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Overview

ID MAG03564
Name SRD2_bin.18
Sample SMP0089
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Sphingomonadales
Family Sphingomonadaceae
Genus Sphingomicrobium
Species
Assembly information
Completeness (%) 88.18
Contamination (%) 6.35
GC content (%) 63.0
N50 (bp) 23,879
Genome size (bp) 2,236,882

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2121

Gene name Description KEGG GOs EC E-value Score Sequence
SRD2_k127_1115443_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2546.0
SRD2_k127_1115443_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 470.0
SRD2_k127_1115443_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000008108 62.0
SRD2_k127_1115443_5 TonB-dependent Receptor Plug Domain K02014 - - 0.000004367 48.0
SRD2_k127_1516045_0 COG1505 Serine proteases of the peptidase family S9A K01322 - 3.4.21.26 1.008e-293 918.0
SRD2_k127_1516045_1 Sugar (and other) transporter K08369 - - 2.661e-229 722.0
SRD2_k127_1516045_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 7.052e-224 720.0
SRD2_k127_1516045_3 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 555.0
SRD2_k127_1516045_4 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 500.0
SRD2_k127_1516045_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 355.0
SRD2_k127_1516045_6 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 351.0
SRD2_k127_1516045_7 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002007 264.0
SRD2_k127_1516045_8 filamentation induced by cAMP protein Fic - - - 0.0000000000000000000000000000000000000000000000000005593 185.0
SRD2_k127_1516045_9 - - - - 0.0000000005082 72.0
SRD2_k127_1574262_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1761.0
SRD2_k127_1574262_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1466.0
SRD2_k127_1574262_10 RNB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 544.0
SRD2_k127_1574262_11 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 529.0
SRD2_k127_1574262_12 Reductase C-terminal K05297 - 1.18.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 509.0
SRD2_k127_1574262_13 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 492.0
SRD2_k127_1574262_14 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 435.0
SRD2_k127_1574262_15 Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 444.0
SRD2_k127_1574262_16 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 355.0
SRD2_k127_1574262_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 351.0
SRD2_k127_1574262_18 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 340.0
SRD2_k127_1574262_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 323.0
SRD2_k127_1574262_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1406.0
SRD2_k127_1574262_20 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 306.0
SRD2_k127_1574262_21 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002471 278.0
SRD2_k127_1574262_22 amino acid aldolase or racemase K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
SRD2_k127_1574262_23 Cell Wall Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009107 253.0
SRD2_k127_1574262_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001489 240.0
SRD2_k127_1574262_25 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001611 239.0
SRD2_k127_1574262_26 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000001954 231.0
SRD2_k127_1574262_27 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000000000001783 220.0
SRD2_k127_1574262_28 COG0739 Membrane proteins related to metalloendopeptidases K21472 - - 0.00000000000000000000000000000000000000000000000000000001114 205.0
SRD2_k127_1574262_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000006385 196.0
SRD2_k127_1574262_3 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 5e-324 1002.0
SRD2_k127_1574262_30 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000005836 189.0
SRD2_k127_1574262_31 - - - - 0.0000000000000000000000000000000000000000000000000006054 185.0
SRD2_k127_1574262_32 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000002851 189.0
SRD2_k127_1574262_33 helix_turn_helix, mercury resistance K08365 - - 0.0000000000000000000000000000000000000000000000152 177.0
SRD2_k127_1574262_34 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000005665 169.0
SRD2_k127_1574262_35 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000007297 130.0
SRD2_k127_1574262_36 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000000000000007475 127.0
SRD2_k127_1574262_37 amino acid aldolase or racemase K20757 - 4.3.1.27 0.000000000000000000000000000001973 125.0
SRD2_k127_1574262_38 Protein of unknown function (DUF2842) - - - 0.0000000000000000003826 90.0
SRD2_k127_1574262_39 - - - - 0.0000000000005755 71.0
SRD2_k127_1574262_4 Glycosyl hydrolases family 31 K01187 - 3.2.1.20 1.507e-320 997.0
SRD2_k127_1574262_41 COG2214 DnaJ-class molecular chaperone - - - 0.0000004329 61.0
SRD2_k127_1574262_5 Belongs to the transketolase family K00615 - 2.2.1.1 1.251e-316 981.0
SRD2_k127_1574262_6 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 7.731e-209 670.0
SRD2_k127_1574262_7 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 9.186e-200 631.0
SRD2_k127_1574262_8 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 599.0
SRD2_k127_1574262_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 576.0
SRD2_k127_1580481_0 peptidase S9 K01354 - 3.4.21.83 0.0 1019.0
SRD2_k127_1580481_1 aminopeptidase K01262 - 3.4.11.9 1.329e-296 919.0
SRD2_k127_1580481_10 Winged helix DNA-binding domain - - - 0.000000000000000000000000203 115.0
SRD2_k127_1580481_11 Periplasmic Protein - - - 0.000000000000000000000002794 111.0
SRD2_k127_1580481_12 - - - - 0.0000000000000000000471 95.0
SRD2_k127_1580481_14 KTSC domain - - - 0.00000000001729 66.0
SRD2_k127_1580481_16 PFAM blue (type 1) copper domain protein - - - 0.000007225 49.0
SRD2_k127_1580481_2 Putative diguanylate phosphodiesterase - - - 2.807e-203 657.0
SRD2_k127_1580481_3 Dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 494.0
SRD2_k127_1580481_4 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 471.0
SRD2_k127_1580481_5 Aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 451.0
SRD2_k127_1580481_6 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 329.0
SRD2_k127_1580481_7 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 290.0
SRD2_k127_1580481_8 thioesterase K07107 - - 0.00000000000000000000000000000000000000000000000007567 184.0
SRD2_k127_1580481_9 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000003065 177.0
SRD2_k127_1654438_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1322.0
SRD2_k127_1654438_1 Transport of potassium into the cell K03549 - - 6.786e-302 938.0
SRD2_k127_1654438_10 cyclic nucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 303.0
SRD2_k127_1654438_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000003989 254.0
SRD2_k127_1654438_12 COG1073 hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
SRD2_k127_1654438_13 - - - - 0.000000000000000000000000000000000000000000000000000000000003813 219.0
SRD2_k127_1654438_14 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001208 201.0
SRD2_k127_1654438_15 Alkyl hydroperoxide reductase K02199 - - 0.0000000000000000000000000000000000000000000000000125 185.0
SRD2_k127_1654438_16 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000000000001548 186.0
SRD2_k127_1654438_17 Protein of unknown function (DUF3775) - - - 0.00000000000000000000000000000000000000000000000989 176.0
SRD2_k127_1654438_18 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000001526 171.0
SRD2_k127_1654438_19 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000001409 169.0
SRD2_k127_1654438_2 peptidase M13 K07386 - - 3.412e-292 914.0
SRD2_k127_1654438_20 Cytochrome c biogenesis factor K02200 - - 0.0000000000000000000000000000000000000000001331 171.0
SRD2_k127_1654438_21 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001776 154.0
SRD2_k127_1654438_22 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000002921 138.0
SRD2_k127_1654438_3 Histidine kinase K13587 - 2.7.13.3 9.585e-266 840.0
SRD2_k127_1654438_4 cytochrome C K02198 - - 2.077e-259 814.0
SRD2_k127_1654438_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 8.403e-246 762.0
SRD2_k127_1654438_6 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 5.932e-204 638.0
SRD2_k127_1654438_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 483.0
SRD2_k127_1654438_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 370.0
SRD2_k127_1654438_9 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 346.0
SRD2_k127_1752646_0 protein conserved in bacteria K09800 - - 0.0 1356.0
SRD2_k127_1752646_1 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 3.415e-275 849.0
SRD2_k127_1752646_10 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 339.0
SRD2_k127_1752646_11 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 332.0
SRD2_k127_1752646_12 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 316.0
SRD2_k127_1752646_13 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
SRD2_k127_1752646_14 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002433 247.0
SRD2_k127_1752646_15 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000003126 219.0
SRD2_k127_1752646_16 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000008439 210.0
SRD2_k127_1752646_17 - - - - 0.000000000000000000005429 93.0
SRD2_k127_1752646_18 - - - - 0.000000000000000000009566 95.0
SRD2_k127_1752646_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 3.198e-247 775.0
SRD2_k127_1752646_3 amino acid K03294 - - 8.326e-218 685.0
SRD2_k127_1752646_4 de-polymerase K05973 - 3.1.1.75 1.22e-201 633.0
SRD2_k127_1752646_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 1.91e-201 632.0
SRD2_k127_1752646_6 COG0729 Outer membrane protein K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 605.0
SRD2_k127_1752646_7 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 550.0
SRD2_k127_1752646_8 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 454.0
SRD2_k127_1752646_9 DNA topoisomerase K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 436.0
SRD2_k127_1815017_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 9.917e-257 804.0
SRD2_k127_1815017_1 Penicillin-binding Protein K05515 - 3.4.16.4 6.64e-239 760.0
SRD2_k127_1815017_10 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000004263 152.0
SRD2_k127_1815017_11 rod shape-determining protein MreB K03569 - - 0.00000000000000000000000000007119 115.0
SRD2_k127_1815017_2 rod shape-determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 549.0
SRD2_k127_1815017_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 503.0
SRD2_k127_1815017_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 381.0
SRD2_k127_1815017_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 356.0
SRD2_k127_1815017_6 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 346.0
SRD2_k127_1815017_7 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 311.0
SRD2_k127_1815017_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 312.0
SRD2_k127_1815017_9 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000299 208.0
SRD2_k127_182803_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1523.0
SRD2_k127_182803_1 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1251.0
SRD2_k127_182803_10 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 543.0
SRD2_k127_182803_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 526.0
SRD2_k127_182803_12 Na -driven multidrug efflux pump K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 479.0
SRD2_k127_182803_13 Methionine synthase I (cobalamin-dependent), methyltransferase domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 475.0
SRD2_k127_182803_14 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 461.0
SRD2_k127_182803_15 In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 449.0
SRD2_k127_182803_16 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 447.0
SRD2_k127_182803_17 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 427.0
SRD2_k127_182803_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 402.0
SRD2_k127_182803_19 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 398.0
SRD2_k127_182803_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 7.817e-320 1005.0
SRD2_k127_182803_20 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 388.0
SRD2_k127_182803_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 366.0
SRD2_k127_182803_22 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 350.0
SRD2_k127_182803_23 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003056 288.0
SRD2_k127_182803_24 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000000000000000003981 223.0
SRD2_k127_182803_25 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000002852 203.0
SRD2_k127_182803_26 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000002493 206.0
SRD2_k127_182803_27 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000001398 182.0
SRD2_k127_182803_28 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000006556 174.0
SRD2_k127_182803_29 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000002243 121.0
SRD2_k127_182803_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.243e-308 948.0
SRD2_k127_182803_30 protein secretion K03116 - - 0.000000000000000001321 89.0
SRD2_k127_182803_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 3.891e-234 730.0
SRD2_k127_182803_5 peptidase S10 serine carboxypeptidase - - - 1.618e-215 683.0
SRD2_k127_182803_6 signal peptide peptidase K04773 - - 6.327e-208 663.0
SRD2_k127_182803_7 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 603.0
SRD2_k127_182803_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 564.0
SRD2_k127_182803_9 AFG1 family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 528.0
SRD2_k127_1988029_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 512.0
SRD2_k127_1988029_1 nitrogen fixation sensor protein fixL K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 437.0
SRD2_k127_1988029_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 346.0
SRD2_k127_1988029_3 part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes K14987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003238 273.0
SRD2_k127_1988029_4 CRP FNR family K01420 - - 0.00000000000000000000000000000000000000000000000000000000000001289 226.0
SRD2_k127_1988029_5 Belongs to the small heat shock protein (HSP20) family K13993 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006457,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0033554,GO:0034605,GO:0034620,GO:0035966,GO:0035967,GO:0042221,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0050896,GO:0051082,GO:0051716,GO:0051788,GO:0061077,GO:0070887,GO:0071218,GO:0071310 - 0.00000000000000000000000000000000003337 141.0
SRD2_k127_1988029_6 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000002358 134.0
SRD2_k127_1988029_7 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000003006 119.0
SRD2_k127_1988029_8 - - - - 0.0000000000000000000000002353 109.0
SRD2_k127_1991030_0 Tryptophan halogenase K14266 - 1.14.19.9 2.708e-233 743.0
SRD2_k127_1991030_1 Aldehyde dehydrogenase family - - - 9.464e-196 623.0
SRD2_k127_1991030_2 Glycosyl hydrolase family 3 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 564.0
SRD2_k127_1991030_3 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 484.0
SRD2_k127_1991030_4 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 401.0
SRD2_k127_1991030_5 Major Facilitator Superfamily K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 376.0
SRD2_k127_1991030_6 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 372.0
SRD2_k127_1991030_7 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 320.0
SRD2_k127_1991030_8 Glycosyl hydrolases family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 307.0
SRD2_k127_1991030_9 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000004207 133.0
SRD2_k127_2008840_0 Thi4 family - - - 1.036e-265 825.0
SRD2_k127_2008840_1 oligosaccharyl transferase activity - - - 1.213e-221 702.0
SRD2_k127_2008840_10 methyltransferase K05928 - 2.1.1.95 0.00000000000000000000007731 111.0
SRD2_k127_2008840_11 Protein conserved in bacteria - - - 0.000000000000000002139 87.0
SRD2_k127_2008840_2 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 562.0
SRD2_k127_2008840_3 Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 503.0
SRD2_k127_2008840_4 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 496.0
SRD2_k127_2008840_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 404.0
SRD2_k127_2008840_6 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 391.0
SRD2_k127_2008840_7 UPF0056 membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001114 260.0
SRD2_k127_2008840_8 GtrA-like protein - - - 0.00000000000000000000000000000000000004051 163.0
SRD2_k127_2008840_9 GtrA-like protein - - - 0.000000000000000000000000001407 117.0
SRD2_k127_2024815_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1380.0
SRD2_k127_2024815_1 DNA polymerase K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 2.014e-319 1021.0
SRD2_k127_2024815_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 328.0
SRD2_k127_2024815_11 amine dehydrogenase activity K17285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 298.0
SRD2_k127_2024815_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005713 253.0
SRD2_k127_2024815_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000004211 222.0
SRD2_k127_2024815_15 protein conserved in bacteria K21470 - - 0.0000000000000000000000000000000000000000000000000000000000001046 222.0
SRD2_k127_2024815_16 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000002161 197.0
SRD2_k127_2024815_17 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000001019 182.0
SRD2_k127_2024815_18 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000001836 186.0
SRD2_k127_2024815_19 - - - - 0.0000000008953 68.0
SRD2_k127_2024815_2 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 2.41e-238 740.0
SRD2_k127_2024815_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.187e-225 708.0
SRD2_k127_2024815_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 9.824e-217 688.0
SRD2_k127_2024815_5 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 605.0
SRD2_k127_2024815_6 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 499.0
SRD2_k127_2024815_7 cystathionine beta-lyase K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 485.0
SRD2_k127_2024815_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 386.0
SRD2_k127_2024815_9 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 357.0
SRD2_k127_2067183_0 In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 447.0
SRD2_k127_2067183_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 444.0
SRD2_k127_2067183_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 370.0
SRD2_k127_2135818_0 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 2.369e-220 698.0
SRD2_k127_2135818_1 Aerobic cobaltochelatase subunit CobS K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 601.0
SRD2_k127_2135818_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008301 248.0
SRD2_k127_2135818_11 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001975 233.0
SRD2_k127_2135818_12 Lactoylglutathione lyase K07032 - - 0.000000000000000000000000000000000000000000000000000007168 195.0
SRD2_k127_2135818_13 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000000000004417 170.0
SRD2_k127_2135818_14 DoxX-like family - - - 0.0000000000000000000000000000000002799 136.0
SRD2_k127_2135818_15 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000000001021 122.0
SRD2_k127_2135818_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 414.0
SRD2_k127_2135818_3 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 293.0
SRD2_k127_2135818_4 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 282.0
SRD2_k127_2135818_5 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001677 271.0
SRD2_k127_2135818_6 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002273 267.0
SRD2_k127_2135818_7 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000009681 267.0
SRD2_k127_2135818_8 molecular chaperone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008862 258.0
SRD2_k127_2135818_9 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000001631 253.0
SRD2_k127_2141181_0 X-Pro dipeptidyl-peptidase domain protein - - - 1.348e-265 832.0
SRD2_k127_2141181_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 9.561e-253 785.0
SRD2_k127_2141181_10 PilZ domain - - - 0.0001226 49.0
SRD2_k127_2141181_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 552.0
SRD2_k127_2141181_3 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 353.0
SRD2_k127_2141181_4 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 350.0
SRD2_k127_2141181_5 Domain of unknown function (DUF4118) - - - 0.00000000000000000000000000000000000000000000000000000000001043 217.0
SRD2_k127_2141181_6 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000005491 192.0
SRD2_k127_2141181_7 - - - - 0.00000000000000000000000000002248 124.0
SRD2_k127_2141181_8 Protein of unknown function (DUF1778) - - - 0.000000000000000000006128 96.0
SRD2_k127_2155545_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.619e-231 728.0
SRD2_k127_2155545_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 6.315e-222 700.0
SRD2_k127_2155545_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000001 245.0
SRD2_k127_2155545_11 membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000001759 232.0
SRD2_k127_2155545_12 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000000065 211.0
SRD2_k127_2155545_13 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000001925 134.0
SRD2_k127_2155545_14 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000002751 118.0
SRD2_k127_2155545_15 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000011 114.0
SRD2_k127_2155545_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 582.0
SRD2_k127_2155545_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 487.0
SRD2_k127_2155545_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 407.0
SRD2_k127_2155545_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 385.0
SRD2_k127_2155545_6 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 337.0
SRD2_k127_2155545_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 284.0
SRD2_k127_2155545_8 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002842 261.0
SRD2_k127_2155545_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002081 256.0
SRD2_k127_2191120_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1167.0
SRD2_k127_2191120_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1068.0
SRD2_k127_2191120_10 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 383.0
SRD2_k127_2191120_11 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 370.0
SRD2_k127_2191120_12 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 353.0
SRD2_k127_2191120_13 Cytochrome C oxidase subunit II, periplasmic domain K02297 - 1.10.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 343.0
SRD2_k127_2191120_14 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 342.0
SRD2_k127_2191120_15 Protein of unknown function (DUF3667) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 320.0
SRD2_k127_2191120_16 beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 312.0
SRD2_k127_2191120_17 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 291.0
SRD2_k127_2191120_18 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006578 294.0
SRD2_k127_2191120_19 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005715 272.0
SRD2_k127_2191120_2 Belongs to the heme-copper respiratory oxidase family K02298 - 1.10.3.10 4.25e-305 949.0
SRD2_k127_2191120_20 glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 267.0
SRD2_k127_2191120_21 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000237 271.0
SRD2_k127_2191120_22 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004237 252.0
SRD2_k127_2191120_23 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003899 255.0
SRD2_k127_2191120_24 CytOchrome o ubiquinol oxidase K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000005868 250.0
SRD2_k127_2191120_25 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002077 249.0
SRD2_k127_2191120_26 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000003424 244.0
SRD2_k127_2191120_27 Domain of unknown function (DUF4115) - - - 0.00000000000000000000000000000000000000000000000000000000000000009766 231.0
SRD2_k127_2191120_28 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000221 212.0
SRD2_k127_2191120_29 Membrane-bound metallopeptidase - - - 0.00000000000000000000000000000000000000000000000000005591 201.0
SRD2_k127_2191120_3 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 4.176e-218 688.0
SRD2_k127_2191120_30 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000005499 186.0
SRD2_k127_2191120_31 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000003569 187.0
SRD2_k127_2191120_32 Disulfide bond formation protein - - - 0.0000000000000000000000000000000000000000000001991 173.0
SRD2_k127_2191120_33 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000001454 162.0
SRD2_k127_2191120_34 Prokaryotic Cytochrome C oxidase subunit IV K02300 - - 0.0000000000000000000000000000000000004833 153.0
SRD2_k127_2191120_36 - - - - 0.0000000000000000000000000000047 123.0
SRD2_k127_2191120_37 - - - - 0.00000000000000000000002888 105.0
SRD2_k127_2191120_38 - - - - 0.000000000000000000363 90.0
SRD2_k127_2191120_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.302e-203 640.0
SRD2_k127_2191120_5 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 567.0
SRD2_k127_2191120_6 Putative esterase K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 429.0
SRD2_k127_2191120_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 430.0
SRD2_k127_2191120_8 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 415.0
SRD2_k127_2191120_9 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 408.0
SRD2_k127_2329380_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1427.0
SRD2_k127_2329380_1 Sulfotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 599.0
SRD2_k127_2329380_2 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 571.0
SRD2_k127_2329380_3 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 420.0
SRD2_k127_2329380_4 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 350.0
SRD2_k127_2329380_5 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 325.0
SRD2_k127_2329380_6 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005387 247.0
SRD2_k127_2329380_7 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.0000000000000000000000002727 108.0
SRD2_k127_2329380_8 - - - - 0.000009178 50.0
SRD2_k127_2329380_9 Histidine kinase-like ATPases - - - 0.0008195 42.0
SRD2_k127_2335681_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1416.0
SRD2_k127_2335681_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 1.14e-224 704.0
SRD2_k127_2335681_10 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008668 239.0
SRD2_k127_2335681_11 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000000009155 235.0
SRD2_k127_2335681_12 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000000000000000000000001555 214.0
SRD2_k127_2335681_13 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000001811 200.0
SRD2_k127_2335681_14 Septum formation initiator - - - 0.0000000000000000000000000000000001306 135.0
SRD2_k127_2335681_15 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000002437 135.0
SRD2_k127_2335681_16 Domain of unknown function (DUF4170) - - - 0.0000000000000000000000000000002695 124.0
SRD2_k127_2335681_17 - - - - 0.00000000000000000000000000002857 124.0
SRD2_k127_2335681_18 Tetratricopeptide repeat - - - 0.00000000000000000000000000005081 131.0
SRD2_k127_2335681_19 - - - - 0.00000000000003597 81.0
SRD2_k127_2335681_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.235e-218 686.0
SRD2_k127_2335681_20 Domain of unknown function (DUF4142) K08995 - - 0.000000000001934 75.0
SRD2_k127_2335681_21 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000005093 59.0
SRD2_k127_2335681_22 Protein of unknown function (DUF3618) - - - 0.00000008392 61.0
SRD2_k127_2335681_23 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000003452 52.0
SRD2_k127_2335681_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 7.43e-218 686.0
SRD2_k127_2335681_4 DNA repair photolyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 578.0
SRD2_k127_2335681_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 565.0
SRD2_k127_2335681_6 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 479.0
SRD2_k127_2335681_7 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 334.0
SRD2_k127_2335681_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 320.0
SRD2_k127_2335681_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007127 248.0
SRD2_k127_2343257_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.246e-307 949.0
SRD2_k127_2343257_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.276e-225 704.0
SRD2_k127_2343257_2 Hpt domain K20976 - - 0.0000000000000000000000000000000000000000000000000000000000005426 215.0
SRD2_k127_2589820_0 Ferrous iron transport protein B K04759 - - 1.472e-275 861.0
SRD2_k127_2589820_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.574e-219 686.0
SRD2_k127_2589820_10 Fe2 transport system protein A K04758 - - 0.000000000000000000000000006911 111.0
SRD2_k127_2589820_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 384.0
SRD2_k127_2589820_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 337.0
SRD2_k127_2589820_4 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008232 267.0
SRD2_k127_2589820_5 RpsU-divergently transcribed K18587 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003366 257.0
SRD2_k127_2589820_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000006552 214.0
SRD2_k127_2589820_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000002687 196.0
SRD2_k127_2589820_8 Uncharacterized ACR, COG1399 - - - 0.000000000000000000000000000000000000000000000000000007174 194.0
SRD2_k127_2589820_9 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000000000000000002704 140.0
SRD2_k127_2615919_0 Histidine kinase - - - 4.154e-221 705.0
SRD2_k127_2615919_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 1.408e-202 636.0
SRD2_k127_2615919_10 chemotaxis protein K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000497 274.0
SRD2_k127_2615919_11 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000007794 241.0
SRD2_k127_2615919_12 lipocalin K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000001353 229.0
SRD2_k127_2615919_13 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000002278 211.0
SRD2_k127_2615919_14 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000005122 201.0
SRD2_k127_2615919_15 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000008455 182.0
SRD2_k127_2615919_16 Cupin domain - - - 0.00000000000000000000000000000000000001896 149.0
SRD2_k127_2615919_17 membrane - - - 0.00000000000000000000000000000004118 134.0
SRD2_k127_2615919_18 Predicted membrane protein (DUF2306) - - - 0.000000000000000000003955 103.0
SRD2_k127_2615919_19 SnoaL-like domain - - - 0.000000000001366 79.0
SRD2_k127_2615919_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 547.0
SRD2_k127_2615919_20 TonB-dependent receptor K16092 - - 0.0000000000695 72.0
SRD2_k127_2615919_21 - - - - 0.0000000002302 63.0
SRD2_k127_2615919_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 545.0
SRD2_k127_2615919_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 443.0
SRD2_k127_2615919_5 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 404.0
SRD2_k127_2615919_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 385.0
SRD2_k127_2615919_7 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 330.0
SRD2_k127_2615919_8 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 360.0
SRD2_k127_2615919_9 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 300.0
SRD2_k127_2642215_0 Acetyl-coenzyme A transporter 1 K08218 - - 1.024e-215 685.0
SRD2_k127_2642215_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 513.0
SRD2_k127_2642215_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 451.0
SRD2_k127_2642215_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 344.0
SRD2_k127_2642215_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 289.0
SRD2_k127_2642215_5 beta-lactamase K01467 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000005029 208.0
SRD2_k127_2642215_6 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000007826 194.0
SRD2_k127_2642215_7 response regulator - - - 0.000000000000000000000000000000000000002552 151.0
SRD2_k127_2642215_8 Pfam:DUF1049 K08992 - - 0.0000000000000000000006581 100.0
SRD2_k127_2651902_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0 1085.0
SRD2_k127_2651902_1 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.0 1041.0
SRD2_k127_2651902_10 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 512.0
SRD2_k127_2651902_11 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 404.0
SRD2_k127_2651902_12 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 389.0
SRD2_k127_2651902_13 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 379.0
SRD2_k127_2651902_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 306.0
SRD2_k127_2651902_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000002253 255.0
SRD2_k127_2651902_16 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001837 246.0
SRD2_k127_2651902_17 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003938 249.0
SRD2_k127_2651902_18 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000000009409 241.0
SRD2_k127_2651902_19 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001205 237.0
SRD2_k127_2651902_2 acyl-CoA dehydrogenase - - - 1.596e-268 837.0
SRD2_k127_2651902_20 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000000000000000000002299 200.0
SRD2_k127_2651902_21 - - - - 0.0000000000000000000000000000000000000000000000000001276 193.0
SRD2_k127_2651902_22 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000001379 192.0
SRD2_k127_2651902_23 DoxX - - - 0.0000000000000000000000000000000000000003279 163.0
SRD2_k127_2651902_24 - - - - 0.000000000000000000001933 98.0
SRD2_k127_2651902_25 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000002325 100.0
SRD2_k127_2651902_26 - - - - 0.000000000000000000002526 96.0
SRD2_k127_2651902_29 TIR domain - - - 0.0000008589 60.0
SRD2_k127_2651902_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.632e-256 799.0
SRD2_k127_2651902_4 Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) K01484 - 3.5.3.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 602.0
SRD2_k127_2651902_5 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 601.0
SRD2_k127_2651902_6 synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 575.0
SRD2_k127_2651902_7 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 572.0
SRD2_k127_2651902_8 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 514.0
SRD2_k127_2651902_9 arginine N-succinyltransferase K00673 - 2.3.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 511.0
SRD2_k127_2672568_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1083.0
SRD2_k127_2672568_1 Glucose dehydrogenase K00117 - 1.1.5.2 0.0 1052.0
SRD2_k127_2672568_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 381.0
SRD2_k127_2672568_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 376.0
SRD2_k127_2672568_12 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 343.0
SRD2_k127_2672568_13 GcrA cell cycle regulator K13583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 323.0
SRD2_k127_2672568_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002049 281.0
SRD2_k127_2672568_15 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009989 273.0
SRD2_k127_2672568_16 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000001849 253.0
SRD2_k127_2672568_17 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000003447 222.0
SRD2_k127_2672568_18 Fatty acid desaturase K00496 - 1.14.15.3 0.000000000000000000000000000000000000000000000000000000004408 212.0
SRD2_k127_2672568_19 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.00000000000000000000000000000000000000000000000000000001437 205.0
SRD2_k127_2672568_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.884e-229 715.0
SRD2_k127_2672568_20 Transcriptional regulator - - - 0.0000000000000000000000000000000001291 154.0
SRD2_k127_2672568_21 - - - - 0.0000000000000000002299 94.0
SRD2_k127_2672568_22 - - - - 0.00000000000000001231 89.0
SRD2_k127_2672568_3 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 1.06e-217 695.0
SRD2_k127_2672568_4 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 1.395e-206 649.0
SRD2_k127_2672568_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 614.0
SRD2_k127_2672568_6 Sugar (and other) transporter K03762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 574.0
SRD2_k127_2672568_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 543.0
SRD2_k127_2672568_8 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 438.0
SRD2_k127_2672568_9 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 422.0
SRD2_k127_2682554_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.303e-214 674.0
SRD2_k127_2682554_1 peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 477.0
SRD2_k127_2682554_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 328.0
SRD2_k127_2682554_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 306.0
SRD2_k127_2682554_4 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000001976 169.0
SRD2_k127_2682554_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000001113 90.0
SRD2_k127_272378_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.839e-227 709.0
SRD2_k127_272378_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 1.515e-207 662.0
SRD2_k127_272378_10 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 399.0
SRD2_k127_272378_11 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 390.0
SRD2_k127_272378_12 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 366.0
SRD2_k127_272378_13 FAD-NAD(P)-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 375.0
SRD2_k127_272378_14 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 353.0
SRD2_k127_272378_15 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 353.0
SRD2_k127_272378_16 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004959 258.0
SRD2_k127_272378_17 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000001249 227.0
SRD2_k127_272378_18 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
SRD2_k127_272378_19 - - - - 0.000000000000000000000000000000000000000000000000000000000004676 216.0
SRD2_k127_272378_2 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 6.687e-199 634.0
SRD2_k127_272378_20 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000004714 186.0
SRD2_k127_272378_21 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000000000000000000004863 183.0
SRD2_k127_272378_22 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000003172 171.0
SRD2_k127_272378_23 protein conserved in bacteria - - - 0.00000000000000000000000000000000000001648 147.0
SRD2_k127_272378_24 NifU homolog involved in Fe-S cluster formation - - - 0.00000000000000000000000000002423 124.0
SRD2_k127_272378_26 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000004871 116.0
SRD2_k127_272378_29 - - - - 0.000004765 50.0
SRD2_k127_272378_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.108e-194 619.0
SRD2_k127_272378_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 561.0
SRD2_k127_272378_5 peptidase M48, Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 528.0
SRD2_k127_272378_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 485.0
SRD2_k127_272378_7 PFAM major facilitator superfamily MFS_1 K08169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 483.0
SRD2_k127_272378_8 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 465.0
SRD2_k127_272378_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 403.0
SRD2_k127_2782149_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1087.0
SRD2_k127_2782149_1 GGDEF domain - - - 1.801e-233 734.0
SRD2_k127_2837644_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1089.0
SRD2_k127_2837644_1 receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 567.0
SRD2_k127_2837644_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 282.0
SRD2_k127_2837644_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000171 256.0
SRD2_k127_2837644_12 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000002803 247.0
SRD2_k127_2837644_13 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000006614 233.0
SRD2_k127_2837644_14 Outer membrane protein (OmpH-like) - - - 0.00000000000000000000000000000000000000000000755 170.0
SRD2_k127_2837644_15 - - - - 0.00000000000000000000000000000000000000002632 162.0
SRD2_k127_2837644_16 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000009031 151.0
SRD2_k127_2837644_17 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000000000000000003655 142.0
SRD2_k127_2837644_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000009428 135.0
SRD2_k127_2837644_2 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 535.0
SRD2_k127_2837644_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 459.0
SRD2_k127_2837644_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 462.0
SRD2_k127_2837644_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 434.0
SRD2_k127_2837644_6 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 427.0
SRD2_k127_2837644_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 394.0
SRD2_k127_2837644_8 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 345.0
SRD2_k127_2837644_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 315.0
SRD2_k127_2846105_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 5.172e-274 857.0
SRD2_k127_2846105_1 Belongs to the glycosyl hydrolase 1 family - - - 2.116e-205 654.0
SRD2_k127_2846105_10 Flp pilus assembly protein, pilin Flp K02651 - - 0.0000000000002869 76.0
SRD2_k127_2846105_2 type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 451.0
SRD2_k127_2846105_3 collagen metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 436.0
SRD2_k127_2846105_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 437.0
SRD2_k127_2846105_5 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 413.0
SRD2_k127_2846105_6 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000000000000000000000000000002133 190.0
SRD2_k127_2846105_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000007388 139.0
SRD2_k127_2846105_8 - - - - 0.0000000000000000000000000001475 121.0
SRD2_k127_2846105_9 - - - - 0.00000000000000003831 84.0
SRD2_k127_2849085_0 Sortilin, neurotensin receptor 3, - - - 0.0 1408.0
SRD2_k127_2849085_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.103e-297 915.0
SRD2_k127_2849085_10 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001069 282.0
SRD2_k127_2849085_11 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 264.0
SRD2_k127_2849085_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000004699 232.0
SRD2_k127_2849085_13 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000000000000000000000002045 214.0
SRD2_k127_2849085_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000002797 213.0
SRD2_k127_2849085_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 - - 0.000000000000000000000000000036 118.0
SRD2_k127_2849085_16 methyltransferase - - - 0.000000000000000000000004215 113.0
SRD2_k127_2849085_17 - - - - 0.00000000000000000000002826 99.0
SRD2_k127_2849085_18 GtrA-like protein - - - 0.0000000000002508 75.0
SRD2_k127_2849085_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.316e-276 856.0
SRD2_k127_2849085_3 Flp pilus assembly protein, ATPase CpaF K02283 - - 2.644e-267 833.0
SRD2_k127_2849085_4 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 3.22e-247 779.0
SRD2_k127_2849085_5 Sortilin, neurotensin receptor 3, - - - 5.751e-243 792.0
SRD2_k127_2849085_6 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 437.0
SRD2_k127_2849085_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 404.0
SRD2_k127_2849085_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 297.0
SRD2_k127_2849085_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005567 282.0
SRD2_k127_2876412_0 COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit K01469 - 3.5.2.9 0.0 1656.0
SRD2_k127_2876412_1 Efflux pump membrane transporter K18138 - - 0.0 1450.0
SRD2_k127_2876412_10 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 377.0
SRD2_k127_2876412_11 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002065 280.0
SRD2_k127_2876412_12 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001617 278.0
SRD2_k127_2876412_13 Protein of unknown function (DUF1465) K13592 - - 0.00000000000000000000000000000000000000000000000000000000000347 212.0
SRD2_k127_2876412_14 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000001047 211.0
SRD2_k127_2876412_15 Alpha-amylase domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000008989 181.0
SRD2_k127_2876412_16 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000009236 140.0
SRD2_k127_2876412_18 Small protein - - - 0.0000000000008812 69.0
SRD2_k127_2876412_2 Galactose mutarotase-like - - - 0.0 1053.0
SRD2_k127_2876412_3 Tryptophan halogenase - - - 1.69e-217 685.0
SRD2_k127_2876412_4 RND efflux system, outer membrane lipoprotein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 507.0
SRD2_k127_2876412_5 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 488.0
SRD2_k127_2876412_6 epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 478.0
SRD2_k127_2876412_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 473.0
SRD2_k127_2876412_8 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 438.0
SRD2_k127_2876412_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 376.0
SRD2_k127_2890548_0 peptidase S9 K01278 - 3.4.14.5 0.0 1136.0
SRD2_k127_2890548_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.311e-241 753.0
SRD2_k127_2890548_10 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 301.0
SRD2_k127_2890548_11 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009371 271.0
SRD2_k127_2890548_12 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001572 263.0
SRD2_k127_2890548_13 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001005 256.0
SRD2_k127_2890548_14 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000004142 226.0
SRD2_k127_2890548_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000006234 211.0
SRD2_k127_2890548_16 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000002864 199.0
SRD2_k127_2890548_17 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000006439 200.0
SRD2_k127_2890548_18 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000000000000000004859 194.0
SRD2_k127_2890548_19 - - - - 0.000000000000000000000000000001327 126.0
SRD2_k127_2890548_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 516.0
SRD2_k127_2890548_20 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000015 126.0
SRD2_k127_2890548_22 COG0457 FOG TPR repeat - - - 0.0000000000000000007329 93.0
SRD2_k127_2890548_23 Peptidase family M28 - - - 0.0000000004698 64.0
SRD2_k127_2890548_26 ATP-grasp domain - - - 0.0000007138 53.0
SRD2_k127_2890548_27 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000006179 55.0
SRD2_k127_2890548_3 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 498.0
SRD2_k127_2890548_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 431.0
SRD2_k127_2890548_5 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 417.0
SRD2_k127_2890548_6 Thioredoxin reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 414.0
SRD2_k127_2890548_7 2-methylthioadenine K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 406.0
SRD2_k127_2890548_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 394.0
SRD2_k127_2890548_9 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 356.0
SRD2_k127_2977151_0 aminopeptidase N K01256 - 3.4.11.2 0.0 1127.0
SRD2_k127_2977151_1 Beta-L-arabinofuranosidase, GH127 K09955 - - 1.018e-275 860.0
SRD2_k127_2977151_10 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 385.0
SRD2_k127_2977151_11 Transferrin receptor-like dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 362.0
SRD2_k127_2977151_12 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 366.0
SRD2_k127_2977151_13 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 344.0
SRD2_k127_2977151_14 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003155 270.0
SRD2_k127_2977151_15 Sulfotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002372 260.0
SRD2_k127_2977151_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000339 256.0
SRD2_k127_2977151_17 transport system auxiliary component K18480 - - 0.00000000000000000000000000000000000000000000000000000244 200.0
SRD2_k127_2977151_18 - - - - 0.00000000000000000000000000000000000000000000000001356 183.0
SRD2_k127_2977151_19 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000002101 178.0
SRD2_k127_2977151_2 Peptidase S46 - - - 6.788e-268 841.0
SRD2_k127_2977151_20 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000001764 163.0
SRD2_k127_2977151_21 - - - - 0.00000000000000000000000000000004376 127.0
SRD2_k127_2977151_22 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.000000000000000000000000000002082 121.0
SRD2_k127_2977151_23 - - - - 0.00000000000000000000000000002747 123.0
SRD2_k127_2977151_24 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000005572 124.0
SRD2_k127_2977151_25 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000001918 120.0
SRD2_k127_2977151_26 Polysaccharide deacetylase - - - 0.00000000000000000000003747 110.0
SRD2_k127_2977151_27 Protein of unknown function (DUF3617) - - - 0.00000000000000000000008987 105.0
SRD2_k127_2977151_28 methyltransferase activity - - - 0.00000000000000000000638 101.0
SRD2_k127_2977151_3 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 5.521e-252 811.0
SRD2_k127_2977151_31 COG2826 Transposase and inactivated derivatives, IS30 family K07482 - - 0.0000000000004469 69.0
SRD2_k127_2977151_32 nuclease - - - 0.000000000001111 74.0
SRD2_k127_2977151_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 6.636e-212 661.0
SRD2_k127_2977151_5 glutamate--cysteine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 578.0
SRD2_k127_2977151_6 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 519.0
SRD2_k127_2977151_7 photosynthesis K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 443.0
SRD2_k127_2977151_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 432.0
SRD2_k127_2977151_9 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 421.0
SRD2_k127_299276_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.413e-197 623.0
SRD2_k127_299276_1 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 416.0
SRD2_k127_299276_10 Acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000025 153.0
SRD2_k127_299276_11 Cytochrome C' - - - 0.0000000000000000000000000446 114.0
SRD2_k127_299276_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 354.0
SRD2_k127_299276_3 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 341.0
SRD2_k127_299276_4 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001879 282.0
SRD2_k127_299276_5 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003928 248.0
SRD2_k127_299276_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000007052 231.0
SRD2_k127_299276_7 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000973 223.0
SRD2_k127_299276_8 peptidase M22 - - - 0.00000000000000000000000000000000000000000000000000000001815 205.0
SRD2_k127_299276_9 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000001753 196.0
SRD2_k127_3022912_0 DNA ligase K01971 - 6.5.1.1 0.0 1200.0
SRD2_k127_3022912_1 COG2366 Protein related to penicillin acylase - - - 2.585e-304 948.0
SRD2_k127_3022912_10 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 370.0
SRD2_k127_3022912_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 289.0
SRD2_k127_3022912_12 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000009626 235.0
SRD2_k127_3022912_13 - - - - 0.00000000000006562 78.0
SRD2_k127_3022912_14 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000001271 64.0
SRD2_k127_3022912_2 glutamate--cysteine ligase K01919 - 6.3.2.2 3.69e-243 756.0
SRD2_k127_3022912_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 561.0
SRD2_k127_3022912_4 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 506.0
SRD2_k127_3022912_5 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 435.0
SRD2_k127_3022912_6 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 400.0
SRD2_k127_3022912_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 400.0
SRD2_k127_3022912_8 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 398.0
SRD2_k127_3022912_9 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 388.0
SRD2_k127_3073655_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.875e-215 675.0
SRD2_k127_3073655_1 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 595.0
SRD2_k127_3073655_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 547.0
SRD2_k127_3073655_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000002528 94.0
SRD2_k127_3084116_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 7.392e-320 993.0
SRD2_k127_3084116_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 520.0
SRD2_k127_3084116_2 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 429.0
SRD2_k127_3084116_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 340.0
SRD2_k127_3084116_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 304.0
SRD2_k127_3084116_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000721 160.0
SRD2_k127_3084116_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000004214 154.0
SRD2_k127_3107928_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 3.38e-316 979.0
SRD2_k127_3107928_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 4.445e-246 769.0
SRD2_k127_3107928_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000004291 202.0
SRD2_k127_3131437_0 of ABC transporters with duplicated ATPase K15738 - - 1.163e-296 919.0
SRD2_k127_3131437_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 6.638e-227 722.0
SRD2_k127_3131437_2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 3.771e-218 685.0
SRD2_k127_3131437_3 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 587.0
SRD2_k127_3131437_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 492.0
SRD2_k127_3131437_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 428.0
SRD2_k127_3131437_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 394.0
SRD2_k127_3131437_7 Domain of unknown function (DUF4893) - - - 0.0000000000000000000000000000000000000000000000001008 193.0
SRD2_k127_3131437_8 metalloprotease K07054 - - 0.00000000000000000000000000000000008088 138.0
SRD2_k127_3131437_9 - - - - 0.0000000000000000000000006071 108.0
SRD2_k127_3185289_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1264.0
SRD2_k127_3185289_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1084.0
SRD2_k127_3185289_10 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 477.0
SRD2_k127_3185289_11 D-amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 460.0
SRD2_k127_3185289_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 423.0
SRD2_k127_3185289_13 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 401.0
SRD2_k127_3185289_14 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 387.0
SRD2_k127_3185289_15 ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 375.0
SRD2_k127_3185289_16 Dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 372.0
SRD2_k127_3185289_17 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 364.0
SRD2_k127_3185289_18 COG0491 Zn-dependent hydrolases, including glyoxylases K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 362.0
SRD2_k127_3185289_19 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 360.0
SRD2_k127_3185289_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1037.0
SRD2_k127_3185289_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 354.0
SRD2_k127_3185289_21 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 311.0
SRD2_k127_3185289_22 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 309.0
SRD2_k127_3185289_23 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 298.0
SRD2_k127_3185289_24 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001682 285.0
SRD2_k127_3185289_25 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003034 260.0
SRD2_k127_3185289_26 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004464 251.0
SRD2_k127_3185289_27 Diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000105 231.0
SRD2_k127_3185289_28 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000001917 183.0
SRD2_k127_3185289_29 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000000000000000007986 181.0
SRD2_k127_3185289_3 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.673e-241 759.0
SRD2_k127_3185289_30 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000001505 187.0
SRD2_k127_3185289_31 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000383 174.0
SRD2_k127_3185289_32 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000000000000001209 160.0
SRD2_k127_3185289_33 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000001218 149.0
SRD2_k127_3185289_34 succinate dehydrogenase activity K00242 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000001896 149.0
SRD2_k127_3185289_35 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000002938 143.0
SRD2_k127_3185289_36 - - - - 0.00000000000000000000000000000000005507 139.0
SRD2_k127_3185289_37 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000001785 133.0
SRD2_k127_3185289_38 - - - - 0.00000000000000000000000001929 119.0
SRD2_k127_3185289_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 5.461e-229 720.0
SRD2_k127_3185289_40 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000003163 63.0
SRD2_k127_3185289_42 Mobile mystery protein B - - - 0.0000551 49.0
SRD2_k127_3185289_5 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 6.013e-221 698.0
SRD2_k127_3185289_6 peptidase S10 serine carboxypeptidase - - - 2.562e-219 694.0
SRD2_k127_3185289_7 histidine kinase A domain protein - - - 5.991e-208 664.0
SRD2_k127_3185289_8 May be involved in recombinational repair of damaged DNA K03631 - - 2.026e-195 623.0
SRD2_k127_3185289_9 rod shape-determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 549.0
SRD2_k127_3361274_0 Bacterial sugar transferase K21303 - 2.7.8.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007021 496.0
SRD2_k127_3361274_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 330.0
SRD2_k127_3361274_2 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000009019 205.0
SRD2_k127_3392309_0 Ring hydroxylating alpha subunit (catalytic domain) - - - 2.117e-203 640.0
SRD2_k127_3392309_1 protein conserved in bacteria K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 434.0
SRD2_k127_3392309_10 amino acid K03294 - - 0.00000000000000000000000000000000000000003069 167.0
SRD2_k127_3392309_11 - - - - 0.0000000000000000000000000000000000000006101 155.0
SRD2_k127_3392309_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000001912 141.0
SRD2_k127_3392309_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 409.0
SRD2_k127_3392309_3 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 308.0
SRD2_k127_3392309_4 PFAM inositol monophosphatase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 291.0
SRD2_k127_3392309_5 XRE family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001893 254.0
SRD2_k127_3392309_6 amino acid K03294,K03759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000901 265.0
SRD2_k127_3392309_7 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000002335 251.0
SRD2_k127_3392309_8 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000172 219.0
SRD2_k127_3392309_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000004839 190.0
SRD2_k127_3435428_0 Belongs to the TPP enzyme family K00156 - 1.2.5.1 1.001e-249 779.0
SRD2_k127_3435428_1 histidine kinase A domain protein - - - 1.435e-209 684.0
SRD2_k127_3550925_0 Histidine kinase - - - 1.355e-283 896.0
SRD2_k127_3550925_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 428.0
SRD2_k127_3550925_10 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000002108 117.0
SRD2_k127_3550925_11 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000003666 122.0
SRD2_k127_3550925_2 Repeat of Unknown Function (DUF347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 410.0
SRD2_k127_3550925_3 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 384.0
SRD2_k127_3550925_4 Osmosensitive K channel K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 321.0
SRD2_k127_3550925_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 285.0
SRD2_k127_3550925_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004786 261.0
SRD2_k127_3550925_7 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000002326 214.0
SRD2_k127_3550925_8 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.0000000000000000000000000000000000000000000005656 173.0
SRD2_k127_3550925_9 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000003038 177.0
SRD2_k127_3561678_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1084.0
SRD2_k127_3561678_1 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 0.0 1028.0
SRD2_k127_3561678_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 396.0
SRD2_k127_3561678_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
SRD2_k127_3561678_12 NADH dehydrogenase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 368.0
SRD2_k127_3561678_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 317.0
SRD2_k127_3561678_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 325.0
SRD2_k127_3561678_15 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
SRD2_k127_3561678_16 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000001024 213.0
SRD2_k127_3561678_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000001091 153.0
SRD2_k127_3561678_18 Protein of unknown function (DUF1467) - - - 0.0000000000000000000000000004197 117.0
SRD2_k127_3561678_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 8.069e-254 789.0
SRD2_k127_3561678_3 metallo-beta-lactamase K12574 - - 2.409e-242 760.0
SRD2_k127_3561678_4 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 5.605e-237 744.0
SRD2_k127_3561678_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 7.543e-213 663.0
SRD2_k127_3561678_6 domain protein - - - 5.421e-207 668.0
SRD2_k127_3561678_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 626.0
SRD2_k127_3561678_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 587.0
SRD2_k127_3561678_9 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 574.0
SRD2_k127_3563420_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1135.0
SRD2_k127_3563420_1 Acetoacetyl-CoA reductase K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 409.0
SRD2_k127_3563420_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 407.0
SRD2_k127_3563420_3 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 315.0
SRD2_k127_3563420_4 Ribbon-helix-helix domain - - - 0.000002063 53.0
SRD2_k127_3607089_0 TonB dependent receptor - - - 0.0 1239.0
SRD2_k127_3607089_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.812e-262 813.0
SRD2_k127_3607089_10 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 423.0
SRD2_k127_3607089_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 370.0
SRD2_k127_3607089_12 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 332.0
SRD2_k127_3607089_13 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 316.0
SRD2_k127_3607089_14 3-deoxy-manno-octulosonate cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003105 275.0
SRD2_k127_3607089_15 sugar phosphatases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001678 258.0
SRD2_k127_3607089_16 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005656 250.0
SRD2_k127_3607089_17 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000008333 153.0
SRD2_k127_3607089_18 Alkaline phosphatase with broad substrate specificity K01077 - 3.1.3.1 0.00000000000000000000000000000000000002717 156.0
SRD2_k127_3607089_19 Protein of unknown function (DUF3089) - - - 0.00000000000728 66.0
SRD2_k127_3607089_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 8.847e-237 741.0
SRD2_k127_3607089_20 - - - - 0.000005036 56.0
SRD2_k127_3607089_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 8.105e-198 620.0
SRD2_k127_3607089_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.296e-196 627.0
SRD2_k127_3607089_5 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 1.751e-194 615.0
SRD2_k127_3607089_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 554.0
SRD2_k127_3607089_7 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 502.0
SRD2_k127_3607089_8 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 484.0
SRD2_k127_3607089_9 Major facilitator superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 475.0
SRD2_k127_3748370_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 7.312e-304 939.0
SRD2_k127_3748370_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 381.0
SRD2_k127_3748370_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
SRD2_k127_3748370_3 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000002045 201.0
SRD2_k127_382664_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1062.0
SRD2_k127_382664_1 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 414.0
SRD2_k127_382664_2 Nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 290.0
SRD2_k127_382664_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000002639 236.0
SRD2_k127_382664_4 Cold-shock protein K03704 - - 0.0000000000000000000000000004044 115.0
SRD2_k127_382664_5 - - - - 0.0000000000000000005213 87.0
SRD2_k127_382664_6 - - - - 0.0000008603 53.0
SRD2_k127_3867335_0 amine dehydrogenase activity - - - 0.0 1255.0
SRD2_k127_3867335_1 protein conserved in bacteria - - - 1.605e-208 668.0
SRD2_k127_3867335_2 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 382.0
SRD2_k127_3867335_3 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 329.0
SRD2_k127_3867335_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000000005003 161.0
SRD2_k127_3876158_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 498.0
SRD2_k127_3876158_1 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 409.0
SRD2_k127_3876158_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 366.0
SRD2_k127_3876158_3 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000154 176.0
SRD2_k127_3876158_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000004095 146.0
SRD2_k127_3876158_5 Periplasmic or secreted lipoprotein - - - 0.0000000000000859 74.0
SRD2_k127_3876158_6 PhoQ Sensor - - - 0.00000000006631 72.0
SRD2_k127_3876158_7 Transcriptional regulator - - - 0.000000003143 67.0
SRD2_k127_4001179_0 Histidine kinase - - - 1.138e-221 706.0
SRD2_k127_4001179_1 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 543.0
SRD2_k127_4001179_2 chemotaxis protein K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002369 278.0
SRD2_k127_4001179_3 Nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001194 248.0
SRD2_k127_4001179_4 response regulator - - - 0.00000000000000000000000000000000000000000000000005628 180.0
SRD2_k127_4001179_5 - - - - 0.00000000255 61.0
SRD2_k127_4049031_0 Aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 4.444e-202 639.0
SRD2_k127_4049031_1 CHASE2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 370.0
SRD2_k127_4049031_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000003342 133.0
SRD2_k127_4049031_3 Aminotransferase - - - 0.0000000000000000000008686 96.0
SRD2_k127_4078647_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 565.0
SRD2_k127_4078647_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 561.0
SRD2_k127_4078647_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 543.0
SRD2_k127_4078647_3 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 531.0
SRD2_k127_4078647_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002954 279.0
SRD2_k127_4078647_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000006542 228.0
SRD2_k127_4078647_6 membrane - - - 0.000000000000000000000000000000003426 134.0
SRD2_k127_4106940_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.932e-249 771.0
SRD2_k127_4106940_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 486.0
SRD2_k127_4106940_10 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000006049 219.0
SRD2_k127_4106940_11 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000000000000000000001616 216.0
SRD2_k127_4106940_12 COG3773 Cell wall hydrolyses involved in spore germination - - - 0.0000000000000000000000000000000000000000000000000003432 192.0
SRD2_k127_4106940_13 Protein of unknown function (DUF1491) - - - 0.000000000000000000002592 100.0
SRD2_k127_4106940_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 456.0
SRD2_k127_4106940_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 441.0
SRD2_k127_4106940_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 331.0
SRD2_k127_4106940_5 membrane protein, TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008252 257.0
SRD2_k127_4106940_6 membrane K08973 - - 0.000000000000000000000000000000000000000000000000000000000000000001734 231.0
SRD2_k127_4106940_7 DNA repair protein MmcB-like - - - 0.000000000000000000000000000000000000000000000000000000000000000002063 229.0
SRD2_k127_4106940_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000001526 221.0
SRD2_k127_4106940_9 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.00000000000000000000000000000000000000000000000000000000000005165 222.0
SRD2_k127_4108582_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 585.0
SRD2_k127_4108582_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 436.0
SRD2_k127_4108582_2 peptidase S9 K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 314.0
SRD2_k127_4108582_3 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008807 251.0
SRD2_k127_4137991_0 Major Facilitator - - - 4.823e-219 694.0
SRD2_k127_4137991_1 receptor - - - 7.417e-216 689.0
SRD2_k127_4137991_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.055e-204 641.0
SRD2_k127_4137991_3 6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 353.0
SRD2_k127_4137991_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000002875 173.0
SRD2_k127_4137991_5 - - - - 0.00000000000000000000000008117 114.0
SRD2_k127_4137991_6 Protein of unknown function (DUF3833) - - - 0.000000000000000000000001154 112.0
SRD2_k127_4137991_7 Stress-induced bacterial acidophilic repeat motif - - - 0.000001395 51.0
SRD2_k127_4167921_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1010.0
SRD2_k127_4167921_1 Sigma factor PP2C-like phosphatases - - - 1.613e-226 721.0
SRD2_k127_4167921_10 F5/8 type C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 423.0
SRD2_k127_4167921_11 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 409.0
SRD2_k127_4167921_12 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 377.0
SRD2_k127_4167921_13 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 377.0
SRD2_k127_4167921_14 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 364.0
SRD2_k127_4167921_15 CHASE2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 344.0
SRD2_k127_4167921_17 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 299.0
SRD2_k127_4167921_18 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 312.0
SRD2_k127_4167921_19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 294.0
SRD2_k127_4167921_2 Belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 7.015e-199 640.0
SRD2_k127_4167921_20 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002705 274.0
SRD2_k127_4167921_21 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002259 276.0
SRD2_k127_4167921_22 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
SRD2_k127_4167921_23 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002203 267.0
SRD2_k127_4167921_24 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007206 254.0
SRD2_k127_4167921_25 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 251.0
SRD2_k127_4167921_26 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000000000000000000000001192 241.0
SRD2_k127_4167921_27 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
SRD2_k127_4167921_28 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000002624 229.0
SRD2_k127_4167921_29 FecR protein - - - 0.00000000000000000000000000000000000000000000001224 175.0
SRD2_k127_4167921_3 Amidohydrolase family - - - 2.269e-195 620.0
SRD2_k127_4167921_30 dNA-binding protein - - - 0.00000000000000000000000000000000000000000000006038 175.0
SRD2_k127_4167921_31 OmpA family - - - 0.00000000000000000000000000000000000000000000006973 177.0
SRD2_k127_4167921_32 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000005125 154.0
SRD2_k127_4167921_33 Dopa 4,5-dioxygenase family K10253 - - 0.00000000000000000000000000000000000003334 149.0
SRD2_k127_4167921_34 MerC mercury resistance protein - - - 0.0000000000000000000000000000000002659 136.0
SRD2_k127_4167921_35 Membrane fusogenic activity K09806 - - 0.000000000000000000000000000001047 124.0
SRD2_k127_4167921_36 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000136 128.0
SRD2_k127_4167921_37 - - - - 0.000000000000000000000000006638 114.0
SRD2_k127_4167921_38 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000002594 108.0
SRD2_k127_4167921_39 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000318 109.0
SRD2_k127_4167921_4 belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 601.0
SRD2_k127_4167921_40 - - - - 0.000000000000000000000005872 106.0
SRD2_k127_4167921_41 Histidine kinase-like ATPase domain - - - 0.0000000000000000000002062 103.0
SRD2_k127_4167921_42 integral membrane protein - - - 0.000000000000000000001573 103.0
SRD2_k127_4167921_44 - - - - 0.000000000000000994 83.0
SRD2_k127_4167921_45 - - - - 0.0000000000001646 78.0
SRD2_k127_4167921_46 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000001536 53.0
SRD2_k127_4167921_48 - - - - 0.000946 44.0
SRD2_k127_4167921_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 574.0
SRD2_k127_4167921_6 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 483.0
SRD2_k127_4167921_7 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 470.0
SRD2_k127_4167921_8 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 433.0
SRD2_k127_4167921_9 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 442.0
SRD2_k127_4252993_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1557.0
SRD2_k127_4252993_1 COG1505 Serine proteases of the peptidase family S9A K01322 - 3.4.21.26 0.0 1072.0
SRD2_k127_4252993_10 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 515.0
SRD2_k127_4252993_11 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 501.0
SRD2_k127_4252993_12 imidazolonepropionase activity K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 407.0
SRD2_k127_4252993_13 Galactose 1-dehydrogenase K00035 - 1.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 407.0
SRD2_k127_4252993_14 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 371.0
SRD2_k127_4252993_15 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 301.0
SRD2_k127_4252993_16 Aminomethyltransferase K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 284.0
SRD2_k127_4252993_17 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006436 284.0
SRD2_k127_4252993_18 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003979 280.0
SRD2_k127_4252993_19 Aldolase K01631 - 4.1.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000002234 259.0
SRD2_k127_4252993_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 6.036e-318 977.0
SRD2_k127_4252993_20 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000006949 237.0
SRD2_k127_4252993_21 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
SRD2_k127_4252993_22 Iron-sulfur cluster assembly protein K02612 - - 0.0000000000000000000000000000000000000000000000000000000000005151 215.0
SRD2_k127_4252993_23 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000003855 201.0
SRD2_k127_4252993_24 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000001605 185.0
SRD2_k127_4252993_25 SOS response K14160 - - 0.00000000000000000000000000000000000000000000001252 179.0
SRD2_k127_4252993_26 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000001254 117.0
SRD2_k127_4252993_27 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000009198 112.0
SRD2_k127_4252993_28 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000009361 87.0
SRD2_k127_4252993_29 Flp pilus assembly protein, pilin Flp K02651 - - 0.0000005419 54.0
SRD2_k127_4252993_3 protein conserved in bacteria - - - 9.379e-265 830.0
SRD2_k127_4252993_4 Glycosyl hydrolase family 1 - - - 4.7e-231 719.0
SRD2_k127_4252993_5 Histidine K01745 - 4.3.1.3 2.621e-222 703.0
SRD2_k127_4252993_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.486e-201 636.0
SRD2_k127_4252993_7 mandelate racemase muconate lactonizing K01684,K01781,K08323 - 4.2.1.6,4.2.1.8,5.1.2.2 2.642e-197 620.0
SRD2_k127_4252993_8 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 617.0
SRD2_k127_4252993_9 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 529.0
SRD2_k127_4254579_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 1.916e-288 900.0
SRD2_k127_4254579_1 usher protein - - - 1.384e-272 866.0
SRD2_k127_4254579_10 Domain of unknown function (DUF4402) - - - 0.000000000000000531 85.0
SRD2_k127_4254579_2 cell division K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 376.0
SRD2_k127_4254579_3 COG3121 P pilus assembly protein, chaperone PapD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 298.0
SRD2_k127_4254579_4 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000000000000000000000000002808 231.0
SRD2_k127_4254579_5 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000000000000000004028 221.0
SRD2_k127_4254579_6 Cell division protein K09811 - - 0.000000000000000000000000000000000000000000000003412 183.0
SRD2_k127_4254579_7 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000326 185.0
SRD2_k127_4254579_8 Domain of unknown function (DUF4402) - - - 0.0000000000000000000000000000000000000006263 154.0
SRD2_k127_4254579_9 Ankyrin repeat - - - 0.0000000000000000000000000000000000002485 159.0
SRD2_k127_4262111_0 4Fe-4S dicluster domain - - - 0.0 1209.0
SRD2_k127_4262111_1 Dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000005732 213.0
SRD2_k127_4262111_2 PEP-CTERM motif - - - 0.000000000000000000000000000000000000001286 156.0
SRD2_k127_4311786_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 604.0
SRD2_k127_4311786_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 534.0
SRD2_k127_4311786_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000003096 204.0
SRD2_k127_4311786_11 dioxygenase of extradiol dioxygenase family K06991 - - 0.00000000000000000000000000000000000000000000000000002934 207.0
SRD2_k127_4311786_12 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000003611 149.0
SRD2_k127_4311786_2 Chalcone and stilbene synthases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 471.0
SRD2_k127_4311786_3 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 463.0
SRD2_k127_4311786_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 384.0
SRD2_k127_4311786_5 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 391.0
SRD2_k127_4311786_6 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 384.0
SRD2_k127_4311786_7 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 341.0
SRD2_k127_4311786_8 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000001304 226.0
SRD2_k127_4311786_9 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000547 208.0
SRD2_k127_4544331_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.788e-278 877.0
SRD2_k127_4544331_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 569.0
SRD2_k127_4544331_10 Transglycosylase associated protein - - - 0.00000000000000000000000000005979 117.0
SRD2_k127_4544331_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 494.0
SRD2_k127_4544331_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 407.0
SRD2_k127_4544331_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 309.0
SRD2_k127_4544331_5 PhzC PhzF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 302.0
SRD2_k127_4544331_6 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000000000000000000002348 238.0
SRD2_k127_4544331_7 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000000000000000000000000662 181.0
SRD2_k127_4544331_8 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000005169 189.0
SRD2_k127_4544331_9 Transglycosylase associated protein - - - 0.000000000000000000000000000000114 128.0
SRD2_k127_4545372_0 Amidohydrolase family K06015 - 3.5.1.81 1.245e-237 748.0
SRD2_k127_4545372_1 UDP-N-acetylmuramate-alanine ligase K01924 - 6.3.2.8 1.749e-197 625.0
SRD2_k127_4545372_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 324.0
SRD2_k127_4545372_3 proteins, homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 317.0
SRD2_k127_4545372_4 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000002195 225.0
SRD2_k127_4545372_5 - - - - 0.000000000000000000000000000000000000000000000000000000002162 204.0
SRD2_k127_4545372_6 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000007954 130.0
SRD2_k127_4562345_0 WD40-like Beta Propeller Repeat - - - 0.0 1170.0
SRD2_k127_4562345_1 Phytochrome region - - - 0.0 1111.0
SRD2_k127_4562345_10 Flp pilus assembly protein, pilin Flp K02651 - - 0.00000000000001531 74.0
SRD2_k127_4562345_11 Histidine kinase - - - 0.00000000000003399 82.0
SRD2_k127_4562345_2 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 1.788e-298 923.0
SRD2_k127_4562345_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 557.0
SRD2_k127_4562345_4 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001504 250.0
SRD2_k127_4562345_5 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000009025 194.0
SRD2_k127_4562345_6 HWE histidine kinase - - - 0.0000000000000000000000000000000000000001616 163.0
SRD2_k127_4562345_7 heme oxygenase K07215 - 1.14.99.58 0.000000000000000000000002974 113.0
SRD2_k127_4562345_8 - - - - 0.0000000000000002768 83.0
SRD2_k127_4562345_9 Flp pilus assembly protein, pilin Flp K02651 - - 0.000000000000002692 77.0
SRD2_k127_4582447_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 1.455e-229 722.0
SRD2_k127_4582447_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 603.0
SRD2_k127_4582447_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 520.0
SRD2_k127_4582447_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000104 211.0
SRD2_k127_4582447_4 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000006313 208.0
SRD2_k127_4582447_5 Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000000000000000007594 200.0
SRD2_k127_4582447_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000003423 92.0
SRD2_k127_4582447_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000768 53.0
SRD2_k127_4846224_0 Major facilitator superfamily K03446 - - 1.211e-220 694.0
SRD2_k127_4846224_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 488.0
SRD2_k127_4846224_10 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001523 271.0
SRD2_k127_4846224_11 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002626 243.0
SRD2_k127_4846224_12 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000001563 196.0
SRD2_k127_4846224_13 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000001813 166.0
SRD2_k127_4846224_14 - - - - 0.0000000000000000000000000001699 116.0
SRD2_k127_4846224_15 Protein conserved in bacteria K09780 - - 0.00001178 51.0
SRD2_k127_4846224_16 pathogenesis - - - 0.000307 51.0
SRD2_k127_4846224_17 EF hand - - - 0.0003509 52.0
SRD2_k127_4846224_18 DUF167 K09131 - - 0.0006609 49.0
SRD2_k127_4846224_2 coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 452.0
SRD2_k127_4846224_3 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 463.0
SRD2_k127_4846224_4 Secretion protein, HlyD K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 383.0
SRD2_k127_4846224_5 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 364.0
SRD2_k127_4846224_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 343.0
SRD2_k127_4846224_7 Nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 325.0
SRD2_k127_4846224_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 299.0
SRD2_k127_4846224_9 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 286.0
SRD2_k127_4921242_0 N-carbamoylputrescine amidase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 504.0
SRD2_k127_4921242_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 481.0
SRD2_k127_4921242_2 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 312.0
SRD2_k127_4921242_3 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000002937 210.0
SRD2_k127_4921242_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000003472 183.0
SRD2_k127_4968748_0 Sugar (and other) transporter - - - 7.919e-212 667.0
SRD2_k127_4968748_1 Major Facilitator Superfamily K02429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 526.0
SRD2_k127_4968748_2 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 507.0
SRD2_k127_4968748_3 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 430.0
SRD2_k127_4968748_4 Gluconolactonase K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 353.0
SRD2_k127_4968748_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003089 248.0
SRD2_k127_4968748_6 glutamate dehydrogenase K15371 - 1.4.1.2 0.0000000000000000000000000000000135 132.0
SRD2_k127_4968748_7 - - - - 0.000000000002021 73.0
SRD2_k127_5011817_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1635.0
SRD2_k127_5011817_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1256.0
SRD2_k127_5011817_10 Belongs to the BI1 family K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 311.0
SRD2_k127_5011817_11 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 292.0
SRD2_k127_5011817_12 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 291.0
SRD2_k127_5011817_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001206 254.0
SRD2_k127_5011817_14 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000000000000000000000000008476 205.0
SRD2_k127_5011817_15 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000003632 200.0
SRD2_k127_5011817_16 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000001391 199.0
SRD2_k127_5011817_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000008463 188.0
SRD2_k127_5011817_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000004061 172.0
SRD2_k127_5011817_19 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000004174 158.0
SRD2_k127_5011817_2 Prolyl oligopeptidase family - - - 3.72e-279 874.0
SRD2_k127_5011817_20 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000504 136.0
SRD2_k127_5011817_21 - - - - 0.00000000000000000000000000007107 124.0
SRD2_k127_5011817_22 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000004165 109.0
SRD2_k127_5011817_23 Phospholipase/Carboxylesterase - - - 0.000000000000008709 81.0
SRD2_k127_5011817_24 Protein of unknown function (DUF1192) - - - 0.000000001735 64.0
SRD2_k127_5011817_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 6.464e-252 793.0
SRD2_k127_5011817_4 Peptidase, M28 - - - 1.434e-220 700.0
SRD2_k127_5011817_5 NADPH quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 457.0
SRD2_k127_5011817_6 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 367.0
SRD2_k127_5011817_7 protein conserved in bacteria K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 366.0
SRD2_k127_5011817_8 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 343.0
SRD2_k127_5011817_9 Protein phosphatase 2A homologues, catalytic domain. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 323.0
SRD2_k127_5082392_0 helicase K03724 - - 0.0 1230.0
SRD2_k127_5082392_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1222.0
SRD2_k127_5082392_10 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 - - 4.47e-283 882.0
SRD2_k127_5082392_11 synthetase K01897 - 6.2.1.3 4.074e-273 852.0
SRD2_k127_5082392_12 phosphomannomutase K01840 - 5.4.2.8 3.281e-219 706.0
SRD2_k127_5082392_13 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.143e-215 684.0
SRD2_k127_5082392_14 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.557e-213 672.0
SRD2_k127_5082392_15 UDP-galactopyranose mutase K01854 - 5.4.99.9 1.065e-194 616.0
SRD2_k127_5082392_16 GvpD gas vesicle protein K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 603.0
SRD2_k127_5082392_17 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 587.0
SRD2_k127_5082392_18 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 550.0
SRD2_k127_5082392_19 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 555.0
SRD2_k127_5082392_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0 1216.0
SRD2_k127_5082392_20 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 539.0
SRD2_k127_5082392_21 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 501.0
SRD2_k127_5082392_22 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 477.0
SRD2_k127_5082392_23 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 469.0
SRD2_k127_5082392_24 Protein of unknown function (DUF3089) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 470.0
SRD2_k127_5082392_25 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 448.0
SRD2_k127_5082392_26 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 437.0
SRD2_k127_5082392_27 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 406.0
SRD2_k127_5082392_28 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 392.0
SRD2_k127_5082392_29 Alternative oxidase K17893 - 1.10.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 391.0
SRD2_k127_5082392_3 Malic enzyme K00029 - 1.1.1.40 0.0 1187.0
SRD2_k127_5082392_30 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 400.0
SRD2_k127_5082392_31 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 377.0
SRD2_k127_5082392_32 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 370.0
SRD2_k127_5082392_33 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 367.0
SRD2_k127_5082392_34 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 370.0
SRD2_k127_5082392_35 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 364.0
SRD2_k127_5082392_36 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 336.0
SRD2_k127_5082392_37 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 336.0
SRD2_k127_5082392_38 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 316.0
SRD2_k127_5082392_39 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 312.0
SRD2_k127_5082392_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1120.0
SRD2_k127_5082392_40 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 305.0
SRD2_k127_5082392_41 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 310.0
SRD2_k127_5082392_42 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 308.0
SRD2_k127_5082392_43 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 294.0
SRD2_k127_5082392_44 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 290.0
SRD2_k127_5082392_45 CorA-like Mg2+ transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 291.0
SRD2_k127_5082392_46 Chromosome partitioning - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 271.0
SRD2_k127_5082392_47 ABC-type transport system involved in Fe-S cluster assembly, permease component K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005501 258.0
SRD2_k127_5082392_48 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002781 248.0
SRD2_k127_5082392_49 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000001455 241.0
SRD2_k127_5082392_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1103.0
SRD2_k127_5082392_50 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000002121 232.0
SRD2_k127_5082392_51 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000002955 229.0
SRD2_k127_5082392_52 thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000776 188.0
SRD2_k127_5082392_53 redox protein, regulator of disulfide bond formation K04063 - - 0.000000000000000000000000000000000000000000000000001704 186.0
SRD2_k127_5082392_54 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000223 186.0
SRD2_k127_5082392_55 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000672 173.0
SRD2_k127_5082392_56 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000005402 169.0
SRD2_k127_5082392_57 - - - - 0.000000000000000000000000000000000000000000008376 168.0
SRD2_k127_5082392_58 transcriptional - - - 0.000000000000000000000000000000000000000000008428 171.0
SRD2_k127_5082392_59 3' exoribonuclease, RNase T-like - - - 0.0000000000000000000000000000000000000000002273 165.0
SRD2_k127_5082392_6 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0 1060.0
SRD2_k127_5082392_60 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000001003 153.0
SRD2_k127_5082392_61 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000008028 154.0
SRD2_k127_5082392_62 - - - - 0.000000000000000000000000000000000000008375 156.0
SRD2_k127_5082392_63 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.000000000000000000000000000000000008338 143.0
SRD2_k127_5082392_64 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01286,K01992,K07258 - 3.4.16.4 0.000000000000000000000000000000003748 136.0
SRD2_k127_5082392_65 Belongs to the UPF0335 family - - - 0.000000000000000000000000000001313 122.0
SRD2_k127_5082392_66 - - - - 0.00000000000000000000000003674 113.0
SRD2_k127_5082392_67 - - - - 0.000000000000000000000002175 112.0
SRD2_k127_5082392_68 - - - - 0.000000000000000000000002571 108.0
SRD2_k127_5082392_69 COG0457 FOG TPR repeat - - - 0.000000000000000000000005111 110.0
SRD2_k127_5082392_7 MacB-like periplasmic core domain K02004 - - 3.938e-320 1000.0
SRD2_k127_5082392_70 Transcriptional regulator K07729 - - 0.00000000000000000000002171 109.0
SRD2_k127_5082392_72 - - - - 0.0000000000000000000006967 108.0
SRD2_k127_5082392_73 Helix-turn-helix domain K07729 - - 0.0000000000000000000344 92.0
SRD2_k127_5082392_75 Belongs to the ompA family K03640 - - 0.000000000000003413 82.0
SRD2_k127_5082392_76 - - - - 0.0000000005772 64.0
SRD2_k127_5082392_77 - - - - 0.0002746 48.0
SRD2_k127_5082392_8 MacB-like periplasmic core domain K02004 - - 2.164e-309 969.0
SRD2_k127_5082392_9 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 1.701e-294 908.0
SRD2_k127_5104092_0 Domain of unknown function DUF87 K06915 - - 1.872e-298 923.0
SRD2_k127_5104092_1 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 343.0
SRD2_k127_5104092_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 308.0
SRD2_k127_5104092_3 N-terminal domain of galactosyltransferase - - - 0.0000000000000000000000883 108.0
SRD2_k127_514654_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1133.0
SRD2_k127_514654_1 Transferrin receptor-like dimerisation domain - - - 0.0 1035.0
SRD2_k127_514654_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 565.0
SRD2_k127_514654_3 - - - - 0.0000000000000000000000000006956 118.0
SRD2_k127_5189133_0 ATP-dependent helicase K03579 - 3.6.4.13 0.0 1152.0
SRD2_k127_5189133_1 response regulator - - - 3.508e-235 740.0
SRD2_k127_5189133_10 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000008676 167.0
SRD2_k127_5189133_11 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000001421 158.0
SRD2_k127_5189133_12 ETC complex I subunit - - - 0.0000000000000000000000000000000000004396 145.0
SRD2_k127_5189133_13 protein conserved in bacteria - - - 0.0000000000000000000000000000001343 133.0
SRD2_k127_5189133_14 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000004147 128.0
SRD2_k127_5189133_15 - - - - 0.00000000000000000011 92.0
SRD2_k127_5189133_2 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 3.54e-209 674.0
SRD2_k127_5189133_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.225e-198 634.0
SRD2_k127_5189133_4 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 537.0
SRD2_k127_5189133_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 323.0
SRD2_k127_5189133_6 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 316.0
SRD2_k127_5189133_7 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 288.0
SRD2_k127_5189133_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001265 238.0
SRD2_k127_5189133_9 - - - - 0.000000000000000000000000000000000000000000000000000000003243 209.0
SRD2_k127_520198_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 599.0
SRD2_k127_520198_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 592.0
SRD2_k127_520198_2 - - - - 0.0000000001064 64.0
SRD2_k127_5207445_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1200.0
SRD2_k127_5207445_1 ATP-dependent DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.298e-257 803.0
SRD2_k127_5207445_10 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 552.0
SRD2_k127_5207445_11 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 549.0
SRD2_k127_5207445_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 512.0
SRD2_k127_5207445_13 protein conserved in bacteria K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 501.0
SRD2_k127_5207445_14 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 474.0
SRD2_k127_5207445_15 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 441.0
SRD2_k127_5207445_16 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 430.0
SRD2_k127_5207445_17 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 418.0
SRD2_k127_5207445_18 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 376.0
SRD2_k127_5207445_19 endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 358.0
SRD2_k127_5207445_2 protease with the C-terminal PDZ - - - 5.576e-248 782.0
SRD2_k127_5207445_20 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 349.0
SRD2_k127_5207445_21 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 344.0
SRD2_k127_5207445_22 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 349.0
SRD2_k127_5207445_23 Cold shock K03704 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 346.0
SRD2_k127_5207445_24 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 304.0
SRD2_k127_5207445_25 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 298.0
SRD2_k127_5207445_26 DNA mediated transformation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000374 302.0
SRD2_k127_5207445_27 EamA-like transporter family K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000001109 240.0
SRD2_k127_5207445_28 endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000003487 235.0
SRD2_k127_5207445_29 Protein conserved in bacteria K11719 - - 0.000000000000000000000000000000000000000000000000000000000000001495 226.0
SRD2_k127_5207445_3 Outer membrane receptor proteins, mostly Fe transport - - - 3.102e-227 734.0
SRD2_k127_5207445_30 protein conserved in bacteria K09774 - - 0.000000000000000000000000000000000000000000000000000000000000481 220.0
SRD2_k127_5207445_31 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000000000002768 199.0
SRD2_k127_5207445_32 Acyl-CoA hydrolase K10806 - - 0.00000000000000000000000000000000000000000000000000002735 189.0
SRD2_k127_5207445_33 Small Multidrug Resistance protein K11741 - - 0.0000000000000000000000000000000000000000000001146 170.0
SRD2_k127_5207445_34 CBS domain - - - 0.000000000000000000000000000000000000000000001261 171.0
SRD2_k127_5207445_35 response regulator K11443 - - 0.000000000000000000000000000000000000000000002007 169.0
SRD2_k127_5207445_36 Domain of unknown function (DUF4167) - - - 0.00000000000000000000000000000000000000007328 158.0
SRD2_k127_5207445_37 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000001263 157.0
SRD2_k127_5207445_38 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000006282 102.0
SRD2_k127_5207445_39 Protein of unknown function (DUF3572) - - - 0.0000000000000000002331 90.0
SRD2_k127_5207445_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.089e-211 660.0
SRD2_k127_5207445_40 - - - - 0.0000000000000000002669 90.0
SRD2_k127_5207445_42 - - - - 0.000000000002954 72.0
SRD2_k127_5207445_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 6.461e-203 635.0
SRD2_k127_5207445_6 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 584.0
SRD2_k127_5207445_7 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 575.0
SRD2_k127_5207445_8 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 556.0
SRD2_k127_5207445_9 peptidase S10 serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 565.0
SRD2_k127_5285265_0 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 580.0
SRD2_k127_5285265_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 557.0
SRD2_k127_5285265_10 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000000000000001391 246.0
SRD2_k127_5285265_11 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007292 236.0
SRD2_k127_5285265_12 Universal stress protein - - - 0.000000000000000000000000000000000000000000000005567 194.0
SRD2_k127_5285265_13 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000004304 176.0
SRD2_k127_5285265_14 chain release factor K15034 - - 0.000000000000000000000000000000000000000001439 162.0
SRD2_k127_5285265_15 acyl-CoA thioester hydrolase K10806 - - 0.0000000000000000000000000000000000000000157 158.0
SRD2_k127_5285265_16 Putative zinc-finger - - - 0.000000000000000000000000000000003253 141.0
SRD2_k127_5285265_17 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000002241 86.0
SRD2_k127_5285265_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 503.0
SRD2_k127_5285265_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 451.0
SRD2_k127_5285265_4 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 443.0
SRD2_k127_5285265_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 410.0
SRD2_k127_5285265_6 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 374.0
SRD2_k127_5285265_7 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 339.0
SRD2_k127_5285265_8 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 326.0
SRD2_k127_5285265_9 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 286.0
SRD2_k127_5314887_0 TonB-dependent Receptor Plug Domain - - - 5.268e-280 885.0
SRD2_k127_5314887_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 6.189e-272 854.0
SRD2_k127_5314887_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 289.0
SRD2_k127_5314887_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 284.0
SRD2_k127_5314887_12 Cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001106 278.0
SRD2_k127_5314887_13 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000001649 211.0
SRD2_k127_5314887_14 protein conserved in bacteria K09973 - - 0.000000000000000000000000000000000000000000000000421 184.0
SRD2_k127_5314887_15 Transcriptional regulator K13771,K13772 - - 0.000000000000000000000000000000000000000000000002941 179.0
SRD2_k127_5314887_16 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000004862 133.0
SRD2_k127_5314887_17 - - - - 0.000000000000000000004889 98.0
SRD2_k127_5314887_2 Domain of unknown function (DUF5117) - - - 9.771e-266 842.0
SRD2_k127_5314887_3 Peptidase family M28 - - - 4.053e-219 693.0
SRD2_k127_5314887_4 Sulfotransferase family - - - 2.154e-216 683.0
SRD2_k127_5314887_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 588.0
SRD2_k127_5314887_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 521.0
SRD2_k127_5314887_7 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 387.0
SRD2_k127_5314887_8 protein conserved in bacteria K09973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 336.0
SRD2_k127_5314887_9 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 300.0
SRD2_k127_5385497_0 helicase K16899 - 3.6.4.12 0.0 1021.0
SRD2_k127_5385497_1 Phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 517.0
SRD2_k127_5385497_2 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 455.0
SRD2_k127_5385497_3 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 387.0
SRD2_k127_5385497_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000004873 222.0
SRD2_k127_5385497_5 ATPase or kinase K06925 - - 0.0000000000000000000000000000001797 128.0
SRD2_k127_551935_0 DNA helicase K03657 - 3.6.4.12 0.0 1218.0
SRD2_k127_551935_1 PilZ domain - - - 0.00000000000000000000000366 109.0
SRD2_k127_551935_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000009833 93.0
SRD2_k127_551935_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000000072 84.0
SRD2_k127_5523857_0 Transketolase, thiamine diphosphate binding domain K00163 - 1.2.4.1 0.0 1131.0
SRD2_k127_5523857_1 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 4.736e-212 668.0
SRD2_k127_5523857_10 isomerase K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003868 269.0
SRD2_k127_5523857_11 Phage shock protein A K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001693 258.0
SRD2_k127_5523857_12 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001905 246.0
SRD2_k127_5523857_13 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000001144 192.0
SRD2_k127_5523857_14 Protein of unknown function (DUF3297) - - - 0.00000000000000000000000000000000000005228 144.0
SRD2_k127_5523857_15 - - - - 0.000000000000000000000000000000000004986 144.0
SRD2_k127_5523857_16 - - - - 0.000000000000000000000000007136 111.0
SRD2_k127_5523857_17 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000000000000001138 97.0
SRD2_k127_5523857_18 - - - - 0.000000000000000002806 87.0
SRD2_k127_5523857_19 - - - - 0.00005527 51.0
SRD2_k127_5523857_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 595.0
SRD2_k127_5523857_3 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 565.0
SRD2_k127_5523857_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 460.0
SRD2_k127_5523857_5 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 388.0
SRD2_k127_5523857_6 Transcriptional regulator sugar kinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 340.0
SRD2_k127_5523857_7 cation efflux K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 319.0
SRD2_k127_5523857_8 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003251 284.0
SRD2_k127_5523857_9 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001186 269.0
SRD2_k127_5566299_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 387.0
SRD2_k127_5566299_1 Protein of unknown function (DUF3089) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 384.0
SRD2_k127_5566299_2 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 329.0
SRD2_k127_5566299_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000006735 234.0
SRD2_k127_5574925_0 Glycine dehydrogenase (aminomethyl-transferring) K00283 - 1.4.4.2 1.915e-283 880.0
SRD2_k127_5574925_1 Flp pilus assembly protein, ATPase CpaE K02282 - - 6.534e-233 724.0
SRD2_k127_5574925_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000002186 238.0
SRD2_k127_5574925_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000006484 220.0
SRD2_k127_5574925_12 Pilus assembly protein CpaD K02281 - - 0.00000000000000000000000000000000000000000000000000000000000021 225.0
SRD2_k127_5574925_13 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000004299 207.0
SRD2_k127_5574925_14 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000003904 201.0
SRD2_k127_5574925_15 Protein of unknown function (DUF1453) - - - 0.000000000000000000000000000000000000000000004101 169.0
SRD2_k127_5574925_16 peptidase K02278 - 3.4.23.43 0.00000000000000000000000000000000000000002018 158.0
SRD2_k127_5574925_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 2.163e-219 690.0
SRD2_k127_5574925_3 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 512.0
SRD2_k127_5574925_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 496.0
SRD2_k127_5574925_5 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 496.0
SRD2_k127_5574925_6 Pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 451.0
SRD2_k127_5574925_7 pilus assembly protein TadB K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 409.0
SRD2_k127_5574925_8 Oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 387.0
SRD2_k127_5574925_9 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 323.0
SRD2_k127_5605124_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 1.961e-273 851.0
SRD2_k127_5605124_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.157e-229 715.0
SRD2_k127_5605124_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008135 278.0
SRD2_k127_5605124_11 Hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001275 270.0
SRD2_k127_5605124_12 Domain of unknown function (DUF4893) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001764 257.0
SRD2_k127_5605124_13 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000002097 212.0
SRD2_k127_5605124_14 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000000000009562 196.0
SRD2_k127_5605124_15 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000003432 182.0
SRD2_k127_5605124_16 - - - - 0.00000000000000000000000000000000000006023 147.0
SRD2_k127_5605124_17 Phasin protein - - - 0.000000000000000000000000000000000005575 145.0
SRD2_k127_5605124_18 lactoylglutathione lyase activity K00941,K01724,K01759,K07032,K08234 - 2.7.1.49,2.7.4.7,4.2.1.96,4.4.1.5 0.000000000000000000000000000002352 129.0
SRD2_k127_5605124_19 -acetyltransferase K03826,K03827,K18816 - 2.3.1.82 0.000000000000000000000000001709 117.0
SRD2_k127_5605124_2 Aminotransferase K14261 - - 3.768e-207 648.0
SRD2_k127_5605124_20 membrane - - - 0.0000000000000000000006194 97.0
SRD2_k127_5605124_21 FR47-like protein - - - 0.000000000000001796 90.0
SRD2_k127_5605124_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 606.0
SRD2_k127_5605124_4 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 503.0
SRD2_k127_5605124_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 468.0
SRD2_k127_5605124_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 418.0
SRD2_k127_5605124_7 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 356.0
SRD2_k127_5605124_8 RarD protein K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 332.0
SRD2_k127_5605124_9 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
SRD2_k127_5659837_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1073.0
SRD2_k127_5659837_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.388e-305 960.0
SRD2_k127_5659837_10 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 291.0
SRD2_k127_5659837_11 cytochrome C K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003578 270.0
SRD2_k127_5659837_12 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000616 282.0
SRD2_k127_5659837_13 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 255.0
SRD2_k127_5659837_14 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000001025 227.0
SRD2_k127_5659837_15 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000000000000000000000002034 218.0
SRD2_k127_5659837_16 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000001392 206.0
SRD2_k127_5659837_17 - - - - 0.00000000000000000000000000000000000000000000000000001782 192.0
SRD2_k127_5659837_18 Thioredoxin - - - 0.000000000000000000000000000000000000000000000003394 183.0
SRD2_k127_5659837_2 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 5.554e-257 803.0
SRD2_k127_5659837_20 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404 - 1.9.3.1 0.000000000000000000000000000009395 123.0
SRD2_k127_5659837_21 response regulator K02282,K07782,K19135 - - 0.0000000000000000000000009107 111.0
SRD2_k127_5659837_22 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000000000000002946 106.0
SRD2_k127_5659837_23 amino acid peptide transporter K03305 - - 0.000000000000000000000003274 105.0
SRD2_k127_5659837_24 - - - - 0.00000000000000000001952 98.0
SRD2_k127_5659837_25 - - - - 0.0000001811 53.0
SRD2_k127_5659837_26 RES - - - 0.000002436 52.0
SRD2_k127_5659837_27 - - - - 0.0001228 47.0
SRD2_k127_5659837_3 TonB dependent receptor K16090 - - 3.028e-222 708.0
SRD2_k127_5659837_4 amino acid peptide transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 608.0
SRD2_k127_5659837_5 Inner membrane protein CreD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 440.0
SRD2_k127_5659837_6 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 429.0
SRD2_k127_5659837_7 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 387.0
SRD2_k127_5659837_8 glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 367.0
SRD2_k127_5659837_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 320.0
SRD2_k127_5677316_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1467.0
SRD2_k127_5677316_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 1.886e-218 687.0
SRD2_k127_5772131_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.331e-316 980.0
SRD2_k127_5772131_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 4.553e-227 708.0
SRD2_k127_5772131_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 287.0
SRD2_k127_5772131_11 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000001445 244.0
SRD2_k127_5772131_12 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.0000000000000000000000000000000000000000000000000000004108 198.0
SRD2_k127_5772131_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000002818 160.0
SRD2_k127_5772131_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000009812 165.0
SRD2_k127_5772131_15 Protein of unknown function (FYDLN_acid) - - - 0.00000000000000000000000000000000005128 139.0
SRD2_k127_5772131_16 - - - - 0.0000000000000000000001419 102.0
SRD2_k127_5772131_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 3.08e-200 638.0
SRD2_k127_5772131_3 Enterochelin esterase - - - 2.655e-194 619.0
SRD2_k127_5772131_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 517.0
SRD2_k127_5772131_5 PFAM alpha beta hydrolase fold K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 492.0
SRD2_k127_5772131_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 489.0
SRD2_k127_5772131_7 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 427.0
SRD2_k127_5772131_8 Serine aminopeptidase, S33 K18457 - 3.5.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 409.0
SRD2_k127_5772131_9 protein conserved in bacteria K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 311.0
SRD2_k127_583933_0 Serine carboxypeptidase - - - 7.986e-215 677.0
SRD2_k127_583933_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 1.3e-202 640.0
SRD2_k127_583933_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 329.0
SRD2_k127_583933_11 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000637 284.0
SRD2_k127_583933_12 Ferredoxin K04755 - - 0.00000000000000000000000000000000000002074 150.0
SRD2_k127_583933_13 EF hand - - - 0.000000000000000000000000000000000000763 151.0
SRD2_k127_583933_14 MAPEG family - - - 0.00000000000000000000000000000000006993 138.0
SRD2_k127_583933_2 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 2.456e-199 626.0
SRD2_k127_583933_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 561.0
SRD2_k127_583933_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 517.0
SRD2_k127_583933_5 overlaps another CDS with the same product name K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 464.0
SRD2_k127_583933_6 Alpha Beta K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 416.0
SRD2_k127_583933_7 overlaps another CDS with the same product name K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 413.0
SRD2_k127_583933_8 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 390.0
SRD2_k127_583933_9 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 339.0
SRD2_k127_5933584_0 Heat shock 70 kDa protein K04043 - - 0.0 1095.0
SRD2_k127_5933584_1 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.0 1050.0
SRD2_k127_5933584_10 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 332.0
SRD2_k127_5933584_11 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 304.0
SRD2_k127_5933584_12 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 295.0
SRD2_k127_5933584_13 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000001158 278.0
SRD2_k127_5933584_14 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005746 269.0
SRD2_k127_5933584_15 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001171 265.0
SRD2_k127_5933584_16 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000585 199.0
SRD2_k127_5933584_17 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000000006697 186.0
SRD2_k127_5933584_18 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000002828 173.0
SRD2_k127_5933584_19 Domain of unknown function (DUF4163) - - - 0.0000000000000000000000000000000000000000001946 168.0
SRD2_k127_5933584_2 Dicarboxylate transport - - - 2e-323 1022.0
SRD2_k127_5933584_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000004938 159.0
SRD2_k127_5933584_21 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000005148 160.0
SRD2_k127_5933584_22 Thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000002455 156.0
SRD2_k127_5933584_23 OsmC-like protein - - - 0.0000000000000000000000000000000000003705 143.0
SRD2_k127_5933584_24 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000002674 134.0
SRD2_k127_5933584_25 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000009841 134.0
SRD2_k127_5933584_26 light-regulated signal transduction histidine kinase - - - 0.000000000000000000000000000000249 134.0
SRD2_k127_5933584_27 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000566 114.0
SRD2_k127_5933584_28 protein conserved in bacteria K09978 - - 0.0000000000000000000001647 105.0
SRD2_k127_5933584_29 Protein of unknown function (DUF3309) - - - 0.00000000000000002437 82.0
SRD2_k127_5933584_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.389e-235 733.0
SRD2_k127_5933584_30 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000000000003413 86.0
SRD2_k127_5933584_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.353e-203 640.0
SRD2_k127_5933584_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 486.0
SRD2_k127_5933584_6 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 445.0
SRD2_k127_5933584_7 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 421.0
SRD2_k127_5933584_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 387.0
SRD2_k127_5933584_9 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 372.0
SRD2_k127_6005229_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1170.0
SRD2_k127_6005229_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1112.0
SRD2_k127_6005229_10 Belongs to the GPI family K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 9.297e-196 625.0
SRD2_k127_6005229_11 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.295e-195 620.0
SRD2_k127_6005229_12 Chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 605.0
SRD2_k127_6005229_13 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 537.0
SRD2_k127_6005229_14 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 513.0
SRD2_k127_6005229_15 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 489.0
SRD2_k127_6005229_16 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 477.0
SRD2_k127_6005229_17 amino acid transport K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 479.0
SRD2_k127_6005229_18 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 464.0
SRD2_k127_6005229_19 Polynucleotide adenylyltransferase K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 462.0
SRD2_k127_6005229_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.465e-320 987.0
SRD2_k127_6005229_20 L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 461.0
SRD2_k127_6005229_21 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 436.0
SRD2_k127_6005229_22 Glycosyltransferase Family 4 K14335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 436.0
SRD2_k127_6005229_23 Metal binding domain of Ada K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 430.0
SRD2_k127_6005229_24 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 413.0
SRD2_k127_6005229_25 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 401.0
SRD2_k127_6005229_26 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 402.0
SRD2_k127_6005229_27 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 386.0
SRD2_k127_6005229_28 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 384.0
SRD2_k127_6005229_29 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 379.0
SRD2_k127_6005229_3 TonB dependent receptor - - - 3.904e-317 998.0
SRD2_k127_6005229_30 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 356.0
SRD2_k127_6005229_31 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 351.0
SRD2_k127_6005229_32 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 336.0
SRD2_k127_6005229_33 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 337.0
SRD2_k127_6005229_34 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 334.0
SRD2_k127_6005229_35 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 320.0
SRD2_k127_6005229_36 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 332.0
SRD2_k127_6005229_37 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 307.0
SRD2_k127_6005229_38 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 304.0
SRD2_k127_6005229_39 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 302.0
SRD2_k127_6005229_4 Oxidoreductase - - - 2.613e-271 848.0
SRD2_k127_6005229_40 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 299.0
SRD2_k127_6005229_41 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 286.0
SRD2_k127_6005229_42 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002923 276.0
SRD2_k127_6005229_43 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000006378 266.0
SRD2_k127_6005229_44 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
SRD2_k127_6005229_45 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006694 259.0
SRD2_k127_6005229_46 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000002988 243.0
SRD2_k127_6005229_47 protein conserved in bacteria K09986 - - 0.00000000000000000000000000000000000000000000000000000000000000000003442 236.0
SRD2_k127_6005229_48 Nudix hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000004205 229.0
SRD2_k127_6005229_49 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000001647 225.0
SRD2_k127_6005229_5 Chloride channel protein - - - 6.58e-255 798.0
SRD2_k127_6005229_50 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000004575 206.0
SRD2_k127_6005229_51 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000006095 213.0
SRD2_k127_6005229_52 - - - - 0.00000000000000000000000000000000000000000000000000000012 199.0
SRD2_k127_6005229_53 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000000000000000002335 189.0
SRD2_k127_6005229_54 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000000000000006602 186.0
SRD2_k127_6005229_55 Biopolymer K03559 - - 0.00000000000000000000000000000000000000000000000000132 188.0
SRD2_k127_6005229_56 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000003467 175.0
SRD2_k127_6005229_57 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000001381 170.0
SRD2_k127_6005229_58 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000007929 164.0
SRD2_k127_6005229_59 Acetyltransferase (GNAT) domain K03829 - - 0.0000000000000000000000000000000000000000006356 161.0
SRD2_k127_6005229_6 GGDEF domain - - - 6.114e-251 786.0
SRD2_k127_6005229_60 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000009149 139.0
SRD2_k127_6005229_61 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000001572 145.0
SRD2_k127_6005229_62 Thioesterase superfamily - - - 0.0000000000000000000000000000000004443 136.0
SRD2_k127_6005229_63 - - - - 0.000000000000000000000000000006659 130.0
SRD2_k127_6005229_64 NlpC/P60 family - - - 0.0000000000000000000001516 103.0
SRD2_k127_6005229_66 TadE-like protein - - - 0.0000000000000000002 94.0
SRD2_k127_6005229_67 Flp pilus assembly protein, pilin Flp K02651 - - 0.000000000000001908 78.0
SRD2_k127_6005229_68 Belongs to the peptidase S1C family K04771,K04772,K08070 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 1.3.1.74,3.4.21.107 0.0000000000002076 81.0
SRD2_k127_6005229_69 TadE-like protein - - - 0.0000000000009954 79.0
SRD2_k127_6005229_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.277e-246 762.0
SRD2_k127_6005229_70 Histidine kinase - - - 0.000000576 63.0
SRD2_k127_6005229_8 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 2.071e-211 664.0
SRD2_k127_6005229_9 Toxic anion resistance - - - 5.186e-197 620.0
SRD2_k127_6098011_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1353.0
SRD2_k127_6098011_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.922e-315 977.0
SRD2_k127_6098011_10 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 418.0
SRD2_k127_6098011_11 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 401.0
SRD2_k127_6098011_12 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 401.0
SRD2_k127_6098011_13 - K18546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 355.0
SRD2_k127_6098011_14 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 338.0
SRD2_k127_6098011_15 Phage shock protein A K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 310.0
SRD2_k127_6098011_16 Histidine phosphotransferase C-terminal domain K13588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 308.0
SRD2_k127_6098011_17 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003917 270.0
SRD2_k127_6098011_18 Trypsin-like peptidase domain K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000002796 253.0
SRD2_k127_6098011_19 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000185 246.0
SRD2_k127_6098011_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.179e-219 696.0
SRD2_k127_6098011_20 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005927 237.0
SRD2_k127_6098011_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000168 228.0
SRD2_k127_6098011_22 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000001109 214.0
SRD2_k127_6098011_23 SufE protein probably involved in Fe-S center assembly K02426 - - 0.00000000000000000000000000000000000000000000000000000000001815 208.0
SRD2_k127_6098011_24 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000002004 209.0
SRD2_k127_6098011_25 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
SRD2_k127_6098011_26 PspC domain K03973 - - 0.000000000000000000000000000000000000000000000001852 179.0
SRD2_k127_6098011_27 - K03832 - - 0.000000000000000000000000000000000000000006807 164.0
SRD2_k127_6098011_28 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000006091 146.0
SRD2_k127_6098011_29 - - - - 0.0000000000000000000000000000000000001818 149.0
SRD2_k127_6098011_3 methyl-accepting chemotaxis protein K03406 - - 3.564e-217 682.0
SRD2_k127_6098011_30 Phage shock protein B K03970 - - 0.0000000000000000000000000000001169 125.0
SRD2_k127_6098011_31 - - - - 0.0000000000000000000000000004593 118.0
SRD2_k127_6098011_32 - - - - 0.00000000000000000000000002606 112.0
SRD2_k127_6098011_34 - - - - 0.00000000000000001528 90.0
SRD2_k127_6098011_35 PspC domain protein - - - 0.000000000000006771 77.0
SRD2_k127_6098011_37 - - - - 0.00000000001249 68.0
SRD2_k127_6098011_38 - - - - 0.00000000003061 69.0
SRD2_k127_6098011_4 Protein of unknown function (DUF1343) - - - 1.129e-213 668.0
SRD2_k127_6098011_40 - - - - 0.00000296 56.0
SRD2_k127_6098011_41 Protein of unknown function (DUF3761) - - - 0.00000599 56.0
SRD2_k127_6098011_42 - - - - 0.00004131 49.0
SRD2_k127_6098011_5 chemotaxis protein K03407 - 2.7.13.3 1.853e-211 681.0
SRD2_k127_6098011_6 Belongs to the CarA family K01956 - 6.3.5.5 2.091e-196 617.0
SRD2_k127_6098011_7 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 532.0
SRD2_k127_6098011_8 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain K03974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 522.0
SRD2_k127_6098011_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 481.0
SRD2_k127_6117039_0 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0 1010.0
SRD2_k127_6117039_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000004209 150.0
SRD2_k127_6117039_3 SnoaL-like domain K06893 - - 0.000000000000000000000000000001699 124.0
SRD2_k127_6161156_0 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 525.0
SRD2_k127_6161156_1 alcohol dehydrogenase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 465.0
SRD2_k127_6161156_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 377.0
SRD2_k127_6161156_3 metalloprotease K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 327.0
SRD2_k127_6161156_4 Domain of unknown function (DUF4893) - - - 0.0000000000000000000000000000000000000000000000005461 189.0
SRD2_k127_6161156_5 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000005939 172.0
SRD2_k127_6161156_6 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.00000000000000000000000000000000000000000000218 177.0
SRD2_k127_6161156_7 - - - - 0.0000000625 63.0
SRD2_k127_6217408_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1338.0
SRD2_k127_6217408_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1289.0
SRD2_k127_6217408_10 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 606.0
SRD2_k127_6217408_11 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 588.0
SRD2_k127_6217408_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 566.0
SRD2_k127_6217408_13 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 493.0
SRD2_k127_6217408_14 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 475.0
SRD2_k127_6217408_15 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 469.0
SRD2_k127_6217408_16 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 452.0
SRD2_k127_6217408_17 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 435.0
SRD2_k127_6217408_18 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 427.0
SRD2_k127_6217408_19 beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 426.0
SRD2_k127_6217408_2 DNA segregation ATPase FtsK SpoIIIE K03466 - - 4.253e-302 944.0
SRD2_k127_6217408_20 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 397.0
SRD2_k127_6217408_21 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 396.0
SRD2_k127_6217408_22 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 391.0
SRD2_k127_6217408_23 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 356.0
SRD2_k127_6217408_24 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 349.0
SRD2_k127_6217408_25 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 328.0
SRD2_k127_6217408_26 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 321.0
SRD2_k127_6217408_27 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003417 281.0
SRD2_k127_6217408_28 DNA polymerase III K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008517 284.0
SRD2_k127_6217408_29 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006033 261.0
SRD2_k127_6217408_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 5.848e-283 879.0
SRD2_k127_6217408_30 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000903 260.0
SRD2_k127_6217408_31 to the N-terminal domain of Lon protease K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006772 253.0
SRD2_k127_6217408_32 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007767 252.0
SRD2_k127_6217408_33 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003327 261.0
SRD2_k127_6217408_34 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001674 238.0
SRD2_k127_6217408_35 Domain of unknown function (DUF3576) - - - 0.0000000000000000000000000000000000000000000000000000000001459 206.0
SRD2_k127_6217408_36 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000622 198.0
SRD2_k127_6217408_37 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000001663 196.0
SRD2_k127_6217408_38 Lipopolysaccharide-assembly K03643 - - 0.0000000000000000000000000000000000000000000000000005068 190.0
SRD2_k127_6217408_39 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000001694 195.0
SRD2_k127_6217408_4 Peptidase family M3 K01284 - 3.4.15.5 3.674e-274 862.0
SRD2_k127_6217408_40 membrane - - - 0.00000000000000000000000000000000000000000000000006569 181.0
SRD2_k127_6217408_41 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000001691 196.0
SRD2_k127_6217408_42 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000216 166.0
SRD2_k127_6217408_43 protein conserved in bacteria - - - 0.0000000000000000000000000000000005277 134.0
SRD2_k127_6217408_44 - - - - 0.000000000000000000000000001014 125.0
SRD2_k127_6217408_45 Domain of unknown function (DUF4402) - - - 0.0000000000000000000000005272 110.0
SRD2_k127_6217408_46 protein conserved in bacteria - - - 0.000000000000000000000004356 102.0
SRD2_k127_6217408_47 Domain of unknown function (DUF4402) - - - 0.00000000000000000001195 98.0
SRD2_k127_6217408_48 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000004369 92.0
SRD2_k127_6217408_49 - - - - 0.0000000000000003878 81.0
SRD2_k127_6217408_5 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase K06147 - - 1.699e-258 810.0
SRD2_k127_6217408_51 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000002519 81.0
SRD2_k127_6217408_54 Putative prokaryotic signal transducing protein - - - 0.000003341 55.0
SRD2_k127_6217408_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.147e-254 797.0
SRD2_k127_6217408_7 peptidase U62, modulator of DNA gyrase K03568 - - 3e-237 742.0
SRD2_k127_6217408_8 Heparinase - - - 5.792e-228 725.0
SRD2_k127_6217408_9 Glycosyl hydrolase family 47 - - - 7.914e-197 625.0
SRD2_k127_6303307_0 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 7.871e-198 641.0
SRD2_k127_6303307_1 COG1253 Hemolysins and related proteins containing CBS domains K03699 - - 1.609e-196 627.0
SRD2_k127_6303307_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 604.0
SRD2_k127_6303307_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 597.0
SRD2_k127_6303307_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000006269 216.0
SRD2_k127_6303307_5 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000005778 169.0
SRD2_k127_6303307_6 NADH ubiquinone oxidoreductase 41 kD complex I subunit - - - 0.000000000000000000000000000000000001497 143.0
SRD2_k127_6303307_7 - - - - 0.00000000000000000000000000001791 124.0
SRD2_k127_6303307_8 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.000000000000000000000003352 106.0
SRD2_k127_6431608_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.521e-236 735.0
SRD2_k127_6431608_1 argininosuccinate lyase K01755 - 4.3.2.1 2.567e-212 668.0
SRD2_k127_6431608_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 442.0
SRD2_k127_6431608_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 363.0
SRD2_k127_6431608_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 295.0
SRD2_k127_6435240_0 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 8.025e-262 817.0
SRD2_k127_6435240_1 Oxidoreductase - - - 1.875e-258 808.0
SRD2_k127_6435240_2 Dehydrogenase K00101 - 1.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 423.0
SRD2_k127_6435240_3 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002805 234.0
SRD2_k127_6435240_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000002907 228.0
SRD2_k127_6451154_0 peptidase M13 - - - 2.5e-323 1007.0
SRD2_k127_6451154_1 peptidase M13 - - - 7.441e-268 839.0
SRD2_k127_6451154_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 349.0
SRD2_k127_6451154_3 Histidine kinase - - - 0.0000000000000000000000000000000000000004828 149.0
SRD2_k127_6543955_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 584.0
SRD2_k127_6543955_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 483.0
SRD2_k127_6543955_2 Prolyl 4-hydroxylase alpha subunit homologues. K07336 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 285.0
SRD2_k127_6543955_3 - - - - 0.000000000000000006006 89.0
SRD2_k127_6553364_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 571.0
SRD2_k127_6553364_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 461.0
SRD2_k127_6553364_2 Putative S-adenosyl-L-methionine-dependent methyltransferase K18164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 362.0
SRD2_k127_6553364_3 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007273 276.0
SRD2_k127_6553364_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000007053 202.0
SRD2_k127_6553364_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000004247 192.0
SRD2_k127_6607233_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1240.0
SRD2_k127_6607233_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000001433 149.0
SRD2_k127_6607233_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000004188 158.0
SRD2_k127_6607233_3 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000009078 107.0
SRD2_k127_6607233_4 Isochorismatase family - - - 0.0000000000000007507 81.0
SRD2_k127_6615343_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1007.0
SRD2_k127_6615343_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.571e-299 924.0
SRD2_k127_6615343_10 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 571.0
SRD2_k127_6615343_11 peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 563.0
SRD2_k127_6615343_12 DNA recombination protein K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 549.0
SRD2_k127_6615343_13 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 526.0
SRD2_k127_6615343_14 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 509.0
SRD2_k127_6615343_15 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 494.0
SRD2_k127_6615343_16 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 473.0
SRD2_k127_6615343_17 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 464.0
SRD2_k127_6615343_18 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 448.0
SRD2_k127_6615343_19 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 410.0
SRD2_k127_6615343_2 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.081e-288 906.0
SRD2_k127_6615343_20 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 408.0
SRD2_k127_6615343_21 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 396.0
SRD2_k127_6615343_22 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 390.0
SRD2_k127_6615343_23 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 371.0
SRD2_k127_6615343_24 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 376.0
SRD2_k127_6615343_25 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 361.0
SRD2_k127_6615343_26 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 368.0
SRD2_k127_6615343_27 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 343.0
SRD2_k127_6615343_28 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005013 284.0
SRD2_k127_6615343_29 ATPase involved in DNA replication - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000429 283.0
SRD2_k127_6615343_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 7.154e-288 891.0
SRD2_k127_6615343_30 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000702 255.0
SRD2_k127_6615343_31 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002713 254.0
SRD2_k127_6615343_32 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000008902 250.0
SRD2_k127_6615343_33 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006315 246.0
SRD2_k127_6615343_34 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000001327 244.0
SRD2_k127_6615343_35 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000002681 221.0
SRD2_k127_6615343_36 PTS fructose transporter subunit IIA K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000000000000001345 215.0
SRD2_k127_6615343_37 Serine kinase of the HPr protein, regulates carbohydrate metabolism - - - 0.00000000000000000000000000000000000000000000000000000000127 204.0
SRD2_k127_6615343_38 DNA polymerase III K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000002963 196.0
SRD2_k127_6615343_39 - - - - 0.0000000000000000000000000000000000000000000000000000235 191.0
SRD2_k127_6615343_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.095e-254 791.0
SRD2_k127_6615343_40 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000002924 185.0
SRD2_k127_6615343_41 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.0000000000000000000000000000000000000000000959 162.0
SRD2_k127_6615343_42 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000002744 150.0
SRD2_k127_6615343_43 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000000002757 137.0
SRD2_k127_6615343_44 protein conserved in bacteria K09928 - - 0.00000000000000000000000000003246 123.0
SRD2_k127_6615343_45 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.00000000000000000000000000483 119.0
SRD2_k127_6615343_46 Preprotein translocase subunit SecG K03075 - - 0.000000000000000000000000008027 114.0
SRD2_k127_6615343_48 - - - - 0.00000000003453 64.0
SRD2_k127_6615343_49 - - - - 0.00000001255 63.0
SRD2_k127_6615343_5 Protein conserved in bacteria - - - 1.354e-224 715.0
SRD2_k127_6615343_50 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000002521 56.0
SRD2_k127_6615343_6 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 3.019e-207 651.0
SRD2_k127_6615343_7 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 8.42e-205 657.0
SRD2_k127_6615343_8 Histidine kinase K14980 - 2.7.13.3 4.397e-198 632.0
SRD2_k127_6615343_9 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 585.0
SRD2_k127_6665120_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 3.804e-292 914.0
SRD2_k127_6665120_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.392e-224 704.0
SRD2_k127_6665120_10 COG3773 Cell wall hydrolyses involved in spore germination - - - 0.00000000000000000000000000000000000003299 153.0
SRD2_k127_6665120_11 - - - - 0.000000000003569 74.0
SRD2_k127_6665120_12 Protein of unknown function (DUF3828) - - - 0.000000001329 67.0
SRD2_k127_6665120_2 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 600.0
SRD2_k127_6665120_3 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 384.0
SRD2_k127_6665120_4 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 372.0
SRD2_k127_6665120_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000002524 221.0
SRD2_k127_6665120_6 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.0000000000000000000000000000000000000000000000000000000000009803 214.0
SRD2_k127_6665120_7 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000005569 199.0
SRD2_k127_6665120_8 EVE domain - - - 0.000000000000000000000000000000000000000000000000002884 188.0
SRD2_k127_6665120_9 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000004908 166.0
SRD2_k127_6682566_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0 1036.0
SRD2_k127_6682566_1 GTP-binding protein TypA K06207 - - 3.836e-261 812.0
SRD2_k127_6682566_10 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000001982 228.0
SRD2_k127_6682566_11 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000005284 138.0
SRD2_k127_6682566_12 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000296 131.0
SRD2_k127_6682566_13 Zinc-finger domain - - - 0.000000000000000000001102 96.0
SRD2_k127_6682566_14 - - - - 0.000000000000000001058 87.0
SRD2_k127_6682566_15 - - - - 0.0000000000005036 74.0
SRD2_k127_6682566_16 COG3668 Plasmid stabilization system protein - - - 0.0000000001587 63.0
SRD2_k127_6682566_18 - - - - 0.000000003705 68.0
SRD2_k127_6682566_19 - - - - 0.00000002535 55.0
SRD2_k127_6682566_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 490.0
SRD2_k127_6682566_20 - - - - 0.00005907 49.0
SRD2_k127_6682566_22 Regulatory protein MarR - - - 0.0001119 52.0
SRD2_k127_6682566_23 Cold shock K03704 - - 0.0003521 45.0
SRD2_k127_6682566_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 442.0
SRD2_k127_6682566_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 436.0
SRD2_k127_6682566_5 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 372.0
SRD2_k127_6682566_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 375.0
SRD2_k127_6682566_7 COG1538 Outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 384.0
SRD2_k127_6682566_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001013 252.0
SRD2_k127_6682566_9 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000002601 244.0
SRD2_k127_6708918_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1467.0
SRD2_k127_6708918_1 amino acid K03294 - - 2.932e-259 809.0
SRD2_k127_6708918_10 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 351.0
SRD2_k127_6708918_11 Binding-protein-dependent transport system inner membrane component K02038 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 349.0
SRD2_k127_6708918_12 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 359.0
SRD2_k127_6708918_13 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 350.0
SRD2_k127_6708918_14 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 312.0
SRD2_k127_6708918_15 COG2513 PEP phosphonomutase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
SRD2_k127_6708918_16 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005705 240.0
SRD2_k127_6708918_17 protein conserved in bacteria K09985 - - 0.0000000000000000000000000000000000000000000000000000000000000003089 224.0
SRD2_k127_6708918_18 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000005559 215.0
SRD2_k127_6708918_19 Protein of unknown function (DUF2585) - - - 0.000000000000000000000000000000000000000000000000000000003379 204.0
SRD2_k127_6708918_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 4.015e-206 649.0
SRD2_k127_6708918_20 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000000000000000000000000000000007896 200.0
SRD2_k127_6708918_21 Aminomethyltransferase K06980 - - 0.0000000000000000000002443 98.0
SRD2_k127_6708918_22 - - - - 0.00000000000000000001579 95.0
SRD2_k127_6708918_23 - - - - 0.0000000000000000008822 91.0
SRD2_k127_6708918_24 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000002798 92.0
SRD2_k127_6708918_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 486.0
SRD2_k127_6708918_4 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 457.0
SRD2_k127_6708918_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 436.0
SRD2_k127_6708918_6 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 424.0
SRD2_k127_6708918_7 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 398.0
SRD2_k127_6708918_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 378.0
SRD2_k127_6708918_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 359.0
SRD2_k127_6739347_0 Putative glucoamylase - - - 8.036e-232 734.0
SRD2_k127_6739347_1 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000003368 181.0
SRD2_k127_6739347_2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.000000000000000000007046 94.0
SRD2_k127_6742928_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1162.0
SRD2_k127_6742928_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 7.102e-301 929.0
SRD2_k127_6742928_10 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 456.0
SRD2_k127_6742928_11 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 443.0
SRD2_k127_6742928_12 molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 437.0
SRD2_k127_6742928_13 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 412.0
SRD2_k127_6742928_14 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 356.0
SRD2_k127_6742928_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 325.0
SRD2_k127_6742928_16 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 297.0
SRD2_k127_6742928_17 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001358 277.0
SRD2_k127_6742928_18 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000341 256.0
SRD2_k127_6742928_19 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000000000000004523 233.0
SRD2_k127_6742928_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 3.92e-248 776.0
SRD2_k127_6742928_20 Hpt domain K20976 - - 0.00000000000000000000000000000000000000000000000000000000000000002067 227.0
SRD2_k127_6742928_21 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000005107 211.0
SRD2_k127_6742928_22 Glyoxalase-like domain K04750 - - 0.0000000000000000000000000000000000000000000000000000000002141 208.0
SRD2_k127_6742928_23 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000002131 194.0
SRD2_k127_6742928_24 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000007032 181.0
SRD2_k127_6742928_25 - - - - 0.0000000000000000000000000000000000000000000006477 169.0
SRD2_k127_6742928_26 Belongs to the HesB IscA family - - - 0.000000000000000000000000000000000000000003699 159.0
SRD2_k127_6742928_27 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000115 92.0
SRD2_k127_6742928_28 BFD-like [2Fe-2S] binding domain K02192 - - 0.00000000000004836 73.0
SRD2_k127_6742928_29 - - - - 0.000004233 60.0
SRD2_k127_6742928_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.492e-235 732.0
SRD2_k127_6742928_30 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.00001191 54.0
SRD2_k127_6742928_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 9.963e-224 700.0
SRD2_k127_6742928_5 Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 551.0
SRD2_k127_6742928_6 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 544.0
SRD2_k127_6742928_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 527.0
SRD2_k127_6742928_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 463.0
SRD2_k127_6742928_9 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 465.0
SRD2_k127_6758690_0 asparagine synthase K01953 - 6.3.5.4 1.686e-194 626.0
SRD2_k127_6758690_1 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 616.0
SRD2_k127_6758690_10 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 356.0
SRD2_k127_6758690_11 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001094 284.0
SRD2_k127_6758690_12 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001834 286.0
SRD2_k127_6758690_13 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003213 259.0
SRD2_k127_6758690_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001544 250.0
SRD2_k127_6758690_15 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000005809 249.0
SRD2_k127_6758690_16 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.0000000000000000000000000000000000000000000000000000000000000000004058 241.0
SRD2_k127_6758690_17 response regulator K13589 - - 0.000000000000000000000000000000000000000000000000000000000000000008281 226.0
SRD2_k127_6758690_18 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000309 210.0
SRD2_k127_6758690_19 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000001618 211.0
SRD2_k127_6758690_2 Belongs to the DEAD box helicase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 601.0
SRD2_k127_6758690_20 Glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000002014 209.0
SRD2_k127_6758690_22 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000008169 189.0
SRD2_k127_6758690_23 - - - - 0.000000000000000000000000000000000000006109 153.0
SRD2_k127_6758690_24 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000004534 117.0
SRD2_k127_6758690_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 589.0
SRD2_k127_6758690_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 520.0
SRD2_k127_6758690_5 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 482.0
SRD2_k127_6758690_6 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 460.0
SRD2_k127_6758690_7 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 436.0
SRD2_k127_6758690_8 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 417.0
SRD2_k127_6758690_9 PFAM SapC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 372.0
SRD2_k127_6784360_0 alcohol dehydrogenase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 466.0
SRD2_k127_6784360_1 metalloprotease K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001638 250.0
SRD2_k127_6784360_2 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.0000000000000000000000000000000000000000000000001026 191.0
SRD2_k127_6873377_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 9.619e-271 843.0
SRD2_k127_6873377_1 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 1.112e-242 764.0
SRD2_k127_6873377_10 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 502.0
SRD2_k127_6873377_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 512.0
SRD2_k127_6873377_12 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 454.0
SRD2_k127_6873377_13 dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 415.0
SRD2_k127_6873377_14 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 394.0
SRD2_k127_6873377_15 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 329.0
SRD2_k127_6873377_16 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 313.0
SRD2_k127_6873377_17 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
SRD2_k127_6873377_18 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000004153 237.0
SRD2_k127_6873377_19 dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000001088 147.0
SRD2_k127_6873377_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.151e-232 739.0
SRD2_k127_6873377_20 - - - - 0.00000000000000000000000000000009232 136.0
SRD2_k127_6873377_21 - - - - 0.000000000000000000000001047 107.0
SRD2_k127_6873377_22 Cold-shock protein K03704 - - 0.00000000000000000000006356 100.0
SRD2_k127_6873377_23 PilZ domain - - - 0.0000000009285 67.0
SRD2_k127_6873377_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.067e-216 679.0
SRD2_k127_6873377_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 2.683e-215 676.0
SRD2_k127_6873377_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 604.0
SRD2_k127_6873377_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 601.0
SRD2_k127_6873377_7 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 592.0
SRD2_k127_6873377_8 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 528.0
SRD2_k127_6873377_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 533.0
SRD2_k127_696347_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1087.0
SRD2_k127_696347_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.175e-250 779.0
SRD2_k127_696347_2 5-aminolevulinic acid synthase K00643 - 2.3.1.37 2.512e-217 678.0
SRD2_k127_696347_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 344.0
SRD2_k127_696347_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000177 252.0
SRD2_k127_696347_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000002991 235.0
SRD2_k127_696347_6 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000001684 220.0
SRD2_k127_696347_7 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000001318 170.0
SRD2_k127_696347_8 Sulfotransferase domain - - - 0.000000000000000000000000000000000008008 148.0
SRD2_k127_6976090_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1518.0
SRD2_k127_6976090_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1031.0
SRD2_k127_6976090_2 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 603.0
SRD2_k127_6976090_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 392.0
SRD2_k127_6976090_4 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 356.0
SRD2_k127_6976090_5 protein involved in formation of curli polymers - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 352.0
SRD2_k127_7011506_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1437.0
SRD2_k127_7011506_1 Glycosyl hydrolase family 92 - - - 0.0 1220.0
SRD2_k127_7011506_10 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009922 391.0
SRD2_k127_7011506_11 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 379.0
SRD2_k127_7011506_12 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 356.0
SRD2_k127_7011506_13 Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 335.0
SRD2_k127_7011506_14 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002562 277.0
SRD2_k127_7011506_15 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000583 276.0
SRD2_k127_7011506_16 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000002232 263.0
SRD2_k127_7011506_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000007607 231.0
SRD2_k127_7011506_18 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000000000000000000002 229.0
SRD2_k127_7011506_19 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000003043 218.0
SRD2_k127_7011506_2 Transporter - - - 5.417e-273 856.0
SRD2_k127_7011506_20 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000003755 212.0
SRD2_k127_7011506_21 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000006312 211.0
SRD2_k127_7011506_22 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000006944 201.0
SRD2_k127_7011506_23 Predicted membrane protein (DUF2127) - - - 0.0000000000000000000000000000000000000000000000000000007271 198.0
SRD2_k127_7011506_24 small integral membrane protein - - - 0.0000000000000000000000000000000000000000000000006489 180.0
SRD2_k127_7011506_25 Protein of unknown function (DUF3035) - - - 0.00000000000000000000000000000000147 134.0
SRD2_k127_7011506_26 acyl carrier protein - - - 0.0000000000000000000000000000008289 123.0
SRD2_k127_7011506_29 - - - - 0.0000001728 54.0
SRD2_k127_7011506_3 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes K00639,K00652 - 2.3.1.29,2.3.1.47 4.325e-223 695.0
SRD2_k127_7011506_30 Bacterial transcriptional repressor C-terminal - - - 0.000001894 53.0
SRD2_k127_7011506_31 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0009972 48.0
SRD2_k127_7011506_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 1.091e-195 614.0
SRD2_k127_7011506_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 593.0
SRD2_k127_7011506_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 499.0
SRD2_k127_7011506_7 YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 496.0
SRD2_k127_7011506_8 YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 436.0
SRD2_k127_7011506_9 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 385.0
SRD2_k127_7048927_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1146.0
SRD2_k127_7048927_1 acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 1.551e-311 966.0
SRD2_k127_7048927_2 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001 248.0
SRD2_k127_7048927_3 conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000002123 215.0
SRD2_k127_7048927_4 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000001971 177.0
SRD2_k127_7059992_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.543e-243 761.0
SRD2_k127_7059992_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 1.539e-197 638.0
SRD2_k127_7059992_10 MazG family K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 287.0
SRD2_k127_7059992_11 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000000000000000004921 239.0
SRD2_k127_7059992_12 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000001119 215.0
SRD2_k127_7059992_13 Penicillinase repressor - - - 0.000000000000000000000000000000000000000000000003165 175.0
SRD2_k127_7059992_14 Resolvase, N terminal domain - - - 0.00000000001131 66.0
SRD2_k127_7059992_16 IS116 IS110 IS902 family K07486 - - 0.0000006305 55.0
SRD2_k127_7059992_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 550.0
SRD2_k127_7059992_3 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 436.0
SRD2_k127_7059992_4 Lytic murein transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 397.0
SRD2_k127_7059992_5 LuxR family transcriptional regulator K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 387.0
SRD2_k127_7059992_6 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 358.0
SRD2_k127_7059992_7 DNA polymerase K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 351.0
SRD2_k127_7059992_8 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
SRD2_k127_7059992_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 299.0
SRD2_k127_7101084_0 Peptidase, M16 - - - 0.0 1058.0
SRD2_k127_7101084_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 445.0
SRD2_k127_7101084_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000003352 248.0
SRD2_k127_7101084_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000003365 198.0
SRD2_k127_7101084_4 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000002365 181.0
SRD2_k127_7101084_5 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000006579 147.0
SRD2_k127_7267333_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.489e-317 977.0
SRD2_k127_7267333_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 565.0
SRD2_k127_7267333_10 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 400.0
SRD2_k127_7267333_11 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 379.0
SRD2_k127_7267333_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 361.0
SRD2_k127_7267333_13 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 357.0
SRD2_k127_7267333_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 304.0
SRD2_k127_7267333_15 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001406 263.0
SRD2_k127_7267333_16 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009871 245.0
SRD2_k127_7267333_17 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000001951 236.0
SRD2_k127_7267333_18 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000000000001349 228.0
SRD2_k127_7267333_19 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.00000000000000000000000000000000000000000000000000000000000004432 221.0
SRD2_k127_7267333_2 Carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 509.0
SRD2_k127_7267333_20 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000000000004517 215.0
SRD2_k127_7267333_21 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000001578 212.0
SRD2_k127_7267333_22 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000001039 198.0
SRD2_k127_7267333_23 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000008002 192.0
SRD2_k127_7267333_24 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000001415 188.0
SRD2_k127_7267333_25 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000001579 151.0
SRD2_k127_7267333_26 - - - - 0.000000000000000000000000000000008412 132.0
SRD2_k127_7267333_27 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000001374 115.0
SRD2_k127_7267333_29 Transglycosylase associated protein - - - 0.0000000000000000006303 89.0
SRD2_k127_7267333_3 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 489.0
SRD2_k127_7267333_30 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.00000000000000002734 91.0
SRD2_k127_7267333_32 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000002951 79.0
SRD2_k127_7267333_33 - - - - 0.000000000004093 72.0
SRD2_k127_7267333_34 PilZ domain - - - 0.0000000005971 63.0
SRD2_k127_7267333_35 protein conserved in bacteria - - - 0.0000000214 55.0
SRD2_k127_7267333_36 - - - - 0.00009942 49.0
SRD2_k127_7267333_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 471.0
SRD2_k127_7267333_5 protein conserved in bacteria K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 475.0
SRD2_k127_7267333_6 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 450.0
SRD2_k127_7267333_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 421.0
SRD2_k127_7267333_8 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 421.0
SRD2_k127_7267333_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 408.0
SRD2_k127_7282275_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 3.766e-221 692.0
SRD2_k127_7282275_1 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 499.0
SRD2_k127_7282275_2 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 324.0
SRD2_k127_7282275_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000005708 204.0
SRD2_k127_7282275_4 Glycine dehydrogenase (aminomethyl-transferring) K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000002654 160.0
SRD2_k127_7289170_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1024.0
SRD2_k127_7289170_1 amino acid peptide transporter K03305 - - 6.069e-286 890.0
SRD2_k127_7289170_10 NAD(P) transhydrogenase subunit alpha K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 535.0
SRD2_k127_7289170_11 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 531.0
SRD2_k127_7289170_12 dihydropteroate synthase K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 455.0
SRD2_k127_7289170_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
SRD2_k127_7289170_14 aspartate racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 312.0
SRD2_k127_7289170_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 307.0
SRD2_k127_7289170_16 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 305.0
SRD2_k127_7289170_17 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 286.0
SRD2_k127_7289170_18 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007373 282.0
SRD2_k127_7289170_19 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000964 285.0
SRD2_k127_7289170_2 protein involved in exopolysaccharide biosynthesis - - - 3.379e-242 770.0
SRD2_k127_7289170_20 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
SRD2_k127_7289170_21 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005744 233.0
SRD2_k127_7289170_22 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000005738 226.0
SRD2_k127_7289170_23 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000004398 190.0
SRD2_k127_7289170_24 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000004573 189.0
SRD2_k127_7289170_25 Transcriptional regulator K07979 - - 0.000000000000000000000000000000000000000000000009686 173.0
SRD2_k127_7289170_26 YbaK prolyl-tRNA synthetase associated - - - 0.0000000000000000000000000000000000000000000005221 173.0
SRD2_k127_7289170_27 nad(P) transhydrogenase subunit alpha K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000001249 163.0
SRD2_k127_7289170_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.726e-239 748.0
SRD2_k127_7289170_4 amidohydrolase - - - 2.323e-221 696.0
SRD2_k127_7289170_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.946e-219 689.0
SRD2_k127_7289170_6 Putative diguanylate phosphodiesterase - - - 3.649e-219 703.0
SRD2_k127_7289170_7 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 1.234e-204 647.0
SRD2_k127_7289170_8 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 602.0
SRD2_k127_7289170_9 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 594.0
SRD2_k127_7292533_0 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000001046 227.0
SRD2_k127_7292533_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000008805 225.0
SRD2_k127_7292533_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000001357 187.0
SRD2_k127_7292533_3 - - - - 0.00000000000000000000816 97.0
SRD2_k127_7296867_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.749e-310 966.0
SRD2_k127_7296867_1 Methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 3.851e-294 908.0
SRD2_k127_7296867_10 COG1734 DnaK suppressor protein - - - 0.0000000000000000000000000000000000001625 142.0
SRD2_k127_7296867_11 - - - - 0.0000000000000001279 86.0
SRD2_k127_7296867_12 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000005273 68.0
SRD2_k127_7296867_13 - - - - 0.000004605 53.0
SRD2_k127_7296867_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 2.994e-212 663.0
SRD2_k127_7296867_3 Peptidase, M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 604.0
SRD2_k127_7296867_4 enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 494.0
SRD2_k127_7296867_5 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 444.0
SRD2_k127_7296867_6 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009796 264.0
SRD2_k127_7296867_7 NAD(P)H-dependent FMN reductase K19784 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006805,GO:0008150,GO:0008152,GO:0009410,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0032553,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0052873,GO:0055114,GO:0070887,GO:0071466,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000001216 219.0
SRD2_k127_7296867_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000002521 192.0
SRD2_k127_7296867_9 DoxX K15977 - - 0.0000000000000000000000000000000000000354 147.0
SRD2_k127_7347486_0 Belongs to the transketolase family K00615 - 2.2.1.1 1.717e-293 912.0
SRD2_k127_7347486_1 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000001154 166.0
SRD2_k127_7347486_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000005361 130.0
SRD2_k127_7347486_3 PAS domain - - - 0.0000000000000000006981 100.0
SRD2_k127_7347486_4 PilZ domain - - - 0.000000008267 63.0
SRD2_k127_7390430_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit - - - 2.821e-214 671.0
SRD2_k127_7390430_1 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 595.0
SRD2_k127_7390430_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 550.0
SRD2_k127_7390430_3 Protein of unknown function (DUF3297) - - - 0.0000000000000000000000000000000000000004475 150.0
SRD2_k127_7390430_4 Phage shock protein A K03969 - - 0.0000000001549 65.0
SRD2_k127_742877_0 Amidohydrolase family - - - 0.0 1152.0
SRD2_k127_742877_1 Peptidase family M13 K07386 - - 0.0 1016.0
SRD2_k127_742877_10 Methanol dehydrogenase K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002049 281.0
SRD2_k127_742877_11 Nudix hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000196 202.0
SRD2_k127_742877_12 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000005059 191.0
SRD2_k127_742877_13 membrane K08988 - - 0.000000000000000000000000000000000000000000000000001718 197.0
SRD2_k127_742877_14 - - - - 0.00000000000000000000000000000000000000000009976 171.0
SRD2_k127_742877_15 rhamnose metabolic process - - - 0.0000000000000000000000000000000000002792 142.0
SRD2_k127_742877_16 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000001341 143.0
SRD2_k127_742877_2 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 8.064e-297 920.0
SRD2_k127_742877_20 phospholipase Carboxylesterase K06999 - - 0.0006697 45.0
SRD2_k127_742877_3 acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 7.946e-291 909.0
SRD2_k127_742877_4 2-nitropropane dioxygenase - - - 4.863e-279 861.0
SRD2_k127_742877_5 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 3.5e-213 668.0
SRD2_k127_742877_6 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 578.0
SRD2_k127_742877_7 Belongs to the NadC ModD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 403.0
SRD2_k127_742877_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 362.0
SRD2_k127_742877_9 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 303.0
SRD2_k127_7436804_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1470.0
SRD2_k127_7436804_1 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 364.0
SRD2_k127_7436804_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 307.0
SRD2_k127_7436804_3 Protein of unknown function (DUF2585) - - - 0.0000000000000000000000000000000000000000000000000000000000001127 226.0
SRD2_k127_7436804_4 - - - - 0.000000000000000000000001819 106.0
SRD2_k127_7436804_5 Aminomethyltransferase K06980 - - 0.00000000000006646 73.0
SRD2_k127_7522444_0 amine dehydrogenase activity - - - 0.0 1317.0
SRD2_k127_7522444_1 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1138.0
SRD2_k127_7522444_10 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 512.0
SRD2_k127_7522444_11 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 497.0
SRD2_k127_7522444_12 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 484.0
SRD2_k127_7522444_13 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 443.0
SRD2_k127_7522444_14 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 424.0
SRD2_k127_7522444_15 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 353.0
SRD2_k127_7522444_16 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 327.0
SRD2_k127_7522444_17 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 301.0
SRD2_k127_7522444_18 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 299.0
SRD2_k127_7522444_19 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005699 269.0
SRD2_k127_7522444_2 Cation transporter/ATPase, N-terminus K01531,K01535 - 3.6.3.2,3.6.3.6 6.76e-288 908.0
SRD2_k127_7522444_20 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000000000000007682 199.0
SRD2_k127_7522444_21 - - - - 0.00000000000000000000000000000000000000000000000004602 185.0
SRD2_k127_7522444_22 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000003759 184.0
SRD2_k127_7522444_24 nucleoside K03317 - - 0.00000221 49.0
SRD2_k127_7522444_25 PilZ domain - - - 0.00001082 53.0
SRD2_k127_7522444_26 Protein of unknown function (DUF3617) - - - 0.0000796 53.0
SRD2_k127_7522444_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 3.222e-211 670.0
SRD2_k127_7522444_4 TonB-dependent receptor plug - - - 1.916e-207 673.0
SRD2_k127_7522444_5 Beta-lactamase - - - 9.547e-206 670.0
SRD2_k127_7522444_6 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 8.664e-204 645.0
SRD2_k127_7522444_7 Thymidine phosphorylase K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 578.0
SRD2_k127_7522444_8 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 567.0
SRD2_k127_7522444_9 Alkaline phosphatase with broad substrate specificity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 539.0
SRD2_k127_7528012_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.95e-262 831.0
SRD2_k127_7528012_1 Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 454.0
SRD2_k127_7528012_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 281.0
SRD2_k127_7528012_3 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000002635 187.0
SRD2_k127_7528012_4 OmpA family - - - 0.000000000000000000000000000000000000000005502 161.0
SRD2_k127_7528012_5 TIR domain - - - 0.0000000000000000000000000002536 131.0
SRD2_k127_7528012_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000001834 112.0
SRD2_k127_7556173_0 Subtilase family - - - 2.334e-252 799.0
SRD2_k127_7556173_1 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 570.0
SRD2_k127_7556173_10 FeS assembly SUF system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002137 237.0
SRD2_k127_7556173_11 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000000164 202.0
SRD2_k127_7556173_12 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000116 134.0
SRD2_k127_7556173_13 Redoxin - - - 0.00000000000000000000000000000000781 134.0
SRD2_k127_7556173_14 integral membrane protein K02221 - - 0.00000000000000000000000001442 111.0
SRD2_k127_7556173_15 - - - - 0.00000000000000000005268 93.0
SRD2_k127_7556173_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 447.0
SRD2_k127_7556173_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 426.0
SRD2_k127_7556173_4 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 407.0
SRD2_k127_7556173_5 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 368.0
SRD2_k127_7556173_6 Hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 329.0
SRD2_k127_7556173_7 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 316.0
SRD2_k127_7556173_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 309.0
SRD2_k127_7556173_9 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000004874 253.0
SRD2_k127_7572348_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1036.0
SRD2_k127_7572348_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 380.0
SRD2_k127_7572348_2 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000005169 130.0
SRD2_k127_7572705_0 helicase K17675 - 3.6.4.13 0.0 1194.0
SRD2_k127_7572705_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 5.394e-303 943.0
SRD2_k127_7572705_2 Sulfotransferase family - - - 1.496e-199 632.0
SRD2_k127_7572705_3 sulfate adenylyltransferase K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 507.0
SRD2_k127_7572705_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005806 282.0
SRD2_k127_7572705_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000000001738 221.0
SRD2_k127_7572705_6 MltA-interacting protein MipA - - - 0.0000000000000000000000000000000000000000000000000000003323 204.0
SRD2_k127_7572705_7 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.000000000000000000000000000005284 124.0
SRD2_k127_7572705_8 Glycosyltransferase like family 2 - - - 0.0000000000824 64.0
SRD2_k127_7573391_0 FAD linked - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 607.0
SRD2_k127_7573391_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 344.0
SRD2_k127_7573391_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 338.0
SRD2_k127_7573391_3 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000004313 224.0
SRD2_k127_7573391_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000002477 172.0
SRD2_k127_7573391_5 Transcriptional regulator - - - 0.00000000000000008774 87.0
SRD2_k127_7615616_0 asparagine synthase K01953 - 6.3.5.4 2.89e-236 747.0
SRD2_k127_7615616_1 COG0477 Permeases of the major facilitator superfamily K16211 - - 1.637e-230 722.0
SRD2_k127_7615616_2 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 347.0
SRD2_k127_7615616_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000004729 163.0
SRD2_k127_7615616_4 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.00000000000000000000000000000000000007786 156.0
SRD2_k127_7615616_5 Transmembrane secretion effector - - - 0.0000000000005176 70.0
SRD2_k127_7615616_6 Integrase, catalytic region - - - 0.000000007226 61.0
SRD2_k127_7615616_7 - - - - 0.000001297 52.0
SRD2_k127_7665186_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 549.0
SRD2_k127_7665186_1 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 427.0
SRD2_k127_7665186_2 Nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 322.0
SRD2_k127_7665186_3 Putative ParB-like nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002522 263.0
SRD2_k127_7665186_4 Pas domain - - - 0.0000000000000000000000000000000000000000004582 162.0
SRD2_k127_7665186_5 TIR domain - - - 0.0000000000000000000000000000000000000004592 169.0
SRD2_k127_7665186_6 - - - - 0.0000000000000000000000000000001436 128.0
SRD2_k127_7665186_7 Transcriptional regulator - - - 0.000000000000000000000007892 108.0
SRD2_k127_7665186_8 Transcriptional regulator - - - 0.00000000000001346 80.0
SRD2_k127_7665186_9 Transcriptional regulator - - - 0.00007279 50.0
SRD2_k127_7683746_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1019.0
SRD2_k127_7683746_1 Erythromycin esterase - - - 2.771e-215 677.0
SRD2_k127_7683746_10 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000001306 132.0
SRD2_k127_7683746_11 Protein required for attachment to host cells - - - 0.0000000000000000000000000000002126 129.0
SRD2_k127_7683746_12 FecR protein - - - 0.000000000000000000000005684 105.0
SRD2_k127_7683746_13 Low affinity iron permease - - - 0.000000000000000000003367 99.0
SRD2_k127_7683746_14 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000001472 102.0
SRD2_k127_7683746_15 cheY-homologous receiver domain - - - 0.0000000008855 65.0
SRD2_k127_7683746_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 610.0
SRD2_k127_7683746_3 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 567.0
SRD2_k127_7683746_4 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 466.0
SRD2_k127_7683746_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 345.0
SRD2_k127_7683746_6 ABC transporter K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 327.0
SRD2_k127_7683746_7 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 299.0
SRD2_k127_7683746_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006552 265.0
SRD2_k127_7683746_9 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006712 232.0
SRD2_k127_7750193_0 ABC transporter - - - 9.441e-312 960.0
SRD2_k127_7750193_1 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 5.22e-271 853.0
SRD2_k127_7750193_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002374 278.0
SRD2_k127_7750193_11 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000001575 235.0
SRD2_k127_7750193_12 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001428 209.0
SRD2_k127_7750193_13 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000000000000000000001821 204.0
SRD2_k127_7750193_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000002394 151.0
SRD2_k127_7750193_15 Polyketide cyclase / dehydrase and lipid transport K18588 - - 0.00000000000000000000000000000000000003175 157.0
SRD2_k127_7750193_16 - - - - 0.00000000000000000006274 96.0
SRD2_k127_7750193_17 Domain of unknown function (DUF1905) - - - 0.00000000000000001191 85.0
SRD2_k127_7750193_18 MazG family K04765 - 3.6.1.9 0.00000000001937 64.0
SRD2_k127_7750193_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K20034 - 6.2.1.44 6.131e-234 734.0
SRD2_k127_7750193_3 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 9.386e-232 723.0
SRD2_k127_7750193_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 2.149e-216 685.0
SRD2_k127_7750193_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 567.0
SRD2_k127_7750193_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 544.0
SRD2_k127_7750193_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 522.0
SRD2_k127_7750193_8 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 448.0
SRD2_k127_7750193_9 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 346.0
SRD2_k127_778676_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1144.0
SRD2_k127_778676_1 Transferrin receptor-like dimerisation domain - - - 6.518e-213 671.0
SRD2_k127_778676_2 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 530.0
SRD2_k127_778676_3 PA domain K01269 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 341.0
SRD2_k127_778676_4 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004791 283.0
SRD2_k127_7888506_0 YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 504.0
SRD2_k127_7888506_1 YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 420.0
SRD2_k127_7888506_2 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000006627 206.0
SRD2_k127_790284_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.372e-248 771.0
SRD2_k127_790284_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 8.576e-247 766.0
SRD2_k127_790284_10 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000347 241.0
SRD2_k127_790284_11 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000004446 174.0
SRD2_k127_790284_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000005378 176.0
SRD2_k127_790284_14 DNA mediated transformation - - - 0.0000000000000000000000000000000000002288 151.0
SRD2_k127_790284_15 ThiS family - - - 0.0000000000000000000552 100.0
SRD2_k127_790284_16 - - - - 0.000000000002635 73.0
SRD2_k127_790284_17 YCII-related domain K09780 - - 0.000009283 51.0
SRD2_k127_790284_18 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001424 52.0
SRD2_k127_790284_2 Sugar (and other) transporter - - - 2.05e-196 622.0
SRD2_k127_790284_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 554.0
SRD2_k127_790284_4 beta-glucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 513.0
SRD2_k127_790284_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 454.0
SRD2_k127_790284_6 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 394.0
SRD2_k127_790284_7 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002775 250.0
SRD2_k127_790284_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000002859 239.0
SRD2_k127_790284_9 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002957 240.0
SRD2_k127_792725_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.29e-219 691.0
SRD2_k127_792725_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 600.0
SRD2_k127_792725_10 Domain of unknown function (DUF1476) - - - 0.000000000000000000000000000000000007468 146.0
SRD2_k127_792725_11 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000002944 120.0
SRD2_k127_792725_12 PFAM VanZ - - - 0.000000000000000000000000008859 114.0
SRD2_k127_792725_13 - - - - 0.0000000000000000000000006271 117.0
SRD2_k127_792725_14 PAS domain - - - 0.0000000000000000000001177 113.0
SRD2_k127_792725_15 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000001504 68.0
SRD2_k127_792725_16 Pilus assembly protein PilZ - - - 0.0000007266 57.0
SRD2_k127_792725_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 496.0
SRD2_k127_792725_3 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 412.0
SRD2_k127_792725_4 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 392.0
SRD2_k127_792725_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 362.0
SRD2_k127_792725_6 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000582 193.0
SRD2_k127_792725_7 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000001172 177.0
SRD2_k127_792725_8 Protein of unknown function (DUF4230) - - - 0.000000000000000000000000000000000000000000000004889 185.0
SRD2_k127_792725_9 PFAM Sterol-binding domain protein - - - 0.0000000000000000000000000000000000002425 142.0
SRD2_k127_7954297_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 4.495e-241 758.0
SRD2_k127_7954297_1 Erythromycin esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 524.0
SRD2_k127_7954297_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 438.0
SRD2_k127_7954297_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001643 252.0
SRD2_k127_7954297_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000004127 174.0
SRD2_k127_7954297_5 ThiS family - - - 0.000000000000000000000027 101.0