Overview

ID MAG03899
Name TH2_bin.19
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family
Genus
Species
Assembly information
Completeness (%) 78.52
Contamination (%) 0.01
GC content (%) 60.0
N50 (bp) 16,102
Genome size (bp) 1,784,600

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1645

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1011860_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1216.0
TH2_k127_1011860_1 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 509.0
TH2_k127_1011860_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000001001 211.0
TH2_k127_1011860_3 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000006361 152.0
TH2_k127_1011860_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000009017 145.0
TH2_k127_1011860_5 nucleotidyltransferase activity K07075 - - 0.00000000000000000000000003856 114.0
TH2_k127_1137498_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.135e-311 971.0
TH2_k127_1137498_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.367e-230 721.0
TH2_k127_1137498_2 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 419.0
TH2_k127_1137498_3 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002845 278.0
TH2_k127_1137498_4 SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003513 272.0
TH2_k127_1137498_5 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000008236 154.0
TH2_k127_1137498_6 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000009152 136.0
TH2_k127_1137498_7 methyltransferase K03774,K03775 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000001271 137.0
TH2_k127_1142658_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1268.0
TH2_k127_1142658_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1180.0
TH2_k127_1142658_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 564.0
TH2_k127_1142658_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 406.0
TH2_k127_1142658_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 340.0
TH2_k127_1142658_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 316.0
TH2_k127_1142658_6 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 297.0
TH2_k127_1142658_7 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000002312 177.0
TH2_k127_1142658_8 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000000000000000000000000001399 175.0
TH2_k127_1142658_9 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000001848 139.0
TH2_k127_1142977_0 Aminotransferase class-III K01845 - 5.4.3.8 3.346e-201 635.0
TH2_k127_1142977_1 Polysulphide reductase, NrfD - - - 1.73e-200 631.0
TH2_k127_1142977_10 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000006578 196.0
TH2_k127_1142977_11 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.000000000000000000000000000000000000000000000000889 180.0
TH2_k127_1142977_12 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000652 174.0
TH2_k127_1142977_13 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000000008776 164.0
TH2_k127_1142977_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000003646 164.0
TH2_k127_1142977_15 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000003594 162.0
TH2_k127_1142977_16 protein complex oligomerization - - - 0.000000000000000000000000000002283 128.0
TH2_k127_1142977_17 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000000000001136 119.0
TH2_k127_1142977_18 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000002146 70.0
TH2_k127_1142977_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 510.0
TH2_k127_1142977_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 433.0
TH2_k127_1142977_4 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 431.0
TH2_k127_1142977_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 432.0
TH2_k127_1142977_6 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 364.0
TH2_k127_1142977_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 303.0
TH2_k127_1142977_8 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000004587 217.0
TH2_k127_1142977_9 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000001569 213.0
TH2_k127_1153275_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1251.0
TH2_k127_1153275_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.066e-248 797.0
TH2_k127_1153275_10 - - - - 0.00000000000000000000000000000000000001107 153.0
TH2_k127_1153275_11 COG3209 Rhs family protein - - - 0.000000000000000000000000000000002529 142.0
TH2_k127_1153275_12 cellulase activity K12287 - - 0.0000000000000001923 89.0
TH2_k127_1153275_14 Prokaryotic N-terminal methylation motif - - - 0.00000002101 55.0
TH2_k127_1153275_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 297.0
TH2_k127_1153275_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000002151 232.0
TH2_k127_1153275_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000007524 213.0
TH2_k127_1153275_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000002547 229.0
TH2_k127_1153275_6 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000007178 199.0
TH2_k127_1153275_7 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000000005152 193.0
TH2_k127_1153275_8 Thioredoxin-like - - - 0.000000000000000000000000000000000000000002698 162.0
TH2_k127_1153275_9 Poly-gamma-glutamate hydrolase - - - 0.000000000000000000000000000000000000000003437 162.0
TH2_k127_1159870_0 PD-(D/E)XK nuclease superfamily - - - 1.298e-219 717.0
TH2_k127_1159870_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 9.629e-201 630.0
TH2_k127_1159870_2 Belongs to the helicase family. UvrD subfamily - - - 1.163e-200 659.0
TH2_k127_1159870_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 344.0
TH2_k127_1159870_4 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003334 271.0
TH2_k127_1159870_5 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000002548 218.0
TH2_k127_1159870_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000005365 168.0
TH2_k127_1163785_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.34e-221 693.0
TH2_k127_1163785_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 408.0
TH2_k127_1163785_10 PFAM response regulator receiver K07657 - - 0.000000000000000000002927 101.0
TH2_k127_1163785_11 Outer membrane efflux protein - - - 0.0000000000002958 74.0
TH2_k127_1163785_12 Cytochrome c7 and related cytochrome c - - - 0.000000002365 59.0
TH2_k127_1163785_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 305.0
TH2_k127_1163785_3 CHASE2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001232 306.0
TH2_k127_1163785_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001293 237.0
TH2_k127_1163785_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003275 238.0
TH2_k127_1163785_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000034 226.0
TH2_k127_1163785_7 CTP:tRNA cytidylyltransferase activity K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000954 205.0
TH2_k127_1163785_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000004353 179.0
TH2_k127_1163785_9 YtkA-like - - - 0.00000000000000000000000004316 117.0
TH2_k127_1245136_0 ImcF-related N-terminal domain K11891 - - 0.0 1297.0
TH2_k127_1245136_1 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 3.386e-262 813.0
TH2_k127_1245136_10 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000000000000000000000000000000003303 238.0
TH2_k127_1245136_11 ImpA, N-terminal, type VI secretion system K11910 - - 0.00000000000000000000000000000000000000000000000000000003543 209.0
TH2_k127_1245136_12 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.000000000000000000000000000000000000000000000000000458 194.0
TH2_k127_1245136_13 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 - - - 0.000000000000000000000000000000000000000000000000007624 188.0
TH2_k127_1245136_14 - - - - 0.00000000000000000000000000000000000004769 153.0
TH2_k127_1245136_15 Gene 25-like lysozyme K11897 - - 0.000000000000000000000000000000000000171 147.0
TH2_k127_1245136_16 Type VI secretion system effector, Hcp K11903 - - 0.00000000000000000000000000000000001172 141.0
TH2_k127_1245136_18 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.000000004107 57.0
TH2_k127_1245136_2 Type VI secretion system, TssF K11896 - - 4.929e-243 764.0
TH2_k127_1245136_3 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 604.0
TH2_k127_1245136_4 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 609.0
TH2_k127_1245136_5 ImpA, N-terminal, type VI secretion system K11902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 418.0
TH2_k127_1245136_6 Type VI secretion system protein DotU K11892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
TH2_k127_1245136_7 type VI secretion protein K11895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008014 282.0
TH2_k127_1245136_8 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000168 265.0
TH2_k127_1245136_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008462 274.0
TH2_k127_1281624_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1242.0
TH2_k127_1281624_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 462.0
TH2_k127_1281624_2 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 404.0
TH2_k127_1281624_3 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 404.0
TH2_k127_1281624_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 344.0
TH2_k127_1281624_5 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000002534 198.0
TH2_k127_1281624_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000001425 86.0
TH2_k127_132276_0 Psort location CytoplasmicMembrane, score K01990,K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 250.0
TH2_k127_132276_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000005107 225.0
TH2_k127_132276_2 Transport permease protein K01992,K09690 - - 0.000000000000000000000000000000000000000000000000003344 191.0
TH2_k127_132276_3 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000003734 169.0
TH2_k127_132276_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000008398 171.0
TH2_k127_132276_5 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.00000000000000000000000000000000000002727 160.0
TH2_k127_132276_6 Sulfatase - - - 0.00000000000000000000000002794 126.0
TH2_k127_1355647_0 FtsX-like permease family K02004 - - 1.596e-301 943.0
TH2_k127_1355647_1 hexose biosynthetic process K01810 - 5.3.1.9 2.029e-288 893.0
TH2_k127_1355647_10 Ferritin Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 293.0
TH2_k127_1355647_11 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005545 250.0
TH2_k127_1355647_12 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000206 223.0
TH2_k127_1355647_13 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000001035 203.0
TH2_k127_1355647_14 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000001266 187.0
TH2_k127_1355647_15 HDOD domain - - - 0.000000000000000000000000000000000000000000001104 176.0
TH2_k127_1355647_16 - - - - 0.0000000000000000000000722 106.0
TH2_k127_1355647_17 Protein of unknown function (DUF3187) - - - 0.0000000000000000000002741 109.0
TH2_k127_1355647_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 3.555e-235 743.0
TH2_k127_1355647_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 537.0
TH2_k127_1355647_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 391.0
TH2_k127_1355647_5 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 381.0
TH2_k127_1355647_6 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 354.0
TH2_k127_1355647_7 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 358.0
TH2_k127_1355647_8 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 347.0
TH2_k127_1355647_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 353.0
TH2_k127_1356538_0 SMART Elongator protein 3 MiaB NifB - - - 1.526e-240 748.0
TH2_k127_1356538_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 499.0
TH2_k127_1356538_10 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000005518 222.0
TH2_k127_1356538_11 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000556 218.0
TH2_k127_1356538_12 biosynthesis glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000008397 205.0
TH2_k127_1356538_13 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000002835 195.0
TH2_k127_1356538_14 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.0000000000000000000000000000000000000009412 160.0
TH2_k127_1356538_16 protein with SCP PR1 domains - - - 0.000000000000000001581 93.0
TH2_k127_1356538_17 COG3307 Lipid A core - O-antigen ligase and related enzymes K02847 - - 0.00003043 56.0
TH2_k127_1356538_2 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 440.0
TH2_k127_1356538_3 Domain of unknown function (DUF3413) K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 388.0
TH2_k127_1356538_4 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 362.0
TH2_k127_1356538_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 314.0
TH2_k127_1356538_6 PFAM glycosyl transferase, family 9 K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 292.0
TH2_k127_1356538_7 transferase activity, transferring glycosyl groups K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 291.0
TH2_k127_1356538_8 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 277.0
TH2_k127_1356538_9 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000006287 225.0
TH2_k127_1417433_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.222e-264 850.0
TH2_k127_1417433_1 Highly conserved protein containing a thioredoxin domain K06888 - - 1.176e-237 751.0
TH2_k127_1417433_10 NHL repeat - - - 0.0000000000000000000000000000000004598 151.0
TH2_k127_1417433_11 domain protein - - - 0.00000000000000000000000000000003054 147.0
TH2_k127_1417433_12 Metallo-peptidase family M12 - - - 0.00000000000000000000000000003971 135.0
TH2_k127_1417433_13 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000005133 116.0
TH2_k127_1417433_14 Subtilase family - - - 0.0000000000000000000001185 115.0
TH2_k127_1417433_15 ABC-type sugar transport system periplasmic component - - - 0.0000000000000000000001571 113.0
TH2_k127_1417433_16 TPR repeat - - - 0.0000000000000000002718 98.0
TH2_k127_1417433_17 cellulase activity K12287 - - 0.0000000000000005554 90.0
TH2_k127_1417433_18 S-layer homology domain - - - 0.000000002116 69.0
TH2_k127_1417433_19 - - - - 0.000005466 49.0
TH2_k127_1417433_2 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 571.0
TH2_k127_1417433_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 482.0
TH2_k127_1417433_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 408.0
TH2_k127_1417433_5 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 366.0
TH2_k127_1417433_6 PFAM Glycosyl transferase family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 311.0
TH2_k127_1417433_7 RmlD substrate binding domain K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847 278.0
TH2_k127_1417433_8 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000009809 264.0
TH2_k127_1417433_9 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000002862 181.0
TH2_k127_1427166_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 538.0
TH2_k127_1427166_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 421.0
TH2_k127_1427166_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000001293 183.0
TH2_k127_1427166_11 - - - - 0.00000000000000000000000000001565 121.0
TH2_k127_1427166_12 - - - - 0.00000000000000000000000001799 112.0
TH2_k127_1427166_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 396.0
TH2_k127_1427166_4 membrane K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 319.0
TH2_k127_1427166_5 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 300.0
TH2_k127_1427166_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000001315 233.0
TH2_k127_1427166_7 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
TH2_k127_1427166_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000001659 201.0
TH2_k127_1427166_9 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000725 205.0
TH2_k127_1462329_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 1.283e-221 697.0
TH2_k127_1462329_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 499.0
TH2_k127_1462329_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000005269 252.0
TH2_k127_1462329_11 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000009046 215.0
TH2_k127_1462329_12 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000006764 208.0
TH2_k127_1462329_13 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000004081 194.0
TH2_k127_1462329_14 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000007938 175.0
TH2_k127_1462329_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000005477 168.0
TH2_k127_1462329_16 chlorophyll binding - - - 0.00000000000000000000000000000000000001441 154.0
TH2_k127_1462329_17 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000001208 139.0
TH2_k127_1462329_18 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000008172 113.0
TH2_k127_1462329_19 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000001419 108.0
TH2_k127_1462329_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 486.0
TH2_k127_1462329_20 Uncharacterized protein family UPF0054 K07042 - - 0.00000000000000000000005928 105.0
TH2_k127_1462329_21 OmpA family - - - 0.0000000000000000001393 89.0
TH2_k127_1462329_22 Protein of unknown function (DUF2905) - - - 0.0000000000000000002817 92.0
TH2_k127_1462329_23 GlcNAc transferase - - - 0.000000000000000001043 94.0
TH2_k127_1462329_24 - - - - 0.00000000000000005269 81.0
TH2_k127_1462329_25 Ribbon-helix-helix protein, copG family - - - 0.00000000002488 66.0
TH2_k127_1462329_26 Transposase IS200 like - - - 0.00000156 56.0
TH2_k127_1462329_27 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00001575 55.0
TH2_k127_1462329_3 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 359.0
TH2_k127_1462329_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 334.0
TH2_k127_1462329_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 335.0
TH2_k127_1462329_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 314.0
TH2_k127_1462329_7 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 288.0
TH2_k127_1462329_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005876 279.0
TH2_k127_1462329_9 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003549 280.0
TH2_k127_1525786_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1039.0
TH2_k127_1525786_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 7.57e-321 1000.0
TH2_k127_1525786_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000004296 147.0
TH2_k127_1525786_11 RDD family - - - 0.0000000000000000000000000003083 118.0
TH2_k127_1525786_2 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 590.0
TH2_k127_1525786_3 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 508.0
TH2_k127_1525786_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 459.0
TH2_k127_1525786_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 443.0
TH2_k127_1525786_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 376.0
TH2_k127_1525786_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000001218 239.0
TH2_k127_1525786_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000001241 214.0
TH2_k127_1525786_9 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000006156 189.0
TH2_k127_154294_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.537e-214 678.0
TH2_k127_154294_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 5.489e-199 631.0
TH2_k127_154294_10 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000002647 212.0
TH2_k127_154294_11 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000136 176.0
TH2_k127_154294_12 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000002806 153.0
TH2_k127_154294_13 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000001584 109.0
TH2_k127_154294_14 Proteasome subunit K01419 - 3.4.25.2 0.0000000000000000000001725 102.0
TH2_k127_154294_15 - - - - 0.000000000000000000006683 96.0
TH2_k127_154294_16 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000003526 80.0
TH2_k127_154294_17 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000927 76.0
TH2_k127_154294_18 - - - - 0.0000001698 57.0
TH2_k127_154294_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 487.0
TH2_k127_154294_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 496.0
TH2_k127_154294_4 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 413.0
TH2_k127_154294_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 409.0
TH2_k127_154294_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 356.0
TH2_k127_154294_7 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 341.0
TH2_k127_154294_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005715 280.0
TH2_k127_154294_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 276.0
TH2_k127_1643968_0 Glycosyl hydrolase family 57 - - - 6.318e-226 723.0
TH2_k127_1643968_1 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 346.0
TH2_k127_1643968_2 binding domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 330.0
TH2_k127_1643968_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000007882 183.0
TH2_k127_1643968_4 Enzyme of the cupin superfamily K06995 - - 0.000000000000000000000000000003096 122.0
TH2_k127_1643968_5 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000549 60.0
TH2_k127_1643968_6 cell cycle K05589,K12065,K13052 - - 0.0000001293 58.0
TH2_k127_1759753_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 345.0
TH2_k127_1759753_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000000000000000000000000000000001863 187.0
TH2_k127_1759753_2 - - - - 0.00000000000000000000000000000005666 125.0
TH2_k127_1759753_3 GAF domain - - - 0.0000000000000000000000000000008022 136.0
TH2_k127_1759753_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000002831 126.0
TH2_k127_193290_0 Aminotransferase K00814,K14260 GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0040007,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000199 235.0
TH2_k127_193290_1 Protein of unknown function (DUF3617) - - - 0.0000000000000000002874 93.0
TH2_k127_193290_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.000000000001425 70.0
TH2_k127_197708_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 3.648e-279 865.0
TH2_k127_197708_1 Von Willebrand factor type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 493.0
TH2_k127_197708_10 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000003113 55.0
TH2_k127_197708_11 Domain of unknown function (DUF4262) - - - 0.00000003286 61.0
TH2_k127_197708_12 gag-polyprotein putative aspartyl protease K06985 - - 0.0000005238 59.0
TH2_k127_197708_2 CbbQ/NirQ/NorQ C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 392.0
TH2_k127_197708_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 332.0
TH2_k127_197708_4 PFAM metal-dependent phosphohydrolase HD sub - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 330.0
TH2_k127_197708_5 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 328.0
TH2_k127_197708_6 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 298.0
TH2_k127_197708_7 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 289.0
TH2_k127_197708_8 PFAM RES domain - - - 0.0000000000000000000000000000000007121 137.0
TH2_k127_197708_9 Protein of unknown function (DUF2384) - - - 0.0000000000001462 78.0
TH2_k127_2081000_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 0.0 1163.0
TH2_k127_2081000_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 492.0
TH2_k127_2081000_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 470.0
TH2_k127_2081000_3 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000003166 242.0
TH2_k127_2081000_4 Thioredoxin-like - - - 0.000000000000000000000000000000000002496 145.0
TH2_k127_2081000_5 Belongs to the helicase family. UvrD subfamily K03657 - 3.6.4.12 0.000449 46.0
TH2_k127_2131605_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 554.0
TH2_k127_2131605_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 460.0
TH2_k127_2131605_10 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000001188 163.0
TH2_k127_2131605_11 Transposase - - - 0.0000000000000003939 82.0
TH2_k127_2131605_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 464.0
TH2_k127_2131605_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 433.0
TH2_k127_2131605_4 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 381.0
TH2_k127_2131605_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 377.0
TH2_k127_2131605_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 369.0
TH2_k127_2131605_7 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 342.0
TH2_k127_2131605_8 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000193 239.0
TH2_k127_2131605_9 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
TH2_k127_2277374_0 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 433.0
TH2_k127_2277374_1 Peptidase S8 and S53 subtilisin kexin sedolisin K01342,K14645 - 3.4.21.62 0.00000000000000000009514 102.0
TH2_k127_2289416_0 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 595.0
TH2_k127_2289416_1 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 536.0
TH2_k127_2289416_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 442.0
TH2_k127_2289416_3 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 346.0
TH2_k127_2289416_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000006316 241.0
TH2_k127_2289416_5 Response regulator receiver domain - - - 0.00000000000000000000000000201 113.0
TH2_k127_2289416_6 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000003034 104.0
TH2_k127_2399770_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 515.0
TH2_k127_2399770_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 396.0
TH2_k127_2399770_10 Site-specific recombinase - - - 0.000000000405 62.0
TH2_k127_2399770_11 S-layer homology domain - - - 0.000000001221 63.0
TH2_k127_2399770_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 342.0
TH2_k127_2399770_3 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000001341 228.0
TH2_k127_2399770_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000004382 221.0
TH2_k127_2399770_5 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000006545 207.0
TH2_k127_2399770_6 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000001714 191.0
TH2_k127_2399770_7 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000011 144.0
TH2_k127_2399770_9 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000001083 106.0
TH2_k127_2426548_0 Telomere recombination K04656 - - 2.202e-259 823.0
TH2_k127_2426548_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.786e-200 638.0
TH2_k127_2426548_10 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000000000000000006318 188.0
TH2_k127_2426548_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000003029 183.0
TH2_k127_2426548_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000004491 161.0
TH2_k127_2426548_13 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000007344 156.0
TH2_k127_2426548_14 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000009808 134.0
TH2_k127_2426548_15 cell redox homeostasis K02199 - - 0.00000000000000000000000000000003338 134.0
TH2_k127_2426548_16 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000053 124.0
TH2_k127_2426548_17 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000007172 119.0
TH2_k127_2426548_18 nickel cation binding K04651,K19640 - - 0.00000000000000000000000000002003 121.0
TH2_k127_2426548_19 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000403 112.0
TH2_k127_2426548_2 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 348.0
TH2_k127_2426548_20 PFAM NAD-dependent epimerase dehydratase K01710,K01784,K02473,K08678 - 4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.7 0.000000000000000007644 83.0
TH2_k127_2426548_22 Bacterial protein of unknown function (DUF948) - - - 0.0004867 48.0
TH2_k127_2426548_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 316.0
TH2_k127_2426548_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 314.0
TH2_k127_2426548_5 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 299.0
TH2_k127_2426548_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 284.0
TH2_k127_2426548_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001388 218.0
TH2_k127_2426548_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000001166 212.0
TH2_k127_2426548_9 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000468 197.0
TH2_k127_2496888_0 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 320.0
TH2_k127_2496888_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000004283 232.0
TH2_k127_2496888_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000006862 222.0
TH2_k127_2496888_3 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000142 193.0
TH2_k127_2496888_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000003651 115.0
TH2_k127_2682787_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 3.966e-201 637.0
TH2_k127_2682787_1 PEP-CTERM motif - - - 0.00000000000000000001433 100.0
TH2_k127_2746802_0 Pfam Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 548.0
TH2_k127_2746802_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003903 263.0
TH2_k127_2746802_2 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000001717 233.0
TH2_k127_2746802_3 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000000000000000000002524 170.0
TH2_k127_2746802_4 - - - - 0.0000000000002157 74.0
TH2_k127_2746802_5 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000005702 51.0
TH2_k127_2815694_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.129e-222 693.0
TH2_k127_2815694_1 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 517.0
TH2_k127_2815694_2 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000001111 180.0
TH2_k127_2815694_3 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000002034 169.0
TH2_k127_2815694_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000009414 159.0
TH2_k127_2815694_5 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000001096 93.0
TH2_k127_2815694_6 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.0002086 51.0
TH2_k127_2866048_0 Domain of unknown function DUF11 - - - 0.0 1292.0
TH2_k127_2866048_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.476e-228 721.0
TH2_k127_2866048_10 exo-alpha-(2->6)-sialidase activity K20276 - - 0.00000000000002017 89.0
TH2_k127_2866048_11 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000005409 81.0
TH2_k127_2866048_12 PFAM regulatory protein AsnC Lrp family - - - 0.000000049 59.0
TH2_k127_2866048_13 Belongs to the peptidase S8 family - - - 0.0000231 59.0
TH2_k127_2866048_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 506.0
TH2_k127_2866048_3 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 428.0
TH2_k127_2866048_4 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000929 287.0
TH2_k127_2866048_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000007387 267.0
TH2_k127_2866048_6 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000001549 243.0
TH2_k127_2866048_7 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step K05985,K07476 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 0.0000000000000000000000000000000000000000000138 168.0
TH2_k127_2866048_8 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000105 109.0
TH2_k127_2866048_9 - - - - 0.00000000000000000000001333 105.0
TH2_k127_2869633_0 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 507.0
TH2_k127_2869633_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 512.0
TH2_k127_2869633_10 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000002672 173.0
TH2_k127_2869633_11 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000003132 161.0
TH2_k127_2869633_12 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03774,K03775 - 5.2.1.8 0.0000000000000000000000000000000003818 138.0
TH2_k127_2869633_13 Membrane - - - 0.00000000000000000000000002893 112.0
TH2_k127_2869633_14 Transcriptional regulator, LysR - - - 0.000000000000000003704 96.0
TH2_k127_2869633_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 383.0
TH2_k127_2869633_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 352.0
TH2_k127_2869633_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 352.0
TH2_k127_2869633_5 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 306.0
TH2_k127_2869633_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 286.0
TH2_k127_2869633_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003871 250.0
TH2_k127_2869633_8 lytic transglycosylase K08309 - - 0.000000000000000000000000000000000000000000000000000000000000002335 240.0
TH2_k127_2869633_9 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000003237 172.0
TH2_k127_2983440_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 602.0
TH2_k127_2983440_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 443.0
TH2_k127_2983440_10 iron-sulfur cluster assembly - - - 0.0000000000000000000000001955 107.0
TH2_k127_2983440_11 General secretion pathway protein C K02452 - - 0.0000000000000000003181 98.0
TH2_k127_2983440_2 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 370.0
TH2_k127_2983440_3 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 371.0
TH2_k127_2983440_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 347.0
TH2_k127_2983440_5 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 349.0
TH2_k127_2983440_6 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 341.0
TH2_k127_2983440_7 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 338.0
TH2_k127_2983440_8 Belongs to the MurCDEF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 336.0
TH2_k127_2983440_9 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000001202 169.0
TH2_k127_3125140_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 429.0
TH2_k127_3125140_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 401.0
TH2_k127_3125140_10 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008382 272.0
TH2_k127_3125140_11 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001862 269.0
TH2_k127_3125140_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000006296 247.0
TH2_k127_3125140_13 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000004701 232.0
TH2_k127_3125140_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000145 231.0
TH2_k127_3125140_15 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000006258 226.0
TH2_k127_3125140_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005538 201.0
TH2_k127_3125140_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002961 196.0
TH2_k127_3125140_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003919 192.0
TH2_k127_3125140_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000002889 177.0
TH2_k127_3125140_2 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 405.0
TH2_k127_3125140_20 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000001166 171.0
TH2_k127_3125140_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000001016 168.0
TH2_k127_3125140_22 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001741 168.0
TH2_k127_3125140_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000004178 153.0
TH2_k127_3125140_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000005799 153.0
TH2_k127_3125140_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000004884 149.0
TH2_k127_3125140_26 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000009912 147.0
TH2_k127_3125140_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001604 129.0
TH2_k127_3125140_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000061 121.0
TH2_k127_3125140_29 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001316 117.0
TH2_k127_3125140_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 370.0
TH2_k127_3125140_30 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001273 103.0
TH2_k127_3125140_31 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000003822 81.0
TH2_k127_3125140_32 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000467 74.0
TH2_k127_3125140_33 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001722 70.0
TH2_k127_3125140_34 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000167 64.0
TH2_k127_3125140_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 346.0
TH2_k127_3125140_5 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 347.0
TH2_k127_3125140_6 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 332.0
TH2_k127_3125140_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 297.0
TH2_k127_3125140_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 291.0
TH2_k127_3125140_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
TH2_k127_315085_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.2e-223 706.0
TH2_k127_315085_1 Ftsk_gamma K03466 - - 1.741e-207 672.0
TH2_k127_315085_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 4.788e-200 637.0
TH2_k127_315085_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005187 260.0
TH2_k127_315085_4 NOG31153 non supervised orthologous group - - - 0.00000000000000002303 86.0
TH2_k127_315085_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000003784 83.0
TH2_k127_3348394_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 528.0
TH2_k127_3348394_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 510.0
TH2_k127_3348394_10 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 305.0
TH2_k127_3348394_11 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 298.0
TH2_k127_3348394_12 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001715 286.0
TH2_k127_3348394_13 Tetrapyrrole (Corrin/Porphyrin) Methylases K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003454 293.0
TH2_k127_3348394_14 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001601 287.0
TH2_k127_3348394_15 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006362 266.0
TH2_k127_3348394_16 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000574 261.0
TH2_k127_3348394_17 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000004407 256.0
TH2_k127_3348394_18 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000009381 224.0
TH2_k127_3348394_19 TIGRFAM precorrin-2 C20-methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000003566 227.0
TH2_k127_3348394_2 PFAM Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 487.0
TH2_k127_3348394_20 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000001451 213.0
TH2_k127_3348394_21 YbbR-like protein - - - 0.00000000000000000000000000000000000000000000000000000004171 204.0
TH2_k127_3348394_22 Hep Hag repeat protein - - - 0.000000000000000000000000000000000000000000000000000002098 206.0
TH2_k127_3348394_23 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000004186 194.0
TH2_k127_3348394_24 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000001716 190.0
TH2_k127_3348394_25 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000006874 183.0
TH2_k127_3348394_26 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000007058 182.0
TH2_k127_3348394_27 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000003267 178.0
TH2_k127_3348394_28 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000000000004699 164.0
TH2_k127_3348394_29 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000002898 166.0
TH2_k127_3348394_3 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 449.0
TH2_k127_3348394_30 Cobalamin-5-phosphate synthase K02233 - 2.7.8.26 0.000000000000000000000000000000000006306 148.0
TH2_k127_3348394_32 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000009672 130.0
TH2_k127_3348394_33 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000004192 102.0
TH2_k127_3348394_34 Regulatory protein, FmdB family - - - 0.000000000000000000002248 94.0
TH2_k127_3348394_35 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - 0.0000000000000000000253 93.0
TH2_k127_3348394_36 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000006059 104.0
TH2_k127_3348394_37 energy transducer activity K03646,K03832 - - 0.0000000000000000005292 96.0
TH2_k127_3348394_38 S-layer homology domain - - - 0.00000003956 64.0
TH2_k127_3348394_4 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 394.0
TH2_k127_3348394_40 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000004417 59.0
TH2_k127_3348394_5 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 391.0
TH2_k127_3348394_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 344.0
TH2_k127_3348394_7 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 363.0
TH2_k127_3348394_8 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 317.0
TH2_k127_3348394_9 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 317.0
TH2_k127_3401855_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 4.678e-222 708.0
TH2_k127_3401855_1 Cellulose biosynthesis protein BcsQ K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009419 282.0
TH2_k127_3401855_10 Flagellar biosynthetic protein FliQ K02420 - - 0.000000000000000114 90.0
TH2_k127_3401855_11 Fibronectin type III and ankyrin repeat domains 1 - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005929,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010941,GO:0010942,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0042981,GO:0042995,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051090,GO:0051091,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097546,GO:0120025,GO:0120038,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0004362 43.0
TH2_k127_3401855_2 FliP family K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001468 251.0
TH2_k127_3401855_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005534 255.0
TH2_k127_3401855_4 flagellar motor switch protein FliM K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002057 255.0
TH2_k127_3401855_5 sigma factor activity K02405,K03093 - - 0.00000000000000000000000000000000000000000000000001739 195.0
TH2_k127_3401855_6 GTP-binding signal recognition particle SRP54 K02404 - - 0.0000000000000000000000000000000000000000000000002449 190.0
TH2_k127_3401855_7 PFAM surface presentation of antigens (SPOA) protein K02417 - - 0.0000000000000000000000000000000000002585 143.0
TH2_k127_3401855_8 Role in flagellar biosynthesis K02421 - - 0.000000000000000000000000000000003676 138.0
TH2_k127_3401855_9 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000003761 99.0
TH2_k127_3407916_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.121e-318 1004.0
TH2_k127_3407916_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 410.0
TH2_k127_3407916_2 Restriction endonuclease XhoI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 374.0
TH2_k127_3407916_3 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 369.0
TH2_k127_3407916_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588,K01945 - 5.4.99.18,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000002333 244.0
TH2_k127_3407916_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000513 239.0
TH2_k127_3407916_6 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000001316 163.0
TH2_k127_3407916_7 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000008595 152.0
TH2_k127_3412083_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1528.0
TH2_k127_3412083_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 383.0
TH2_k127_3412083_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 333.0
TH2_k127_3412083_3 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 316.0
TH2_k127_3412083_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 286.0
TH2_k127_3412083_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000000000000002507 153.0
TH2_k127_3412083_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000002402 133.0
TH2_k127_3412083_7 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000001488 95.0
TH2_k127_3412083_8 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000005041 63.0
TH2_k127_3412083_9 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000002742 54.0
TH2_k127_3458712_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.615e-268 844.0
TH2_k127_3458712_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 6.686e-245 769.0
TH2_k127_3458712_10 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000003776 160.0
TH2_k127_3458712_12 - - - - 0.00000002017 64.0
TH2_k127_3458712_13 Phosphoribosyl transferase domain K02242 - - 0.000005466 49.0
TH2_k127_3458712_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.366e-242 760.0
TH2_k127_3458712_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 565.0
TH2_k127_3458712_4 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 521.0
TH2_k127_3458712_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 397.0
TH2_k127_3458712_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 361.0
TH2_k127_3458712_7 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 332.0
TH2_k127_3458712_8 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 313.0
TH2_k127_3458712_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000572 251.0
TH2_k127_349808_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 369.0
TH2_k127_349808_1 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008546 264.0
TH2_k127_349808_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000002314 188.0
TH2_k127_349808_3 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000002872 171.0
TH2_k127_349808_4 Histidine kinase - - - 0.000000000000008096 83.0
TH2_k127_3506013_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 7.992e-215 674.0
TH2_k127_3506013_1 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 2.582e-205 650.0
TH2_k127_3506013_2 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 4.107e-202 636.0
TH2_k127_3506013_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 6.386e-195 621.0
TH2_k127_3506013_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 473.0
TH2_k127_3506013_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000002043 228.0
TH2_k127_3506013_6 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000001057 214.0
TH2_k127_3506013_7 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
TH2_k127_3506013_8 amino acid-binding ACT - - - 0.0000000000000000000000000000000000000000000000000000000001527 207.0
TH2_k127_3506013_9 - - - - 0.000000000000000000000000000000000000007852 150.0
TH2_k127_3585199_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 6.433e-195 618.0
TH2_k127_3585199_1 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 385.0
TH2_k127_3585199_10 - - - - 0.00000000000006224 78.0
TH2_k127_3585199_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 326.0
TH2_k127_3585199_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001624 270.0
TH2_k127_3585199_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000008387 167.0
TH2_k127_3585199_5 - - - - 0.00000000000000000000000000000000000003184 152.0
TH2_k127_3585199_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000003706 130.0
TH2_k127_3585199_7 PFAM transposase IS3 IS911 family protein K07483 - - 0.00000000000000000000001136 104.0
TH2_k127_3585199_8 - - - - 0.0000000000000000000002663 101.0
TH2_k127_3585199_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000002101 93.0
TH2_k127_358622_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.736e-246 767.0
TH2_k127_358622_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 490.0
TH2_k127_358622_10 PFAM HNH endonuclease K07451 - - 0.00000000000000000000000000001618 124.0
TH2_k127_358622_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000001282 110.0
TH2_k127_358622_12 Protein of unknown function (DUF507) - - - 0.00000000000000000000000002844 110.0
TH2_k127_358622_13 Cytochrome P460 - - - 0.00000000000000000000000005337 117.0
TH2_k127_358622_15 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 0.0000000000000000002326 90.0
TH2_k127_358622_16 - - - - 0.0000000000000000003118 89.0
TH2_k127_358622_2 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 442.0
TH2_k127_358622_3 Bacterial regulatory protein, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 417.0
TH2_k127_358622_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000003894 224.0
TH2_k127_358622_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000001134 191.0
TH2_k127_358622_6 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000001014 169.0
TH2_k127_358622_7 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.00000000000000000000000000000000000004395 148.0
TH2_k127_358622_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000003083 139.0
TH2_k127_358622_9 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000000008053 122.0
TH2_k127_3680130_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 579.0
TH2_k127_3680130_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 541.0
TH2_k127_3680130_2 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 396.0
TH2_k127_3680130_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 308.0
TH2_k127_3680130_4 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000002416 135.0
TH2_k127_3680130_5 EamA-like transporter family - - - 0.00000000000000000000000009467 117.0
TH2_k127_3680130_6 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000003114 108.0
TH2_k127_3680130_7 pseudouridine synthase activity K06176 - 5.4.99.27 0.00000000000000000000004937 101.0
TH2_k127_3741196_0 Domain of unknown function (DUF4139) - - - 4.73e-197 625.0
TH2_k127_3741196_1 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 606.0
TH2_k127_3741196_10 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0000003794 62.0
TH2_k127_3741196_11 General secretion pathway protein H K02457 - - 0.00002192 53.0
TH2_k127_3741196_12 Subtilase family K08651 - 3.4.21.66 0.0002645 47.0
TH2_k127_3741196_2 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000007548 226.0
TH2_k127_3741196_3 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000003252 200.0
TH2_k127_3741196_4 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000001436 207.0
TH2_k127_3741196_5 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000000002094 128.0
TH2_k127_3741196_6 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000001358 113.0
TH2_k127_3741196_7 - - - - 0.000000000006032 76.0
TH2_k127_3741196_8 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000801 61.0
TH2_k127_3741196_9 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - 0.0000001274 62.0
TH2_k127_3778300_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006246 241.0
TH2_k127_3778300_1 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000003825 199.0
TH2_k127_3778300_2 Methyltransferase domain - - - 0.00000000000000000000002042 104.0
TH2_k127_3778300_3 Glycosyltransferase Family 4 - - - 0.0000000000000000007086 99.0
TH2_k127_3799751_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.271e-315 975.0
TH2_k127_3799751_1 Sensory domain found in PocR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 329.0
TH2_k127_3799751_2 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004545 261.0
TH2_k127_3799751_3 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000001486 153.0
TH2_k127_3805695_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 610.0
TH2_k127_3805695_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 531.0
TH2_k127_3805695_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 372.0
TH2_k127_3805695_3 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000003278 244.0
TH2_k127_3805695_4 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000007048 256.0
TH2_k127_3805695_5 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000007993 195.0
TH2_k127_3805695_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000423 194.0
TH2_k127_3805695_7 Belongs to the 'phage' integrase family - - - 0.000000000000000002557 87.0
TH2_k127_3817160_0 Elongation factor G, domain IV K02355 - - 2.209e-313 973.0
TH2_k127_3817160_1 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 1.618e-261 821.0
TH2_k127_3817160_10 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 420.0
TH2_k127_3817160_11 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 402.0
TH2_k127_3817160_12 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 312.0
TH2_k127_3817160_13 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 295.0
TH2_k127_3817160_14 Histidine kinase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001969 263.0
TH2_k127_3817160_15 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000009105 245.0
TH2_k127_3817160_16 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000001545 191.0
TH2_k127_3817160_17 chemotaxis K03408 - - 0.0000000000000000000000000000000000000008321 152.0
TH2_k127_3817160_18 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000004429 145.0
TH2_k127_3817160_19 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000009544 141.0
TH2_k127_3817160_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.134e-252 786.0
TH2_k127_3817160_20 ThiS family K03636 - - 0.000000000000000000000000000000000592 132.0
TH2_k127_3817160_23 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000009187 126.0
TH2_k127_3817160_24 NIL - - - 0.000000000000000000000000001201 114.0
TH2_k127_3817160_25 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000018 78.0
TH2_k127_3817160_26 Pilus assembly protein, PilP K02664,K02665 - - 0.0000000002828 68.0
TH2_k127_3817160_27 Protein of unknown function (DUF2799) - - - 0.000000001513 64.0
TH2_k127_3817160_28 Protein of unknown function (DUF2799) - - - 0.000000005518 64.0
TH2_k127_3817160_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.696e-246 772.0
TH2_k127_3817160_4 Type II/IV secretion system protein K02454,K02652 - - 3.875e-203 647.0
TH2_k127_3817160_5 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 587.0
TH2_k127_3817160_6 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 508.0
TH2_k127_3817160_7 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 504.0
TH2_k127_3817160_8 Signal transducing histidine kinase homodimeric K03407,K13490 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 515.0
TH2_k127_3817160_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 466.0
TH2_k127_3952258_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 351.0
TH2_k127_3952258_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 333.0
TH2_k127_3952258_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
TH2_k127_3952258_3 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000006892 216.0
TH2_k127_3952258_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000007094 189.0
TH2_k127_3952258_5 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000001838 171.0
TH2_k127_3952258_6 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000001081 152.0
TH2_k127_3952258_7 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.0000000003988 61.0
TH2_k127_3952258_8 E3 Ubiquitin ligase - - - 0.00002071 56.0
TH2_k127_4000575_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 2.622e-296 934.0
TH2_k127_4000575_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.025e-275 867.0
TH2_k127_4000575_10 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000004112 102.0
TH2_k127_4000575_11 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000003253 102.0
TH2_k127_4000575_12 - - - - 0.000000000000001269 83.0
TH2_k127_4000575_13 Helix-turn-helix domain - - - 0.0000001311 58.0
TH2_k127_4000575_15 Transposase IS200 like K07491 - - 0.0007961 44.0
TH2_k127_4000575_2 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.802e-258 807.0
TH2_k127_4000575_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008202 283.0
TH2_k127_4000575_4 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001821 278.0
TH2_k127_4000575_5 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000218 190.0
TH2_k127_4000575_6 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000005892 191.0
TH2_k127_4000575_7 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000004249 146.0
TH2_k127_4000575_8 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000004519 143.0
TH2_k127_4000575_9 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000001874 127.0
TH2_k127_4101366_0 GAF domain - - - 1.333e-240 773.0
TH2_k127_4101366_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 562.0
TH2_k127_4101366_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000003443 230.0
TH2_k127_4101366_11 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000001446 192.0
TH2_k127_4101366_12 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000002213 124.0
TH2_k127_4101366_13 Putative Fe-S cluster K03616 - - 0.0000000000000000003894 91.0
TH2_k127_4101366_2 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 506.0
TH2_k127_4101366_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 494.0
TH2_k127_4101366_4 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 377.0
TH2_k127_4101366_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 351.0
TH2_k127_4101366_6 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 337.0
TH2_k127_4101366_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001132 274.0
TH2_k127_4101366_8 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005231 244.0
TH2_k127_4101366_9 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000002512 224.0
TH2_k127_4108943_0 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 328.0
TH2_k127_4108943_1 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000104 256.0
TH2_k127_4108943_2 Pfam:N_methyl_2 K02671 - - 0.0000000000000001576 85.0
TH2_k127_4108943_3 Prokaryotic N-terminal methylation motif - - - 0.000000000000003387 86.0
TH2_k127_4153771_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1243.0
TH2_k127_4153771_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 421.0
TH2_k127_4153771_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000001741 209.0
TH2_k127_4153771_3 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000003155 201.0
TH2_k127_4153771_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000001057 201.0
TH2_k127_4153771_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000008155 149.0
TH2_k127_4153771_7 Sulfurtransferase TusA - - - 0.00000000000000000000009679 106.0
TH2_k127_4414473_0 cell redox homeostasis - - - 4.976e-220 691.0
TH2_k127_4414473_1 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 332.0
TH2_k127_4414473_2 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 307.0
TH2_k127_4414473_3 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 299.0
TH2_k127_4414473_4 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 289.0
TH2_k127_4414473_5 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000005052 193.0
TH2_k127_4414473_6 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000007566 186.0
TH2_k127_4414473_7 Glycogen debranching enzyme - - - 0.000000000000000000000000000000005689 129.0
TH2_k127_4526881_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.25e-317 977.0
TH2_k127_4526881_1 FMN binding - - - 1.053e-276 857.0
TH2_k127_4526881_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 602.0
TH2_k127_4526881_3 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 583.0
TH2_k127_4526881_4 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 389.0
TH2_k127_4526881_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 389.0
TH2_k127_4526881_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 378.0
TH2_k127_4526881_7 Domain of unknown function (DUF1848) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 347.0
TH2_k127_4526881_8 Nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000002828 177.0
TH2_k127_4563928_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 1.804e-276 857.0
TH2_k127_4563928_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 500.0
TH2_k127_4563928_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 432.0
TH2_k127_4563928_3 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000002084 205.0
TH2_k127_4563928_4 eight transmembrane protein EpsH - - - 0.00000000000000000000000000000000000000000005631 171.0
TH2_k127_4563928_5 VanZ like family - - - 0.000000000000000000000000000000000000000259 164.0
TH2_k127_4563928_6 PIN domain - - - 0.00000000000000000005184 94.0
TH2_k127_4563928_7 PFAM VanZ - - - 0.0000000002409 70.0
TH2_k127_4563928_8 Bacterial antitoxin of type II TA system, VapB - - - 0.0006879 45.0
TH2_k127_4578502_0 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 549.0
TH2_k127_4578502_1 Natural resistance-associated macrophage protein K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 282.0
TH2_k127_4578502_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006774 287.0
TH2_k127_4578502_4 - - - - 0.00000000007052 70.0
TH2_k127_4595347_0 Metallo-peptidase family M12 - - - 0.000000000000000000000003161 121.0
TH2_k127_4595347_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000003961 103.0
TH2_k127_4595347_2 C-terminal, D2-small domain, of ClpB protein K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0000000000000003199 93.0
TH2_k127_4595347_3 PIN domain - - - 0.0000000000000008811 79.0
TH2_k127_4595347_4 alginic acid biosynthetic process K01179 - 3.2.1.4 0.000000000000009122 89.0
TH2_k127_4595347_5 Sigma54 specific transcriptional regulator, Fis family K21405 - - 0.0000002321 64.0
TH2_k127_4604484_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.352e-236 755.0
TH2_k127_4604484_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 9.927e-210 662.0
TH2_k127_4604484_10 methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 397.0
TH2_k127_4604484_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 352.0
TH2_k127_4604484_12 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 325.0
TH2_k127_4604484_13 TIGRFAM radical SAM Cys-rich domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007332 270.0
TH2_k127_4604484_14 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000001707 181.0
TH2_k127_4604484_15 gas vesicle protein - - - 0.00000000000000000001075 96.0
TH2_k127_4604484_16 thiamine diphosphate biosynthetic process K03154 - - 0.000000000001344 69.0
TH2_k127_4604484_17 diguanylate cyclase K21020 - 2.7.7.65 0.00001508 51.0
TH2_k127_4604484_18 PilZ domain - - - 0.0000606 52.0
TH2_k127_4604484_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 606.0
TH2_k127_4604484_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 577.0
TH2_k127_4604484_4 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 482.0
TH2_k127_4604484_5 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 467.0
TH2_k127_4604484_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 462.0
TH2_k127_4604484_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 436.0
TH2_k127_4604484_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 422.0
TH2_k127_4604484_9 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 402.0
TH2_k127_4617151_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.852e-256 795.0
TH2_k127_4617151_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 502.0
TH2_k127_4617151_10 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001648 259.0
TH2_k127_4617151_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001405 244.0
TH2_k127_4617151_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000001005 220.0
TH2_k127_4617151_13 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000002669 212.0
TH2_k127_4617151_14 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000006192 196.0
TH2_k127_4617151_15 HNH endonuclease K07454 - - 0.00000000000000000000000000000000000000000000000000006965 198.0
TH2_k127_4617151_16 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000007506 187.0
TH2_k127_4617151_17 OstA-like protein K09774 - - 0.000000000000000000000000000000000000000000001528 170.0
TH2_k127_4617151_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000137 171.0
TH2_k127_4617151_19 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000000000114 142.0
TH2_k127_4617151_2 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 437.0
TH2_k127_4617151_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000004752 124.0
TH2_k127_4617151_22 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000008673 70.0
TH2_k127_4617151_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 381.0
TH2_k127_4617151_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 353.0
TH2_k127_4617151_5 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 317.0
TH2_k127_4617151_6 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K19170 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 322.0
TH2_k127_4617151_7 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 301.0
TH2_k127_4617151_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 289.0
TH2_k127_4617151_9 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
TH2_k127_4660474_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 563.0
TH2_k127_4660474_1 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 342.0
TH2_k127_4660474_10 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000007632 116.0
TH2_k127_4660474_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000892 247.0
TH2_k127_4660474_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000734 208.0
TH2_k127_4660474_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000001423 155.0
TH2_k127_4660474_5 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000000000003662 154.0
TH2_k127_4660474_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000001253 142.0
TH2_k127_4660474_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000003495 138.0
TH2_k127_4660474_8 Protein of unknown function (DUF1284) K09706 - - 0.000000000000000000000000000000005722 132.0
TH2_k127_4660474_9 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000001289 126.0
TH2_k127_4698991_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 554.0
TH2_k127_4698991_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 469.0
TH2_k127_4698991_2 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 439.0
TH2_k127_4698991_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 395.0
TH2_k127_4698991_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 311.0
TH2_k127_4698991_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 305.0
TH2_k127_4698991_6 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003216 263.0
TH2_k127_4698991_7 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.00000000000000000000000000000000004148 136.0
TH2_k127_4862178_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1058.0
TH2_k127_4862178_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 434.0
TH2_k127_4862178_10 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000001463 190.0
TH2_k127_4862178_11 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000008313 160.0
TH2_k127_4862178_12 Protein of unknown function DUF86 - - - 0.00000000001934 68.0
TH2_k127_4862178_13 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000261 53.0
TH2_k127_4862178_14 sulfur relay protein TusB DsrH K07237 - - 0.000004929 52.0
TH2_k127_4862178_15 Tetratricopeptide repeat protein - - - 0.00001221 55.0
TH2_k127_4862178_16 Sulfur relay protein TusC DsrF K07236 - - 0.00002731 51.0
TH2_k127_4862178_17 DsrE/DsrF-like family K07235 - - 0.00009549 48.0
TH2_k127_4862178_2 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 416.0
TH2_k127_4862178_3 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 380.0
TH2_k127_4862178_4 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 385.0
TH2_k127_4862178_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
TH2_k127_4862178_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 318.0
TH2_k127_4862178_7 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002 258.0
TH2_k127_4862178_8 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000001129 203.0
TH2_k127_4862178_9 Molybdate transporter of MFS superfamily - - - 0.0000000000000000000000000000000000000000000000000000001544 210.0
TH2_k127_4869206_0 C-terminal domain of tail specific protease (DUF3340) K03797 - 3.4.21.102 1.148e-210 674.0
TH2_k127_4869206_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 556.0
TH2_k127_4869206_10 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000001405 174.0
TH2_k127_4869206_11 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000001932 166.0
TH2_k127_4869206_12 YGGT family K02221 - - 0.000000000000000000000000000003966 128.0
TH2_k127_4869206_13 - - - - 0.00000000000000000000000009171 113.0
TH2_k127_4869206_2 DHHA2 domain K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 555.0
TH2_k127_4869206_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 481.0
TH2_k127_4869206_4 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 462.0
TH2_k127_4869206_5 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 343.0
TH2_k127_4869206_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
TH2_k127_4869206_7 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005744 268.0
TH2_k127_4869206_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
TH2_k127_4869206_9 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000000005022 217.0
TH2_k127_4939289_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 337.0
TH2_k127_4939289_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000001592 228.0
TH2_k127_4939289_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000001019 211.0
TH2_k127_4939289_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000009183 218.0
TH2_k127_4939289_4 TIGRFAM polysaccharide pyruvyl transferase CsaB - - - 0.0000000000000000000000000000001532 139.0
TH2_k127_4939289_5 Metallo-peptidase family M12 - - - 0.000000000000000000000004104 120.0
TH2_k127_4939289_6 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000004218 91.0
TH2_k127_4939289_7 COG4124 Beta-mannanase - - - 0.000000000003867 81.0
TH2_k127_4939289_8 6-phosphogluconolactonase activity - - - 0.000002133 62.0
TH2_k127_4941233_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 515.0
TH2_k127_4941233_1 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 450.0
TH2_k127_4941233_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 384.0
TH2_k127_4941233_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002468 285.0
TH2_k127_4941233_4 PFAM Amidohydrolase 2 K01686 - 4.2.1.8 0.000000000000000000000002117 115.0
TH2_k127_4941233_5 phosphorelay signal transduction system - - - 0.000000000000000000001683 95.0
TH2_k127_4941233_6 Belongs to the thioredoxin family K03671 - - 0.00000001723 58.0
TH2_k127_4941233_7 Thioredoxin K03672 - 1.8.1.8 0.00000006976 58.0
TH2_k127_4961058_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 4.591e-202 643.0
TH2_k127_4961058_1 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 612.0
TH2_k127_4961058_10 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
TH2_k127_4961058_11 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003525 270.0
TH2_k127_4961058_12 PFAM Isochorismatase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000002215 216.0
TH2_k127_4961058_13 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000006624 194.0
TH2_k127_4961058_14 translation release factor activity - - - 0.000000000000000000000000000000000000000004677 158.0
TH2_k127_4961058_15 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000009 130.0
TH2_k127_4961058_16 - K07341 - - 0.0000000000000000009276 95.0
TH2_k127_4961058_17 Psort location Cytoplasmic, score - - - 0.000000000000001745 90.0
TH2_k127_4961058_18 Transglycosylase SLT domain - - - 0.0000000006281 69.0
TH2_k127_4961058_19 Belongs to the 'phage' integrase family K04763 - - 0.0003087 50.0
TH2_k127_4961058_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 584.0
TH2_k127_4961058_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 514.0
TH2_k127_4961058_4 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 462.0
TH2_k127_4961058_5 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 413.0
TH2_k127_4961058_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 411.0
TH2_k127_4961058_7 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 404.0
TH2_k127_4961058_8 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 404.0
TH2_k127_4961058_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 327.0
TH2_k127_5030272_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1614.0
TH2_k127_5030272_1 Belongs to the heat shock protein 70 family - - - 2.364e-245 789.0
TH2_k127_5030272_2 Heat shock protein 70 family - - - 1.229e-202 647.0
TH2_k127_5030272_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 403.0
TH2_k127_5030272_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 369.0
TH2_k127_5030272_5 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002763 262.0
TH2_k127_5030272_6 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000000001089 156.0
TH2_k127_5030272_7 - - - - 0.00000000000000000001331 98.0
TH2_k127_5055329_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.057e-243 763.0
TH2_k127_5055329_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 1.994e-226 709.0
TH2_k127_5055329_10 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 310.0
TH2_k127_5055329_11 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001174 239.0
TH2_k127_5055329_12 PIN domain - - - 0.000000000000000000000000000000000000000000000000000000000006808 210.0
TH2_k127_5055329_13 nitric oxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000003559 203.0
TH2_k127_5055329_14 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000000000000000003022 151.0
TH2_k127_5055329_15 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000000005403 131.0
TH2_k127_5055329_16 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000001742 139.0
TH2_k127_5055329_17 protein conserved in bacteria - - - 0.00000000000000000000001486 106.0
TH2_k127_5055329_18 Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000006787 89.0
TH2_k127_5055329_19 - - - - 0.00000000000000005839 87.0
TH2_k127_5055329_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.675e-197 625.0
TH2_k127_5055329_20 - - - - 0.0000000000004009 74.0
TH2_k127_5055329_21 electron transfer activity K05337,K17247 - - 0.000000001106 61.0
TH2_k127_5055329_22 - - - - 0.000000001611 61.0
TH2_k127_5055329_23 Domain of unknown function (DUF4912) K09942 - - 0.0000002613 62.0
TH2_k127_5055329_3 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 596.0
TH2_k127_5055329_4 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 563.0
TH2_k127_5055329_5 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 550.0
TH2_k127_5055329_6 TOBE domain K02019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 411.0
TH2_k127_5055329_7 Cys Met metabolism K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 391.0
TH2_k127_5055329_8 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 323.0
TH2_k127_5055329_9 PFAM Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
TH2_k127_5064828_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2211.0
TH2_k127_5064828_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2002.0
TH2_k127_5064828_10 structural constituent of ribosome K02913 - - 0.00000000000000008707 82.0
TH2_k127_5064828_11 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000001367 80.0
TH2_k127_5064828_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000467 74.0
TH2_k127_5064828_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 369.0
TH2_k127_5064828_3 TrkA-N domain K03455,K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 366.0
TH2_k127_5064828_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001854 273.0
TH2_k127_5064828_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000001542 237.0
TH2_k127_5064828_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000006315 189.0
TH2_k127_5064828_7 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000524 144.0
TH2_k127_5064828_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000156 143.0
TH2_k127_5064828_9 Domain of unknown function (DUF4136) - - - 0.0000000000000000000001802 105.0
TH2_k127_5119696_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 8.388e-240 749.0
TH2_k127_5119696_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 473.0
TH2_k127_5119696_2 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000000001364 213.0
TH2_k127_5119696_3 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000002308 172.0
TH2_k127_5119696_4 - - - - 0.000000000000000000000000000000000000000000002874 175.0
TH2_k127_5119696_5 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000002768 114.0
TH2_k127_5119696_6 carbon dioxide binding K04653,K04654 - - 0.000000002205 62.0
TH2_k127_5119696_7 His Kinase A (phosphoacceptor) domain - - - 0.000005128 56.0
TH2_k127_5222561_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 618.0
TH2_k127_5222561_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 484.0
TH2_k127_5222561_2 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 390.0
TH2_k127_5222561_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 295.0
TH2_k127_5222561_4 epimerase dehydratase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000667 288.0
TH2_k127_5222561_5 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002983 277.0
TH2_k127_5222561_6 - - - - 0.00000000000000000000000000000000000000001118 158.0
TH2_k127_5222561_7 membrane transporter protein K07090 - - 0.00000000000000008761 80.0
TH2_k127_5227263_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.298e-306 958.0
TH2_k127_5227263_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.586e-297 926.0
TH2_k127_5227263_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 448.0
TH2_k127_5227263_11 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 409.0
TH2_k127_5227263_12 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 344.0
TH2_k127_5227263_13 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 347.0
TH2_k127_5227263_14 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 342.0
TH2_k127_5227263_15 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 344.0
TH2_k127_5227263_16 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 351.0
TH2_k127_5227263_17 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 329.0
TH2_k127_5227263_18 Thymidylate synthase complementing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 314.0
TH2_k127_5227263_19 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
TH2_k127_5227263_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 8.908e-259 819.0
TH2_k127_5227263_20 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 287.0
TH2_k127_5227263_21 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000103 287.0
TH2_k127_5227263_22 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001807 258.0
TH2_k127_5227263_23 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000001108 196.0
TH2_k127_5227263_24 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000006047 146.0
TH2_k127_5227263_25 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000000000000000000000000000000002413 149.0
TH2_k127_5227263_26 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000006335 134.0
TH2_k127_5227263_27 Thiamine-binding protein - - - 0.0000000000000000000000000000000002802 134.0
TH2_k127_5227263_28 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000009526 110.0
TH2_k127_5227263_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.772e-195 617.0
TH2_k127_5227263_30 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000003889 88.0
TH2_k127_5227263_32 Abc transporter K02006 - - 0.000000000001189 70.0
TH2_k127_5227263_33 Protein of unknown function (DUF721) - - - 0.0000000003406 67.0
TH2_k127_5227263_35 - - - - 0.0000004377 55.0
TH2_k127_5227263_4 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 612.0
TH2_k127_5227263_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
TH2_k127_5227263_6 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 571.0
TH2_k127_5227263_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 546.0
TH2_k127_5227263_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 466.0
TH2_k127_5227263_9 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 456.0
TH2_k127_5615821_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1420.0
TH2_k127_5615821_1 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 498.0
TH2_k127_5615821_10 - - - - 0.00000000000000000000000000003076 120.0
TH2_k127_5615821_11 Membrane - - - 0.000000000000000000002689 99.0
TH2_k127_5615821_12 Translation initiation factor SUI1 K03113 - - 0.00000000000000000001385 99.0
TH2_k127_5615821_13 Protein of unknown function (DUF2892) - - - 0.00000000000000000006223 93.0
TH2_k127_5615821_14 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000001998 80.0
TH2_k127_5615821_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 465.0
TH2_k127_5615821_3 PFAM tRNA pseudouridine synthase D TruD K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 394.0
TH2_k127_5615821_4 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 383.0
TH2_k127_5615821_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 354.0
TH2_k127_5615821_6 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 289.0
TH2_k127_5615821_7 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002921 280.0
TH2_k127_5615821_8 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005866 259.0
TH2_k127_5615821_9 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000001264 209.0
TH2_k127_5644665_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.619e-292 906.0
TH2_k127_5644665_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 614.0
TH2_k127_5644665_10 - - - - 0.000000000000000008327 85.0
TH2_k127_5644665_11 cell wall hydrolase K01448 - 3.5.1.28 0.0000000000001829 83.0
TH2_k127_5644665_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 426.0
TH2_k127_5644665_3 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 383.0
TH2_k127_5644665_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
TH2_k127_5644665_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 345.0
TH2_k127_5644665_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 321.0
TH2_k127_5644665_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000008364 150.0
TH2_k127_5644665_8 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000002291 139.0
TH2_k127_5736370_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 2.192e-279 881.0
TH2_k127_5736370_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.722e-227 716.0
TH2_k127_5736370_10 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001603 256.0
TH2_k127_5736370_11 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003988 256.0
TH2_k127_5736370_12 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000001874 232.0
TH2_k127_5736370_13 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
TH2_k127_5736370_14 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000004178 216.0
TH2_k127_5736370_15 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000006392 201.0
TH2_k127_5736370_16 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000004639 188.0
TH2_k127_5736370_17 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000003663 163.0
TH2_k127_5736370_18 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.000000000000000000000000000000000001967 147.0
TH2_k127_5736370_19 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.00000000000000000000000000002471 119.0
TH2_k127_5736370_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 583.0
TH2_k127_5736370_20 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000001743 96.0
TH2_k127_5736370_21 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000002254 95.0
TH2_k127_5736370_22 Protein of unknown function (DUF4197) - - - 0.0000000000003809 69.0
TH2_k127_5736370_23 - - - - 0.000000000001929 73.0
TH2_k127_5736370_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 513.0
TH2_k127_5736370_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 460.0
TH2_k127_5736370_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 457.0
TH2_k127_5736370_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 351.0
TH2_k127_5736370_7 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 346.0
TH2_k127_5736370_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 288.0
TH2_k127_5736370_9 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000005577 257.0
TH2_k127_5768854_0 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 522.0
TH2_k127_5768854_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 468.0
TH2_k127_5768854_10 Belongs to the sirtuin family. Class K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001817 267.0
TH2_k127_5768854_12 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003509 256.0
TH2_k127_5768854_13 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000004334 246.0
TH2_k127_5768854_14 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000007268 228.0
TH2_k127_5768854_15 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000004689 199.0
TH2_k127_5768854_16 MarR family transcriptional K15973 - - 0.0000000000000000000000000000000000000000000002729 171.0
TH2_k127_5768854_17 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000007963 156.0
TH2_k127_5768854_18 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000001608 145.0
TH2_k127_5768854_19 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000002428 123.0
TH2_k127_5768854_20 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000363 93.0
TH2_k127_5768854_22 Heavy-metal-associated domain K07213 - - 0.000154 49.0
TH2_k127_5768854_3 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 420.0
TH2_k127_5768854_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 411.0
TH2_k127_5768854_5 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 394.0
TH2_k127_5768854_6 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 347.0
TH2_k127_5768854_7 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 307.0
TH2_k127_5768854_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 288.0
TH2_k127_5768854_9 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
TH2_k127_5812806_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 518.0
TH2_k127_5812806_1 cysteine-tRNA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 446.0
TH2_k127_5812806_2 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 393.0
TH2_k127_5812806_3 Glycosyl transferase group 1 K00696,K13058 GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006332 281.0
TH2_k127_5812806_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000002093 218.0
TH2_k127_5812806_5 protein domain associated with - - - 0.000000000000000000000000000008856 124.0
TH2_k127_5812806_6 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000003404 129.0
TH2_k127_5812806_8 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000001299 108.0
TH2_k127_5824591_0 - K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 441.0
TH2_k127_5824591_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 436.0
TH2_k127_5824591_2 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 420.0
TH2_k127_5824591_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 398.0
TH2_k127_5824591_4 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 395.0
TH2_k127_5824591_5 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 315.0
TH2_k127_5824591_6 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000000218 194.0
TH2_k127_5824591_7 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000024 182.0
TH2_k127_5824591_8 - - - - 0.00005827 55.0
TH2_k127_5876443_0 TonB dependent receptor K02014 - - 3.069e-209 670.0
TH2_k127_5876443_1 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 527.0
TH2_k127_5876443_10 biosynthesis glycosyltransferase - - - 0.00000000000000000000000000000000000001414 149.0
TH2_k127_5876443_11 TonB dependent receptor K02014 - - 0.00003602 48.0
TH2_k127_5876443_2 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 460.0
TH2_k127_5876443_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 359.0
TH2_k127_5876443_4 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 343.0
TH2_k127_5876443_5 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009532 250.0
TH2_k127_5876443_6 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000009644 230.0
TH2_k127_5876443_7 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000613 209.0
TH2_k127_5876443_8 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000001209 169.0
TH2_k127_5876443_9 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000007132 164.0
TH2_k127_5894370_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.364e-256 805.0
TH2_k127_5894370_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 487.0
TH2_k127_5894370_2 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 378.0
TH2_k127_5894370_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 377.0
TH2_k127_5894370_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 361.0
TH2_k127_5894370_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 314.0
TH2_k127_5894370_6 dUTP biosynthetic process K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000003 249.0
TH2_k127_5894370_7 - - - - 0.000000000000000000000000000000000000000000000000000001256 198.0
TH2_k127_5894370_8 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000007831 160.0
TH2_k127_5946093_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1187.0
TH2_k127_5946093_1 TIGRFAM 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 483.0
TH2_k127_5946093_11 deoxyhypusine monooxygenase activity K05386 - - 0.00000000000000001452 90.0
TH2_k127_5946093_12 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000009018 70.0
TH2_k127_5946093_13 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000001359 72.0
TH2_k127_5946093_14 - - - - 0.00000000001468 68.0
TH2_k127_5946093_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 386.0
TH2_k127_5946093_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 377.0
TH2_k127_5946093_4 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000001026 260.0
TH2_k127_5946093_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000002712 233.0
TH2_k127_5946093_6 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000004754 213.0
TH2_k127_5946093_7 TIGRFAM molybdenum cofactor synthesis domain - - - 0.0000000000000000000000000000000000000000000000000000000002734 207.0
TH2_k127_5946093_8 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.000000000000000000000000000001521 134.0
TH2_k127_5946093_9 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000001748 113.0
TH2_k127_6068441_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1328.0
TH2_k127_6068441_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 512.0
TH2_k127_6068441_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 477.0
TH2_k127_6068441_3 Transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 309.0
TH2_k127_6068441_4 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005787 247.0
TH2_k127_6068441_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000004458 239.0
TH2_k127_6068441_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000263 198.0
TH2_k127_6068441_7 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000003978 197.0
TH2_k127_6068441_8 Outer membrane efflux protein K15725 - - 0.0000000000000000000000001142 121.0
TH2_k127_6068441_9 Phosphoadenosine phosphosulfate reductase family K19170 - - 0.00005036 45.0
TH2_k127_6297546_0 pfam abc K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 319.0
TH2_k127_6297546_1 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000000000000002136 151.0
TH2_k127_6297546_2 Transport permease protein K01992,K09690 - - 0.000000000000000000000000000000000003074 147.0
TH2_k127_6297546_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000005213 141.0
TH2_k127_6297546_4 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000009219 128.0
TH2_k127_6297546_5 PFAM Fimbrial assembly K02461 - - 0.000000000005615 78.0
TH2_k127_6297546_6 General secretion pathway protein M K02462 - - 0.000000006821 64.0
TH2_k127_6319614_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 513.0
TH2_k127_6319614_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 403.0
TH2_k127_6319614_10 PFAM FlhB HrpN YscU SpaS Family K04061 - - 0.0000000000000000000000126 102.0
TH2_k127_6319614_11 flagella basal body P-ring formation protein FlgA K02386 - - 0.000000000000000000031 98.0
TH2_k127_6319614_12 Belongs to the bacterial flagellin family K02397 - - 0.000000000133 72.0
TH2_k127_6319614_13 - - - - 0.00000000799 68.0
TH2_k127_6319614_15 COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) K02398 - - 0.000001894 53.0
TH2_k127_6319614_2 flagellar basal-body rod protein FlgG K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 351.0
TH2_k127_6319614_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 359.0
TH2_k127_6319614_4 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 304.0
TH2_k127_6319614_5 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 270.0
TH2_k127_6319614_6 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000002177 222.0
TH2_k127_6319614_7 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000001829 218.0
TH2_k127_6319614_8 PFAM flagellar basal body rod protein K02392 - - 0.000000000000000000000000000000000000001075 160.0
TH2_k127_6319614_9 Peptidase family M23 - - - 0.00000000000000000000000000000000000477 149.0
TH2_k127_6325134_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 558.0
TH2_k127_6325134_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 556.0
TH2_k127_6325134_10 - - - - 0.000004639 51.0
TH2_k127_6325134_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 471.0
TH2_k127_6325134_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 322.0
TH2_k127_6325134_4 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005185 287.0
TH2_k127_6325134_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000001813 218.0
TH2_k127_6325134_6 - - - - 0.0000000000000000000000000000008538 130.0
TH2_k127_6325134_7 - - - - 0.000000000000000000000000000002124 130.0
TH2_k127_6325134_8 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000823 67.0
TH2_k127_6325134_9 - - - - 0.00000009216 58.0
TH2_k127_6733298_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.8e-297 923.0
TH2_k127_6733298_1 B3/4 domain K01890 - 6.1.1.20 4.092e-204 656.0
TH2_k127_6733298_10 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000492 93.0
TH2_k127_6733298_11 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000002151 86.0
TH2_k127_6733298_2 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 491.0
TH2_k127_6733298_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 458.0
TH2_k127_6733298_4 phosphorelay signal transduction system K02584,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 458.0
TH2_k127_6733298_5 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 432.0
TH2_k127_6733298_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
TH2_k127_6733298_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000165 178.0
TH2_k127_6733298_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000001153 160.0
TH2_k127_6733298_9 DNA-binding transcription factor activity K03710 - - 0.000000000000000000000000000000009174 136.0
TH2_k127_6735323_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.457e-321 1007.0
TH2_k127_6735323_1 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 574.0
TH2_k127_6735323_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000003422 102.0
TH2_k127_6735323_11 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000002502 109.0
TH2_k127_6735323_12 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000002248 94.0
TH2_k127_6735323_13 domain protein - - - 0.00000000000000000001793 92.0
TH2_k127_6735323_14 Modulates RecA activity K03565 - - 0.000000003693 64.0
TH2_k127_6735323_15 ATP synthase, subunit b - - - 0.000001307 54.0
TH2_k127_6735323_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 531.0
TH2_k127_6735323_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000004825 228.0
TH2_k127_6735323_4 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.00000000000000000000000000000000000000000000000000000000004832 210.0
TH2_k127_6735323_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000262 197.0
TH2_k127_6735323_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000002475 149.0
TH2_k127_6735323_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001961 143.0
TH2_k127_6735323_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000007507 143.0
TH2_k127_6735323_9 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000000009307 115.0
TH2_k127_676625_0 organic phosphonate transport K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 531.0
TH2_k127_676625_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 522.0
TH2_k127_676625_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 503.0
TH2_k127_676625_3 response to heat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 487.0
TH2_k127_676625_4 phosphorelay sensor kinase activity K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 428.0
TH2_k127_676625_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000003968 208.0
TH2_k127_676625_6 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000001531 180.0
TH2_k127_676625_7 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000009236 142.0
TH2_k127_676625_8 Trypsin-like peptidase domain - - - 0.0000000000000000000000004069 119.0
TH2_k127_676625_9 peptidyl-tyrosine sulfation - - - 0.0000000009267 70.0
TH2_k127_6769202_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 5.928e-228 717.0
TH2_k127_6769202_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 3.404e-204 653.0
TH2_k127_6769202_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 376.0
TH2_k127_6769202_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 349.0
TH2_k127_6769202_12 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 352.0
TH2_k127_6769202_13 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 318.0
TH2_k127_6769202_14 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 305.0
TH2_k127_6769202_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 299.0
TH2_k127_6769202_16 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 302.0
TH2_k127_6769202_17 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001256 283.0
TH2_k127_6769202_18 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009138 272.0
TH2_k127_6769202_19 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002595 254.0
TH2_k127_6769202_2 Nitroreductase - - - 1.102e-198 634.0
TH2_k127_6769202_20 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001335 256.0
TH2_k127_6769202_21 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004545 261.0
TH2_k127_6769202_22 Belongs to the acetokinase family K00929 - 2.7.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000153 268.0
TH2_k127_6769202_23 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000002479 232.0
TH2_k127_6769202_24 tRNA modification K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000177 215.0
TH2_k127_6769202_25 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000001804 200.0
TH2_k127_6769202_26 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000009078 173.0
TH2_k127_6769202_27 Cation efflux family - - - 0.000000000000000000000000000000000000000000007257 170.0
TH2_k127_6769202_28 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000000001808 150.0
TH2_k127_6769202_29 PFAM Ankyrin K21440 - - 0.0000000000000000000000000001443 126.0
TH2_k127_6769202_3 TIGRFAM oligoendopeptidase, pepF M3 family K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 612.0
TH2_k127_6769202_30 - - - - 0.00000000000000000000000001379 120.0
TH2_k127_6769202_31 Type III restriction protein res subunit K01153 - 3.1.21.3 0.000000005963 58.0
TH2_k127_6769202_32 domain, Protein - - - 0.000001197 60.0
TH2_k127_6769202_33 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0003415 49.0
TH2_k127_6769202_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 519.0
TH2_k127_6769202_5 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 488.0
TH2_k127_6769202_6 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 486.0
TH2_k127_6769202_7 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 440.0
TH2_k127_6769202_8 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 405.0
TH2_k127_6769202_9 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 399.0
TH2_k127_6792309_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1133.0
TH2_k127_6792309_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.513e-221 694.0
TH2_k127_6792309_10 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 341.0
TH2_k127_6792309_11 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 339.0
TH2_k127_6792309_12 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 334.0
TH2_k127_6792309_13 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007169 283.0
TH2_k127_6792309_14 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002632 241.0
TH2_k127_6792309_15 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000779 228.0
TH2_k127_6792309_16 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000008648 227.0
TH2_k127_6792309_17 - - - - 0.000000000000000000000000000000000000000000000000000000002577 206.0
TH2_k127_6792309_18 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000455 205.0
TH2_k127_6792309_19 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000004094 161.0
TH2_k127_6792309_2 Protein of unknown function (DUF2867) - - - 4.557e-194 622.0
TH2_k127_6792309_20 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000005713 136.0
TH2_k127_6792309_21 PFAM Outer membrane efflux protein K18139 - - 0.0000000007151 59.0
TH2_k127_6792309_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 571.0
TH2_k127_6792309_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 564.0
TH2_k127_6792309_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 544.0
TH2_k127_6792309_6 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 557.0
TH2_k127_6792309_7 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 457.0
TH2_k127_6792309_8 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 455.0
TH2_k127_6792309_9 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 346.0
TH2_k127_6821457_0 Heat shock 70 kDa protein K04043 - - 2.51e-321 994.0
TH2_k127_6821457_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.472e-244 760.0
TH2_k127_6821457_10 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 334.0
TH2_k127_6821457_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000005437 231.0
TH2_k127_6821457_12 PINc domain ribonuclease K09006 - - 0.000000000000000000000000000000000000000000000000000000000000000009293 234.0
TH2_k127_6821457_13 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000001298 241.0
TH2_k127_6821457_14 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000006103 219.0
TH2_k127_6821457_15 SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000001103 214.0
TH2_k127_6821457_16 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000002182 222.0
TH2_k127_6821457_17 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000001742 171.0
TH2_k127_6821457_18 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000001191 164.0
TH2_k127_6821457_19 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000001647 130.0
TH2_k127_6821457_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.357e-234 734.0
TH2_k127_6821457_20 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000008013 121.0
TH2_k127_6821457_21 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000006093 110.0
TH2_k127_6821457_22 Transport permease protein K01992 - - 0.0000000000000000000000001209 113.0
TH2_k127_6821457_23 Uncharacterized conserved protein (DUF2304) - - - 0.000000007846 63.0
TH2_k127_6821457_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.504e-225 714.0
TH2_k127_6821457_4 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 538.0
TH2_k127_6821457_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 515.0
TH2_k127_6821457_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 486.0
TH2_k127_6821457_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 429.0
TH2_k127_6821457_8 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 413.0
TH2_k127_6821457_9 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 340.0
TH2_k127_6862363_0 Molydopterin dinucleotide binding domain K17050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 619.0
TH2_k127_6862363_1 4Fe-4S dicluster domain K16965 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 355.0
TH2_k127_6862363_2 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000001623 194.0
TH2_k127_6862363_3 Nitrate reductase delta subunit - - - 0.000000000000000000000000008888 119.0
TH2_k127_6862363_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002582 71.0
TH2_k127_6862363_5 Ethylbenzene dehydrogenase K17052 - - 0.000000006189 66.0
TH2_k127_6862363_6 Ethylbenzene dehydrogenase K17052 - - 0.00004683 51.0
TH2_k127_703649_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 466.0
TH2_k127_703649_1 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 460.0
TH2_k127_703649_10 His Kinase A (phosphoacceptor) domain - - - 0.0000008022 59.0
TH2_k127_703649_2 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 436.0
TH2_k127_703649_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 404.0
TH2_k127_703649_4 response regulator receiver K02481,K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 375.0
TH2_k127_703649_5 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 364.0
TH2_k127_703649_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004274 273.0
TH2_k127_703649_7 HDOD domain - - - 0.000000000000000000000000000000000000000000000000002634 192.0
TH2_k127_703649_8 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000007049 189.0
TH2_k127_703649_9 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000001638 95.0
TH2_k127_7104802_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1802.0
TH2_k127_7104802_1 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 602.0
TH2_k127_7104802_2 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000003647 226.0
TH2_k127_7104802_3 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000004332 135.0
TH2_k127_7104802_4 membrane - - - 0.0000000000000000000000000004815 123.0
TH2_k127_7104802_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K07025 - - 0.00000000000000001075 92.0
TH2_k127_7104802_6 Glycine zipper 2TM domain - - - 0.000000001414 66.0
TH2_k127_7104802_7 Belongs to the peptidase S8 family - - - 0.00001101 56.0
TH2_k127_7119574_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.199e-263 829.0
TH2_k127_7119574_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.442e-227 718.0
TH2_k127_7119574_10 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 284.0
TH2_k127_7119574_11 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004926 277.0
TH2_k127_7119574_12 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000003533 213.0
TH2_k127_7119574_13 - - - - 0.0000000000000000000000000000000000000000000000000000001504 205.0
TH2_k127_7119574_14 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000000000001042 161.0
TH2_k127_7119574_15 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000008259 168.0
TH2_k127_7119574_16 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000008112 153.0
TH2_k127_7119574_18 GAF domain K07678,K07716 - 2.7.13.3 0.0000000000000000000000000000000002967 139.0
TH2_k127_7119574_19 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001919 115.0
TH2_k127_7119574_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 563.0
TH2_k127_7119574_20 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000009641 111.0
TH2_k127_7119574_21 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000003955 98.0
TH2_k127_7119574_22 HDOD domain - - - 0.00000000000000001522 86.0
TH2_k127_7119574_24 Histidine Phosphotransfer domain - - - 0.0000000000145 69.0
TH2_k127_7119574_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 516.0
TH2_k127_7119574_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 462.0
TH2_k127_7119574_5 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 424.0
TH2_k127_7119574_6 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 383.0
TH2_k127_7119574_7 Pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 357.0
TH2_k127_7119574_8 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 311.0
TH2_k127_7119574_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 301.0
TH2_k127_7261315_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 8.421e-207 653.0
TH2_k127_7261315_1 FAD binding domain K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 622.0
TH2_k127_7261315_10 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 462.0
TH2_k127_7261315_11 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 426.0
TH2_k127_7261315_12 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 397.0
TH2_k127_7261315_13 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 399.0
TH2_k127_7261315_14 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 375.0
TH2_k127_7261315_15 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 370.0
TH2_k127_7261315_16 NifU-like N terminal domain K04488,K07126,K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 351.0
TH2_k127_7261315_17 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 324.0
TH2_k127_7261315_18 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
TH2_k127_7261315_19 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 305.0
TH2_k127_7261315_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 572.0
TH2_k127_7261315_20 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 309.0
TH2_k127_7261315_21 Creatinase Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 292.0
TH2_k127_7261315_22 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 287.0
TH2_k127_7261315_23 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003115 279.0
TH2_k127_7261315_24 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007567 276.0
TH2_k127_7261315_25 Cytochrome b/b6/petB K03887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001945 276.0
TH2_k127_7261315_26 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000003555 253.0
TH2_k127_7261315_27 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000001241 245.0
TH2_k127_7261315_28 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
TH2_k127_7261315_29 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000009922 232.0
TH2_k127_7261315_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 532.0
TH2_k127_7261315_30 COGs COG1639 signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000002264 229.0
TH2_k127_7261315_31 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000001335 214.0
TH2_k127_7261315_32 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000001836 209.0
TH2_k127_7261315_33 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000002542 207.0
TH2_k127_7261315_34 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000007593 205.0
TH2_k127_7261315_35 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000001591 209.0
TH2_k127_7261315_36 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000007672 176.0
TH2_k127_7261315_37 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000004114 167.0
TH2_k127_7261315_38 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000005149 177.0
TH2_k127_7261315_39 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000005552 158.0
TH2_k127_7261315_4 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 531.0
TH2_k127_7261315_40 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000004875 145.0
TH2_k127_7261315_41 RNA-binding protein containing a PIN domain K06962 - - 0.00000000000000000000000000000000006518 139.0
TH2_k127_7261315_42 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000001075 123.0
TH2_k127_7261315_43 isomerase activity K01821 - 5.3.2.6 0.0000000000000000000000000007666 115.0
TH2_k127_7261315_44 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000001034 114.0
TH2_k127_7261315_45 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000245 112.0
TH2_k127_7261315_46 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000001119 115.0
TH2_k127_7261315_47 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000113 114.0
TH2_k127_7261315_48 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000000007325 110.0
TH2_k127_7261315_49 redox protein regulator of disulfide bond formation K07397 - - 0.000000000000000000000001536 109.0
TH2_k127_7261315_5 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 522.0
TH2_k127_7261315_50 Zinc finger cdgsh-type domain protein - - - 0.000000000000000000000002002 104.0
TH2_k127_7261315_51 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000002013 107.0
TH2_k127_7261315_53 Belongs to the UPF0235 family K09131 - - 0.000000000008229 68.0
TH2_k127_7261315_54 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000002899 61.0
TH2_k127_7261315_55 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000004904 51.0
TH2_k127_7261315_56 LemA family K03744 - - 0.0003834 46.0
TH2_k127_7261315_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 518.0
TH2_k127_7261315_7 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 495.0
TH2_k127_7261315_8 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 492.0
TH2_k127_7261315_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 472.0
TH2_k127_7346255_0 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 618.0
TH2_k127_7346255_1 phosphorelay sensor kinase activity K01120,K01768,K02486,K11356,K11894,K11913 - 2.7.13.3,3.1.4.17,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 509.0
TH2_k127_7346255_2 PFAM Protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 314.0
TH2_k127_7346255_3 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 303.0
TH2_k127_7346255_4 PFAM Protein phosphatase 2C K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000003651 244.0
TH2_k127_7346255_5 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000155 231.0
TH2_k127_7346255_6 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000002352 147.0
TH2_k127_7346255_7 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337,K21008 GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000001688 109.0
TH2_k127_7346255_8 - - - - 0.0000000000000000002693 101.0
TH2_k127_7350608_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 572.0
TH2_k127_7350608_1 ThiF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 361.0
TH2_k127_7350608_10 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.000000000000000000000000002221 116.0
TH2_k127_7350608_11 Response regulator, receiver - - - 0.0000000001376 68.0
TH2_k127_7350608_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 316.0
TH2_k127_7350608_3 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 295.0
TH2_k127_7350608_4 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000145 282.0
TH2_k127_7350608_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000004836 235.0
TH2_k127_7350608_6 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000001285 203.0
TH2_k127_7350608_7 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000612 183.0
TH2_k127_7350608_8 HNH nucleases - - - 0.000000000000000000000000000000000000000000003047 164.0
TH2_k127_7350608_9 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000002308 130.0
TH2_k127_7862470_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 524.0
TH2_k127_7862470_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 520.0
TH2_k127_7862470_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 410.0
TH2_k127_7862470_3 smart pdz dhr glgf - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009772 290.0
TH2_k127_7862470_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000537 274.0
TH2_k127_7862470_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000007283 233.0
TH2_k127_7862470_7 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000001257 130.0
TH2_k127_7862470_8 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000003906 80.0
TH2_k127_786542_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 3.067e-320 995.0
TH2_k127_786542_1 nodulation K00612 - - 5.118e-289 898.0
TH2_k127_786542_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 403.0
TH2_k127_786542_11 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 401.0
TH2_k127_786542_12 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 381.0
TH2_k127_786542_13 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 356.0
TH2_k127_786542_14 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 362.0
TH2_k127_786542_15 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 330.0
TH2_k127_786542_16 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 321.0
TH2_k127_786542_17 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 302.0
TH2_k127_786542_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004423 274.0
TH2_k127_786542_19 thiosulfate sulfurtransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 258.0
TH2_k127_786542_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 5.878e-288 896.0
TH2_k127_786542_20 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000107 250.0
TH2_k127_786542_21 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000007356 242.0
TH2_k127_786542_22 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000002248 239.0
TH2_k127_786542_23 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
TH2_k127_786542_24 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
TH2_k127_786542_25 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000002588 198.0
TH2_k127_786542_26 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000006801 189.0
TH2_k127_786542_27 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000001649 191.0
TH2_k127_786542_28 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000008346 178.0
TH2_k127_786542_29 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000001375 166.0
TH2_k127_786542_3 Elongation factor SelB, winged helix K03833 - - 6.556e-219 702.0
TH2_k127_786542_30 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000002788 169.0
TH2_k127_786542_31 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000118 169.0
TH2_k127_786542_32 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000004964 162.0
TH2_k127_786542_33 PFAM PHP domain - - - 0.00000000000000000000000000000000000006691 150.0
TH2_k127_786542_34 KR domain - - - 0.0000000000000000000000000009716 121.0
TH2_k127_786542_35 Protein of unknown function (DUF1648) - - - 0.000000000000000000000262 104.0
TH2_k127_786542_36 - - - - 0.000000000000001861 77.0
TH2_k127_786542_38 - - - - 0.00000000001099 70.0
TH2_k127_786542_39 Short C-terminal domain K08982 - - 0.0000007346 55.0
TH2_k127_786542_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 552.0
TH2_k127_786542_40 amine dehydrogenase activity - - - 0.000002219 50.0
TH2_k127_786542_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 541.0
TH2_k127_786542_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 484.0
TH2_k127_786542_7 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 471.0
TH2_k127_786542_8 PFAM Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 447.0
TH2_k127_786542_9 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 431.0
TH2_k127_7946536_0 TIGRFAM ATPase, FliI YscN family K02412,K03224 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 507.0
TH2_k127_7946536_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 484.0
TH2_k127_7946536_10 diguanylate cyclase - - - 0.000000000000000000000000002603 118.0
TH2_k127_7946536_11 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000004605 89.0
TH2_k127_7946536_12 PilZ domain - - - 0.00000000000000001177 93.0
TH2_k127_7946536_13 Flagellar assembly protein FliH K02411 - - 0.00000000000001213 81.0
TH2_k127_7946536_14 PFAM MgtE intracellular K02383 - - 0.00000000000001554 81.0
TH2_k127_7946536_15 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000001708 67.0
TH2_k127_7946536_2 Bacterial regulatory protein, Fis family K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 444.0
TH2_k127_7946536_3 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 412.0
TH2_k127_7946536_4 archaeal or bacterial-type flagellum-dependent cell motility K02556 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 312.0
TH2_k127_7946536_5 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001521 279.0
TH2_k127_7946536_6 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003082 258.0
TH2_k127_7946536_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007389 248.0
TH2_k127_7946536_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001255 229.0
TH2_k127_7946536_9 Flagella basal body rod protein K02388 - - 0.00000000000000000000000000000000000002137 149.0
TH2_k127_7950672_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 1.624e-256 814.0
TH2_k127_7950672_1 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 3.885e-253 786.0
TH2_k127_7950672_10 FixH - - - 0.00000000000000007426 91.0
TH2_k127_7950672_11 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.000000000000001142 80.0
TH2_k127_7950672_12 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.000000000000001168 80.0
TH2_k127_7950672_13 PBS lyase HEAT-like repeat - - - 0.000000000002002 70.0
TH2_k127_7950672_15 FixH - - - 0.0000002926 61.0
TH2_k127_7950672_2 UPF0210 protein K09157 - - 2.101e-218 686.0
TH2_k127_7950672_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 429.0
TH2_k127_7950672_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 351.0
TH2_k127_7950672_5 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 337.0
TH2_k127_7950672_6 PFAM amino acid-binding ACT domain protein K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001271 258.0
TH2_k127_7950672_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000004425 161.0
TH2_k127_7950672_8 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000006173 133.0
TH2_k127_7950672_9 Dodecin K09165 - - 0.0000000000000000001857 90.0
TH2_k127_7985378_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 504.0
TH2_k127_7985378_1 glucose sorbosone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 434.0
TH2_k127_7985378_11 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0003668 48.0
TH2_k127_7985378_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 362.0
TH2_k127_7985378_3 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 320.0
TH2_k127_7985378_4 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 305.0
TH2_k127_7985378_5 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007145 265.0
TH2_k127_7985378_6 PFAM ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002724 240.0
TH2_k127_7985378_7 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000000000000001357 190.0
TH2_k127_7985378_9 Protein of unknown function (DUF2628) - - - 0.0000000000000000000000000002931 119.0
TH2_k127_7986411_0 Endoribonuclease that initiates mRNA decay K18682 - - 7.74e-215 678.0
TH2_k127_7986411_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 444.0
TH2_k127_7986411_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004473 265.0
TH2_k127_7986411_11 translation initiation factor activity K03699 - - 0.000000000000000000000000000000000000000000000000000000000000001967 231.0
TH2_k127_7986411_12 phosphinothricin N-acetyltransferase activity K03823 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000001055 221.0
TH2_k127_7986411_13 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000005016 186.0
TH2_k127_7986411_14 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000005294 169.0
TH2_k127_7986411_15 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000002153 119.0
TH2_k127_7986411_2 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 358.0
TH2_k127_7986411_3 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 359.0
TH2_k127_7986411_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 323.0
TH2_k127_7986411_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 321.0
TH2_k127_7986411_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 301.0
TH2_k127_7986411_7 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007452 282.0
TH2_k127_7986411_8 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
TH2_k127_7986411_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001054 289.0
TH2_k127_801253_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1058.0
TH2_k127_801253_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 581.0
TH2_k127_801253_10 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001414 254.0
TH2_k127_801253_11 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000002969 242.0
TH2_k127_801253_12 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000007606 218.0
TH2_k127_801253_13 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000007962 226.0
TH2_k127_801253_14 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000007826 213.0
TH2_k127_801253_15 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002077 198.0
TH2_k127_801253_16 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000003214 189.0
TH2_k127_801253_17 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000001824 170.0
TH2_k127_801253_18 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000006407 156.0
TH2_k127_801253_2 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 562.0
TH2_k127_801253_20 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000004656 118.0
TH2_k127_801253_21 electron transfer activity K05337,K17247 - - 0.0000000000000000000000003058 106.0
TH2_k127_801253_3 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 563.0
TH2_k127_801253_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 544.0
TH2_k127_801253_5 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 447.0
TH2_k127_801253_6 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 427.0
TH2_k127_801253_7 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 406.0
TH2_k127_801253_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 407.0
TH2_k127_801253_9 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
TH2_k127_8078914_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.21e-303 943.0
TH2_k127_8078914_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 572.0
TH2_k127_8078914_10 universal stress protein - - - 0.0000001261 65.0
TH2_k127_8078914_11 type IV pilus modification protein PilV K02458 - - 0.0000009389 61.0
TH2_k127_8078914_2 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 361.0
TH2_k127_8078914_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000002225 226.0
TH2_k127_8078914_4 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000001426 191.0
TH2_k127_8078914_5 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000001319 129.0
TH2_k127_8078914_6 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000002186 123.0
TH2_k127_8078914_7 pilus assembly protein PilW K02459 - - 0.000000000003163 75.0
TH2_k127_8078914_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000002248 56.0
TH2_k127_8078914_9 COG4970 Tfp pilus assembly protein FimT K02457 - - 0.00000006083 61.0
TH2_k127_8106844_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1700.0
TH2_k127_8106844_1 Glycosyl transferase family 21 - - - 3.397e-201 638.0
TH2_k127_8106844_10 ER membrane protein complex subunit - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006457,GO:0008150,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0032991,GO:0034975,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0072546,GO:0098796,GO:0098827 - 0.00008325 55.0
TH2_k127_8106844_2 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 3.062e-200 646.0
TH2_k127_8106844_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 575.0
TH2_k127_8106844_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 370.0
TH2_k127_8106844_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001568 262.0
TH2_k127_8106844_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000007934 246.0
TH2_k127_8106844_8 - - - - 0.0000000000000000000000000000000000000000000000000000000001462 207.0
TH2_k127_8106844_9 nucleotide metabolic process - - - 0.000000000000000000000000000000000004054 145.0
TH2_k127_8139475_0 Protein conserved in bacteria - - - 1.588e-244 781.0
TH2_k127_8139475_1 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 581.0
TH2_k127_8139475_2 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001035 268.0
TH2_k127_8139475_3 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007839 249.0
TH2_k127_8139475_4 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000006203 187.0
TH2_k127_8139475_5 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000006766 191.0
TH2_k127_8139475_6 Diadenylate cyclase - - - 0.0000000000000000000000000000000000000000001295 170.0
TH2_k127_8146336_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1128.0
TH2_k127_8146336_1 Diguanylate cyclase - - - 4.543e-195 637.0
TH2_k127_8146336_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000002567 143.0
TH2_k127_8146336_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000149 79.0
TH2_k127_8146336_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 486.0
TH2_k127_8146336_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 291.0
TH2_k127_8146336_4 COG0644 Dehydrogenases (flavoproteins) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001958 259.0
TH2_k127_8146336_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000003145 243.0
TH2_k127_8146336_6 Histidine kinase K00936,K02030 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000005618 231.0
TH2_k127_8146336_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001029 218.0
TH2_k127_8146336_8 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000006328 207.0
TH2_k127_8146336_9 Universal stress protein family - - - 0.0000000000000000000000000000000000000000001226 164.0
TH2_k127_8242847_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1091.0
TH2_k127_8242847_1 PBP superfamily domain K03750,K07219 - 2.10.1.1 9.577e-252 792.0
TH2_k127_8242847_10 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 344.0
TH2_k127_8242847_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 338.0
TH2_k127_8242847_12 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 301.0
TH2_k127_8242847_13 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002376 270.0
TH2_k127_8242847_14 Protein of unknown function (DUF1460) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004869 258.0
TH2_k127_8242847_15 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002094 249.0
TH2_k127_8242847_16 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000001473 252.0
TH2_k127_8242847_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000007644 247.0
TH2_k127_8242847_18 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005898 237.0
TH2_k127_8242847_19 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000728 254.0
TH2_k127_8242847_2 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 530.0
TH2_k127_8242847_20 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000003118 229.0
TH2_k127_8242847_21 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000009548 213.0
TH2_k127_8242847_22 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000001324 192.0
TH2_k127_8242847_23 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000004226 192.0
TH2_k127_8242847_24 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000006641 187.0
TH2_k127_8242847_25 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000001014 186.0
TH2_k127_8242847_26 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000000000000000000000000000000001036 184.0
TH2_k127_8242847_27 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000145 188.0
TH2_k127_8242847_28 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000009324 168.0
TH2_k127_8242847_29 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000531 171.0
TH2_k127_8242847_3 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 453.0
TH2_k127_8242847_30 Methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000003432 153.0
TH2_k127_8242847_31 Domains HisKA, HATPase_c - - - 0.0000000000000000000000000000000000002031 152.0
TH2_k127_8242847_32 Thioredoxin-like - - - 0.000000000000000000000000000000001341 136.0
TH2_k127_8242847_33 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000004398 111.0
TH2_k127_8242847_34 - - - - 0.000000000000000000000009157 109.0
TH2_k127_8242847_35 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000004964 102.0
TH2_k127_8242847_36 peptidyl-tyrosine sulfation - - - 0.0000000000000000000007458 110.0
TH2_k127_8242847_37 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000001467 97.0
TH2_k127_8242847_39 Protein of unknown function (DUF2845) - - - 0.00000000000000001111 88.0
TH2_k127_8242847_4 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 450.0
TH2_k127_8242847_40 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0001985 54.0
TH2_k127_8242847_5 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 450.0
TH2_k127_8242847_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 440.0
TH2_k127_8242847_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 421.0
TH2_k127_8242847_8 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 362.0
TH2_k127_8242847_9 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 345.0
TH2_k127_8358664_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.669e-295 916.0
TH2_k127_8358664_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 3.178e-275 859.0
TH2_k127_8358664_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 359.0
TH2_k127_8358664_11 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 291.0
TH2_k127_8358664_12 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001123 263.0
TH2_k127_8358664_13 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002678 270.0
TH2_k127_8358664_14 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002572 247.0
TH2_k127_8358664_15 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000002151 238.0
TH2_k127_8358664_16 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000001115 217.0
TH2_k127_8358664_17 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000005781 209.0
TH2_k127_8358664_18 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000001215 200.0
TH2_k127_8358664_19 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.000000000000000000000000000000000000000006658 163.0
TH2_k127_8358664_2 Surface antigen K07277 - - 1.182e-259 851.0
TH2_k127_8358664_20 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000004394 165.0
TH2_k127_8358664_21 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000001777 158.0
TH2_k127_8358664_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.000000000000000000000000000000000171 139.0
TH2_k127_8358664_23 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000001006 130.0
TH2_k127_8358664_24 Type II secretion system protein B K02451 - - 0.0000000000000000005576 99.0
TH2_k127_8358664_25 Mrr N-terminal domain K07448 - - 0.00000000006714 64.0
TH2_k127_8358664_26 - - - - 0.000000001856 61.0
TH2_k127_8358664_3 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 559.0
TH2_k127_8358664_4 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 530.0
TH2_k127_8358664_5 purine nucleobase transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 526.0
TH2_k127_8358664_6 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 520.0
TH2_k127_8358664_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 428.0
TH2_k127_8358664_8 Dehydrogenase E1 component K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 410.0
TH2_k127_8358664_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 357.0
TH2_k127_8432442_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 595.0
TH2_k127_8432442_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 535.0
TH2_k127_8432442_10 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000001247 189.0
TH2_k127_8432442_11 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000004951 145.0
TH2_k127_8432442_12 Cytochrome c - - - 0.000000000000000000000000003135 121.0
TH2_k127_8432442_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000001042 104.0
TH2_k127_8432442_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 420.0
TH2_k127_8432442_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 359.0
TH2_k127_8432442_4 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 306.0
TH2_k127_8432442_5 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 306.0
TH2_k127_8432442_6 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002766 244.0
TH2_k127_8432442_7 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000009486 216.0
TH2_k127_8432442_8 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.00000000000000000000000000000000000000000000000000000000002264 217.0
TH2_k127_8432442_9 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000007155 212.0
TH2_k127_8459446_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1079.0
TH2_k127_8459446_1 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 7.305e-203 649.0
TH2_k127_8459446_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 348.0
TH2_k127_8459446_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 314.0
TH2_k127_8459446_12 PFAM Aminotransferase class I and II K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 286.0
TH2_k127_8459446_13 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002324 281.0
TH2_k127_8459446_14 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000003359 271.0
TH2_k127_8459446_15 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003398 251.0
TH2_k127_8459446_16 2Fe-2S -binding domain K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001313 248.0
TH2_k127_8459446_17 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
TH2_k127_8459446_18 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000000007526 208.0
TH2_k127_8459446_19 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000005235 112.0
TH2_k127_8459446_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 519.0
TH2_k127_8459446_22 - - - - 0.00000000005621 65.0
TH2_k127_8459446_24 - - - - 0.00002382 51.0
TH2_k127_8459446_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 465.0
TH2_k127_8459446_4 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 431.0
TH2_k127_8459446_5 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 396.0
TH2_k127_8459446_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 398.0
TH2_k127_8459446_7 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 372.0
TH2_k127_8459446_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 360.0
TH2_k127_8459446_9 LysM domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 340.0
TH2_k127_8768711_0 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 530.0
TH2_k127_8768711_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 526.0
TH2_k127_8768711_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 357.0
TH2_k127_8768711_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 292.0
TH2_k127_8768711_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000001085 186.0
TH2_k127_8768711_5 Protein of unknown function (DUF3124) - - - 0.00000000000000000000000000000000000000000000003537 174.0
TH2_k127_8768711_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000002225 106.0
TH2_k127_8768711_7 GDP-mannose mannosyl hydrolase activity - - - 0.0000000000000000000123 94.0
TH2_k127_94420_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 595.0
TH2_k127_94420_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 548.0
TH2_k127_94420_10 - - - - 0.0000001062 65.0
TH2_k127_94420_11 - - - - 0.000004384 53.0
TH2_k127_94420_12 Cytochrome c7 and related cytochrome c - - - 0.0001411 45.0
TH2_k127_94420_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 518.0
TH2_k127_94420_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 477.0
TH2_k127_94420_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 379.0
TH2_k127_94420_5 response regulator K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 321.0
TH2_k127_94420_6 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004578 244.0
TH2_k127_94420_7 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000001775 227.0
TH2_k127_94420_8 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000001038 149.0
TH2_k127_94420_9 MacB-like periplasmic core domain K02004 - - 0.000000000000003028 82.0
TH2_k127_980702_0 response regulator K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 446.0
TH2_k127_980702_1 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 389.0
TH2_k127_980702_10 PBP superfamily domain K02040 - - 0.0000000000000000000000000000002849 130.0
TH2_k127_980702_11 - - - - 0.00000000000000006429 87.0
TH2_k127_980702_12 - - - - 0.000000000003381 73.0
TH2_k127_980702_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 321.0
TH2_k127_980702_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 312.0
TH2_k127_980702_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000001445 230.0
TH2_k127_980702_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000579 208.0
TH2_k127_980702_6 2 iron, 2 sulfur cluster binding K01465,K02823,K05784,K17828 - 1.3.1.14,3.5.2.3 0.0000000000000000000000000000000000000000000000000000005325 201.0
TH2_k127_980702_7 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000000001925 192.0
TH2_k127_980702_8 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000009106 173.0
TH2_k127_980702_9 Histidine kinase K07709 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000002185 184.0
TH2_k127_98752_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1096.0
TH2_k127_98752_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 3.467e-199 641.0
TH2_k127_98752_11 protein conserved in bacteria K09973 - - 0.0000000007545 60.0
TH2_k127_98752_2 ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 573.0
TH2_k127_98752_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 499.0
TH2_k127_98752_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 465.0
TH2_k127_98752_5 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 453.0
TH2_k127_98752_6 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 441.0
TH2_k127_98752_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 317.0
TH2_k127_98752_8 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000008893 204.0
TH2_k127_98752_9 Rubrerythrin - - - 0.00000000000000000004139 96.0