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Overview

ID MAG03368
Name SHD1_bin.6
Sample SMP0082
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family Gemmatimonadaceae
Genus FEN-1250
Species FEN-1250 sp035310785
Assembly information
Completeness (%) 84.57
Contamination (%) 4.48
GC content (%) 66.0
N50 (bp) 7,080
Genome size (bp) 3,267,242

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3031

Gene name Description KEGG GOs EC E-value Score Sequence
SHD1_k127_1005253_0 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 364.0
SHD1_k127_1005253_1 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 313.0
SHD1_k127_1005253_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000001771 170.0
SHD1_k127_1005253_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000006789 87.0
SHD1_k127_1005253_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000001712 53.0
SHD1_k127_1008506_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 1.301e-209 655.0
SHD1_k127_1008506_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 346.0
SHD1_k127_1008506_2 SprT-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006629 243.0
SHD1_k127_1008506_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000002516 173.0
SHD1_k127_1008890_0 Catalase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006731 262.0
SHD1_k127_1008890_1 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008361 252.0
SHD1_k127_1014779_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 1.06e-310 968.0
SHD1_k127_1014779_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 471.0
SHD1_k127_1014779_2 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 395.0
SHD1_k127_1014779_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 334.0
SHD1_k127_1014779_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 336.0
SHD1_k127_1014779_5 deaminated base DNA N-glycosylase activity K03648,K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000001335 228.0
SHD1_k127_1014779_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000005989 216.0
SHD1_k127_1014779_7 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000006712 177.0
SHD1_k127_1025427_0 - K01286 - 3.4.16.4 0.000000000000000000000000000000000000000251 162.0
SHD1_k127_1025427_1 Penicillinase repressor - - - 0.00000000000000000000000000000000000001638 149.0
SHD1_k127_1025427_2 ATPases of PP-loop superfamily - - - 0.0000000000000000000006199 99.0
SHD1_k127_1027697_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1258.0
SHD1_k127_1027697_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.787e-214 673.0
SHD1_k127_1027697_2 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 451.0
SHD1_k127_1027697_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 332.0
SHD1_k127_1027697_4 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.000000000000000000000000000000000000000000000000000000000003675 218.0
SHD1_k127_1027697_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000003401 158.0
SHD1_k127_1027697_6 Ribosomal protein S16 K02959 - - 0.0000000000000000000000000000000005513 134.0
SHD1_k127_1029582_0 glyoxalase III activity K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000004519 209.0
SHD1_k127_1029582_1 DinB family - - - 0.0000000000000000000000000000000000000002019 157.0
SHD1_k127_1029582_2 COG4635 Flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000000000000000000166 155.0
SHD1_k127_1029582_3 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000002419 133.0
SHD1_k127_1029582_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000003253 121.0
SHD1_k127_1029582_5 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000001825 120.0
SHD1_k127_1029582_6 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000008728 117.0
SHD1_k127_1036041_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.206e-259 810.0
SHD1_k127_1036041_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 5.425e-204 648.0
SHD1_k127_1036041_2 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000002564 260.0
SHD1_k127_1036041_3 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000000005155 166.0
SHD1_k127_1036041_4 - - - - 0.00000000000000000000000001321 111.0
SHD1_k127_1036041_5 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000006646 58.0
SHD1_k127_1051402_0 cellulose binding - - - 1.772e-224 699.0
SHD1_k127_1051402_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 508.0
SHD1_k127_1051402_2 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001393 261.0
SHD1_k127_1051402_3 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001804 255.0
SHD1_k127_1051402_4 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000003205 142.0
SHD1_k127_1059488_0 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 398.0
SHD1_k127_1059488_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 318.0
SHD1_k127_1059488_2 Has an organic peroxide-dependent peroxidase activity K03781 - 1.11.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009345 286.0
SHD1_k127_1059488_3 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000007088 79.0
SHD1_k127_1064929_0 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 486.0
SHD1_k127_1064929_1 Diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 316.0
SHD1_k127_1064929_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000001571 234.0
SHD1_k127_106773_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 573.0
SHD1_k127_106773_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000007311 236.0
SHD1_k127_106773_2 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000001376 196.0
SHD1_k127_106773_3 Ribosomal L28 family K02902 - - 0.0000000000000000000000000009203 113.0
SHD1_k127_1075093_0 transmembrane transporter activity K03296 - - 0.0 1242.0
SHD1_k127_1075093_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 478.0
SHD1_k127_1075093_2 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 347.0
SHD1_k127_1075093_3 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
SHD1_k127_1075093_4 efflux transmembrane transporter activity K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 295.0
SHD1_k127_1075093_5 Transcriptional regulatory protein, C terminal K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000001084 244.0
SHD1_k127_1075093_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000001794 181.0
SHD1_k127_1075093_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000004701 168.0
SHD1_k127_1075093_8 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000001415 146.0
SHD1_k127_1086216_0 4Fe-4S binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 563.0
SHD1_k127_1086216_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 535.0
SHD1_k127_1086216_2 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 338.0
SHD1_k127_1086216_3 PFAM NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000007271 162.0
SHD1_k127_1086216_4 COGs COG4293 conserved - - - 0.0000000000000000000000000000000005267 138.0
SHD1_k127_1086216_5 FAD binding domain K11472 - - 0.0000000000000000005266 93.0
SHD1_k127_1086216_6 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01091,K01838 - 3.1.3.18,5.4.2.6 0.0000000000132 73.0
SHD1_k127_1086216_7 cellular component assembly - - - 0.0000002031 64.0
SHD1_k127_1088527_0 Ftsk_gamma K03466 - - 8.063e-255 813.0
SHD1_k127_1088527_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 424.0
SHD1_k127_1088527_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 364.0
SHD1_k127_1088527_3 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 311.0
SHD1_k127_1089117_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000002588 166.0
SHD1_k127_1089117_1 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000003031 142.0
SHD1_k127_1089117_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000001573 76.0
SHD1_k127_1097548_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 1.003e-257 800.0
SHD1_k127_1097548_1 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 530.0
SHD1_k127_1097548_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 501.0
SHD1_k127_1097548_3 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 296.0
SHD1_k127_1108179_0 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 522.0
SHD1_k127_1108179_1 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000572 186.0
SHD1_k127_1110425_0 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 331.0
SHD1_k127_1110425_1 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001471 276.0
SHD1_k127_1110425_2 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000004928 234.0
SHD1_k127_1110425_3 - - - - 0.0000000000000000000000000000000000000000000000000000001502 207.0
SHD1_k127_1113679_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 533.0
SHD1_k127_1113679_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000935 286.0
SHD1_k127_1113679_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007931 263.0
SHD1_k127_1113679_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000084 226.0
SHD1_k127_1113679_4 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000001761 150.0
SHD1_k127_1113679_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000009428 94.0
SHD1_k127_1113679_6 Methyltransferase domain - - - 0.0000000002604 71.0
SHD1_k127_1113679_8 alginic acid biosynthetic process K10297 - - 0.0005538 45.0
SHD1_k127_1114502_0 Glycosyl hydrolases family 18 - - - 0.0 1112.0
SHD1_k127_1114502_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000002011 234.0
SHD1_k127_1117240_0 DNA polymerase alpha chain like domain K02347 - - 6.158e-216 684.0
SHD1_k127_1117240_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 442.0
SHD1_k127_1117240_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 359.0
SHD1_k127_1117240_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 347.0
SHD1_k127_1117240_4 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
SHD1_k127_1117240_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002321 278.0
SHD1_k127_1117240_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000441 247.0
SHD1_k127_1117240_7 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591 - - 0.0000000000000000000000000000000000000000000000000000000000000000003697 242.0
SHD1_k127_1117240_8 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000001067 182.0
SHD1_k127_1117240_9 - - - - 0.00000000000000000000000000000000005736 139.0
SHD1_k127_1118647_0 DNA restriction-modification system - - - 3.475e-291 927.0
SHD1_k127_1118647_1 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006155 298.0
SHD1_k127_1118647_2 PFAM Glycosyl transferase family 2 K00721,K09809 - 2.4.1.83,2.7.8.12 0.000000001592 66.0
SHD1_k127_1126256_0 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 467.0
SHD1_k127_1126256_1 Rhodanese Homology Domain K01069,K03797 - 3.1.2.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009428 267.0
SHD1_k127_1126256_2 Protein conserved in bacteria - - - 0.00000000000000000000005338 105.0
SHD1_k127_1140346_0 Sortilin, neurotensin receptor 3, - - - 1.863e-314 981.0
SHD1_k127_1143050_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 2.115e-279 885.0
SHD1_k127_1144434_0 Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 592.0
SHD1_k127_1144434_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 328.0
SHD1_k127_1144434_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001566 272.0
SHD1_k127_1144434_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000002743 235.0
SHD1_k127_1144434_4 DnaB-like helicase C terminal domain K02314 - 3.6.4.12 0.000000000000000000000000000002932 125.0
SHD1_k127_1144434_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000003745 115.0
SHD1_k127_115489_0 Belongs to the thiolase family K07508,K17972 GO:0001666,GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006915,GO:0006950,GO:0006996,GO:0007005,GO:0007006,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008219,GO:0008610,GO:0008637,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009628,GO:0009966,GO:0009968,GO:0009987,GO:0010639,GO:0010646,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0012501,GO:0016042,GO:0016043,GO:0016054,GO:0016125,GO:0016126,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0023051,GO:0023057,GO:0030258,GO:0031974,GO:0032787,GO:0032879,GO:0033043,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0035795,GO:0036293,GO:0036294,GO:0042221,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046165,GO:0046395,GO:0046483,GO:0046902,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051179,GO:0051186,GO:0051234,GO:0051716,GO:0055086,GO:0055114,GO:0060548,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0072329,GO:0072521,GO:0090559,GO:1901028,GO:1901029,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902108,GO:1902109,GO:1902652,GO:1902653,GO:1905709,GO:2001233,GO:2001234 2.3.1.16,2.3.1.254 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 439.0
SHD1_k127_115489_1 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 377.0
SHD1_k127_115489_2 - - - - 0.000000000000000000000000000000000000000000000000000000007739 211.0
SHD1_k127_115489_3 - - - - 0.000000000000000000000000000000000001005 147.0
SHD1_k127_115489_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000002449 137.0
SHD1_k127_1157184_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000258 142.0
SHD1_k127_1171440_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.063e-238 761.0
SHD1_k127_1171440_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 376.0
SHD1_k127_1171440_2 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 312.0
SHD1_k127_1171440_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000002205 210.0
SHD1_k127_1178272_0 ABC transporter K06158 - - 6.611e-252 794.0
SHD1_k127_1178272_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 2.001e-226 729.0
SHD1_k127_1178272_10 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000003544 204.0
SHD1_k127_1178272_11 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.00000000000000000000000000000000000000000000002149 179.0
SHD1_k127_1178272_12 ArsC family - - - 0.0000000000000000000000000000000000000000003293 164.0
SHD1_k127_1178272_13 protein tyrosine kinase activity K16692 - - 0.00000000000000000000001646 110.0
SHD1_k127_1178272_14 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000002753 61.0
SHD1_k127_1178272_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 439.0
SHD1_k127_1178272_3 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 402.0
SHD1_k127_1178272_4 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 387.0
SHD1_k127_1178272_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 344.0
SHD1_k127_1178272_6 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 338.0
SHD1_k127_1178272_7 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 304.0
SHD1_k127_1178272_8 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
SHD1_k127_1178272_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001106 252.0
SHD1_k127_1181744_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 521.0
SHD1_k127_1181744_1 FCD - - - 0.00000000000000000000000000004949 130.0
SHD1_k127_1181744_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000078 99.0
SHD1_k127_1185709_0 radical SAM domain protein - - - 1.306e-196 627.0
SHD1_k127_1185709_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 559.0
SHD1_k127_1202302_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 7.173e-202 651.0
SHD1_k127_1202302_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 494.0
SHD1_k127_1202302_2 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 481.0
SHD1_k127_1202302_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 311.0
SHD1_k127_1202302_4 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000009027 151.0
SHD1_k127_1202302_5 - - - - 0.0000000000000000000000000000000001131 139.0
SHD1_k127_1202302_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000002911 92.0
SHD1_k127_1202302_7 chemotaxis protein K03407 - 2.7.13.3 0.0003521 45.0
SHD1_k127_1209142_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1540.0
SHD1_k127_1209142_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 371.0
SHD1_k127_1209142_2 Serine dehydratase beta chain K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 342.0
SHD1_k127_1209142_3 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000001258 238.0
SHD1_k127_1209142_4 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000001438 155.0
SHD1_k127_1209142_5 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000005338 145.0
SHD1_k127_1209861_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 6.642e-274 863.0
SHD1_k127_1209861_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000001891 127.0
SHD1_k127_1209861_2 - K04096 - - 0.0000000000000000000000000000001005 128.0
SHD1_k127_1217857_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1363.0
SHD1_k127_1217857_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 8.783e-260 822.0
SHD1_k127_1217857_2 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 290.0
SHD1_k127_1217857_3 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005315 285.0
SHD1_k127_1217857_4 YGGT family K02221 - - 0.0000000000000000000000000000000000000000000008395 173.0
SHD1_k127_1217857_5 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000005677 162.0
SHD1_k127_1217857_6 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000001304 127.0
SHD1_k127_1217857_7 PFAM VanZ like family - - - 0.0000000007454 71.0
SHD1_k127_123772_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.608e-241 753.0
SHD1_k127_123772_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 429.0
SHD1_k127_1250200_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000001114 244.0
SHD1_k127_1250200_1 Formate/nitrite transporter K21990,K21993 - - 0.0000000000000000000000000000000000000000000000000014 193.0
SHD1_k127_1250200_2 NlpC/P60 family - - - 0.0000000000000000000000000000000000000897 151.0
SHD1_k127_1250200_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.0000000000000000000000000003104 116.0
SHD1_k127_1250200_4 prohibitin homologues - - - 0.000000000000004717 78.0
SHD1_k127_1250200_5 - - - - 0.0000000000006892 71.0
SHD1_k127_1279526_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 612.0
SHD1_k127_1280853_0 - - - - 0.0000000000000000000000003718 108.0
SHD1_k127_1280853_1 Sortase family K07284 - 3.4.22.70 0.000000000000000001067 93.0
SHD1_k127_129245_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 539.0
SHD1_k127_129245_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000007674 192.0
SHD1_k127_129245_2 - - - - 0.00000000000000000000000000000005035 127.0
SHD1_k127_1293343_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 602.0
SHD1_k127_1293343_1 E1-E2 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 524.0
SHD1_k127_1293343_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 302.0
SHD1_k127_1293343_3 helix_turn_helix, Lux Regulon K02282,K07696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000198 250.0
SHD1_k127_1293343_4 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000001169 215.0
SHD1_k127_1293343_5 - - - - 0.0000000000000000000000000000000005227 137.0
SHD1_k127_1298729_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 370.0
SHD1_k127_1298729_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 346.0
SHD1_k127_1298729_2 Protein of unknown function DUF116 - - - 0.000000000000000000000000000000001062 149.0
SHD1_k127_1298729_3 - - - - 0.0000000000000000000000005566 116.0
SHD1_k127_1302379_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K00392 - 1.7.7.1,1.8.7.1 1.954e-279 870.0
SHD1_k127_1302379_1 acetyltransferase K22441 - 2.3.1.57 0.0000000000000000000000000000000000000003758 165.0
SHD1_k127_1302379_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000003345 127.0
SHD1_k127_1304480_0 chaperone-mediated protein folding - - - 1.591e-196 625.0
SHD1_k127_1304480_1 - - - - 0.0000000000000000000000000000000000000001944 157.0
SHD1_k127_1304480_2 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000006336 86.0
SHD1_k127_1321405_0 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 500.0
SHD1_k127_1321405_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000001075 213.0
SHD1_k127_1321405_3 DinB family - - - 0.0000000000000000000000000000000000000088 152.0
SHD1_k127_1321405_4 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000007917 149.0
SHD1_k127_1321405_6 Anti-sigma-K factor rskA - - - 0.0000000000004216 79.0
SHD1_k127_1338280_0 synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 419.0
SHD1_k127_1338280_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 347.0
SHD1_k127_1338280_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001116 251.0
SHD1_k127_1338280_3 Peptidase dimerisation domain - - - 0.00000000000000001334 87.0
SHD1_k127_1342986_0 response to antibiotic K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 591.0
SHD1_k127_1342986_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000001936 239.0
SHD1_k127_1342986_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000012 107.0
SHD1_k127_1355003_0 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000005983 213.0
SHD1_k127_1355003_1 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000001401 203.0
SHD1_k127_1355003_2 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000009653 156.0
SHD1_k127_1356455_0 MMPL family K03296 - - 0.0 1154.0
SHD1_k127_1356455_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 462.0
SHD1_k127_1356455_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000004984 117.0
SHD1_k127_1356455_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 346.0
SHD1_k127_1356455_3 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 290.0
SHD1_k127_1356455_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001452 285.0
SHD1_k127_1356455_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007486 267.0
SHD1_k127_1356455_6 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003435 263.0
SHD1_k127_1356455_7 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001694 242.0
SHD1_k127_1356455_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000001393 224.0
SHD1_k127_1356455_9 AntiSigma factor - - - 0.00000000000000000000000000000000000000008126 164.0
SHD1_k127_1382637_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 542.0
SHD1_k127_1382637_1 transporter K07238,K11021,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000001324 246.0
SHD1_k127_1382637_2 - - - - 0.0000000000000000000000000000000000000000000000000000000463 200.0
SHD1_k127_1382637_3 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000005745 66.0
SHD1_k127_1382923_0 Glycosyl hydrolase family 1 K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 396.0
SHD1_k127_1382923_1 helix_turn_helix, Lux Regulon - - - 0.00003401 48.0
SHD1_k127_1401037_0 Heparinase II/III-like protein - - - 9.362e-253 811.0
SHD1_k127_1401037_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 617.0
SHD1_k127_1401037_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 369.0
SHD1_k127_1401037_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 333.0
SHD1_k127_1401037_4 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 306.0
SHD1_k127_1401037_5 SpoU rRNA Methylase family K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 298.0
SHD1_k127_1401037_6 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000008363 159.0
SHD1_k127_1420078_0 PFAM NAD dependent epimerase dehydratase family K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 556.0
SHD1_k127_1420078_1 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 340.0
SHD1_k127_1420078_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000252 284.0
SHD1_k127_1420078_3 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000001324 235.0
SHD1_k127_1420078_4 COGs COG3307 Lipid A core - O-antigen ligase - - - 0.00000000000000000000000000000000000000000000000000003018 205.0
SHD1_k127_1420078_5 G-rich domain on putative tyrosine kinase - - - 0.0000000000000000000000000000000000000000000003023 191.0
SHD1_k127_1430578_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 508.0
SHD1_k127_1430578_1 - K00241 - - 0.0000000000000000000000000000000000000000000000000000000003988 213.0
SHD1_k127_1442249_0 PFAM Glycoside hydrolase 15-related - - - 2.827e-277 889.0
SHD1_k127_1442249_1 Glycosyltransferase 36 associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 354.0
SHD1_k127_1442249_2 Binding-protein-dependent transport system inner membrane component K05815 - - 0.00000000000000000001811 91.0
SHD1_k127_1443804_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 419.0
SHD1_k127_1443804_1 ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000007934 190.0
SHD1_k127_1443804_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000006258 128.0
SHD1_k127_1443804_3 protein kinase activity - - - 0.00000000000000000004153 102.0
SHD1_k127_1447645_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 383.0
SHD1_k127_1447645_1 ECF sigma factor - - - 0.00007671 46.0
SHD1_k127_1457597_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.955e-219 688.0
SHD1_k127_1457597_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 598.0
SHD1_k127_1457597_2 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 326.0
SHD1_k127_1457597_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 316.0
SHD1_k127_1457597_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 289.0
SHD1_k127_1457597_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000134 247.0
SHD1_k127_1457597_6 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000007645 184.0
SHD1_k127_1459931_0 Tricorn protease homolog K08676 - - 7.041e-297 927.0
SHD1_k127_1459931_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 5.568e-275 859.0
SHD1_k127_1459931_2 Dienelactone hydrolase family - - - 1.998e-241 787.0
SHD1_k127_1459931_3 Malate synthase K01638 - 2.3.3.9 5.087e-206 659.0
SHD1_k127_1459931_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 457.0
SHD1_k127_1459931_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
SHD1_k127_1459931_6 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 349.0
SHD1_k127_1459931_7 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 294.0
SHD1_k127_1459931_8 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000003647 226.0
SHD1_k127_1459931_9 mRNA catabolic process K06950 - - 0.00000000000000000000000000000000000000000000001109 188.0
SHD1_k127_1465246_2 - - - - 0.000003752 49.0
SHD1_k127_1475419_0 ABC transporter K06020 - 3.6.3.25 7.434e-256 800.0
SHD1_k127_1475419_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000125 141.0
SHD1_k127_149200_0 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 446.0
SHD1_k127_149200_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 327.0
SHD1_k127_149200_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000001454 226.0
SHD1_k127_149200_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000007751 188.0
SHD1_k127_149200_4 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000000001398 168.0
SHD1_k127_149200_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000000005397 101.0
SHD1_k127_149200_6 Domain of unknown function (DUF4440) - - - 0.0000000000003157 78.0
SHD1_k127_1499581_0 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 3.312e-194 631.0
SHD1_k127_1499581_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
SHD1_k127_1499581_2 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 316.0
SHD1_k127_1499581_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000001953 233.0
SHD1_k127_1505386_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 325.0
SHD1_k127_1505386_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000002716 151.0
SHD1_k127_1505386_2 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000001373 144.0
SHD1_k127_1505386_3 - - - - 0.0000000000000000000002072 101.0
SHD1_k127_1505386_6 - - - - 0.00000000000001308 78.0
SHD1_k127_1519427_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 302.0
SHD1_k127_1519427_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
SHD1_k127_1519427_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000006973 130.0
SHD1_k127_1529094_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 500.0
SHD1_k127_1529094_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 370.0
SHD1_k127_1529094_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 358.0
SHD1_k127_1529094_3 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 338.0
SHD1_k127_1529094_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008102 251.0
SHD1_k127_1529094_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000001454 248.0
SHD1_k127_1529094_6 - - - - 0.0000000000000000003293 92.0
SHD1_k127_1529094_7 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000001357 90.0
SHD1_k127_1549425_0 TonB dependent receptor - - - 3.229e-250 807.0
SHD1_k127_1549425_1 peptidase K01415,K07386 - 3.4.24.71 5.014e-203 658.0
SHD1_k127_1549425_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000002297 192.0
SHD1_k127_1549425_3 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000006972 192.0
SHD1_k127_1549425_4 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000000567 123.0
SHD1_k127_1549425_5 - - - - 0.00000000000001189 77.0
SHD1_k127_1549425_6 Aldehyde dehydrogenase - - - 0.000004673 49.0
SHD1_k127_1584469_0 PFAM Alcohol dehydrogenase - - - 1.176e-198 623.0
SHD1_k127_1584469_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 591.0
SHD1_k127_1584469_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 520.0
SHD1_k127_1584469_3 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 349.0
SHD1_k127_1584469_4 - - - - 0.00000000000000000000000000000000000000002689 161.0
SHD1_k127_1584469_5 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000001004 115.0
SHD1_k127_1587982_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate K03701 - - 0.0 1332.0
SHD1_k127_1587982_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 378.0
SHD1_k127_1587982_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000001459 202.0
SHD1_k127_1599237_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 3.078e-305 955.0
SHD1_k127_1599237_1 GlcNAc-PI de-N-acetylase - - - 2.442e-228 732.0
SHD1_k127_1600934_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 463.0
SHD1_k127_1603780_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1035.0
SHD1_k127_1614137_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1386.0
SHD1_k127_1614137_1 WD40-like Beta Propeller Repeat - - - 1.328e-240 775.0
SHD1_k127_1614137_10 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000002125 192.0
SHD1_k127_1614137_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000006631 195.0
SHD1_k127_1614137_12 Phospholipase D Transphosphatidylase K06131,K06132,K06915 - - 0.000000000000000000000000000000000000000000000000007956 201.0
SHD1_k127_1614137_13 acr, cog1993 K09137 - - 0.00000000000000000000000000000000008246 143.0
SHD1_k127_1614137_14 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000006536 115.0
SHD1_k127_1614137_2 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 499.0
SHD1_k127_1614137_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 451.0
SHD1_k127_1614137_4 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 428.0
SHD1_k127_1614137_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 417.0
SHD1_k127_1614137_6 Ectoine utilization protein EutC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001088 271.0
SHD1_k127_1614137_7 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001276 285.0
SHD1_k127_1614137_8 carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000001224 214.0
SHD1_k127_1614137_9 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000000000000000000145 205.0
SHD1_k127_1616066_0 cobalamin-transporting ATPase activity K02014 - - 0.00000000000000000000000000000000000009686 162.0
SHD1_k127_1616066_1 virion core protein, lumpy skin disease virus - - - 0.000000000001937 69.0
SHD1_k127_1617235_0 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 601.0
SHD1_k127_1617235_1 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 373.0
SHD1_k127_1617235_10 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000006493 151.0
SHD1_k127_1617235_11 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.000000000000000000000000008034 121.0
SHD1_k127_1617235_12 lyase activity K09733 - 4.2.3.153 0.0000000000000000006313 96.0
SHD1_k127_1617235_13 EthD domain - - - 0.00000000000000001503 93.0
SHD1_k127_1617235_2 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 310.0
SHD1_k127_1617235_3 Belongs to the RimK family K05827,K05844 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 301.0
SHD1_k127_1617235_4 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000004611 239.0
SHD1_k127_1617235_5 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000000000006253 226.0
SHD1_k127_1617235_6 formylmethanofuran dehydrogenase, subunit K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000002027 231.0
SHD1_k127_1617235_7 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000000000000000000002746 196.0
SHD1_k127_1617235_8 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000005307 164.0
SHD1_k127_1617235_9 ATP-grasp domain K01499,K06913 - 3.5.4.27 0.000000000000000000000000000000000000001797 157.0
SHD1_k127_161762_0 Acts as a magnesium transporter K06213 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 526.0
SHD1_k127_161762_1 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 370.0
SHD1_k127_161762_2 membrane transporter protein K07090 - - 0.00000000239 62.0
SHD1_k127_161762_3 - - - - 0.0000002482 55.0
SHD1_k127_1620498_0 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 392.0
SHD1_k127_1620498_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 291.0
SHD1_k127_1620498_2 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000004833 252.0
SHD1_k127_1620498_3 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000004171 143.0
SHD1_k127_1625330_0 secondary active sulfate transmembrane transporter activity - - - 5.945e-277 878.0
SHD1_k127_1625330_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 576.0
SHD1_k127_1625330_2 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 494.0
SHD1_k127_1625330_3 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 370.0
SHD1_k127_1625330_4 Alpha beta hydrolase K06049 - - 0.00000000000000000000000000000000000000000000000000000000000000003827 239.0
SHD1_k127_1625330_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000001171 125.0
SHD1_k127_1625330_6 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000741 121.0
SHD1_k127_1625330_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000003519 97.0
SHD1_k127_1625330_8 Cytochrome c - - - 0.00000000000391 67.0
SHD1_k127_1645370_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
SHD1_k127_1645370_1 DNA modification repair radical SAM protein - - - 0.0000000000000000000000000000000000000000000000002844 189.0
SHD1_k127_1645370_2 ATP dependent DNA ligase C terminal region - - - 0.00000000000000000000000000000000000000000008449 163.0
SHD1_k127_165909_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.181e-205 647.0
SHD1_k127_165909_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 601.0
SHD1_k127_165909_2 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006998 259.0
SHD1_k127_165909_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000006519 177.0
SHD1_k127_1664739_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 578.0
SHD1_k127_1664739_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 530.0
SHD1_k127_1664739_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 497.0
SHD1_k127_1664739_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 389.0
SHD1_k127_1664739_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 369.0
SHD1_k127_1664739_5 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000000000000000000000000008656 220.0
SHD1_k127_1664739_6 - - - - 0.000000000000000000000000001261 115.0
SHD1_k127_1664739_8 FG-GAP repeat protein - - - 0.00008611 53.0
SHD1_k127_1665588_0 Major facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 586.0
SHD1_k127_1665588_1 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 518.0
SHD1_k127_1665588_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 322.0
SHD1_k127_1665588_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006621 282.0
SHD1_k127_1665588_4 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000009244 257.0
SHD1_k127_1665588_5 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.000000000000000000000000000000000000000003865 159.0
SHD1_k127_1668435_0 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 569.0
SHD1_k127_1668435_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 558.0
SHD1_k127_1668435_2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000003238 162.0
SHD1_k127_1668435_3 - - - - 0.00000000000000000000000000000002769 127.0
SHD1_k127_1668435_4 - - - - 0.000000001415 61.0
SHD1_k127_1668435_5 - - - - 0.000001954 56.0
SHD1_k127_1669691_0 DEAD/H associated K03724 - - 0.0 1143.0
SHD1_k127_1669691_1 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 436.0
SHD1_k127_1669691_2 Replication initiator protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 359.0
SHD1_k127_1669691_3 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000005974 160.0
SHD1_k127_1669691_4 - - - - 0.0000000000000001253 81.0
SHD1_k127_1678431_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 323.0
SHD1_k127_1678431_1 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000005133 167.0
SHD1_k127_1678431_2 Phosphotransferase System K11189 - - 0.000000000000000000000000000000000004447 140.0
SHD1_k127_1678431_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000001382 100.0
SHD1_k127_1683451_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000003406 222.0
SHD1_k127_1683451_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000001217 177.0
SHD1_k127_1683451_2 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000001423 131.0
SHD1_k127_1698140_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 421.0
SHD1_k127_1698140_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 317.0
SHD1_k127_1698140_2 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 310.0
SHD1_k127_1698140_3 - - - - 0.00000000000000000000000000000000000000000000436 171.0
SHD1_k127_1698140_4 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000002844 160.0
SHD1_k127_1698140_5 membrane K11622 - - 0.00000000000000000000000000001043 127.0
SHD1_k127_1699028_0 trisaccharide binding - - - 8.075e-196 641.0
SHD1_k127_1699028_1 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 624.0
SHD1_k127_1699028_2 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 447.0
SHD1_k127_1699028_3 DoxX - - - 0.000000000000000000000000000000000000000001394 163.0
SHD1_k127_1699028_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001671 148.0
SHD1_k127_1699028_5 Cupin domain - - - 0.0000000000000000000000000000000000002458 144.0
SHD1_k127_1699028_6 acetyltransferase K03827 - - 0.000000000000000000000000000006093 126.0
SHD1_k127_1699028_7 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000007369 108.0
SHD1_k127_1699028_8 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000005689 59.0
SHD1_k127_1699028_9 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00004389 46.0
SHD1_k127_17069_0 hydrolase activity, acting on ester bonds K07017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 299.0
SHD1_k127_17069_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000003234 198.0
SHD1_k127_17069_2 Rhodanese Homology Domain - - - 0.0000000006316 66.0
SHD1_k127_1713719_0 ABC transporter K06020 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 557.0
SHD1_k127_1713719_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 508.0
SHD1_k127_1713719_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000297 197.0
SHD1_k127_1713719_3 - - - - 0.0000000000000000000000000000000000000004381 153.0
SHD1_k127_1724019_0 efflux transmembrane transporter activity - - - 4.139e-228 737.0
SHD1_k127_1724019_1 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000001797 126.0
SHD1_k127_1724019_2 Belongs to the ompA family - - - 0.0000000001173 70.0
SHD1_k127_1727529_0 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 323.0
SHD1_k127_1727529_1 Putative modulator of DNA gyrase K03568 - - 0.00002795 50.0
SHD1_k127_172841_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 484.0
SHD1_k127_172841_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 476.0
SHD1_k127_172841_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 357.0
SHD1_k127_172841_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001513 235.0
SHD1_k127_172841_4 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000001568 104.0
SHD1_k127_172898_0 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 566.0
SHD1_k127_172898_1 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 454.0
SHD1_k127_172898_10 Predicted membrane protein (DUF2339) - - - 0.00001012 59.0
SHD1_k127_172898_2 RDD family K06384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 469.0
SHD1_k127_172898_3 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 438.0
SHD1_k127_172898_4 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 344.0
SHD1_k127_172898_5 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 290.0
SHD1_k127_172898_6 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000003064 233.0
SHD1_k127_172898_8 RF-1 domain K15034 - - 0.00000000000000000000000000000004383 144.0
SHD1_k127_1729764_0 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 538.0
SHD1_k127_1729764_1 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000001222 217.0
SHD1_k127_1729764_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000002411 162.0
SHD1_k127_1737208_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 9.722e-199 631.0
SHD1_k127_1737208_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 493.0
SHD1_k127_1737208_2 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 484.0
SHD1_k127_1737208_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 478.0
SHD1_k127_1737208_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 363.0
SHD1_k127_1737208_5 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000353 273.0
SHD1_k127_1737208_6 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000003897 224.0
SHD1_k127_1737208_7 FAD binding domain K11472 - - 0.000000000000000000000000000000000000003706 156.0
SHD1_k127_174829_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 512.0
SHD1_k127_174829_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 475.0
SHD1_k127_174829_10 - - - - 0.00000000000000001098 90.0
SHD1_k127_174829_11 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000002695 71.0
SHD1_k127_174829_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000004748 56.0
SHD1_k127_174829_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 389.0
SHD1_k127_174829_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 355.0
SHD1_k127_174829_4 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 338.0
SHD1_k127_174829_5 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 310.0
SHD1_k127_174829_6 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002363 256.0
SHD1_k127_174829_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000008025 184.0
SHD1_k127_174829_8 Intracellular proteinase inhibitor - - - 0.0000000000000000000000000000000121 133.0
SHD1_k127_174829_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000005705 95.0
SHD1_k127_1756753_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000006087 156.0
SHD1_k127_1756753_1 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.0000000000000000114 85.0
SHD1_k127_1756753_2 WD40-like Beta Propeller Repeat - - - 0.000000001694 61.0
SHD1_k127_1759674_0 - - - - 0.000000000000000000000000000000000000000000000000008599 186.0
SHD1_k127_1759674_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000008107 143.0
SHD1_k127_1759674_2 - - - - 0.000000000000000000000000000001427 132.0
SHD1_k127_1759674_3 - - - - 0.0000000003752 66.0
SHD1_k127_1759674_4 - - - - 0.000001141 55.0
SHD1_k127_176008_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 5.679e-287 935.0
SHD1_k127_176008_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 464.0
SHD1_k127_176008_10 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001652 280.0
SHD1_k127_176008_11 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000001558 219.0
SHD1_k127_176008_12 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000001245 216.0
SHD1_k127_176008_13 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000001088 199.0
SHD1_k127_176008_14 CYTH domain K01768,K05873 - 4.6.1.1 0.00000000000000000000000000000000000000001248 160.0
SHD1_k127_176008_15 - - - - 0.0000000000000000000000000000000000000000221 162.0
SHD1_k127_176008_16 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000001143 154.0
SHD1_k127_176008_17 - - - - 0.00000000000000000000009 108.0
SHD1_k127_176008_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000004145 102.0
SHD1_k127_176008_19 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000002944 79.0
SHD1_k127_176008_2 Flavin-binding monooxygenase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 466.0
SHD1_k127_176008_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 458.0
SHD1_k127_176008_4 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 426.0
SHD1_k127_176008_5 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 387.0
SHD1_k127_176008_6 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 369.0
SHD1_k127_176008_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 312.0
SHD1_k127_176008_8 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 309.0
SHD1_k127_176008_9 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 297.0
SHD1_k127_177115_0 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 311.0
SHD1_k127_177115_1 E1-E2 ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000009552 251.0
SHD1_k127_177115_2 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000001113 241.0
SHD1_k127_177115_3 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000000001611 157.0
SHD1_k127_177115_4 lysyltransferase activity - - - 0.000000000001706 79.0
SHD1_k127_1795426_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003754 276.0
SHD1_k127_1795426_1 ABC transporter K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005855 271.0
SHD1_k127_1802030_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 336.0
SHD1_k127_1802030_1 Tricorn protease C1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001188 270.0
SHD1_k127_1841487_0 FMN-dependent dehydrogenase K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 561.0
SHD1_k127_1841487_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000001165 180.0
SHD1_k127_1841487_2 - - - - 0.00000000000000000000000000000000000000002899 160.0
SHD1_k127_1841487_3 DinB superfamily - - - 0.00000000000000000000000000000029 134.0
SHD1_k127_1844711_0 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 7.959e-292 910.0
SHD1_k127_1844711_1 alginic acid biosynthetic process K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 379.0
SHD1_k127_1844711_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000008668 229.0
SHD1_k127_1844711_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000001439 238.0
SHD1_k127_1844711_4 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000003757 224.0
SHD1_k127_1844711_5 Haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000002581 201.0
SHD1_k127_1844711_6 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000000000000000000009361 206.0
SHD1_k127_1844711_7 - - - - 0.000000000000000000000000000002213 132.0
SHD1_k127_1851680_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001065 282.0
SHD1_k127_1859210_0 Glycosyl transferase family group 2 - - - 2.124e-256 816.0
SHD1_k127_1859210_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00694,K11936,K20541 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 618.0
SHD1_k127_1859210_10 Pilus assembly protein PilX K02673 - - 0.0006973 45.0
SHD1_k127_1859210_2 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 552.0
SHD1_k127_1859210_3 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 351.0
SHD1_k127_1859210_4 macromolecule localization K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 302.0
SHD1_k127_1859210_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001174 277.0
SHD1_k127_1859210_6 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002993 250.0
SHD1_k127_1859210_7 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000008106 213.0
SHD1_k127_1859210_8 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000004199 129.0
SHD1_k127_1859210_9 Tetratricopeptide repeat - - - 0.000000000000000007134 94.0
SHD1_k127_1859514_0 cellulose binding - - - 0.0 1181.0
SHD1_k127_1859514_1 Insulinase (Peptidase family M16) K07263 - - 6.962e-207 655.0
SHD1_k127_1859514_2 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 528.0
SHD1_k127_1859514_3 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 432.0
SHD1_k127_1862266_0 Glyoxal oxidase N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 364.0
SHD1_k127_1862266_1 - - - - 0.00000000000000000001586 98.0
SHD1_k127_1862266_2 - - - - 0.00000000000000002355 84.0
SHD1_k127_1863008_0 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity K02778,K02779,K20116,K20117,K20118 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009401,GO:0015144,GO:0015749,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090564,GO:1904659 2.7.1.199 3.402e-260 813.0
SHD1_k127_1863008_1 Trehalase K01194 - 3.2.1.28 4.139e-221 699.0
SHD1_k127_1863008_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 298.0
SHD1_k127_1863008_3 Tetratricopeptide repeat - - - 0.0000000000000000003143 94.0
SHD1_k127_1863008_4 - - - - 0.000000000000001004 79.0
SHD1_k127_1866361_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1030.0
SHD1_k127_1866361_1 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 474.0
SHD1_k127_1866361_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 456.0
SHD1_k127_1866361_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 408.0
SHD1_k127_1866361_4 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 298.0
SHD1_k127_1866361_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001735 278.0
SHD1_k127_1866361_6 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000005479 239.0
SHD1_k127_1866361_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000004313 145.0
SHD1_k127_1866361_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000001001 133.0
SHD1_k127_1866361_9 - - - - 0.0000000000000000000000000006395 119.0
SHD1_k127_1866919_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 440.0
SHD1_k127_1866919_1 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 326.0
SHD1_k127_1866919_2 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 317.0
SHD1_k127_1866919_3 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 305.0
SHD1_k127_1907452_0 SPTR Glycosyl hydrolase, BNR repeat-containing protein - - - 3.558e-295 936.0
SHD1_k127_1907452_1 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 386.0
SHD1_k127_1909608_0 Uncharacterized protein family (UPF0051) K09014 - - 3.952e-195 611.0
SHD1_k127_1909608_1 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 530.0
SHD1_k127_1909608_10 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000007829 157.0
SHD1_k127_1909608_11 cyclic nucleotide binding K10914,K21563 - - 0.00000000000000000000000000000000003043 143.0
SHD1_k127_1909608_13 PFAM regulatory protein LysR K02019 - - 0.000000004642 64.0
SHD1_k127_1909608_14 Phosphate-selective porin O and P - - - 0.0002096 53.0
SHD1_k127_1909608_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 414.0
SHD1_k127_1909608_3 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 394.0
SHD1_k127_1909608_4 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 342.0
SHD1_k127_1909608_5 tungstate binding K15495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008375 266.0
SHD1_k127_1909608_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001973 231.0
SHD1_k127_1909608_7 Protein of unknown function (DUF1761) - - - 0.00000000000000000000000000000000000000000000000000000000000188 211.0
SHD1_k127_1909608_8 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000000001914 207.0
SHD1_k127_1909608_9 Predicted membrane protein (DUF2243) - - - 0.0000000000000000000000000000000000000000002122 164.0
SHD1_k127_1923917_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 464.0
SHD1_k127_1923917_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 414.0
SHD1_k127_1923917_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 312.0
SHD1_k127_1923917_3 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 297.0
SHD1_k127_1923917_4 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 295.0
SHD1_k127_1923917_5 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000186 232.0
SHD1_k127_1923917_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000551 126.0
SHD1_k127_1941583_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000002385 83.0
SHD1_k127_1948388_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001775 244.0
SHD1_k127_1948388_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000003664 240.0
SHD1_k127_1948388_2 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000002384 100.0
SHD1_k127_1956592_0 Carbohydrate family 9 binding domain-like - - - 1.642e-242 777.0
SHD1_k127_195874_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 3.488e-269 839.0
SHD1_k127_195874_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.125e-249 795.0
SHD1_k127_195874_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.338e-221 701.0
SHD1_k127_195874_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.299e-214 670.0
SHD1_k127_195874_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 533.0
SHD1_k127_195874_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 496.0
SHD1_k127_195874_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000241 260.0
SHD1_k127_195874_7 PFAM amino acid-binding ACT domain protein K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000004907 187.0
SHD1_k127_1969992_0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 407.0
SHD1_k127_1969992_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 375.0
SHD1_k127_1969992_10 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000001701 77.0
SHD1_k127_1969992_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 295.0
SHD1_k127_1969992_3 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000009008 201.0
SHD1_k127_1969992_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000001398 189.0
SHD1_k127_1969992_5 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000002534 178.0
SHD1_k127_1969992_6 acetyltransferase K18816 - 2.3.1.82 0.000000000000000000000000000000000000003815 150.0
SHD1_k127_1969992_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000002005 130.0
SHD1_k127_1969992_8 Glycosyltransferase like family 2 - - - 0.000000000000000000000000003286 124.0
SHD1_k127_1969992_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000004766 93.0
SHD1_k127_1970313_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 309.0
SHD1_k127_1970313_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001366 249.0
SHD1_k127_1970313_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000026 210.0
SHD1_k127_1970313_3 OmpA family - - - 0.00000000000000000000000000000000000000000000000000007453 195.0
SHD1_k127_1970313_4 Peptidase inhibitor I9 - - - 0.000000000000000000000000000000000000000000002153 181.0
SHD1_k127_1970313_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000004481 75.0
SHD1_k127_1970313_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000001241 79.0
SHD1_k127_1981072_0 Peptidase dimerisation domain - - - 3.817e-212 673.0
SHD1_k127_1981072_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 494.0
SHD1_k127_1981072_2 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 297.0
SHD1_k127_1981072_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 309.0
SHD1_k127_1981072_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000004542 138.0
SHD1_k127_1984266_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 578.0
SHD1_k127_1984266_1 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000273 289.0
SHD1_k127_1984266_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001619 270.0
SHD1_k127_1984266_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000001898 214.0
SHD1_k127_1984266_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000127 64.0
SHD1_k127_1984266_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 0.0000002247 53.0
SHD1_k127_1987994_0 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000009874 242.0
SHD1_k127_199925_0 -O-antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 377.0
SHD1_k127_199925_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000003449 261.0
SHD1_k127_199925_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000008931 183.0
SHD1_k127_199925_3 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000005622 149.0
SHD1_k127_199925_4 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000000000000000000000002003 143.0
SHD1_k127_199925_5 - - - - 0.000000000000000001589 94.0
SHD1_k127_199925_6 Rhomboid family K07059 - - 0.00000000000000005488 84.0
SHD1_k127_199925_7 - - - - 0.00000000002125 72.0
SHD1_k127_199925_9 Domain of Unknown Function (DUF350) - - - 0.0000005483 56.0
SHD1_k127_2001031_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.103e-212 668.0
SHD1_k127_2001031_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 429.0
SHD1_k127_2001031_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 361.0
SHD1_k127_2001031_3 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001603 275.0
SHD1_k127_2001031_4 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000000000000002455 228.0
SHD1_k127_2001031_5 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000007455 162.0
SHD1_k127_2001031_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000009977 158.0
SHD1_k127_2001031_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000001035 104.0
SHD1_k127_2007259_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 1.588e-296 928.0
SHD1_k127_2007259_1 AMP-binding enzyme C-terminal domain K00666 - - 1.059e-246 771.0
SHD1_k127_2007259_10 zinc ion binding K04477,K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 304.0
SHD1_k127_2007259_11 - - - - 0.00000000000000000000000000000000000000000000000001723 186.0
SHD1_k127_2007259_12 Serine aminopeptidase, S33 - - - 0.0000000000000003788 89.0
SHD1_k127_2007259_14 Aminotransferase class-V - - - 0.0000008834 50.0
SHD1_k127_2007259_2 Sigma-54 interaction domain - - - 3.004e-195 617.0
SHD1_k127_2007259_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 551.0
SHD1_k127_2007259_4 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 418.0
SHD1_k127_2007259_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 400.0
SHD1_k127_2007259_6 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 399.0
SHD1_k127_2007259_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 384.0
SHD1_k127_2007259_8 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 329.0
SHD1_k127_2007259_9 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 325.0
SHD1_k127_2025239_0 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 386.0
SHD1_k127_2025239_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000003493 224.0
SHD1_k127_2025239_2 Sporulation related domain - - - 0.000000000000000000000000000000000579 145.0
SHD1_k127_2033440_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 565.0
SHD1_k127_2033440_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000301 192.0
SHD1_k127_2033440_2 - - - - 0.0000000000000000000000000000000005696 143.0
SHD1_k127_2033440_3 Septum formation initiator K05589 - - 0.00000000000000000000000004683 110.0
SHD1_k127_2033440_4 - - - - 0.000000006656 65.0
SHD1_k127_2033440_5 - - - - 0.000001563 54.0
SHD1_k127_2052747_0 Protein kinase domain K12132 - 2.7.11.1 7.372e-194 617.0
SHD1_k127_2052747_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001832 291.0
SHD1_k127_2052747_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000001531 109.0
SHD1_k127_2058113_0 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 526.0
SHD1_k127_2058113_1 Glucose inhibited division protein A K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 419.0
SHD1_k127_2058113_2 ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 336.0
SHD1_k127_2058113_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 328.0
SHD1_k127_2058113_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000001586 224.0
SHD1_k127_2058113_5 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000001875 219.0
SHD1_k127_2058113_6 - - - - 0.00000000000001793 85.0
SHD1_k127_2058113_7 anti-sigma factor - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.000000000549 65.0
SHD1_k127_2062479_0 Insulinase (Peptidase family M16) - - - 5.259e-205 646.0
SHD1_k127_2062479_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 523.0
SHD1_k127_2062479_2 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 345.0
SHD1_k127_2062479_3 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 336.0
SHD1_k127_2062479_4 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
SHD1_k127_2062479_5 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000002654 242.0
SHD1_k127_2062479_6 PFAM Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000009766 237.0
SHD1_k127_2062479_7 Protein of unknown function (DUF1464) - - - 0.0000000000000000000000000009153 118.0
SHD1_k127_2062479_8 - - - - 0.000000000000001963 87.0
SHD1_k127_2070495_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 3.711e-229 716.0
SHD1_k127_2070495_1 metalloendopeptidase activity K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 559.0
SHD1_k127_2070495_10 - - - - 0.00000005045 64.0
SHD1_k127_2070495_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 489.0
SHD1_k127_2070495_3 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 491.0
SHD1_k127_2070495_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
SHD1_k127_2070495_5 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003311 265.0
SHD1_k127_2070495_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006595 259.0
SHD1_k127_2070495_7 - - - - 0.00000000000000000000000000003695 119.0
SHD1_k127_2070495_8 - - - - 0.000000000000001068 83.0
SHD1_k127_2070495_9 - - - - 0.00000000000249 72.0
SHD1_k127_2072064_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000004216 159.0
SHD1_k127_2072064_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000002486 151.0
SHD1_k127_2072064_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000002883 131.0
SHD1_k127_20829_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 383.0
SHD1_k127_20829_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 316.0
SHD1_k127_20829_2 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000002223 254.0
SHD1_k127_20829_3 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000003406 233.0
SHD1_k127_2085271_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000001953 250.0
SHD1_k127_2085271_1 - - - - 0.0000000000000000000000000000000000000000000006321 185.0
SHD1_k127_2085271_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000001693 150.0
SHD1_k127_2085271_3 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000001006 108.0
SHD1_k127_2086929_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.006e-205 647.0
SHD1_k127_2086929_1 Arginosuccinate synthase K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 464.0
SHD1_k127_2086929_10 von Willebrand factor (vWF) type A domain - - - 0.000000000000000003913 95.0
SHD1_k127_2086929_11 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000389 53.0
SHD1_k127_2086929_12 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000006028 59.0
SHD1_k127_2086929_13 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.00002307 55.0
SHD1_k127_2086929_2 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 466.0
SHD1_k127_2086929_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009365 247.0
SHD1_k127_2086929_4 Arginosuccinate synthase K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000003425 186.0
SHD1_k127_2086929_5 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000000000000000000006897 173.0
SHD1_k127_2086929_6 protein tyrosine kinase activity K16692 - - 0.0000000000000000000000000000000000000000002237 173.0
SHD1_k127_2086929_7 - - - - 0.0000000000000000000000000000000000000008578 154.0
SHD1_k127_2086929_8 Cold shock protein domain K03704 - - 0.0000000000000000000000000000000000781 135.0
SHD1_k127_2086929_9 - - - - 0.00000000000000000000005277 104.0
SHD1_k127_2087570_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.249e-278 879.0
SHD1_k127_2087570_1 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 601.0
SHD1_k127_2087570_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 466.0
SHD1_k127_2097130_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1217.0
SHD1_k127_2097130_1 4Fe-4S single cluster domain K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 392.0
SHD1_k127_2097130_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 379.0
SHD1_k127_2101286_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 3.615e-194 624.0
SHD1_k127_2101286_1 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 442.0
SHD1_k127_2101286_2 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 366.0
SHD1_k127_2101286_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000009094 263.0
SHD1_k127_2101286_4 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000184 100.0
SHD1_k127_2107797_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 8.246e-261 809.0
SHD1_k127_2107797_1 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 426.0
SHD1_k127_2107797_2 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 400.0
SHD1_k127_2107797_3 Domain of unknown function DUF21 K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006125 258.0
SHD1_k127_2107797_4 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000005316 193.0
SHD1_k127_2107797_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000415 154.0
SHD1_k127_2113481_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 515.0
SHD1_k127_2113481_1 protocatechuate 3,4-dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 384.0
SHD1_k127_2113481_10 Protein of unknown function (DUF3761) - - - 0.000005756 55.0
SHD1_k127_2113481_2 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 337.0
SHD1_k127_2113481_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 292.0
SHD1_k127_2113481_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004307 282.0
SHD1_k127_2113481_5 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001424 290.0
SHD1_k127_2113481_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002924 265.0
SHD1_k127_2113481_7 YtkA-like - - - 0.00000000000000000000000000000000000000000000000000002668 192.0
SHD1_k127_2113481_8 - - - - 0.000000000000000005189 87.0
SHD1_k127_2113481_9 - - - - 0.00000008931 60.0
SHD1_k127_2117509_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1568.0
SHD1_k127_2117509_1 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 345.0
SHD1_k127_2117509_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000003139 195.0
SHD1_k127_2118406_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1095.0
SHD1_k127_2118406_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 4.897e-200 632.0
SHD1_k127_2118406_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 521.0
SHD1_k127_2118406_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000003229 186.0
SHD1_k127_2118406_4 Protein of unknown function (DUF494) K03747 - - 0.00000000000000000002884 92.0
SHD1_k127_2118406_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000006397 91.0
SHD1_k127_2121758_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 354.0
SHD1_k127_2121758_1 Transport permease protein - - - 0.00000000000000000000000000000000000000000000000000000008177 209.0
SHD1_k127_2121758_2 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000002952 136.0
SHD1_k127_213293_0 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 4.074e-195 620.0
SHD1_k127_213293_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001645 275.0
SHD1_k127_213293_2 trehalose biosynthetic process K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000006974 206.0
SHD1_k127_213293_3 - - - - 0.00000000001059 70.0
SHD1_k127_2145940_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 495.0
SHD1_k127_2145940_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000001542 219.0
SHD1_k127_2151761_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 2.849e-252 788.0
SHD1_k127_2151761_1 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001116 248.0
SHD1_k127_2151761_2 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000003247 169.0
SHD1_k127_2159237_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 531.0
SHD1_k127_2159237_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 432.0
SHD1_k127_2159237_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 378.0
SHD1_k127_2159237_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 369.0
SHD1_k127_2159237_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 337.0
SHD1_k127_2159237_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000001024 200.0
SHD1_k127_2159237_6 Preprotein translocase subunit K03210 - - 0.0000000000000000000000001301 113.0
SHD1_k127_2159237_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000001385 99.0
SHD1_k127_2159237_8 CHAT domain - - - 0.0000000000005483 80.0
SHD1_k127_2161248_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 507.0
SHD1_k127_2161248_1 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 496.0
SHD1_k127_2161248_2 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 469.0
SHD1_k127_2161248_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004159 261.0
SHD1_k127_2161248_4 Protein of unknown function (DUF4199) - - - 0.0000000000000000000000000000000000000000000000000000000006178 207.0
SHD1_k127_2161248_5 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000002763 203.0
SHD1_k127_2161248_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000242 196.0
SHD1_k127_2161248_7 - - - - 0.00000000000000000000000000000000000000159 162.0
SHD1_k127_2161248_8 Histidine kinase K07675 - 2.7.13.3 0.000000000001239 79.0
SHD1_k127_2161248_9 cellulose binding - - - 0.00005047 47.0
SHD1_k127_2161412_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 3.399e-232 739.0
SHD1_k127_2161412_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 492.0
SHD1_k127_2161412_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 487.0
SHD1_k127_2161412_3 Peptidase family M20/M25/M40 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 458.0
SHD1_k127_2161412_4 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 387.0
SHD1_k127_2161412_5 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 404.0
SHD1_k127_2161412_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 337.0
SHD1_k127_2161412_7 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000001797 180.0
SHD1_k127_2161412_8 YCII-related domain - - - 0.000000000000000000000000000000000004632 140.0
SHD1_k127_2161412_9 efflux transmembrane transporter activity K12340 - - 0.0000000000000000000000000000002082 133.0
SHD1_k127_2168185_0 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 480.0
SHD1_k127_2168185_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 351.0
SHD1_k127_2168185_2 DNA primase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
SHD1_k127_2168185_3 - - - - 0.0000000000000000000000004361 113.0
SHD1_k127_2168185_4 DNA primase activity - - - 0.0000000000005183 75.0
SHD1_k127_2168555_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 6.794e-240 751.0
SHD1_k127_2168555_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 489.0
SHD1_k127_2168555_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000009512 78.0
SHD1_k127_2168555_2 Competence-damaged protein K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 492.0
SHD1_k127_2168555_3 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 467.0
SHD1_k127_2168555_4 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 382.0
SHD1_k127_2168555_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003006 285.0
SHD1_k127_2168555_6 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
SHD1_k127_2168555_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000001603 231.0
SHD1_k127_2168555_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000001089 194.0
SHD1_k127_2168555_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000002254 134.0
SHD1_k127_2172747_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 606.0
SHD1_k127_2172747_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 426.0
SHD1_k127_2172747_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000653 167.0
SHD1_k127_2172747_3 - - - - 0.0000000000001963 76.0
SHD1_k127_2182367_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 4.424e-271 840.0
SHD1_k127_2182367_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000006931 186.0
SHD1_k127_2182367_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000001464 113.0
SHD1_k127_2183699_0 Atp-dependent helicase - - - 0.0 1179.0
SHD1_k127_2183699_1 Zinc carboxypeptidase - - - 8.44e-295 925.0
SHD1_k127_2183699_10 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 393.0
SHD1_k127_2183699_11 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 382.0
SHD1_k127_2183699_12 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 359.0
SHD1_k127_2183699_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 332.0
SHD1_k127_2183699_14 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 297.0
SHD1_k127_2183699_15 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 296.0
SHD1_k127_2183699_16 GTP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004312 265.0
SHD1_k127_2183699_17 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000000000000000000000000000000002939 218.0
SHD1_k127_2183699_18 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000002809 195.0
SHD1_k127_2183699_19 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000007325 201.0
SHD1_k127_2183699_2 Nicastrin K01301 - 3.4.17.21 5.211e-277 877.0
SHD1_k127_2183699_20 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000007205 182.0
SHD1_k127_2183699_21 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000001325 186.0
SHD1_k127_2183699_22 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000005415 151.0
SHD1_k127_2183699_23 chaperone-mediated protein folding - - - 0.000000000000000000000000000005826 132.0
SHD1_k127_2183699_24 Thioesterase superfamily K07107 - - 0.00000000000000000000000000199 116.0
SHD1_k127_2183699_26 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000004234 100.0
SHD1_k127_2183699_27 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.00000000000000000003345 103.0
SHD1_k127_2183699_28 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000009591 96.0
SHD1_k127_2183699_29 - - - - 0.000000000000008115 85.0
SHD1_k127_2183699_3 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 9.123e-234 742.0
SHD1_k127_2183699_30 Tfp pilus assembly protein FimT - - - 0.00000000000114 74.0
SHD1_k127_2183699_31 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000008735 54.0
SHD1_k127_2183699_4 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 604.0
SHD1_k127_2183699_5 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 582.0
SHD1_k127_2183699_6 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 588.0
SHD1_k127_2183699_7 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 553.0
SHD1_k127_2183699_8 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 554.0
SHD1_k127_2183699_9 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 496.0
SHD1_k127_2188521_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 595.0
SHD1_k127_2188521_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001711 231.0
SHD1_k127_2188521_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000002645 214.0
SHD1_k127_2188521_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000001091 197.0
SHD1_k127_2188521_4 Glucose inhibited division protein A K21401 - 1.3.99.38 0.000000000000000000000000000000000316 136.0
SHD1_k127_2191094_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000009008 215.0
SHD1_k127_2191094_1 regulation of response to stimulus - - - 0.00000000000000000000008651 109.0
SHD1_k127_2211795_0 PglZ domain - - - 2.833e-263 819.0
SHD1_k127_2211795_1 ABC transporter transmembrane region K11085 - - 2.256e-221 705.0
SHD1_k127_2211795_2 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 405.0
SHD1_k127_2211795_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 327.0
SHD1_k127_2211795_4 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 332.0
SHD1_k127_2211795_5 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000007443 246.0
SHD1_k127_2214019_0 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000301 272.0
SHD1_k127_2214019_1 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000348 202.0
SHD1_k127_2222612_1 Flp Fap pilin component K02651 - - 0.000000002799 60.0
SHD1_k127_2234681_0 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000197 166.0
SHD1_k127_2234681_1 Ribosomal L27 protein K02899 - - 0.000000000000000000000000000000000000002013 148.0
SHD1_k127_2234681_2 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000002464 114.0
SHD1_k127_2240728_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 392.0
SHD1_k127_2240728_1 Part of the ABC transporter FtsEX involved in K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 315.0
SHD1_k127_2240728_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 287.0
SHD1_k127_2240728_3 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005064 278.0
SHD1_k127_2240728_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000007955 196.0
SHD1_k127_2243689_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 1.226e-226 707.0
SHD1_k127_2243689_1 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 421.0
SHD1_k127_2243689_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 372.0
SHD1_k127_2243689_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 314.0
SHD1_k127_2243689_4 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000002734 209.0
SHD1_k127_2243689_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000003767 173.0
SHD1_k127_2243689_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000001294 109.0
SHD1_k127_2244354_0 Amidohydrolase family K06015 - 3.5.1.81 5.454e-213 676.0
SHD1_k127_2244354_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 576.0
SHD1_k127_2244354_10 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000001024 238.0
SHD1_k127_2244354_11 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000007593 222.0
SHD1_k127_2244354_12 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000004246 223.0
SHD1_k127_2244354_13 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000005547 218.0
SHD1_k127_2244354_14 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000006113 201.0
SHD1_k127_2244354_15 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000001214 200.0
SHD1_k127_2244354_16 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000001696 194.0
SHD1_k127_2244354_17 Cupin domain - - - 0.0000000000000000000000000000000000000000000000003762 181.0
SHD1_k127_2244354_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000001098 198.0
SHD1_k127_2244354_19 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000769 162.0
SHD1_k127_2244354_2 biosynthesis protein E K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 435.0
SHD1_k127_2244354_20 PFAM Ferritin Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000002672 154.0
SHD1_k127_2244354_21 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000001431 142.0
SHD1_k127_2244354_22 Histidine kinase - - - 0.0000000000000000000000000000000004791 151.0
SHD1_k127_2244354_23 DinB family - - - 0.0000000000000000000000000000000005835 138.0
SHD1_k127_2244354_24 COG3668 Plasmid stabilization system protein - - - 0.000000000000000000000000000000001131 134.0
SHD1_k127_2244354_25 DinB family - - - 0.0000000000000000000000000000003912 129.0
SHD1_k127_2244354_26 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000001242 102.0
SHD1_k127_2244354_27 pyrroloquinoline quinone biosynthesis protein D K06138 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000007085 84.0
SHD1_k127_2244354_29 - - - - 0.0000000003557 68.0
SHD1_k127_2244354_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 364.0
SHD1_k127_2244354_30 - - - - 0.0000007958 57.0
SHD1_k127_2244354_32 - - - - 0.00002599 49.0
SHD1_k127_2244354_33 - - - - 0.0002024 51.0
SHD1_k127_2244354_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 364.0
SHD1_k127_2244354_5 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 316.0
SHD1_k127_2244354_6 uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 267.0
SHD1_k127_2244354_7 Domain of unknown function (DUF1949) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001902 245.0
SHD1_k127_2244354_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000002486 237.0
SHD1_k127_2244354_9 methionine sulfoxide reductase K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000006389 232.0
SHD1_k127_2254743_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 4.034e-209 655.0
SHD1_k127_2254743_1 PFAM YCII-related - - - 0.0000000000000000000000000000000000000000000000000000003376 198.0
SHD1_k127_2254743_2 Protein of unknown function (DUF1097) - - - 0.000000000000000000000000000000000000000000000002759 178.0
SHD1_k127_2254743_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000475 132.0
SHD1_k127_2254743_4 - - - - 0.00000000000000000000000000000004893 134.0
SHD1_k127_2263396_0 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000002533 186.0
SHD1_k127_2263396_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000002454 148.0
SHD1_k127_2267705_0 Aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 524.0
SHD1_k127_2267707_0 Tricorn protease homolog - - - 4.003e-277 878.0
SHD1_k127_2267707_1 Sugar (and other) transporter K03446 - - 3.738e-244 764.0
SHD1_k127_2267707_2 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
SHD1_k127_2267707_3 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005611 259.0
SHD1_k127_2267707_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001115 196.0
SHD1_k127_2267707_5 DoxX-like family - - - 0.000000000003383 78.0
SHD1_k127_2267707_6 Copper binding proteins, plastocyanin/azurin family - - - 0.00001543 53.0
SHD1_k127_2267707_7 Bacterial Ig-like domain 2 - - - 0.00001575 55.0
SHD1_k127_2271731_0 Major facilitator Superfamily K08178 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 554.0
SHD1_k127_2271731_1 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 467.0
SHD1_k127_2271731_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000725 192.0
SHD1_k127_2271731_11 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000005328 180.0
SHD1_k127_2271731_12 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000006108 170.0
SHD1_k127_2271731_13 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000008648 131.0
SHD1_k127_2271731_14 nuclear chromosome segregation - - - 0.000000000000000000000000000145 127.0
SHD1_k127_2271731_15 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.00000000000000000000000001963 110.0
SHD1_k127_2271731_16 - - - - 0.0000000000000000169 87.0
SHD1_k127_2271731_17 - - - - 0.000000000000005392 85.0
SHD1_k127_2271731_18 Bacterial Ig-like domain 2 - - - 0.00000003849 66.0
SHD1_k127_2271731_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 434.0
SHD1_k127_2271731_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 417.0
SHD1_k127_2271731_4 PFAM short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 398.0
SHD1_k127_2271731_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 343.0
SHD1_k127_2271731_6 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 326.0
SHD1_k127_2271731_7 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 300.0
SHD1_k127_2271731_8 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002506 252.0
SHD1_k127_2271731_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000003249 232.0
SHD1_k127_2298200_0 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 350.0
SHD1_k127_2298200_1 homoserine kinase activity K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000001311 249.0
SHD1_k127_2298200_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000001447 221.0
SHD1_k127_2298200_3 cyclic nucleotide binding K07001,K10914 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000003141 203.0
SHD1_k127_2298200_4 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000001184 201.0
SHD1_k127_2298200_5 - - - - 0.00000000000000000000000000000000000000000002548 168.0
SHD1_k127_2298200_6 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000002539 128.0
SHD1_k127_2298200_7 - - - - 0.0000000000000000000000004714 116.0
SHD1_k127_2298200_8 Domains FehydlgC, FeS, sigma54 interaction, HTH8 - - - 0.00000003244 66.0
SHD1_k127_2298200_9 Outer membrane protein beta-barrel domain - - - 0.000267 45.0
SHD1_k127_2306358_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 507.0
SHD1_k127_2306358_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 464.0
SHD1_k127_2306358_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 291.0
SHD1_k127_2306358_3 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000003512 161.0
SHD1_k127_2306358_4 DinB superfamily - - - 0.00000000000000000000000000000000000000002483 158.0
SHD1_k127_2306358_5 Ferredoxin - - - 0.00000000000000000003473 93.0
SHD1_k127_2306358_6 Transcriptional regulator K07979 - - 0.0007801 47.0
SHD1_k127_231441_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 359.0
SHD1_k127_231441_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001731 201.0
SHD1_k127_2317927_0 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000000000953 129.0
SHD1_k127_2317927_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000685 121.0
SHD1_k127_2317927_2 - - - - 0.0000001827 59.0
SHD1_k127_2317927_3 - - - - 0.00002514 51.0
SHD1_k127_2319471_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.463e-234 735.0
SHD1_k127_2319471_1 B3/4 domain K01890 - 6.1.1.20 1.688e-234 756.0
SHD1_k127_2319471_10 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000002551 106.0
SHD1_k127_2319471_11 Ribosomal protein L35 K02916 - - 0.00000000000000000003827 91.0
SHD1_k127_2319471_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 441.0
SHD1_k127_2319471_3 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 405.0
SHD1_k127_2319471_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 370.0
SHD1_k127_2319471_5 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 299.0
SHD1_k127_2319471_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007589 277.0
SHD1_k127_2319471_7 Arginine deiminase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001134 275.0
SHD1_k127_2319471_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000002904 187.0
SHD1_k127_2319471_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000005414 166.0
SHD1_k127_2334732_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000006166 217.0
SHD1_k127_2341308_0 Belongs to the glycosyl hydrolase 43 family - - - 4.431e-271 845.0
SHD1_k127_2341308_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 326.0
SHD1_k127_2345989_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.235e-222 700.0
SHD1_k127_2345989_1 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 569.0
SHD1_k127_2345989_2 protein deglycation K18199 - 4.2.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 311.0
SHD1_k127_2345989_3 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 295.0
SHD1_k127_2345989_4 Dihydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001728 240.0
SHD1_k127_2345989_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001832 191.0
SHD1_k127_2345989_6 - - - - 0.000000000000000000000000000000000000001903 153.0
SHD1_k127_2345989_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000002972 141.0
SHD1_k127_2345989_8 ACT domain K09707 - - 0.00000000000000000000000000001731 122.0
SHD1_k127_2353016_0 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 5.136e-196 617.0
SHD1_k127_2353016_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 482.0
SHD1_k127_2353016_2 GIY-YIG type nucleases (URI domain) K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 422.0
SHD1_k127_2353016_3 Belongs to the GARS family K01945,K11788 - 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 407.0
SHD1_k127_2353016_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 381.0
SHD1_k127_2353016_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 379.0
SHD1_k127_2353016_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 316.0
SHD1_k127_2353016_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003702 291.0
SHD1_k127_2353016_8 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000009719 199.0
SHD1_k127_2365708_0 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 470.0
SHD1_k127_2365708_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 455.0
SHD1_k127_2365708_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 267.0
SHD1_k127_2365708_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004126 244.0
SHD1_k127_2365708_4 Belongs to the bacterial solute-binding protein 9 family - - - 0.000000000000000000000000000000000002341 158.0
SHD1_k127_2366816_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.091e-285 882.0
SHD1_k127_2366816_1 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
SHD1_k127_2366816_2 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 380.0
SHD1_k127_2366816_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 328.0
SHD1_k127_2366816_4 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000003402 216.0
SHD1_k127_2366816_5 ABC transporter K06861 - - 0.00000000000000000001009 98.0
SHD1_k127_2388356_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 526.0
SHD1_k127_2388356_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001659 201.0
SHD1_k127_2394283_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 599.0
SHD1_k127_2397135_0 RecQ zinc-binding K03654 - 3.6.4.12 4.767e-233 737.0
SHD1_k127_2409828_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 598.0
SHD1_k127_2409828_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 431.0
SHD1_k127_2409828_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 346.0
SHD1_k127_2409828_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000002258 240.0
SHD1_k127_2409828_4 Glycine D-amino acid oxidase (deaminating) - - - 0.00000000000000000000000006052 109.0
SHD1_k127_2409828_5 Glycosyl transferase K13668 - 2.4.1.346 0.0000000000000000004558 94.0
SHD1_k127_2409828_6 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000375 75.0
SHD1_k127_2409828_7 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K05785 - - 0.00000007623 61.0
SHD1_k127_2409828_8 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000002143 58.0
SHD1_k127_2422351_0 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 575.0
SHD1_k127_2422351_1 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003122 287.0
SHD1_k127_2438788_0 Helix-hairpin-helix motif K14162 - 2.7.7.7 0.0 1321.0
SHD1_k127_2438788_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 408.0
SHD1_k127_2438788_2 methylisocitrate lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001331 233.0
SHD1_k127_2438788_3 Rad51 - - - 0.0000000000000000000000000000000000000001809 162.0
SHD1_k127_2440611_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 424.0
SHD1_k127_2440611_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 421.0
SHD1_k127_2440611_2 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 299.0
SHD1_k127_2440611_3 Part of the ABC transporter FtsEX involved in K09811 - - 0.0000000000000000000000000000000000000000000000000001894 192.0
SHD1_k127_2440611_4 - - - - 0.00000000000000000000000000000000000000000000001359 188.0
SHD1_k127_2440611_5 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000001103 159.0
SHD1_k127_2440611_6 - - - - 0.0000000000000000000004098 103.0
SHD1_k127_2445064_0 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 590.0
SHD1_k127_2445064_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 459.0
SHD1_k127_2445064_2 Glycosyl hydrolase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 407.0
SHD1_k127_2445064_3 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000001829 221.0
SHD1_k127_2445064_4 Glycosyl hydrolase family 1 K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000003665 184.0
SHD1_k127_2450059_0 efflux transmembrane transporter activity - - - 1.032e-206 659.0
SHD1_k127_2450059_1 DinB superfamily - - - 0.000000000000000000000000000000000000002552 151.0
SHD1_k127_2450059_2 - - - - 0.00001542 50.0
SHD1_k127_2459720_0 DALR_2 K01883 - 6.1.1.16 2.652e-219 689.0
SHD1_k127_2459720_1 - - - - 0.00000000000000000001543 94.0
SHD1_k127_2459720_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000003303 78.0
SHD1_k127_2459720_3 ABC transporter K02003 - - 0.0000003846 60.0
SHD1_k127_2459720_4 - - - - 0.0002677 44.0
SHD1_k127_2461871_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 1.847e-222 713.0
SHD1_k127_2461871_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000009578 141.0
SHD1_k127_2461871_2 MacB-like periplasmic core domain - - - 0.0000000000000000002645 96.0
SHD1_k127_2462639_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 611.0
SHD1_k127_2462639_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 310.0
SHD1_k127_2462639_10 Tetratricopeptide repeat K07114 - - 0.000000000006312 75.0
SHD1_k127_2462639_11 lysyltransferase activity - - - 0.00000000001384 76.0
SHD1_k127_2462639_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000007722 246.0
SHD1_k127_2462639_3 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000004122 243.0
SHD1_k127_2462639_4 Protein of unknown function (DUF1698) - - - 0.0000000000000000000000000000000000000000000000000000000000002174 224.0
SHD1_k127_2462639_5 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000006003 201.0
SHD1_k127_2462639_6 - - - - 0.00000000000000000000000000000000000000000000000000001466 198.0
SHD1_k127_2462639_7 - - - - 0.0000000000000000000000000000000000000000000001573 177.0
SHD1_k127_2462639_8 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000158 132.0
SHD1_k127_2462639_9 Transglycosylase associated protein - - - 0.00000000000000000000000000002275 121.0
SHD1_k127_2465233_0 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 3.284e-306 966.0
SHD1_k127_2465233_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
SHD1_k127_2465800_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000004986 188.0
SHD1_k127_2465800_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000008118 168.0
SHD1_k127_2465800_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000161 164.0
SHD1_k127_2465800_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000008231 156.0
SHD1_k127_249044_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 552.0
SHD1_k127_249044_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 526.0
SHD1_k127_249044_10 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000137 126.0
SHD1_k127_249044_11 - - - - 0.000000000000000000000001092 120.0
SHD1_k127_249044_2 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 463.0
SHD1_k127_249044_3 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 404.0
SHD1_k127_249044_4 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 397.0
SHD1_k127_249044_5 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 336.0
SHD1_k127_249044_6 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000339 270.0
SHD1_k127_249044_7 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008166 266.0
SHD1_k127_249044_8 nUDIX hydrolase K01515,K03574,K08310 - 3.6.1.13,3.6.1.55,3.6.1.67 0.00000000000000000000000000000000000000000000000000000000007049 209.0
SHD1_k127_249044_9 - - - - 0.000000000000000000000000000000000000000000000000000000001655 216.0
SHD1_k127_2495981_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 583.0
SHD1_k127_2495981_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 542.0
SHD1_k127_2495981_2 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 513.0
SHD1_k127_2495981_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 391.0
SHD1_k127_249692_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 6.528e-232 722.0
SHD1_k127_249692_1 E1-E2 ATPase K17686 - 3.6.3.54 2.981e-231 733.0
SHD1_k127_249692_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 509.0
SHD1_k127_249692_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003073 275.0
SHD1_k127_249692_4 Ndr family - - - 0.00000000000000000000000000000000000000002574 164.0
SHD1_k127_249692_5 mercury ion transmembrane transporter activity K07213 - - 0.00000000001179 68.0
SHD1_k127_2519110_0 Peptidase family M1 domain - - - 8.316e-245 767.0
SHD1_k127_2519110_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000005439 212.0
SHD1_k127_2519110_2 Protein of unknown function (DUF2911) - - - 0.00000000000000000000003284 108.0
SHD1_k127_2520745_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 593.0
SHD1_k127_2520745_1 purine ribonucleoside salvage K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000008767 265.0
SHD1_k127_2520745_2 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000002567 217.0
SHD1_k127_2520745_3 - - - - 0.00000000000000000000000000000000000000000000000000000000985 212.0
SHD1_k127_2520745_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000002341 181.0
SHD1_k127_2520745_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000001039 156.0
SHD1_k127_2520745_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000002136 154.0
SHD1_k127_2520745_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000001452 110.0
SHD1_k127_2520745_8 Protein of unknown function (DUF3761) - - - 0.0000002026 59.0
SHD1_k127_252370_0 FAD binding domain K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 398.0
SHD1_k127_252370_1 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.000000000000000000000000000000000000000000000000000007113 205.0
SHD1_k127_252370_2 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000001605 130.0
SHD1_k127_252370_3 SCO1 SenC K07152 - - 0.0000000000000000000000001525 110.0
SHD1_k127_252370_4 - - - - 0.0000000004143 63.0
SHD1_k127_2529509_0 peptide catabolic process K01992 - - 0.0 1724.0
SHD1_k127_2529509_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 486.0
SHD1_k127_2530615_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.782e-293 908.0
SHD1_k127_2530615_1 Aromatic amino acid lyase K01745 - 4.3.1.3 6.017e-212 669.0
SHD1_k127_2530615_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000679 108.0
SHD1_k127_2561156_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000002044 124.0
SHD1_k127_2561156_1 Phosphoglycerate mutase family K08296 - - 0.000003396 49.0
SHD1_k127_2563562_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007538 281.0
SHD1_k127_2563562_1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000004435 127.0
SHD1_k127_2563562_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000001843 68.0
SHD1_k127_2573581_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 439.0
SHD1_k127_2573581_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 393.0
SHD1_k127_2573581_2 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 368.0
SHD1_k127_2573581_3 ATPase-coupled sulfate transmembrane transporter activity K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 293.0
SHD1_k127_2573581_4 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006457 237.0
SHD1_k127_2573581_5 Disulphide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000344 206.0
SHD1_k127_2573581_6 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000002137 208.0
SHD1_k127_2573581_7 Belongs to the ABC transporter superfamily K02017,K02045,K15497 - 3.6.3.25,3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000001555 193.0
SHD1_k127_2573581_8 - - - - 0.000000000001246 76.0
SHD1_k127_2588851_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.204e-304 942.0
SHD1_k127_2588851_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 1.147e-198 628.0
SHD1_k127_2588851_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001318 304.0
SHD1_k127_2588851_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004759 272.0
SHD1_k127_2588851_4 SMART chemotaxis sensory transducer, histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000001043 186.0
SHD1_k127_2594295_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 568.0
SHD1_k127_2595086_0 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000378 248.0
SHD1_k127_2595086_1 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.0000000000000000000000000000000000004239 142.0
SHD1_k127_2595086_2 - - - - 0.00002338 53.0
SHD1_k127_2597110_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 369.0
SHD1_k127_2597110_1 Domain of unknown function (DUF4184) - - - 0.0000000000000000001622 98.0
SHD1_k127_2597110_2 PFAM acyltransferase 3 - - - 0.000000000000000075 84.0
SHD1_k127_2597110_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000002319 90.0
SHD1_k127_2602766_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 558.0
SHD1_k127_2602766_1 UDP binding domain K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 438.0
SHD1_k127_2602766_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000003152 195.0
SHD1_k127_2602766_3 Late embryogenesis abundant protein - - - 0.000000000000000000000000000000000000000000007506 168.0
SHD1_k127_2602766_4 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000953 101.0
SHD1_k127_2620156_0 4Fe-4S dicluster domain - - - 1.633e-272 854.0
SHD1_k127_2620156_1 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 404.0
SHD1_k127_2620156_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 396.0
SHD1_k127_2620156_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000001236 218.0
SHD1_k127_2621861_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1052.0
SHD1_k127_2621861_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 344.0
SHD1_k127_2621861_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000008135 205.0
SHD1_k127_2621861_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000002863 115.0
SHD1_k127_2663172_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 445.0
SHD1_k127_2663172_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 420.0
SHD1_k127_2663172_2 Phospholipase - - - 0.0000000000000000001935 103.0
SHD1_k127_2663172_3 Peptidase family M1 domain - - - 0.000000000000000005052 86.0
SHD1_k127_2670672_0 Dehydrogenase - - - 2.537e-220 694.0
SHD1_k127_2670672_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 353.0
SHD1_k127_2670672_2 PFAM RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 302.0
SHD1_k127_2670672_3 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000006076 110.0
SHD1_k127_2678777_0 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 276.0
SHD1_k127_2678777_1 metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002695 281.0
SHD1_k127_2678777_2 Acetyltransferase (GNAT) domain - - - 0.00000000000716 72.0
SHD1_k127_2681426_0 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 481.0
SHD1_k127_2681426_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 422.0
SHD1_k127_2681426_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 300.0
SHD1_k127_2681426_3 epoxide hydrolase - - - 0.000000001966 58.0
SHD1_k127_2684710_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 392.0
SHD1_k127_2684710_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 308.0
SHD1_k127_2684710_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 306.0
SHD1_k127_2684710_3 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000002877 187.0
SHD1_k127_2684710_4 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000001699 85.0
SHD1_k127_268775_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1030.0
SHD1_k127_268775_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001278 242.0
SHD1_k127_268775_2 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000001272 217.0
SHD1_k127_268775_3 - - - - 0.0000000000000000000000000000000000000000001649 163.0
SHD1_k127_268775_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000003878 102.0
SHD1_k127_268775_5 quinone binding - - - 0.000000000000001341 83.0
SHD1_k127_268775_6 ABC transporter K02193 - 3.6.3.41 0.000000000000003182 80.0
SHD1_k127_2708095_0 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 454.0
SHD1_k127_2708095_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 307.0
SHD1_k127_2708095_2 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000578 90.0
SHD1_k127_2710802_0 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 593.0
SHD1_k127_2710802_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 471.0
SHD1_k127_2710802_2 Transcriptional regulator K07979 - - 0.00000000000000000000000000000000000000000000001745 184.0
SHD1_k127_2711975_0 DbpA RNA binding domain K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 333.0
SHD1_k127_2711975_1 Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 293.0
SHD1_k127_2711975_2 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 299.0
SHD1_k127_2711975_3 COGs COG2380 conserved - - - 0.0000000000000000000000000004573 122.0
SHD1_k127_2711975_4 - - - - 0.0000000000000000001743 103.0
SHD1_k127_2711975_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000002484 78.0
SHD1_k127_271628_0 C-terminus of AA_permease K03294 - - 1.1e-211 669.0
SHD1_k127_271628_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 396.0
SHD1_k127_271628_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001542 274.0
SHD1_k127_271628_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002674 231.0
SHD1_k127_271628_4 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000001129 148.0
SHD1_k127_271628_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002653 60.0
SHD1_k127_2719859_0 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 359.0
SHD1_k127_2719859_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000008453 126.0
SHD1_k127_2719859_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.00000000000000000000000000137 121.0
SHD1_k127_2727139_0 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 589.0
SHD1_k127_2727139_1 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.00000000000000000000000000000000000000000000000000005241 197.0
SHD1_k127_2727139_2 Prokaryotic homologs of the JAB domain K11864 - - 0.000058 55.0
SHD1_k127_2729675_0 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000002546 169.0
SHD1_k127_2729675_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000002309 149.0
SHD1_k127_2729675_2 SnoaL-like domain - - - 0.0000004926 57.0
SHD1_k127_2731343_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 462.0
SHD1_k127_2731343_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000002064 123.0
SHD1_k127_2771156_0 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 539.0
SHD1_k127_2781533_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 396.0
SHD1_k127_2781533_1 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000004679 204.0
SHD1_k127_2781533_2 - - - - 0.00000000000000000000000000000000000007775 159.0
SHD1_k127_2781533_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000002833 144.0
SHD1_k127_2786716_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1251.0
SHD1_k127_2786716_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 9.271e-226 706.0
SHD1_k127_2786716_2 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 328.0
SHD1_k127_2786716_3 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 287.0
SHD1_k127_2786716_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000269 207.0
SHD1_k127_2786716_5 Histidine kinase - - - 0.00000000000000000000000000000000000003515 161.0
SHD1_k127_2786716_6 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000001625 103.0
SHD1_k127_2800072_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005087 226.0
SHD1_k127_2800072_1 MAPEG family - - - 0.00000000000000000000000000000000000000001806 156.0
SHD1_k127_2811385_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 465.0
SHD1_k127_2811385_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 434.0
SHD1_k127_2811385_10 Recombinase zinc beta ribbon domain - - - 0.000007896 51.0
SHD1_k127_2811385_2 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 400.0
SHD1_k127_2811385_3 Domain of unknown function (DUF3471) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 369.0
SHD1_k127_2811385_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 293.0
SHD1_k127_2811385_5 - - - - 0.0000000000000000000000000000000000000008622 160.0
SHD1_k127_2811385_6 Thioesterase superfamily - - - 0.000000000000000000000000000000004211 141.0
SHD1_k127_2811385_7 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000009724 121.0
SHD1_k127_2811385_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000007628 77.0
SHD1_k127_2815131_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 544.0
SHD1_k127_2815131_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000009821 183.0
SHD1_k127_2815131_2 dksA traR - - - 0.000000000000000000001893 102.0
SHD1_k127_2816588_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 505.0
SHD1_k127_2816588_1 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000001885 185.0
SHD1_k127_2816588_2 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000002136 171.0
SHD1_k127_2816588_3 Redoxin - - - 0.000000000000000000000000000000000000001446 154.0
SHD1_k127_2846375_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 4.495e-240 749.0
SHD1_k127_2846375_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 310.0
SHD1_k127_2846375_3 Cytidylate kinase-like family - - - 0.000000000000000001158 95.0
SHD1_k127_2854705_0 MacB-like periplasmic core domain - - - 7.717e-209 679.0
SHD1_k127_2854705_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 550.0
SHD1_k127_2854705_2 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004851 262.0
SHD1_k127_2854705_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001592 222.0
SHD1_k127_2854705_4 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000002197 193.0
SHD1_k127_2854705_5 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000006979 124.0
SHD1_k127_2854705_6 Cytochrome c - - - 0.00000000000000000000000000008382 118.0
SHD1_k127_2854705_7 DNA-binding transcription factor activity - - - 0.000000000000000000000000001151 115.0
SHD1_k127_2854705_8 Curli production assembly/transport component CsgG - - - 0.0000009041 59.0
SHD1_k127_2864247_0 HELICc2 K03722 - 3.6.4.12 0.0 1092.0
SHD1_k127_2864247_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 7.385e-195 623.0
SHD1_k127_2864247_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 586.0
SHD1_k127_2864247_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 430.0
SHD1_k127_2864247_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 297.0
SHD1_k127_2864247_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000005524 227.0
SHD1_k127_2864247_6 secondary active sulfate transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000002213 183.0
SHD1_k127_2864247_7 - - - - 0.0000000000000000000000000000000006357 145.0
SHD1_k127_2874978_0 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 383.0
SHD1_k127_2874978_1 PFAM Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009396 326.0
SHD1_k127_2881092_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 553.0
SHD1_k127_2881092_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 501.0
SHD1_k127_2881092_2 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 364.0
SHD1_k127_2881092_3 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 327.0
SHD1_k127_2881092_4 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 346.0
SHD1_k127_2881092_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003081 266.0
SHD1_k127_2881092_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.00000000000000000000133 96.0
SHD1_k127_2881092_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000003164 61.0
SHD1_k127_2881520_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 476.0
SHD1_k127_2881520_1 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 364.0
SHD1_k127_2881520_2 Evidence 4 Homologs of previously reported genes of - - - 0.00055 46.0
SHD1_k127_2894739_0 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 421.0
SHD1_k127_2894739_1 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 378.0
SHD1_k127_2894739_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 357.0
SHD1_k127_2894739_3 S4 domain protein - - - 0.00000000000006255 74.0
SHD1_k127_2894739_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0006879 45.0
SHD1_k127_2895770_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 625.0
SHD1_k127_2895770_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 345.0
SHD1_k127_2895770_2 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000003454 201.0
SHD1_k127_2905946_0 Amidohydrolase family - - - 2.598e-218 696.0
SHD1_k127_2905946_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 488.0
SHD1_k127_2905946_2 Belongs to the thiolase family K00626,K07823 - 2.3.1.174,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 456.0
SHD1_k127_2905946_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000005046 210.0
SHD1_k127_2905946_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000001459 179.0
SHD1_k127_2919172_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 9.77e-230 721.0
SHD1_k127_2919172_1 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 323.0
SHD1_k127_2919172_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 295.0
SHD1_k127_2919172_3 - - - - 0.0000000000000000000000000000000000000000000000000000001434 201.0
SHD1_k127_2919172_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000003497 209.0
SHD1_k127_2919172_5 - - - - 0.00000000000000000000000000000000000000000000000004308 188.0
SHD1_k127_2919172_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000002843 153.0
SHD1_k127_2919172_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000003447 151.0
SHD1_k127_2919172_9 - - - - 0.0006651 43.0
SHD1_k127_2919845_0 Amidohydrolase family - - - 9.232e-218 696.0
SHD1_k127_2919845_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000006008 128.0
SHD1_k127_2919845_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000008538 130.0
SHD1_k127_2920048_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 547.0
SHD1_k127_2920048_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 383.0
SHD1_k127_2920048_2 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 360.0
SHD1_k127_2920048_3 protein kinase activity - - - 0.00000000000000000002456 106.0
SHD1_k127_2920048_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0001978 49.0
SHD1_k127_2928266_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 495.0
SHD1_k127_2928266_1 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003544 264.0
SHD1_k127_2928266_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000001978 198.0
SHD1_k127_2928266_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000001132 60.0
SHD1_k127_2942825_0 Formate dehydrogenase alpha subunit K00123,K05299 - 1.17.1.10,1.17.1.9 1.171e-242 783.0
SHD1_k127_2942825_1 Putative modulator of DNA gyrase K03568 - - 2.718e-235 736.0
SHD1_k127_2942825_2 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 550.0
SHD1_k127_2942825_3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000001659 212.0
SHD1_k127_2965143_0 - - - - 0.0000000000000000000000000000000000000000000000000167 187.0
SHD1_k127_2965143_1 transport system, permease component K01992 - - 0.000000000000005915 77.0
SHD1_k127_2965143_2 - - - - 0.00000000000003118 83.0
SHD1_k127_2965143_3 TonB dependent receptor K02014 - - 0.00000000000005617 77.0
SHD1_k127_2965143_4 Domain of unknown function (DUF4412) - - - 0.000000001998 67.0
SHD1_k127_2965206_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 497.0
SHD1_k127_2965206_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 475.0
SHD1_k127_2965206_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001054 279.0
SHD1_k127_2965206_3 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000008118 201.0
SHD1_k127_2965206_4 ketosteroid isomerase - - - 0.000006093 48.0
SHD1_k127_2971515_0 Collagenase K08303 - - 0.0 1074.0
SHD1_k127_2971515_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 380.0
SHD1_k127_3007329_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 330.0
SHD1_k127_3007329_1 Cysteine-rich CPXCG - - - 0.0000000000000000000000005479 109.0
SHD1_k127_3007329_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000001395 100.0
SHD1_k127_3013532_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 4.349e-257 801.0
SHD1_k127_3013532_1 sirohydrochlorin cobaltochelatase activity K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.00000000000000000002514 96.0
SHD1_k127_3017006_0 FAD dependent oxidoreductase - - - 8.129e-236 739.0
SHD1_k127_3017006_1 domain protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 563.0
SHD1_k127_3017006_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 343.0
SHD1_k127_3017006_11 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 305.0
SHD1_k127_3017006_12 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 265.0
SHD1_k127_3017006_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000003549 274.0
SHD1_k127_3017006_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 258.0
SHD1_k127_3017006_15 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000006867 206.0
SHD1_k127_3017006_16 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000919 176.0
SHD1_k127_3017006_17 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000001109 137.0
SHD1_k127_3017006_18 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000009596 107.0
SHD1_k127_3017006_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 565.0
SHD1_k127_3017006_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 474.0
SHD1_k127_3017006_4 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 448.0
SHD1_k127_3017006_5 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 438.0
SHD1_k127_3017006_6 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 434.0
SHD1_k127_3017006_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 443.0
SHD1_k127_3017006_8 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 383.0
SHD1_k127_3017006_9 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 378.0
SHD1_k127_3018305_0 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 378.0
SHD1_k127_3018305_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 339.0
SHD1_k127_3044655_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.694e-283 884.0
SHD1_k127_3044655_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 2.211e-210 668.0
SHD1_k127_3044655_10 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001765 272.0
SHD1_k127_3044655_11 Glycosyl transferase family 2 K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005686 274.0
SHD1_k127_3044655_12 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006151 266.0
SHD1_k127_3044655_13 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000004102 257.0
SHD1_k127_3044655_14 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000168 223.0
SHD1_k127_3044655_15 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000002867 197.0
SHD1_k127_3044655_16 - - - - 0.000000000000000001038 88.0
SHD1_k127_3044655_17 - - - - 0.000000000000009139 81.0
SHD1_k127_3044655_2 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 567.0
SHD1_k127_3044655_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 502.0
SHD1_k127_3044655_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 492.0
SHD1_k127_3044655_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 446.0
SHD1_k127_3044655_6 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 349.0
SHD1_k127_3044655_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 345.0
SHD1_k127_3044655_8 domain, Protein K01179,K07260,K13735 - 3.2.1.4,3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 323.0
SHD1_k127_3044655_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 302.0
SHD1_k127_3054255_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2470.0
SHD1_k127_3054255_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 372.0
SHD1_k127_3054255_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 330.0
SHD1_k127_3054255_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 295.0
SHD1_k127_3054255_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009449 245.0
SHD1_k127_3054255_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000007169 214.0
SHD1_k127_3054255_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000009875 191.0
SHD1_k127_3054255_7 Ribosomal protein L33 K02913 - - 0.00000000000000000000000995 100.0
SHD1_k127_3054255_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000004514 51.0
SHD1_k127_3067486_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 470.0
SHD1_k127_3067486_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000001049 118.0
SHD1_k127_3067486_2 - - - - 0.000000000000004506 84.0
SHD1_k127_3067486_3 Transglutaminase-like superfamily - - - 0.00000284 54.0
SHD1_k127_3069760_0 Transport of potassium into the cell K03549 - - 1.252e-253 797.0
SHD1_k127_3069760_1 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 8.487e-212 665.0
SHD1_k127_3069760_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 502.0
SHD1_k127_3069760_3 cellular manganese ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 373.0
SHD1_k127_3069760_4 Putative MetA-pathway of phenol degradation - - - 0.00000002276 66.0
SHD1_k127_307215_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1479.0
SHD1_k127_307215_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 496.0
SHD1_k127_307215_2 PFAM Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 493.0
SHD1_k127_307215_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000546 48.0
SHD1_k127_307215_4 - - - - 0.000006772 52.0
SHD1_k127_3089303_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 1.039e-266 844.0
SHD1_k127_3089303_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 2.707e-261 823.0
SHD1_k127_3089303_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 462.0
SHD1_k127_3089303_3 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000004161 174.0
SHD1_k127_3089303_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000001632 119.0
SHD1_k127_3089303_5 Selenoprotein, putative - - - 0.0000000000004056 73.0
SHD1_k127_3099627_0 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 343.0
SHD1_k127_3099627_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008442 268.0
SHD1_k127_3099627_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000006655 158.0
SHD1_k127_3099627_3 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000434 150.0
SHD1_k127_3105130_0 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 287.0
SHD1_k127_3105130_1 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000001037 218.0
SHD1_k127_3105130_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000001835 181.0
SHD1_k127_3111342_0 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 431.0
SHD1_k127_3111342_1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 315.0
SHD1_k127_3111342_2 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003233 259.0
SHD1_k127_3111342_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000001919 51.0
SHD1_k127_3117585_0 2-dehydropantoate 2-reductase activity K00077,K01295 - 1.1.1.169,3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 413.0
SHD1_k127_3117585_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 370.0
SHD1_k127_3117585_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 356.0
SHD1_k127_3117585_3 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 343.0
SHD1_k127_3117585_4 Peptidase dimerisation domain protein - - - 0.00000000000000000000000000004849 121.0
SHD1_k127_3117585_5 Hydrolase CocE NonD family K06978 - - 0.00000000000000000000006098 111.0
SHD1_k127_3120723_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 314.0
SHD1_k127_3120723_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000005375 179.0
SHD1_k127_3120723_2 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000002158 126.0
SHD1_k127_3120723_3 - - - - 0.0000000000000000000000004433 115.0
SHD1_k127_3120723_4 Amidohydrolase family - - - 0.00000000000000000007201 95.0
SHD1_k127_3130206_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.342e-311 975.0
SHD1_k127_3130206_1 Surface antigen K07277 - - 5.377e-288 905.0
SHD1_k127_3130206_10 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 314.0
SHD1_k127_3130206_11 UvrB/uvrC motif K19411 - - 0.00000000000000000000000000000000000000000000000000005511 191.0
SHD1_k127_3130206_12 - - - - 0.0000000000000000000000000000000000000000000000000001609 196.0
SHD1_k127_3130206_13 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000005081 131.0
SHD1_k127_3130206_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.964e-222 706.0
SHD1_k127_3130206_3 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 545.0
SHD1_k127_3130206_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 524.0
SHD1_k127_3130206_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 469.0
SHD1_k127_3130206_6 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 466.0
SHD1_k127_3130206_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 340.0
SHD1_k127_3130206_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 345.0
SHD1_k127_3130206_9 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 307.0
SHD1_k127_3137158_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 284.0
SHD1_k127_3137158_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005658 240.0
SHD1_k127_3137158_2 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000004195 215.0
SHD1_k127_3144618_0 Hsp70 protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 521.0
SHD1_k127_3144618_1 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 324.0
SHD1_k127_3144618_2 Protein of unknown function DUF89 K09116 - - 0.0000000003321 64.0
SHD1_k127_3149905_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.533e-270 836.0
SHD1_k127_3149905_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 4.678e-210 666.0
SHD1_k127_3149905_2 Ribosomal protein S2 K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 435.0
SHD1_k127_3149905_3 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 432.0
SHD1_k127_3149905_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003476 243.0
SHD1_k127_3149905_5 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000000000000002411 207.0
SHD1_k127_3149905_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000616 199.0
SHD1_k127_3149905_7 Biotin-requiring enzyme - - - 0.0000000000000000000000000000000000000000001244 173.0
SHD1_k127_3149905_8 Redoxin - - - 0.0000000000000000001598 97.0
SHD1_k127_3161402_0 Serine aminopeptidase, S33 K19707 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 443.0
SHD1_k127_3161402_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000289 262.0
SHD1_k127_3193542_0 Serine Threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000004907 186.0
SHD1_k127_3193542_1 OsmC-like protein - - - 0.00000000000000000000000000000000000000002488 156.0
SHD1_k127_3193542_2 - - - - 0.000000000000000000000003867 110.0
SHD1_k127_3193542_3 - - - - 0.000000005532 59.0
SHD1_k127_3193909_0 MacB-like periplasmic core domain - - - 9.086e-245 791.0
SHD1_k127_3193909_1 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 381.0
SHD1_k127_3193909_2 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000000236 172.0
SHD1_k127_3193909_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000001077 172.0
SHD1_k127_3198428_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 366.0
SHD1_k127_3198428_1 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000008978 119.0
SHD1_k127_3198428_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.00003569 48.0
SHD1_k127_3229173_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 436.0
SHD1_k127_3229173_1 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 329.0
SHD1_k127_3229173_2 Glycine betaine K05845 - - 0.000000000000000000000000000000000000000000000000000000000000003728 228.0
SHD1_k127_3243129_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.881e-254 799.0
SHD1_k127_3243129_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 364.0
SHD1_k127_3257857_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.794e-249 779.0
SHD1_k127_3257857_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 581.0
SHD1_k127_3257857_2 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 562.0
SHD1_k127_3257857_3 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 452.0
SHD1_k127_3257857_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A - - - 0.000000000000000000000000000000000000000000000000009263 188.0
SHD1_k127_3257857_5 Regulatory protein, FmdB family - - - 0.000000000000000003167 90.0
SHD1_k127_3271266_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 553.0
SHD1_k127_3271266_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 353.0
SHD1_k127_3273866_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.276e-243 784.0
SHD1_k127_3273866_1 Sporulation related domain - - - 0.00000000001272 72.0
SHD1_k127_327621_0 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 500.0
SHD1_k127_327621_1 AlkA N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 341.0
SHD1_k127_327621_2 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001165 265.0
SHD1_k127_327621_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001204 231.0
SHD1_k127_327621_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000004281 193.0
SHD1_k127_327621_5 Protein of unknown function (DUF1706) - - - 0.00000000000000000000000000000000000000000000000003261 183.0
SHD1_k127_327621_6 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000000005496 151.0
SHD1_k127_327621_7 - - - - 0.0000000000000000000000000000000000001846 149.0
SHD1_k127_3287380_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 340.0
SHD1_k127_3287380_1 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
SHD1_k127_3287380_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 322.0
SHD1_k127_3287380_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000006171 211.0
SHD1_k127_3287380_4 Ham1 family K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000002349 213.0
SHD1_k127_3287380_5 - - - - 0.0000000000000000000000000000000000000000000000000000004029 201.0
SHD1_k127_3287380_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776,K02428 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 0.0000000000000000000000000000000000000000000000000003695 192.0
SHD1_k127_3287380_7 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000000002884 188.0
SHD1_k127_3287380_8 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000002825 156.0
SHD1_k127_3292120_0 PFAM Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 509.0
SHD1_k127_3292120_1 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 411.0
SHD1_k127_3292120_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 396.0
SHD1_k127_3292120_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000005093 166.0
SHD1_k127_3292120_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000009218 113.0
SHD1_k127_3292120_5 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000136 107.0
SHD1_k127_3299676_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 308.0
SHD1_k127_3299676_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005796 239.0
SHD1_k127_3299676_2 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000000000000000000000000000000487 152.0
SHD1_k127_3299676_3 - - - - 0.0000001659 63.0
SHD1_k127_3302719_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 456.0
SHD1_k127_3302719_1 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 467.0
SHD1_k127_3302719_10 - - - - 0.00000000001254 71.0
SHD1_k127_3302719_11 - - - - 0.0000001406 63.0
SHD1_k127_3302719_2 Putative RNA methylase family UPF0020 K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 380.0
SHD1_k127_3302719_3 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 373.0
SHD1_k127_3302719_4 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000003237 224.0
SHD1_k127_3302719_5 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000008856 207.0
SHD1_k127_3302719_6 Fe-S metabolism associated domain K02426 - - 0.000000000000000000000000000000000000000000000000000000001663 203.0
SHD1_k127_3302719_7 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000001344 182.0
SHD1_k127_3302719_8 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000004482 174.0
SHD1_k127_3302719_9 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000003231 165.0
SHD1_k127_3323187_0 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 379.0
SHD1_k127_3323187_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000004371 248.0
SHD1_k127_3332991_0 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 428.0
SHD1_k127_3332991_1 peroxidase activity K00435 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 295.0
SHD1_k127_3332991_10 Pfam:DUF2029 - - - 0.00000000000000000007701 98.0
SHD1_k127_3332991_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
SHD1_k127_3332991_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004355 283.0
SHD1_k127_3332991_4 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000001363 237.0
SHD1_k127_3332991_5 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000001479 254.0
SHD1_k127_3332991_6 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000007101 201.0
SHD1_k127_3332991_7 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000669 133.0
SHD1_k127_3332991_8 - - - - 0.00000000000000000000000000000004973 126.0
SHD1_k127_3339364_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 1.965e-254 796.0
SHD1_k127_3339364_1 Peptidase dimerisation domain K12941 - - 1.478e-231 738.0
SHD1_k127_3339364_10 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000001931 156.0
SHD1_k127_3339364_11 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000001192 151.0
SHD1_k127_3339364_12 sequence-specific DNA binding - - - 0.00000000000000000000000000000000006515 143.0
SHD1_k127_3339364_13 Transcriptional regulator TetR - - - 0.000000000000000000000000000001554 132.0
SHD1_k127_3339364_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 476.0
SHD1_k127_3339364_3 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 397.0
SHD1_k127_3339364_4 TIGRFAM phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 313.0
SHD1_k127_3339364_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 292.0
SHD1_k127_3339364_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002369 287.0
SHD1_k127_3339364_7 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002528 280.0
SHD1_k127_3339364_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000002528 177.0
SHD1_k127_3344032_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 521.0
SHD1_k127_3344032_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000001045 158.0
SHD1_k127_3344032_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000002956 126.0
SHD1_k127_3351120_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 5.953e-217 679.0
SHD1_k127_3351120_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 367.0
SHD1_k127_3351120_2 PFAM metal-dependent phosphohydrolase, HD sub domain K02030,K06950,K07814,K09749,K16923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002951 279.0
SHD1_k127_3351120_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000001005 199.0
SHD1_k127_3351120_4 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000177 202.0
SHD1_k127_3351120_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000003604 150.0
SHD1_k127_3351120_6 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.0000000000000000000000000000000000000799 145.0
SHD1_k127_3351120_7 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000001984 150.0
SHD1_k127_3351120_8 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000001157 137.0
SHD1_k127_3352951_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 562.0
SHD1_k127_3352951_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 496.0
SHD1_k127_3352951_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004714 280.0
SHD1_k127_3352951_3 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000001877 196.0
SHD1_k127_3352951_4 VanZ like family - - - 0.000000000000009873 80.0
SHD1_k127_3375317_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 606.0
SHD1_k127_3375317_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 286.0
SHD1_k127_3375317_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000007375 225.0
SHD1_k127_3375317_3 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000001996 181.0
SHD1_k127_3375317_5 COG0438 Glycosyltransferase - - - 0.00000000000000000000002998 114.0
SHD1_k127_3393316_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000005919 223.0
SHD1_k127_3393316_1 glyoxalase III activity K00970 - 2.7.7.19 0.0000000000000000000000000000001709 130.0
SHD1_k127_3433649_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 389.0
SHD1_k127_3433649_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000003149 199.0
SHD1_k127_3433649_2 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000001945 176.0
SHD1_k127_3433649_3 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000001974 106.0
SHD1_k127_3445487_0 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 572.0
SHD1_k127_3445487_1 Ornithine cyclodeaminase/mu-crystallin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001783 271.0
SHD1_k127_3445487_2 isomerase activity K07054 - - 0.0000000000000000000000000000000125 130.0
SHD1_k127_3450965_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 556.0
SHD1_k127_3450965_1 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 492.0
SHD1_k127_3450965_2 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000001251 157.0
SHD1_k127_3450965_3 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000002046 154.0
SHD1_k127_3450965_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000003715 160.0
SHD1_k127_345925_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 554.0
SHD1_k127_345925_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 391.0
SHD1_k127_345925_10 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006822 265.0
SHD1_k127_345925_11 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000002161 164.0
SHD1_k127_345925_12 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000004754 65.0
SHD1_k127_345925_13 - - - - 0.0000007642 61.0
SHD1_k127_345925_2 HAMP domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 407.0
SHD1_k127_345925_3 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 387.0
SHD1_k127_345925_4 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 361.0
SHD1_k127_345925_5 Bacterial extracellular solute-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 340.0
SHD1_k127_345925_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 317.0
SHD1_k127_345925_7 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 301.0
SHD1_k127_345925_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003252 275.0
SHD1_k127_345925_9 Cytidylate kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000003305 266.0
SHD1_k127_3461383_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 424.0
SHD1_k127_3461383_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 298.0
SHD1_k127_3461383_2 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001139 278.0
SHD1_k127_3461383_3 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000001381 88.0
SHD1_k127_3466395_0 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 605.0
SHD1_k127_3466395_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 534.0
SHD1_k127_3466395_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 501.0
SHD1_k127_3466395_3 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 460.0
SHD1_k127_3466395_4 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000007842 113.0
SHD1_k127_3466395_5 PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000000249 95.0
SHD1_k127_3467269_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 366.0
SHD1_k127_3467269_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000006439 170.0
SHD1_k127_3469805_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.939e-233 728.0
SHD1_k127_3469805_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.049e-229 714.0
SHD1_k127_3469805_2 4Fe-4S binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 380.0
SHD1_k127_3469805_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 341.0
SHD1_k127_3469805_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 343.0
SHD1_k127_3469805_5 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 340.0
SHD1_k127_3469805_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005595 256.0
SHD1_k127_3469805_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001748 211.0
SHD1_k127_3469805_8 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000001629 171.0
SHD1_k127_3480566_0 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000002864 183.0
SHD1_k127_3480566_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000005957 160.0
SHD1_k127_3480566_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000002514 158.0
SHD1_k127_3480566_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000003862 135.0
SHD1_k127_3480566_4 Transcriptional regulatory protein, C terminal - - - 0.00008276 55.0
SHD1_k127_3502498_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.24e-322 995.0
SHD1_k127_3502498_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.546e-292 914.0
SHD1_k127_3502498_2 hydrolase activity, hydrolyzing O-glycosyl compounds K05343 - 3.2.1.1,5.4.99.16 4.09e-286 885.0
SHD1_k127_3502498_3 1,4-alpha-glucan branching enzyme activity K01236 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576 3.2.1.141 1.509e-215 686.0
SHD1_k127_3502498_4 PFAM alpha amylase, catalytic K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000001309 253.0
SHD1_k127_350359_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.311e-249 788.0
SHD1_k127_350359_1 efflux transmembrane transporter activity - - - 1.186e-237 770.0
SHD1_k127_350359_10 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000004541 121.0
SHD1_k127_350359_11 sensor histidine kinase response - - - 0.00000000000000000000003491 107.0
SHD1_k127_350359_12 - - - - 0.0000000006952 70.0
SHD1_k127_350359_2 AMP-binding enzyme K01897 - 6.2.1.3 2.572e-229 724.0
SHD1_k127_350359_3 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 362.0
SHD1_k127_350359_4 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 291.0
SHD1_k127_350359_5 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000494 235.0
SHD1_k127_350359_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000003162 225.0
SHD1_k127_350359_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000009244 208.0
SHD1_k127_350359_8 - - - - 0.000000000000000000000000000000000002575 147.0
SHD1_k127_350359_9 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000007454 125.0
SHD1_k127_3505324_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.146e-305 971.0
SHD1_k127_3505324_1 glucose-6-phosphate isomerase activity K01810 - 5.3.1.9 8.533e-251 784.0
SHD1_k127_3505324_2 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 390.0
SHD1_k127_3505324_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 356.0
SHD1_k127_3505324_4 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000003348 189.0
SHD1_k127_3505324_5 - - - - 0.000000000000003718 89.0
SHD1_k127_3505324_6 Rhomboid family - - - 0.000000000002494 72.0
SHD1_k127_3505324_7 Peptidase M3A and M3B thimet oligopeptidase F - - - 0.0000000003281 73.0
SHD1_k127_3505324_8 peptidase activity, acting on L-amino acid peptides K20276 - - 0.000002374 61.0
SHD1_k127_3510837_0 Bacterial regulatory protein, Fis family - - - 5.853e-213 672.0
SHD1_k127_3510837_1 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 473.0
SHD1_k127_3510837_2 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 458.0
SHD1_k127_3510837_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001358 272.0
SHD1_k127_3510837_4 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000009699 113.0
SHD1_k127_3510837_5 - - - - 0.000000000000000000000001556 114.0
SHD1_k127_3510837_6 PAS domain K02668 - 2.7.13.3 0.000000000000000648 78.0
SHD1_k127_3517329_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 2.425e-213 675.0
SHD1_k127_3517329_1 PFAM Cys Met metabolism K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 547.0
SHD1_k127_3517329_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000006859 217.0
SHD1_k127_3524490_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 509.0
SHD1_k127_3524490_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 438.0
SHD1_k127_3524490_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000002695 244.0
SHD1_k127_3524490_3 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000002172 207.0
SHD1_k127_3530145_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000164 282.0
SHD1_k127_3530145_1 Protein of unknown function (DUF2911) - - - 0.0000000003102 71.0
SHD1_k127_3536189_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 370.0
SHD1_k127_3536189_1 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 361.0
SHD1_k127_3536189_2 Family of unknown function (DUF5335) - - - 0.000000000000000000000000000000001645 141.0
SHD1_k127_3536189_3 PFAM UspA domain protein - - - 0.0007513 51.0
SHD1_k127_3536990_0 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 505.0
SHD1_k127_3536990_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 410.0
SHD1_k127_3536990_2 - - - - 0.00000000000000000000000000000000000000000000001816 183.0
SHD1_k127_3536990_3 AraC-like ligand binding domain - - - 0.0000000000000000000000000008982 116.0
SHD1_k127_3545448_0 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 539.0
SHD1_k127_3545448_1 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 362.0
SHD1_k127_3545448_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 352.0
SHD1_k127_3545448_3 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000000000000001038 222.0
SHD1_k127_3545448_4 Cupin domain - - - 0.0000000000000000000000000000000000000000000001614 173.0
SHD1_k127_3545448_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000001709 176.0
SHD1_k127_3558068_0 LVIVD repeat - - - 1.505e-207 666.0
SHD1_k127_3558068_1 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 372.0
SHD1_k127_3558068_2 Domain of unknown function (DUF4142) - - - 0.00000000000000000000000000000000000000000000000000000000000005362 220.0
SHD1_k127_3564440_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 596.0
SHD1_k127_3564440_1 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 505.0
SHD1_k127_3564440_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 387.0
SHD1_k127_3564440_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 376.0
SHD1_k127_3564440_4 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 352.0
SHD1_k127_3564440_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000008604 203.0
SHD1_k127_3564440_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000009929 119.0
SHD1_k127_3564440_7 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000002716 113.0
SHD1_k127_3564440_8 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000002274 103.0
SHD1_k127_3567511_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 539.0
SHD1_k127_3567511_1 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000697 213.0
SHD1_k127_3567511_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000001016 147.0
SHD1_k127_3599170_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 562.0
SHD1_k127_3599170_1 - - - - 0.00000000000000000000000000000000000000000000000000001613 204.0
SHD1_k127_3599170_2 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000002238 184.0
SHD1_k127_3599170_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000004659 152.0
SHD1_k127_359965_0 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 592.0
SHD1_k127_359965_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 575.0
SHD1_k127_359965_2 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006277 252.0
SHD1_k127_359965_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.000000000000000000000000000000000000000000000000000000005076 216.0
SHD1_k127_359965_4 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000004327 180.0
SHD1_k127_359965_5 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000001061 167.0
SHD1_k127_3601287_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 406.0
SHD1_k127_3601287_1 ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 387.0
SHD1_k127_3611681_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1058.0
SHD1_k127_3611681_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
SHD1_k127_3611681_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 321.0
SHD1_k127_3611681_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000002749 136.0
SHD1_k127_361754_0 Polysaccharide biosynthesis protein K03328 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 353.0
SHD1_k127_361754_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006905 279.0
SHD1_k127_361754_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007959 288.0
SHD1_k127_361754_3 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000003192 185.0
SHD1_k127_361754_4 High confidence in function and specificity - - - 0.0000000000000000000000000000000000005097 155.0
SHD1_k127_361754_5 polysaccharide export - - - 0.0000000000000000000000000000000007493 142.0
SHD1_k127_361754_6 Histidine kinase - - - 0.00000000003129 70.0
SHD1_k127_3628271_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 568.0
SHD1_k127_3628271_1 FAD binding domain K05712 - 1.14.13.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 578.0
SHD1_k127_3628271_10 Domain of unknown function (DUF1989) - - - 0.000000000000000000000000000000000000000000000000000001119 201.0
SHD1_k127_3628271_11 negative regulation of transcription, DNA-templated - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000001165 146.0
SHD1_k127_3628271_12 methyltransferase activity - - - 0.00000000000000000000008996 107.0
SHD1_k127_3628271_2 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 473.0
SHD1_k127_3628271_3 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 462.0
SHD1_k127_3628271_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 359.0
SHD1_k127_3628271_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 330.0
SHD1_k127_3628271_6 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001049 285.0
SHD1_k127_3628271_7 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000943 253.0
SHD1_k127_3628271_8 PFAM acyltransferase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002645 252.0
SHD1_k127_3628271_9 Carboxymuconolactone decarboxylase family K14727 - 3.1.1.24,4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000001804 241.0
SHD1_k127_3653666_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 407.0
SHD1_k127_3653666_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 325.0
SHD1_k127_3653666_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000002304 219.0
SHD1_k127_3653666_3 Rhodanese Homology Domain K01069 - 3.1.2.6 0.0000000000000000000002614 100.0
SHD1_k127_367137_0 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002122 298.0
SHD1_k127_367137_1 TPR repeat - - - 0.00000000000000000000000000000000000000000008308 177.0
SHD1_k127_367137_2 lactoylglutathione lyase activity - - - 0.0000000000000000001682 94.0
SHD1_k127_3672134_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 496.0
SHD1_k127_3672134_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 317.0
SHD1_k127_3672134_2 FHA domain - - - 0.000000000000000000000000000000001025 142.0
SHD1_k127_3689185_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 479.0
SHD1_k127_3689185_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 441.0
SHD1_k127_3689185_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000718 69.0
SHD1_k127_369282_0 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 565.0
SHD1_k127_369282_1 Alanine racemase K19967 - 4.1.2.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 445.0
SHD1_k127_369282_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 300.0
SHD1_k127_369282_3 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000004459 208.0
SHD1_k127_369282_4 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000004208 185.0
SHD1_k127_369282_5 Dehydrogenase E1 component - - - 0.000000000000001683 81.0
SHD1_k127_369282_6 - - - - 0.0000000002237 65.0
SHD1_k127_3693126_0 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 352.0
SHD1_k127_3693126_1 Beta-lactamase - - - 0.00000000008046 73.0
SHD1_k127_3703315_0 Putative glucoamylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 497.0
SHD1_k127_3703315_1 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 488.0
SHD1_k127_3703315_2 ABC-type sugar transport systems, permease components K02025 - - 0.000000000000000000000000000000000000000000000000000008408 201.0
SHD1_k127_3710361_0 oligopeptide transporter, OPT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 624.0
SHD1_k127_3710361_1 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 522.0
SHD1_k127_3710361_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 435.0
SHD1_k127_3710361_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 341.0
SHD1_k127_3710361_4 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000277 290.0
SHD1_k127_3710361_5 extracellular polysaccharide biosynthetic process K13582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009463 248.0
SHD1_k127_3710361_6 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000001241 250.0
SHD1_k127_3710361_7 Yip1 domain - - - 0.00003091 55.0
SHD1_k127_3713854_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 456.0
SHD1_k127_3713854_1 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 357.0
SHD1_k127_3713854_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 318.0
SHD1_k127_3713854_3 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000005487 204.0
SHD1_k127_3728624_0 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 434.0
SHD1_k127_3728624_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 407.0
SHD1_k127_3728624_2 Lysine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000005832 198.0
SHD1_k127_3728624_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03753,K13818 - 2.7.7.77 0.0000000000000000001592 94.0
SHD1_k127_3733305_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 574.0
SHD1_k127_3733305_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 560.0
SHD1_k127_3733305_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 368.0
SHD1_k127_3733305_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002606 275.0
SHD1_k127_3733305_4 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000003788 239.0
SHD1_k127_3733305_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000435 175.0
SHD1_k127_3733305_6 Protein of unknown function (DUF983) - - - 0.000000000000000000000000001928 117.0
SHD1_k127_3739972_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 492.0
SHD1_k127_3739972_1 isochorismatase hydrolase - - - 0.00000000000000000000000001431 112.0
SHD1_k127_3748479_0 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 2.236e-238 745.0
SHD1_k127_3748479_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 423.0
SHD1_k127_3748479_2 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 420.0
SHD1_k127_3748479_3 Lipopolysaccharide kinase (Kdo/WaaP) family K11211 - 2.7.1.166 0.000000000000000000000000000000000000000000000000000001342 201.0
SHD1_k127_3748479_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000006515 191.0
SHD1_k127_3748479_5 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000518 182.0
SHD1_k127_3748479_6 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000002574 180.0
SHD1_k127_3748479_7 Glycosyl transferase, family 2 - - - 0.00000000000000000000005125 102.0
SHD1_k127_3748479_9 PFAM glycosyl transferase family 9 - - - 0.000000001929 64.0
SHD1_k127_3749982_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.6e-313 972.0
SHD1_k127_3749982_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.229e-197 622.0
SHD1_k127_3749982_2 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 494.0
SHD1_k127_3749982_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 416.0
SHD1_k127_3749982_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 396.0
SHD1_k127_3749982_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000001206 108.0
SHD1_k127_3756660_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 342.0
SHD1_k127_3756660_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 313.0
SHD1_k127_3756660_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000001029 215.0
SHD1_k127_3756660_3 Cytochrome c K00376,K02305,K17760 - 1.1.9.1,1.7.2.4 0.00000000000000000000000000000000000000000000000000000000002953 214.0
SHD1_k127_3756660_4 Multicopper oxidase - - - 0.000000000000000000000000000000004074 129.0
SHD1_k127_3768375_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1296.0
SHD1_k127_3768375_1 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 1.474e-230 729.0
SHD1_k127_3768375_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 506.0
SHD1_k127_3768375_3 - - - - 0.00000000000000000000000000000000000007779 152.0
SHD1_k127_3772852_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001856 241.0
SHD1_k127_3772852_1 CheC-like family K03410 - - 0.00000000000000000000000000000000000000000007463 168.0
SHD1_k127_3772852_2 P2 response regulator binding domain K03407 - 2.7.13.3 0.0000001912 53.0
SHD1_k127_3777343_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 623.0
SHD1_k127_3777343_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 423.0
SHD1_k127_3777343_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 336.0
SHD1_k127_3777343_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000002137 149.0
SHD1_k127_3788273_0 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 547.0
SHD1_k127_3788273_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009974 273.0
SHD1_k127_3788273_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000003658 220.0
SHD1_k127_3797312_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 8.77e-250 775.0
SHD1_k127_3797312_1 Pyridoxal-dependent decarboxylase conserved domain K00486,K01593 - 1.14.13.9,4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 381.0
SHD1_k127_3797312_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005333 262.0
SHD1_k127_3797312_4 - - - - 0.0000000000000006976 79.0
SHD1_k127_3798229_0 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 303.0
SHD1_k127_3798229_1 transferase activity, transferring glycosyl groups K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 302.0
SHD1_k127_3798229_2 O-Antigen ligase - - - 0.00000000000000000000000000000000000001591 160.0
SHD1_k127_3798229_3 PFAM Polysaccharide deacetylase - - - 0.0000000000003285 82.0
SHD1_k127_3805944_0 Carboxyl transferase domain - - - 1.089e-271 849.0
SHD1_k127_3805944_1 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 544.0
SHD1_k127_3805944_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 406.0
SHD1_k127_3805944_3 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000004299 236.0
SHD1_k127_3805944_4 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 0.00000000000000000000000000003885 117.0
SHD1_k127_3822201_0 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009797 279.0
SHD1_k127_3822201_1 Tryptophan-rich sensory protein K05770 - - 0.0000000000000000000000000000000000000000000000000002878 190.0
SHD1_k127_3822201_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000004296 163.0
SHD1_k127_3822201_3 Belongs to the peptidase M16 family K07263 - - 0.000007993 53.0
SHD1_k127_3832636_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 516.0
SHD1_k127_3832636_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000007662 154.0
SHD1_k127_3849688_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1351.0
SHD1_k127_3849688_1 4Fe-4S binding domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 392.0
SHD1_k127_3871242_0 Fumarase C C-terminus K01744 - 4.3.1.1 1.988e-211 670.0
SHD1_k127_3871242_1 hydroperoxide reductase activity - - - 0.000000001405 61.0
SHD1_k127_3881643_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 440.0
SHD1_k127_3881643_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 360.0
SHD1_k127_3881643_2 - - - - 0.0000000000002878 77.0
SHD1_k127_3913420_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.796e-244 771.0
SHD1_k127_3913420_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 524.0
SHD1_k127_3913420_10 PTS system fructose IIA component K02744 - - 0.0000136 50.0
SHD1_k127_3913420_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 520.0
SHD1_k127_3913420_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 378.0
SHD1_k127_3913420_4 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002851 269.0
SHD1_k127_3913420_5 PTS system sorbose-specific iic component K02795 - - 0.00000000000000000000000000000000000000000000000000000000000000204 224.0
SHD1_k127_3913420_6 PTS system sorbose subfamily IIB component K19507 - - 0.000000000000000000000000000000000000000000000000000000000002112 213.0
SHD1_k127_3913420_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000003446 147.0
SHD1_k127_3913420_8 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000000000325 132.0
SHD1_k127_3913420_9 PTS system fructose IIA component K02744 - - 0.0000000001919 64.0
SHD1_k127_3922471_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 419.0
SHD1_k127_3922471_1 - - - - 0.00000000000000000000000000004672 124.0
SHD1_k127_3922471_2 ArsR family transcriptional - - - 0.000000000000000000001263 98.0
SHD1_k127_3932665_0 Isocitrate lyase K01637 - 4.1.3.1 7.986e-210 659.0
SHD1_k127_3932665_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008489 276.0
SHD1_k127_3932665_2 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.000003223 51.0
SHD1_k127_3938284_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.526e-285 895.0
SHD1_k127_3938284_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 610.0
SHD1_k127_3938284_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 477.0
SHD1_k127_3938284_3 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 399.0
SHD1_k127_3938284_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000007965 106.0
SHD1_k127_393938_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 429.0
SHD1_k127_393938_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 359.0
SHD1_k127_393938_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 362.0
SHD1_k127_393938_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 349.0
SHD1_k127_393938_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000006971 183.0
SHD1_k127_393938_6 - - - - 0.00000003031 56.0
SHD1_k127_3948060_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 508.0
SHD1_k127_3948060_1 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 432.0
SHD1_k127_3948060_2 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008591 274.0
SHD1_k127_3948060_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000002704 233.0
SHD1_k127_3948060_4 - - - - 0.00000000000000000000000000000000000000000000000000000000001776 211.0
SHD1_k127_3948060_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000001407 177.0
SHD1_k127_3948060_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000024 154.0
SHD1_k127_3948060_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000005272 110.0
SHD1_k127_3948060_8 Glycosyl transferase, family 9 K02841,K02843,K02847,K02849,K21003 - - 0.00000000000008852 78.0
SHD1_k127_395953_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 321.0
SHD1_k127_395953_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000004971 194.0
SHD1_k127_3978861_0 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 446.0
SHD1_k127_3978861_1 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 356.0
SHD1_k127_3978861_2 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000002758 173.0
SHD1_k127_3978861_3 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000000000000001095 126.0
SHD1_k127_3984132_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000001538 244.0
SHD1_k127_3984132_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000009058 178.0
SHD1_k127_3984132_2 Putative glycolipid-binding K09957 - - 0.000000000000000000000000000000000000000008812 161.0
SHD1_k127_3990112_0 POT family K03305 - - 2.744e-197 627.0
SHD1_k127_3990112_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 482.0
SHD1_k127_3990112_2 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 488.0
SHD1_k127_3990112_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 409.0
SHD1_k127_3990112_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002884 261.0
SHD1_k127_4000224_0 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 601.0
SHD1_k127_4000224_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 551.0
SHD1_k127_4000224_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 519.0
SHD1_k127_4000224_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003315 261.0
SHD1_k127_4000224_4 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000004653 241.0
SHD1_k127_4000224_5 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000000000000000000000002608 211.0
SHD1_k127_4000224_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000971 153.0
SHD1_k127_4001743_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 1.329e-211 664.0
SHD1_k127_4001743_1 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 406.0
SHD1_k127_4001743_2 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.000000000000000000000000000000000000009185 148.0
SHD1_k127_4009313_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.565e-294 918.0
SHD1_k127_4009313_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 441.0
SHD1_k127_4009313_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000002376 235.0
SHD1_k127_4009313_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000007807 192.0
SHD1_k127_4034817_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 507.0
SHD1_k127_4034817_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 287.0
SHD1_k127_4034817_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000001173 242.0
SHD1_k127_4034817_3 Bacterial Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001498 253.0
SHD1_k127_4034817_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000008931 205.0
SHD1_k127_4034817_5 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000907 197.0
SHD1_k127_4051089_0 polyketide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 299.0
SHD1_k127_4053839_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 1.707e-215 677.0
SHD1_k127_4053839_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 566.0
SHD1_k127_4053839_10 NDK K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000003656 195.0
SHD1_k127_4053839_11 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000006622 194.0
SHD1_k127_4053839_12 Ribosomal L32p protein family K02911 - - 0.0000000000000000000000003327 105.0
SHD1_k127_4053839_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 477.0
SHD1_k127_4053839_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 469.0
SHD1_k127_4053839_4 Uncharacterised protein family (UPF0182) K09118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 470.0
SHD1_k127_4053839_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 402.0
SHD1_k127_4053839_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 365.0
SHD1_k127_4053839_7 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 314.0
SHD1_k127_4053839_8 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000001525 265.0
SHD1_k127_4053839_9 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000000000000001147 200.0
SHD1_k127_4056575_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.706e-301 944.0
SHD1_k127_4056575_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 595.0
SHD1_k127_4056575_10 response to copper ion K07156,K07245,K14166 - - 0.00000000007885 74.0
SHD1_k127_4056575_11 Tyrosine kinase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001813 63.0
SHD1_k127_4056575_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 569.0
SHD1_k127_4056575_3 PhoQ Sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 493.0
SHD1_k127_4056575_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 336.0
SHD1_k127_4056575_5 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 310.0
SHD1_k127_4056575_6 Putative ABC exporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001407 293.0
SHD1_k127_4056575_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000001263 206.0
SHD1_k127_4056575_8 Bacterial Ig-like domain 2 - - - 0.000000000000000000000000000000000000000000000000000001142 208.0
SHD1_k127_4056575_9 transcriptional regulator - - - 0.0000000000000000001544 96.0
SHD1_k127_4058986_0 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001559 276.0
SHD1_k127_4058986_1 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000003561 217.0
SHD1_k127_4058986_2 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000001204 141.0
SHD1_k127_4062826_0 TonB-dependent receptor - - - 2.666e-232 755.0
SHD1_k127_4062826_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000004126 247.0
SHD1_k127_4062826_2 TonB-dependent receptor - - - 0.0000000000000000000002829 97.0
SHD1_k127_4062826_3 Transcriptional regulatory protein, C terminal - - - 0.00000000008108 62.0
SHD1_k127_406728_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 386.0
SHD1_k127_406728_1 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 347.0
SHD1_k127_406728_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000002284 235.0
SHD1_k127_406728_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000002354 224.0
SHD1_k127_406728_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000001284 230.0
SHD1_k127_406728_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000002304 213.0
SHD1_k127_406728_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000002406 209.0
SHD1_k127_406728_7 - - - - 0.00000000000000000000000000000000000000000002738 172.0
SHD1_k127_406728_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000009608 148.0
SHD1_k127_406728_9 Ribosomal protein L36 K02919 - - 0.0000000000000003299 79.0
SHD1_k127_4070936_0 cellulose binding - - - 1.009e-232 752.0
SHD1_k127_4070936_1 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005238 297.0
SHD1_k127_4070936_2 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000881 254.0
SHD1_k127_4070936_3 Peptidase, M20 - - - 0.000001979 56.0
SHD1_k127_4073094_0 MMPL family K18138 - - 0.0 1194.0
SHD1_k127_4073094_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 346.0
SHD1_k127_4073094_2 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000002203 196.0
SHD1_k127_4079834_0 copper-translocating P-type ATPase K01533 - 3.6.3.4 2.383e-274 859.0
SHD1_k127_4079834_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 538.0
SHD1_k127_4079834_2 Protein of unknown function (DUF1698) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 398.0
SHD1_k127_4079834_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 358.0
SHD1_k127_4079834_4 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 363.0
SHD1_k127_4079834_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000002883 158.0
SHD1_k127_4079834_6 Flavin reductase like domain - - - 0.000000000000000000000000000000000000003304 157.0
SHD1_k127_4080747_0 AAA domain K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 488.0
SHD1_k127_4080747_1 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 421.0
SHD1_k127_4080747_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000003199 224.0
SHD1_k127_4080747_3 - K14340 - - 0.00000000000000000000000000000000000000000000000001027 199.0
SHD1_k127_4080747_4 PFAM CHAD domain containing protein - - - 0.0000000000000000000000003652 119.0
SHD1_k127_4082929_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 3.475e-315 988.0
SHD1_k127_4082929_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.39e-283 887.0
SHD1_k127_4082929_2 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 386.0
SHD1_k127_4082929_3 Succinyl-CoA ligase like flavodoxin domain - - - 0.000000000000000000000000000000000000000000000000000000001556 207.0
SHD1_k127_4085512_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 363.0
SHD1_k127_4085512_1 Thiolase, C-terminal domain K02615 - 2.3.1.174,2.3.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003194 270.0
SHD1_k127_4089759_0 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000003798 205.0
SHD1_k127_4089759_1 mitochondrial gene expression K02935 - - 0.00001217 53.0
SHD1_k127_4115228_0 PFAM Aminotransferase class I and II K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 312.0
SHD1_k127_4115228_1 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.000000000000000000000000000000000000000000000000002594 196.0
SHD1_k127_4115228_2 GtrA-like protein K00995 - 2.7.8.5 0.00000000000000000000000000003158 126.0
SHD1_k127_4115228_3 lipid kinase activity - - - 0.0000000000000000000000006271 117.0
SHD1_k127_4115228_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000005393 67.0
SHD1_k127_4121329_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 610.0
SHD1_k127_4121329_1 Mo-molybdopterin cofactor metabolic process K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000002382 238.0
SHD1_k127_4121329_2 Peptidase, M23 - - - 0.00000000000000000000000000000000000004609 154.0
SHD1_k127_4121329_3 tRNA synthetases class I (M) K01874 - 6.1.1.10 0.00000002403 55.0
SHD1_k127_4128862_0 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 453.0
SHD1_k127_4128862_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 347.0
SHD1_k127_4128862_2 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 336.0
SHD1_k127_4128862_3 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 332.0
SHD1_k127_4128862_4 macromolecule localization K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001661 255.0
SHD1_k127_4128862_7 Tetratricopeptide repeat-like domain - - - 0.000001749 55.0
SHD1_k127_4131958_0 Phosphate acetyl/butaryl transferase K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.0 1117.0
SHD1_k127_4131958_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.843e-261 815.0
SHD1_k127_4131958_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 552.0
SHD1_k127_4131958_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 387.0
SHD1_k127_4131958_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 370.0
SHD1_k127_4131958_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 370.0
SHD1_k127_4131958_6 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000000000003207 168.0
SHD1_k127_4131958_7 Part of the ABC transporter FtsEX involved in K09811 - - 0.0000000000000000000000000000000000006671 142.0
SHD1_k127_4131958_8 - - - - 0.0000000000000002762 79.0
SHD1_k127_4155108_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 519.0
SHD1_k127_4155108_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 426.0
SHD1_k127_4155108_2 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 364.0
SHD1_k127_4155108_3 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 341.0
SHD1_k127_4155108_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008396 284.0
SHD1_k127_4155108_5 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000000000000000000000001412 214.0
SHD1_k127_4155108_6 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000004377 180.0
SHD1_k127_4155108_7 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000767 173.0
SHD1_k127_4155108_8 YdjC-like protein - - - 0.000000000000000000000000000000001607 140.0
SHD1_k127_4155108_9 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000001604 92.0
SHD1_k127_4168557_0 FAD dependent oxidoreductase - - - 9.07e-237 742.0
SHD1_k127_4168557_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001528 272.0
SHD1_k127_4168557_2 Prolyl oligopeptidase family - - - 0.0000000000000000000000000001594 116.0
SHD1_k127_4181027_0 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 452.0
SHD1_k127_4181027_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 432.0
SHD1_k127_4181027_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002205 284.0
SHD1_k127_4181027_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.0000000000000000000000000000000002342 141.0
SHD1_k127_4181027_4 Belongs to the ompA family K03286 - - 0.00000000000000000008046 101.0
SHD1_k127_4181027_5 PFAM Chemotaxis methyl-accepting receptor, signalling K03406 - - 0.000000000000000000344 101.0
SHD1_k127_4181027_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000004884 64.0
SHD1_k127_4184454_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008608 267.0
SHD1_k127_4184454_1 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001562 276.0
SHD1_k127_4184454_2 Arginine deiminase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000002987 237.0
SHD1_k127_4193769_0 Elongation factor G C-terminus K06207 - - 5.428e-307 950.0
SHD1_k127_4193769_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 559.0
SHD1_k127_4193769_2 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 325.0
SHD1_k127_4193769_3 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008324 276.0
SHD1_k127_4193769_4 - - - - 0.0000001389 53.0
SHD1_k127_421001_0 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 607.0
SHD1_k127_421001_1 Peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 612.0
SHD1_k127_421001_2 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000002138 238.0
SHD1_k127_4215228_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 394.0
SHD1_k127_4215228_1 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 308.0
SHD1_k127_4215228_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000004671 219.0
SHD1_k127_4229187_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 513.0
SHD1_k127_4229187_1 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 387.0
SHD1_k127_4229187_10 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000002791 74.0
SHD1_k127_4229187_11 metallophosphoesterase K07098 - - 0.00000000002191 70.0
SHD1_k127_4229187_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 366.0
SHD1_k127_4229187_3 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 358.0
SHD1_k127_4229187_4 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 293.0
SHD1_k127_4229187_5 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000002408 180.0
SHD1_k127_4229187_6 - - - - 0.00000000000000000000000000004244 119.0
SHD1_k127_4229187_7 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000000000000006283 106.0
SHD1_k127_4229187_8 - - - - 0.00000000000000000000005913 104.0
SHD1_k127_4229187_9 Peptidase family M23 - - - 0.00000000000003799 82.0
SHD1_k127_4231050_0 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 595.0
SHD1_k127_4231050_1 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 374.0
SHD1_k127_4231050_2 RecQ zinc-binding K03654 - 3.6.4.12 0.00000000000000000002015 94.0
SHD1_k127_4250118_0 Insulinase (Peptidase family M16) K07263 - - 1.353e-320 1005.0
SHD1_k127_4250118_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 566.0
SHD1_k127_4250118_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 484.0
SHD1_k127_4250118_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 315.0
SHD1_k127_4250118_4 - - - - 0.00000000000000000000000000000000000000000000000000000000002915 217.0
SHD1_k127_4255598_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 364.0
SHD1_k127_4255598_1 Penicillinase repressor - - - 0.000000000000000000000000001066 116.0
SHD1_k127_4255598_2 - - - - 0.0000000000000005515 83.0
SHD1_k127_4281551_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 582.0
SHD1_k127_4281551_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 433.0
SHD1_k127_4281551_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 417.0
SHD1_k127_4281551_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000006157 265.0
SHD1_k127_4282249_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 4.807e-223 697.0
SHD1_k127_4282249_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 584.0
SHD1_k127_4282249_2 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 385.0
SHD1_k127_4282249_3 aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 352.0
SHD1_k127_4282249_4 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000003548 140.0
SHD1_k127_4282249_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000006163 117.0
SHD1_k127_4282249_6 Ribosomal protein S21 K02970 - - 0.00000001132 58.0
SHD1_k127_4287401_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 6.451e-215 679.0
SHD1_k127_4287401_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P) K07094 - - 0.00000000000000000000000000000000002471 145.0
SHD1_k127_4299089_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000002308 205.0
SHD1_k127_4299089_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000001045 157.0
SHD1_k127_4350028_0 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 593.0
SHD1_k127_4350028_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 386.0
SHD1_k127_4350028_2 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 348.0
SHD1_k127_4350028_3 acetyltransferase K01104 - 3.1.3.48 0.000000000000000000003807 99.0
SHD1_k127_4359188_0 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 588.0
SHD1_k127_4359188_1 ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 535.0
SHD1_k127_4359188_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000001005 209.0
SHD1_k127_4359188_11 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000002391 139.0
SHD1_k127_4359188_12 - - - - 0.000000000002741 80.0
SHD1_k127_4359188_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 532.0
SHD1_k127_4359188_3 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 513.0
SHD1_k127_4359188_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 474.0
SHD1_k127_4359188_5 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 444.0
SHD1_k127_4359188_6 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 418.0
SHD1_k127_4359188_7 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 409.0
SHD1_k127_4359188_8 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 419.0
SHD1_k127_4359188_9 oxidase, subunit K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 349.0
SHD1_k127_4383496_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 525.0
SHD1_k127_4383496_1 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 423.0
SHD1_k127_4383496_2 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000002014 230.0
SHD1_k127_4383496_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000002806 135.0
SHD1_k127_4397601_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 558.0
SHD1_k127_4397601_1 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 348.0
SHD1_k127_4397601_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 317.0
SHD1_k127_4397601_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 308.0
SHD1_k127_4397601_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000001091 214.0
SHD1_k127_4397601_5 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000000007854 175.0
SHD1_k127_4397601_6 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000002003 161.0
SHD1_k127_4397601_7 NADPH-dependent FMN reductase - - - 0.00000005396 57.0
SHD1_k127_4397601_8 - - - - 0.0001393 52.0
SHD1_k127_4419863_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 4.371e-258 813.0
SHD1_k127_4419863_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 387.0
SHD1_k127_4419863_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000007865 149.0
SHD1_k127_4423660_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 585.0
SHD1_k127_4423660_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000246 79.0
SHD1_k127_4429992_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 588.0
SHD1_k127_4429992_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 546.0
SHD1_k127_4429992_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 403.0
SHD1_k127_4429992_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001429 284.0
SHD1_k127_4429992_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000002941 251.0
SHD1_k127_4429992_5 Met-10+ like-protein K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 239.0
SHD1_k127_4429992_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000002482 168.0
SHD1_k127_4429992_7 HIT domain K02503 - - 0.00000000000000000000000000000000000000371 153.0
SHD1_k127_4429992_8 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0005446 45.0
SHD1_k127_4440708_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006355 244.0
SHD1_k127_4440708_1 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000001545 197.0
SHD1_k127_4440708_2 Rhomboid family - - - 0.000000003662 60.0
SHD1_k127_4440708_3 NeuB family K03856 - 2.5.1.54 0.0001746 44.0
SHD1_k127_4444172_0 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 385.0
SHD1_k127_4444172_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001214 261.0
SHD1_k127_4444172_3 Bacterial Ig-like domain 2 - - - 0.0001927 55.0
SHD1_k127_444686_0 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 365.0
SHD1_k127_444686_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008996 285.0
SHD1_k127_444686_2 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000001491 246.0
SHD1_k127_444686_3 - - - - 0.00000000007996 66.0
SHD1_k127_444686_4 Outer membrane efflux protein - - - 0.0000000533 54.0
SHD1_k127_4448801_0 - - - - 0.000000000000000000000000000000000000000000000000000006926 200.0
SHD1_k127_4448801_1 - - - - 0.000000000000000000000000000000000000000000002406 172.0
SHD1_k127_4452125_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 515.0
SHD1_k127_4452125_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 324.0
SHD1_k127_4452125_2 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 302.0
SHD1_k127_4452125_3 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000001828 132.0
SHD1_k127_4452125_4 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000001266 128.0
SHD1_k127_4452125_5 PFAM CheW domain protein K03408 - - 0.0000006957 60.0
SHD1_k127_4452125_6 Bacterial dnaA protein K02313 - - 0.0003215 45.0
SHD1_k127_4456054_0 Chain length determinant protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 571.0
SHD1_k127_4456054_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 441.0
SHD1_k127_4456054_2 diguanylate cyclase - - - 0.0001799 49.0
SHD1_k127_4459943_0 Thiolase, C-terminal domain K00632 - 2.3.1.16 2.134e-194 613.0
SHD1_k127_4459943_1 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002476 272.0
SHD1_k127_447772_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 6.257e-195 623.0
SHD1_k127_447772_1 Bacterial extracellular solute-binding proteins, family 3 K16254 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007403 280.0
SHD1_k127_447772_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002376 293.0
SHD1_k127_447772_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000001005 220.0
SHD1_k127_447772_4 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000003741 171.0
SHD1_k127_447772_5 Copper resistance protein D K07245,K14166 - - 0.000000003819 68.0
SHD1_k127_4491130_0 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000005112 237.0
SHD1_k127_4491130_1 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000009715 173.0
SHD1_k127_4491130_2 - - - - 0.000000000000000000007085 99.0
SHD1_k127_4517784_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 498.0
SHD1_k127_4517784_1 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 511.0
SHD1_k127_4517784_2 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 280.0
SHD1_k127_4517784_3 - - - - 0.00000000000000000000000000000000000000000000002566 186.0
SHD1_k127_4517784_4 Belongs to the bacterial solute-binding protein 9 family - - - 0.000000000001702 73.0
SHD1_k127_4521830_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000001719 210.0
SHD1_k127_4521830_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000001543 192.0
SHD1_k127_4521830_2 ig-like, plexins, transcription factors - - - 0.00000253 56.0
SHD1_k127_4535111_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.406e-258 810.0
SHD1_k127_4535111_1 Domain of unknown function (DUF3471) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 315.0
SHD1_k127_4535111_2 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001044 229.0
SHD1_k127_4535111_3 isomerase activity K07054 - - 0.000000000000000000000000000000000000000000000000001264 188.0
SHD1_k127_4535111_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000005831 122.0
SHD1_k127_4535111_5 - - - - 0.0006089 44.0
SHD1_k127_4537927_0 Aldehyde dehydrogenase family K22187 - - 2.815e-276 854.0
SHD1_k127_4537927_1 Bacterial regulatory protein, Fis family - - - 5.275e-205 649.0
SHD1_k127_4537927_2 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 338.0
SHD1_k127_4537927_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 336.0
SHD1_k127_4537927_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 303.0
SHD1_k127_4537927_5 Protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000007818 175.0
SHD1_k127_4537927_6 - - - - 0.0000000000000000000000000000000000309 142.0
SHD1_k127_4537927_7 - - - - 0.000000000000000000000000000006577 123.0
SHD1_k127_4537927_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000001243 116.0
SHD1_k127_4546917_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 455.0
SHD1_k127_4546917_1 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000002729 205.0
SHD1_k127_4547161_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.32e-277 872.0
SHD1_k127_4547161_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 574.0
SHD1_k127_4547161_10 - - - - 0.00000000000000000000000000000000000000000000000000000000006703 222.0
SHD1_k127_4547161_11 - - - - 0.000000000000000000000000000000004605 137.0
SHD1_k127_4547161_13 - - - - 0.00000000000000000000000005836 117.0
SHD1_k127_4547161_14 phosphorelay signal transduction system - - - 0.00000000000000000000005749 102.0
SHD1_k127_4547161_15 - - - - 0.0000000005772 69.0
SHD1_k127_4547161_2 Belongs to the bacterial solute-binding protein 9 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 484.0
SHD1_k127_4547161_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 457.0
SHD1_k127_4547161_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 441.0
SHD1_k127_4547161_5 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 422.0
SHD1_k127_4547161_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 368.0
SHD1_k127_4547161_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 334.0
SHD1_k127_4547161_8 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 325.0
SHD1_k127_4547161_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 308.0
SHD1_k127_4556390_0 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 1.853e-223 706.0
SHD1_k127_4556390_1 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 534.0
SHD1_k127_4556390_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 381.0
SHD1_k127_4556390_3 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001584 239.0
SHD1_k127_4556390_4 DinB superfamily - - - 0.000000000000000000000000000000000000000000005062 169.0
SHD1_k127_4556390_5 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000001703 125.0
SHD1_k127_4556390_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0004795 50.0
SHD1_k127_4565325_0 cell redox homeostasis K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 478.0
SHD1_k127_4565325_1 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 382.0
SHD1_k127_4565325_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 383.0
SHD1_k127_4565325_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000008069 216.0
SHD1_k127_4565325_4 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000005571 138.0
SHD1_k127_4565325_5 DinB superfamily - - - 0.000000000000000000000008089 104.0
SHD1_k127_4572741_0 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 505.0
SHD1_k127_4572741_1 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 442.0
SHD1_k127_4572741_2 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006281 265.0
SHD1_k127_4572741_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000008681 123.0
SHD1_k127_4572741_4 - - - - 0.000000000000009593 75.0
SHD1_k127_4572741_5 - - - - 0.0000002655 59.0
SHD1_k127_457303_0 response to abiotic stimulus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 324.0
SHD1_k127_457303_1 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 313.0
SHD1_k127_457303_2 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000002854 251.0
SHD1_k127_457303_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000003412 183.0
SHD1_k127_457303_4 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000003464 169.0
SHD1_k127_457303_5 acetyltransferase K03827 - - 0.000000000000000000000000000000000000000007585 158.0
SHD1_k127_457303_6 Protein of unknown function, DUF417 - - - 0.00000000000000000000000000000006096 132.0
SHD1_k127_4575298_0 Penicillin amidase - - - 0.0 1009.0
SHD1_k127_4575298_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 583.0
SHD1_k127_4575298_2 conserved protein (COG2071) K09166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 299.0
SHD1_k127_4575298_3 DinB family - - - 0.0000000000000000000000000000000000000000000000000000417 192.0
SHD1_k127_4575298_4 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000000000000000000000837 201.0
SHD1_k127_4575298_5 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000002169 185.0
SHD1_k127_4575298_6 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000000000000004763 165.0
SHD1_k127_4575298_7 - - - - 0.000000000000000001698 89.0
SHD1_k127_4575298_8 DinB superfamily - - - 0.0000000000002467 70.0
SHD1_k127_4575298_9 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000002908 72.0
SHD1_k127_4589490_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 483.0
SHD1_k127_4589490_1 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 408.0
SHD1_k127_4589490_2 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000001476 168.0
SHD1_k127_4589490_3 PFAM NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000002245 134.0
SHD1_k127_4589490_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000347 91.0
SHD1_k127_4600615_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 370.0
SHD1_k127_4600615_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003927 253.0
SHD1_k127_4628712_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.516e-205 657.0
SHD1_k127_4628712_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 608.0
SHD1_k127_4628712_11 Carbohydrate family 9 binding domain-like - - - 0.00000000000000002629 94.0
SHD1_k127_4628712_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 456.0
SHD1_k127_4628712_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 405.0
SHD1_k127_4628712_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 319.0
SHD1_k127_4628712_5 Releases the N-terminal proline from various substrates K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003458 282.0
SHD1_k127_4628712_6 Dienelactone hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000000736 218.0
SHD1_k127_4628712_7 SURF1 family K14998 - - 0.000000000000000000000000000000000000000000000000000000178 203.0
SHD1_k127_4628712_8 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000001067 178.0
SHD1_k127_4628712_9 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.0000000000000000000000000000000000000006874 153.0
SHD1_k127_4640924_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 586.0
SHD1_k127_4640924_1 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 475.0
SHD1_k127_4640924_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 429.0
SHD1_k127_4640924_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003761 286.0
SHD1_k127_4640924_4 - - - - 0.000000000000000000002511 96.0
SHD1_k127_4640924_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000006869 92.0
SHD1_k127_4652771_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000004214 226.0
SHD1_k127_4652771_1 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000004142 172.0
SHD1_k127_4652771_2 methylamine metabolic process K15977 - - 0.00000000000000000000000000000009247 131.0
SHD1_k127_4655779_0 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000131 133.0
SHD1_k127_4655779_1 Dodecin K09165 - - 0.000000000000000003335 85.0
SHD1_k127_4655779_2 - - - - 0.00000000003825 64.0
SHD1_k127_4655779_3 CsbD-like - - - 0.0000007448 53.0
SHD1_k127_4660162_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 448.0
SHD1_k127_4660162_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 303.0
SHD1_k127_4660162_2 epimerase dehydratase K07071 - - 0.00005644 45.0
SHD1_k127_4688648_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 533.0
SHD1_k127_4688648_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 306.0
SHD1_k127_4688648_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000003799 196.0
SHD1_k127_4693354_0 TonB dependent receptor K02014 - - 4.603e-201 659.0
SHD1_k127_4693354_1 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 407.0
SHD1_k127_4693354_2 Secreted and surface protein containing fasciclin-like repeats K19519 - - 0.000000000000000000000000000000000000000000000000000000000000000000004611 241.0
SHD1_k127_4693354_4 PFAM Pyrrolo-quinoline quinone K12132 - 2.7.11.1 0.000000000000000000264 94.0
SHD1_k127_4696319_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 334.0
SHD1_k127_4696319_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000004158 124.0
SHD1_k127_4702824_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 536.0
SHD1_k127_4702824_1 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000007778 204.0
SHD1_k127_4702824_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000002725 185.0
SHD1_k127_4711009_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.389e-223 701.0
SHD1_k127_4711009_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 504.0
SHD1_k127_4711009_2 Aminotransferase class I and II K14155 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 374.0
SHD1_k127_4711009_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 334.0
SHD1_k127_4711009_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001159 268.0
SHD1_k127_4711009_5 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006817 260.0
SHD1_k127_4711009_6 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000001784 222.0
SHD1_k127_4711009_7 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000001804 198.0
SHD1_k127_4711009_9 Tetratricopeptide repeat - - - 0.0000000321 66.0
SHD1_k127_4725512_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 485.0
SHD1_k127_4725512_1 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 397.0
SHD1_k127_4725512_2 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 325.0
SHD1_k127_4725512_3 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
SHD1_k127_4742044_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000689 273.0
SHD1_k127_4742044_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000001047 246.0
SHD1_k127_4764027_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 327.0
SHD1_k127_4764027_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004191 266.0
SHD1_k127_4764027_2 - - - - 0.000000000000000000000000000000000000000001123 166.0
SHD1_k127_4764110_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 495.0
SHD1_k127_4764110_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001955 261.0
SHD1_k127_4764110_2 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000000000000008154 172.0
SHD1_k127_4764110_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000001298 100.0
SHD1_k127_4764110_4 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000005428 101.0
SHD1_k127_4764110_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.1,3.5.4.33 0.0007807 45.0
SHD1_k127_4776337_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 2.393e-258 811.0
SHD1_k127_4776337_1 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 9.696e-197 623.0
SHD1_k127_4776337_2 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 377.0
SHD1_k127_4776337_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000001098 230.0
SHD1_k127_4776337_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000004763 211.0
SHD1_k127_4779526_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1169.0
SHD1_k127_4779526_1 Sodium:solute symporter family - - - 1.24e-218 690.0
SHD1_k127_4779526_2 C-terminus of AA_permease K03294 - - 7.152e-216 682.0
SHD1_k127_4779526_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 9.886e-209 665.0
SHD1_k127_4779526_4 Sodium:dicarboxylate symporter family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 539.0
SHD1_k127_4779526_5 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 500.0
SHD1_k127_4779526_6 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 432.0
SHD1_k127_4779526_7 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 331.0
SHD1_k127_4779526_8 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000000000000000000003634 181.0
SHD1_k127_4779526_9 Pyridoxal-dependent decarboxylase conserved domain K00486,K01593 - 1.14.13.9,4.1.1.105,4.1.1.28 0.00000000000002891 75.0
SHD1_k127_4793525_0 esterase - - - 5.423e-229 730.0
SHD1_k127_4793525_1 Putative diguanylate phosphodiesterase - - - 1.157e-201 661.0
SHD1_k127_4793525_10 - - - - 0.000000000001004 79.0
SHD1_k127_4793525_12 - - - - 0.0001309 53.0
SHD1_k127_4793525_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 420.0
SHD1_k127_4793525_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 388.0
SHD1_k127_4793525_4 Papain cysteine protease family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 336.0
SHD1_k127_4793525_5 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005284 280.0
SHD1_k127_4793525_6 Yip1 domain - - - 0.00000000000000000000000000000000000000000000000000000002201 204.0
SHD1_k127_4793525_7 Haloacid dehalogenase-like hydrolase K19270 - 3.1.3.23 0.0000000000000000000000000000000000000000000000002136 188.0
SHD1_k127_4793525_8 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000427 160.0
SHD1_k127_4793525_9 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000001855 154.0
SHD1_k127_482034_0 L-lysine catabolic process to acetate K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 315.0
SHD1_k127_482034_1 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 289.0
SHD1_k127_482034_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 292.0
SHD1_k127_4822266_0 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 616.0
SHD1_k127_4822266_1 Nitrite reductase, copper-dependent K00368,K08100 - 1.3.3.5,1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000007982 254.0
SHD1_k127_4822266_2 - - - - 0.000000000000000000000000000000000001026 147.0
SHD1_k127_4842917_0 FAD linked oxidase domain protein - - - 2.182e-246 769.0
SHD1_k127_4842917_1 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 537.0
SHD1_k127_4842917_2 cyclic nucleotide binding K12132,K20074 - 2.7.11.1,3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 338.0
SHD1_k127_4842917_3 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000000000000000008094 245.0
SHD1_k127_4850551_0 Glycosyl hydrolases family 2, TIM barrel domain K01190 - 3.2.1.23 3.591e-253 793.0
SHD1_k127_4850551_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.85e-221 706.0
SHD1_k127_4850551_10 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000004474 209.0
SHD1_k127_4850551_11 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000000000002043 194.0
SHD1_k127_4850551_12 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000009255 188.0
SHD1_k127_4850551_13 Transglycosylase associated protein - - - 0.0000000000000000000002443 102.0
SHD1_k127_4850551_14 von Willebrand factor type A domain K07114 - - 0.00000000000000000001279 105.0
SHD1_k127_4850551_15 trehalose biosynthetic process K00700,K05343,K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 0.00000000000000001236 94.0
SHD1_k127_4850551_2 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 439.0
SHD1_k127_4850551_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 396.0
SHD1_k127_4850551_4 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 308.0
SHD1_k127_4850551_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 300.0
SHD1_k127_4850551_6 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001257 290.0
SHD1_k127_4850551_7 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009541 288.0
SHD1_k127_4850551_8 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000001182 225.0
SHD1_k127_4850551_9 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000002191 220.0
SHD1_k127_4852370_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 396.0
SHD1_k127_4852370_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 327.0
SHD1_k127_4852370_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 301.0
SHD1_k127_4857639_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 522.0
SHD1_k127_4857639_1 Belongs to the HpcH HpaI aldolase family K18292 - 4.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 401.0
SHD1_k127_4857639_2 tRNA wobble adenosine to inosine editing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005595 256.0
SHD1_k127_4863414_0 glucan 1,4-alpha-glucosidase activity - - - 1.044e-267 835.0
SHD1_k127_4863414_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 550.0
SHD1_k127_4863414_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 289.0
SHD1_k127_4863414_3 lipase activity K15349 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006521 276.0
SHD1_k127_4863414_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003737 262.0
SHD1_k127_4863414_5 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003026 258.0
SHD1_k127_4863414_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000888 156.0
SHD1_k127_4863414_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000002864 83.0
SHD1_k127_4863414_8 - - - - 0.0000000000004167 81.0
SHD1_k127_4863414_9 Concanavalin A-like lectin/glucanases superfamily - - - 0.000004629 49.0
SHD1_k127_48969_0 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000003559 203.0
SHD1_k127_48969_1 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000009329 143.0
SHD1_k127_48969_2 - - - - 0.0000000000000000000000000000000001207 137.0
SHD1_k127_48969_3 TonB-dependent Receptor Plug - - - 0.000000000008507 78.0
SHD1_k127_4928034_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.827e-208 669.0
SHD1_k127_4928034_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 534.0
SHD1_k127_4928034_2 - - - - 0.0000000000000000000000000000000000000000000003108 176.0
SHD1_k127_4928034_3 Late competence development protein ComFB - - - 0.0000000398 62.0
SHD1_k127_4931025_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002258 302.0
SHD1_k127_4931025_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000845 278.0
SHD1_k127_4931025_2 Acyltransferase family - - - 0.00000000000000000000000000000000000000000009454 176.0
SHD1_k127_4931025_3 Helix-turn-helix XRE-family like proteins K14056 - - 0.00003431 51.0
SHD1_k127_4931025_4 phosphorelay signal transduction system - - - 0.0005876 47.0
SHD1_k127_4945410_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 317.0
SHD1_k127_4945410_1 DNA methyltransferase K07318 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000001132 217.0
SHD1_k127_4945410_2 - - - - 0.00000000000000000001308 96.0
SHD1_k127_4954230_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 369.0
SHD1_k127_4954230_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007821 284.0
SHD1_k127_4954230_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000002195 183.0
SHD1_k127_4954230_3 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000005331 143.0
SHD1_k127_4955083_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1095.0
SHD1_k127_4955083_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000002137 192.0
SHD1_k127_4955083_2 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000001095 169.0
SHD1_k127_4955083_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000004531 149.0
SHD1_k127_4975820_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 453.0
SHD1_k127_4975820_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000004751 270.0
SHD1_k127_4978930_0 Sortilin, neurotensin receptor 3, - - - 0.0 1255.0
SHD1_k127_4978930_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 619.0
SHD1_k127_4978930_2 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001195 278.0
SHD1_k127_4978930_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004951 256.0
SHD1_k127_4978930_4 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000006772 153.0
SHD1_k127_4978930_5 permease - - - 0.0002362 49.0
SHD1_k127_4979008_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 542.0
SHD1_k127_4979008_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 529.0
SHD1_k127_4979008_2 Aminotransferase class-III K03851,K15372 - 2.6.1.55,2.6.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 401.0
SHD1_k127_4979155_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.494e-301 934.0
SHD1_k127_4979155_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 338.0
SHD1_k127_4979155_2 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 337.0
SHD1_k127_4979155_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 303.0
SHD1_k127_4979155_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000001313 132.0
SHD1_k127_4979155_5 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000001286 60.0
SHD1_k127_4980336_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 423.0
SHD1_k127_4980336_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 375.0
SHD1_k127_4985347_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 385.0
SHD1_k127_4985347_1 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000001281 178.0
SHD1_k127_5001237_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 589.0
SHD1_k127_5001237_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000001895 237.0
SHD1_k127_501330_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 579.0
SHD1_k127_501330_1 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 524.0
SHD1_k127_501330_2 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 455.0
SHD1_k127_501330_3 chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 458.0
SHD1_k127_501330_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 332.0
SHD1_k127_501330_5 - - - - 0.0000000000000000000000000000000005805 134.0
SHD1_k127_5017018_0 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 409.0
SHD1_k127_5017018_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 434.0
SHD1_k127_5017018_2 Domain of unknown function (DUF4321) - - - 0.00000000000000000000000000000000000007957 144.0
SHD1_k127_5017018_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000001113 78.0
SHD1_k127_5026382_0 protein histidine kinase activity K03407,K07678 - 2.7.13.3 1.452e-219 702.0
SHD1_k127_5026382_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 300.0
SHD1_k127_5026382_2 Gas vesicle - - - 0.0000000000000000000000000000000000000000000000000004888 200.0
SHD1_k127_5026382_3 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.000000000000000000000000000000000000004098 147.0
SHD1_k127_5026382_4 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.00000000000000000000000000000000000002559 145.0
SHD1_k127_5026382_5 Gas vesicle protein K - - - 0.00000000000000000000000000000000001519 144.0
SHD1_k127_5026382_7 Gas vesicle synthesis protein GvpL/GvpF - - - 0.0000005662 60.0
SHD1_k127_5038093_0 RNA secondary structure unwinding K03724 - - 1.19e-272 863.0
SHD1_k127_5038093_1 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 7.118e-216 691.0
SHD1_k127_5038093_2 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 621.0
SHD1_k127_5038093_3 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 473.0
SHD1_k127_5038093_4 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 491.0
SHD1_k127_5038093_5 COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 479.0
SHD1_k127_5038093_6 Histidine kinase - - - 0.0000000000000000002926 102.0
SHD1_k127_5038093_7 Protein of unknown function (DUF1634) - - - 0.00000000008532 63.0
SHD1_k127_5053076_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001832 249.0
SHD1_k127_5053076_1 cyclic nucleotide-binding K10914 - - 0.000004461 59.0
SHD1_k127_5081851_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 597.0
SHD1_k127_5081851_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 563.0
SHD1_k127_5081851_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 422.0
SHD1_k127_5081851_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000001111 234.0
SHD1_k127_5081851_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000003833 203.0
SHD1_k127_5081851_5 biotin synthase K03523 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000002553 63.0
SHD1_k127_5096647_0 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 397.0
SHD1_k127_5096647_1 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 353.0
SHD1_k127_5096647_2 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000001153 196.0
SHD1_k127_5096647_3 Carboxymuconolactone decarboxylase family K01607,K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000001897 159.0
SHD1_k127_5096647_4 Putative cyclase - - - 0.000000000000000000000000000000000000008316 151.0
SHD1_k127_5096647_5 FAD binding domain K00481 - 1.14.13.2 0.000000000000000000000000000000000001196 139.0
SHD1_k127_5102454_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.219e-232 728.0
SHD1_k127_5102454_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 339.0
SHD1_k127_5102454_2 Transglycosylase associated protein - - - 0.00000000000000000002656 93.0
SHD1_k127_5102454_3 ABC transporter - - - 0.000000000000000006594 96.0
SHD1_k127_5128943_0 protein secretion by the type I secretion system K11085 - - 1.742e-245 773.0
SHD1_k127_5128943_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 598.0
SHD1_k127_5128943_2 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000000000000000006424 184.0
SHD1_k127_5128943_3 - - - - 0.0000000000000000004764 95.0
SHD1_k127_5128943_5 Forkhead associated domain - - - 0.0001007 52.0
SHD1_k127_5137855_0 cytochrome c oxidase subunit I K02274 - 1.9.3.1 1.652e-244 771.0
SHD1_k127_5137855_1 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 6.427e-209 668.0
SHD1_k127_5137855_2 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 610.0
SHD1_k127_5137855_3 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 394.0
SHD1_k127_5137855_4 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000002332 218.0
SHD1_k127_514452_0 Prolyl oligopeptidase family - - - 2.573e-208 664.0
SHD1_k127_5150768_0 Asparagine synthase K01953 - 6.3.5.4 3.264e-196 633.0
SHD1_k127_5150768_1 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000003334 233.0
SHD1_k127_5150768_2 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
SHD1_k127_5150768_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000003359 66.0
SHD1_k127_5158302_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 400.0
SHD1_k127_5158302_1 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 366.0
SHD1_k127_5162058_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 505.0
SHD1_k127_5162058_1 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000621 139.0
SHD1_k127_5162058_2 ThiS family K03636 - - 0.0000000000000000696 82.0
SHD1_k127_518858_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 459.0
SHD1_k127_518858_1 permease - - - 0.0000000000000000000000000007893 116.0
SHD1_k127_5191879_0 Tricorn protease homolog K08676 - - 8.388e-208 664.0
SHD1_k127_5191879_1 Tricorn protease homolog K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 559.0
SHD1_k127_5191879_2 Domain of unknown function (DUF3471) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 522.0
SHD1_k127_5192285_0 Protein of unknown function (DUF2723) - - - 3.353e-243 759.0
SHD1_k127_520344_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.682e-298 921.0
SHD1_k127_520344_1 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 415.0
SHD1_k127_520344_2 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 414.0
SHD1_k127_520344_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
SHD1_k127_520344_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K04040,K20616 - 2.5.1.133,2.5.1.62 0.00000000000000000000000000000000000000000000000000000000000000000001292 247.0
SHD1_k127_520344_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000003149 189.0
SHD1_k127_520344_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000001657 161.0
SHD1_k127_520344_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000005528 68.0
SHD1_k127_520344_8 lytic transglycosylase activity K08309 - - 0.000000003819 68.0
SHD1_k127_520344_9 Roadblock/LC7 domain K07131 - - 0.0000002634 53.0
SHD1_k127_5210709_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 579.0
SHD1_k127_5210709_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 415.0
SHD1_k127_5213049_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 574.0
SHD1_k127_5213049_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 540.0
SHD1_k127_5213049_10 Protein of unknown function (DUF3618) - - - 0.00000265 59.0
SHD1_k127_5213049_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 512.0
SHD1_k127_5213049_3 peptidase K01389,K01415,K07386 - 3.4.24.11,3.4.24.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 467.0
SHD1_k127_5213049_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000002108 263.0
SHD1_k127_5213049_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000001728 240.0
SHD1_k127_5213049_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000159 231.0
SHD1_k127_5213049_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000001255 151.0
SHD1_k127_5223414_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000004513 232.0
SHD1_k127_5223414_1 Domain of unknown function (DUF4974) K07165 - - 0.0000000000000000000000000000000000000000006261 171.0
SHD1_k127_5223414_2 ECF sigma factor K03088 - - 0.00000000000000000000000000000009136 132.0
SHD1_k127_5223414_3 Tetratricopeptide repeat - - - 0.00003861 55.0
SHD1_k127_5227179_0 4Fe-4S dicluster domain K00184 - - 0.0 1237.0
SHD1_k127_5227179_1 Polysulphide reductase, NrfD K00185 - - 8.763e-244 760.0
SHD1_k127_5227179_2 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 514.0
SHD1_k127_5227179_3 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006126 301.0
SHD1_k127_5227179_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006366 253.0
SHD1_k127_5227179_5 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000006508 232.0
SHD1_k127_5227179_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000001694 220.0
SHD1_k127_5227179_7 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000001673 197.0
SHD1_k127_5227179_8 copper resistance D domain protein K14166 - - 0.000000000001804 79.0
SHD1_k127_5227470_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.906e-247 813.0
SHD1_k127_5227470_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 600.0
SHD1_k127_5227470_2 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 479.0
SHD1_k127_5227470_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 436.0
SHD1_k127_5227470_4 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 357.0
SHD1_k127_5227470_5 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007332 289.0
SHD1_k127_5227470_6 creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001256 277.0
SHD1_k127_5227470_7 - - - - 0.000000000000000000000000000000000000000002453 172.0
SHD1_k127_5227470_8 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000009317 158.0
SHD1_k127_5227470_9 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000258 131.0
SHD1_k127_5248817_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 435.0
SHD1_k127_5248817_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 302.0
SHD1_k127_5248817_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000009025 194.0
SHD1_k127_5248817_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000014 155.0
SHD1_k127_5248817_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000001394 118.0
SHD1_k127_5252202_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 509.0
SHD1_k127_5252202_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 482.0
SHD1_k127_5252202_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 396.0
SHD1_k127_5254253_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 7.501e-198 622.0
SHD1_k127_5254253_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000007826 213.0
SHD1_k127_5254253_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000005759 76.0
SHD1_k127_5269050_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 371.0
SHD1_k127_5269050_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000006472 233.0
SHD1_k127_5269050_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000001995 155.0
SHD1_k127_5269050_3 Transport permease protein K01992 - - 0.0000000000000000000000000005073 124.0
SHD1_k127_5269050_4 Serine kinase of the HPr protein, regulates carbohydrate metabolism - - - 0.000000000000000432 89.0
SHD1_k127_5269050_5 Uncharacterised nucleotidyltransferase - - - 0.00000000000000158 89.0
SHD1_k127_5269050_6 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000002555 59.0
SHD1_k127_5269050_7 Transglutaminase-like superfamily - - - 0.0001684 50.0
SHD1_k127_5269504_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002192 272.0
SHD1_k127_5269504_1 cyclic nucleotide binding K12132,K20074 - 2.7.11.1,3.1.3.16 0.00000000000000000000000000000000000000000000000000003179 192.0
SHD1_k127_5269504_2 YXWGXW repeat (2 copies) - - - 0.000000000000001742 80.0
SHD1_k127_5287177_0 RecQ zinc-binding K03654 - 3.6.4.12 1.197e-229 719.0
SHD1_k127_5287177_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000002579 138.0
SHD1_k127_5299242_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 481.0
SHD1_k127_5299242_1 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 432.0
SHD1_k127_5299242_2 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006251 271.0
SHD1_k127_5299242_3 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000004414 248.0
SHD1_k127_5299242_4 Aminotransferase K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000008607 207.0
SHD1_k127_5299242_5 Protein of unknown function (DUF447) K09154 - - 0.0000000000000000000000000000000000000000000000000002125 189.0
SHD1_k127_5299242_6 Pterin 4 alpha carbinolamine dehydratase K01724,K11991 - 3.5.4.33,4.2.1.96 0.000000000000000000000000000000000000000000000000679 177.0
SHD1_k127_5311983_0 Bacterial dnaA protein K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 519.0
SHD1_k127_5311983_1 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 291.0
SHD1_k127_5311983_2 Tetratricopeptide repeat - - - 0.00000007246 63.0
SHD1_k127_5311983_3 Roadblock/LC7 domain - - - 0.0004594 51.0
SHD1_k127_5320511_0 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000002777 266.0
SHD1_k127_5320511_1 Domain of unknown function (DUF4198) - - - 0.00000000000000000000000000000000000000000000000009011 188.0
SHD1_k127_5320511_2 - - - - 0.000000000000000000000000000000000000000000004906 171.0
SHD1_k127_5320511_3 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000001475 154.0
SHD1_k127_5320511_4 Protein of unknown function, DUF488 - - - 0.000000000000000000000000001104 117.0
SHD1_k127_5320511_5 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000002097 88.0
SHD1_k127_5321207_0 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000002283 229.0
SHD1_k127_5328673_0 Cyclic nucleotide-monophosphate binding domain K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 410.0
SHD1_k127_5328673_1 Protein of unknown function (DUF2380) - - - 0.0002935 50.0
SHD1_k127_5347172_0 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 594.0
SHD1_k127_5347172_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 335.0
SHD1_k127_5347172_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000003103 227.0
SHD1_k127_5347172_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000001793 207.0
SHD1_k127_5347172_4 STAS domain K04749 - - 0.00000000000000000000000000000000000000000000000000000247 194.0
SHD1_k127_5347172_5 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000007623 149.0
SHD1_k127_5347172_6 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000000000000000000005956 115.0
SHD1_k127_5349295_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 447.0
SHD1_k127_5349295_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08313,K08314 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 0.00000000000000000000000000000000000000002258 159.0
SHD1_k127_5363943_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 329.0
SHD1_k127_5363943_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 328.0
SHD1_k127_5363943_2 Bax inhibitor 1 like - - - 0.00000000000000000000000000000000000000000000000000005642 197.0
SHD1_k127_5363943_3 Domain of unknown function (DUF4342) - - - 0.00000000000000000002401 94.0
SHD1_k127_5365241_0 Bacterial membrane protein YfhO - - - 9.047e-266 841.0
SHD1_k127_5365241_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 9.749e-244 762.0
SHD1_k127_5365241_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 444.0
SHD1_k127_5365241_3 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005571 247.0
SHD1_k127_5365241_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000001395 163.0
SHD1_k127_5365241_5 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0002762 46.0
SHD1_k127_5374507_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.946e-255 793.0
SHD1_k127_5377929_0 NAD synthase K01916 - 6.3.1.5 7.99e-247 776.0
SHD1_k127_5385061_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 385.0
SHD1_k127_5385061_1 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 356.0
SHD1_k127_5385061_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 316.0
SHD1_k127_5392854_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 377.0
SHD1_k127_5392854_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000002667 123.0
SHD1_k127_5399095_0 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 488.0
SHD1_k127_5399095_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002556 261.0
SHD1_k127_5406913_0 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 391.0
SHD1_k127_5406913_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000002817 151.0
SHD1_k127_5414768_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 417.0
SHD1_k127_5414768_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 381.0
SHD1_k127_5414768_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000001098 243.0
SHD1_k127_5414768_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000001175 209.0
SHD1_k127_5416776_0 Sortilin, neurotensin receptor 3, - - - 5.933e-246 784.0
SHD1_k127_5416776_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000005097 203.0
SHD1_k127_543102_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 626.0
SHD1_k127_543102_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 582.0
SHD1_k127_543102_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 487.0
SHD1_k127_543102_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 452.0
SHD1_k127_543102_4 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 365.0
SHD1_k127_543102_5 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000001764 237.0
SHD1_k127_543102_6 RNA secondary structure unwinding K03724 - - 0.000000000000000000000000000000000000000000000009317 174.0
SHD1_k127_543102_7 - - - - 0.000000000000000001436 96.0
SHD1_k127_5441968_0 X-Pro dipeptidyl-peptidase domain protein K06978 - - 5.486e-258 809.0
SHD1_k127_5441968_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 609.0
SHD1_k127_5441968_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 550.0
SHD1_k127_5441968_3 Uncharacterised conserved protein (DUF2156) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 392.0
SHD1_k127_5441968_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 305.0
SHD1_k127_5441968_5 NAD(P)H-binding - - - 0.000000000000000003357 87.0
SHD1_k127_5441968_6 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000001654 91.0
SHD1_k127_545507_0 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000203 204.0
SHD1_k127_545507_1 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000002809 192.0
SHD1_k127_5457651_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 357.0
SHD1_k127_5457651_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002133 247.0
SHD1_k127_5457651_2 - - - - 0.0000000000000000000000000000000000000000001675 166.0
SHD1_k127_5458802_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 3e-323 1054.0
SHD1_k127_5458802_1 (ABC) transporter K06147,K06148 - - 2.776e-220 703.0
SHD1_k127_5458802_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000001151 218.0
SHD1_k127_5458802_11 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000007329 191.0
SHD1_k127_5458802_12 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000001265 175.0
SHD1_k127_5458802_13 - - - - 0.000000000000000000000000000000000000000003833 164.0
SHD1_k127_5458802_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000001302 142.0
SHD1_k127_5458802_15 ATP-grasp domain - - - 0.0000000000000000000000000005499 121.0
SHD1_k127_5458802_16 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000005634 81.0
SHD1_k127_5458802_17 - - - - 0.000000195 59.0
SHD1_k127_5458802_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 585.0
SHD1_k127_5458802_3 Surface antigen K07277,K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 539.0
SHD1_k127_5458802_4 Domain of unknown function (DUF3471) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 462.0
SHD1_k127_5458802_5 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 426.0
SHD1_k127_5458802_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 364.0
SHD1_k127_5458802_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 360.0
SHD1_k127_5458802_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000003159 228.0
SHD1_k127_5458802_9 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000005465 224.0
SHD1_k127_5469234_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 467.0
SHD1_k127_5469234_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 436.0
SHD1_k127_5469234_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 369.0
SHD1_k127_5479612_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000433 229.0
SHD1_k127_5479612_1 - - - - 0.0000000000000000000000000000009319 129.0
SHD1_k127_5479612_2 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000000000003768 124.0
SHD1_k127_5479612_3 - - - - 0.00000000000000000000002859 100.0
SHD1_k127_5484683_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 356.0
SHD1_k127_5484683_1 Matrixin - - - 0.000000000000000000000000000000000000000000000000000000000000000000001268 246.0
SHD1_k127_5484683_2 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000003024 231.0
SHD1_k127_5484683_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000001819 89.0
SHD1_k127_5489351_0 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 499.0
SHD1_k127_5489351_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 368.0
SHD1_k127_5489351_2 Domain of unknown function (DUF892) - - - 0.0000000000000000000000000000000000000000000000003846 183.0
SHD1_k127_5489351_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000002328 124.0
SHD1_k127_5489351_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000001512 97.0
SHD1_k127_5490201_0 peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.0000000000000000000000000000000000000006944 171.0
SHD1_k127_5490201_1 - - - - 0.00000000000000001043 85.0
SHD1_k127_5490201_2 Glycosyl transferases group 1 K21001 - - 0.0000000006684 64.0
SHD1_k127_5490201_3 - - - - 0.0000001389 53.0
SHD1_k127_5494694_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1012.0
SHD1_k127_5494694_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.538e-233 739.0
SHD1_k127_5494694_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 563.0
SHD1_k127_5494694_3 BON domain - - - 0.0000000000000000000000000000000000000000001998 183.0
SHD1_k127_5501445_0 3-phosphoshikimate 1-carboxyvinyltransferase activity K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 486.0
SHD1_k127_5501445_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 434.0
SHD1_k127_5501445_2 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 357.0
SHD1_k127_5501445_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000008246 264.0
SHD1_k127_5501445_4 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000002 206.0
SHD1_k127_5501445_5 amino acid-binding ACT domain protein K00210,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.0000000000000000000006543 109.0
SHD1_k127_5501660_0 Peptidase family M13 K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 596.0
SHD1_k127_5501660_1 SMART helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 313.0
SHD1_k127_5501660_2 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
SHD1_k127_5501660_3 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000699 210.0
SHD1_k127_5501660_4 - - - - 0.00000000000000000000000000000000000000004499 160.0
SHD1_k127_5503308_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 468.0
SHD1_k127_5503308_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 448.0
SHD1_k127_5503308_2 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 457.0
SHD1_k127_5503308_3 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 374.0
SHD1_k127_5503308_4 lipopolysaccharide transmembrane transporter activity K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 310.0
SHD1_k127_5503308_5 Nitrogen fixation protein NifU - - - 0.000001436 53.0
SHD1_k127_562817_0 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 514.0
SHD1_k127_562817_1 HupF/HypC family K04653 - - 0.0000000000000000000000001987 108.0
SHD1_k127_562817_2 AIR synthase related protein, C-terminal domain K04655 - - 0.00000177 59.0
SHD1_k127_580061_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008363 266.0
SHD1_k127_580061_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000395 258.0
SHD1_k127_580061_2 Winged helix DNA-binding domain - - - 0.000000000002569 69.0
SHD1_k127_580257_0 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 511.0
SHD1_k127_580257_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 392.0
SHD1_k127_580257_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000003749 257.0
SHD1_k127_592298_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 550.0
SHD1_k127_592298_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000001222 194.0
SHD1_k127_592298_2 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000205 161.0
SHD1_k127_601876_0 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000004809 141.0
SHD1_k127_601876_1 Biopolymer transport protein ExbD/TolR - - - 0.000000001952 66.0
SHD1_k127_603387_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 382.0
SHD1_k127_603387_1 - - - - 0.000000000000000000000000000000000000000000628 162.0
SHD1_k127_616589_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.355e-200 638.0
SHD1_k127_616589_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 457.0
SHD1_k127_616589_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 403.0
SHD1_k127_616589_3 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 355.0
SHD1_k127_616589_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 317.0
SHD1_k127_616589_5 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000001165 220.0
SHD1_k127_616589_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0008789 47.0
SHD1_k127_618719_0 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.0 1108.0
SHD1_k127_618719_1 Succinyl-CoA ligase like flavodoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 600.0
SHD1_k127_618719_2 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 588.0
SHD1_k127_618719_3 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
SHD1_k127_618719_4 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000003329 179.0
SHD1_k127_618719_5 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000003097 125.0
SHD1_k127_626500_0 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 475.0
SHD1_k127_626500_1 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000009539 226.0
SHD1_k127_634424_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 467.0
SHD1_k127_634424_1 Flavin-binding monooxygenase-like K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 466.0
SHD1_k127_634424_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 288.0
SHD1_k127_634424_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004052 233.0
SHD1_k127_634424_4 DinB family - - - 0.00000000000000000000000000000000003341 140.0
SHD1_k127_634424_5 Cell wall-active antibiotics response 4TMS YvqF - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000002159 97.0
SHD1_k127_64931_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.599e-279 878.0
SHD1_k127_64931_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008453 78.0
SHD1_k127_660458_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 482.0
SHD1_k127_660458_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 359.0
SHD1_k127_660458_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000001053 220.0
SHD1_k127_660458_3 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000004439 121.0
SHD1_k127_660458_4 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000006245 104.0
SHD1_k127_660458_5 Outer membrane protein beta-barrel domain - - - 0.0000000001237 69.0
SHD1_k127_668065_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009423 282.0
SHD1_k127_668065_1 TraM recognition site of TraD and TraG - - - 0.00000000000000000000000000000000000000000000000000000001084 225.0
SHD1_k127_678706_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 360.0
SHD1_k127_678706_1 ABC transporter K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 354.0
SHD1_k127_678706_2 permease K02011 - - 0.000000000000000000000000000000000003287 144.0
SHD1_k127_678842_0 UDP binding domain K00012 - 1.1.1.22 3.194e-209 658.0
SHD1_k127_678842_1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 5.602e-197 621.0
SHD1_k127_678842_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 542.0
SHD1_k127_678842_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 513.0
SHD1_k127_678842_4 Capsule assembly protein Wzi - - - 0.00000000000002342 87.0
SHD1_k127_685341_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 2.723e-258 802.0
SHD1_k127_685341_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 484.0
SHD1_k127_685341_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 388.0
SHD1_k127_685341_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000003491 108.0
SHD1_k127_7157_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.787e-301 937.0
SHD1_k127_7157_1 PFAM Semialdehyde dehydrogenase NAD - binding K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 360.0
SHD1_k127_7157_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 336.0
SHD1_k127_7157_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000004709 258.0
SHD1_k127_7157_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K00950,K01633 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000004235 203.0
SHD1_k127_7157_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000009073 199.0
SHD1_k127_7157_6 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000001119 210.0
SHD1_k127_722876_0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 409.0
SHD1_k127_722876_1 KR domain K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 310.0
SHD1_k127_722876_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 308.0
SHD1_k127_722876_3 - - - - 0.00000000000000000000000000000000000000000000000000000006392 212.0
SHD1_k127_722876_4 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000007104 122.0
SHD1_k127_722876_5 - - - - 0.00000000000000000007179 91.0
SHD1_k127_722876_6 - - - - 0.00008354 49.0
SHD1_k127_725074_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 348.0
SHD1_k127_725074_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 323.0
SHD1_k127_725074_2 Aldehyde dehydrogenase family K00138 - - 0.0000000000000000000000000000000000000000000000000000002713 197.0
SHD1_k127_725938_0 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 614.0
SHD1_k127_725938_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 561.0
SHD1_k127_725938_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 505.0
SHD1_k127_725938_3 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 438.0
SHD1_k127_725938_4 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 350.0
SHD1_k127_725938_5 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 320.0
SHD1_k127_725938_6 YtxH-like protein - - - 0.0000000000000000000000000000000008135 139.0
SHD1_k127_728909_0 Peptidase family M1 domain - - - 1.777e-257 811.0
SHD1_k127_728909_1 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 439.0
SHD1_k127_728909_2 Aldo Keto reductase K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 293.0
SHD1_k127_736541_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.762e-275 850.0
SHD1_k127_736541_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 496.0
SHD1_k127_736541_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000003885 238.0
SHD1_k127_736541_3 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000008686 96.0
SHD1_k127_736541_4 PFAM PRC-barrel domain - - - 0.000000000000000001801 98.0
SHD1_k127_736541_5 - - - - 0.0000000000000006551 82.0
SHD1_k127_748096_0 SurA N-terminal domain K03770 - 5.2.1.8 2.044e-196 630.0
SHD1_k127_748096_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 559.0
SHD1_k127_748096_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 505.0
SHD1_k127_748096_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000000007291 226.0
SHD1_k127_748096_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000009106 179.0
SHD1_k127_748096_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000001116 168.0
SHD1_k127_760004_0 Sodium/hydrogen exchanger family K03316 - - 7.748e-201 639.0
SHD1_k127_760004_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 587.0
SHD1_k127_760004_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 513.0
SHD1_k127_760004_3 Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 428.0
SHD1_k127_760004_4 TIGRFAM endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000002287 149.0
SHD1_k127_760004_5 - - - - 0.00000000000000000000000000006958 118.0
SHD1_k127_760004_6 Belongs to the CinA family - - - 0.0000000000002658 78.0
SHD1_k127_770076_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 4.086e-228 723.0
SHD1_k127_770076_1 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 560.0
SHD1_k127_770076_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 456.0
SHD1_k127_770076_3 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 432.0
SHD1_k127_770076_4 rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009642 269.0
SHD1_k127_770076_5 rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000000000003712 183.0
SHD1_k127_770076_6 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000147 136.0
SHD1_k127_770076_7 Hsp70 protein K03569 - - 0.00000000000000000000000001596 109.0
SHD1_k127_783252_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 6.766e-283 899.0
SHD1_k127_783252_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 554.0
SHD1_k127_783252_2 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 482.0
SHD1_k127_783252_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 453.0
SHD1_k127_783252_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 - 6.2.1.5,6.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 448.0
SHD1_k127_783252_5 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00050,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 387.0
SHD1_k127_783252_6 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
SHD1_k127_783252_7 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000006545 241.0
SHD1_k127_783252_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000001262 167.0
SHD1_k127_783252_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000003546 157.0
SHD1_k127_803926_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000001719 202.0
SHD1_k127_803926_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000004392 164.0
SHD1_k127_803926_2 Protein of unknown function (DUF4235) - - - 0.00000004443 58.0
SHD1_k127_803926_3 arsenical-resistance protein K03325,K03741 - 1.20.4.1 0.0000007102 58.0
SHD1_k127_806984_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 611.0
SHD1_k127_806984_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 584.0
SHD1_k127_806984_2 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000015 165.0
SHD1_k127_821367_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 478.0
SHD1_k127_821367_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000006168 119.0
SHD1_k127_821367_2 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000002858 98.0
SHD1_k127_824493_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 9.171e-207 658.0
SHD1_k127_824493_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 554.0
SHD1_k127_824493_10 Zinc finger domain - - - 0.0000000000000000000000000006997 126.0
SHD1_k127_824493_11 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000003183 87.0
SHD1_k127_824493_12 Flavin reductase like domain - - - 0.00001512 48.0
SHD1_k127_824493_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 512.0
SHD1_k127_824493_3 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 450.0
SHD1_k127_824493_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 340.0
SHD1_k127_824493_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 300.0
SHD1_k127_824493_6 S4 RNA-binding domain K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 295.0
SHD1_k127_824493_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001317 274.0
SHD1_k127_824493_8 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000001347 137.0
SHD1_k127_824493_9 Segregation and condensation complex subunit ScpB - - - 0.000000000000000000000000000000006556 136.0
SHD1_k127_851536_0 TonB dependent receptor K16091 - - 2.815e-199 648.0
SHD1_k127_851536_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000004967 231.0
SHD1_k127_860422_0 Dehydrogenase K00114 - 1.1.2.8 1.219e-285 890.0
SHD1_k127_860422_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 2.119e-260 824.0
SHD1_k127_860422_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 330.0
SHD1_k127_860422_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 321.0
SHD1_k127_860422_4 cytochrome c oxidase, subunit III K02274,K02276,K15408 - 1.9.3.1 0.0000000000000000000000000000000000000008713 161.0
SHD1_k127_860422_5 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000002257 141.0
SHD1_k127_860422_6 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000003196 106.0
SHD1_k127_860422_7 - - - - 0.0002141 51.0
SHD1_k127_867018_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 416.0
SHD1_k127_867018_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 316.0
SHD1_k127_867018_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004217 274.0
SHD1_k127_867018_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000002531 179.0
SHD1_k127_867018_4 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000003644 110.0
SHD1_k127_867018_5 Cytochrome c assembly protein - - - 0.00000000000000513 81.0
SHD1_k127_867018_6 TonB C terminal K03832 - - 0.00000001183 61.0
SHD1_k127_881_0 Protein export membrane protein - - - 0.0 1540.0
SHD1_k127_881_1 LVIVD repeat - - - 2.965e-287 898.0
SHD1_k127_881_10 Biotin-lipoyl like - - - 0.000000000000000000000005637 104.0
SHD1_k127_881_11 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001592 101.0
SHD1_k127_881_12 - - - - 0.00000000000000000000006694 104.0
SHD1_k127_881_2 ABC transporter C-terminal domain K15738 - - 7.982e-259 812.0
SHD1_k127_881_3 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 578.0
SHD1_k127_881_4 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000008442 224.0
SHD1_k127_881_5 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000006336 143.0
SHD1_k127_881_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000005099 130.0
SHD1_k127_881_7 AI-2E family transporter - - - 0.00000000000000000000000000003182 124.0
SHD1_k127_881_8 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000002605 120.0
SHD1_k127_881_9 PFAM Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000003884 108.0
SHD1_k127_885407_0 IMP dehydrogenase activity K03281 - - 2.546e-244 769.0
SHD1_k127_885407_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 568.0
SHD1_k127_885407_2 FCD - - - 0.0000000000000000000000000000000000000001284 166.0
SHD1_k127_885407_3 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000001037 145.0
SHD1_k127_885407_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849,K12982 - - 0.0000000000000000000000000000002236 136.0
SHD1_k127_894480_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.661e-235 753.0
SHD1_k127_8958_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 310.0
SHD1_k127_8958_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001069 250.0
SHD1_k127_8958_2 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000002101 190.0
SHD1_k127_8958_3 Protein of unknown function (DUF541) K09807 - - 0.0000000000001669 80.0
SHD1_k127_8958_4 Putative heavy-metal-binding - - - 0.00001587 49.0
SHD1_k127_898306_0 Histidine kinase K01768,K02482,K02660,K03406,K05874,K07315,K10819,K11525,K11617 - 2.7.13.3,3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 493.0
SHD1_k127_898306_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 346.0
SHD1_k127_898306_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
SHD1_k127_898306_3 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002775 250.0
SHD1_k127_898306_4 COGs COG1125 ABC-type proline glycine betaine transport systems ATPase components K05847 - - 0.00000000000000000000000000000000000000000000000000000000000002138 226.0
SHD1_k127_898306_5 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000001647 201.0
SHD1_k127_898306_6 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000000006074 149.0
SHD1_k127_905450_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 408.0
SHD1_k127_905450_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000004171 185.0
SHD1_k127_905450_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000002294 73.0
SHD1_k127_905722_0 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 1.867e-289 900.0
SHD1_k127_905722_1 Type II/IV secretion system protein K02669 - - 5.644e-194 613.0
SHD1_k127_905722_10 chitin binding K01183 - 3.2.1.14 0.000000000000000000000000004845 128.0
SHD1_k127_905722_11 Peptidase M28 - - - 0.00000000000000000000008364 101.0
SHD1_k127_905722_12 PRC-barrel domain - - - 0.0000000000000000000001439 109.0
SHD1_k127_905722_13 - - - - 0.000000000000000000001675 109.0
SHD1_k127_905722_15 Domain of unknown function (DUF378) K09779 - - 0.000000000000000002437 90.0
SHD1_k127_905722_16 Helix-hairpin-helix motif K02237 - - 0.00000000000005742 81.0
SHD1_k127_905722_17 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000004585 79.0
SHD1_k127_905722_18 Domain of unknown function (DUF2382) - - - 0.000000000009199 76.0
SHD1_k127_905722_19 - - - - 0.00000001671 68.0
SHD1_k127_905722_2 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 586.0
SHD1_k127_905722_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 552.0
SHD1_k127_905722_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 496.0
SHD1_k127_905722_5 metallopeptidase activity K06402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 412.0
SHD1_k127_905722_6 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001565 287.0
SHD1_k127_905722_7 - - - - 0.000000000000000000000000000000000000000000000000000000000001382 221.0
SHD1_k127_905722_8 helix_turn_helix, mercury resistance K22491 - - 0.0000000000000000000000000000000000000000000000000223 191.0
SHD1_k127_905722_9 Transglycosylase associated protein - - - 0.0000000000000000000000000001411 119.0
SHD1_k127_90943_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 473.0
SHD1_k127_90943_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 364.0
SHD1_k127_90943_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000002735 145.0
SHD1_k127_90943_11 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000007754 138.0
SHD1_k127_90943_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000005782 101.0
SHD1_k127_90943_13 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000001069 53.0
SHD1_k127_90943_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 314.0
SHD1_k127_90943_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000001118 239.0
SHD1_k127_90943_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000001933 227.0
SHD1_k127_90943_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000002735 203.0
SHD1_k127_90943_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000002745 168.0
SHD1_k127_90943_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000001885 164.0
SHD1_k127_90943_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000005329 154.0
SHD1_k127_90943_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000001043 154.0
SHD1_k127_909490_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1114.0
SHD1_k127_909490_1 Amidohydrolase family - - - 8.517e-254 793.0
SHD1_k127_909490_2 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000000000000005151 215.0
SHD1_k127_909490_3 HNH nucleases - - - 0.000000000000000000000000000000000000000001006 159.0
SHD1_k127_909490_4 - - - - 0.000000000000000000000000005588 113.0
SHD1_k127_909656_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 2.707e-261 823.0
SHD1_k127_909656_1 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000003364 235.0
SHD1_k127_909656_2 - - - - 0.0000000000000000000000000000000000000000001295 168.0
SHD1_k127_909656_3 Tfp pilus assembly protein FimV - - - 0.0001963 51.0
SHD1_k127_913478_0 COG0433 Predicted ATPase K06915 - - 1.513e-270 842.0
SHD1_k127_913478_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 486.0
SHD1_k127_913478_2 AAA domain K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 336.0
SHD1_k127_913478_3 - - - - 0.0000000000000000000000000009682 126.0
SHD1_k127_923275_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 537.0
SHD1_k127_923275_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 381.0
SHD1_k127_923275_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 338.0
SHD1_k127_923275_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 339.0
SHD1_k127_923275_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 324.0
SHD1_k127_923275_5 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000001879 233.0
SHD1_k127_923275_6 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000007027 186.0
SHD1_k127_923275_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000001471 84.0
SHD1_k127_930135_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 555.0
SHD1_k127_930135_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 333.0
SHD1_k127_930135_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009784 278.0
SHD1_k127_938073_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 509.0
SHD1_k127_938073_1 hydrolase activity, acting on ester bonds K07017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008483 280.0
SHD1_k127_938073_2 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000000000002628 237.0
SHD1_k127_938073_3 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000001418 185.0
SHD1_k127_938073_4 Cupin domain - - - 0.00000000000000000000000000000000000001146 149.0
SHD1_k127_938073_5 GYD domain - - - 0.000000000000000000000000000000012 130.0
SHD1_k127_938073_6 DinB family - - - 0.0000000000000000000003465 104.0
SHD1_k127_941339_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 622.0
SHD1_k127_941339_1 Lysin motif - - - 0.00000000000000000004487 103.0
SHD1_k127_942638_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 3.78e-277 863.0
SHD1_k127_942638_1 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 344.0
SHD1_k127_942638_2 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 323.0
SHD1_k127_942638_3 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 293.0
SHD1_k127_942638_4 Transcriptional regulator K07669 - - 0.0000000000000000000000000000000000000000000000000000000000000000003504 237.0
SHD1_k127_942638_5 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000003006 230.0
SHD1_k127_942638_6 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000000000000000000000003095 227.0
SHD1_k127_942638_7 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000001032 145.0
SHD1_k127_942638_8 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000006609 141.0
SHD1_k127_947745_0 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 437.0
SHD1_k127_947745_1 Part of SUF system involved in inserting iron-sulfur clusters into proteins K09013 - - 0.00000000000000000000000000000001163 127.0
SHD1_k127_947745_2 histone H2A K63-linked ubiquitination - - - 0.0008535 47.0
SHD1_k127_956356_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 581.0
SHD1_k127_956356_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000004622 208.0
SHD1_k127_960395_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.26e-271 845.0
SHD1_k127_960395_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 7.819e-246 766.0
SHD1_k127_960395_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 379.0
SHD1_k127_960395_3 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000003421 203.0
SHD1_k127_960395_4 NUDIX domain - - - 0.0000000000000000000000000000000000000000001184 161.0
SHD1_k127_960395_5 - - - - 0.0000000000000000000000000000000003532 142.0
SHD1_k127_960395_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000006993 118.0
SHD1_k127_963992_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.311e-249 788.0
SHD1_k127_963992_1 von Willebrand factor (vWF) type A domain - - - 9.274e-226 705.0
SHD1_k127_963992_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 381.0
SHD1_k127_963992_3 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 359.0
SHD1_k127_963992_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000004458 116.0
SHD1_k127_965432_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 479.0
SHD1_k127_965432_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 316.0
SHD1_k127_965432_2 HEAT repeats - - - 0.00000000002466 66.0
SHD1_k127_968044_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 304.0
SHD1_k127_968044_1 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 300.0
SHD1_k127_968044_2 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001136 269.0
SHD1_k127_968044_3 Transport permease protein - - - 0.00000000000000000000000003108 118.0
SHD1_k127_971085_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 3.14e-268 845.0
SHD1_k127_971085_1 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 2.205e-239 756.0
SHD1_k127_971085_10 - - - - 0.000000000001575 76.0
SHD1_k127_971085_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 484.0
SHD1_k127_971085_3 Methyltransferase small domain K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 323.0
SHD1_k127_971085_4 PFAM Cytochrome C oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 301.0
SHD1_k127_971085_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000002396 208.0
SHD1_k127_971085_6 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K15408 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000005728 192.0
SHD1_k127_971085_7 Control of competence regulator ComK, YlbF/YmcA - - - 0.0000000000000000000000000000000000005666 149.0
SHD1_k127_971085_8 cytochrome c K00406 - - 0.000000000000000000000000000003421 139.0
SHD1_k127_971085_9 Binds the 23S rRNA K02909 - - 0.0000000000000000000000001887 108.0
SHD1_k127_981922_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 317.0
SHD1_k127_981922_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000245 280.0
SHD1_k127_981922_2 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000005752 234.0
SHD1_k127_981922_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000004623 211.0
SHD1_k127_983487_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 1.515e-238 767.0
SHD1_k127_990548_0 ACT domain K12524 - 1.1.1.3,2.7.2.4 4.338e-269 852.0
SHD1_k127_990548_1 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 478.0
SHD1_k127_990548_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000006898 233.0
SHD1_k127_990548_3 Squalene--hopene cyclase - - - 0.000000000000000000000000000000000000000000003652 173.0
SHD1_k127_990548_4 -acetyltransferase - - - 0.0000000000000000000000000000001559 131.0
SHD1_k127_990548_5 protein kinase activity - - - 0.00000000000000000000002447 106.0
SHD1_k127_993174_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.08e-205 662.0
SHD1_k127_993174_1 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 452.0
SHD1_k127_993174_2 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 437.0
SHD1_k127_993174_3 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 395.0
SHD1_k127_993174_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000004864 251.0
SHD1_k127_993174_6 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000132 112.0