 244.0
REGS2_k127_3349994_8 TIGRFAM L-serine dehydratase, iron-sulfur-dependent, beta subunit K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000004859 224.0
REGS2_k127_3349994_9 PDZ DHR GLGF domain protein K08372 - - 0.0000000000000000000000000000000000000000000000000000000006802 218.0
REGS2_k127_3396456_0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 527.0
REGS2_k127_3396456_1 Male sterility protein K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 413.0
REGS2_k127_3396456_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 388.0
REGS2_k127_3396456_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000002474 221.0
REGS2_k127_3396456_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133 0.000000000000000000000000000000000000000000000000000000001983 213.0
REGS2_k127_3396456_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000005877 217.0
REGS2_k127_3396456_6 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000001681 198.0
REGS2_k127_3396456_7 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000001795 175.0
REGS2_k127_3396456_8 Glycosyl transferases group 1 - - - 0.0000000000000000000009672 106.0
REGS2_k127_3555171_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1103.0
REGS2_k127_3555171_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 8.533e-205 647.0
REGS2_k127_3555171_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 372.0
REGS2_k127_3555171_3 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001283 295.0
REGS2_k127_3555171_4 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.000000000000000000000000000000000000000008668 166.0
REGS2_k127_3602342_0 Methyltransferase K00563 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000004234 267.0
REGS2_k127_3602342_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000003964 250.0
REGS2_k127_3602342_10 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000433 150.0
REGS2_k127_3602342_11 denitrification pathway - - - 0.000000000000000000000000000000001731 139.0
REGS2_k127_3602342_12 - - - - 0.0000000000000000000000000000002363 138.0
REGS2_k127_3602342_13 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000008021 138.0
REGS2_k127_3602342_14 FMN binding - - - 0.000000000000000000000000007379 119.0
REGS2_k127_3602342_15 denitrification pathway - - - 0.000000000000000000007189 109.0
REGS2_k127_3602342_16 PFAM Transglycosylase-associated protein - - - 0.0000000000000000003408 91.0
REGS2_k127_3602342_17 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000001918 83.0
REGS2_k127_3602342_18 integral membrane protein - - - 0.0000000000007072 76.0
REGS2_k127_3602342_19 denitrification pathway - - - 0.000000000001353 79.0
REGS2_k127_3602342_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07651 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000004877 250.0
REGS2_k127_3602342_20 - - - - 0.000000000008215 75.0
REGS2_k127_3602342_3 Transcriptional regulatory protein, C terminal K02483,K07658 - - 0.000000000000000000000000000000000000000000000000000000000000007789 224.0
REGS2_k127_3602342_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000005571 201.0
REGS2_k127_3602342_5 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000002764 189.0
REGS2_k127_3602342_6 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000002536 179.0
REGS2_k127_3602342_7 Belongs to the MsrB Met sulfoxide reductase family - - - 0.00000000000000000000000000000000000000000000003309 173.0
REGS2_k127_3602342_8 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000007165 181.0
REGS2_k127_3602342_9 membrane - - - 0.000000000000000000000000000000000000002734 154.0
REGS2_k127_3721958_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 9.757e-221 698.0
REGS2_k127_3721958_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.402e-217 691.0
REGS2_k127_3721958_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001317 262.0
REGS2_k127_3721958_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000004674 249.0
REGS2_k127_3721958_12 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
REGS2_k127_3721958_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000002087 233.0
REGS2_k127_3721958_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000001492 222.0
REGS2_k127_3721958_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000002057 228.0
REGS2_k127_3721958_16 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000000000000000000006478 218.0
REGS2_k127_3721958_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000001455 201.0
REGS2_k127_3721958_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000001658 192.0
REGS2_k127_3721958_19 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.0000000000000000000000000000000000000000000003353 183.0
REGS2_k127_3721958_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 8.022e-217 681.0
REGS2_k127_3721958_20 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000007076 168.0
REGS2_k127_3721958_21 PFAM CBS domain - - - 0.000000000000000000000000000000000000001067 153.0
REGS2_k127_3721958_22 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000006721 151.0
REGS2_k127_3721958_23 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000000000647 141.0
REGS2_k127_3721958_24 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000002359 134.0
REGS2_k127_3721958_25 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001264 78.0
REGS2_k127_3721958_26 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000005343 73.0
REGS2_k127_3721958_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000003393 74.0
REGS2_k127_3721958_28 ATP synthase subunit C K02124 - - 0.0000168 51.0
REGS2_k127_3721958_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 472.0
REGS2_k127_3721958_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 362.0
REGS2_k127_3721958_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 373.0
REGS2_k127_3721958_6 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 370.0
REGS2_k127_3721958_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 334.0
REGS2_k127_3721958_8 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 291.0
REGS2_k127_3721958_9 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009885 292.0
REGS2_k127_3745741_0 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 6.368e-196 635.0
REGS2_k127_3745741_1 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 634.0
REGS2_k127_3745741_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000356 165.0
REGS2_k127_3745741_11 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000001568 148.0
REGS2_k127_3745741_12 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000002037 147.0
REGS2_k127_3745741_13 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000002524 83.0
REGS2_k127_3745741_14 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000004146 77.0
REGS2_k127_3745741_2 PFAM 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 387.0
REGS2_k127_3745741_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 356.0
REGS2_k127_3745741_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 339.0
REGS2_k127_3745741_5 DAK2 domain fusion protein YloV K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000381 280.0
REGS2_k127_3745741_6 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000005285 243.0
REGS2_k127_3745741_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000493 197.0
REGS2_k127_3745741_8 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000007325 201.0
REGS2_k127_3745741_9 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000002834 195.0
REGS2_k127_395269_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.087e-206 657.0
REGS2_k127_395269_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 539.0
REGS2_k127_395269_10 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0001612 50.0
REGS2_k127_395269_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
REGS2_k127_395269_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004123 275.0
REGS2_k127_395269_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002297 265.0
REGS2_k127_395269_5 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007742 263.0
REGS2_k127_395269_6 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000005913 244.0
REGS2_k127_395269_7 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000001311 221.0
REGS2_k127_395269_8 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000009917 209.0
REGS2_k127_395269_9 ACT domain protein - - - 0.0000000000000000000000000000000000001715 145.0
REGS2_k127_4017455_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 435.0
REGS2_k127_4017455_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 427.0
REGS2_k127_4017455_10 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000001743 201.0
REGS2_k127_4017455_11 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.00000000000000000000000000000002388 136.0
REGS2_k127_4017455_2 glycine betaine transport K05845 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0033554,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0104004 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 320.0
REGS2_k127_4017455_3 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 313.0
REGS2_k127_4017455_4 Phosphorylase superfamily K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 305.0
REGS2_k127_4017455_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005162 287.0
REGS2_k127_4017455_6 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002424 286.0
REGS2_k127_4017455_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000004639 256.0
REGS2_k127_4017455_8 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002161 260.0
REGS2_k127_4017455_9 NADH dehydrogenase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000006329 203.0
REGS2_k127_4045652_0 ABC transporter, ATP-binding protein K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 577.0
REGS2_k127_4045652_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 474.0
REGS2_k127_4045652_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 307.0
REGS2_k127_4045652_11 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 293.0
REGS2_k127_4045652_12 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 293.0
REGS2_k127_4045652_13 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
REGS2_k127_4045652_14 Cell cycle protein K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002905 287.0
REGS2_k127_4045652_15 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005044 279.0
REGS2_k127_4045652_16 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000938 138.0
REGS2_k127_4045652_17 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000966 130.0
REGS2_k127_4045652_18 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000192 127.0
REGS2_k127_4045652_19 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000001486 111.0
REGS2_k127_4045652_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 471.0
REGS2_k127_4045652_20 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000005648 94.0
REGS2_k127_4045652_3 Belongs to the MurCDEF family. MurE subfamily K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 445.0
REGS2_k127_4045652_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 383.0
REGS2_k127_4045652_5 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 397.0
REGS2_k127_4045652_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 371.0
REGS2_k127_4045652_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 357.0
REGS2_k127_4045652_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 346.0
REGS2_k127_4045652_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 355.0
REGS2_k127_411715_0 Two component signalling adaptor domain K03407,K13490 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 471.0
REGS2_k127_411715_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 290.0
REGS2_k127_411715_2 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000003248 224.0
REGS2_k127_411715_3 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000003073 209.0
REGS2_k127_411715_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.000000000000000000000000000293 123.0
REGS2_k127_411715_5 PFAM CheW domain protein K03408 - - 0.00000000000000007555 92.0
REGS2_k127_411715_6 PFAM CheW domain protein K03408 - - 0.0000000000000001546 91.0
REGS2_k127_411715_7 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000005161 83.0
REGS2_k127_4162891_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 1.46e-261 833.0
REGS2_k127_4162891_1 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 551.0
REGS2_k127_4162891_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000005737 164.0
REGS2_k127_4162891_3 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000001472 121.0
REGS2_k127_4251881_0 Radical SAM K22226 - - 2.817e-219 687.0
REGS2_k127_4251881_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 591.0
REGS2_k127_4251881_10 Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005711 256.0
REGS2_k127_4251881_11 heme exporter protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000000001156 224.0
REGS2_k127_4251881_12 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000485 221.0
REGS2_k127_4251881_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
REGS2_k127_4251881_14 PFAM helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000217 146.0
REGS2_k127_4251881_15 sequence-specific DNA binding - - - 0.00000000000000000000000003915 119.0
REGS2_k127_4251881_16 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000006134 104.0
REGS2_k127_4251881_17 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000005019 72.0
REGS2_k127_4251881_18 - - - - 0.00000000002067 66.0
REGS2_k127_4251881_19 PFAM Cytochrome c assembly protein - - - 0.0000000004297 70.0
REGS2_k127_4251881_2 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 582.0
REGS2_k127_4251881_3 biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 550.0
REGS2_k127_4251881_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 467.0
REGS2_k127_4251881_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 423.0
REGS2_k127_4251881_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 322.0
REGS2_k127_4251881_7 PFAM ABC transporter K01990,K02193,K09697 - 3.6.3.41,3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 319.0
REGS2_k127_4251881_8 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001114 290.0
REGS2_k127_4251881_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000882 267.0
REGS2_k127_427531_0 PFAM Glycosyl transferase, group 1 K06338,K12995 - 2.4.1.348 0.00000000000000000000000000000000000000000000000000000000000000000000000001154 264.0
REGS2_k127_427531_1 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 261.0
REGS2_k127_427531_2 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.000000000000000000000000000000000000000000000000000001369 196.0
REGS2_k127_427531_3 O-Antigen ligase - - - 0.00000001675 68.0
REGS2_k127_427531_4 Tetratricopeptide repeat - - - 0.00000008827 63.0
REGS2_k127_4298003_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 505.0
REGS2_k127_4298003_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 372.0
REGS2_k127_4298003_2 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 370.0
REGS2_k127_4298003_3 Transaldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 353.0
REGS2_k127_4298003_4 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002283 297.0
REGS2_k127_4298003_5 2-phosphoglycerate kinase K05715 - - 0.000000000000000000000000000000000000000000000000000000000000001911 235.0
REGS2_k127_4298003_6 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000009059 209.0
REGS2_k127_4552214_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.138e-237 755.0
REGS2_k127_4552214_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 363.0
REGS2_k127_4552214_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 334.0
REGS2_k127_4552214_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000547 254.0
REGS2_k127_4552214_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000001115 125.0
REGS2_k127_4552214_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000001572 118.0
REGS2_k127_4583471_0 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 305.0
REGS2_k127_4583471_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
REGS2_k127_4583471_10 branched-chain amino acid - - - 0.000000000000001158 89.0
REGS2_k127_4583471_2 FAD binding domain K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001072 290.0
REGS2_k127_4583471_3 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005402 286.0
REGS2_k127_4583471_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003272 249.0
REGS2_k127_4583471_5 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000005434 245.0
REGS2_k127_4583471_6 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000000000000000000000000000000000000000393 204.0
REGS2_k127_4583471_7 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000005938 170.0
REGS2_k127_4583471_8 PFAM AzlC family protein - - - 0.000000000000000000000000000000000006466 154.0
REGS2_k127_4583471_9 - - - - 0.00000000000000006792 84.0
REGS2_k127_4653918_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 609.0
REGS2_k127_4653918_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 489.0
REGS2_k127_4653918_2 Peptidase family M28 - - - 0.000000000000000000007447 105.0
REGS2_k127_4653918_3 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000004927 93.0
REGS2_k127_4653918_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000002333 67.0
REGS2_k127_4656976_0 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 3.526e-318 996.0
REGS2_k127_4656976_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.42e-210 701.0
REGS2_k127_4656976_10 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000002542 209.0
REGS2_k127_4656976_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000007177 188.0
REGS2_k127_4656976_12 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000009783 177.0
REGS2_k127_4656976_13 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate - - - 0.000000000000000000000000000000000000000003616 175.0
REGS2_k127_4656976_14 LICD family K07271 - - 0.00000000000000000000000000000000000000006847 175.0
REGS2_k127_4656976_15 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000003173 162.0
REGS2_k127_4656976_16 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000001249 160.0
REGS2_k127_4656976_17 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000001124 141.0
REGS2_k127_4656976_18 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000675 132.0
REGS2_k127_4656976_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02658 - - 0.00000000000000000000000000003312 121.0
REGS2_k127_4656976_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 4.147e-208 661.0
REGS2_k127_4656976_20 Glycosyltransferase like family 2 K13002 - - 0.0000000000000000000000000002633 132.0
REGS2_k127_4656976_21 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000009568 124.0
REGS2_k127_4656976_22 RF-1 domain - - - 0.00000000000000000000004737 110.0
REGS2_k127_4656976_23 small multidrug export protein - - - 0.00000000000000000001837 96.0
REGS2_k127_4656976_24 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000003072 87.0
REGS2_k127_4656976_25 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000004243 94.0
REGS2_k127_4656976_26 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000001737 77.0
REGS2_k127_4656976_27 regulatory protein, arsR K07755,K21903 - 2.1.1.137 0.000000000000001979 81.0
REGS2_k127_4656976_29 Polysaccharide biosynthesis protein - - - 0.000009171 58.0
REGS2_k127_4656976_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 371.0
REGS2_k127_4656976_30 -O-antigen K18814 - - 0.00001001 59.0
REGS2_k127_4656976_4 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 344.0
REGS2_k127_4656976_5 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 293.0
REGS2_k127_4656976_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004762 258.0
REGS2_k127_4656976_7 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000009921 254.0
REGS2_k127_4656976_8 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000048 235.0
REGS2_k127_4656976_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000001553 221.0
REGS2_k127_4682540_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 510.0
REGS2_k127_4682540_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 490.0
REGS2_k127_4682540_2 alcohol dehydrogenase K13953,K18382 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 410.0
REGS2_k127_4682540_3 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 315.0
REGS2_k127_4682540_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000001326 229.0
REGS2_k127_4682540_5 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000002423 188.0
REGS2_k127_4682540_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000005083 179.0
REGS2_k127_4682540_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000004268 167.0
REGS2_k127_4682540_8 Acetyltransferase K03824 - - 0.00000000000000000000000000000118 131.0
REGS2_k127_4682540_9 COG0501 Zn-dependent protease with chaperone function K03799 - - 0.000000002143 70.0
REGS2_k127_4817148_0 Conserved region in glutamate synthase - - - 2.037e-250 784.0
REGS2_k127_4817148_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 521.0
REGS2_k127_4817148_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 327.0
REGS2_k127_4817148_3 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001536 280.0
REGS2_k127_4817148_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009458 272.0
REGS2_k127_4817148_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000006015 239.0
REGS2_k127_4817148_6 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000002298 64.0
REGS2_k127_4817148_7 PFAM TOBE domain K02019 - - 0.000002317 53.0
REGS2_k127_4940234_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.406e-224 707.0
REGS2_k127_4940234_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 8.963e-221 698.0
REGS2_k127_4940234_10 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 261.0
REGS2_k127_4940234_11 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
REGS2_k127_4940234_12 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.00000000000000000000000000002237 134.0
REGS2_k127_4940234_13 - - - - 0.00000000000000000000005294 108.0
REGS2_k127_4940234_15 hydrolase, family 25 - - - 0.00000000000006766 85.0
REGS2_k127_4940234_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.914e-215 677.0
REGS2_k127_4940234_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.053e-206 665.0
REGS2_k127_4940234_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 543.0
REGS2_k127_4940234_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 500.0
REGS2_k127_4940234_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 465.0
REGS2_k127_4940234_7 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 440.0
REGS2_k127_4940234_8 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 394.0
REGS2_k127_4940234_9 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 388.0
REGS2_k127_5039604_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.794e-286 893.0
REGS2_k127_5039604_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.587e-244 764.0
REGS2_k127_5039604_10 SMART tyrosine protein kinase K08884 - 2.7.11.1 0.00000002573 63.0
REGS2_k127_5039604_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 6.044e-212 674.0
REGS2_k127_5039604_3 PFAM Signal transduction histidine kinase, osmosensitive K channel sensor, N-terminal K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 372.0
REGS2_k127_5039604_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003333 250.0
REGS2_k127_5039604_5 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000008536 234.0
REGS2_k127_5039604_6 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000002535 219.0
REGS2_k127_5039604_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000009022 183.0
REGS2_k127_5039604_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000002161 178.0
REGS2_k127_5039604_9 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000003162 86.0
REGS2_k127_5157889_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.231e-230 728.0
REGS2_k127_5157889_1 DnaQ family exonuclease DinG family helicase K03722 - 3.6.4.12 1.274e-226 735.0
REGS2_k127_5157889_10 WYL domain K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000004109 91.0
REGS2_k127_5157889_11 Nitrous oxide-stimulated promoter - - - 0.00000000000001218 79.0
REGS2_k127_5157889_12 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.00000000000001228 82.0
REGS2_k127_5157889_13 PFAM Peptidase family M28 - - - 0.0000000000003055 83.0
REGS2_k127_5157889_14 PFAM SpoVT AbrB like domain K07172 - - 0.000000000005092 72.0
REGS2_k127_5157889_15 - - - - 0.00000005679 63.0
REGS2_k127_5157889_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000003172 195.0
REGS2_k127_5157889_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000002487 187.0
REGS2_k127_5157889_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000006183 152.0
REGS2_k127_5157889_5 domain, Protein - - - 0.000000000000000000000000000007992 137.0
REGS2_k127_5157889_6 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000001654 129.0
REGS2_k127_5157889_7 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000879 119.0
REGS2_k127_5157889_8 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.0000000000000000001036 103.0
REGS2_k127_5157889_9 Protein of unknown function (DUF1461) - - - 0.000000000000000003073 94.0
REGS2_k127_5207047_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0 1086.0
REGS2_k127_5207047_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.654e-292 921.0
REGS2_k127_5207047_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 385.0
REGS2_k127_5207047_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 377.0
REGS2_k127_5207047_12 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 331.0
REGS2_k127_5207047_13 RNA polymerase sigma-70 factor, sigma-B F G subfamily K03090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 295.0
REGS2_k127_5207047_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 291.0
REGS2_k127_5207047_15 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
REGS2_k127_5207047_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000002132 246.0
REGS2_k127_5207047_17 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000002332 242.0
REGS2_k127_5207047_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000008457 207.0
REGS2_k127_5207047_19 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000001256 198.0
REGS2_k127_5207047_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.017e-275 868.0
REGS2_k127_5207047_20 domain protein - - - 0.000000000000000000000000000000000000000000000000000001633 198.0
REGS2_k127_5207047_21 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000008843 182.0
REGS2_k127_5207047_22 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000005002 158.0
REGS2_k127_5207047_23 HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668 K07015 - - 0.000000000000000000000000000000000000004305 152.0
REGS2_k127_5207047_24 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000001863 154.0
REGS2_k127_5207047_25 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000007185 156.0
REGS2_k127_5207047_26 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.0000000000000000000000000000000000007985 146.0
REGS2_k127_5207047_27 PFAM Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000001973 134.0
REGS2_k127_5207047_28 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000001262 138.0
REGS2_k127_5207047_29 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000185 119.0
REGS2_k127_5207047_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.903e-217 687.0
REGS2_k127_5207047_30 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000001665 98.0
REGS2_k127_5207047_32 Preprotein translocase subunit K03210 - - 0.0000000000001731 74.0
REGS2_k127_5207047_33 Desulfoferrodoxin K05919 - 1.15.1.2 0.000000000002604 76.0
REGS2_k127_5207047_34 Bacterial protein of unknown function (DUF948) - - - 0.000003341 55.0
REGS2_k127_5207047_35 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000005058 57.0
REGS2_k127_5207047_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.982e-216 686.0
REGS2_k127_5207047_5 type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 584.0
REGS2_k127_5207047_6 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 548.0
REGS2_k127_5207047_7 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 514.0
REGS2_k127_5207047_8 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 490.0
REGS2_k127_5207047_9 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 431.0
REGS2_k127_5428961_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 486.0
REGS2_k127_5428961_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000002065 235.0
REGS2_k127_5428961_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000006561 199.0
REGS2_k127_5428961_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001632 140.0
REGS2_k127_5428961_4 Hydrolase HD family - - - 0.000000000000000000000000000011 129.0
REGS2_k127_5428961_5 Cell envelope-related transcriptional attenuator domain - - - 0.000004843 59.0
REGS2_k127_5495599_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 580.0
REGS2_k127_5495599_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 422.0
REGS2_k127_5495599_10 denitrification pathway - - - 0.000000001312 70.0
REGS2_k127_5495599_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03116,K03117 - - 0.000000006318 62.0
REGS2_k127_5495599_12 STAS domain K20978 - - 0.00000001854 61.0
REGS2_k127_5495599_13 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000002145 61.0
REGS2_k127_5495599_14 cytochrome complex assembly K02200,K04018 - - 0.00000624 57.0
REGS2_k127_5495599_2 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 303.0
REGS2_k127_5495599_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
REGS2_k127_5495599_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000002502 195.0
REGS2_k127_5495599_5 PFAM Metal-dependent phosphohydrolase, HD K06951 - - 0.00000000000000000000000000000000000000000000001864 176.0
REGS2_k127_5495599_6 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000001851 150.0
REGS2_k127_5495599_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000004648 131.0
REGS2_k127_5495599_8 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000003452 111.0
REGS2_k127_5495599_9 denitrification pathway - - - 0.00000000000000000005642 102.0
REGS2_k127_5528375_0 Sulfate permease family K03321 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 606.0
REGS2_k127_5528375_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 411.0
REGS2_k127_5528375_10 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000000000000001043 105.0
REGS2_k127_5528375_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000004712 79.0
REGS2_k127_5528375_12 PFAM DNA polymerase, beta domain protein region K07075 - - 0.00000000000003436 81.0
REGS2_k127_5528375_2 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 GO:0001522,GO:0003674,GO:0003824,GO:0004730,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016043,GO:0016070,GO:0016787,GO:0016798,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0030145,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0090304,GO:1901360 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 351.0
REGS2_k127_5528375_3 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 320.0
REGS2_k127_5528375_4 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000249 192.0
REGS2_k127_5528375_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000004557 161.0
REGS2_k127_5528375_6 Condensation domain - - - 0.0000000000000000000000000000000000000004822 165.0
REGS2_k127_5528375_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000006276 130.0
REGS2_k127_5528375_9 Type IV pili methyl-accepting chemotaxis transducer N-term K07673 - 2.7.13.3 0.0000000000000000000000009863 120.0
REGS2_k127_5607462_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 399.0
REGS2_k127_5607462_1 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 354.0
REGS2_k127_5607462_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 333.0
REGS2_k127_5607462_3 phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001736 268.0
REGS2_k127_5607462_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000004509 196.0
REGS2_k127_5607462_5 copper ion binding K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000002432 183.0
REGS2_k127_5607462_6 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.00000000000000000000000000009705 123.0
REGS2_k127_5607462_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000001577 124.0
REGS2_k127_5607462_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.00000000000000005692 88.0
REGS2_k127_5659017_0 COG2217 Cation transport ATPase K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 566.0
REGS2_k127_5659017_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006219 261.0
REGS2_k127_5659017_2 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000000000000000005661 191.0
REGS2_k127_5659017_3 regulatory protein, arsR K21903 - - 0.000000000000000000000003887 106.0
REGS2_k127_5680906_0 Elongation factor SelB winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 574.0
REGS2_k127_5680906_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 455.0
REGS2_k127_5680906_10 DsrE/DsrF-like family - - - 0.0000000000000000000000002797 109.0
REGS2_k127_5680906_11 Protein of unknown function (DUF501) K09009 - - 0.00000000000000000002775 101.0
REGS2_k127_5680906_12 protein related to plant photosystem II stability assembly factor - - - 0.0000000008486 70.0
REGS2_k127_5680906_13 Methionine synthase B12-binding module cap domain protein - - - 0.000000002221 70.0
REGS2_k127_5680906_14 Tetratricopeptide TPR_2 repeat protein - - - 0.000000002291 70.0
REGS2_k127_5680906_15 cell cycle K05589,K12065,K13052 - - 0.00000003739 59.0
REGS2_k127_5680906_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 347.0
REGS2_k127_5680906_3 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006727 267.0
REGS2_k127_5680906_4 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000007861 233.0
REGS2_k127_5680906_5 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000004081 221.0
REGS2_k127_5680906_6 protein histidine kinase activity K02484,K07640,K07643,K07645,K07649,K19609 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001381 204.0
REGS2_k127_5680906_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000006735 192.0
REGS2_k127_5680906_8 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000001557 139.0
REGS2_k127_5680906_9 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000005025 124.0
REGS2_k127_569081_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1489.0
REGS2_k127_569081_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1090.0
REGS2_k127_569081_10 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 324.0
REGS2_k127_569081_11 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 314.0
REGS2_k127_569081_12 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002974 268.0
REGS2_k127_569081_13 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001681 246.0
REGS2_k127_569081_14 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000121 240.0
REGS2_k127_569081_15 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000001336 242.0
REGS2_k127_569081_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005951 244.0
REGS2_k127_569081_17 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000007252 228.0
REGS2_k127_569081_18 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000348 202.0
REGS2_k127_569081_19 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000001515 213.0
REGS2_k127_569081_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 504.0
REGS2_k127_569081_20 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000000000000000000000000000000000000000000001095 205.0
REGS2_k127_569081_21 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000007892 184.0
REGS2_k127_569081_22 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000001285 156.0
REGS2_k127_569081_23 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000001184 139.0
REGS2_k127_569081_24 cheY-homologous receiver domain K11443 - - 0.00000000000000000000000000000000001638 139.0
REGS2_k127_569081_25 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.0000000000000000000000000000000007108 136.0
REGS2_k127_569081_26 Rubrerythrin K19824 - - 0.00000000000000000000000000005859 127.0
REGS2_k127_569081_27 integration host factor - - - 0.0000000000000000000000000007615 117.0
REGS2_k127_569081_28 DivIVA domain protein K04074 - - 0.000000000000000000000000001256 123.0
REGS2_k127_569081_29 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000221 112.0
REGS2_k127_569081_3 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 461.0
REGS2_k127_569081_30 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000671 94.0
REGS2_k127_569081_31 DUF167 K09131 - - 0.000000000000001459 86.0
REGS2_k127_569081_32 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000003075 70.0
REGS2_k127_569081_33 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.000000001351 63.0
REGS2_k127_569081_34 Phospholipase_D-nuclease N-terminal - - - 0.000001311 56.0
REGS2_k127_569081_35 YGGT family K02221 - - 0.00004217 53.0
REGS2_k127_569081_4 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 385.0
REGS2_k127_569081_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 385.0
REGS2_k127_569081_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 358.0
REGS2_k127_569081_7 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 348.0
REGS2_k127_569081_8 abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 344.0
REGS2_k127_569081_9 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 341.0
REGS2_k127_5756491_0 PFAM Glycosyl transferase family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 297.0
REGS2_k127_5756491_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000005319 158.0
REGS2_k127_5756491_2 response regulator - - - 0.00000000000000000000000006203 118.0
REGS2_k127_5756491_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000118 91.0
REGS2_k127_5756491_4 Domain of unknown function DUF11 - - - 0.0000000000008883 83.0
REGS2_k127_5756491_5 Bacterial protein of unknown function (DUF916) - - - 0.000002753 59.0
REGS2_k127_5808391_0 Periplasmic binding protein domain K10543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 434.0
REGS2_k127_5808391_1 Branched-chain amino acid transport system / permease component K10544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 398.0
REGS2_k127_5808391_10 - K21495 - - 0.0005539 47.0
REGS2_k127_5808391_2 Short-chain dehydrogenase reductase sdr K00059,K20900 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0030246,GO:0042221,GO:0044238,GO:0047880,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 1.1.1.100,1.1.1.403 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
REGS2_k127_5808391_3 ABC transporter K02056,K10545 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 302.0
REGS2_k127_5808391_4 Ribose/Galactose Isomerase K01808 GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000003143 229.0
REGS2_k127_5808391_5 PFAM Dak kinase K00863,K05878,K20902 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0030246,GO:0042221,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 2.7.1.121,2.7.1.210,2.7.1.28,2.7.1.29,4.6.1.15 0.0000000000000000000000000000000000000000000000000003909 189.0
REGS2_k127_5808391_6 PFAM AAA-4 family protein K03655 - 3.6.4.12 0.0000000000000000000000000000000000000001344 165.0
REGS2_k127_5808391_7 - - - - 0.00000000000001263 83.0
REGS2_k127_5808391_8 PIN domain - - - 0.00000000000004525 77.0
REGS2_k127_5808391_9 Protein tyrosine kinase - - - 0.0000000003762 70.0
REGS2_k127_5862393_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.417e-302 941.0
REGS2_k127_5862393_1 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001169 288.0
REGS2_k127_5862393_10 - - - - 0.000000000001748 75.0
REGS2_k127_5862393_11 Short C-terminal domain K08982 - - 0.0005322 47.0
REGS2_k127_5862393_2 pfam abc1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004822 257.0
REGS2_k127_5862393_3 short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003342 250.0
REGS2_k127_5862393_4 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000002553 194.0
REGS2_k127_5862393_5 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000006388 152.0
REGS2_k127_5862393_6 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000004355 134.0
REGS2_k127_5862393_7 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000002532 131.0
REGS2_k127_5862393_8 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000003289 79.0
REGS2_k127_5929603_0 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 2.774e-268 850.0
REGS2_k127_5929603_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 580.0
REGS2_k127_5929603_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000173 232.0
REGS2_k127_5929603_11 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000004144 233.0
REGS2_k127_5929603_12 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000005343 184.0
REGS2_k127_5929603_13 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000002544 181.0
REGS2_k127_5929603_14 Winged helix-turn-helix DNA-binding K00852,K16328 - 2.7.1.15,2.7.1.83 0.0000000000000000000000000000000000000000000005699 178.0
REGS2_k127_5929603_15 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000001191 189.0
REGS2_k127_5929603_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000004557 159.0
REGS2_k127_5929603_17 EamA-like transporter family - - - 0.00000000000000000000000000000000001811 146.0
REGS2_k127_5929603_18 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000005485 142.0
REGS2_k127_5929603_19 N-terminal domain of toast_rack, DUF2154 - - - 0.0000000000000000000000000000005131 132.0
REGS2_k127_5929603_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 514.0
REGS2_k127_5929603_20 - - - - 0.0000000000000000000000000626 116.0
REGS2_k127_5929603_21 RmlD substrate binding domain - - - 0.0000000000000000000000002991 118.0
REGS2_k127_5929603_22 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000006915 121.0
REGS2_k127_5929603_23 peptidase U32 - - - 0.0000000000003057 72.0
REGS2_k127_5929603_24 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000004596 79.0
REGS2_k127_5929603_26 - - - - 0.0000000001227 71.0
REGS2_k127_5929603_3 PFAM LOR SDH bifunctional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 437.0
REGS2_k127_5929603_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 413.0
REGS2_k127_5929603_5 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 334.0
REGS2_k127_5929603_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 326.0
REGS2_k127_5929603_7 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002561 293.0
REGS2_k127_5929603_8 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000003045 270.0
REGS2_k127_5929603_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004501 241.0
REGS2_k127_6000698_0 metallopeptidase activity K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 515.0
REGS2_k127_6000698_1 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 477.0
REGS2_k127_6000698_10 (Hpt) domain - - - 0.0000000000000004392 85.0
REGS2_k127_6000698_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 322.0
REGS2_k127_6000698_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 297.0
REGS2_k127_6000698_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004538 269.0
REGS2_k127_6000698_5 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001047 261.0
REGS2_k127_6000698_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000002813 227.0
REGS2_k127_6000698_7 NLP P60 protein K21471 - - 0.000000000000000000000000000000000000000000215 174.0
REGS2_k127_6000698_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000007775 133.0
REGS2_k127_6000698_9 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000142 123.0
REGS2_k127_6122245_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.405e-194 615.0
REGS2_k127_6122245_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000000005705 175.0
REGS2_k127_6122245_2 PFAM secretion protein HlyD family protein K01993 - - 0.000000000003798 78.0
REGS2_k127_6122245_3 Belongs to the peptidase S8 family - - - 0.00002658 55.0
REGS2_k127_6178485_0 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 292.0
REGS2_k127_6178485_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005178 280.0
REGS2_k127_6178485_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007905 284.0
REGS2_k127_6220257_0 Multicopper oxidase - - - 0.0 1119.0
REGS2_k127_6220257_1 D-Lysine 5,6-aminomutase alpha subunit K17898 - 5.4.3.5 0.0 1042.0
REGS2_k127_6220257_10 amino acid activation for nonribosomal peptide biosynthetic process K02406,K19693 - - 0.000000000000000000004532 111.0
REGS2_k127_6220257_11 belongs to the nudix hydrolase family - - - 0.00000000000000000001473 100.0
REGS2_k127_6220257_12 Serine aminopeptidase, S33 - - - 0.00000000000000001029 95.0
REGS2_k127_6220257_13 PilT protein domain protein - - - 0.000000000004315 72.0
REGS2_k127_6220257_14 Prepilin-type cleavage methylation N-terminal domain protein K02650 - - 0.00000000003291 70.0
REGS2_k127_6220257_15 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000001308 59.0
REGS2_k127_6220257_16 protein conserved in bacteria K09790 - - 0.00001992 49.0
REGS2_k127_6220257_17 zinc-ribbon domain - - - 0.00002793 56.0
REGS2_k127_6220257_2 Pyridoxal-phosphate dependent enzyme K21400 - 2.3.1.263 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 599.0
REGS2_k127_6220257_3 MutL protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 374.0
REGS2_k127_6220257_4 Dihydrodipicolinate reductase, N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 348.0
REGS2_k127_6220257_5 Alanine racemase, N-terminal domain K21898 - 5.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 307.0
REGS2_k127_6220257_6 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000002415 149.0
REGS2_k127_6220257_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000006985 133.0
REGS2_k127_6220257_8 D-ornithine 4,5-aminomutase alpha-subunit K17899 - 5.4.3.5 0.000000000000000000000000007948 113.0
REGS2_k127_6220257_9 - K21399 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263 0.0000000000000000000001036 101.0
REGS2_k127_6240721_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.612e-207 655.0
REGS2_k127_6240721_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070,K03789,K14742 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004596,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006473,GO:0006474,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008999,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0030312,GO:0031365,GO:0032991,GO:0034212,GO:0034470,GO:0034641,GO:0034660,GO:0036211,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051604,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.128,2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 481.0
REGS2_k127_6240721_2 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000002312 240.0
REGS2_k127_6240721_3 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000007604 172.0
REGS2_k127_6240721_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000002342 163.0
REGS2_k127_6240721_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000001977 147.0
REGS2_k127_6240721_6 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000000000001982 137.0
REGS2_k127_6449206_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 397.0
REGS2_k127_6449206_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 334.0
REGS2_k127_6449206_2 RQC K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 331.0
REGS2_k127_6449206_3 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000002287 188.0
REGS2_k127_6449206_4 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000005319 140.0
REGS2_k127_6449206_5 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000002129 126.0
REGS2_k127_6449206_6 - - - - 0.0000000000000002034 93.0
REGS2_k127_6449206_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000002278 76.0
REGS2_k127_6449206_8 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000239 75.0
REGS2_k127_6529524_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 394.0
REGS2_k127_6529524_1 Cysteine desulfurase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 328.0
REGS2_k127_6529524_10 Molybdopterin biosynthesis K03750 - 2.10.1.1 0.000004217 51.0
REGS2_k127_6529524_11 - - - - 0.000005866 54.0
REGS2_k127_6529524_2 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000004706 214.0
REGS2_k127_6529524_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000008672 190.0
REGS2_k127_6529524_4 TIGRFAM molybdenum cofactor synthesis - - - 0.00000000000000000000000000000000000000000000001744 175.0
REGS2_k127_6529524_5 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000000000000000002472 145.0
REGS2_k127_6529524_6 Cytochrome b subunit of formate dehydrogenase-like protein - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.000000000000000000000001043 118.0
REGS2_k127_6529524_7 Prokaryotic cytochrome b561 - - - 0.000000000000000000000009803 115.0
REGS2_k127_6529524_8 denitrification pathway - - - 0.000000000000000004647 98.0
REGS2_k127_6529524_9 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.00000000000000008065 90.0
REGS2_k127_6554124_0 GTP-binding protein TypA K06207 - - 3.737e-290 902.0
REGS2_k127_6554124_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.481e-287 914.0
REGS2_k127_6554124_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 465.0
REGS2_k127_6554124_11 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 448.0
REGS2_k127_6554124_12 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 448.0
REGS2_k127_6554124_13 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 414.0
REGS2_k127_6554124_14 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 375.0
REGS2_k127_6554124_15 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 374.0
REGS2_k127_6554124_16 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 357.0
REGS2_k127_6554124_17 histidine kinase DNA gyrase B K07704 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 354.0
REGS2_k127_6554124_18 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 352.0
REGS2_k127_6554124_19 Arginase family K01479,K01480 - 3.5.3.11,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 338.0
REGS2_k127_6554124_2 ABC transporter, transmembrane region K06147 - - 6.267e-256 829.0
REGS2_k127_6554124_20 TipAS antibiotic-recognition domain K21744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 301.0
REGS2_k127_6554124_21 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 297.0
REGS2_k127_6554124_22 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
REGS2_k127_6554124_23 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000239 297.0
REGS2_k127_6554124_24 response regulator receiver K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
REGS2_k127_6554124_25 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001967 275.0
REGS2_k127_6554124_26 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001302 279.0
REGS2_k127_6554124_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007691 259.0
REGS2_k127_6554124_28 4Fe-4S ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000001253 252.0
REGS2_k127_6554124_29 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003896 258.0
REGS2_k127_6554124_3 ABC transporter, transmembrane region K06147 - - 1.208e-246 781.0
REGS2_k127_6554124_30 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000002778 207.0
REGS2_k127_6554124_31 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001935 215.0
REGS2_k127_6554124_32 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000464 217.0
REGS2_k127_6554124_33 QueT transporter - - - 0.0000000000000000000000000000000000000000000000000004525 192.0
REGS2_k127_6554124_34 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000006962 191.0
REGS2_k127_6554124_35 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000007431 188.0
REGS2_k127_6554124_36 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000001325 204.0
REGS2_k127_6554124_37 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000001674 191.0
REGS2_k127_6554124_38 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000005759 179.0
REGS2_k127_6554124_39 - - - - 0.00000000000000000000000000000000000000000001445 167.0
REGS2_k127_6554124_4 HypF finger K04656 - - 2.207e-229 737.0
REGS2_k127_6554124_40 heat shock protein binding - - - 0.0000000000000000000000000000000000004614 154.0
REGS2_k127_6554124_41 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000004657 143.0
REGS2_k127_6554124_42 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000003697 141.0
REGS2_k127_6554124_43 Transcriptional regulator, MarR family - - - 0.000000000000000000000000000000501 127.0
REGS2_k127_6554124_44 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000001702 133.0
REGS2_k127_6554124_45 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000006884 119.0
REGS2_k127_6554124_46 membrane transporter protein K07090 - - 0.000000000000000000000000000103 126.0
REGS2_k127_6554124_47 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000003887 118.0
REGS2_k127_6554124_48 Cobalt ABC transporter K02008 - - 0.000000000000000000000000001812 129.0
REGS2_k127_6554124_49 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000001023 111.0
REGS2_k127_6554124_5 Aromatic amino acid lyase K01745 - 4.3.1.3 1.698e-215 679.0
REGS2_k127_6554124_50 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000001373 102.0
REGS2_k127_6554124_51 hydrogenase assembly chaperone HypC HupF K04653 - - 0.000000000000000000797 90.0
REGS2_k127_6554124_52 EamA-like transporter family K03298 - - 0.00000000000000000327 99.0
REGS2_k127_6554124_53 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000003053 91.0
REGS2_k127_6554124_54 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000004727 85.0
REGS2_k127_6554124_55 Tautomerase enzyme - - - 0.000008454 53.0
REGS2_k127_6554124_56 Tetratricopeptide repeat - - - 0.00004272 55.0
REGS2_k127_6554124_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 527.0
REGS2_k127_6554124_7 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 503.0
REGS2_k127_6554124_8 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 460.0
REGS2_k127_6554124_9 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 452.0
REGS2_k127_6567059_0 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 414.0
REGS2_k127_6567059_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 337.0
REGS2_k127_6567059_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000101 286.0
REGS2_k127_6567059_3 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000009194 225.0
REGS2_k127_6567059_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000006055 178.0
REGS2_k127_6567059_5 40-residue YVTN family beta-propeller - - - 0.00000000000000000000000000000000000000000000003637 190.0
REGS2_k127_6567059_6 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000001756 154.0
REGS2_k127_6567059_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00006424 50.0
REGS2_k127_6682515_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1246.0
REGS2_k127_6682515_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 349.0
REGS2_k127_6682515_2 - - - - 0.00007291 53.0
REGS2_k127_6718731_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 543.0
REGS2_k127_6718731_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 526.0
REGS2_k127_6718731_10 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000001055 249.0
REGS2_k127_6718731_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000003883 239.0
REGS2_k127_6718731_12 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.00000000000000000000000000000000000000000000000000001072 198.0
REGS2_k127_6718731_13 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000000000000000000000000000006252 192.0
REGS2_k127_6718731_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000382 160.0
REGS2_k127_6718731_15 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000007284 154.0
REGS2_k127_6718731_16 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000008412 139.0
REGS2_k127_6718731_17 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000159 132.0
REGS2_k127_6718731_18 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000285 105.0
REGS2_k127_6718731_19 Helix-turn-helix domain - - - 0.000000000000000000000003278 104.0
REGS2_k127_6718731_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 466.0
REGS2_k127_6718731_20 Zn-dependent protease with chaperone function K03799 - - 0.00001185 57.0
REGS2_k127_6718731_21 Alginate export - - - 0.0000352 53.0
REGS2_k127_6718731_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 463.0
REGS2_k127_6718731_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 427.0
REGS2_k127_6718731_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 355.0
REGS2_k127_6718731_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 355.0
REGS2_k127_6718731_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000005597 266.0
REGS2_k127_6718731_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002181 256.0
REGS2_k127_6718731_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000008845 258.0
REGS2_k127_6751501_0 DNA helicase K03657 - 3.6.4.12 4.351e-237 756.0
REGS2_k127_6751501_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.084e-204 668.0
REGS2_k127_6751501_2 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 554.0
REGS2_k127_6751501_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 473.0
REGS2_k127_6751501_4 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 316.0
REGS2_k127_6751501_5 DHHA2 domain protein K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000001352 181.0
REGS2_k127_6751501_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000001809 176.0
REGS2_k127_6751501_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000001146 150.0
REGS2_k127_6751501_8 Chorismate mutase type II - - - 0.000000000000000000001502 99.0
REGS2_k127_6751501_9 Zinc finger cdgsh-type domain protein - - - 0.000000000000000000003927 96.0
REGS2_k127_6794266_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 449.0
REGS2_k127_6794266_1 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 382.0
REGS2_k127_6794266_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 349.0
REGS2_k127_6794266_3 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 314.0
REGS2_k127_6794266_4 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001439 269.0
REGS2_k127_6794266_5 SMART phosphoesterase PHP domain protein K04477 - - 0.00000000000000000000000000000000000000000000000000000002235 207.0
REGS2_k127_6794266_6 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000003124 141.0
REGS2_k127_6794266_7 PIN domain - - - 0.00000000000001863 74.0
REGS2_k127_6915368_0 ATPases associated with a variety of cellular activities K10441,K10542 - 3.6.3.17 2.813e-205 650.0
REGS2_k127_6915368_1 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 484.0
REGS2_k127_6915368_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 445.0
REGS2_k127_6915368_3 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 364.0
REGS2_k127_6915368_4 EDD domain protein, DegV family - - - 0.0000000000000000000000000000000000000000000001613 180.0
REGS2_k127_6915368_5 Branched-chain amino acid transport system / permease component K10440 - - 0.0002229 48.0
REGS2_k127_6928671_0 Belongs to the SEDS family - - - 1.387e-247 794.0
REGS2_k127_6928671_1 Kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 471.0
REGS2_k127_6928671_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000002219 91.0
REGS2_k127_6928671_11 cell redox homeostasis K02199,K03671 - - 0.000000000000000009312 90.0
REGS2_k127_6928671_12 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000008586 72.0
REGS2_k127_6928671_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 424.0
REGS2_k127_6928671_3 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000462 264.0
REGS2_k127_6928671_4 phosphatase 2C K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000006042 222.0
REGS2_k127_6928671_5 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000002602 217.0
REGS2_k127_6928671_6 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000002055 171.0
REGS2_k127_6928671_7 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000007143 155.0
REGS2_k127_6928671_8 cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000004545 134.0
REGS2_k127_6928671_9 redox-active disulfide protein 2 - - - 0.000000000000000000002853 95.0
REGS2_k127_6961244_0 Radical SAM domain protein - - - 4.693e-208 679.0
REGS2_k127_6961244_1 Cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 485.0
REGS2_k127_6961244_10 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000007883 235.0
REGS2_k127_6961244_11 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000003266 203.0
REGS2_k127_6961244_12 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000003742 196.0
REGS2_k127_6961244_13 protein domain associated with - - - 0.0000000000000000000000000000000000000000000000001319 190.0
REGS2_k127_6961244_14 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000003356 186.0
REGS2_k127_6961244_15 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000142 179.0
REGS2_k127_6961244_16 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000003921 175.0
REGS2_k127_6961244_17 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000002914 148.0
REGS2_k127_6961244_18 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000002141 133.0
REGS2_k127_6961244_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000009603 110.0
REGS2_k127_6961244_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 453.0
REGS2_k127_6961244_20 FMN_bind K03612 - - 0.000000000000000006473 91.0
REGS2_k127_6961244_21 NusG domain II - - - 0.0000000000001919 74.0
REGS2_k127_6961244_22 rod shape-determining protein (MreD) K03571 - - 0.000000000001781 79.0
REGS2_k127_6961244_23 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000001727 67.0
REGS2_k127_6961244_3 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 460.0
REGS2_k127_6961244_4 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 420.0
REGS2_k127_6961244_5 ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 424.0
REGS2_k127_6961244_6 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 411.0
REGS2_k127_6961244_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 325.0
REGS2_k127_6961244_8 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 324.0
REGS2_k127_6961244_9 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000008699 258.0
REGS2_k127_6969846_0 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 533.0
REGS2_k127_6969846_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 411.0
REGS2_k127_6969846_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000001339 160.0
REGS2_k127_6969846_11 Protein of unknown function (DUF2662) - - - 0.000000000000000000000000000000000005415 147.0
REGS2_k127_6969846_12 Transcriptional regulatory protein, C terminal K02483,K07658,K07668 - - 0.00000000000000000000000000000005079 128.0
REGS2_k127_6969846_13 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000005133 116.0
REGS2_k127_6969846_14 FHA domain - - - 0.00000000000000000000009262 107.0
REGS2_k127_6969846_15 phosphatase 2C K20074 - 3.1.3.16 0.000000000000000000005952 98.0
REGS2_k127_6969846_16 Protein of unknown function (DUF4446) - - - 0.00000000000001414 83.0
REGS2_k127_6969846_2 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 306.0
REGS2_k127_6969846_3 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008291 283.0
REGS2_k127_6969846_4 PFAM HhH-GPD family protein K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001058 278.0
REGS2_k127_6969846_5 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001143 274.0
REGS2_k127_6969846_6 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002242 270.0
REGS2_k127_6969846_7 Kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008081 267.0
REGS2_k127_6969846_8 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000001568 207.0
REGS2_k127_6969846_9 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000003156 194.0
REGS2_k127_7093134_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.122e-232 735.0
REGS2_k127_7093134_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 6.683e-221 695.0
REGS2_k127_7093134_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000001363 260.0
REGS2_k127_7093134_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000838 187.0
REGS2_k127_7093134_4 ATP synthase subunit C K02124 - - 0.00000000000000000000000000008245 126.0
REGS2_k127_7093134_5 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000000000000001445 112.0
REGS2_k127_7093134_6 General secretory system II protein E domain protein - - - 0.00000000000000000000002706 109.0
REGS2_k127_7093134_7 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000001641 83.0
REGS2_k127_7093134_8 ATP synthase, subunit F K02122 - - 0.0000000006546 70.0
REGS2_k127_7093608_0 Anion-transporting ATPase K01551 - 3.6.3.16 1.91e-209 670.0
REGS2_k127_7093608_1 Magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 503.0
REGS2_k127_7093608_10 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000003367 241.0
REGS2_k127_7093608_11 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000006375 222.0
REGS2_k127_7093608_12 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000004971 217.0
REGS2_k127_7093608_13 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000001163 169.0
REGS2_k127_7093608_14 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 0.0000000000000000000000000000000000000000005053 170.0
REGS2_k127_7093608_15 Arsenical resistance operon trans-acting repressor ArsD - - - 0.00000000000000000000000000000009998 126.0
REGS2_k127_7093608_16 Domain of unknown function DUF302 - - - 0.000000000000000000000000000002577 132.0
REGS2_k127_7093608_17 - - - - 0.00000000000000000000000000003869 128.0
REGS2_k127_7093608_18 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000001275 128.0
REGS2_k127_7093608_19 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000000000002154 99.0
REGS2_k127_7093608_2 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 487.0
REGS2_k127_7093608_20 Redoxin - - - 0.000000000006677 70.0
REGS2_k127_7093608_21 Acetyltransferase (GNAT) domain - - - 0.000000000007767 74.0
REGS2_k127_7093608_22 - - - - 0.0000000003493 72.0
REGS2_k127_7093608_23 Protein of unknown function (DUF2892) - - - 0.00005057 53.0
REGS2_k127_7093608_24 Helix-turn-helix domain - - - 0.00009115 53.0
REGS2_k127_7093608_3 TIGRFAM Arsenical-resistance protein K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 460.0
REGS2_k127_7093608_4 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 444.0
REGS2_k127_7093608_5 E1-E2 ATPase K01533,K12956 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 428.0
REGS2_k127_7093608_6 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 390.0
REGS2_k127_7093608_7 ABC transporter, ATP-binding protein K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000214 275.0
REGS2_k127_7093608_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000162 274.0
REGS2_k127_7093608_9 ABC transporter, phosphonate, periplasmic substrate-binding protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000117 259.0
REGS2_k127_7122991_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 606.0
REGS2_k127_7122991_1 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 582.0
REGS2_k127_7122991_10 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000001387 125.0
REGS2_k127_7122991_11 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000007636 90.0
REGS2_k127_7122991_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00001048 57.0
REGS2_k127_7122991_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 504.0
REGS2_k127_7122991_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000006113 250.0
REGS2_k127_7122991_4 Cytochrome b/b6/petB K03620 - - 0.000000000000000000000000000000000000000000000000000001013 199.0
REGS2_k127_7122991_5 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000002285 193.0
REGS2_k127_7122991_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000001921 171.0
REGS2_k127_7122991_7 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000002772 171.0
REGS2_k127_7122991_8 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000002255 132.0
REGS2_k127_7122991_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000008353 136.0
REGS2_k127_7124909_0 PFAM cation transporter K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 548.0
REGS2_k127_7124909_1 PFAM FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 521.0
REGS2_k127_7124909_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000002883 139.0
REGS2_k127_7124909_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000008819 138.0
REGS2_k127_7124909_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000005554 122.0
REGS2_k127_7124909_13 - - - - 0.0000000000000000000000006867 115.0
REGS2_k127_7124909_14 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000177 89.0
REGS2_k127_7124909_15 Bacterial regulatory proteins, tetR family - - - 0.0000000000657 75.0
REGS2_k127_7124909_16 - - - - 0.00000003982 64.0
REGS2_k127_7124909_18 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00005363 55.0
REGS2_k127_7124909_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 436.0
REGS2_k127_7124909_3 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 410.0
REGS2_k127_7124909_4 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 403.0
REGS2_k127_7124909_5 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 389.0
REGS2_k127_7124909_6 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 293.0
REGS2_k127_7124909_7 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000004196 233.0
REGS2_k127_7124909_8 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000003716 192.0
REGS2_k127_7124909_9 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000157 161.0
REGS2_k127_7141369_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 1.234e-214 682.0
REGS2_k127_7141369_1 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 6.919e-200 634.0
REGS2_k127_7141369_10 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000001164 272.0
REGS2_k127_7141369_11 COGs COG0647 sugar phosphatase of the HAD superfamily K01101 - 3.1.3.41 0.000000000000000000000000000000000004522 149.0
REGS2_k127_7141369_12 Glycosyltransferase family 87 - - - 0.00000000000000000000000008165 124.0
REGS2_k127_7141369_13 GtrA-like protein - - - 0.0000003927 62.0
REGS2_k127_7141369_2 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 593.0
REGS2_k127_7141369_3 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 572.0
REGS2_k127_7141369_4 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 410.0
REGS2_k127_7141369_5 ADP-glyceromanno-heptose 6-epimerase activity K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 411.0
REGS2_k127_7141369_6 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 394.0
REGS2_k127_7141369_7 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 320.0
REGS2_k127_7141369_8 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 304.0
REGS2_k127_7141369_9 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006331 282.0
REGS2_k127_7449448_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 607.0
REGS2_k127_7449448_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 391.0
REGS2_k127_7449448_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000006901 128.0
REGS2_k127_7458181_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.068e-316 983.0
REGS2_k127_7458181_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.541e-297 921.0
REGS2_k127_7458181_2 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000007607 217.0
REGS2_k127_7458181_3 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000009762 171.0
REGS2_k127_7458181_4 SLBB domain K02237 - - 0.0000000000000000000000000000000007355 139.0
REGS2_k127_7458181_5 heat shock protein binding - - - 0.0000000000000000000000000548 121.0
REGS2_k127_7458181_6 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000008516 103.0
REGS2_k127_7516141_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 586.0
REGS2_k127_7516141_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 556.0
REGS2_k127_7516141_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 512.0
REGS2_k127_7516141_3 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 461.0
REGS2_k127_7516141_4 penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 449.0
REGS2_k127_7516141_5 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 449.0
REGS2_k127_7516141_6 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 344.0
REGS2_k127_7516141_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000009051 187.0
REGS2_k127_7516141_8 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000004979 177.0
REGS2_k127_7516141_9 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000000000003764 167.0
REGS2_k127_7807120_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 430.0
REGS2_k127_7807120_1 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 360.0
REGS2_k127_7807120_2 Uncharacterised protein family (UPF0014) K02069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006228 272.0
REGS2_k127_7807120_3 ATPases associated with a variety of cellular activities K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002875 271.0
REGS2_k127_7807120_4 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000001061 222.0
REGS2_k127_7807120_5 ATPases associated with a variety of cellular activities K02068 - - 0.000000000000000000000000000000000000000000004678 171.0
REGS2_k127_7807120_6 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000002179 119.0
REGS2_k127_7807120_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000001687 85.0
REGS2_k127_7807120_8 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00003703 55.0
REGS2_k127_7815305_0 Glutamate synthase (NADPH) GltB1 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 468.0
REGS2_k127_7815305_1 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 415.0
REGS2_k127_7815305_10 - - - - 0.0003691 51.0
REGS2_k127_7815305_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 409.0
REGS2_k127_7815305_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 355.0
REGS2_k127_7815305_4 Signal transduction histidine kinase K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000002787 259.0
REGS2_k127_7815305_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004268 249.0
REGS2_k127_7815305_6 Response regulator receiver K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000003091 227.0
REGS2_k127_7815305_7 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000005002 154.0
REGS2_k127_7815305_8 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000007049 132.0
REGS2_k127_7815305_9 Nacht domain - - - 0.000000004719 66.0
REGS2_k127_7859113_0 Putative glucoamylase K13688 - - 0.0 2441.0
REGS2_k127_7859113_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1122.0
REGS2_k127_7859113_10 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000003212 221.0
REGS2_k127_7859113_11 IA, variant 3 K06019 - 3.6.1.1 0.000000000000000000000000000000000000000000000000003479 189.0
REGS2_k127_7859113_12 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000007099 156.0
REGS2_k127_7859113_13 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000009149 139.0
REGS2_k127_7859113_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000004958 94.0
REGS2_k127_7859113_15 COG0607 Rhodanese-related sulfurtransferase K03972 - - 0.000000000000005844 85.0
REGS2_k127_7859113_16 - - - - 0.000000000001661 75.0
REGS2_k127_7859113_17 - - - - 0.00000002078 62.0
REGS2_k127_7859113_18 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K06196 - - 0.0000001012 56.0
REGS2_k127_7859113_19 - - - - 0.00001435 50.0
REGS2_k127_7859113_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.634e-263 825.0
REGS2_k127_7859113_3 Belongs to the 5'-nucleotidase family - - - 3.65e-206 653.0
REGS2_k127_7859113_4 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 574.0
REGS2_k127_7859113_5 Bacterial dnaA protein helix-turn-helix domain K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 477.0
REGS2_k127_7859113_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 344.0
REGS2_k127_7859113_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 307.0
REGS2_k127_7859113_8 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 295.0
REGS2_k127_7859113_9 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001622 281.0
REGS2_k127_8039673_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 543.0
REGS2_k127_8039673_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 489.0
REGS2_k127_8039673_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 407.0
REGS2_k127_8039673_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 325.0
REGS2_k127_8039673_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000296 286.0
REGS2_k127_8039673_5 Cellulose biosynthesis protein BcsQ K02282 - - 0.00000000000000000000001059 106.0
REGS2_k127_8039673_6 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000006278 95.0
REGS2_k127_8106945_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.353e-247 785.0
REGS2_k127_8106945_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 7.205e-231 729.0
REGS2_k127_8106945_10 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000005285 92.0
REGS2_k127_8106945_11 - - - - 0.0000000000000004062 82.0
REGS2_k127_8106945_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000003842 84.0
REGS2_k127_8106945_2 glycolate transport K14393 - - 2.31e-205 658.0
REGS2_k127_8106945_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 447.0
REGS2_k127_8106945_4 riboflavin biosynthesis protein K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000001654 234.0
REGS2_k127_8106945_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000006753 233.0
REGS2_k127_8106945_6 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000006723 200.0
REGS2_k127_8106945_7 - - - - 0.0000000000000000000000000000000000002097 147.0
REGS2_k127_8106945_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000001153 143.0
REGS2_k127_8106945_9 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.000000000000000000004757 95.0
REGS2_k127_817084_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 2.549e-231 747.0
REGS2_k127_817084_1 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 546.0
REGS2_k127_817084_10 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000005726 243.0
REGS2_k127_817084_11 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000004415 222.0
REGS2_k127_817084_12 - - - - 0.00000000000000000000000000000000000000000000000000000000004674 214.0
REGS2_k127_817084_13 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000002542 211.0
REGS2_k127_817084_14 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000009348 212.0
REGS2_k127_817084_15 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000004309 222.0
REGS2_k127_817084_16 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000006723 213.0
REGS2_k127_817084_17 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000002295 173.0
REGS2_k127_817084_18 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000004993 178.0
REGS2_k127_817084_19 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.0000000000000000000000000000000000000009207 156.0
REGS2_k127_817084_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 532.0
REGS2_k127_817084_20 Peptidyl-prolyl cis-trans isomerase K01802,K03774,K03775 - 5.2.1.8 0.000000000000000000000000000000000000006242 155.0
REGS2_k127_817084_21 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000007628 162.0
REGS2_k127_817084_22 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000595 153.0
REGS2_k127_817084_23 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000002085 157.0
REGS2_k127_817084_24 Major facilitator Superfamily K03291 - - 0.0000000000000000000000000000000001018 149.0
REGS2_k127_817084_25 GHKL domain K07315 - 3.1.3.3 0.000000000000000000000000000000000784 141.0
REGS2_k127_817084_26 methyltransferase - - - 0.00000000000000000000000000000001778 145.0
REGS2_k127_817084_27 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000485 130.0
REGS2_k127_817084_28 Maf-like protein K06287 - - 0.000000000000000000000000006341 127.0
REGS2_k127_817084_29 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000002334 116.0
REGS2_k127_817084_3 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 375.0
REGS2_k127_817084_30 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000001603 97.0
REGS2_k127_817084_31 PspC domain K03973 - - 0.000000000000000151 82.0
REGS2_k127_817084_32 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000008101 91.0
REGS2_k127_817084_33 lyase activity - - - 0.000000000000003816 90.0
REGS2_k127_817084_34 YtxH-like protein - - - 0.0000000004583 68.0
REGS2_k127_817084_35 - - - - 0.000000001796 69.0
REGS2_k127_817084_36 - - - - 0.000000003743 64.0
REGS2_k127_817084_37 PFAM PspC domain protein K03973 - - 0.000000004833 64.0
REGS2_k127_817084_38 PFAM PRC-barrel domain - - - 0.00000001517 65.0
REGS2_k127_817084_39 PspC domain - - - 0.00001215 53.0
REGS2_k127_817084_4 pfam abc K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 355.0
REGS2_k127_817084_40 Transcriptional regulator - - - 0.0002481 49.0
REGS2_k127_817084_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 312.0
REGS2_k127_817084_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004821 278.0
REGS2_k127_817084_7 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001694 254.0
REGS2_k127_817084_8 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000005635 232.0
REGS2_k127_817084_9 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000006899 228.0
REGS2_k127_8212732_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.475e-253 799.0
REGS2_k127_8212732_1 DNA ligase K01971 - 6.5.1.1 8.349e-227 734.0
REGS2_k127_8212732_10 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000005297 237.0
REGS2_k127_8212732_11 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000004862 236.0
REGS2_k127_8212732_12 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000001071 196.0
REGS2_k127_8212732_13 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000007228 198.0
REGS2_k127_8212732_14 PFAM isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000001594 170.0
REGS2_k127_8212732_15 COG2199 FOG GGDEF domain - - - 0.00000000000000000000000000000000002697 150.0
REGS2_k127_8212732_16 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000004648 108.0
REGS2_k127_8212732_17 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000009015 100.0
REGS2_k127_8212732_18 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000228 85.0
REGS2_k127_8212732_19 cell wall binding repeat - - - 0.000000000000002577 88.0
REGS2_k127_8212732_2 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.77e-205 656.0
REGS2_k127_8212732_20 - - - - 0.000000000004168 74.0
REGS2_k127_8212732_21 metal-dependent membrane protease K07052 - - 0.000000001516 70.0
REGS2_k127_8212732_22 protein histidine kinase activity K07814,K11527 - 2.7.13.3 0.000000002054 70.0
REGS2_k127_8212732_23 COG0784 FOG CheY-like receiver - - - 0.000000004329 68.0
REGS2_k127_8212732_24 Integral membrane protein - - - 0.000000402 62.0
REGS2_k127_8212732_25 Nitrite and sulphite reductase 4Fe-4S domain K21816 - 1.8.98.3 0.0000004347 62.0
REGS2_k127_8212732_26 membrane K21471 - - 0.00001841 57.0
REGS2_k127_8212732_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 581.0
REGS2_k127_8212732_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 554.0
REGS2_k127_8212732_5 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 527.0
REGS2_k127_8212732_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 506.0
REGS2_k127_8212732_7 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 352.0
REGS2_k127_8212732_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 339.0
REGS2_k127_8212732_9 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002304 253.0
REGS2_k127_8218754_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1058.0
REGS2_k127_8218754_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 570.0
REGS2_k127_8218754_10 Double zinc ribbon - - - 0.00000000000000000000000000000000000002728 149.0
REGS2_k127_8218754_12 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00004278 53.0
REGS2_k127_8218754_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 338.0
REGS2_k127_8218754_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 302.0
REGS2_k127_8218754_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002959 274.0
REGS2_k127_8218754_5 Mur ligase, middle domain protein K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000001122 262.0
REGS2_k127_8218754_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000003057 265.0
REGS2_k127_8218754_7 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000001857 207.0
REGS2_k127_8218754_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000002362 199.0
REGS2_k127_8218754_9 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.000000000000000000000000000000000000001488 166.0
REGS2_k127_8301334_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.674e-196 634.0
REGS2_k127_8301334_1 Alpha-amylase domain K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 485.0
REGS2_k127_8301334_2 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005887 256.0
REGS2_k127_8301334_3 Voltage-dependent anion channel K11041 - - 0.00000000000000000000000000000000000000000000000000000000000000000001233 243.0
REGS2_k127_8301334_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01563,K04075,K11991 - 3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000001015 213.0
REGS2_k127_8301334_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000006524 206.0
REGS2_k127_8301334_6 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000003338 188.0
REGS2_k127_8301334_7 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000003322 136.0
REGS2_k127_8301334_8 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000001865 98.0
REGS2_k127_8301334_9 alcohol dehydrogenase K00001 - 1.1.1.1 0.000000002674 60.0
REGS2_k127_8341268_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.617e-264 834.0
REGS2_k127_8341268_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 300.0
REGS2_k127_8341268_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 288.0
REGS2_k127_8341268_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000002154 98.0
REGS2_k127_8341268_5 - - - - 0.0000002903 60.0
REGS2_k127_8366888_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 9.441e-215 688.0
REGS2_k127_8366888_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 515.0
REGS2_k127_8366888_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 480.0
REGS2_k127_8366888_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 400.0
REGS2_k127_8366888_4 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 320.0
REGS2_k127_8366888_5 PIN domain - - - 0.0000000000001128 76.0
REGS2_k127_8366888_6 Exopolysaccharide production protein K16568 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000008604 57.0
REGS2_k127_8465050_0 DNA topoisomerase K03168 - 5.99.1.2 3.14e-264 835.0
REGS2_k127_8465050_1 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 373.0
REGS2_k127_8465050_10 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000007299 172.0
REGS2_k127_8465050_11 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000008514 140.0
REGS2_k127_8465050_12 - - - - 0.0000004203 62.0
REGS2_k127_8465050_2 Belongs to the LDH MDH superfamily K00016,K00024 - 1.1.1.27,1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 353.0
REGS2_k127_8465050_3 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 327.0
REGS2_k127_8465050_4 PSP1 C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 301.0
REGS2_k127_8465050_5 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 301.0
REGS2_k127_8465050_6 PDZ DHR GLGF domain protein K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002317 262.0
REGS2_k127_8465050_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002792 259.0
REGS2_k127_8465050_8 Fumarase C-terminus K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000017 204.0
REGS2_k127_8465050_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000005914 209.0
REGS2_k127_8513253_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 512.0
REGS2_k127_8513253_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 391.0
REGS2_k127_8513253_10 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.00000000000000000000594 95.0
REGS2_k127_8513253_11 Cupredoxin-like domain - - - 0.000000000000000562 84.0
REGS2_k127_8513253_12 bacterioferritin comigratory protein K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.0000001373 56.0
REGS2_k127_8513253_13 RNA-binding protein containing a PIN domain K06962 - - 0.0000009586 58.0
REGS2_k127_8513253_14 Protein of unknown function (DUF1003) - - - 0.00005936 47.0
REGS2_k127_8513253_15 Protein of unknown function (DUF554) K07150 - - 0.0004353 44.0
REGS2_k127_8513253_2 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 350.0
REGS2_k127_8513253_3 DEAD DEAH box helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 353.0
REGS2_k127_8513253_4 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 311.0
REGS2_k127_8513253_5 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 307.0
REGS2_k127_8513253_6 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 302.0
REGS2_k127_8513253_7 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003215 250.0
REGS2_k127_8513253_8 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000003497 160.0
REGS2_k127_8513253_9 heat shock protein binding - - - 0.000000000000000000000000000000000009727 152.0
REGS2_k127_8529421_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 599.0
REGS2_k127_8529421_1 PFAM Haemolysin-type calcium-binding repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004281 298.0
REGS2_k127_8529421_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000009463 247.0
REGS2_k127_8529421_3 regulation of early endosome to recycling endosome transport - - - 0.0000000000000000000005639 113.0
REGS2_k127_8529421_4 cellulase activity - - - 0.0000000009134 73.0