logo

Overview

ID MAG03890
Name TH1_bin.8
Sample SMP0100
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Methylococcales
Family Methylomonadaceae
Genus
Species
Assembly information
Completeness (%) 92.18
Contamination (%) 2.46
GC content (%) 53.0
N50 (bp) 6,243
Genome size (bp) 2,408,020

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2488

Gene name Description KEGG GOs EC E-value Score Sequence
TH1_k127_1003837_0 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 471.0
TH1_k127_1003837_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 436.0
TH1_k127_1003837_10 Protein of unknown function (DUF1640) - - - 0.000000000000000000000000000007004 124.0
TH1_k127_1003837_11 Phosphopantetheine attachment site - - - 0.0000000000000000000000000006725 114.0
TH1_k127_1003837_12 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000002431 113.0
TH1_k127_1003837_13 ErfK ybiS ycfS ynhG family protein - - - 0.00000000002167 68.0
TH1_k127_1003837_14 PFAM Uncharacterised protein family UPF0150 - - - 0.000000109 57.0
TH1_k127_1003837_2 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 357.0
TH1_k127_1003837_3 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
TH1_k127_1003837_4 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 323.0
TH1_k127_1003837_5 TIGRFAM TIGR00266 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 302.0
TH1_k127_1003837_6 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002982 267.0
TH1_k127_1003837_7 TIGRFAM Addiction module toxin, Txe YoeB K19158 - - 0.0000000000000000000000000000000000000000004363 158.0
TH1_k127_1003837_8 Antitoxin component of a toxin-antitoxin (TA) module K19159 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015643,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042710,GO:0043565,GO:0044010,GO:0044764,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051704,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000004745 140.0
TH1_k127_1003837_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000014 143.0
TH1_k127_1018028_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1075.0
TH1_k127_1018028_1 Zinc-ribbon containing domain - - - 0.00000000000000000000000000002788 121.0
TH1_k127_1026596_0 Radical SAM superfamily K04069 - 1.97.1.4 2.801e-199 625.0
TH1_k127_1026596_1 Efflux pump membrane transporter K18138 - - 0.000000000000000000001602 96.0
TH1_k127_1026596_2 Belongs to the MEMO1 family K06990 - - 0.000000000000000003367 87.0
TH1_k127_1098908_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 602.0
TH1_k127_1098908_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 463.0
TH1_k127_1098908_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000002566 125.0
TH1_k127_1102455_0 Pfam Transposase IS66 - - - 1.707e-216 681.0
TH1_k127_1102455_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 440.0
TH1_k127_1102455_2 FMN_bind - - - 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
TH1_k127_1102455_3 - - - - 0.00000000000000000022 89.0
TH1_k127_1102904_0 Belongs to the alpha-IPM synthase homocitrate synthase family K09011 - 2.3.1.182 3.13e-291 900.0
TH1_k127_1102904_1 DEAD DEAH box K03724 - - 0.000000000000000001644 86.0
TH1_k127_11080_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.187e-213 675.0
TH1_k127_11080_1 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 334.0
TH1_k127_11080_2 zinc ion binding K06204 - - 0.00000000000000000000000000000001628 126.0
TH1_k127_111510_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.128e-237 736.0
TH1_k127_111510_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 569.0
TH1_k127_111510_10 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 400.0
TH1_k127_111510_11 3-oxoacyl-(Acyl-carrier-protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 394.0
TH1_k127_111510_12 PFAM Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 393.0
TH1_k127_111510_13 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 332.0
TH1_k127_111510_14 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 325.0
TH1_k127_111510_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004874 277.0
TH1_k127_111510_16 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000000000000005528 228.0
TH1_k127_111510_17 PFAM Type IV pilus assembly PilZ K02676 - - 0.0000000000000000000000000000000000000000000000000000008006 196.0
TH1_k127_111510_18 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000003561 197.0
TH1_k127_111510_19 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000007847 170.0
TH1_k127_111510_2 PFAM Binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 539.0
TH1_k127_111510_20 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000002963 140.0
TH1_k127_111510_21 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000007517 134.0
TH1_k127_111510_22 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000009411 98.0
TH1_k127_111510_23 - - - - 0.00000000000007684 73.0
TH1_k127_111510_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 505.0
TH1_k127_111510_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 500.0
TH1_k127_111510_5 PFAM Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 496.0
TH1_k127_111510_6 Multicopper oxidase K04753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 490.0
TH1_k127_111510_7 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 464.0
TH1_k127_111510_8 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 462.0
TH1_k127_111510_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 417.0
TH1_k127_1173900_0 tRNA (guanine-N7-)-methyltransferase activity - - - 0.0 1047.0
TH1_k127_1173900_1 PFAM Aminotransferase, class I K00812,K02028,K12252 - 2.6.1.1,2.6.1.84,3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 564.0
TH1_k127_1173900_10 Nacht domain - - - 0.0000001332 55.0
TH1_k127_1173900_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 445.0
TH1_k127_1173900_3 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 299.0
TH1_k127_1173900_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000001137 259.0
TH1_k127_1173900_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000001634 243.0
TH1_k127_1173900_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000003534 220.0
TH1_k127_1173900_7 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000003956 181.0
TH1_k127_1173900_8 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000000000000000003793 164.0
TH1_k127_1173900_9 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000000000001621 146.0
TH1_k127_1184953_0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000008042 257.0
TH1_k127_1184953_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004474 232.0
TH1_k127_1184953_2 Belongs to the 'phage' integrase family K04763 - - 0.000000008217 56.0
TH1_k127_1208521_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 289.0
TH1_k127_1208521_1 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007336 263.0
TH1_k127_1208521_2 TIGRFAM histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000001809 187.0
TH1_k127_1208521_3 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000004378 175.0
TH1_k127_1208521_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000008671 158.0
TH1_k127_121540_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.801e-228 714.0
TH1_k127_121540_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 315.0
TH1_k127_121540_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000664 128.0
TH1_k127_121771_0 TIGRFAM RNA polymerase sigma factor RpoS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 462.0
TH1_k127_121771_1 MoeA N-terminal region (domain I K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 391.0
TH1_k127_121771_2 molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000000000000000000000000000000000000000000008953 220.0
TH1_k127_121771_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000001662 133.0
TH1_k127_121771_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000005995 124.0
TH1_k127_121771_5 Peptidase, M23 family K06194 - - 0.00000000004805 64.0
TH1_k127_121771_6 Lysin motif K06194 - - 0.00002798 48.0
TH1_k127_1233670_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 567.0
TH1_k127_1233670_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 524.0
TH1_k127_1233670_2 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 491.0
TH1_k127_1233670_3 PFAM Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 354.0
TH1_k127_1246126_0 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 486.0
TH1_k127_1246126_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 415.0
TH1_k127_1246126_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 416.0
TH1_k127_1246126_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 360.0
TH1_k127_1246126_4 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000006408 228.0
TH1_k127_1246126_5 STAS domain K07122 - - 0.000000000000000000000005449 105.0
TH1_k127_1246126_6 Cation transporter/ATPase, N-terminus - - - 0.000000001593 59.0
TH1_k127_1246499_0 RNA helicase K11927 - 3.6.4.13 7.052e-202 636.0
TH1_k127_1246499_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 346.0
TH1_k127_1246499_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 321.0
TH1_k127_1246499_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 297.0
TH1_k127_1246499_4 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000002502 233.0
TH1_k127_1246499_5 - - - - 0.00000000000000000006927 93.0
TH1_k127_12585_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1550.0
TH1_k127_12585_1 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 440.0
TH1_k127_12585_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 402.0
TH1_k127_12585_3 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 298.0
TH1_k127_12585_4 - - - - 0.0000000000000000000000000000000000009554 142.0
TH1_k127_12585_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000102 136.0
TH1_k127_12585_6 Outer membrane efflux protein - - - 0.000000000001779 67.0
TH1_k127_1270919_0 Coenzyme A transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 456.0
TH1_k127_1270919_1 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 306.0
TH1_k127_1270919_2 PFAM short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005442 262.0
TH1_k127_1270919_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K22364 - 1.8.1.5 0.0000000000000000007393 86.0
TH1_k127_1287122_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 550.0
TH1_k127_1287122_1 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 512.0
TH1_k127_1287122_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 438.0
TH1_k127_1287122_3 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 379.0
TH1_k127_1287122_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 306.0
TH1_k127_1287122_5 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 305.0
TH1_k127_1287122_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 286.0
TH1_k127_1287122_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000001158 233.0
TH1_k127_1287122_8 Circularly permuted ATP-grasp type 2 - - - 0.0000000000000000000001932 96.0
TH1_k127_1294896_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 3.393e-275 869.0
TH1_k127_1294896_1 Belongs to the RtcB family K14415 - 6.5.1.3 3.539e-243 757.0
TH1_k127_1294896_10 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000000000000008401 203.0
TH1_k127_1294896_11 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000000000002015 173.0
TH1_k127_1294896_12 - - - - 0.000000000000000000000000000000000000000000001974 171.0
TH1_k127_1294896_13 Ferredoxin - - - 0.000000000000000000000000000000000000000000008018 165.0
TH1_k127_1294896_14 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000001123 146.0
TH1_k127_1294896_15 HicB family - - - 0.0000000000000000000000000000003524 123.0
TH1_k127_1294896_16 Protein of unknown function (DUF1640) - - - 0.0000000000000000009543 91.0
TH1_k127_1294896_17 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 0.000000000000000002783 86.0
TH1_k127_1294896_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000408 59.0
TH1_k127_1294896_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 5.07e-224 701.0
TH1_k127_1294896_3 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 608.0
TH1_k127_1294896_4 virion core protein (lumpy skin disease virus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 462.0
TH1_k127_1294896_5 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 394.0
TH1_k127_1294896_6 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 347.0
TH1_k127_1294896_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 313.0
TH1_k127_1294896_8 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
TH1_k127_1294896_9 toxin-antitoxin system toxin component, PIN family - - - 0.0000000000000000000000000000000000000000000000000000000000000102 218.0
TH1_k127_1336675_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 482.0
TH1_k127_1336675_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 297.0
TH1_k127_1336675_2 Plant specific mitochondrial import receptor subunit TOM20 - - - 0.0000000002906 65.0
TH1_k127_1391557_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.277e-241 754.0
TH1_k127_1391557_1 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 608.0
TH1_k127_1391557_2 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 412.0
TH1_k127_1391557_3 PFAM YkuD domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 356.0
TH1_k127_1391557_4 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 308.0
TH1_k127_1391557_5 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 263.0
TH1_k127_1391557_6 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000232 189.0
TH1_k127_1391557_7 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000008046 107.0
TH1_k127_1391557_8 PFAM BFD-like 2Fe-2S -binding K02192 - - 0.000000000000000001995 86.0
TH1_k127_1404675_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 2.126e-216 674.0
TH1_k127_1404675_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 575.0
TH1_k127_1420296_0 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 594.0
TH1_k127_1420296_1 Cellulose biosynthesis protein BcsQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 291.0
TH1_k127_1420296_2 - - - - 0.000000000000000000000000000000000000004859 152.0
TH1_k127_1420296_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.000000000000000000000000004543 114.0
TH1_k127_1420296_4 6-phosphogluconolactonase K01057 - 3.1.1.31 0.000601 43.0
TH1_k127_1422866_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 2.767e-212 664.0
TH1_k127_1422866_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 412.0
TH1_k127_1422866_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 410.0
TH1_k127_1422866_3 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 407.0
TH1_k127_1422866_4 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006916 281.0
TH1_k127_1422866_5 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007149 266.0
TH1_k127_1422866_6 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000009719 157.0
TH1_k127_1422866_7 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000005506 123.0
TH1_k127_1422866_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000005155 66.0
TH1_k127_143199_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 2.673e-287 885.0
TH1_k127_143199_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.147e-226 702.0
TH1_k127_143199_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 398.0
TH1_k127_143199_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 324.0
TH1_k127_143199_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000898 271.0
TH1_k127_143199_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007608 252.0
TH1_k127_143199_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000007343 171.0
TH1_k127_143199_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000001889 149.0
TH1_k127_143199_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000131 133.0
TH1_k127_143199_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000009685 50.0
TH1_k127_143464_0 Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 381.0
TH1_k127_143464_1 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 295.0
TH1_k127_143464_2 Cytochrome c oxidase, subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 281.0
TH1_k127_143464_3 - - - - 0.000000000000000000000000000000000002963 140.0
TH1_k127_143464_4 methyltransferase activity - - - 0.0000000000000000000000000000007746 127.0
TH1_k127_143464_5 - - - - 0.000000000000000002258 85.0
TH1_k127_143464_6 - - - - 0.00000000001467 69.0
TH1_k127_143464_7 - - - - 0.00000419 49.0
TH1_k127_143464_8 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00006381 46.0
TH1_k127_1440500_0 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 496.0
TH1_k127_1440500_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 485.0
TH1_k127_1440500_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000017 84.0
TH1_k127_1444728_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 565.0
TH1_k127_145300_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 1.593e-235 739.0
TH1_k127_145300_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 319.0
TH1_k127_145300_2 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007314 252.0
TH1_k127_145300_3 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000001253 232.0
TH1_k127_1469157_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 7.216e-266 824.0
TH1_k127_1469157_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 356.0
TH1_k127_1469157_2 Protein of unknown function (DUF3240) - - - 0.00000000000000000000000000000000000000169 149.0
TH1_k127_1469157_3 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000009214 119.0
TH1_k127_1469157_4 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000006725 114.0
TH1_k127_1469157_5 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000756 108.0
TH1_k127_147466_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 473.0
TH1_k127_147466_1 molybdenum ABC transporter, periplasmic K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 349.0
TH1_k127_147466_2 ABC transporter permease protein K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 319.0
TH1_k127_147466_3 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000005154 164.0
TH1_k127_147466_4 Alginate export - - - 0.000000000000000002234 85.0
TH1_k127_147466_5 Alginate export - - - 0.0002378 45.0
TH1_k127_1479844_0 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 378.0
TH1_k127_1479844_1 LemA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 342.0
TH1_k127_1479844_2 membrane - - - 0.000000000000000000000000000000000000000000000000000001284 198.0
TH1_k127_1487472_0 Glycosyl hydrolases family 17 - - - 1.003e-208 667.0
TH1_k127_1487472_1 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 411.0
TH1_k127_1487472_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000195 185.0
TH1_k127_1487472_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000001351 112.0
TH1_k127_1487472_4 HupE / UreJ protein K03192 - - 0.00001036 48.0
TH1_k127_1497439_0 PFAM Major Facilitator Superfamily K02575 - - 0.0 1495.0
TH1_k127_1497439_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004913 241.0
TH1_k127_1497439_2 Transcriptional regulator K13771 - - 0.00000000000000000000000000000000000000000000000000000001731 201.0
TH1_k127_1497439_3 Alkaline phosphatase - - - 0.00000000000000000000000000000000000000000000000000003107 202.0
TH1_k127_1497439_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.000000000000000000000000000000001398 129.0
TH1_k127_1510868_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1299.0
TH1_k127_1510868_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 2.163e-234 730.0
TH1_k127_1510868_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 1.24e-203 640.0
TH1_k127_1510868_3 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 5.715e-200 633.0
TH1_k127_1510868_4 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 570.0
TH1_k127_1510868_5 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 287.0
TH1_k127_1510868_6 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000000006698 161.0
TH1_k127_1510868_7 Domain of unknown function (DUF4442) - - - 0.0000000000000004994 79.0
TH1_k127_1515978_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.367e-247 771.0
TH1_k127_1515978_1 Penicillin-Binding Protein C-terminus Family - - - 1.587e-224 717.0
TH1_k127_1515978_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000002028 141.0
TH1_k127_1517021_0 Belongs to the transketolase family - - - 0.0 1119.0
TH1_k127_1517021_1 PFAM Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 298.0
TH1_k127_1517021_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000002878 178.0
TH1_k127_15211_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 439.0
TH1_k127_15211_1 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 306.0
TH1_k127_15211_2 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000002594 179.0
TH1_k127_15211_3 - - - - 0.000000000000000000000000000000006486 138.0
TH1_k127_1523203_0 Ammonium Transporter K03320 - - 4.307e-245 762.0
TH1_k127_1523203_1 PFAM Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 322.0
TH1_k127_1523203_2 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000003842 207.0
TH1_k127_1525666_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 6.204e-197 619.0
TH1_k127_1525666_1 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000000000000000000000000000000000000000104 229.0
TH1_k127_1525666_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000002147 229.0
TH1_k127_1525666_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000004025 217.0
TH1_k127_1525666_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000001565 168.0
TH1_k127_1545057_0 type II III secretion system K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 510.0
TH1_k127_1545057_1 general secretion pathway protein - - - 0.00000000000000289 85.0
TH1_k127_1545057_2 Peptidase family M3 K01414 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006465,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0034645,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051604,GO:0070011,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901576 3.4.24.70 0.0000000000001704 74.0
TH1_k127_1545057_3 PFAM General secretion pathway protein M K02462 - - 0.00000008907 55.0
TH1_k127_155169_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1358.0
TH1_k127_155169_1 Helix-hairpin-helix containing domain - - - 0.0 1255.0
TH1_k127_155169_2 transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
TH1_k127_155169_3 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009599 258.0
TH1_k127_155169_4 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000001401 211.0
TH1_k127_155169_5 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000003594 209.0
TH1_k127_155169_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000002923 191.0
TH1_k127_1566551_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.914e-308 948.0
TH1_k127_1566551_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000001202 238.0
TH1_k127_1566551_2 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000006914 190.0
TH1_k127_1566551_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000001638 184.0
TH1_k127_1566551_4 - - - - 0.0000000000000009852 78.0
TH1_k127_157975_0 PFAM Uncharacterised protein family (UPF0182) K09118 - - 0.0 1126.0
TH1_k127_157975_1 PFAM Binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 601.0
TH1_k127_157975_2 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004371 248.0
TH1_k127_157975_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000003091 181.0
TH1_k127_157975_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000004995 175.0
TH1_k127_157975_6 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000009129 55.0
TH1_k127_1580138_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 573.0
TH1_k127_1580138_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 377.0
TH1_k127_1580138_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 313.0
TH1_k127_1585696_0 SCO1/SenC - - - 2.342e-277 865.0
TH1_k127_1585696_1 56kDa selenium binding protein (SBP56) K17285 - - 2.465e-243 757.0
TH1_k127_1585696_2 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002484 273.0
TH1_k127_1585696_3 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005883 263.0
TH1_k127_1585696_4 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000000001368 157.0
TH1_k127_1585696_5 - - - - 0.00000000000000000000000000000004195 129.0
TH1_k127_1585696_6 TrkA-C domain K03499 - - 0.0000000000000000000000000001346 115.0
TH1_k127_1596256_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1420.0
TH1_k127_1596256_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1407.0
TH1_k127_1596256_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.57e-238 744.0
TH1_k127_1596256_3 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 533.0
TH1_k127_1596256_4 transcriptional regulator, Crp K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 319.0
TH1_k127_1596256_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000004402 224.0
TH1_k127_161292_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 311.0
TH1_k127_161292_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 302.0
TH1_k127_161292_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000007562 263.0
TH1_k127_1648633_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 2.34e-204 643.0
TH1_k127_1648633_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 411.0
TH1_k127_1648633_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 346.0
TH1_k127_166946_0 DNA RNA helicase - - - 0.0 1042.0
TH1_k127_166946_1 FAD linked oxidases, C-terminal domain K03777 - 1.1.5.12 1.222e-220 694.0
TH1_k127_166946_10 Periplasmic or secreted lipoprotein - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000006011 115.0
TH1_k127_166946_2 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 548.0
TH1_k127_166946_3 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 445.0
TH1_k127_166946_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
TH1_k127_166946_5 isomerase K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 320.0
TH1_k127_166946_6 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000005732 230.0
TH1_k127_166946_7 serine threonine protein kinase K08884,K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000002209 239.0
TH1_k127_166946_8 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000001042 155.0
TH1_k127_166946_9 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000004173 132.0
TH1_k127_1674091_0 Aldehyde dehydrogenase family - - - 8.428e-217 681.0
TH1_k127_1674091_1 ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 559.0
TH1_k127_1674091_2 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002369 287.0
TH1_k127_1674091_3 Glycosyl transferase family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005452 269.0
TH1_k127_1674091_4 Cobalamin-independent synthase, Catalytic domain - - - 0.0000000000000000000000000000000000000000000004795 167.0
TH1_k127_1674091_5 - - - - 0.0000000000000000000000006451 109.0
TH1_k127_1674091_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000003781 49.0
TH1_k127_1674762_0 Aconitase C-terminal domain - - - 0.0 1194.0
TH1_k127_1674762_1 Cytochrome c oxidase subunit K02298 - 1.10.3.10 0.0 1157.0
TH1_k127_1674762_2 Cytochrome C oxidase subunit II, periplasmic domain K02297 - 1.10.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 390.0
TH1_k127_1674762_3 oxidase subunit K02299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 304.0
TH1_k127_1674762_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000006332 141.0
TH1_k127_1674762_5 oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor K02300 - - 0.00000000000000000000000000000235 124.0
TH1_k127_1674762_6 - - - - 0.0000001256 55.0
TH1_k127_1691535_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 6.239e-219 687.0
TH1_k127_1691535_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 602.0
TH1_k127_1691535_2 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000000000000000000000001967 162.0
TH1_k127_1691535_3 Alginate export - - - 0.000000000000000001351 86.0
TH1_k127_1699340_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 2.139e-223 698.0
TH1_k127_1699340_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 524.0
TH1_k127_1723013_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0 1146.0
TH1_k127_1723013_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 1.307e-222 701.0
TH1_k127_1723013_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 597.0
TH1_k127_1723013_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 559.0
TH1_k127_1723013_4 TIGRFAM Lipopolysaccharide heptosyltransferase II K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 475.0
TH1_k127_1723013_5 TIGRFAM lipopolysaccharide heptosyltransferase I K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 446.0
TH1_k127_1723013_6 Oxygen tolerance - - - 0.0000000000000000000000000000000000001379 149.0
TH1_k127_1723013_7 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00001774 47.0
TH1_k127_173643_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 2.605e-249 771.0
TH1_k127_173643_1 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 561.0
TH1_k127_173643_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000002513 243.0
TH1_k127_173643_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000242 226.0
TH1_k127_173643_4 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000000000000000000000001768 183.0
TH1_k127_173643_5 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000009554 127.0
TH1_k127_173643_6 Protein of unknown function (DUF2818) - - - 0.00000000000000000000000005451 115.0
TH1_k127_173802_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 571.0
TH1_k127_173802_1 - - - - 0.00000001583 59.0
TH1_k127_1740266_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009728 588.0
TH1_k127_1740266_1 TIGRFAM type I secretion outer membrane protein, TolC K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 479.0
TH1_k127_1740266_2 deoxycytidine triphosphate deaminase K09948 - - 0.00000000000000000000000000000000000005539 146.0
TH1_k127_1745655_0 HI0933-like protein K10210 - 1.14.99.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 507.0
TH1_k127_1745655_1 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000006209 208.0
TH1_k127_1745655_2 - - - - 0.000000000000000000000000000000000000002213 151.0
TH1_k127_1745655_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000003888 119.0
TH1_k127_1795614_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 447.0
TH1_k127_1795614_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 410.0
TH1_k127_1795614_2 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002064 282.0
TH1_k127_1795614_3 Cytochrome C' - - - 0.00000000000000000000000000000000000000000000000000000002194 203.0
TH1_k127_1795614_4 transaminase activity K00375,K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000001405 207.0
TH1_k127_1795614_6 InterPro IPR001584 COGs COG2801 - - - 0.00001324 51.0
TH1_k127_1812284_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 2.666e-290 895.0
TH1_k127_1812284_1 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 363.0
TH1_k127_1812284_2 exporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 284.0
TH1_k127_1812284_3 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000000005792 172.0
TH1_k127_1812284_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000002064 109.0
TH1_k127_183052_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K01507,K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 561.0
TH1_k127_183052_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001073 271.0
TH1_k127_1840981_0 TIGRFAM Nitrate transport ATP-binding K15578 - - 0.0 999.0
TH1_k127_1840981_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 7.854e-237 738.0
TH1_k127_1840981_2 PFAM Binding-protein-dependent transport systems inner membrane component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 564.0
TH1_k127_1840981_3 membrane protein of uknown function UCP014873 - - - 0.0000002623 60.0
TH1_k127_1840981_4 Alginate export - - - 0.000005261 52.0
TH1_k127_189464_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 1.485e-248 785.0
TH1_k127_189464_1 TIGRFAM type I secretion membrane fusion protein, HlyD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004117 248.0
TH1_k127_189464_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000001281 149.0
TH1_k127_1953289_0 Iron-containing alcohol dehydrogenase - - - 2.96e-221 689.0
TH1_k127_1953289_1 Uncharacterized protein conserved in bacteria N-term (DUF3322) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 597.0
TH1_k127_1953289_2 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000001129 162.0
TH1_k127_1953289_3 Putative exonuclease SbcCD, C subunit - - - 0.0000000000000000000002945 96.0
TH1_k127_2030142_0 argininosuccinate lyase K01755 - 4.3.2.1 1.867e-225 707.0
TH1_k127_2030142_1 Aminotransferase, class I K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 602.0
TH1_k127_2030142_10 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000947 272.0
TH1_k127_2030142_11 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002349 274.0
TH1_k127_2030142_12 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007113 261.0
TH1_k127_2030142_13 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000002224 230.0
TH1_k127_2030142_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000000000000005257 219.0
TH1_k127_2030142_15 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ - - - 0.00000000000000000000000000000000000000000000007078 173.0
TH1_k127_2030142_16 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000002987 106.0
TH1_k127_2030142_17 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000004347 92.0
TH1_k127_2030142_18 Selenoprotein, putative - - - 0.00000000000002414 75.0
TH1_k127_2030142_2 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 584.0
TH1_k127_2030142_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 520.0
TH1_k127_2030142_4 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 521.0
TH1_k127_2030142_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 449.0
TH1_k127_2030142_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 445.0
TH1_k127_2030142_7 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 424.0
TH1_k127_2030142_8 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 376.0
TH1_k127_2030142_9 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 351.0
TH1_k127_2067714_0 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 547.0
TH1_k127_2067714_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 404.0
TH1_k127_2087803_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 479.0
TH1_k127_2087803_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 370.0
TH1_k127_2087803_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 342.0
TH1_k127_2087803_3 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001869 274.0
TH1_k127_2087803_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000008374 145.0
TH1_k127_2087803_5 - - - - 0.0000004941 56.0
TH1_k127_2099877_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 353.0
TH1_k127_2099877_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 341.0
TH1_k127_2099877_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004064 276.0
TH1_k127_2099877_3 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00001763 53.0
TH1_k127_2159466_0 Alginate export - - - 9.907e-252 783.0
TH1_k127_2159466_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 5.01e-221 698.0
TH1_k127_2159466_10 domain protein - - - 0.00000000000000002147 84.0
TH1_k127_2159466_11 PFAM Integrase core domain - - - 0.00000000002077 66.0
TH1_k127_2159466_12 Small protein - - - 0.0000001749 55.0
TH1_k127_2159466_13 Protein of unknown function (DUF1698) - - - 0.000004968 59.0
TH1_k127_2159466_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 567.0
TH1_k127_2159466_3 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 561.0
TH1_k127_2159466_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 497.0
TH1_k127_2159466_5 PFAM Bacterial extracellular solute-binding K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 496.0
TH1_k127_2159466_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 455.0
TH1_k127_2159466_7 Bacterial regulatory helix-turn-helix protein, lysR family K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 345.0
TH1_k127_2159466_8 ABC transporter permease protein K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 284.0
TH1_k127_2159466_9 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 270.0
TH1_k127_2166331_0 Belongs to the heat shock protein 70 family - - - 3.914e-315 975.0
TH1_k127_2166331_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 384.0
TH1_k127_2166331_2 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001346 271.0
TH1_k127_2166331_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000001834 241.0
TH1_k127_2166331_4 PFAM CreA K05805 - - 0.00000000000000000000000000000006509 126.0
TH1_k127_217099_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000001808 220.0
TH1_k127_217099_1 Conserved Protein - - - 0.000000000000000000000000000000001734 134.0
TH1_k127_217099_2 - - - - 0.000000000000000000000000000000003373 144.0
TH1_k127_217099_3 META domain K09914 - - 0.00000000000000005126 87.0
TH1_k127_217099_4 - - - - 0.0002758 45.0
TH1_k127_2183570_0 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 601.0
TH1_k127_2183570_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 388.0
TH1_k127_2183570_2 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 319.0
TH1_k127_2183570_3 type IV, pilus assembly K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004361 251.0
TH1_k127_2183570_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000004309 211.0
TH1_k127_2183570_5 TIGRFAM Mutator MutT protein K03574 - 3.6.1.55 0.0000000000000000000000000000000001884 135.0
TH1_k127_2231977_0 ubiE/COQ5 methyltransferase family K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 372.0
TH1_k127_2231977_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 293.0
TH1_k127_2231977_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000007061 159.0
TH1_k127_2243431_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 7.623e-208 655.0
TH1_k127_2243431_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000007427 81.0
TH1_k127_2243431_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000001826 65.0
TH1_k127_2256561_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 608.0
TH1_k127_2256561_1 PFAM Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 552.0
TH1_k127_2256561_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000001051 228.0
TH1_k127_2256561_3 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 0.00000000000000000000000000000000000000000000000000000003629 202.0
TH1_k127_2256561_4 Protein of unknown function (DUF2934) - - - 0.000000000006074 68.0
TH1_k127_2258098_0 Arginine deiminase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 312.0
TH1_k127_2258098_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0000000000000000000000000000005655 127.0
TH1_k127_2258098_2 Transposase - - - 0.000000000000000000363 90.0
TH1_k127_2300672_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1040.0
TH1_k127_2300672_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.771e-198 629.0
TH1_k127_2300672_10 Domain of unknown function (DUF4845) - - - 0.000000000000000000000000000000001092 133.0
TH1_k127_2300672_11 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.00000000003844 70.0
TH1_k127_2300672_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 453.0
TH1_k127_2300672_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 409.0
TH1_k127_2300672_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 372.0
TH1_k127_2300672_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 301.0
TH1_k127_2300672_6 PFAM NnrS K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 300.0
TH1_k127_2300672_7 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 292.0
TH1_k127_2300672_8 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000004358 241.0
TH1_k127_2300672_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000002875 173.0
TH1_k127_2318951_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1223.0
TH1_k127_2318951_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 574.0
TH1_k127_2318951_2 fructose-bisphosphate aldolase, class II, yeast E. coli subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 464.0
TH1_k127_2318951_3 PFAM Orotidine 5'-phosphate decarboxylase K08093 - 4.1.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
TH1_k127_2318951_4 SIS domain K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 303.0
TH1_k127_2318951_5 - - - - 0.0000000000000000000000000000000000000005825 157.0
TH1_k127_2318951_6 - - - - 0.000000000006733 74.0
TH1_k127_2351735_0 COG0480 Translation elongation factors (GTPases) K02355 - - 1.359e-280 871.0
TH1_k127_2351735_1 FAD binding domain K09828 - 1.3.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 589.0
TH1_k127_2363102_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1041.0
TH1_k127_2363102_1 ABC1 family K03688 - - 2.973e-277 861.0
TH1_k127_2363102_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001173 231.0
TH1_k127_2363720_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 593.0
TH1_k127_2363720_1 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 374.0
TH1_k127_2363720_2 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 315.0
TH1_k127_2363720_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000133 171.0
TH1_k127_2363720_4 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000002503 63.0
TH1_k127_2414361_0 Mg chelatase-related protein K07391 - - 6.978e-253 787.0
TH1_k127_2414361_1 TIGRFAM Pilus retraction protein PilT K02669 - - 1.275e-198 622.0
TH1_k127_2414361_2 TIGRFAM Pilus retraction protein PilT K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 597.0
TH1_k127_2414361_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 358.0
TH1_k127_2414361_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 314.0
TH1_k127_2414361_5 Membrane fusogenic activity K09806 - - 0.0000000000000000000000000003386 116.0
TH1_k127_2429209_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 478.0
TH1_k127_2429209_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002088 273.0
TH1_k127_2429209_2 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000009027 272.0
TH1_k127_2429209_3 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000001953 242.0
TH1_k127_2429209_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000456 138.0
TH1_k127_2429209_5 - - - - 0.0000000000000000000000000000000007146 152.0
TH1_k127_2429209_6 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000002062 118.0
TH1_k127_2429209_7 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000001379 135.0
TH1_k127_2429209_8 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000669 63.0
TH1_k127_2433326_0 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 534.0
TH1_k127_2433326_1 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 481.0
TH1_k127_2433326_2 PFAM ATP-grasp fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 381.0
TH1_k127_2433326_3 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000001093 128.0
TH1_k127_2469095_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1561.0
TH1_k127_2469095_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 369.0
TH1_k127_2469095_2 Outer membrane efflux protein - - - 0.00000000001826 65.0
TH1_k127_2469095_3 Protein of unknown function (DUF3240) - - - 0.0000001901 54.0
TH1_k127_2504132_0 Cytochrome bd terminal oxidase subunit I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 506.0
TH1_k127_2504132_1 lipocalin K03098 - - 0.000000000000000000000000000000000000000000000000000000000001665 214.0
TH1_k127_2504132_2 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000008351 206.0
TH1_k127_2504132_3 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000166 74.0
TH1_k127_2504132_4 Sensors of blue-light using FAD - - - 0.00000000136 59.0
TH1_k127_2520348_0 TIGRFAM RNA helicase, ATP-dependent DEAH box, HrpA type K03578 - 3.6.4.13 2.734e-259 807.0
TH1_k127_2520348_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 520.0
TH1_k127_2520348_2 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 380.0
TH1_k127_2520348_3 PFAM HopJ type III effector protein - - - 0.00000000000000000000000000000000000000003873 156.0
TH1_k127_2520348_4 TonB C terminal K03832 - - 0.0000000000001038 77.0
TH1_k127_2528817_0 TIGRFAM SUF system FeS cluster assembly, SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 526.0
TH1_k127_2528817_1 ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 430.0
TH1_k127_2528817_2 FeS assembly protein SufB K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001973 253.0
TH1_k127_2530031_0 ABC-type uncharacterized transport system - - - 3.925e-267 835.0
TH1_k127_2530031_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 477.0
TH1_k127_2530031_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 420.0
TH1_k127_2530031_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 360.0
TH1_k127_2530031_4 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 313.0
TH1_k127_2530031_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000009676 254.0
TH1_k127_2530031_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000002154 98.0
TH1_k127_2530031_7 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000008654 65.0
TH1_k127_2530031_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000003778 56.0
TH1_k127_2530031_9 carboxylic ester hydrolase activity - - - 0.00004956 48.0
TH1_k127_2656900_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 7.14e-243 754.0
TH1_k127_2656900_1 PFAM Aminotransferase - - - 3.013e-197 619.0
TH1_k127_2656900_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 454.0
TH1_k127_2656900_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 391.0
TH1_k127_2656900_4 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000009071 101.0
TH1_k127_269074_0 Putative exonuclease SbcCD, C subunit - - - 0.0 1019.0
TH1_k127_269074_1 Domain of unknown function (DUF4194) - - - 0.0000000000000000000000000000000000000000002736 159.0
TH1_k127_2714554_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.891e-238 752.0
TH1_k127_2714554_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 496.0
TH1_k127_2714554_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 290.0
TH1_k127_2714554_3 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000006612 187.0
TH1_k127_2752224_0 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 555.0
TH1_k127_2752224_1 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000008832 166.0
TH1_k127_2752224_2 Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components K05785 GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000004857 135.0
TH1_k127_2752224_3 transcriptional regulator - - - 0.00000000000000000000000000000001198 129.0
TH1_k127_2772730_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1878.0
TH1_k127_2772730_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1003.0
TH1_k127_2772730_2 Belongs to the CarA family K01956 - 6.3.5.5 4.18e-198 623.0
TH1_k127_2772730_3 Transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 441.0
TH1_k127_2772730_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 296.0
TH1_k127_2772730_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 254.0
TH1_k127_2772730_6 Aspartyl protease - - - 0.0000000000000000000000000002541 118.0
TH1_k127_2772730_7 CRS1_YhbY K07574 - - 0.0000000000000000000000000005233 115.0
TH1_k127_2796826_0 PFAM Major Facilitator Superfamily K08227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 526.0
TH1_k127_2796826_1 Sensors of blue-light using FAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 303.0
TH1_k127_2796826_2 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.000000000000000000000000000000000000000000000000281 183.0
TH1_k127_2796826_3 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.00000000000002057 73.0
TH1_k127_280750_0 POT family K03305 - - 4.925e-196 620.0
TH1_k127_280750_1 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 516.0
TH1_k127_280750_2 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 399.0
TH1_k127_280750_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 361.0
TH1_k127_280750_4 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008723 279.0
TH1_k127_280750_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000009246 173.0
TH1_k127_280750_6 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000001389 159.0
TH1_k127_280750_7 Domain of unknown function (DUF4381) - - - 0.00000000000000000000000002172 111.0
TH1_k127_280750_8 - - - - 0.00000000001114 69.0
TH1_k127_280750_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000466 65.0
TH1_k127_2837425_0 Mechanosensitive ion channel K05802 - - 1.486e-313 994.0
TH1_k127_2837425_1 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 424.0
TH1_k127_2837425_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 347.0
TH1_k127_2881920_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.0 1125.0
TH1_k127_2881920_1 50S ribosome-binding GTPase K06946 - - 7.053e-278 859.0
TH1_k127_2881920_2 50S ribosome-binding GTPase - - - 8.958e-225 699.0
TH1_k127_2881920_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 565.0
TH1_k127_2881920_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
TH1_k127_2881920_5 NlpC/P60 family K13695,K19303 - - 0.000000000000000000000000000000000000002499 154.0
TH1_k127_2881920_6 RNA-binding protein - - - 0.0000000000000000000000000000000006004 132.0
TH1_k127_2881920_7 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 0.0000000000000004524 78.0
TH1_k127_2881920_8 - - - - 0.0000000000006021 73.0
TH1_k127_2953518_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 2.371e-302 930.0
TH1_k127_2953518_1 Cellulose biosynthesis protein BcsQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002748 246.0
TH1_k127_295637_0 DNA RNA helicase - - - 0.0 1803.0
TH1_k127_295637_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1193.0
TH1_k127_295637_2 Phosphate acyltransferases - - - 5.222e-274 862.0
TH1_k127_295637_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 476.0
TH1_k127_295637_4 PFAM SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 469.0
TH1_k127_295637_5 Helix-hairpin-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 458.0
TH1_k127_295637_6 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 418.0
TH1_k127_295637_9 Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation K11373 GO:0000003,GO:0000049,GO:0000123,GO:0000166,GO:0001932,GO:0002097,GO:0002098,GO:0002119,GO:0002164,GO:0002376,GO:0003006,GO:0003008,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004672,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006464,GO:0006468,GO:0006518,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006955,GO:0007154,GO:0007165,GO:0007249,GO:0007252,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007292,GO:0007549,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008023,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008306,GO:0008355,GO:0008607,GO:0009047,GO:0009058,GO:0009059,GO:0009451,GO:0009653,GO:0009790,GO:0009791,GO:0009889,GO:0009987,GO:0009994,GO:0010467,GO:0010468,GO:0010556,GO:0016043,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019207,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019887,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030154,GO:0030234,GO:0030334,GO:0030335,GO:0030554,GO:0031248,GO:0031323,GO:0031326,GO:0031399,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032879,GO:0032991,GO:0033588,GO:0034470,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0040012,GO:0040017,GO:0040025,GO:0040029,GO:0042048,GO:0042221,GO:0042325,GO:0042995,GO:0043005,GO:0043025,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043549,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0045859,GO:0046483,GO:0048232,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048569,GO:0048598,GO:0048599,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051171,GO:0051174,GO:0051246,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051704,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097458,GO:0097659,GO:0098772,GO:0120025,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902493,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2000145,GO:2000147,GO:2001141 - 0.0007442 43.0
TH1_k127_2980830_0 ABC transporter transmembrane region - - - 9.23e-276 858.0
TH1_k127_2980830_1 tryptophan synthase subunit beta - - - 0.000000000000000000000000001203 115.0
TH1_k127_2980830_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000002073 116.0
TH1_k127_2980830_3 response regulator - - - 0.0000000000000000001253 94.0
TH1_k127_3020460_0 reductase 4Fe-4S K00381 - 1.8.1.2 3.602e-287 889.0
TH1_k127_3020460_1 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 599.0
TH1_k127_3020460_2 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 462.0
TH1_k127_3020460_3 Bacterial protein of unknown function (DUF934) - - - 0.0000000000000000000000000002402 119.0
TH1_k127_304075_0 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 486.0
TH1_k127_304075_1 ethanolamine kinase activity K07251 - 2.7.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 455.0
TH1_k127_304075_2 COG0277 FAD FMN-containing dehydrogenases K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 391.0
TH1_k127_304075_3 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002811 248.0
TH1_k127_3048574_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0 1357.0
TH1_k127_3048574_1 Sulfatase - - - 1.247e-221 696.0
TH1_k127_3048574_10 Protein of unknown function (DUF1214) - - - 0.0000000000000000004338 87.0
TH1_k127_3048574_11 DDE superfamily endonuclease - - - 0.000000000003382 69.0
TH1_k127_3048574_13 Protein conserved in bacteria K09914 - - 0.0000008334 55.0
TH1_k127_3048574_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 589.0
TH1_k127_3048574_3 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 433.0
TH1_k127_3048574_4 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 365.0
TH1_k127_3048574_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 294.0
TH1_k127_3048574_6 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006841 236.0
TH1_k127_3048574_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004733 244.0
TH1_k127_3048574_8 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000000000000000000000000000000000000000000000009045 179.0
TH1_k127_3048574_9 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.000000000000000000002109 96.0
TH1_k127_3069148_0 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 473.0
TH1_k127_3069148_1 PFAM 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 452.0
TH1_k127_3069148_10 - - - - 0.0000000000000000000000000000001812 129.0
TH1_k127_3069148_11 - - - - 0.00000000000000000000000003294 115.0
TH1_k127_3069148_2 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 357.0
TH1_k127_3069148_3 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002866 246.0
TH1_k127_3069148_4 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000004861 198.0
TH1_k127_3069148_5 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000001757 185.0
TH1_k127_3069148_6 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000003933 179.0
TH1_k127_3069148_7 MEKHLA domain - - - 0.0000000000000000000000000000000000000000002852 166.0
TH1_k127_3069148_8 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000007453 157.0
TH1_k127_3069148_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000018 129.0
TH1_k127_3069871_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 514.0
TH1_k127_3069871_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 374.0
TH1_k127_3069871_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 293.0
TH1_k127_3069871_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000002456 181.0
TH1_k127_311770_0 M18 family aminopeptidase K01267 - 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 479.0
TH1_k127_311770_1 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000004402 224.0
TH1_k127_3141735_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 501.0
TH1_k127_3141735_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 362.0
TH1_k127_316063_0 AFG1-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 464.0
TH1_k127_316063_1 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 429.0
TH1_k127_316063_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 392.0
TH1_k127_316063_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002696 252.0
TH1_k127_316063_4 PFAM Flavin - - - 0.000000000000000000000000000000000000000000000000000004056 194.0
TH1_k127_316063_5 COG0575 CDP-diglyceride synthetase - - - 0.0000000000000000000000000000000000000000005124 162.0
TH1_k127_316063_6 Rhodanese Homology Domain - - - 0.000000000000000000000000000000003716 135.0
TH1_k127_316063_7 - - - - 0.0000000000000000000000000000002005 127.0
TH1_k127_3211967_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 4.032e-250 783.0
TH1_k127_3211967_1 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000009198 112.0
TH1_k127_3233122_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 299.0
TH1_k127_3233122_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000004237 241.0
TH1_k127_3233122_2 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001507 235.0
TH1_k127_3286982_0 Thymidine phosphorylase K00758 - 2.4.2.4 5.814e-276 856.0
TH1_k127_3286982_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.17e-242 752.0
TH1_k127_3286982_10 PFAM ATPase, F1 V1 A1 complex, alpha beta subunit, nucleotide-binding domain K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000002779 241.0
TH1_k127_3286982_11 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000009347 202.0
TH1_k127_3286982_12 protein conserved in bacteria K09906 - - 0.000000000000000000000000000000000000000000301 165.0
TH1_k127_3286982_13 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000002327 150.0
TH1_k127_3286982_14 - - - - 0.000000000000000000000001781 109.0
TH1_k127_3286982_15 - - - - 0.0000000000001134 74.0
TH1_k127_3286982_16 - - - - 0.00000000002792 73.0
TH1_k127_3286982_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 2.037e-208 653.0
TH1_k127_3286982_3 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 439.0
TH1_k127_3286982_4 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 412.0
TH1_k127_3286982_5 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 400.0
TH1_k127_3286982_6 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 366.0
TH1_k127_3286982_7 PFAM Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 319.0
TH1_k127_3286982_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
TH1_k127_3286982_9 pfam nudix K08312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002566 248.0
TH1_k127_3325703_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 2.613e-273 860.0
TH1_k127_3325703_1 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000000000000000000000000006641 187.0
TH1_k127_3325703_2 Divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000008257 144.0
TH1_k127_3325703_3 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000001212 107.0
TH1_k127_3325703_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000007178 51.0
TH1_k127_3333822_0 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 3.436e-313 970.0
TH1_k127_3333822_1 PFAM Dihydropteroate synthase, DHPS - - - 3.38e-234 732.0
TH1_k127_3333822_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 470.0
TH1_k127_3333822_3 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 332.0
TH1_k127_3333822_4 4-HFC-P synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003245 257.0
TH1_k127_3333822_5 Protein of unknown function (DUF447) K09154 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006113 250.0
TH1_k127_3333822_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000000000000000000001152 227.0
TH1_k127_3333822_7 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000006929 195.0
TH1_k127_3333822_8 PFAM Flavoprotein - - - 0.0000008834 50.0
TH1_k127_3333822_9 Protein of unknown function (DUF2927) - - - 0.0005401 43.0
TH1_k127_3343273_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.068e-296 916.0
TH1_k127_3343273_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 606.0
TH1_k127_3343273_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000001001 133.0
TH1_k127_3476487_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 5.343e-246 772.0
TH1_k127_3476487_1 ATP synthase alpha/beta family, beta-barrel domain K02118 - - 1.497e-238 742.0
TH1_k127_3476487_2 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 559.0
TH1_k127_3476487_3 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 435.0
TH1_k127_3476487_4 Sulfate permease and related transporters (MFS superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 417.0
TH1_k127_3476487_5 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000001939 232.0
TH1_k127_3476487_6 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000001223 209.0
TH1_k127_3476487_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000000000000000000000000000002964 210.0
TH1_k127_3476487_8 Protein of unknown function (DUF2764) - - - 0.00000000000000000000000000000000000000000000008295 176.0
TH1_k127_3520230_0 PFAM N-6 DNA methylase K03427 - 2.1.1.72 1.441e-225 711.0
TH1_k127_3520230_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.168e-218 690.0
TH1_k127_3520230_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 303.0
TH1_k127_3520230_3 ATP synthase K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000001679 242.0
TH1_k127_3520230_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000001181 197.0
TH1_k127_3520230_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000005871 135.0
TH1_k127_3520230_6 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000001247 114.0
TH1_k127_3520230_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000000000008817 109.0
TH1_k127_3525577_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 362.0
TH1_k127_3525577_1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 334.0
TH1_k127_3525577_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000478 126.0
TH1_k127_3525577_3 lytic transglycosylase activity - - - 0.000000000000000000000001062 104.0
TH1_k127_3548320_0 ATP-dependent Clp protease, ATP-binding subunit ClpA K03694 - - 0.0 1148.0
TH1_k127_3548320_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.316e-317 979.0
TH1_k127_3548320_2 Succinate dehydrogenase fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 440.0
TH1_k127_3548320_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000001402 181.0
TH1_k127_3548320_4 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000692 122.0
TH1_k127_3548320_5 succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.0000000000000000008066 91.0
TH1_k127_3548320_6 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000007631 80.0
TH1_k127_3577313_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.675e-296 915.0
TH1_k127_3577313_1 TIGRFAM Coenzyme PQQ biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 5.998e-208 652.0
TH1_k127_3577313_10 TIGRFAM coenzyme PQQ biosynthesis protein PqqD K06138 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000006565 141.0
TH1_k127_3577313_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000007552 126.0
TH1_k127_3577313_12 Putative restriction endonuclease - - - 0.00000000000000000000000008798 109.0
TH1_k127_3577313_13 endonuclease III K01247 - 3.2.2.21 0.000000000002038 68.0
TH1_k127_3577313_14 - - - - 0.00000001974 58.0
TH1_k127_3577313_16 - - - - 0.000005071 50.0
TH1_k127_3577313_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 526.0
TH1_k127_3577313_3 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 461.0
TH1_k127_3577313_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 437.0
TH1_k127_3577313_5 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 372.0
TH1_k127_3577313_6 transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 347.0
TH1_k127_3577313_7 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000000004387 217.0
TH1_k127_3577313_8 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000004335 184.0
TH1_k127_3577313_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000008045 164.0
TH1_k127_358240_0 TIGRFAM ATP-binding cassette protein, ChvD family - - - 2.867e-318 977.0
TH1_k127_358240_1 Heat shock 70 kDa protein K04043 - - 9.732e-212 662.0
TH1_k127_358240_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 7.093e-197 618.0
TH1_k127_358240_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 406.0
TH1_k127_3610778_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 556.0
TH1_k127_3610778_1 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 290.0
TH1_k127_3610778_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000002477 227.0
TH1_k127_3610778_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000002532 124.0
TH1_k127_3687907_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.341e-218 689.0
TH1_k127_3687907_1 SMART Sel1 domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 306.0
TH1_k127_3687907_2 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 291.0
TH1_k127_3687907_3 Belongs to the GSP D family - - - 0.0000000000000000000000000000000000000000000000000000000000005919 223.0
TH1_k127_3697302_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1422.0
TH1_k127_3697302_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000187 157.0
TH1_k127_3728801_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 9.13e-196 614.0
TH1_k127_3728801_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000002766 208.0
TH1_k127_3728801_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000003007 168.0
TH1_k127_37320_0 DNA helicase K03657 - 3.6.4.12 0.0 1046.0
TH1_k127_376383_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1358.0
TH1_k127_376383_1 Polysaccharide biosynthesis protein - - - 6.995e-244 760.0
TH1_k127_376383_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 587.0
TH1_k127_376383_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 538.0
TH1_k127_376383_4 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000002271 143.0
TH1_k127_376383_5 Belongs to the 'phage' integrase family - - - 0.00000000000002057 73.0
TH1_k127_3765998_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.4.2 0.0 1495.0
TH1_k127_3765998_1 UPF0313 protein - - - 1.202e-195 617.0
TH1_k127_3765998_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 524.0
TH1_k127_3765998_3 Glycine cleavage system T protein K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 415.0
TH1_k127_377218_0 Cytochrome c-type biogenesis protein Ccs1 ResB K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 614.0
TH1_k127_377218_1 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 580.0
TH1_k127_377218_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 464.0
TH1_k127_377218_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 293.0
TH1_k127_377218_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 287.0
TH1_k127_377218_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000001989 242.0
TH1_k127_377218_6 Transmembrane protein 260 - - - 0.000000000000000000000000000000111 141.0
TH1_k127_3781746_0 Anion-transporting ATPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 411.0
TH1_k127_3781746_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001446 231.0
TH1_k127_3781746_2 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000000000000000000000000000001734 230.0
TH1_k127_3781746_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000002649 219.0
TH1_k127_3781746_4 - - - - 0.00000000000000000005389 94.0
TH1_k127_3781746_5 Plasmid replication region DNA-binding N-term - - - 0.0000000000000003145 89.0
TH1_k127_3781746_6 - - - - 0.000000000002195 72.0
TH1_k127_3794728_0 MacB-like periplasmic core domain K02004 - - 0.0 1034.0
TH1_k127_3794728_1 SMART Signal transduction response regulator, receiver region - - - 6.625e-238 742.0
TH1_k127_3794728_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 316.0
TH1_k127_3794728_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000003243 185.0
TH1_k127_3800888_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 497.0
TH1_k127_3800888_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 312.0
TH1_k127_3800888_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 - 1.3.1.12,1.3.1.43,2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 278.0
TH1_k127_3800888_3 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000001214 74.0
TH1_k127_3803847_0 Sodium:neurotransmitter symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 328.0
TH1_k127_3803847_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000001064 52.0
TH1_k127_3811864_0 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 596.0
TH1_k127_3811864_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 480.0
TH1_k127_3811864_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 303.0
TH1_k127_3820181_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K01507,K15987 - 3.6.1.1 1.423e-289 905.0
TH1_k127_3820181_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding K01652 - 2.2.1.6 1.121e-202 635.0
TH1_k127_3820181_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000002567 221.0
TH1_k127_3842439_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region K07640 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 461.0
TH1_k127_3842439_1 response regulator K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 291.0
TH1_k127_3842439_2 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000006124 228.0
TH1_k127_3842439_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000003628 183.0
TH1_k127_3842439_4 COG0277 FAD FMN-containing dehydrogenases K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.000000000000000000000000000000000000001444 150.0
TH1_k127_3842439_5 Peptidoglycan-binding protein, CsiV - - - 0.000000000000000000000000004451 119.0
TH1_k127_3842439_6 ATP-independent chaperone mediated protein folding - - - 0.0000000000000001622 89.0
TH1_k127_3884254_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 451.0
TH1_k127_3884254_1 Protein of unknown function (DUF2845) - - - 0.00000000000000000000000000005827 119.0
TH1_k127_3884254_2 TonB-dependent Receptor Plug - - - 0.000000000000009732 74.0
TH1_k127_3973648_0 sh3 domain protein K01448 - 3.5.1.28 0.0000000000000000000000000000000000000001255 155.0
TH1_k127_3973648_1 - - - - 0.0000000000000000000000000000000000002613 146.0
TH1_k127_3973648_2 Lysozyme inhibitor LprI - - - 0.000000000000000000000000000000002156 132.0
TH1_k127_3973648_3 - - - - 0.0000002897 59.0
TH1_k127_3983791_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 475.0
TH1_k127_3983791_1 CHAD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 402.0
TH1_k127_3983791_10 - - - - 0.0003695 46.0
TH1_k127_3983791_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 351.0
TH1_k127_3983791_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000002133 193.0
TH1_k127_3983791_4 GYD domain - - - 0.0000000000000000000000000000001959 125.0
TH1_k127_3983791_5 Immunity protein 53 - - - 0.00000000000000000000000000001254 120.0
TH1_k127_3983791_6 - - - - 0.0000000000000000000000000009976 114.0
TH1_k127_3983791_7 Thioesterase superfamily - - - 0.00000000000000000000001047 110.0
TH1_k127_3983791_8 restriction endonuclease K07448 - - 0.00000000000000000004927 93.0
TH1_k127_3983791_9 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000577 82.0
TH1_k127_4012253_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.101e-251 784.0
TH1_k127_4012253_1 TIGRFAM Ammonia monooxygenase particulate methane monooxygenase, subunit B K10945 - - 1.2e-219 686.0
TH1_k127_4012253_10 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000003307 186.0
TH1_k127_4012253_11 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000001243 186.0
TH1_k127_4012253_12 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000001039 173.0
TH1_k127_4012253_13 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000000006659 139.0
TH1_k127_4012253_14 - - - - 0.0000000000000000000000000000000001259 137.0
TH1_k127_4012253_15 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.0000000000000000000000006911 108.0
TH1_k127_4012253_2 Belongs to the GARS family K01945 - 6.3.4.13 7.819e-203 638.0
TH1_k127_4012253_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 519.0
TH1_k127_4012253_4 methane monooxygenase, subunit C K10946 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 469.0
TH1_k127_4012253_5 TIGRFAM Ammonia monooxygenase particulate methane monooxygenase, subunit A K10944 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.18.3,1.14.99.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 448.0
TH1_k127_4012253_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 414.0
TH1_k127_4012253_7 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 309.0
TH1_k127_4012253_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000002069 258.0
TH1_k127_4012253_9 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000001017 236.0
TH1_k127_402586_0 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 466.0
TH1_k127_402586_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000001626 246.0
TH1_k127_402586_2 - - - - 0.000000000000000000000000000000000000000002105 157.0
TH1_k127_4051917_0 Carbohydrate phosphorylase - - - 0.0 1212.0
TH1_k127_4051917_1 Peptidase U32 K08303 - - 5.944e-232 722.0
TH1_k127_4051917_2 alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 585.0
TH1_k127_4051917_3 Citrate transporter - - - 0.00000000000000000000000000000000002211 135.0
TH1_k127_4093522_0 2-oxoglutarate dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1387.0
TH1_k127_4093522_1 Domain in histone-like proteins of HNS family K03746 - - 0.0000000000000000000000000000006786 126.0
TH1_k127_4093522_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000003193 121.0
TH1_k127_4093522_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000001147 102.0
TH1_k127_4093522_5 - - - - 0.0000003526 53.0
TH1_k127_410202_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 5.981e-249 778.0
TH1_k127_410202_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 432.0
TH1_k127_410202_2 Domain of unknown function (DUF4912) - - - 0.00000000000000000000002236 110.0
TH1_k127_4104113_0 Peptidase family M3 K01414 - 3.4.24.70 0.0 1051.0
TH1_k127_4104113_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.49e-286 884.0
TH1_k127_4104113_2 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 386.0
TH1_k127_4104113_3 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 322.0
TH1_k127_4104113_4 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000000000001214 180.0
TH1_k127_4139614_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 7.646e-264 826.0
TH1_k127_4139614_1 Glycosyl hydrolase family 57 - - - 6.027e-238 743.0
TH1_k127_4139614_2 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 568.0
TH1_k127_4139614_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 446.0
TH1_k127_4139614_4 6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 301.0
TH1_k127_4139614_5 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000000000000000000000000000000000000001841 212.0
TH1_k127_4139614_6 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000000000003228 145.0
TH1_k127_4139614_7 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.000000000000000008997 87.0
TH1_k127_4139614_8 Small metal-binding protein - - - 0.0000000000000003361 81.0
TH1_k127_4143164_0 modulator of DNA gyrase K03592 - - 1.551e-204 644.0
TH1_k127_4143164_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 422.0
TH1_k127_415202_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 548.0
TH1_k127_415202_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000001649 142.0
TH1_k127_4159443_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 332.0
TH1_k127_4159443_1 Pas domain K03320,K11525 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - 0.000000000009172 66.0
TH1_k127_4189732_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2085.0
TH1_k127_4189732_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 379.0
TH1_k127_4189732_2 - - - - 0.0000000000000000000000000003722 116.0
TH1_k127_4189732_3 - - - - 0.000000000000002591 76.0
TH1_k127_4189732_4 - - - - 0.0001812 47.0
TH1_k127_4199010_0 PFAM Glycosyl transferase family 2 - - - 4.953e-270 840.0
TH1_k127_422813_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 405.0
TH1_k127_422813_1 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 346.0
TH1_k127_422813_2 2OG-Fe(II) oxygenase K07394 - - 0.000000000000000000000000000000000000000000000000000000000000000003861 233.0
TH1_k127_422813_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000001386 164.0
TH1_k127_4241147_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 312.0
TH1_k127_4241147_1 COG2206 HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 273.0
TH1_k127_4241147_2 Glycosyl transferases, related to UDP-glucuronosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000236 269.0
TH1_k127_4241147_3 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000008312 245.0
TH1_k127_4241147_4 Protein of unknown function (DUF3455) - - - 0.00000000000000000000000000000000000000000002973 163.0
TH1_k127_4241147_5 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000001436 168.0
TH1_k127_4292018_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 520.0
TH1_k127_4292018_1 signal peptide peptidase SppA K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 441.0
TH1_k127_4292018_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 365.0
TH1_k127_4292018_3 PFAM Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000001393 170.0
TH1_k127_4292018_4 - - - - 0.000003179 53.0
TH1_k127_4300854_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.056e-256 796.0
TH1_k127_4300854_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 358.0
TH1_k127_4300854_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 367.0
TH1_k127_4300854_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 337.0
TH1_k127_4300854_4 Aconitase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 286.0
TH1_k127_4300854_5 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003023 245.0
TH1_k127_4300854_6 (ABC) transporter K02471,K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000175 231.0
TH1_k127_4300854_7 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.0000000000000004413 92.0
TH1_k127_4363332_0 Competence protein ComEC Rec2 K02238 - - 1.118e-220 709.0
TH1_k127_4363332_1 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 1.562e-210 662.0
TH1_k127_4363332_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000001103 201.0
TH1_k127_4363332_11 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000000000000002248 188.0
TH1_k127_4363332_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000000000000000000000971 190.0
TH1_k127_4363332_13 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000001316 114.0
TH1_k127_4363332_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 9.262e-200 631.0
TH1_k127_4363332_3 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 408.0
TH1_k127_4363332_4 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 292.0
TH1_k127_4363332_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001059 265.0
TH1_k127_4363332_6 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000001603 228.0
TH1_k127_4363332_7 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005103 236.0
TH1_k127_4363332_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000002785 223.0
TH1_k127_4363332_9 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000006863 215.0
TH1_k127_4391196_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 524.0
TH1_k127_4391196_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 328.0
TH1_k127_4391196_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000001584 89.0
TH1_k127_4430908_0 Lycopene cyclase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 516.0
TH1_k127_4430908_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 466.0
TH1_k127_4430908_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 434.0
TH1_k127_4430908_3 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000008509 160.0
TH1_k127_4430908_4 - - - - 0.00000000000000000000004314 105.0
TH1_k127_4430908_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000001889 79.0
TH1_k127_444166_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 601.0
TH1_k127_444166_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 487.0
TH1_k127_444166_2 PFAM Staphylococcal nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006742 266.0
TH1_k127_444166_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000001266 201.0
TH1_k127_4459050_0 Enoyl-CoA hydratase/isomerase - - - 3.97e-215 680.0
TH1_k127_4459050_1 acyl-CoA dehydrogenase K06445 GO:0003674,GO:0003824,GO:0003995,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 - 0.0000000000001316 74.0
TH1_k127_4467949_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 0.0 1173.0
TH1_k127_4467949_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 451.0
TH1_k127_4467949_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 436.0
TH1_k127_4467949_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 422.0
TH1_k127_4467949_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000005422 208.0
TH1_k127_4467949_5 - - - - 0.0000000000000000000000002091 109.0
TH1_k127_4467949_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000003548 104.0
TH1_k127_4467949_7 - - - - 0.0000004037 55.0
TH1_k127_4518788_0 CHASE4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 386.0
TH1_k127_4518788_1 HAMAP Peptide methionine sulfoxide reductase msrB K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001839 234.0
TH1_k127_4518788_2 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001204 228.0
TH1_k127_4518788_3 M18 family aminopeptidase K01267 - 3.4.11.21 0.00000000000000000000000000000000338 132.0
TH1_k127_4518788_4 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region K20974 - 2.7.13.3 0.0000000000000000000001036 102.0
TH1_k127_4533991_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 451.0
TH1_k127_4533991_1 deaminase zinc-binding - - - 0.000000000000000000000000000000000000000000000000000000000003622 211.0
TH1_k127_4533991_2 Cupin domain - - - 0.00000000000000000000000000000000000001599 149.0
TH1_k127_4566743_0 SMART ATPase, AAA type, core K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 467.0
TH1_k127_4566743_1 Type II secretion system protein B K02451 - - 0.00000000007122 72.0
TH1_k127_4582299_0 DNA helicase K03654 - 3.6.4.12 1.166e-264 823.0
TH1_k127_4582299_1 Type I restriction-modification system K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 598.0
TH1_k127_4582299_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 440.0
TH1_k127_4582299_3 PIN domain - - - 0.000000000000000000000000000000000000000293 153.0
TH1_k127_4582299_4 nucleic acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000000000002067 147.0
TH1_k127_4582299_5 - - - - 0.00000000000000000000000797 102.0
TH1_k127_4582299_6 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000000005135 99.0
TH1_k127_4597897_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1133.0
TH1_k127_4597897_1 AAA-like domain K06915 - - 3.676e-303 935.0
TH1_k127_4597897_2 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 372.0
TH1_k127_4597897_3 Aldolase K01624 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000005154 244.0
TH1_k127_4613760_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 494.0
TH1_k127_4613760_1 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000000000000000000006147 209.0
TH1_k127_4613760_2 Alpha/beta hydrolase family - - - 0.000001261 59.0
TH1_k127_461921_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 456.0
TH1_k127_461921_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 409.0
TH1_k127_461921_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000005384 177.0
TH1_k127_461921_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000003482 59.0
TH1_k127_4668211_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.107e-202 634.0
TH1_k127_4668211_1 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 455.0
TH1_k127_4668211_2 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 403.0
TH1_k127_4672544_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 456.0
TH1_k127_4672544_1 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0000000000000000000000000000000000000000007983 159.0
TH1_k127_4672544_2 PFAM Ferrous iron transporter, FeoA subunit K04758 - - 0.000000000000000000000000000004853 121.0
TH1_k127_4712002_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.84e-239 747.0
TH1_k127_4712002_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 283.0
TH1_k127_4712002_2 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000003062 70.0
TH1_k127_4712002_3 Formiminotransferase-cyclodeaminase - - - 0.0000682 47.0
TH1_k127_4712114_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 509.0
TH1_k127_4712114_1 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 404.0
TH1_k127_4712114_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 365.0
TH1_k127_4712114_3 Cytochrome c K02305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 355.0
TH1_k127_4712114_4 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 283.0
TH1_k127_4712114_5 - - - - 0.000000000000000000000000000000000000000000002391 167.0
TH1_k127_4724286_0 Proton-conducting membrane transporter - - - 6.227e-255 803.0
TH1_k127_4724286_1 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001945 244.0
TH1_k127_4763343_0 Cytochrome P450 K05917 - 1.14.13.70 3.891e-212 673.0
TH1_k127_4763343_1 TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 576.0
TH1_k127_4763343_2 - - - - 0.00000000000000000000000000000000000000000000000000000000001887 218.0
TH1_k127_4767018_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 572.0
TH1_k127_4767018_1 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 330.0
TH1_k127_4767018_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000001577 205.0
TH1_k127_4767018_3 PFAM Small Multidrug Resistance protein K11741 - - 0.00000000000000000000000000000000000000000007855 161.0
TH1_k127_4767018_4 TIGRFAM Sulphur relay, TusB DsrH K07237 - - 0.0000000000000000916 83.0
TH1_k127_4783762_0 AIR synthase related protein, C-terminal K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 539.0
TH1_k127_4783762_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 484.0
TH1_k127_4783762_2 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 460.0
TH1_k127_4783762_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 444.0
TH1_k127_4783762_4 Tyrosine-protein kinase, subgroup, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 421.0
TH1_k127_4783762_5 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 345.0
TH1_k127_4783762_6 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004834 274.0
TH1_k127_4783762_7 Domains REC, sigma54 interaction, HTH8 K20919 - - 0.0000000000000000000000000000000000000000000000000000000000002897 220.0
TH1_k127_4783762_8 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000000000000002839 158.0
TH1_k127_4783762_9 - - - - 0.00000000000000000000133 100.0
TH1_k127_4800785_0 Cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 428.0
TH1_k127_4800785_1 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002238 247.0
TH1_k127_4800785_2 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000001777 163.0
TH1_k127_4832446_0 UvrD-like helicase C-terminal domain K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 366.0
TH1_k127_4844743_0 PFAM Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 476.0
TH1_k127_4844743_1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 463.0
TH1_k127_4844743_2 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 402.0
TH1_k127_4852683_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 7.918e-258 799.0
TH1_k127_4852683_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 5.614e-197 617.0
TH1_k127_4852683_2 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 351.0
TH1_k127_4852683_3 VanZ like family - - - 0.0000000000000000000000000000004601 126.0
TH1_k127_4852683_4 PFAM Transposase, IS4-like - - - 0.00000000002378 66.0
TH1_k127_4852683_5 PFAM PilT protein, N-terminal - - - 0.0005003 45.0
TH1_k127_4945860_0 GTP-binding protein TypA K06207 - - 0.0 1046.0
TH1_k127_4945860_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 264.0
TH1_k127_4945860_2 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000001663 203.0
TH1_k127_4945860_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000002149 199.0
TH1_k127_4948970_0 Belongs to the 5'-nucleotidase family - - - 9.473e-224 706.0
TH1_k127_4948970_1 Beta-Casp domain K07576 - - 6.038e-215 675.0
TH1_k127_4948970_2 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 336.0
TH1_k127_4948970_3 COG0480 Translation elongation factors (GTPases) K02355 - - 0.0000000000001539 71.0
TH1_k127_4948970_4 - catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000807 66.0
TH1_k127_5021361_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 513.0
TH1_k127_5021361_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 438.0
TH1_k127_5021361_2 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 319.0
TH1_k127_5021361_3 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004685 239.0
TH1_k127_5021361_4 Regulatory protein, FmdB family - - - 0.0000000000000000000000000000000000000001236 151.0
TH1_k127_5023578_0 PFAM Glycoside hydrolase, family 3, N-terminal K05349 - 3.2.1.21 0.0 1030.0
TH1_k127_5023578_1 Transport of potassium into the cell K03549 - - 4.429e-282 876.0
TH1_k127_5023578_2 PFAM FAD linked oxidase domain protein K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 2.919e-213 672.0
TH1_k127_5023578_3 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 3.471e-199 636.0
TH1_k127_5023578_4 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 344.0
TH1_k127_5023578_5 PFAM Uncharacterised protein family UPF0029, Impact, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000008097 226.0
TH1_k127_5023578_6 - - - - 0.00000000000000000000000000000000000307 141.0
TH1_k127_5041958_0 Enoyl-CoA hydratase/isomerase - - - 3.959e-301 930.0
TH1_k127_5041958_1 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 497.0
TH1_k127_5041958_2 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 407.0
TH1_k127_5041958_3 Transcriptional regulator K03717 - - 0.000000000000000003174 85.0
TH1_k127_5041958_4 - - - - 0.00000000000007345 72.0
TH1_k127_5042007_0 PFAM Binding-protein-dependent transport systems inner membrane component K02037 - - 0.0 1023.0
TH1_k127_5042007_1 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 499.0
TH1_k127_5042007_2 Phosphate transport system permease protein K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 346.0
TH1_k127_5042007_3 Transcriptional regulator K03717 - - 0.000000000000000000891 87.0
TH1_k127_5042239_0 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1487.0
TH1_k127_5063347_0 COG4585 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003126 299.0
TH1_k127_5063347_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000009482 228.0
TH1_k127_5085917_0 Helix-turn-helix XRE-family like proteins K18831 - - 0.00000000000000000000000000000000000000000000000000000008406 198.0
TH1_k127_5085917_1 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000000000000000000000000000006707 152.0
TH1_k127_5085917_2 Protein conserved in bacteria - - - 0.0000000000000000000000000001699 116.0
TH1_k127_5085917_3 PFAM GCN5-related N-acetyltransferase - - - 0.00002308 50.0
TH1_k127_5094454_0 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 1.277e-262 824.0
TH1_k127_5094454_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 412.0
TH1_k127_5094454_2 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 398.0
TH1_k127_5094454_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001008 283.0
TH1_k127_5094454_4 PFAM Uncharacterised protein family UPF0079, ATPase bacteria K06925 - - 0.00000000000000000000000000000000000000000000000003489 182.0
TH1_k127_5105445_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.336e-313 970.0
TH1_k127_5105445_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 560.0
TH1_k127_5105445_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 504.0
TH1_k127_5105445_3 chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 440.0
TH1_k127_5105445_4 Competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004933 274.0
TH1_k127_5105445_6 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000003757 173.0
TH1_k127_5105445_7 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000001222 110.0
TH1_k127_5108472_0 TIGRFAM PQQ-dependent catabolism-associated beta-propeller protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 479.0
TH1_k127_5108472_1 TIGRFAM alcohol ABC transporter, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 441.0
TH1_k127_5108472_2 TIGRFAM ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 428.0
TH1_k127_5108472_3 TIGRFAM ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 342.0
TH1_k127_5108472_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 284.0
TH1_k127_5114454_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 4.73e-272 849.0
TH1_k127_5114454_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 572.0
TH1_k127_5114454_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 502.0
TH1_k127_5114454_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 317.0
TH1_k127_5114454_4 TIGRFAM Lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008385 275.0
TH1_k127_5114454_5 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.00000000000000000000000000000000000000000000000000002912 192.0
TH1_k127_5138902_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 476.0
TH1_k127_5138902_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 434.0
TH1_k127_5138902_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 318.0
TH1_k127_5138902_3 ribonuclease activity - - - 0.00000000000000000000000000000000000000006967 155.0
TH1_k127_5138902_4 - - - - 0.00000000000000927 76.0
TH1_k127_5138902_5 - - - - 0.00000000000004329 74.0
TH1_k127_51484_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1298.0
TH1_k127_5148953_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 526.0
TH1_k127_5148953_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 392.0
TH1_k127_5148953_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000004096 260.0
TH1_k127_5148953_3 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000007019 173.0
TH1_k127_5179972_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1101.0
TH1_k127_5179972_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000004397 226.0
TH1_k127_5179972_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000268 188.0
TH1_k127_51833_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 368.0
TH1_k127_51833_1 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000004105 173.0
TH1_k127_5186129_0 Fatty acid cis/trans isomerase (CTI) - - - 4.095e-288 906.0
TH1_k127_5190894_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 1.475e-237 745.0
TH1_k127_5190894_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 494.0
TH1_k127_5190894_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 363.0
TH1_k127_5190894_3 universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 351.0
TH1_k127_5190894_4 - - - - 0.0000000000000000000000001616 105.0
TH1_k127_5190894_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000007298 50.0
TH1_k127_5192238_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1427.0
TH1_k127_5192238_1 AI-2E family transporter K03548 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 451.0
TH1_k127_5192238_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
TH1_k127_5192238_3 Bacterial periplasmic substrate-binding proteins - - - 0.000000004123 67.0
TH1_k127_5194005_0 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 426.0
TH1_k127_5194005_1 Acyl- acyl-carrier-protein --UDP-N-acetylglucosamine O-acyltransferase K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 406.0
TH1_k127_5194005_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000003982 186.0
TH1_k127_5194005_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000002616 151.0
TH1_k127_5194005_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000001547 144.0
TH1_k127_5194005_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000002041 78.0
TH1_k127_5228016_0 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 516.0
TH1_k127_5228016_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 473.0
TH1_k127_5228016_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 441.0
TH1_k127_5228016_3 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 327.0
TH1_k127_5228016_4 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 286.0
TH1_k127_5271696_0 50S ribosome-binding GTPase - - - 5.845e-198 632.0
TH1_k127_5271696_1 synthase component I K01665 - 2.6.1.85 3.246e-197 625.0
TH1_k127_5271696_10 - - - - 0.00000000000000000000000000000006505 131.0
TH1_k127_5271696_11 ATP-grasp domain - - - 0.00000000000001593 75.0
TH1_k127_5271696_12 DDE superfamily endonuclease - - - 0.0000000000007203 71.0
TH1_k127_5271696_2 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 524.0
TH1_k127_5271696_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 387.0
TH1_k127_5271696_4 50S ribosome-binding GTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 387.0
TH1_k127_5271696_5 PFAM Hydantoinase oxoprolinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 342.0
TH1_k127_5271696_6 Protein of unknown function (DUF2959) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009566 243.0
TH1_k127_5271696_7 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000003204 236.0
TH1_k127_5271696_8 - - - - 0.00000000000000000000000000000000000000000000000000000000007912 211.0
TH1_k127_5271696_9 Amino acid kinase family - - - 0.000000000000000000000000000000000000000007392 167.0
TH1_k127_5283106_0 S1, RNA binding domain K06959 - - 0.0 1124.0
TH1_k127_5283106_1 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 2.07e-238 753.0
TH1_k127_5283106_10 - - - - 0.0000000000000000000000000000000502 130.0
TH1_k127_5283106_11 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000001297 123.0
TH1_k127_5283106_12 - - - - 0.000000000000000000000041 105.0
TH1_k127_5283106_13 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000005795 84.0
TH1_k127_5283106_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 515.0
TH1_k127_5283106_3 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 396.0
TH1_k127_5283106_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 390.0
TH1_k127_5283106_5 P-loop containing region of AAA domain K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 274.0
TH1_k127_5283106_6 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003071 269.0
TH1_k127_5283106_7 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007092 272.0
TH1_k127_5283106_8 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000002349 192.0
TH1_k127_5283106_9 Cupin domain K11312 - - 0.00000000000000000000000000000000228 134.0
TH1_k127_5284458_0 ABC transporter K06158 - - 4.143e-243 760.0
TH1_k127_5284458_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 522.0
TH1_k127_5284458_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 285.0
TH1_k127_5284458_3 YcxB-like protein - - - 0.0000000000000000000000000000000000000000000000000000001418 200.0
TH1_k127_5284458_4 Protein of unknown function (DUF2782) - - - 0.00000000000000000000000000000000008749 136.0
TH1_k127_5284458_5 Protein of unknown function (DUF721) - - - 0.0000000000000002008 85.0
TH1_k127_5290294_0 Lipase maturation factor - - - 4.148e-201 638.0
TH1_k127_5290294_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 434.0
TH1_k127_5290294_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 324.0
TH1_k127_5290294_3 - - - - 0.000000000000000000000000000000000000001893 150.0
TH1_k127_5290294_4 Glycine-zipper domain - - - 0.000000000000000000007812 94.0
TH1_k127_5290294_5 Fatty acid desaturase - - - 0.000002092 49.0
TH1_k127_5290294_6 Protein of unknown function (DUF1254) - - - 0.00005972 45.0
TH1_k127_5316277_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 606.0
TH1_k127_5316277_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 539.0
TH1_k127_5316277_2 Belongs to the bacterial glucokinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 358.0
TH1_k127_5316277_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006311 270.0
TH1_k127_5316277_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001346 263.0
TH1_k127_5316277_5 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000001811 200.0
TH1_k127_5316277_6 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000000000000000005305 194.0
TH1_k127_53204_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.026e-200 636.0
TH1_k127_53204_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 8.892e-197 618.0
TH1_k127_53204_2 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 428.0
TH1_k127_53204_3 Permease YjgP YjgQ K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 378.0
TH1_k127_53204_4 PFAM DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.0000000000000000000000000000000000000002686 153.0
TH1_k127_53204_6 RDD family - - - 0.000000002484 59.0
TH1_k127_5328530_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 538.0
TH1_k127_5328530_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 538.0
TH1_k127_5328530_2 PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 366.0
TH1_k127_5328530_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 313.0
TH1_k127_5328530_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000004267 220.0
TH1_k127_5328530_5 ABC transporter transmembrane region K06148 - - 0.000000000000000000000000000000000000000000000000000000000003361 209.0
TH1_k127_5360456_0 Soluble lytic murein transglycosylase L domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 392.0
TH1_k127_5360456_1 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 317.0
TH1_k127_5360456_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000003957 173.0
TH1_k127_5371679_0 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 346.0
TH1_k127_5371679_1 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000000009413 195.0
TH1_k127_5371679_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000006368 146.0
TH1_k127_5371679_3 Glycine-zipper domain - - - 0.0000000000000000000007556 101.0
TH1_k127_5372981_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1025.0
TH1_k127_5372981_1 Copper resistance K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 480.0
TH1_k127_5372981_2 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000001063 260.0
TH1_k127_5372981_3 Pirin K06911 - - 0.000000000000000000000000000000002249 131.0
TH1_k127_538591_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2078.0
TH1_k127_538591_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.125e-255 791.0
TH1_k127_538591_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
TH1_k127_538591_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000008574 234.0
TH1_k127_54016_0 Protein conserved in bacteria K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 487.0
TH1_k127_54016_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 397.0
TH1_k127_5403017_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1136.0
TH1_k127_5403017_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000187 180.0
TH1_k127_5422457_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 526.0
TH1_k127_5422457_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 316.0
TH1_k127_5422457_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 291.0
TH1_k127_5422457_3 - - - - 0.000000000000000000000000000000000000001509 150.0
TH1_k127_5422457_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000001689 97.0
TH1_k127_5422457_5 PFAM Transposase IS200 like K07491 - - 0.000000000000000001296 87.0
TH1_k127_5432099_0 PFAM Major Facilitator Superfamily K02575 - - 2.075e-225 706.0
TH1_k127_5432099_1 kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 306.0
TH1_k127_5432099_2 Alginate export - - - 0.00000000000000000005519 91.0
TH1_k127_5432693_0 PFAM ATPase, F1 V1 A1 complex, alpha beta subunit, nucleotide-binding domain K02112 - 3.6.3.14 1.864e-223 697.0
TH1_k127_5432693_1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.0000000000000000000000000000000000000000000004132 170.0
TH1_k127_5445013_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 463.0
TH1_k127_5445013_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 313.0
TH1_k127_5445013_2 Membrane K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001294 255.0
TH1_k127_5449736_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.271e-301 934.0
TH1_k127_5449736_1 Oxidoreductase NAD-binding domain K00523,K21832 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 442.0
TH1_k127_5449736_2 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 412.0
TH1_k127_5449736_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
TH1_k127_5449736_4 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000000000000000000000000008412 179.0
TH1_k127_5449736_5 Sporulation related domain - - - 0.0000000000000000000000000000000000000000003624 164.0
TH1_k127_5449736_6 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000002711 174.0
TH1_k127_5449736_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000001165 83.0
TH1_k127_5449736_8 transferase activity, transferring hexosyl groups K05841 - 2.4.1.173 0.0004082 44.0
TH1_k127_5455833_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1875.0
TH1_k127_5455833_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1098.0
TH1_k127_5455833_10 PFAM PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 475.0
TH1_k127_5455833_11 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 483.0
TH1_k127_5455833_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 451.0
TH1_k127_5455833_13 DnaJ-class molecular chaperone K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 437.0
TH1_k127_5455833_14 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 434.0
TH1_k127_5455833_15 Putative ATP-dependent Lon protease K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 406.0
TH1_k127_5455833_16 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 370.0
TH1_k127_5455833_17 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 347.0
TH1_k127_5455833_18 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 309.0
TH1_k127_5455833_19 SCP-2 sterol transfer family K03690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001431 244.0
TH1_k127_5455833_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 7.493e-265 822.0
TH1_k127_5455833_20 - - - - 0.000000000000000000000000000000000000000000000000000000001026 207.0
TH1_k127_5455833_21 - - - - 0.00000000000000000000000000000000000000000000000000000009118 201.0
TH1_k127_5455833_22 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000876 196.0
TH1_k127_5455833_23 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000001034 191.0
TH1_k127_5455833_24 protein conserved in bacteria K09912 - - 0.000000000000000000000000000000000000000000000003706 178.0
TH1_k127_5455833_25 - - - - 0.00000000000000000000000000000000000000000000001644 176.0
TH1_k127_5455833_26 Beta/Gamma crystallin - - - 0.0000000000000000000000000000000001664 138.0
TH1_k127_5455833_27 MerR HTH family regulatory protein K18997 - - 0.00000000000000000000000000004652 119.0
TH1_k127_5455833_28 - - - - 0.000000000000000000000000001017 117.0
TH1_k127_5455833_29 Phosphate transport regulator - - - 0.00000000000000001121 91.0
TH1_k127_5455833_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.632e-242 755.0
TH1_k127_5455833_30 TIGRFAM Thioredoxin K03672 - 1.8.1.8 0.00000000000007684 73.0
TH1_k127_5455833_31 - - - - 0.00000003288 63.0
TH1_k127_5455833_4 Protein of unknown function (DUF1343) - - - 4.494e-226 705.0
TH1_k127_5455833_5 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 4.796e-225 706.0
TH1_k127_5455833_6 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.248e-223 699.0
TH1_k127_5455833_7 Sporulation related domain K16291 - - 3.92e-198 627.0
TH1_k127_5455833_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 577.0
TH1_k127_5455833_9 epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 495.0
TH1_k127_5462533_0 Belongs to the GPI family K01810 - 5.3.1.9 3.68e-266 830.0
TH1_k127_5462533_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 410.0
TH1_k127_5462533_2 PFAM multicopper oxidase type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 359.0
TH1_k127_5462533_3 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 342.0
TH1_k127_5462533_4 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 284.0
TH1_k127_5462533_5 - - - - 0.000000000000000000000000000000000000000000000000000000000001959 214.0
TH1_k127_5462533_6 Membrane - - - 0.0000000000000000000000000000000000000000000003446 170.0
TH1_k127_5462533_7 Glycosyl transferases group 1 K02844 - - 0.0000004394 53.0
TH1_k127_55173_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.063e-278 861.0
TH1_k127_55173_1 Multicopper oxidase - - - 5.016e-231 733.0
TH1_k127_55173_10 - - - - 0.0000000000000000000000000000000000006332 141.0
TH1_k127_55173_11 Cytochrome c - - - 0.0000000000000000000000000000001162 128.0
TH1_k127_55173_12 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000005141 114.0
TH1_k127_55173_13 Protein of unknown function (DUF2905) - - - 0.0000000000000000000000002457 106.0
TH1_k127_55173_2 Required for chromosome condensation and partitioning K03529 - - 1.015e-206 659.0
TH1_k127_55173_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 563.0
TH1_k127_55173_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 462.0
TH1_k127_55173_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 384.0
TH1_k127_55173_6 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 372.0
TH1_k127_55173_7 Copper resistance protein B precursor (CopB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 363.0
TH1_k127_55173_8 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000006839 246.0
TH1_k127_55173_9 PilZ domain - - - 0.00000000000000000000000000000000000000000000000001001 188.0
TH1_k127_5532279_0 TIGRFAM Lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 404.0
TH1_k127_5532279_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 394.0
TH1_k127_5532279_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 383.0
TH1_k127_5555686_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1106.0
TH1_k127_5555686_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1088.0
TH1_k127_5555686_2 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 606.0
TH1_k127_5555686_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 570.0
TH1_k127_5555686_4 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 284.0
TH1_k127_5555686_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002209 270.0
TH1_k127_5555686_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000002149 192.0
TH1_k127_5555686_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000006391 116.0
TH1_k127_5555686_8 - - - - 0.0000000000000000000000001996 111.0
TH1_k127_5559660_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 324.0
TH1_k127_5559660_1 - - - - 0.000000000000000000000000000000000000000009225 156.0
TH1_k127_5559660_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000003082 126.0
TH1_k127_55720_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2243.0
TH1_k127_55720_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 594.0
TH1_k127_55720_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001625 269.0
TH1_k127_5606880_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 508.0
TH1_k127_5606880_1 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000003704 134.0
TH1_k127_5606880_2 paraquat-inducible protein b K06192 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016020,GO:0016021,GO:0016043,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0071944,GO:0120009 - 0.0000000000001222 72.0
TH1_k127_5644808_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 585.0
TH1_k127_5644808_1 Cysteine-rich domain K11473 - - 0.000000000000000000000008633 101.0
TH1_k127_5644808_2 Cysteine-rich domain K11473 - - 0.000000000002251 68.0
TH1_k127_570335_0 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 424.0
TH1_k127_570335_1 PFAM Polyketide cyclase dehydrase K16260 - - 0.000000000000000000000000000000000000000000000000000000000000000000003124 240.0
TH1_k127_570335_2 PIN domain - - - 0.0000000000000000000000000000003211 126.0
TH1_k127_570335_3 - - - - 0.00000000000000000000000001052 109.0
TH1_k127_570335_4 protein conserved in bacteria K01790 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 0.000000000000000000000002387 105.0
TH1_k127_570335_5 Protein of unknown function (DUF455) - - - 0.0000000000000982 72.0
TH1_k127_570335_6 Helix-turn-helix domain - - - 0.00003664 51.0
TH1_k127_57419_0 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 575.0
TH1_k127_57419_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 350.0
TH1_k127_57419_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 351.0
TH1_k127_57419_3 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 314.0
TH1_k127_57419_4 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 287.0
TH1_k127_5745485_0 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
TH1_k127_5745485_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000001932 201.0
TH1_k127_5745485_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000001655 153.0
TH1_k127_5745485_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000003972 112.0
TH1_k127_5745485_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.0000000005384 63.0
TH1_k127_5752668_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1467.0
TH1_k127_5752668_1 Phage late control gene D protein (GPD) K11904 - - 2.839e-291 903.0
TH1_k127_5752668_2 Type VI secretion, TssG K11895 - - 0.0000000000000006933 77.0
TH1_k127_5754925_0 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 554.0
TH1_k127_5754925_3 Domain of unknown function (DUF1840) - - - 0.000000000000000000000000000001438 123.0
TH1_k127_5754925_4 - - - - 0.000000000000000000005552 94.0
TH1_k127_5760319_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.319e-255 801.0
TH1_k127_5760319_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 441.0
TH1_k127_5760319_2 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000000000001322 166.0
TH1_k127_5760319_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000003325 142.0
TH1_k127_5781699_0 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 380.0
TH1_k127_5781699_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
TH1_k127_5781699_2 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000007286 243.0
TH1_k127_5781699_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
TH1_k127_5781699_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001588 233.0
TH1_k127_5793934_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.187e-207 649.0
TH1_k127_5793934_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 573.0
TH1_k127_5793934_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 476.0
TH1_k127_5793934_3 Bacterial SH3 domain homologues K07184 - - 0.0000000000000000000000000000000000000000000000000000000004383 211.0
TH1_k127_5793934_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000007748 174.0
TH1_k127_5793934_5 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.000000000000000000000000000000000000000000000009583 173.0
TH1_k127_5832750_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.938e-260 809.0
TH1_k127_5832750_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.571e-234 734.0
TH1_k127_5832750_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000009992 259.0
TH1_k127_5832750_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001448 244.0
TH1_k127_5832750_12 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000007943 233.0
TH1_k127_5832750_13 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000004278 206.0
TH1_k127_5832750_14 - - - - 0.00000000000000000000000000000000000004679 144.0
TH1_k127_5832750_15 - - - - 0.0000000000000000000000000000000717 133.0
TH1_k127_5832750_16 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000001296 98.0
TH1_k127_5832750_17 - - - - 0.00000000000001078 78.0
TH1_k127_5832750_18 rRNA methylase - - - 0.00000000000002762 75.0
TH1_k127_5832750_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 2.383e-213 665.0
TH1_k127_5832750_3 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 611.0
TH1_k127_5832750_4 PFAM Alpha-D-phosphohexomutase, alpha beta alpha domain I K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 555.0
TH1_k127_5832750_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 534.0
TH1_k127_5832750_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 467.0
TH1_k127_5832750_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 390.0
TH1_k127_5832750_8 PFAM Formaldehyde-activating enzyme (Fae) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 321.0
TH1_k127_5832750_9 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 314.0
TH1_k127_5834532_0 BT1 family - - - 1.235e-216 687.0
TH1_k127_5901930_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 357.0
TH1_k127_5901930_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007722 246.0
TH1_k127_5901930_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000007623 226.0
TH1_k127_5901930_3 Belongs to the GcvT family K06980 - - 0.00000948 50.0
TH1_k127_590608_0 Domain of unknown function (DUF1974) - - - 3.695e-257 799.0
TH1_k127_593619_0 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 533.0
TH1_k127_593619_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 445.0
TH1_k127_593619_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 427.0
TH1_k127_593619_3 MlaD protein K06192 - - 0.0000000000000000000000000000000000003485 144.0
TH1_k127_5970526_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.481e-237 737.0
TH1_k127_5970526_1 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 556.0
TH1_k127_5970526_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 481.0
TH1_k127_5970526_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000003567 216.0
TH1_k127_5970526_4 PFAM Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000009086 203.0
TH1_k127_5970526_5 Sporulation related domain K03749 - - 0.0000000000000000000000009219 115.0
TH1_k127_600633_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K17686 - 3.6.3.54 0.0 1054.0
TH1_k127_600633_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 384.0
TH1_k127_600633_2 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 329.0
TH1_k127_600633_3 High frequency lysogenization protein HflD homolog K07153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 284.0
TH1_k127_600633_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002158 267.0
TH1_k127_600633_5 Heavy-metal-associated domain K07213 - - 0.000000000000002566 77.0
TH1_k127_600633_6 ABC-type uncharacterized transport system - - - 0.0007364 48.0
TH1_k127_6022558_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 5.196e-247 766.0
TH1_k127_6022558_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 525.0
TH1_k127_6022558_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 486.0
TH1_k127_6022558_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 469.0
TH1_k127_6022558_4 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 465.0
TH1_k127_6022558_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 379.0
TH1_k127_6022558_6 NfeD-like C-terminal, partner-binding K07340 - - 0.0000000000000000000000000000000000000000000000000000001259 198.0
TH1_k127_6022558_7 - - - - 0.00000000000525 70.0
TH1_k127_6022558_8 - - - - 0.00005441 46.0
TH1_k127_6026027_0 heat shock protein DnaJ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 398.0
TH1_k127_6026027_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 364.0
TH1_k127_6026027_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000004902 207.0
TH1_k127_6026027_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000001761 127.0
TH1_k127_6087631_0 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000001488 221.0
TH1_k127_6087631_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000245 193.0
TH1_k127_6087631_2 membrane - - - 0.000000000000000003855 87.0
TH1_k127_6087631_3 Protein of unknown function (DUF1249) K09920 - - 0.00000000000229 68.0
TH1_k127_6087631_4 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.00000008257 58.0
TH1_k127_6094407_0 Signal transduction histidine kinase K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 478.0
TH1_k127_6094407_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 367.0
TH1_k127_6094407_2 Nitrogen regulation K07712 - - 0.000000000000000000000000000000000007585 138.0
TH1_k127_6094407_3 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000008019 51.0
TH1_k127_6104036_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 2.732e-231 720.0
TH1_k127_6104036_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 7.457e-224 697.0
TH1_k127_6104036_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 8.368e-216 677.0
TH1_k127_6104036_3 Exonuclease C-terminal K01141 - 3.1.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 586.0
TH1_k127_6104036_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 445.0
TH1_k127_6104036_5 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 396.0
TH1_k127_6104036_6 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0055114 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 367.0
TH1_k127_6104036_7 Glutamyl glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 360.0
TH1_k127_6104036_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000005676 179.0
TH1_k127_6104036_9 (Na+)-NQR maturation NqrM K05952 - - 0.000000000000001054 81.0
TH1_k127_6104114_0 transcriptional regulator K21405 - - 9.944e-274 852.0
TH1_k127_6104114_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001143 273.0
TH1_k127_6119122_0 glutamate--cysteine ligase - - - 2.933e-216 680.0
TH1_k127_6119122_1 succinylglutamate desuccinylase activity K05526 - 3.5.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 489.0
TH1_k127_6119122_2 Domain of unknown function (DUF1974) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 375.0
TH1_k127_6119122_3 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002483 254.0
TH1_k127_6127543_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0 1802.0
TH1_k127_6127543_1 TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.0 1076.0
TH1_k127_6127543_10 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006118 267.0
TH1_k127_6127543_11 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002454 252.0
TH1_k127_6127543_12 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19 0.000000000000000000000000000000000000000000000000000000000000008037 221.0
TH1_k127_6127543_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000003237 194.0
TH1_k127_6127543_14 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000001229 185.0
TH1_k127_6127543_15 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.000000000000000000000000000000000000000000000653 167.0
TH1_k127_6127543_16 Fic/DOC family - - - 0.0000000000000000000000000000000000174 145.0
TH1_k127_6127543_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000001006 112.0
TH1_k127_6127543_18 Protein of unknown function (DUF2892) - - - 0.000000000000000000005507 97.0
TH1_k127_6127543_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - 0.000000000002877 68.0
TH1_k127_6127543_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 2.635e-212 666.0
TH1_k127_6127543_20 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000007717 57.0
TH1_k127_6127543_3 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 554.0
TH1_k127_6127543_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 460.0
TH1_k127_6127543_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 415.0
TH1_k127_6127543_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 381.0
TH1_k127_6127543_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 362.0
TH1_k127_6127543_8 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 332.0
TH1_k127_6127543_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 316.0
TH1_k127_6146992_0 Nitroreductase family - - - 2.023e-198 631.0
TH1_k127_6146992_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000006978 48.0
TH1_k127_6158009_0 Putative peptidoglycan binding domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007633 263.0
TH1_k127_6158009_1 NUDIX domain - - - 0.00000000000000000000000000000000000000000001698 166.0
TH1_k127_6158009_2 PFAM Cytochrome C - - - 0.00000000000000000000000000000000000000005353 158.0
TH1_k127_6169444_0 B12 binding domain - - - 4.027e-300 924.0
TH1_k127_6169444_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.174e-289 892.0
TH1_k127_6169444_2 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000007723 212.0
TH1_k127_6169444_3 Haem-degrading - - - 0.00000000000000000000000000000000000000000000002105 174.0
TH1_k127_6169444_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000002137 149.0
TH1_k127_6169444_5 PFAM Plasmid stabilisation system - - - 0.00000001144 58.0
TH1_k127_6189878_0 DNA RNA helicase - - - 0.0 1373.0
TH1_k127_6189878_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.966e-238 739.0
TH1_k127_6189878_2 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 2.07e-214 668.0
TH1_k127_6189878_3 pfam mofrl K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000156 235.0
TH1_k127_6216597_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.103e-226 707.0
TH1_k127_6216597_1 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000000000000000000000000000000000000000000002419 220.0
TH1_k127_6216597_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000002679 220.0
TH1_k127_6216597_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000011 150.0
TH1_k127_6216597_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000006933 77.0
TH1_k127_6233002_0 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 331.0
TH1_k127_6233002_1 Protein of unknown function (DUF533) - - - 0.000000000000000000000000000000000000000366 156.0
TH1_k127_6233002_2 chaperone-mediated protein folding - - - 0.000000000004321 70.0
TH1_k127_6233002_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000002801 62.0
TH1_k127_6242885_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1105.0
TH1_k127_6242885_1 Protein of unknown function (DUF2380) - - - 0.000002057 49.0
TH1_k127_6244722_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1628.0
TH1_k127_6244722_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 592.0
TH1_k127_6244722_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 435.0
TH1_k127_6244722_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 388.0
TH1_k127_6244722_4 PFAM Mitochondrial inner membrane translocase complex, subunit Tim44-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 336.0
TH1_k127_6244722_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000666 63.0
TH1_k127_6263322_0 homoserine dehydrogenase K00003 - 1.1.1.3 3.83e-223 696.0
TH1_k127_6263322_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 549.0
TH1_k127_6276334_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 583.0
TH1_k127_6276334_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 492.0
TH1_k127_6276334_2 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 434.0
TH1_k127_6276928_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.696e-223 694.0
TH1_k127_6276928_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 507.0
TH1_k127_6276928_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000001109 214.0
TH1_k127_6304815_0 Participates in both transcription termination and antitermination K02600 - - 1.281e-229 720.0
TH1_k127_6304815_1 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000005932 179.0
TH1_k127_6304815_2 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000001071 128.0
TH1_k127_6304815_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000001162 72.0
TH1_k127_6304815_4 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000001161 66.0
TH1_k127_6304815_7 Transposase IS200 like K07491 - - 0.0002564 48.0
TH1_k127_6315914_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 512.0
TH1_k127_6315914_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000008401 246.0
TH1_k127_6315914_2 Predicted membrane protein (DUF2231) - - - 0.0009153 44.0
TH1_k127_6322526_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1296.0
TH1_k127_6322526_1 MreB/Mbl protein - - - 1.254e-273 851.0
TH1_k127_6322526_10 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.000000000000000000004361 93.0
TH1_k127_6322526_11 - - - - 0.0000000000000000002331 89.0
TH1_k127_6322526_13 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000001438 50.0
TH1_k127_6322526_14 PFAM Restriction endonuclease, type I, R subunit Type III, Res subunit K01156 - 3.1.21.5 0.00001434 48.0
TH1_k127_6322526_2 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 594.0
TH1_k127_6322526_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 602.0
TH1_k127_6322526_4 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 441.0
TH1_k127_6322526_5 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 328.0
TH1_k127_6322526_6 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 299.0
TH1_k127_6322526_7 GrpE K03687 - - 0.00000000000000000000000000000000000000000000000000000000005104 211.0
TH1_k127_6322526_8 response to abiotic stimulus - - - 0.000000000000000000000003106 103.0
TH1_k127_6322526_9 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000343 106.0
TH1_k127_6325285_0 PFAM Transposase IS66 family K07484 - - 7.702e-311 956.0
TH1_k127_6325285_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 327.0
TH1_k127_6325285_2 esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000001834 232.0
TH1_k127_6325285_3 PFAM IS66 Orf2 like protein - - - 0.00000000000000000000000000000000000000000000000000000000002994 208.0
TH1_k127_6325285_4 TraB family - - - 0.00000000000000000000000000000000000000000000004123 172.0
TH1_k127_6325285_5 transposase activity - - - 0.0000000000000000000000000000000000000005853 149.0
TH1_k127_6332677_0 TonB-dependent Receptor Plug - - - 1.552e-313 977.0
TH1_k127_6332677_1 PFAM Regulator of K conductance, N-terminal K10716 - - 2.011e-194 625.0
TH1_k127_6332677_10 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000000000000000000000000001728 231.0
TH1_k127_6332677_2 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 459.0
TH1_k127_6332677_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 360.0
TH1_k127_6332677_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 348.0
TH1_k127_6332677_5 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 296.0
TH1_k127_6332677_6 PFAM Regulator of K conductance, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001182 275.0
TH1_k127_6332677_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
TH1_k127_6332677_8 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005684 267.0
TH1_k127_6332677_9 YGGT family K02221 - - 0.00000000000000000000000000000000000000000000000000000000000000000001693 242.0
TH1_k127_6335047_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1982.0
TH1_k127_6335047_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 5.281e-304 947.0
TH1_k127_6335047_10 Protein of unknown function (DUF2970) - - - 0.00000001415 57.0
TH1_k127_6335047_2 Vitamin K-dependent gamma-carboxylase - - - 2.292e-254 799.0
TH1_k127_6335047_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 8.208e-241 754.0
TH1_k127_6335047_4 COG2206 HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 460.0
TH1_k127_6335047_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 423.0
TH1_k127_6335047_6 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000002689 182.0
TH1_k127_6335047_7 - - - - 0.00000000000000000000003038 104.0
TH1_k127_6335047_8 - - - - 0.0000000000000000058 89.0
TH1_k127_6349437_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 430.0
TH1_k127_6349437_1 RimK-like ATP-grasp domain K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 301.0
TH1_k127_6351229_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - - 0.0 1215.0
TH1_k127_6351229_1 Belongs to the peptidase S16 family - - - 0.0 1076.0
TH1_k127_6351229_2 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 597.0
TH1_k127_6351229_3 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 336.0
TH1_k127_6351229_4 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000153 208.0
TH1_k127_6351229_5 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000148 195.0
TH1_k127_6351229_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000003583 168.0
TH1_k127_6356253_0 Pyridoxal-phosphate dependent enzyme K01505 - 3.5.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 364.0
TH1_k127_6356253_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
TH1_k127_6356253_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003388 245.0
TH1_k127_6356253_3 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000006343 76.0
TH1_k127_6379525_0 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 283.0
TH1_k127_6379525_1 Belongs to the DnaA family. HdA subfamily K10763 - - 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
TH1_k127_6379525_2 arsenate reductase K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000238 175.0
TH1_k127_6379525_3 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000003211 106.0
TH1_k127_6385230_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1320.0
TH1_k127_6385230_1 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 1.713e-256 801.0
TH1_k127_6385230_10 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.00000009561 53.0
TH1_k127_6385230_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 585.0
TH1_k127_6385230_3 membrane-bound lytic murein transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 521.0
TH1_k127_6385230_4 glutamate decarboxylase activity K01590 - 4.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 476.0
TH1_k127_6385230_5 Sodium:neurotransmitter symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002875 252.0
TH1_k127_6385230_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
TH1_k127_6385230_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000001212 233.0
TH1_k127_6385230_8 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.00000000000000000268 90.0
TH1_k127_6385230_9 PFAM amino acid-binding ACT domain protein - - - 0.00000000006352 68.0
TH1_k127_6391733_0 ABC transporter transmembrane region K06148 - - 8.822e-235 736.0
TH1_k127_6391733_1 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000247 127.0
TH1_k127_6423066_0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 496.0
TH1_k127_6423066_1 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 486.0
TH1_k127_6423066_2 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000002324 215.0
TH1_k127_6423066_3 membrane - - - 0.000000000000000000000000000000000000000000000000001913 187.0
TH1_k127_6423066_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000007706 157.0
TH1_k127_6426648_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1039.0
TH1_k127_6426648_1 Ion channel - - - 0.0000000000000000000000000000000000003359 149.0
TH1_k127_6446199_0 DEAD DEAH box K03724 - - 0.0 2265.0
TH1_k127_6446199_1 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000002603 205.0
TH1_k127_6450894_0 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 538.0
TH1_k127_6450894_1 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 393.0
TH1_k127_6450894_2 Histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 345.0
TH1_k127_6450894_3 response regulator K15012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 301.0
TH1_k127_6480856_0 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 368.0
TH1_k127_6480856_1 FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 311.0
TH1_k127_6480856_2 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 312.0
TH1_k127_6480856_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0001093 52.0
TH1_k127_6484911_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 531.0
TH1_k127_6484911_1 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002976 281.0
TH1_k127_6484911_2 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000004867 249.0
TH1_k127_6493548_0 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 462.0
TH1_k127_6493548_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 327.0
TH1_k127_6493548_2 uracil-DNA K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000565 261.0
TH1_k127_6493548_3 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002127 257.0
TH1_k127_6508405_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 509.0
TH1_k127_6508405_1 PFAM Methylene-tetrahydromethanopterin dehydrogenase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 408.0
TH1_k127_6508405_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000001217 234.0
TH1_k127_6508405_3 pfam mofrl K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000003343 162.0
TH1_k127_6508405_4 PFAM Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.00000000000000000000001855 106.0
TH1_k127_6528043_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 517.0
TH1_k127_6528043_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000001494 172.0
TH1_k127_6528043_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000000009322 148.0
TH1_k127_6528043_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000005882 141.0
TH1_k127_6528043_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000004704 123.0
TH1_k127_6528043_5 Transcriptional regulator - - - 0.000000000003539 69.0
TH1_k127_6538290_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 550.0
TH1_k127_6550817_0 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 464.0
TH1_k127_6550817_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 448.0
TH1_k127_6550817_2 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.00000000000000000000000000000000000002814 144.0
TH1_k127_6550817_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000000002596 133.0
TH1_k127_6570691_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.595e-318 975.0
TH1_k127_6570691_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 602.0
TH1_k127_6570691_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 484.0
TH1_k127_6570691_3 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 337.0
TH1_k127_6570691_4 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002282 269.0
TH1_k127_6570691_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000009512 231.0
TH1_k127_6570691_6 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000008 204.0
TH1_k127_6570691_7 Protein of unknown function (DUF2909) - - - 0.000000000000000002056 89.0
TH1_k127_6571111_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 0.0 1392.0
TH1_k127_6571111_1 abc transporter atp-binding protein K02021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 396.0
TH1_k127_6571111_2 N-6 DNA methylase K03427 - 2.1.1.72 0.000000000000000000000000007475 109.0
TH1_k127_6585068_0 TIGRFAM dihydroxyacetone kinase, DhaK subunit K05878 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 548.0
TH1_k127_6585068_1 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 282.0
TH1_k127_6585068_2 TIGRFAM Dihydroxyacetone kinase K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000000000006526 177.0
TH1_k127_6587580_0 PFAM Polyphosphate kinase 2 - - - 1.314e-214 676.0
TH1_k127_6587580_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 486.0
TH1_k127_6587580_10 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000005653 137.0
TH1_k127_6587580_11 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000004056 131.0
TH1_k127_6587580_12 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000002062 126.0
TH1_k127_6587580_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 364.0
TH1_k127_6587580_3 C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 362.0
TH1_k127_6587580_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 298.0
TH1_k127_6587580_5 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008201 266.0
TH1_k127_6587580_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005186 259.0
TH1_k127_6587580_7 TIGRFAM SUF system FeS cluster assembly, Rtf2-type regulator - - - 0.0000000000000000000000000000000000000000000000000000000001215 206.0
TH1_k127_6587580_8 YCII-related domain K09780 - - 0.00000000000000000000000000000000000000009654 152.0
TH1_k127_6587580_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000001905 155.0
TH1_k127_6606219_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 502.0
TH1_k127_6606219_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002884 270.0
TH1_k127_6606219_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000267 209.0
TH1_k127_6615875_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 504.0
TH1_k127_6615875_1 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004457 281.0
TH1_k127_6631373_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 7.175e-293 905.0
TH1_k127_6631373_1 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.527e-291 902.0
TH1_k127_6631373_2 Ftsk_gamma K03466 - - 1.413e-243 761.0
TH1_k127_6631373_3 COG2206 HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 323.0
TH1_k127_6631373_4 - - - - 0.000000000000000000000000001361 115.0
TH1_k127_6635017_0 PFAM Aminoacyl-tRNA synthetase, class II (G H P S), conserved region K01892 - 6.1.1.21 9.172e-201 632.0
TH1_k127_6635017_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 556.0
TH1_k127_6635017_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 462.0
TH1_k127_6635017_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000005851 242.0
TH1_k127_6635017_4 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002573 241.0
TH1_k127_6635017_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000001981 229.0
TH1_k127_6635017_6 Pilus biogenesis K02656 - - 0.000000000000000000000000000000000000000000000000000003741 199.0
TH1_k127_6650336_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.929e-277 856.0
TH1_k127_6650336_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000004212 220.0
TH1_k127_6650336_2 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000002985 158.0
TH1_k127_6650336_3 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000001207 133.0
TH1_k127_6650336_4 - - - - 0.00000000000000009939 84.0
TH1_k127_6659938_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.229e-228 715.0
TH1_k127_6659938_1 Zeta toxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 598.0
TH1_k127_6661066_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.579e-230 718.0
TH1_k127_6661066_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 2.033e-198 623.0
TH1_k127_6661066_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 537.0
TH1_k127_6661066_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000008397 205.0
TH1_k127_6675607_0 Belongs to the heat shock protein 70 family - - - 0.0 1065.0
TH1_k127_6685887_0 Cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
TH1_k127_6685887_1 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000127 167.0
TH1_k127_6689609_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1252.0
TH1_k127_6689609_1 Type III K01156 - 3.1.21.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 314.0
TH1_k127_6689609_2 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000002275 230.0
TH1_k127_6689609_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000004165 51.0
TH1_k127_673521_0 Dynamin family - - - 2.534e-310 962.0
TH1_k127_673521_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 8.069e-254 789.0
TH1_k127_673521_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000002404 94.0
TH1_k127_673521_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.429e-246 767.0
TH1_k127_673521_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 578.0
TH1_k127_673521_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 541.0
TH1_k127_673521_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 504.0
TH1_k127_673521_6 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 374.0
TH1_k127_673521_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 314.0
TH1_k127_673521_8 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 302.0
TH1_k127_673521_9 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000001052 121.0
TH1_k127_6740007_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 582.0
TH1_k127_6740007_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 366.0
TH1_k127_6740007_2 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002967 245.0
TH1_k127_6740007_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 243.0
TH1_k127_6740007_4 deaminase zinc-binding - - - 0.000000000000000000000000000000000000005249 146.0
TH1_k127_6740007_5 Protein of unknown function, DUF393 - - - 0.0000000000000001509 80.0
TH1_k127_6771470_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 482.0
TH1_k127_6771470_1 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000001538 239.0
TH1_k127_6824680_0 PFAM Carbohydrate purine kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 430.0
TH1_k127_6824680_1 TIGRFAM HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003344 268.0
TH1_k127_6824680_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007208 253.0
TH1_k127_6824680_3 SMART Glycosyl hydrolase, family 13, subfamily, catalytic region K05341 - 2.4.1.4 0.000000000000000000000000000000000000000000000000000000002958 200.0
TH1_k127_683903_0 Cytochrome c554 and c-prime - - - 1.641e-306 958.0
TH1_k127_683903_1 PFAM Carbohydrate-selective porin OprB K07267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 361.0
TH1_k127_6855993_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 396.0
TH1_k127_6855993_1 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000288 264.0
TH1_k127_6855993_2 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000002363 139.0
TH1_k127_6870435_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.085e-208 658.0
TH1_k127_6870435_1 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000000000000000000001393 170.0
TH1_k127_6870435_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000003264 160.0
TH1_k127_6906025_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1398.0
TH1_k127_6906025_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000008366 124.0
TH1_k127_6909002_0 TIGRFAM Signal transduction histidine kinase, phosphate regulon sensor PhoR K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 522.0
TH1_k127_6909002_1 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 382.0
TH1_k127_6909002_2 Ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000259 273.0
TH1_k127_6909002_3 Belongs to the DnaA family. HdA subfamily K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000001198 225.0
TH1_k127_6909002_4 Maf-like protein - - - 0.0000000000000000000000000000000000000000000000000002852 190.0
TH1_k127_6909285_0 Type II/IV secretion system protein K02670 - - 1.218e-196 618.0
TH1_k127_6909285_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 329.0
TH1_k127_6909285_2 PFAM Binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000003045 215.0
TH1_k127_6909285_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000005824 94.0
TH1_k127_6909285_5 Protein of unknown function (DUF1640) - - - 0.0004981 44.0
TH1_k127_692386_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 534.0
TH1_k127_692386_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 531.0
TH1_k127_692386_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 491.0
TH1_k127_692386_3 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 432.0
TH1_k127_692386_4 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000004323 205.0
TH1_k127_692386_5 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000003604 141.0
TH1_k127_692386_6 PFAM Integrase core domain - - - 0.000000000000000000001534 97.0
TH1_k127_6925770_0 PFAM DNA mismatch repair protein MutS, C-terminal - - - 1.476e-225 710.0
TH1_k127_6925770_1 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 299.0
TH1_k127_6925770_2 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002144 274.0
TH1_k127_6925770_3 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000002578 99.0
TH1_k127_6925770_4 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000003777 75.0
TH1_k127_6954357_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.246e-221 702.0
TH1_k127_6954357_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 581.0
TH1_k127_6954357_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 546.0
TH1_k127_6954357_3 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 527.0
TH1_k127_6954357_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 443.0
TH1_k127_6954357_5 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 412.0
TH1_k127_6954357_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 354.0
TH1_k127_6954357_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000001155 159.0
TH1_k127_6960920_0 SMART HTH transcriptional regulator, Crp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 377.0
TH1_k127_6960920_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 342.0
TH1_k127_6960920_3 CsbD-like - - - 0.00000000000000000003041 93.0
TH1_k127_6960920_4 - - - - 0.000000000000001447 81.0
TH1_k127_6960920_5 Protein of unknown function (DUF3096) - - - 0.000000000000002106 76.0
TH1_k127_6960920_6 - - - - 0.000000000000005108 79.0
TH1_k127_6986496_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.713e-199 630.0
TH1_k127_6986496_1 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 578.0
TH1_k127_6986496_2 Belongs to the CinA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 451.0
TH1_k127_6986496_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 443.0
TH1_k127_6986496_4 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 390.0
TH1_k127_6986496_5 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 359.0
TH1_k127_6986496_6 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 360.0
TH1_k127_6986496_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 351.0
TH1_k127_6986496_8 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003299 228.0
TH1_k127_6986496_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000004175 170.0
TH1_k127_7006293_0 MacB-like periplasmic core domain K02004 - - 1.998e-245 783.0
TH1_k127_7006293_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.143e-235 743.0
TH1_k127_7006293_2 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 415.0
TH1_k127_7006293_3 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 288.0
TH1_k127_7006293_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004885 277.0
TH1_k127_7006293_5 PFAM Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001554 274.0
TH1_k127_7006293_6 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001439 273.0
TH1_k127_7006293_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004432 238.0
TH1_k127_70081_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 593.0
TH1_k127_70081_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 571.0
TH1_k127_70081_2 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 323.0
TH1_k127_70081_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000001675 113.0
TH1_k127_70081_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.0000000000000000000001803 97.0
TH1_k127_707843_0 Adenylosuccinate lyase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 520.0
TH1_k127_707843_1 Argininosuccinate lyase C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 496.0
TH1_k127_707843_2 phosphosulfolactate synthase activity K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 417.0
TH1_k127_707843_3 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 406.0
TH1_k127_707843_4 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 342.0
TH1_k127_707843_5 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit - - - 0.000000000000000000000000000000000000000004905 157.0
TH1_k127_707843_6 oxidoreductase - - - 0.000000000000000000000000000000002284 133.0
TH1_k127_7179750_0 PFAM Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 479.0
TH1_k127_7179750_1 membrane - - - 0.0000000000000000000000000000000000000000000000000009515 192.0
TH1_k127_7179750_2 - - - - 0.0000000000000000000000000000000002691 140.0
TH1_k127_7179750_3 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000001112 122.0
TH1_k127_7179979_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 419.0
TH1_k127_7179979_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 315.0
TH1_k127_7179979_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000008283 135.0
TH1_k127_7188998_0 PFAM Bacterial extracellular solute-binding - - - 5.768e-268 834.0
TH1_k127_7188998_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 314.0
TH1_k127_7188998_2 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000009514 101.0
TH1_k127_7188998_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000005682 48.0
TH1_k127_7223352_0 Phosphoketolase K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 334.0
TH1_k127_7223352_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 306.0
TH1_k127_7223352_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000007677 162.0
TH1_k127_7223352_3 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000001573 111.0
TH1_k127_7223352_4 ATP synthase alpha/beta family, beta-barrel domain K02118 - - 0.000000000000000000006597 93.0
TH1_k127_7282853_0 Multicopper oxidase - - - 1.634e-224 707.0
TH1_k127_7282853_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 300.0
TH1_k127_7282853_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007473 276.0
TH1_k127_7289356_0 alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 7.815e-225 732.0
TH1_k127_7289356_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 543.0
TH1_k127_7289356_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 363.0
TH1_k127_7289356_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000006419 229.0
TH1_k127_7289356_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000004754 213.0
TH1_k127_7310339_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 3.454e-232 733.0
TH1_k127_7310339_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 556.0
TH1_k127_7310339_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 428.0
TH1_k127_7310339_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 375.0
TH1_k127_7310339_4 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006492 245.0
TH1_k127_7310339_5 DNA helicase K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000201 171.0
TH1_k127_7310339_6 - - - - 0.0000000003092 62.0
TH1_k127_7310339_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000003413 61.0
TH1_k127_7310339_8 - - - - 0.000000007581 59.0
TH1_k127_7330814_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 534.0
TH1_k127_7330814_1 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 535.0
TH1_k127_7330814_2 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 331.0
TH1_k127_7340552_0 Major Facilitator Superfamily - - - 4.24e-272 842.0
TH1_k127_7340552_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 2.225e-213 667.0
TH1_k127_7340552_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 394.0
TH1_k127_7340552_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 367.0
TH1_k127_7340552_4 PFAM N-acetylmuramoyl-L-alanine amidase K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001552 272.0
TH1_k127_7340552_5 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001178 250.0
TH1_k127_7340552_6 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
TH1_k127_7340552_7 Iron-sulfur cluster insertion protein ErpA K15724 - - 0.000000000000000000000000000000000000000000000000000000000002165 209.0
TH1_k127_7340552_8 Major Facilitator Superfamily - - - 0.0000006255 53.0
TH1_k127_7340552_9 CMP dCMP deaminase, zinc-binding K01485 - 3.5.4.1 0.00001261 49.0
TH1_k127_7351643_0 Glycosyl hydrolase family 57 - - - 5.966e-312 970.0
TH1_k127_7351643_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.33e-288 896.0
TH1_k127_7351643_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005247 252.0
TH1_k127_7351643_11 ATP synthase, subunit K02124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008597 243.0
TH1_k127_7351643_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
TH1_k127_7351643_13 subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000001455 195.0
TH1_k127_7351643_14 - - - - 0.00000000000000000000000000000000000000000000001077 176.0
TH1_k127_7351643_15 DNA replication, synthesis of RNA primer K04066 - - 0.00000000000000000002333 96.0
TH1_k127_7351643_16 - - - - 0.00000000000000002791 82.0
TH1_k127_7351643_17 PFAM FAD dependent oxidoreductase - - - 0.00000000004067 64.0
TH1_k127_7351643_2 Phosphate transporter K03306 - - 2.751e-197 619.0
TH1_k127_7351643_3 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 614.0
TH1_k127_7351643_4 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 542.0
TH1_k127_7351643_5 TIGRFAM formylmethanofuran dehydrogenase subunit C K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 400.0
TH1_k127_7351643_6 Mut7-C ubiquitin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 372.0
TH1_k127_7351643_7 Pit accessory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 332.0
TH1_k127_7351643_8 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 293.0
TH1_k127_7351643_9 TIGRFAM Formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001523 276.0
TH1_k127_7356403_0 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 582.0
TH1_k127_7356403_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 452.0
TH1_k127_7356403_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007987 257.0
TH1_k127_7363114_0 haloacid dehalogenase-like hydrolase - - - 0.0 1092.0
TH1_k127_7363114_1 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 322.0
TH1_k127_7363114_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009376 280.0
TH1_k127_7363114_3 Sodium/hydrogen exchanger family - - - 0.00000000000002418 73.0
TH1_k127_74057_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 484.0
TH1_k127_74057_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 406.0
TH1_k127_74057_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 367.0
TH1_k127_74057_3 PFAM NADH ubiquinone K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 346.0
TH1_k127_74057_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000001338 181.0
TH1_k127_740775_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
TH1_k127_740775_1 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000003185 205.0
TH1_k127_740775_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000002272 175.0
TH1_k127_740775_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000001202 118.0
TH1_k127_740775_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000818 119.0
TH1_k127_7410092_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2280.0
TH1_k127_7410092_1 4Fe-4S dicluster domain K16965,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 4.253e-290 897.0
TH1_k127_7410092_2 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 363.0
TH1_k127_7410092_3 Nitrate reductase K00373 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008263 261.0
TH1_k127_7410092_4 - - - - 0.000000000001977 67.0
TH1_k127_7410092_5 Alginate export - - - 0.000009839 52.0
TH1_k127_7430048_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 331.0
TH1_k127_7430048_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 298.0
TH1_k127_7430048_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000525 70.0
TH1_k127_7447145_0 sulfate transport system, permease K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
TH1_k127_7447145_1 ABC transporter permease protein K02047 - - 0.00000000000000000000000000000000000000000000000000000000239 203.0
TH1_k127_7448379_0 Protein export membrane protein K03296,K18138 - - 1.677e-224 705.0
TH1_k127_7448379_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 441.0
TH1_k127_7448379_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 420.0
TH1_k127_7448379_3 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000005441 264.0
TH1_k127_7448379_4 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000142 258.0
TH1_k127_7457012_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 445.0
TH1_k127_7457012_1 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 316.0
TH1_k127_7457012_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000001269 241.0
TH1_k127_7457012_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000233 228.0
TH1_k127_7457012_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000215 224.0
TH1_k127_7457012_5 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000000000001665 214.0
TH1_k127_7464424_0 ABC transporter K15738 - - 6.98e-220 699.0
TH1_k127_7464424_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 318.0
TH1_k127_7464424_2 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 291.0
TH1_k127_7464424_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
TH1_k127_7464424_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000003466 96.0
TH1_k127_7464424_5 PFAM Metal-dependent phosphohydrolase, HD region, subdomain K08722 - 3.1.3.89 0.0008684 44.0
TH1_k127_7469186_0 Protein of unknown function - - - 1.778e-270 877.0
TH1_k127_7469186_1 ribonuclease, Rne Rng family K08301 - - 5.998e-261 809.0
TH1_k127_7469186_2 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 456.0
TH1_k127_7469186_3 Oxidoreductase NAD-binding domain K00523,K21832 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 386.0
TH1_k127_7469186_4 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000004838 129.0
TH1_k127_7472127_0 Sucrose phosphate synthase, sucrose phosphatase-like K00696 - 2.4.1.14 0.0 1084.0
TH1_k127_7472127_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 298.0
TH1_k127_7472127_2 TIGRFAM HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000003371 141.0
TH1_k127_7491345_0 helicase Cas3 K07012 - - 0.0 1102.0
TH1_k127_7491345_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.082e-301 927.0
TH1_k127_7491345_10 TIGRFAM Addiction module toxin, RelE StbE - - - 0.00000000000000000000000000000000000000001084 154.0
TH1_k127_7491345_11 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000000000000003181 144.0
TH1_k127_7491345_12 ATP synthase I chain K02116 - - 0.00000000000000000000000000000004829 128.0
TH1_k127_7491345_13 TIGRFAM CRISPR-associated protein, Cse1 family - - - 0.000000000000000000006852 99.0
TH1_k127_7491345_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 465.0
TH1_k127_7491345_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 452.0
TH1_k127_7491345_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 443.0
TH1_k127_7491345_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002994 280.0
TH1_k127_7491345_6 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005524 273.0
TH1_k127_7491345_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000000004602 220.0
TH1_k127_7491345_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000001963 201.0
TH1_k127_7491345_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000000000002062 165.0
TH1_k127_7492199_0 PFAM Major facilitator superfamily MFS-1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 360.0
TH1_k127_7492199_1 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 358.0
TH1_k127_7492199_2 Glutathione S-transferase, N-terminal domain K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 356.0
TH1_k127_7493326_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.458e-231 733.0
TH1_k127_7493326_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 406.0
TH1_k127_7493326_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 385.0
TH1_k127_7493326_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000004183 182.0
TH1_k127_7493326_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000004072 125.0
TH1_k127_7493326_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000003287 99.0
TH1_k127_7591838_0 P-type ATPase K17686 - 3.6.3.54 1.123e-310 974.0
TH1_k127_7591838_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
TH1_k127_7591838_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000002241 188.0
TH1_k127_7591838_3 - - - - 0.0000000000000000000000000000000000000000000000007128 185.0
TH1_k127_7591838_4 - - - - 0.000000000000000006745 89.0
TH1_k127_7591838_5 TIGRFAM ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system - - - 0.0000000000000008517 81.0
TH1_k127_7591838_6 - - - - 0.000000000000001036 78.0
TH1_k127_7591838_7 - - - - 0.00000000009253 65.0
TH1_k127_7594748_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1202.0
TH1_k127_7594748_1 Sulfatase - - - 2.696e-270 844.0
TH1_k127_7594748_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.947e-249 772.0
TH1_k127_7594748_3 Paraquat-inducible protein B - - - 4.461e-196 642.0
TH1_k127_7594748_4 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000007025 259.0
TH1_k127_7594748_5 paraquat-inducible protein A K03808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001026 218.0
TH1_k127_7594748_6 Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000004897 170.0
TH1_k127_7596108_0 PFAM sulfatase K01130 - 3.1.6.1 0.0 1080.0
TH1_k127_7596108_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 503.0
TH1_k127_7596108_2 Belongs to the peptidase S24 family K03503 - - 0.0000000000000000000000000000000000000000000000000000003246 196.0
TH1_k127_7596108_3 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000001019 146.0
TH1_k127_7596108_4 Glycine-zipper domain - - - 0.00000000000000000000000003885 112.0
TH1_k127_7608835_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 485.0
TH1_k127_7608835_1 glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 462.0
TH1_k127_7608835_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000002143 148.0
TH1_k127_7608835_3 Vibrio cholerae RfbT protein - - - 0.00000000004565 68.0
TH1_k127_7608835_4 Methyltransferase FkbM domain - - - 0.0002197 47.0
TH1_k127_7626895_0 PFAM lipopolysaccharide biosynthesis protein K16554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 428.0
TH1_k127_7626895_1 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.000000000000000000000000000001029 125.0
TH1_k127_7626895_2 - - - - 0.00000006584 62.0
TH1_k127_7627297_0 PFAM Sulfatase - - - 0.0 1158.0
TH1_k127_7627297_1 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 355.0
TH1_k127_7627297_2 Cytochrome c554 and c-prime - - - 0.0000000000000000009324 87.0
TH1_k127_7673404_0 CoA binding domain K09181 - - 0.0 1394.0
TH1_k127_7673404_1 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 514.0
TH1_k127_7673404_2 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009218 261.0
TH1_k127_767803_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 8.995e-257 800.0
TH1_k127_767803_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 289.0
TH1_k127_767803_2 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.000000001023 64.0
TH1_k127_7724405_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1250.0
TH1_k127_7724405_1 4Fe-4S dicluster domain K00124 - - 1.068e-307 953.0
TH1_k127_7724405_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 454.0
TH1_k127_7724405_3 TIGRFAM phenazine biosynthesis K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 432.0
TH1_k127_7724405_5 - - - - 0.00000000000000000000000000000000000672 138.0
TH1_k127_7724405_6 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000002147 131.0
TH1_k127_776243_0 Transport of potassium into the cell K03549 - - 5e-323 998.0
TH1_k127_776243_1 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000005864 164.0
TH1_k127_776243_2 - - - - 0.0000000000002477 76.0
TH1_k127_776243_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000004652 61.0
TH1_k127_7766808_0 Bacterial transglutaminase-like N-terminal - - - 0.0 1553.0
TH1_k127_7766808_1 Circularly permuted ATP-grasp type 2 - - - 0.0 1077.0
TH1_k127_7766808_2 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 362.0
TH1_k127_7766808_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate - - - 0.0000000000000000001393 89.0
TH1_k127_7786165_0 Belongs to the peptidase S16 family - - - 0.0 1067.0
TH1_k127_7786165_1 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 433.0
TH1_k127_7786165_2 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007489 241.0
TH1_k127_7786165_3 - - - - 0.0000000000000000000000000002708 119.0
TH1_k127_7786165_4 CYTH K01768 - 4.6.1.1 0.0000000000000000000000003352 106.0
TH1_k127_7786165_5 - - - - 0.0000000000000004233 82.0
TH1_k127_7786165_6 - - - - 0.0000000000000004524 85.0
TH1_k127_779110_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.211e-283 876.0
TH1_k127_779110_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 426.0
TH1_k127_779110_2 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 421.0
TH1_k127_779110_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 332.0
TH1_k127_779110_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 319.0
TH1_k127_779110_5 Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 297.0
TH1_k127_779110_6 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000005212 241.0
TH1_k127_779110_7 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.0000000000000000000000000000000000000000000000007186 176.0
TH1_k127_779110_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000002475 160.0
TH1_k127_780243_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 1.522e-264 823.0
TH1_k127_7818454_0 Aminotransferase class I and II - - - 4.863e-195 614.0
TH1_k127_7818454_1 Major Facilitator Superfamily K02429 - - 7.873e-195 615.0
TH1_k127_7818454_2 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 491.0
TH1_k127_7818454_3 Superoxide dismutase K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 293.0
TH1_k127_7818454_4 CDGSH-type zinc finger. Function unknown. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001793 287.0
TH1_k127_7818454_5 Domain of unknown function (DUF4160) - - - 0.0000000000000000000000000000000000000000000000008355 174.0
TH1_k127_7818454_6 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000002881 130.0
TH1_k127_7818454_7 phosphatase (DUF442) - - - 0.00000000000000000000000000000001714 130.0
TH1_k127_7818454_8 - - - - 0.0000000000000000000000001099 107.0
TH1_k127_7835812_0 Sulfate adenylyltransferase subunit 2 K00957 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004779,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 582.0
TH1_k127_7835812_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 563.0
TH1_k127_7852837_0 helix_turn_helix, mercury resistance K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 306.0
TH1_k127_7852837_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000007301 133.0
TH1_k127_7852837_2 - - - - 0.000000000003776 72.0
TH1_k127_7852837_3 PFAM Major Facilitator Superfamily - - - 0.0000001217 55.0
TH1_k127_7853242_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 613.0
TH1_k127_7853242_1 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000002202 243.0
TH1_k127_7853242_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000003149 67.0
TH1_k127_788102_0 GMC oxidoreductase - - - 2.001e-264 822.0
TH1_k127_788102_1 ABC transporter K02471 - - 3.745e-233 734.0
TH1_k127_788102_2 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000298 216.0
TH1_k127_788102_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000001422 54.0
TH1_k127_7895531_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 439.0
TH1_k127_7895531_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 392.0
TH1_k127_7895531_2 - - - - 0.00000000000000000006045 94.0
TH1_k127_7895531_3 - - - - 0.00000000000005657 79.0
TH1_k127_7916480_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 460.0
TH1_k127_7916480_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000002001 235.0
TH1_k127_7916480_2 PFAM Class II aldolase - - - 0.000000000000000000000000000000000000000000000000000000000001161 217.0
TH1_k127_7932708_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 5.071e-289 908.0
TH1_k127_7932708_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 344.0
TH1_k127_7956919_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 3.482e-229 718.0
TH1_k127_7980574_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 544.0
TH1_k127_7980574_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 425.0
TH1_k127_7980574_2 Histidine kinase - - - 0.000000000000000000000000000000008974 134.0
TH1_k127_7980574_3 ATPase, AAA K07478 - - 0.000000000000000003286 84.0
TH1_k127_8014502_0 PFAM Bacterial sugar transferase K03606 - - 2.914e-279 864.0
TH1_k127_8014502_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 346.0
TH1_k127_8014502_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 325.0
TH1_k127_8014502_3 polysaccharide export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000001533 223.0
TH1_k127_8014502_4 Mov34 MPN PAD-1 - - - 0.00000000000000000000000000000000000000000000005944 172.0
TH1_k127_8014502_5 peptidase - - - 0.000000000000000000000000000000000000002525 152.0
TH1_k127_8024846_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.878e-255 793.0
TH1_k127_8024846_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 494.0
TH1_k127_8051312_0 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 435.0
TH1_k127_8051312_1 phosphoglycolate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 332.0
TH1_k127_8051312_2 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000021 225.0
TH1_k127_8051312_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000000000001152 176.0
TH1_k127_8051312_4 TIGRFAM Hydrogenase expression formation protein, HupF HypC K04653 - - 0.00000000000000000000000000003174 118.0
TH1_k127_8053566_0 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 510.0
TH1_k127_8053566_1 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005814 272.0
TH1_k127_8053566_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000005432 90.0
TH1_k127_8068284_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.05e-238 751.0
TH1_k127_8068284_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 311.0
TH1_k127_8068284_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000002309 149.0
TH1_k127_8078765_0 G-rich domain on putative tyrosine kinase K16554,K16692 - - 0.0000000000000000000000000000000000000000000000000000000000000009285 220.0
TH1_k127_8078765_1 PFAM glycoside hydrolase family 39 K21000 - - 0.0000000000000000000003179 112.0
TH1_k127_8078765_2 Hydrolase Family 16 - - - 0.0000000000000001263 86.0
TH1_k127_8082439_0 ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 484.0
TH1_k127_8082439_1 Sulfate permease and related transporters (MFS superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 446.0
TH1_k127_8082439_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 392.0
TH1_k127_8082439_3 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003327 265.0
TH1_k127_8109930_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 6.83e-238 739.0
TH1_k127_8109930_1 PFAM Type II secretion system protein E K02454 - - 4.764e-214 676.0
TH1_k127_8109930_2 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 478.0
TH1_k127_8109930_3 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 363.0
TH1_k127_8109930_4 type II secretion system K02455 - - 0.000000000000000000000000000000000000002323 152.0
TH1_k127_8109930_5 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000002911 114.0
TH1_k127_8109930_6 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000009225 57.0
TH1_k127_8111992_0 Type III K01156 - 3.1.21.5 0.0 1042.0
TH1_k127_8111992_1 DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000001238 221.0
TH1_k127_8111992_2 Adenine specific DNA methylase Mod K00571,K07316,K07319 - 2.1.1.72 0.000000000000000000000000000000000000000000000000001604 184.0
TH1_k127_8111992_3 Plasmid maintenance system antidote protein K21498 - - 0.000000000000000000000001522 103.0
TH1_k127_8111992_4 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.00000000000000000000003436 104.0
TH1_k127_8111992_5 - - - - 0.0000000000000003854 85.0
TH1_k127_8113250_0 Protein of unknown function (DUF3375) - - - 7.84e-251 780.0
TH1_k127_8113250_1 Domain of unknown function (DUF4194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 298.0
TH1_k127_8113250_2 Redoxin K02199 - - 0.00000000000000000000000000000000000000000000000000007895 190.0
TH1_k127_8113250_3 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.000000000000000000000000000000000000000000000248 183.0
TH1_k127_8113250_4 subunit of a heme lyase K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.000000000000000000000000000000000000002482 159.0
TH1_k127_8113250_5 Putative exonuclease SbcCD, C subunit - - - 0.0000000000000000005763 89.0
TH1_k127_8113250_6 protein homotetramerization - - - 0.00003922 47.0
TH1_k127_8120378_0 membrane-bound metal-dependent K07038 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0031668,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 413.0
TH1_k127_8120378_1 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 295.0
TH1_k127_8120378_2 Belongs to the peptidase S24 family K03503 - - 0.0000005513 51.0
TH1_k127_8146921_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0 1040.0
TH1_k127_8156457_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 3.002e-217 682.0
TH1_k127_8156457_1 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 565.0
TH1_k127_8156457_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 504.0
TH1_k127_8173779_0 type IV, pilus assembly K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 487.0
TH1_k127_8173779_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000007458 210.0
TH1_k127_81802_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1265.0
TH1_k127_81802_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 4.24e-313 973.0
TH1_k127_81802_10 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000005975 264.0
TH1_k127_81802_11 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000000000000000001332 212.0
TH1_k127_81802_12 Transposase IS200 like K07491 - - 0.0000000000000000000000000000004274 123.0
TH1_k127_81802_13 Transposase IS200 like K07491 - - 0.00000000000000000001342 93.0
TH1_k127_81802_2 Response regulator receiver - - - 2.629e-221 692.0
TH1_k127_81802_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 584.0
TH1_k127_81802_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 524.0
TH1_k127_81802_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 450.0
TH1_k127_81802_6 PFAM DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 459.0
TH1_k127_81802_7 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 427.0
TH1_k127_81802_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 414.0
TH1_k127_81802_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 269.0
TH1_k127_8182398_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002747 271.0
TH1_k127_8182398_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000286 190.0
TH1_k127_8219538_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.304e-314 967.0
TH1_k127_8221042_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.389e-235 733.0
TH1_k127_8221042_1 Plant specific mitochondrial import receptor subunit TOM20 - - - 0.00000000000000000000000000000000000000000000000000003379 196.0
TH1_k127_8221042_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000136 146.0
TH1_k127_8221042_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000007926 79.0
TH1_k127_8249194_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 450.0
TH1_k127_8249194_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 396.0
TH1_k127_8249194_2 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000008014 113.0
TH1_k127_8249194_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000001813 111.0
TH1_k127_8249194_4 Domain of unknown function (DUF4124) - - - 0.00001744 53.0
TH1_k127_8261095_0 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 335.0
TH1_k127_8261095_1 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000000000000000000000000000000000001584 183.0
TH1_k127_8276530_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1080.0
TH1_k127_8276530_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 492.0
TH1_k127_8276530_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000001852 119.0
TH1_k127_8276530_3 Methyltransferase domain - - - 0.00000000000000000000000000003833 118.0
TH1_k127_8276530_4 SPTR Alr4702 protein - - - 0.0000000004153 63.0
TH1_k127_8276530_5 Resolvase - - - 0.000000008287 57.0
TH1_k127_8280328_0 PFAM alpha beta hydrolase K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 437.0
TH1_k127_8280328_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 293.0
TH1_k127_8280328_2 Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 295.0
TH1_k127_8347710_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 561.0
TH1_k127_8347710_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 413.0
TH1_k127_8347710_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 402.0
TH1_k127_8347710_3 PFAM Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 334.0
TH1_k127_8347710_4 - - - - 0.00000000000000000000000000000000000139 157.0
TH1_k127_8347710_5 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0005938 46.0
TH1_k127_8355916_0 esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 539.0
TH1_k127_8355916_1 Domain of unknown function (DUF4410) - - - 0.0000000000000000000000000000000000000000000000000000000000000004701 226.0
TH1_k127_8355916_2 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000006569 190.0
TH1_k127_8355916_3 - - - - 0.00000000000000000000000000000000000000000000001063 181.0
TH1_k127_8355916_4 - - - - 0.000000000000415 70.0
TH1_k127_8372067_0 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 523.0
TH1_k127_8372067_1 PFAM Glycosyl transferase, family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 439.0
TH1_k127_8372067_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 418.0
TH1_k127_8372067_3 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 446.0
TH1_k127_8372067_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 324.0
TH1_k127_8372067_5 Peptidyl-prolyl cis-trans isomerase K01802,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000008403 228.0
TH1_k127_8372067_6 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000000000000002837 152.0
TH1_k127_8372067_7 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000004841 140.0
TH1_k127_8372067_8 - - - - 0.00000000000000000000000000007657 118.0
TH1_k127_8372067_9 Transposase K07481 - - 0.00000397 49.0
TH1_k127_8424376_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 603.0
TH1_k127_8424376_1 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 491.0
TH1_k127_8424376_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 376.0
TH1_k127_8424376_3 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 358.0
TH1_k127_8424376_4 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 305.0
TH1_k127_8439652_0 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 335.0
TH1_k127_8439652_1 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 307.0
TH1_k127_8471913_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 345.0
TH1_k127_8471913_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000001875 118.0
TH1_k127_8475440_0 UvrD-like helicase C-terminal domain K03654 - 3.6.4.12 0.0 1294.0
TH1_k127_8488506_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 558.0
TH1_k127_8488506_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 347.0
TH1_k127_8488506_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000001186 53.0
TH1_k127_8510939_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006169 266.0
TH1_k127_8510939_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000003008 230.0
TH1_k127_8510939_2 PilZ domain - - - 0.0000000000002912 76.0
TH1_k127_8528496_0 PFAM Sulphate transporter - - - 1.773e-262 820.0
TH1_k127_8528496_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 320.0
TH1_k127_8566985_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1479.0
TH1_k127_8566985_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.95e-302 938.0
TH1_k127_8566985_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K14067 - 6.2.1.9 7.203e-209 653.0
TH1_k127_8566985_3 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 572.0
TH1_k127_8566985_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 521.0
TH1_k127_8566985_5 PFAM Radical SAM K19810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 435.0
TH1_k127_8566985_6 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 409.0
TH1_k127_8566985_7 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 342.0
TH1_k127_861917_0 Peptidase, M48 K06013 - 3.4.24.84 3.901e-196 618.0
TH1_k127_861917_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 377.0
TH1_k127_861917_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 301.0
TH1_k127_861917_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004799 270.0
TH1_k127_861917_4 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000001086 50.0
TH1_k127_8674436_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 0.0 1170.0
TH1_k127_8674436_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 9.027e-261 814.0
TH1_k127_8674436_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 559.0
TH1_k127_8674436_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 349.0
TH1_k127_8674436_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 261.0
TH1_k127_8674436_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000004304 175.0
TH1_k127_8691223_0 FtsX-like permease family K02004 - - 0.0 1093.0
TH1_k127_8691223_1 - - - - 0.0000000000000000000000000000000000000000000000000849 178.0
TH1_k127_8691223_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000002531 162.0
TH1_k127_8691223_3 - - - - 0.000000000000000000000000000000003953 130.0
TH1_k127_8716421_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 8.209e-243 758.0
TH1_k127_8716421_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 8.756e-201 635.0
TH1_k127_8716421_10 - - - - 0.00000000000000000000000000000000376 137.0
TH1_k127_8716421_11 Rubredoxin - - - 0.000000000000000000000003928 104.0
TH1_k127_8716421_2 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 541.0
TH1_k127_8716421_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 458.0
TH1_k127_8716421_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 413.0
TH1_k127_8716421_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 316.0
TH1_k127_8716421_6 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
TH1_k127_8716421_7 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000002059 172.0
TH1_k127_8716421_8 response to cobalt ion - - - 0.0000000000000000000000000000000000000000000009531 167.0
TH1_k127_8716421_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000001576 167.0
TH1_k127_8734830_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 526.0
TH1_k127_8734830_1 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 480.0
TH1_k127_8734830_2 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 379.0
TH1_k127_8734830_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 328.0
TH1_k127_8734830_4 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 319.0
TH1_k127_8734830_5 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003558 248.0
TH1_k127_8734830_6 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000000000000000000000000009656 134.0
TH1_k127_8734830_7 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000159 116.0
TH1_k127_8734830_8 Winged helix-turn-helix domain (DUF2582) - - - 0.00000000000000000001932 92.0
TH1_k127_8762193_0 PFAM Cytochrome d1 K19345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 595.0
TH1_k127_8762193_1 PFAM Cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 301.0
TH1_k127_8762193_2 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.000000000000000000000000000000004246 131.0
TH1_k127_8762193_3 PFAM Cytochrome C - - - 0.000000000000000000000000000000296 125.0
TH1_k127_8762193_4 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000001037 70.0
TH1_k127_8762193_5 - - - - 0.00000511 51.0
TH1_k127_8764366_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.221e-203 637.0
TH1_k127_8764366_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 394.0
TH1_k127_8764366_2 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 393.0
TH1_k127_8764366_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000009585 195.0
TH1_k127_8764366_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0003341 44.0
TH1_k127_8789377_0 Transglycosylase - - - 1.054e-246 782.0
TH1_k127_8789377_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 539.0
TH1_k127_8789377_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000007438 241.0
TH1_k127_8789377_3 - - - - 0.000000000000000000000000000000001319 135.0
TH1_k127_8819556_0 Belongs to the UPF0753 family K09822 - - 0.0 1225.0
TH1_k127_8819556_1 PFAM Sulfate transporter family - - - 2.327e-231 726.0
TH1_k127_8819556_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.446e-201 638.0
TH1_k127_8819556_3 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 614.0
TH1_k127_8819556_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 598.0
TH1_k127_8819556_5 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 580.0
TH1_k127_8819556_6 Glycosyl transferase family 8 - - - 0.000000000000000000000004276 104.0
TH1_k127_8819556_7 Glycosyl transferase family 8 - - - 0.00000000002488 66.0
TH1_k127_8853353_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000008106 211.0
TH1_k127_8853353_2 Cytochrome oxidase assembly K02259 - - 0.00000000000000000000000006093 110.0
TH1_k127_8882446_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.678e-228 712.0
TH1_k127_8882446_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 555.0
TH1_k127_8882446_2 Belongs to the RimK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 425.0
TH1_k127_8882446_3 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 348.0
TH1_k127_8882446_4 PFAM Formaldehyde-activating enzyme K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 298.0
TH1_k127_8882446_5 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000002164 225.0
TH1_k127_8882446_6 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0071704 3.5.4.27 0.000000000000000000000000000000001687 129.0
TH1_k127_8882446_7 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000007045 113.0
TH1_k127_8896787_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1349.0
TH1_k127_8896787_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1018.0
TH1_k127_8896787_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
TH1_k127_8896787_11 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000266 245.0
TH1_k127_8896787_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001788 242.0
TH1_k127_8896787_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000003779 232.0
TH1_k127_8896787_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000002203 222.0
TH1_k127_8896787_15 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000001132 218.0
TH1_k127_8896787_16 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000002025 217.0
TH1_k127_8896787_17 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000001825 206.0
TH1_k127_8896787_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000003087 203.0
TH1_k127_8896787_19 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000002465 201.0
TH1_k127_8896787_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.347e-242 753.0
TH1_k127_8896787_20 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000001552 178.0
TH1_k127_8896787_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000000000005564 168.0
TH1_k127_8896787_22 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000006293 162.0
TH1_k127_8896787_23 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000001199 161.0
TH1_k127_8896787_25 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000002639 146.0
TH1_k127_8896787_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000005989 147.0
TH1_k127_8896787_27 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000006532 114.0
TH1_k127_8896787_28 Ribosomal protein L30 K02907 - - 0.00000000000000000001027 94.0
TH1_k127_8896787_29 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000001593 83.0
TH1_k127_8896787_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.472e-241 758.0
TH1_k127_8896787_30 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002944 73.0
TH1_k127_8896787_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 7.219e-228 712.0
TH1_k127_8896787_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 529.0
TH1_k127_8896787_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 388.0
TH1_k127_8896787_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 354.0
TH1_k127_8896787_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 308.0
TH1_k127_8896787_9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 288.0
TH1_k127_8909900_0 PFAM Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 398.0
TH1_k127_8909900_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 351.0
TH1_k127_8909900_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000015 252.0
TH1_k127_8919666_0 BT1 family - - - 4.28e-249 781.0
TH1_k127_8919666_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 2.761e-207 651.0
TH1_k127_8919666_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 594.0
TH1_k127_8919666_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 552.0
TH1_k127_8919666_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 556.0
TH1_k127_8919666_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 396.0
TH1_k127_8919666_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007756 262.0
TH1_k127_8919666_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000001055 208.0
TH1_k127_8919666_8 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000000000000000002135 153.0
TH1_k127_8919666_9 HupE UreJ protein K03192 - - 0.00000000000000000000000000000000003219 141.0
TH1_k127_895032_0 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 381.0
TH1_k127_895032_1 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000005075 250.0
TH1_k127_895032_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000000000000000000000000000000005575 192.0
TH1_k127_895032_3 Transporter associated domain K03699 - - 0.00000000000000000003827 91.0
TH1_k127_895032_4 DDE superfamily endonuclease - - - 0.0000000000000000624 84.0
TH1_k127_895032_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000007448 61.0
TH1_k127_895032_6 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000001357 66.0
TH1_k127_8960807_0 2 iron, 2 sulfur cluster binding - - - 0.0 1726.0
TH1_k127_8964514_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 563.0
TH1_k127_8964514_1 Lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000003443 223.0
TH1_k127_8964514_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000001374 145.0
TH1_k127_8964514_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000002071 146.0
TH1_k127_8968438_0 Alpha amylase, catalytic domain - - - 0.0 1246.0
TH1_k127_8968438_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
TH1_k127_8968438_2 thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000001287 199.0
TH1_k127_8968531_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 546.0
TH1_k127_8968531_1 PFAM Uncharacterised protein family (UPF0150) - - - 0.0000000000003344 72.0
TH1_k127_8968531_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000003503 66.0
TH1_k127_8984822_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 366.0
TH1_k127_8985125_0 PFAM PhoH-like protein K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 589.0
TH1_k127_8985125_1 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000002525 215.0
TH1_k127_8985125_2 ACT domain K03567 - - 0.0000000000000000000003014 99.0
TH1_k127_8985125_3 ACT domain K03567 - - 0.00000000000000002599 83.0
TH1_k127_9004517_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003824,GO:0004654,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.8 0.0 1004.0
TH1_k127_9004517_1 DNA polymerase - - - 0.00000000000000000000000000000002022 130.0
TH1_k127_900812_0 NMT1-like family K15576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 465.0
TH1_k127_900812_1 PFAM response regulator receiver K07183 - - 0.0000000000000000000000000000000000000000000000000000000002544 208.0
TH1_k127_900812_2 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000001141 192.0
TH1_k127_900812_3 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000000000000000000000006278 187.0
TH1_k127_900812_4 Peptidase C39 family K06992 - - 0.000000000000000000000000000001806 127.0
TH1_k127_9025827_0 - - - - 8.981e-305 937.0
TH1_k127_9025827_1 Sulfatase K01130 - 3.1.6.1 1.82e-286 886.0
TH1_k127_9025827_10 Small-conductance mechanosensitive channel K05802 - - 0.0000002405 54.0
TH1_k127_9025827_11 transmembrane transport K03442,K22044 - - 0.0005378 48.0
TH1_k127_9025827_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003241 286.0
TH1_k127_9025827_3 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000000000000000000000001102 235.0
TH1_k127_9025827_5 - - - - 0.0000000000000000000000000000000000000002919 151.0
TH1_k127_9025827_6 Ecotin K08276 - - 0.0000000000000000000000000000001552 129.0
TH1_k127_9025827_7 - - - - 0.000000000000000000000000000008252 120.0
TH1_k127_9025827_8 - - - - 0.0000000000000000000141 96.0
TH1_k127_9025827_9 mechanosensitive ion channel - - - 0.0000000000000000002698 89.0
TH1_k127_902970_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.036e-251 783.0
TH1_k127_902970_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 449.0
TH1_k127_902970_2 PFAM Glutathione S-transferase, N-terminal K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 332.0
TH1_k127_902970_3 Cytochrome C1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 333.0
TH1_k127_902970_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 322.0
TH1_k127_902970_5 Putative DNA-binding domain K09929 - - 0.000000000000000000000000000000000000000000000000000000000000000002872 237.0
TH1_k127_902970_6 PFAM Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000001353 194.0
TH1_k127_902970_7 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000002938 138.0
TH1_k127_902970_8 Domain of unknown function (DUF1820) - - - 0.000000000000000000000000000000009087 129.0
TH1_k127_902970_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000001375 61.0
TH1_k127_9052275_0 Polysaccharide biosynthesis protein - - - 2.465e-265 829.0
TH1_k127_9052275_1 HTH transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 440.0
TH1_k127_9052275_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 416.0
TH1_k127_9052275_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 364.0
TH1_k127_9052275_4 epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 307.0
TH1_k127_9052275_5 Glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 276.0
TH1_k127_9052275_6 Domain of Unknown Function with PDB structure (DUF3862) - - - 0.0000000000000000001776 91.0
TH1_k127_9069293_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1104.0
TH1_k127_9069293_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 1.117e-240 749.0
TH1_k127_9069293_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 2.235e-204 640.0
TH1_k127_9069293_3 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 569.0
TH1_k127_9069293_4 (Lipo)protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 323.0
TH1_k127_9069293_5 Copper resistance K07245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 307.0
TH1_k127_9069293_6 PFAM Toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001421 270.0
TH1_k127_9069293_7 TIGRFAM Hopanoid-associated phosphorylase K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000000000000004308 195.0
TH1_k127_9069293_8 CopC domain K07156 - - 0.0000000000000000000000000001433 120.0
TH1_k127_9069293_9 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0007427 42.0
TH1_k127_911885_0 Oxaloacetate decarboxylase, alpha subunit K01571 - 4.1.1.3 5.415e-267 835.0
TH1_k127_911885_1 decarboxylase, beta subunit K01572 - 4.1.1.3 1.333e-197 623.0
TH1_k127_911885_2 Histidine kinase K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 564.0
TH1_k127_911885_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 448.0
TH1_k127_911885_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008261 282.0
TH1_k127_911885_5 Lyase and sodium transporter K01573 - 4.1.1.3 0.000001164 53.0
TH1_k127_9131525_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 1.087e-270 839.0
TH1_k127_9131525_1 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 4.774e-233 732.0
TH1_k127_9131525_2 HI0933-like protein K10210 - 1.14.99.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 374.0
TH1_k127_9131525_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000248 177.0
TH1_k127_9134926_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 477.0
TH1_k127_9134926_1 - - - - 0.000000000000000000000000000000000000000272 155.0
TH1_k127_9159114_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1339.0
TH1_k127_9159114_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 454.0
TH1_k127_9185397_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0008150,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0042546,GO:0044085,GO:0071554,GO:0071840 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 444.0
TH1_k127_9185397_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 451.0
TH1_k127_9185397_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 409.0
TH1_k127_9185397_3 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 408.0
TH1_k127_9185397_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 342.0
TH1_k127_9185397_5 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001909 285.0
TH1_k127_9185397_6 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002809 271.0
TH1_k127_9185397_7 HIT domain - - - 0.00000000000000000000000000000000000000000000000000000000375 203.0
TH1_k127_9185397_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000011 164.0
TH1_k127_9185397_9 Dodecin K09165 - - 0.000000000000000000000000000001967 123.0
TH1_k127_9186299_0 TIGRFAM RNA helicase, ATP-dependent DEAH box, HrpA type K03578 - 3.6.4.13 0.0 1050.0
TH1_k127_9186299_1 esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 327.0
TH1_k127_9186299_2 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004587 222.0
TH1_k127_9186299_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000002562 138.0
TH1_k127_9186299_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000148 63.0
TH1_k127_9186299_5 PFAM DNA methylase N-4 N-6 K07316 - 2.1.1.72 0.0000122 48.0
TH1_k127_9195969_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1311.0
TH1_k127_9195969_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.533e-250 781.0
TH1_k127_9195969_10 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 359.0
TH1_k127_9195969_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 334.0
TH1_k127_9195969_12 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001567 272.0
TH1_k127_9195969_13 PFAM Cystathionine beta-synthase, core K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000008022 228.0
TH1_k127_9195969_14 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000007846 217.0
TH1_k127_9195969_15 Belongs to the UPF0149 family K09895 - - 0.00000000000000000000000000000000000000000000000008845 183.0
TH1_k127_9195969_16 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000004098 109.0
TH1_k127_9195969_17 - K09892 - - 0.00000000000000001431 85.0
TH1_k127_9195969_18 - - - - 0.0000005201 52.0
TH1_k127_9195969_2 Belongs to the peptidase M24B family K01262 - 3.4.11.9 2.175e-230 718.0
TH1_k127_9195969_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.095e-229 715.0
TH1_k127_9195969_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 605.0
TH1_k127_9195969_5 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 522.0
TH1_k127_9195969_6 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 506.0
TH1_k127_9195969_7 glucosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 459.0
TH1_k127_9195969_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 381.0
TH1_k127_9195969_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 370.0
TH1_k127_9201862_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 1.474e-304 979.0
TH1_k127_9201862_1 Surface antigen K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 573.0
TH1_k127_9201862_2 PFAM Isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 550.0
TH1_k127_9201862_3 PFAM Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 475.0
TH1_k127_9201862_4 alcohol dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 453.0
TH1_k127_9201862_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 334.0
TH1_k127_9201862_6 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000000000000000000001474 201.0
TH1_k127_9201862_7 - - - - 0.0000000000004617 76.0
TH1_k127_9201862_8 PFAM Methylene-tetrahydromethanopterin dehydrogenase, N-terminal - - - 0.000000000001163 68.0
TH1_k127_9217385_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1135.0
TH1_k127_9217385_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 304.0
TH1_k127_9217385_2 PFAM Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
TH1_k127_9217385_3 SMART Cold shock protein K03704 - - 0.0000000000000000000000000000001363 124.0
TH1_k127_9217385_4 membrane transporter protein K07090 - - 0.00004389 46.0
TH1_k127_9222035_0 Glycogen debranching enzyme - - - 0.0 1667.0
TH1_k127_9222035_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1206.0
TH1_k127_9222035_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.128e-292 913.0
TH1_k127_9222035_3 Alpha amylase, catalytic domain - - - 3.991e-275 851.0
TH1_k127_9222035_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 504.0
TH1_k127_9222035_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 435.0
TH1_k127_9222035_6 Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 340.0
TH1_k127_9222035_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006073 273.0
TH1_k127_9240284_0 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 586.0
TH1_k127_9240284_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 419.0
TH1_k127_9240284_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000008654 250.0
TH1_k127_9240284_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000008171 214.0
TH1_k127_9240284_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000008012 142.0
TH1_k127_9258218_0 PFAM Binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 315.0
TH1_k127_9258218_1 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 261.0
TH1_k127_9266894_0 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 332.0
TH1_k127_9266894_1 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 330.0
TH1_k127_9266894_2 pfam ammecr1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000004191 231.0
TH1_k127_9266894_3 PFAM Binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000003308 161.0
TH1_k127_9266894_4 - - - - 0.000000000000006922 82.0
TH1_k127_9266894_5 - - - - 0.000000000006376 71.0
TH1_k127_9275596_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1334.0
TH1_k127_9275596_1 Cation transporter/ATPase, N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 508.0
TH1_k127_9275596_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0004566 43.0
TH1_k127_9287332_0 PFAM Integrase catalytic - - - 2.427e-221 696.0
TH1_k127_9289485_0 PFAM ERCC4 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 333.0
TH1_k127_9289485_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000006644 112.0
TH1_k127_9289485_2 Forkhead associated domain - - - 0.0000000000000000001185 93.0
TH1_k127_9307345_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 548.0
TH1_k127_9307345_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000008596 172.0
TH1_k127_9320764_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 501.0
TH1_k127_9320764_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000691 236.0
TH1_k127_9320764_2 Group 1 truncated hemoglobin K06886 - - 0.00000000000000000000000000000000000000000000000000000001116 199.0
TH1_k127_9320764_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000314 192.0
TH1_k127_9320764_4 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000001442 177.0
TH1_k127_9320764_5 Alginate export - - - 0.00000000000000000000000000000000000001182 146.0
TH1_k127_937575_0 DHH family K07462 - - 4.747e-267 832.0
TH1_k127_937575_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 2.67e-208 653.0
TH1_k127_937575_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 434.0
TH1_k127_937575_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000009258 241.0
TH1_k127_937575_4 PFAM Bacterial extracellular solute-binding - - - 0.00000000000000000000000000000000000000000000000000000002234 203.0
TH1_k127_937575_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000001088 145.0
TH1_k127_937575_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000001959 136.0
TH1_k127_937575_7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000003218 114.0
TH1_k127_9384485_0 Nitrogen regulation K07712 - - 3.742e-201 633.0
TH1_k127_9384485_1 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 329.0
TH1_k127_9384485_2 PFAM HTH transcriptional regulator, MarR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003165 249.0
TH1_k127_939509_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 9.765e-285 891.0
TH1_k127_939509_1 GlutRNAGln amidotransferase subunit D K01424 - 3.5.1.1 0.000000000000000000000000005113 113.0
TH1_k127_9407075_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003273 280.0
TH1_k127_9407075_1 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000007019 218.0
TH1_k127_9407075_2 Protein of unknown function (DUF1249) K09920 - - 0.00000000000000000000000000000000000000000004469 164.0
TH1_k127_9407075_3 PilZ domain - - - 0.0000000000003743 73.0
TH1_k127_9407075_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000007188 60.0
TH1_k127_9419369_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 439.0
TH1_k127_9419369_1 PFAM NnrS K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000002709 234.0
TH1_k127_9432288_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1672.0
TH1_k127_9432288_1 alpha beta alpha domain I K01835 - 5.4.2.2 5.284e-280 867.0
TH1_k127_9432288_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000027 263.0
TH1_k127_9432288_11 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003376 243.0
TH1_k127_9432288_12 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002228 225.0
TH1_k127_9432288_13 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000005269 206.0
TH1_k127_9432288_14 PFAM Lipid A Biosynthesis N-terminal - - - 0.00000000000000000000000000000000000003866 147.0
TH1_k127_9432288_15 - - - - 0.0000000000000000000000000000000000000866 146.0
TH1_k127_9432288_16 Alanine-zipper, major outer membrane lipoprotein - - - 0.00000000000000000000134 96.0
TH1_k127_9432288_17 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000000000000002805 94.0
TH1_k127_9432288_18 PFAM Integrase core domain - - - 0.00000000000000001931 83.0
TH1_k127_9432288_2 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00124 - - 6.652e-276 854.0
TH1_k127_9432288_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 567.0
TH1_k127_9432288_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 464.0
TH1_k127_9432288_5 ZIP Zinc transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 385.0
TH1_k127_9432288_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 382.0
TH1_k127_9432288_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 361.0
TH1_k127_9432288_8 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 354.0
TH1_k127_9432288_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 309.0
TH1_k127_9464986_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 4.341e-212 665.0
TH1_k127_9464986_1 PFAM Multicopper oxidase, type K04753,K08100,K14588 - 1.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 479.0
TH1_k127_9464986_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 464.0
TH1_k127_9464986_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 328.0
TH1_k127_9464986_4 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 318.0
TH1_k127_9464986_6 Stress responsive A/B Barrel Domain - - - 0.0000000000000000000000000000000000000004907 153.0
TH1_k127_9464986_7 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000004803 89.0
TH1_k127_9586564_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1834.0
TH1_k127_9586564_1 Orotidine 5'-phosphate decarboxylase / HUMPS family K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 604.0
TH1_k127_9586564_2 RNA-binding protein homologous to eukaryotic snRNP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 518.0
TH1_k127_9586564_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 485.0
TH1_k127_9586564_4 Domain of unknown function (DUF1788) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
TH1_k127_9586564_5 Putative inner membrane protein (DUF1819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 244.0
TH1_k127_9586564_6 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000001414 152.0
TH1_k127_9599928_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.887e-230 715.0
TH1_k127_9599928_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000002788 164.0
TH1_k127_9610517_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 3.888e-255 790.0
TH1_k127_9610517_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 580.0
TH1_k127_9610517_10 - - - - 0.000000000001679 80.0
TH1_k127_9610517_2 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 390.0
TH1_k127_9610517_3 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 334.0
TH1_k127_9610517_4 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003357 275.0
TH1_k127_9610517_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000004624 237.0
TH1_k127_9610517_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000005582 196.0
TH1_k127_9610517_7 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000001609 166.0
TH1_k127_9610517_8 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000239 161.0
TH1_k127_9610517_9 Protein required for attachment to host cells - - - 0.0000000000005245 71.0
TH1_k127_9629938_0 Chromate transporter - - - 1.892e-234 730.0
TH1_k127_9629938_1 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 406.0
TH1_k127_9629938_2 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 258.0
TH1_k127_9637067_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 0.0 1148.0
TH1_k127_9637067_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 522.0
TH1_k127_9637067_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002574 282.0
TH1_k127_9637067_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000005952 197.0
TH1_k127_9637067_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000001895 153.0
TH1_k127_9637067_5 Membrane - - - 0.0000000000000000000000000000000000000002161 161.0
TH1_k127_9637067_6 - - - - 0.00000000000000000000000000000634 122.0
TH1_k127_9637067_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000001835 102.0
TH1_k127_9637067_8 - - - - 0.0001479 46.0
TH1_k127_96950_0 Carbon starvation protein CstA K06200 - - 0.0 1199.0
TH1_k127_96950_1 Cellulase (glycosyl hydrolase family 5) K01210 - 3.2.1.58 0.00000000000000000002897 91.0
TH1_k127_9697082_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 597.0
TH1_k127_9697082_1 RDD family - - - 0.000000000000000000000000000000000000000000000000000001876 195.0
TH1_k127_9697082_2 - - - - 0.00000000000002518 75.0
TH1_k127_9706367_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 560.0
TH1_k127_9706367_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 553.0
TH1_k127_9706367_10 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) - - - 0.000000000000006313 78.0
TH1_k127_9706367_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000003234 61.0
TH1_k127_9706367_2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 306.0
TH1_k127_9706367_3 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
TH1_k127_9706367_4 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 299.0
TH1_k127_9706367_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006887 269.0
TH1_k127_9706367_6 Ribose 5-phosphate isomerase K01808 GO:0003674,GO:0003824,GO:0004751,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008786,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019313,GO:0019314,GO:0019316,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046367,GO:0071704,GO:1901575 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000924 267.0
TH1_k127_9706367_7 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005239 267.0
TH1_k127_9706367_8 Rubredoxin - - - 0.000000000000000000000000000001946 120.0
TH1_k127_9706367_9 dehydratase - - - 0.00000000000000000000000000003538 121.0