Overview

ID MAG03909
Name TH2_bin.4
Sample SMP0101
Taxonomy
Kingdom Bacteria
Phylum Verrucomicrobiota
Class Verrucomicrobiia
Order Palsa-1439
Family
Genus
Species
Assembly information
Completeness (%) 93.92
Contamination (%) 1.34
GC content (%) 61.0
N50 (bp) 16,934
Genome size (bp) 3,439,326

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2869

Gene name Description KEGG GOs EC E-value Score Sequence
TH2_k127_1025779_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000003453 233.0
TH2_k127_1025779_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000004831 137.0
TH2_k127_1025932_0 Protein of unknown function, DUF255 K06888 - - 2.247e-247 782.0
TH2_k127_1025932_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.931e-239 749.0
TH2_k127_1025932_10 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 343.0
TH2_k127_1025932_11 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 337.0
TH2_k127_1025932_12 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 328.0
TH2_k127_1025932_13 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004343 271.0
TH2_k127_1025932_14 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 259.0
TH2_k127_1025932_15 - - - - 0.0000000000000000000000000000000000000000000000000004354 192.0
TH2_k127_1025932_16 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000001693 183.0
TH2_k127_1025932_17 AraC-like ligand binding domain K03490 - - 0.000000000000000000000000000000000000000000000001433 195.0
TH2_k127_1025932_18 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000004971 165.0
TH2_k127_1025932_19 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000175 164.0
TH2_k127_1025932_2 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 477.0
TH2_k127_1025932_20 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000008446 171.0
TH2_k127_1025932_21 Protein of unknown function (DUF3592) - - - 0.000000000000000000000000000000000142 147.0
TH2_k127_1025932_22 solute-binding protein K02027 - - 0.000000000000000000000000000001984 138.0
TH2_k127_1025932_23 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000002649 99.0
TH2_k127_1025932_24 repeat-containing protein - - - 0.000000001746 69.0
TH2_k127_1025932_26 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0005355 53.0
TH2_k127_1025932_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 472.0
TH2_k127_1025932_4 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 451.0
TH2_k127_1025932_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 404.0
TH2_k127_1025932_6 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 412.0
TH2_k127_1025932_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 386.0
TH2_k127_1025932_8 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 393.0
TH2_k127_1025932_9 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 353.0
TH2_k127_1083678_0 PFAM sulfatase K01130 - 3.1.6.1 1.161e-291 900.0
TH2_k127_1083678_1 Protein of unknown function (DUF3604) - - - 2.165e-248 782.0
TH2_k127_1083678_10 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 299.0
TH2_k127_1083678_11 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001339 282.0
TH2_k127_1083678_12 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000001996 215.0
TH2_k127_1083678_13 PFAM regulatory protein LuxR K13041 - - 0.0000000000000000000000000000000000000000000000000000000008049 220.0
TH2_k127_1083678_14 Pfam Response regulator receiver - - - 0.000000000000000000000000000001225 128.0
TH2_k127_1083678_15 Protein of unknown function (DUF3604) - - - 0.00000003198 66.0
TH2_k127_1083678_16 COG3209 Rhs family protein - - - 0.000003188 52.0
TH2_k127_1083678_2 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 559.0
TH2_k127_1083678_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 463.0
TH2_k127_1083678_4 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 445.0
TH2_k127_1083678_5 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 422.0
TH2_k127_1083678_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 351.0
TH2_k127_1083678_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 364.0
TH2_k127_1083678_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 303.0
TH2_k127_1083678_9 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 307.0
TH2_k127_1088472_0 TonB-dependent receptor K02014 - - 1.75e-240 767.0
TH2_k127_1088472_1 MraW methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 422.0
TH2_k127_1088472_10 calcium- and calmodulin-responsive adenylate cyclase activity K10953,K20276 GO:0000166,GO:0000287,GO:0000822,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005576,GO:0006464,GO:0006508,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0008233,GO:0008234,GO:0009405,GO:0009987,GO:0010467,GO:0016043,GO:0016485,GO:0016540,GO:0016787,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0019835,GO:0019836,GO:0020002,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030554,GO:0031640,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033644,GO:0035639,GO:0035821,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043178,GO:0043412,GO:0043624,GO:0043657,GO:0043933,GO:0044003,GO:0044004,GO:0044179,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044279,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046872,GO:0051261,GO:0051604,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0000000000000000000000863 105.0
TH2_k127_1088472_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 389.0
TH2_k127_1088472_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 306.0
TH2_k127_1088472_4 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001144 278.0
TH2_k127_1088472_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000006311 257.0
TH2_k127_1088472_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000009749 206.0
TH2_k127_1088472_7 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000002852 178.0
TH2_k127_1088472_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000002069 117.0
TH2_k127_1088472_9 oxidoreductase activity - - - 0.0000000000000000000000001094 124.0
TH2_k127_1121839_0 Sulfatase - - - 3.773e-212 669.0
TH2_k127_1121839_1 AP endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 565.0
TH2_k127_1121839_10 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.00000000000000000000000000000001792 130.0
TH2_k127_1121839_11 cellulose binding - - - 0.0000000000000000000000016 103.0
TH2_k127_1121839_12 PFAM Response regulator receiver domain - - - 0.000000000000000000001014 100.0
TH2_k127_1121839_13 by Glimmer2 - - - 0.0000000000000002417 87.0
TH2_k127_1121839_15 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000009802 61.0
TH2_k127_1121839_2 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 488.0
TH2_k127_1121839_3 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 413.0
TH2_k127_1121839_4 SRP54-type protein, GTPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 374.0
TH2_k127_1121839_5 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000001048 271.0
TH2_k127_1121839_6 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000008756 216.0
TH2_k127_1121839_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000005268 187.0
TH2_k127_1121839_8 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.000000000000000000000000000000000000000000000002165 198.0
TH2_k127_1121839_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000002263 168.0
TH2_k127_113713_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 357.0
TH2_k127_113713_1 Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000012 221.0
TH2_k127_113713_2 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000001729 198.0
TH2_k127_113713_3 Glycogen debranching enzyme - - - 0.000000000000000001979 91.0
TH2_k127_1152178_0 6-phosphofructokinase activity K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 584.0
TH2_k127_1152178_1 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 464.0
TH2_k127_1152178_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 403.0
TH2_k127_1152178_3 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 314.0
TH2_k127_1152178_4 bile acid:sodium symporter activity K03453 - - 0.00000000000000000000000000000000000000000000000000000000000005209 226.0
TH2_k127_1152178_5 - - - - 0.000000000000000000000000000000000000000000000000223 194.0
TH2_k127_1152178_6 VIT family - - - 0.00000000000000000000000000000000000000000000000031 188.0
TH2_k127_1152178_7 COG3264 Small-conductance mechanosensitive channel K22051 - - 0.0000000000000000000000000000000000000009689 154.0
TH2_k127_1152178_9 Protein of unknown function (DUF2959) - - - 0.0000000000000005189 87.0
TH2_k127_115244_0 Tex-like protein N-terminal domain - - - 1.884e-297 932.0
TH2_k127_115244_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.074e-248 777.0
TH2_k127_115244_10 response to drug K03748 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000004124 101.0
TH2_k127_115244_11 sequence-specific DNA binding - - - 0.00000000000000000000009891 98.0
TH2_k127_115244_12 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000001415 91.0
TH2_k127_115244_13 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000003581 82.0
TH2_k127_115244_2 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 441.0
TH2_k127_115244_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 335.0
TH2_k127_115244_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 304.0
TH2_k127_115244_5 Ketopantoate hydroxymethyltransferase K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000003702 249.0
TH2_k127_115244_6 cell wall hydrolase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000001661 217.0
TH2_k127_115244_7 Protein of unknown function (DUF2959) - - - 0.000000000000000000000000000000000000000000000000000000001857 207.0
TH2_k127_115244_8 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000008228 205.0
TH2_k127_115244_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000003025 123.0
TH2_k127_1156488_0 RQC K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 546.0
TH2_k127_1156488_1 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
TH2_k127_1156488_2 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000005358 224.0
TH2_k127_1156488_3 cellulose binding - - - 0.000000000000000000000000000000000000000000001866 164.0
TH2_k127_1156488_4 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000004828 136.0
TH2_k127_1156488_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000008934 147.0
TH2_k127_1156488_6 HD domain - - - 0.00000000000000000000000006959 117.0
TH2_k127_1156488_7 Flagellar protein FliS K02422 - - 0.000000000000000006024 89.0
TH2_k127_1156488_8 PFAM AsmA family K07289 - - 0.0000003902 63.0
TH2_k127_1156488_9 AsmA-like C-terminal region K07289 - - 0.000001565 61.0
TH2_k127_1163038_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000958 234.0
TH2_k127_1163038_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000001193 168.0
TH2_k127_1163038_2 Diguanylate cyclase - - - 0.000000000000000000000000000004694 138.0
TH2_k127_1183094_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 477.0
TH2_k127_1183094_1 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 333.0
TH2_k127_1183094_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007639 247.0
TH2_k127_1183094_3 PIN domain - - - 0.000000000000000000000000000000000000000000005364 167.0
TH2_k127_1183094_4 - - - - 0.0000000002171 64.0
TH2_k127_1188064_0 Amino acid kinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 551.0
TH2_k127_1188064_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 467.0
TH2_k127_1188064_10 bacteriocin transport K03561 - - 0.000000000000000000000005965 110.0
TH2_k127_1188064_11 Tetratricopeptide repeat - - - 0.00000000000008746 85.0
TH2_k127_1188064_12 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000001514 63.0
TH2_k127_1188064_13 Biopolymer transport protein ExbD/TolR - - - 0.0000006982 56.0
TH2_k127_1188064_14 - - - - 0.0009721 46.0
TH2_k127_1188064_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 424.0
TH2_k127_1188064_3 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 333.0
TH2_k127_1188064_4 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003463 299.0
TH2_k127_1188064_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000005069 217.0
TH2_k127_1188064_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000001768 211.0
TH2_k127_1188064_7 PFAM Prenyltransferase squalene oxidase K01077,K11751 - 3.1.3.1,3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000002485 198.0
TH2_k127_1188064_8 - - - - 0.000000000000000000000000000000000000000000267 165.0
TH2_k127_1188064_9 SPTR CHU large protein - - - 0.000000000000000000000000001245 123.0
TH2_k127_1194114_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 405.0
TH2_k127_1194114_1 Aminotransferase class-III K00833 - 2.6.1.62 0.0000000000000003562 80.0
TH2_k127_1195650_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 6.862e-266 842.0
TH2_k127_1201610_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 6.158e-268 843.0
TH2_k127_1201610_1 von Willebrand factor, type A - - - 1.512e-223 716.0
TH2_k127_1201610_10 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000138 90.0
TH2_k127_1201610_2 PFAM Acetyl-CoA hydrolase transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 574.0
TH2_k127_1201610_3 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 517.0
TH2_k127_1201610_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 479.0
TH2_k127_1201610_5 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 421.0
TH2_k127_1201610_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 357.0
TH2_k127_1201610_7 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 359.0
TH2_k127_1201610_8 SNARE associated Golgi protein K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000004546 216.0
TH2_k127_1201610_9 - - - - 0.00000000000000000000000000000006882 142.0
TH2_k127_1202528_0 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00000000000000000000000000000000000000000000000005051 192.0
TH2_k127_1202528_1 PFAM membrane bound O-acyl transferase MBOAT K19294 - - 0.00000000000000000000000000004541 121.0
TH2_k127_1202528_2 COG3209 Rhs family protein - - - 0.0000000000000007668 92.0
TH2_k127_1210319_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 355.0
TH2_k127_1210319_1 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000001462 155.0
TH2_k127_1210319_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000003105 117.0
TH2_k127_1231134_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 590.0
TH2_k127_1231134_1 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 327.0
TH2_k127_1231134_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000009761 68.0
TH2_k127_1231134_11 serine threonine protein kinase - - - 0.000000003249 68.0
TH2_k127_1231134_2 PFAM type II secretion system K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 312.0
TH2_k127_1231134_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 302.0
TH2_k127_1231134_4 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000006072 215.0
TH2_k127_1231134_5 Pilus assembly protein PilX - - - 0.000000000000000000000000006085 126.0
TH2_k127_1231134_6 - - - - 0.0000000000000000000000005397 114.0
TH2_k127_1231134_7 Serine aminopeptidase, S33 K06889 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.0000000000000000003791 99.0
TH2_k127_1231134_8 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000214 87.0
TH2_k127_1231134_9 PhoP family transcriptional regulator - - - 0.00000000000007055 76.0
TH2_k127_1243262_0 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000003321 173.0
TH2_k127_1243262_1 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000003132 161.0
TH2_k127_1273618_0 thiamine-containing compound biosynthetic process K02051 - - 7.788e-216 684.0
TH2_k127_1273618_1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 424.0
TH2_k127_1273618_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000001514 177.0
TH2_k127_1273618_3 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000001625 173.0
TH2_k127_1273618_4 Cupin domain - - - 0.000000000000000000000000000000000004443 139.0
TH2_k127_1273618_5 xylulokinase activity K00854 - 2.7.1.17 0.000000005574 58.0
TH2_k127_1273618_6 oxidoreductase activity K02674,K07114 - - 0.000008291 56.0
TH2_k127_1276649_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.204e-263 823.0
TH2_k127_1276649_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 371.0
TH2_k127_1276649_2 Cys/Met metabolism PLP-dependent enzyme K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 343.0
TH2_k127_1276649_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002627 259.0
TH2_k127_1276649_4 TIGR00268 family K06864 - - 0.00000000000000000000000000000000000000000000000000000000000002352 220.0
TH2_k127_1276649_5 COGs COG1253 Hemolysins and related protein containing CBS domains - - - 0.000000000000000000000000000000000000000000000000000001634 207.0
TH2_k127_1276649_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000155 209.0
TH2_k127_1276649_7 Sigma-70, region 4 - - - 0.000000000000000000000000000000007289 145.0
TH2_k127_1276649_8 cold-shock protein K03704 - - 0.0000000000000000000001781 101.0
TH2_k127_1277844_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 425.0
TH2_k127_1277844_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000008355 243.0
TH2_k127_1277844_2 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000008285 170.0
TH2_k127_128936_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.025e-223 709.0
TH2_k127_128936_1 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 2.018e-217 681.0
TH2_k127_128936_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 6.667e-200 636.0
TH2_k127_128936_3 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 511.0
TH2_k127_128936_4 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000005469 268.0
TH2_k127_128936_5 KDPG and KHG aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009997 251.0
TH2_k127_128936_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000002321 232.0
TH2_k127_128936_7 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000002257 122.0
TH2_k127_128936_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000385 76.0
TH2_k127_1294916_0 ATP synthase alpha/beta family, beta-barrel domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 511.0
TH2_k127_1294916_1 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 403.0
TH2_k127_1294916_10 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000005289 74.0
TH2_k127_1294916_11 flagellar assembly protein FliH K02411 - - 0.000000009177 67.0
TH2_k127_1294916_12 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - 0.0000002157 54.0
TH2_k127_1294916_13 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000005545 54.0
TH2_k127_1294916_2 FliG middle domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000009953 243.0
TH2_k127_1294916_3 Flagellar basal body rod K02390 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000008865 206.0
TH2_k127_1294916_4 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000001179 143.0
TH2_k127_1294916_5 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000003471 103.0
TH2_k127_1294916_6 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000003688 107.0
TH2_k127_1294916_7 Flagellar hook capping protein - N-terminal region K02389 - - 0.00000000000000000001321 98.0
TH2_k127_1294916_8 Flagellar motor switch protein FliM K02416 - - 0.0000000000000001159 94.0
TH2_k127_1294916_9 PFAM MgtE intracellular - - - 0.0000000000000001772 88.0
TH2_k127_1311353_0 - - - - 2.264e-228 732.0
TH2_k127_1311353_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000003265 158.0
TH2_k127_1311353_2 YMGG-like Gly-zipper - - - 0.00000000002486 66.0
TH2_k127_1313811_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 5.779e-208 662.0
TH2_k127_1313811_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 562.0
TH2_k127_1313811_10 - - - - 0.00000000000000000000000000159 116.0
TH2_k127_1313811_11 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000002364 105.0
TH2_k127_1313811_12 PFAM Forkhead-associated protein - - - 0.000000000629 74.0
TH2_k127_1313811_13 Colicin V production protein K03558 - - 0.0008709 49.0
TH2_k127_1313811_2 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 456.0
TH2_k127_1313811_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 420.0
TH2_k127_1313811_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 346.0
TH2_k127_1313811_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 318.0
TH2_k127_1313811_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001441 282.0
TH2_k127_1313811_7 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000000000000000000000000006428 160.0
TH2_k127_1313811_8 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000002061 172.0
TH2_k127_1313811_9 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000002467 130.0
TH2_k127_1314934_0 Glycogen debranching enzyme - - - 0.0 1493.0
TH2_k127_1314934_1 Sulfate permease family - - - 4.863e-230 725.0
TH2_k127_1314934_2 Sodium/calcium exchanger protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 579.0
TH2_k127_1314934_3 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 472.0
TH2_k127_1314934_4 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000001425 213.0
TH2_k127_1314934_5 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000237 216.0
TH2_k127_1314934_6 Sodium/hydrogen exchanger family - - - 0.0001499 45.0
TH2_k127_1320328_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 2.751e-200 640.0
TH2_k127_1320328_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341,K05559 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 608.0
TH2_k127_1320328_10 subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05569 - - 0.00000000000000000000001356 106.0
TH2_k127_1320328_11 Na+/H+ antiporter subunit K05564,K05571 - - 0.00000000000000000000001579 103.0
TH2_k127_1320328_12 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000009619 105.0
TH2_k127_1320328_13 Multiple resistance and pH regulation protein F K05570 - - 0.0000000004917 64.0
TH2_k127_1320328_14 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00009733 46.0
TH2_k127_1320328_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 525.0
TH2_k127_1320328_3 PFAM NADH Ubiquinone plastoquinone K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 446.0
TH2_k127_1320328_4 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000002673 245.0
TH2_k127_1320328_5 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05559 - - 0.000000000000000000000000000001912 126.0
TH2_k127_1320328_6 PFAM cation antiporter K05569 - - 0.00000000000000000000000000001039 124.0
TH2_k127_1320328_7 - - - - 0.000000000000000000000000004731 122.0
TH2_k127_1320328_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000001748 113.0
TH2_k127_1320328_9 Na+/H+ antiporter subunit K05571 - - 0.00000000000000000000001035 109.0
TH2_k127_134032_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 334.0
TH2_k127_134032_1 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 308.0
TH2_k127_134032_2 ABC-type sugar transport system, ATPase component K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004933 274.0
TH2_k127_134032_3 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000003128 243.0
TH2_k127_134032_4 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000002103 220.0
TH2_k127_134032_5 beta-galactosidase activity K09800 - - 0.00000000002145 78.0
TH2_k127_134032_6 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000005384 49.0
TH2_k127_1396666_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 1.277e-207 655.0
TH2_k127_1396666_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 534.0
TH2_k127_1396666_10 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000173 258.0
TH2_k127_1396666_11 Sigma 54 modulation/S30EA ribosomal protein C terminus K05808 - - 0.0000000000000000000000000000000000000000000000004641 181.0
TH2_k127_1396666_12 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000005697 173.0
TH2_k127_1396666_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000001307 169.0
TH2_k127_1396666_14 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000001616 134.0
TH2_k127_1396666_15 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000002359 141.0
TH2_k127_1396666_16 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.0000000000000000000000000001269 127.0
TH2_k127_1396666_17 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000000002715 111.0
TH2_k127_1396666_18 Pfam Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000001229 112.0
TH2_k127_1396666_19 PQQ-like domain K17760 - 1.1.9.1 0.000000000000272 78.0
TH2_k127_1396666_2 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 414.0
TH2_k127_1396666_20 OstA-like protein K09774 - - 0.00000000002488 73.0
TH2_k127_1396666_21 purine nucleotide biosynthetic process K01812,K02529,K16210 - 5.3.1.12 0.00007484 49.0
TH2_k127_1396666_22 PQQ-like domain - - - 0.0004406 49.0
TH2_k127_1396666_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 380.0
TH2_k127_1396666_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 372.0
TH2_k127_1396666_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 361.0
TH2_k127_1396666_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 352.0
TH2_k127_1396666_7 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 324.0
TH2_k127_1396666_8 isochorismatase hydrolase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 289.0
TH2_k127_1396666_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
TH2_k127_1442112_0 Protein export membrane protein K03296,K18138 - - 0.0 1037.0
TH2_k127_1442112_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.374e-205 644.0
TH2_k127_1442112_10 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000223 280.0
TH2_k127_1442112_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000008565 250.0
TH2_k127_1442112_12 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000127 179.0
TH2_k127_1442112_13 MazG-like family - - - 0.000000000000000000000000000000000000009099 150.0
TH2_k127_1442112_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 558.0
TH2_k127_1442112_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 502.0
TH2_k127_1442112_4 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 453.0
TH2_k127_1442112_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 413.0
TH2_k127_1442112_6 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 383.0
TH2_k127_1442112_7 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 342.0
TH2_k127_1442112_8 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 300.0
TH2_k127_1442112_9 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001921 282.0
TH2_k127_1445083_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1125.0
TH2_k127_1445083_1 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000002195 185.0
TH2_k127_1445083_2 - - - - 0.000000001628 68.0
TH2_k127_1555817_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 566.0
TH2_k127_1555817_1 Spermidine putrescine-binding periplasmic protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 383.0
TH2_k127_1555817_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 371.0
TH2_k127_1555817_3 ABC transporter, permease protein K02053,K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000659 271.0
TH2_k127_1555817_4 ABC transporter, permease protein K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001521 256.0
TH2_k127_1555817_5 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000001794 125.0
TH2_k127_1582608_0 PFAM Oligopeptide transporter OPT superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 465.0
TH2_k127_1582608_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 325.0
TH2_k127_1582608_2 FtsX-like permease family - - - 0.0000000000000000000000001271 114.0
TH2_k127_1639264_0 AcrB/AcrD/AcrF family - - - 0.0 1310.0
TH2_k127_1639264_1 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001618 280.0
TH2_k127_1670788_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1341.0
TH2_k127_1670788_1 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 591.0
TH2_k127_1670788_10 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000004012 241.0
TH2_k127_1670788_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000001004 229.0
TH2_k127_1670788_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000001931 213.0
TH2_k127_1670788_14 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000001331 125.0
TH2_k127_1670788_15 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000005052 117.0
TH2_k127_1670788_16 PIN domain K07063 - - 0.000000000000000000000000006465 115.0
TH2_k127_1670788_17 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000001023 111.0
TH2_k127_1670788_18 Lysin motif - - - 0.00000000000000001067 95.0
TH2_k127_1670788_2 Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 548.0
TH2_k127_1670788_3 aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 517.0
TH2_k127_1670788_4 Putative ATP-binding cassette - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 402.0
TH2_k127_1670788_5 ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 396.0
TH2_k127_1670788_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 369.0
TH2_k127_1670788_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 338.0
TH2_k127_1670788_8 Proteasomal ATPase OB/ID domain K13527 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 328.0
TH2_k127_1670788_9 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000469 287.0
TH2_k127_1689519_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1242.0
TH2_k127_1689519_1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 578.0
TH2_k127_1689519_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001236 290.0
TH2_k127_1689519_11 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003318 280.0
TH2_k127_1689519_12 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002297 270.0
TH2_k127_1689519_13 - - - - 0.00000000000000000000000000000000001886 138.0
TH2_k127_1689519_14 Belongs to the MraZ family K03925 - - 0.00000000000000000000000001325 114.0
TH2_k127_1689519_15 NlpC/P60 family - - - 0.00000000000000002006 94.0
TH2_k127_1689519_16 Protein of unknown function (DUF4236) - - - 0.00000000000000003157 85.0
TH2_k127_1689519_17 Cell division protein FtsQ K03589 - - 0.0000000000001541 81.0
TH2_k127_1689519_19 TIGRFAM YD repeat protein - - - 0.00000000002647 76.0
TH2_k127_1689519_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 465.0
TH2_k127_1689519_20 anti-sigma factor antagonist activity K11897,K21637 GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0042176,GO:0042177,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000002064 62.0
TH2_k127_1689519_21 zinc metalloprotease whose natural substrate is K06974 - - 0.000512 51.0
TH2_k127_1689519_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 423.0
TH2_k127_1689519_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 401.0
TH2_k127_1689519_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 383.0
TH2_k127_1689519_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 364.0
TH2_k127_1689519_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 350.0
TH2_k127_1689519_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 322.0
TH2_k127_1689519_9 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 309.0
TH2_k127_1711730_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 582.0
TH2_k127_1711730_2 Glyoxalase-like domain - - - 0.00000000000001301 81.0
TH2_k127_179759_0 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 449.0
TH2_k127_179759_1 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001807 289.0
TH2_k127_179759_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000593 218.0
TH2_k127_179759_3 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000002008 188.0
TH2_k127_179759_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000002556 126.0
TH2_k127_179759_5 - - - - 0.000000000000000000000000004309 119.0
TH2_k127_179759_6 - - - - 0.000000000000000000001114 102.0
TH2_k127_179759_7 Psort location Cytoplasmic, score 7.50 K01206 - 3.2.1.51 0.0000000846 56.0
TH2_k127_179759_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00006113 49.0
TH2_k127_182519_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111,K01153 - 1.1.5.3,3.1.21.3 5.39e-321 998.0
TH2_k127_182519_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 472.0
TH2_k127_182519_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000001632 105.0
TH2_k127_182519_11 Sigma-70, region 4 - - - 0.0000000000000000007556 102.0
TH2_k127_182519_12 helix_turn_helix, arabinose operon control protein - - - 0.000000000001132 72.0
TH2_k127_182519_13 - - - - 0.0000000002867 70.0
TH2_k127_182519_14 - - - - 0.000003432 60.0
TH2_k127_182519_15 Aminotransferase class-V - - - 0.0001088 51.0
TH2_k127_182519_16 ribosome binding - - - 0.0002412 49.0
TH2_k127_182519_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 407.0
TH2_k127_182519_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 401.0
TH2_k127_182519_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 347.0
TH2_k127_182519_5 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 312.0
TH2_k127_182519_6 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 312.0
TH2_k127_182519_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
TH2_k127_182519_8 - - - - 0.0000000000000000000000000000000000000000000000000000000001679 226.0
TH2_k127_182519_9 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000001069 205.0
TH2_k127_185360_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 361.0
TH2_k127_185360_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000001338 173.0
TH2_k127_185360_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000007276 64.0
TH2_k127_1856448_0 radical SAM domain protein K20444 - - 0.00000000000000000000000000000000000000000000000000000004948 215.0
TH2_k127_1856448_1 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000002571 147.0
TH2_k127_189530_0 Pyruvate kinase, alpha/beta domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 419.0
TH2_k127_189530_1 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.00000000000000000000000000000000000000000000000000000824 202.0
TH2_k127_189530_2 - - - - 0.00000000000000000000000000000000000000003414 163.0
TH2_k127_189530_3 PLD-like domain - - - 0.00000003555 61.0
TH2_k127_1924146_0 dehydrogenase, E1 component K00164 - 1.2.4.2 4.869e-287 910.0
TH2_k127_1924146_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 566.0
TH2_k127_1924146_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 522.0
TH2_k127_1924146_3 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 476.0
TH2_k127_1924146_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 475.0
TH2_k127_1924146_5 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 370.0
TH2_k127_1924146_6 - - - - 0.000000000000000000000000000000000000000000000000004572 191.0
TH2_k127_1924146_7 Glutaredoxin K07390 - - 0.0000000000000000000000000000000001971 135.0
TH2_k127_1978095_0 von Willebrand factor, type A - - - 0.0 1098.0
TH2_k127_1978095_1 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 614.0
TH2_k127_1978095_10 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000003863 171.0
TH2_k127_1978095_11 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000003245 114.0
TH2_k127_1978095_12 PFAM Plasmid stabilisation system protein K19092 - - 0.0000000000000000001179 94.0
TH2_k127_1978095_13 - - - - 0.0000000000000003231 94.0
TH2_k127_1978095_15 - - - - 0.00000527 59.0
TH2_k127_1978095_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 464.0
TH2_k127_1978095_3 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 355.0
TH2_k127_1978095_4 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 349.0
TH2_k127_1978095_5 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002195 288.0
TH2_k127_1978095_6 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 284.0
TH2_k127_1978095_7 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000002296 231.0
TH2_k127_1978095_8 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000005513 203.0
TH2_k127_1978095_9 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000336 188.0
TH2_k127_2104932_0 tryptophan synthase activity K01696,K06001 - 4.2.1.20 2.713e-215 675.0
TH2_k127_2104932_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 565.0
TH2_k127_2104932_2 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000004881 216.0
TH2_k127_2104932_3 Addiction module toxin, RelE StbE family - - - 0.00000000000000000000000000000002673 130.0
TH2_k127_2104932_4 Glycosyl transferase, family 2 - - - 0.00000000000000000000000009847 119.0
TH2_k127_2105441_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 524.0
TH2_k127_2105441_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 463.0
TH2_k127_2105441_2 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 421.0
TH2_k127_2105441_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 316.0
TH2_k127_2105441_4 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 309.0
TH2_k127_2105441_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002607 266.0
TH2_k127_2105441_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000009423 248.0
TH2_k127_2105441_7 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000000000000000000003569 190.0
TH2_k127_2267162_0 CoA-substrate-specific enzyme activase - - - 0.0 1102.0
TH2_k127_2267162_1 - - - - 0.0007437 51.0
TH2_k127_2275841_0 mannose metabolic process K01191 - 3.2.1.24 1.11e-299 954.0
TH2_k127_2275841_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 573.0
TH2_k127_2275841_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 522.0
TH2_k127_2275841_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 510.0
TH2_k127_2275841_4 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 440.0
TH2_k127_2275841_5 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 299.0
TH2_k127_2275841_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000006054 230.0
TH2_k127_2275841_7 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000001658 55.0
TH2_k127_2312648_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 537.0
TH2_k127_2312648_1 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 419.0
TH2_k127_2312648_2 - - - - 0.0000000000000000000000000000000000000000000000000007129 208.0
TH2_k127_2312648_3 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000001511 109.0
TH2_k127_2312648_4 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000001453 82.0
TH2_k127_2327557_0 sugar phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 418.0
TH2_k127_2327557_1 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 302.0
TH2_k127_2327557_2 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000001653 239.0
TH2_k127_2327557_3 Outer membrane lipoprotein K05807 - - 0.00000000000000000000000000000000000000000000000000000000000001095 228.0
TH2_k127_2327557_4 Domain of unknown function (DUF1287) K09974 - - 0.0000000000000000000000000000000000000000000000000003061 187.0
TH2_k127_2327557_5 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000001449 192.0
TH2_k127_2327557_6 Lipopolysaccharide-assembly - - - 0.000000000000000000008179 99.0
TH2_k127_2327557_7 Binds directly to 16S ribosomal RNA K02968 - - 0.00003641 51.0
TH2_k127_2342018_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 358.0
TH2_k127_2342018_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 327.0
TH2_k127_2342018_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000001425 213.0
TH2_k127_2346425_0 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.000000000000000000000000000000004799 136.0
TH2_k127_2346425_1 transmembrane transport - - - 0.00000002226 66.0
TH2_k127_2362613_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1716.0
TH2_k127_2362613_1 Belongs to the carbamoyltransferase HypF family K04656 - - 4.512e-278 879.0
TH2_k127_2362613_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 481.0
TH2_k127_2362613_3 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000004873 242.0
TH2_k127_2362613_4 carbon dioxide binding K04653 - - 0.0000000000000000000000000003087 116.0
TH2_k127_2393102_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 430.0
TH2_k127_2393102_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000003517 170.0
TH2_k127_2442875_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1172.0
TH2_k127_2442875_1 FAD dependent oxidoreductase - - - 9.919e-234 736.0
TH2_k127_2442875_10 dioxygenase activity K18565 - - 0.000000000000000000000000000000000000000000000006023 186.0
TH2_k127_2442875_11 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000000000001856 177.0
TH2_k127_2442875_12 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000001377 174.0
TH2_k127_2442875_13 Glycosyl transferase, family 2 K01002,K20534 - 2.7.8.20 0.0000000000000000000000000000000000001117 158.0
TH2_k127_2442875_14 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000001673 138.0
TH2_k127_2442875_15 transcriptional regulator (AraC family) - - - 0.000000000000000007413 94.0
TH2_k127_2442875_16 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000001755 89.0
TH2_k127_2442875_17 - - - - 0.00000004023 61.0
TH2_k127_2442875_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.079e-224 714.0
TH2_k127_2442875_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 584.0
TH2_k127_2442875_4 DNA photolyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 510.0
TH2_k127_2442875_5 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 496.0
TH2_k127_2442875_6 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 311.0
TH2_k127_2442875_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000642 292.0
TH2_k127_2442875_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000004197 217.0
TH2_k127_2442875_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000005122 194.0
TH2_k127_2442968_0 Fibronectin type 3 domain - - - 1.128e-254 832.0
TH2_k127_2442968_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.169e-206 661.0
TH2_k127_2442968_10 Thiol disulfide interchange protein - - - 0.0000000000000000001808 93.0
TH2_k127_2442968_2 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 457.0
TH2_k127_2442968_3 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 449.0
TH2_k127_2442968_4 reverse transcriptase K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 436.0
TH2_k127_2442968_5 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009492 331.0
TH2_k127_2442968_6 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008543 258.0
TH2_k127_2442968_7 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000000000000000000001091 231.0
TH2_k127_2442968_8 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000008413 175.0
TH2_k127_2442968_9 protein-disulfide reductase activity K05807 - - 0.00000000000000000001979 96.0
TH2_k127_2472341_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1244.0
TH2_k127_2472341_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 2.602e-218 686.0
TH2_k127_2472341_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 481.0
TH2_k127_2472341_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 415.0
TH2_k127_2472341_4 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005196 287.0
TH2_k127_2472341_5 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000001763 239.0
TH2_k127_2472341_6 nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000000000000000000001545 185.0
TH2_k127_2487355_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 356.0
TH2_k127_2487355_1 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 347.0
TH2_k127_2487355_10 Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000004243 206.0
TH2_k127_2487355_11 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000008821 191.0
TH2_k127_2487355_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000002107 181.0
TH2_k127_2487355_13 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000002741 96.0
TH2_k127_2487355_14 Putative zinc-finger - - - 0.00001253 55.0
TH2_k127_2487355_15 - - - - 0.00002216 53.0
TH2_k127_2487355_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 323.0
TH2_k127_2487355_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 323.0
TH2_k127_2487355_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009747 270.0
TH2_k127_2487355_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000822 269.0
TH2_k127_2487355_6 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006762 246.0
TH2_k127_2487355_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000505 235.0
TH2_k127_2487355_8 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000002089 239.0
TH2_k127_2487355_9 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000000000000000001048 218.0
TH2_k127_2513945_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 5.577e-235 751.0
TH2_k127_2513945_1 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 609.0
TH2_k127_2513945_2 TIGRFAM oligoendopeptidase, M3 family K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 537.0
TH2_k127_2513945_3 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 452.0
TH2_k127_2513945_4 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 404.0
TH2_k127_2513945_5 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 348.0
TH2_k127_2513945_6 - - - - 0.00000000000000000000000001377 115.0
TH2_k127_2513945_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000007413 118.0
TH2_k127_2513945_8 phosphorylase K01243 - 3.2.2.9 0.00000000000000000002891 100.0
TH2_k127_251779_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 376.0
TH2_k127_251779_1 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000002347 195.0
TH2_k127_2584062_0 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 445.0
TH2_k127_2584062_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 358.0
TH2_k127_2584062_10 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0001648 50.0
TH2_k127_2584062_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 325.0
TH2_k127_2584062_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 321.0
TH2_k127_2584062_4 Methyltransferase domain K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004517 257.0
TH2_k127_2584062_5 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000009838 179.0
TH2_k127_2584062_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000004305 115.0
TH2_k127_2584062_7 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.00000000000000000002072 108.0
TH2_k127_2584062_8 nuclear chromosome segregation - - - 0.0000004563 64.0
TH2_k127_2584062_9 domain, Protein - - - 0.000001396 62.0
TH2_k127_2591304_0 Predicted Permease Membrane Region K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 576.0
TH2_k127_2591304_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000002426 141.0
TH2_k127_2591304_2 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.000000000000000000000005449 105.0
TH2_k127_2591304_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000002807 57.0
TH2_k127_2591304_4 Tellurite resistance protein TerB - - - 0.0001434 54.0
TH2_k127_2596082_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.273e-207 657.0
TH2_k127_2596082_1 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 530.0
TH2_k127_2596082_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 412.0
TH2_k127_2596082_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001864 258.0
TH2_k127_2596082_4 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000002548 205.0
TH2_k127_2596082_5 PFAM peptidase S16 lon domain protein K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000007681 173.0
TH2_k127_2596082_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000001517 153.0
TH2_k127_2596082_7 Transposase - - - 0.00000000000000000000000000165 115.0
TH2_k127_2596082_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000139 53.0
TH2_k127_2623477_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003519 303.0
TH2_k127_2623477_1 - - - - 0.0000000000000000000000000001408 134.0
TH2_k127_2623477_2 COG1388 FOG LysM repeat K19223,K19224,K21471 - - 0.0001112 57.0
TH2_k127_2628817_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.461e-198 629.0
TH2_k127_2628817_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 397.0
TH2_k127_2628817_2 Belongs to the 'phage' integrase family - - - 0.0000000007886 59.0
TH2_k127_2643089_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1197.0
TH2_k127_2643089_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 379.0
TH2_k127_2643089_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001662 228.0
TH2_k127_2643089_3 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000005167 200.0
TH2_k127_2643089_4 long-chain fatty acid transporting porin activity K06076 - - 0.0000000001129 65.0
TH2_k127_27371_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1135.0
TH2_k127_27371_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.309e-319 1002.0
TH2_k127_27371_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000002816 186.0
TH2_k127_27371_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000001599 149.0
TH2_k127_27371_4 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000115 147.0
TH2_k127_27371_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000001044 138.0
TH2_k127_27371_6 response regulator K07657 - - 0.000000000000004661 80.0
TH2_k127_27371_7 histone H2A K63-linked ubiquitination - - - 0.0000000007877 70.0
TH2_k127_27371_8 4-amino-4-deoxy-L-arabinose transferase - - - 0.0008473 52.0
TH2_k127_2748294_0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 359.0
TH2_k127_2748294_1 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000000009096 139.0
TH2_k127_2748294_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine - - - 0.000000000000000001759 98.0
TH2_k127_2748294_3 Alpha-2-macroglobulin family - - - 0.00000004357 61.0
TH2_k127_2757905_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000003171 254.0
TH2_k127_283152_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.408e-218 694.0
TH2_k127_283152_1 Putative regulatory protein - - - 0.0000000000000000000000000007666 115.0
TH2_k127_283152_2 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 0.0001317 49.0
TH2_k127_2834904_0 Iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 464.0
TH2_k127_2834904_1 hydrolase, family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 309.0
TH2_k127_2834904_2 helicase superfamily c-terminal domain K07012 - - 0.000000000000000000000000000000000000000000000000000000000000000000127 234.0
TH2_k127_2834904_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000005172 215.0
TH2_k127_2834904_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000001022 203.0
TH2_k127_28525_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.17e-321 993.0
TH2_k127_28525_1 enzyme of the MoaA nifB pqqE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 542.0
TH2_k127_28525_10 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000636 141.0
TH2_k127_28525_11 3-dehydroquinate dehydratase activity K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.0000000000000000000000000000188 126.0
TH2_k127_28525_12 sequence-specific DNA binding - - - 0.000000000000000000000000000152 127.0
TH2_k127_28525_13 Belongs to the glycosyl hydrolase 3 family K01207 - 3.2.1.52 0.000000000000000000000001154 106.0
TH2_k127_28525_14 - - - - 0.0000000000000001237 80.0
TH2_k127_28525_15 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000317 65.0
TH2_k127_28525_17 - - - - 0.000001888 50.0
TH2_k127_28525_2 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 517.0
TH2_k127_28525_3 dioxygenase activity K00477,K18565 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 342.0
TH2_k127_28525_4 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 333.0
TH2_k127_28525_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000007819 260.0
TH2_k127_28525_6 - - - - 0.0000000000000000000000000000000000000000000000000003213 188.0
TH2_k127_28525_7 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000000000007413 199.0
TH2_k127_28525_8 - - - - 0.0000000000000000000000000000000000000001367 156.0
TH2_k127_28525_9 - - - - 0.00000000000000000000000000000000000000534 148.0
TH2_k127_286907_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.29e-213 681.0
TH2_k127_286907_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 573.0
TH2_k127_286907_10 HIRAN - - - 0.00000000000000000000008735 102.0
TH2_k127_286907_11 - - - - 0.0000000000000000000001589 99.0
TH2_k127_286907_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 563.0
TH2_k127_286907_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 475.0
TH2_k127_286907_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 452.0
TH2_k127_286907_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000002667 220.0
TH2_k127_286907_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000009084 204.0
TH2_k127_286907_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000009402 206.0
TH2_k127_286907_8 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000009949 197.0
TH2_k127_286907_9 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000001177 129.0
TH2_k127_292864_0 EcoEI R protein C-terminal K01153 - 3.1.21.3 1.27e-321 1002.0
TH2_k127_292864_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 401.0
TH2_k127_292864_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 318.0
TH2_k127_292864_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003667 268.0
TH2_k127_292864_4 HAD-hyrolase-like K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000008448 264.0
TH2_k127_292864_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000003849 207.0
TH2_k127_292864_6 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000001352 169.0
TH2_k127_292864_7 Putative RNA methylase family UPF0020 K03427 - 2.1.1.72 0.0000000000000000000000000003797 117.0
TH2_k127_292864_8 - - - - 0.000001734 56.0
TH2_k127_292864_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000135 59.0
TH2_k127_2947324_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 8.107e-211 669.0
TH2_k127_2947324_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 336.0
TH2_k127_2947324_10 Ribosomal protein S21 K02970 - - 0.000000000001409 69.0
TH2_k127_2947324_11 membrane K05794 - - 0.00000000001512 67.0
TH2_k127_2947324_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
TH2_k127_2947324_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001866 265.0
TH2_k127_2947324_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001562 250.0
TH2_k127_2947324_5 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000000000000000000000000000002529 212.0
TH2_k127_2947324_6 SCO1/SenC - - - 0.00000000000000000000000000000000000000000000000008099 193.0
TH2_k127_2947324_7 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000004168 186.0
TH2_k127_2947324_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000265 145.0
TH2_k127_2947324_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000007374 135.0
TH2_k127_301978_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 4.988e-202 654.0
TH2_k127_301978_1 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 529.0
TH2_k127_301978_10 competence protein - - - 0.000000000000000000000000000000000000000000002608 179.0
TH2_k127_301978_11 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000003196 153.0
TH2_k127_301978_12 protein secretion K02460 - - 0.000000000000000000000000000000006033 144.0
TH2_k127_301978_13 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000005808 115.0
TH2_k127_301978_14 - - - - 0.000000000000000006384 89.0
TH2_k127_301978_15 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.000000000000004682 79.0
TH2_k127_301978_16 Transmembrane proteins 14C - - - 0.000000000000007783 78.0
TH2_k127_301978_17 CAAX protease self-immunity - - - 0.0000000000007176 79.0
TH2_k127_301978_18 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000002388 70.0
TH2_k127_301978_19 - K02457 - - 0.000006607 56.0
TH2_k127_301978_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 358.0
TH2_k127_301978_20 Prokaryotic N-terminal methylation motif K02459 - - 0.00004963 54.0
TH2_k127_301978_21 carbon utilization K02664 - - 0.00005266 52.0
TH2_k127_301978_3 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 362.0
TH2_k127_301978_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 356.0
TH2_k127_301978_5 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 297.0
TH2_k127_301978_6 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 296.0
TH2_k127_301978_7 Bacterial type II/III secretion system short domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002291 306.0
TH2_k127_301978_8 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000005385 267.0
TH2_k127_301978_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000535 236.0
TH2_k127_3029545_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1274.0
TH2_k127_3029545_1 Transposase IS200 like - - - 0.0000000000000000004713 88.0
TH2_k127_315640_0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 606.0
TH2_k127_315640_1 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 500.0
TH2_k127_315640_10 PFAM TM2 domain - - - 0.00000000000000000000000009661 114.0
TH2_k127_315640_11 Tetratricopeptide repeat - - - 0.0000000000000000000000004136 119.0
TH2_k127_315640_12 Protein of unknown function (DUF2752) - - - 0.000000000000000000000004696 108.0
TH2_k127_315640_13 cheY-homologous receiver domain - - - 0.000000000000000000003552 96.0
TH2_k127_315640_14 response to antibiotic - - - 0.000000000000000002464 92.0
TH2_k127_315640_15 Transposase IS4 family protein - - - 0.00000000000003315 80.0
TH2_k127_315640_16 RDD family K18481 - - 0.00000000003299 71.0
TH2_k127_315640_17 transposase activity - - - 0.00000002662 59.0
TH2_k127_315640_18 RDD family K18481 - - 0.0000007594 58.0
TH2_k127_315640_19 RDD family K18481 - - 0.000003319 56.0
TH2_k127_315640_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 346.0
TH2_k127_315640_20 Domain of unknown function (DUF4190) - - - 0.00003742 53.0
TH2_k127_315640_21 PQQ-like domain - - - 0.00005526 58.0
TH2_k127_315640_22 - - - - 0.00009571 57.0
TH2_k127_315640_3 Patatin-like phospholipase K02282,K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000001183 258.0
TH2_k127_315640_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000001245 219.0
TH2_k127_315640_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000001208 201.0
TH2_k127_315640_6 Ferritin-like domain K02217,K22336 - 1.16.3.1,1.16.3.2 0.00000000000000000000000000000000000000000000001032 176.0
TH2_k127_315640_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000005348 177.0
TH2_k127_315640_8 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000003448 169.0
TH2_k127_315640_9 TM2 domain - - - 0.000000000000000000000000000004649 122.0
TH2_k127_3197602_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000001508 235.0
TH2_k127_3197602_1 haloacid dehalogenase-like hydrolase K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000000000000000000007356 121.0
TH2_k127_3197602_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000002726 66.0
TH2_k127_3214632_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000004533 238.0
TH2_k127_3214632_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000009119 163.0
TH2_k127_3271579_0 COG1894 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335,K18331 - 1.12.1.3,1.6.5.3 1.636e-279 891.0
TH2_k127_3271579_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 479.0
TH2_k127_3271579_2 PQQ-like domain K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 436.0
TH2_k127_3271579_3 FMN-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 387.0
TH2_k127_3271579_4 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 367.0
TH2_k127_3271579_5 - K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002172 260.0
TH2_k127_3271579_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000007395 186.0
TH2_k127_3271579_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000003681 160.0
TH2_k127_329705_0 Pup-ligase protein K20814 - 3.5.1.119 2.203e-194 620.0
TH2_k127_329705_1 Pup-ligase protein K13571 - 6.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 571.0
TH2_k127_329705_2 Proteasomal ATPase OB/ID domain K13527 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 478.0
TH2_k127_329705_3 Proteasome subunit K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
TH2_k127_329705_4 Proteasome subunit K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000006862 219.0
TH2_k127_329705_5 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000003901 163.0
TH2_k127_329705_6 Alternative locus ID K10697 - - 0.000000000000000000000006866 106.0
TH2_k127_329705_7 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.0000000000000003914 79.0
TH2_k127_3354510_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 462.0
TH2_k127_3354510_1 iron dependent repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 421.0
TH2_k127_3354510_2 domain, Protein K08961 - 4.2.2.20,4.2.2.21 0.00004878 52.0
TH2_k127_3364630_0 PFAM Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 491.0
TH2_k127_3364630_1 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 475.0
TH2_k127_3364630_2 Protein of unknown function (DUF3419) K13622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 441.0
TH2_k127_3364630_3 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K22319 - 6.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 445.0
TH2_k127_3364630_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 331.0
TH2_k127_3364630_5 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 305.0
TH2_k127_3364630_6 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000002913 102.0
TH2_k127_3370754_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 544.0
TH2_k127_3370754_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 401.0
TH2_k127_3370754_10 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000001505 83.0
TH2_k127_3370754_11 Drug metabolite transporter - - - 0.0000000835 63.0
TH2_k127_3370754_12 Prokaryotic N-terminal methylation motif - - - 0.0001659 51.0
TH2_k127_3370754_13 Glycine zipper - - - 0.0009721 46.0
TH2_k127_3370754_2 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 340.0
TH2_k127_3370754_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002138 249.0
TH2_k127_3370754_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000001353 233.0
TH2_k127_3370754_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000003752 209.0
TH2_k127_3370754_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000006959 179.0
TH2_k127_3370754_7 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000000001435 175.0
TH2_k127_3370754_8 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000003245 115.0
TH2_k127_3370754_9 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000004862 87.0
TH2_k127_3378641_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 8.575e-211 674.0
TH2_k127_3378641_1 PFAM FIST C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 328.0
TH2_k127_3378641_10 protein kinase activity - - - 0.00000008195 67.0
TH2_k127_3378641_11 Tetratricopeptide repeat - - - 0.0000002797 63.0
TH2_k127_3378641_12 amine dehydrogenase activity K03496,K05592 - 3.6.4.13 0.00000903 59.0
TH2_k127_3378641_15 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0001561 44.0
TH2_k127_3378641_2 Conserved protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 326.0
TH2_k127_3378641_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 306.0
TH2_k127_3378641_4 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001609 286.0
TH2_k127_3378641_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003521 239.0
TH2_k127_3378641_6 Cadherin repeats. - - - 0.000000000000000000000000000000000000000000000000000000000000000003108 259.0
TH2_k127_3378641_7 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000008463 152.0
TH2_k127_3378641_8 Domain of unknown function DUF11 - - - 0.000000000000000000000008098 120.0
TH2_k127_3384581_0 Transposase DDE domain - - - 1.863e-200 639.0
TH2_k127_3384581_1 Ricin-type beta-trefoil - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 432.0
TH2_k127_3387684_0 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005477 254.0
TH2_k127_3392533_0 - - - - 0.00000002015 68.0
TH2_k127_3401042_0 A-macroglobulin receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 553.0
TH2_k127_3401042_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000001299 126.0
TH2_k127_3409760_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.127e-295 929.0
TH2_k127_3409760_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.818e-202 640.0
TH2_k127_3409760_10 PFAM Stage II sporulation E family protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 394.0
TH2_k127_3409760_11 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 386.0
TH2_k127_3409760_12 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 337.0
TH2_k127_3409760_13 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 331.0
TH2_k127_3409760_14 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 309.0
TH2_k127_3409760_15 Cell cycle protein K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 305.0
TH2_k127_3409760_16 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 295.0
TH2_k127_3409760_17 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K18824 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 292.0
TH2_k127_3409760_18 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 283.0
TH2_k127_3409760_19 PFAM TatD-related deoxyribonuclease K07051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 287.0
TH2_k127_3409760_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.682e-200 631.0
TH2_k127_3409760_20 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001982 287.0
TH2_k127_3409760_21 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008375 269.0
TH2_k127_3409760_22 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000002972 263.0
TH2_k127_3409760_23 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000001029 250.0
TH2_k127_3409760_24 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000126 252.0
TH2_k127_3409760_25 DisA bacterial checkpoint controller nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000001617 222.0
TH2_k127_3409760_26 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000003944 209.0
TH2_k127_3409760_27 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000004192 190.0
TH2_k127_3409760_28 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000002353 179.0
TH2_k127_3409760_29 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000002091 164.0
TH2_k127_3409760_3 Ribonuclease E/G family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 579.0
TH2_k127_3409760_30 MoaC family K03637 - 4.6.1.17 0.00000000000000000000000000000000000003088 150.0
TH2_k127_3409760_31 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000009521 159.0
TH2_k127_3409760_32 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.000000000000000000000000000000000002178 147.0
TH2_k127_3409760_33 Domain of unknown function (DUF1802) - - - 0.000000000000000000000000000000000004354 145.0
TH2_k127_3409760_34 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000003923 136.0
TH2_k127_3409760_35 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000000000003861 128.0
TH2_k127_3409760_36 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000004027 128.0
TH2_k127_3409760_37 Protein of unknown function (DUF971) - - - 0.000000000000000000000002243 106.0
TH2_k127_3409760_38 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000008076 96.0
TH2_k127_3409760_39 Transposase is116 is110 is902 family - - - 0.00000000000000003043 85.0
TH2_k127_3409760_4 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 523.0
TH2_k127_3409760_40 response regulator K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.00000000000000003534 87.0
TH2_k127_3409760_41 ABC transporter K02065 - - 0.00000000000000004678 91.0
TH2_k127_3409760_42 histidine kinase A domain protein - - - 0.00000000000000004779 86.0
TH2_k127_3409760_43 - - - - 0.000000000000000163 90.0
TH2_k127_3409760_44 YbbR-like protein - - - 0.0000000000000007168 89.0
TH2_k127_3409760_45 ThiS family K03636 - - 0.000000000000001783 81.0
TH2_k127_3409760_46 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000002993 81.0
TH2_k127_3409760_47 hyperosmotic response K04065 - - 0.0000000000009361 75.0
TH2_k127_3409760_48 FHA domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000003281 69.0
TH2_k127_3409760_49 O-antigen ligase - - - 0.00000000005276 76.0
TH2_k127_3409760_5 COG1064 Zn-dependent alcohol K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 510.0
TH2_k127_3409760_50 - - - - 0.0000000005772 64.0
TH2_k127_3409760_51 - - - - 0.000000000631 64.0
TH2_k127_3409760_52 PFAM Amino acid-binding ACT - - - 0.000000003374 64.0
TH2_k127_3409760_53 Septum formation initiator - - - 0.000001979 56.0
TH2_k127_3409760_54 Protein of unknown function (DUF2934) - - - 0.0006339 46.0
TH2_k127_3409760_55 - - - - 0.0008582 48.0
TH2_k127_3409760_56 Protein involved in outer membrane biogenesis K07289,K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0008778 50.0
TH2_k127_3409760_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 477.0
TH2_k127_3409760_7 HMGL-like K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 445.0
TH2_k127_3409760_8 Peptidase, M16 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 414.0
TH2_k127_3409760_9 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 402.0
TH2_k127_3437996_0 Nitroreductase family K19286 - 1.5.1.39 0.00000001362 64.0
TH2_k127_3437996_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000007989 58.0
TH2_k127_3440470_0 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000000000000000000000000000000000000000000000000000000002758 241.0
TH2_k127_3440470_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
TH2_k127_3440470_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000002259 198.0
TH2_k127_3440470_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000007772 182.0
TH2_k127_3440470_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000004215 117.0
TH2_k127_3440470_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000004717 110.0
TH2_k127_3440470_6 phosphorelay signal transduction system K02481 - - 0.0000000000000000000003369 101.0
TH2_k127_3440470_7 PFAM Fibronectin type III domain - - - 0.000000000000000000001593 111.0
TH2_k127_3440470_8 - - - - 0.0000001054 55.0
TH2_k127_3440470_9 membrane protein domain - - - 0.00002678 49.0
TH2_k127_3501633_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 2.772e-195 622.0
TH2_k127_3501633_1 Glycosyl hydrolase family 63 C-terminal domain - - - 2.997e-194 618.0
TH2_k127_3501633_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 615.0
TH2_k127_3501633_3 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 368.0
TH2_k127_3501633_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001157 282.0
TH2_k127_3501633_5 Polymer-forming cytoskeletal - - - 0.000003435 55.0
TH2_k127_3501633_6 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000003833 55.0
TH2_k127_3514617_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 338.0
TH2_k127_3514617_1 PFAM Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000015 274.0
TH2_k127_3514617_2 SMART phosphoesterase PHP domain protein - - - 0.0000000000000004212 90.0
TH2_k127_3522199_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 597.0
TH2_k127_3522199_1 receptor K16091 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0008324,GO:0009279,GO:0015075,GO:0015091,GO:0015318,GO:0015682,GO:0016020,GO:0019867,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030313,GO:0031975,GO:0034220,GO:0034755,GO:0044462,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072510,GO:0072512,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 506.0
TH2_k127_3522199_10 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000001645 60.0
TH2_k127_3522199_11 COG1918 Fe2 transport system protein A K04758 - - 0.000004376 52.0
TH2_k127_3522199_12 Ferritin-like domain K03594 - 1.16.3.1 0.0005507 48.0
TH2_k127_3522199_2 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000001895 241.0
TH2_k127_3522199_3 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000002413 201.0
TH2_k127_3522199_4 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000002559 187.0
TH2_k127_3522199_5 MotA TolQ ExbB proton channel - - - 0.0000000000000000000000000000000000000006487 156.0
TH2_k127_3522199_6 Competence-damaged protein K03742 - 3.5.1.42 0.0000000000000000000000000000000000002045 145.0
TH2_k127_3522199_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000001841 129.0
TH2_k127_3522199_8 protein, ExbD TolR family K03559 - - 0.000000000000002671 83.0
TH2_k127_3522199_9 Iron dependent repressor DNA binding domain protein - - - 0.00000000008721 70.0
TH2_k127_3528656_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 337.0
TH2_k127_3531007_0 Belongs to the glycosyl hydrolase 57 family - - - 7.338e-317 989.0
TH2_k127_3531007_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 534.0
TH2_k127_3531007_10 diguanylate cyclase - - - 0.00000000000003842 84.0
TH2_k127_3531007_11 COG2963 Transposase and inactivated derivatives K07483 - - 0.0000001994 61.0
TH2_k127_3531007_12 COG0471 Di- and tricarboxylate transporters - - - 0.0000004748 56.0
TH2_k127_3531007_13 tRNA_anti-like - - - 0.00006767 49.0
TH2_k127_3531007_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 407.0
TH2_k127_3531007_3 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 403.0
TH2_k127_3531007_4 IS66 C-terminal element - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
TH2_k127_3531007_5 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000003933 215.0
TH2_k127_3531007_6 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000000000697 144.0
TH2_k127_3531007_7 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000000000000000000000000000004488 138.0
TH2_k127_3531007_8 Transcriptional regulator - - - 0.00000000000000002653 83.0
TH2_k127_3531007_9 HTH-like domain K07497 - - 0.0000000000000003234 83.0
TH2_k127_3534642_0 Elongation factor G C-terminus K06207 - - 6.757e-266 834.0
TH2_k127_3534642_1 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 603.0
TH2_k127_3534642_11 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000185 55.0
TH2_k127_3534642_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 314.0
TH2_k127_3534642_3 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 308.0
TH2_k127_3534642_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K02849,K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009203 262.0
TH2_k127_3534642_5 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000003961 161.0
TH2_k127_3534642_6 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000222 148.0
TH2_k127_3534642_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000001469 125.0
TH2_k127_3534642_8 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000007265 86.0
TH2_k127_3534642_9 nuclear chromosome segregation - - - 0.000000009872 66.0
TH2_k127_3534783_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 616.0
TH2_k127_3534783_1 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 569.0
TH2_k127_3534783_10 proteolysis - - - 0.00000000000000000000000000000002252 134.0
TH2_k127_3534783_11 Peptidase_C39 like family - - - 0.000000000000000000001972 108.0
TH2_k127_3534783_12 Metallophosphoesterase K01090 - 3.1.3.16 0.0000000000000000003671 98.0
TH2_k127_3534783_13 DoxX K16937 - 1.8.5.2 0.000000000000003027 81.0
TH2_k127_3534783_14 Protein of unknown function (DUF721) - - - 0.000000000008137 74.0
TH2_k127_3534783_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 547.0
TH2_k127_3534783_3 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 412.0
TH2_k127_3534783_4 Cysteine synthase B K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 368.0
TH2_k127_3534783_5 PFAM Glycosyltransferase family 28 C-terminal domain K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000001351 244.0
TH2_k127_3534783_6 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000009614 222.0
TH2_k127_3534783_7 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000772 211.0
TH2_k127_3534783_8 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000905 171.0
TH2_k127_3534783_9 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000000000000000000004375 133.0
TH2_k127_354816_0 Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers K06955 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002733 264.0
TH2_k127_3555019_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 493.0
TH2_k127_3555019_1 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005047 245.0
TH2_k127_3555019_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000001024 129.0
TH2_k127_3592396_0 - - - - 0.000000000000000000000000000000000000000000000000007937 197.0
TH2_k127_3592396_1 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000005879 177.0
TH2_k127_3592396_2 - - - - 0.00000000000000000000000005545 115.0
TH2_k127_3680415_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 402.0
TH2_k127_3680415_1 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 308.0
TH2_k127_3680415_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000002696 241.0
TH2_k127_3680415_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000006291 243.0
TH2_k127_3680415_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000001081 226.0
TH2_k127_3680415_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000003533 115.0
TH2_k127_3680415_6 Domain of unknown function (DUF4190) - - - 0.000000000005333 74.0
TH2_k127_3680415_7 - - - - 0.00001025 51.0
TH2_k127_3680415_8 Peptidase, M28 - - - 0.0002028 52.0
TH2_k127_3680415_9 HTH domain - - - 0.0009687 42.0
TH2_k127_3708937_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.863e-245 790.0
TH2_k127_3708937_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 600.0
TH2_k127_3708937_10 Phage regulatory protein - - - 0.0000000000000000000005841 100.0
TH2_k127_3708937_14 - - - - 0.00000000007315 63.0
TH2_k127_3708937_15 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K09968 - - 0.00003744 48.0
TH2_k127_3708937_16 - - - - 0.00004849 48.0
TH2_k127_3708937_17 - - - - 0.0006682 47.0
TH2_k127_3708937_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 522.0
TH2_k127_3708937_3 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 458.0
TH2_k127_3708937_4 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 436.0
TH2_k127_3708937_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 414.0
TH2_k127_3708937_6 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000653 224.0
TH2_k127_3708937_7 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000005036 207.0
TH2_k127_3708937_8 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000006123 160.0
TH2_k127_3708937_9 - - - - 0.0000000000000000000001256 99.0
TH2_k127_381280_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 540.0
TH2_k127_381280_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 399.0
TH2_k127_381280_2 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 362.0
TH2_k127_381280_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000014 316.0
TH2_k127_381280_4 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005951 249.0
TH2_k127_381280_5 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000000000003519 139.0
TH2_k127_381280_6 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000006845 74.0
TH2_k127_381280_7 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0002298 44.0
TH2_k127_38157_0 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 507.0
TH2_k127_38157_1 Chromate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 491.0
TH2_k127_38157_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 297.0
TH2_k127_38157_3 Ribosomal small subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 296.0
TH2_k127_38157_4 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001486 264.0
TH2_k127_38157_5 Low molecular weight phosphatase family - - - 0.000000000000000000000000000000000000000000000001542 177.0
TH2_k127_38157_6 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000003377 107.0
TH2_k127_38157_7 - - - - 0.0000000000001404 72.0
TH2_k127_3824233_0 - - - - 0.0001261 51.0
TH2_k127_3832985_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1086.0
TH2_k127_3832985_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.156e-310 962.0
TH2_k127_3832985_10 alkaline phosphatase activity K01077,K01126 - 3.1.3.1,3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 480.0
TH2_k127_3832985_11 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 472.0
TH2_k127_3832985_12 galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 471.0
TH2_k127_3832985_13 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 465.0
TH2_k127_3832985_14 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 468.0
TH2_k127_3832985_15 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 434.0
TH2_k127_3832985_16 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 430.0
TH2_k127_3832985_17 Dehydrogenase E1 component K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 436.0
TH2_k127_3832985_18 electron transfer activity K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 404.0
TH2_k127_3832985_19 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 406.0
TH2_k127_3832985_2 oxidoreductase K00311,K00313 - 1.5.5.1 1.921e-285 889.0
TH2_k127_3832985_20 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 393.0
TH2_k127_3832985_21 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 393.0
TH2_k127_3832985_22 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 394.0
TH2_k127_3832985_23 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 317.0
TH2_k127_3832985_24 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 308.0
TH2_k127_3832985_25 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000004781 267.0
TH2_k127_3832985_26 Xylose isomerase K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007682 259.0
TH2_k127_3832985_27 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000002169 237.0
TH2_k127_3832985_28 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000003183 239.0
TH2_k127_3832985_29 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000003561 245.0
TH2_k127_3832985_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.269e-197 637.0
TH2_k127_3832985_30 Flavoprotein K01598 - 4.1.1.36 0.00000000000000000000000000000000000000000000000000000000000009157 218.0
TH2_k127_3832985_31 4Fe-4S binding domain K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000002599 224.0
TH2_k127_3832985_32 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000811 207.0
TH2_k127_3832985_33 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000005937 204.0
TH2_k127_3832985_34 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000002561 197.0
TH2_k127_3832985_35 Phage regulatory protein - - - 0.00000000000000000000000000000000000000000000001215 193.0
TH2_k127_3832985_36 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000001514 177.0
TH2_k127_3832985_37 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000001899 175.0
TH2_k127_3832985_38 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000007188 159.0
TH2_k127_3832985_39 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000001093 153.0
TH2_k127_3832985_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 550.0
TH2_k127_3832985_40 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000009297 144.0
TH2_k127_3832985_41 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.0000000000000000000000000000000002419 143.0
TH2_k127_3832985_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000001739 134.0
TH2_k127_3832985_44 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000003328 110.0
TH2_k127_3832985_45 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000005505 113.0
TH2_k127_3832985_46 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000008376 107.0
TH2_k127_3832985_47 deoxyhypusine monooxygenase activity - - - 0.0000002807 63.0
TH2_k127_3832985_48 Histidine kinase K05962 - 2.7.13.1 0.0000386 51.0
TH2_k127_3832985_5 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 536.0
TH2_k127_3832985_6 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 558.0
TH2_k127_3832985_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 528.0
TH2_k127_3832985_8 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 482.0
TH2_k127_3832985_9 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 486.0
TH2_k127_3849060_0 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001647 264.0
TH2_k127_3849060_1 Bacterial export proteins, family 1 K02421 - - 0.0000000000000000000002867 107.0
TH2_k127_3849060_2 PFAM surface presentation of antigens (SPOA) K02417 - - 0.00000000000000000008614 91.0
TH2_k127_3849060_3 Role in flagellar biosynthesis K02420 - - 0.00000000000000003544 83.0
TH2_k127_3849060_4 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416,K02417 - - 0.000000001412 64.0
TH2_k127_3849060_5 flagellar K02418 - - 0.00003207 54.0
TH2_k127_3866682_0 - - - - 0.000000000000000000000000000000000000001646 171.0
TH2_k127_387080_0 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 586.0
TH2_k127_387080_1 Pfam:HipA_N K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003907 265.0
TH2_k127_387080_2 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000007031 246.0
TH2_k127_387080_3 RNA-binding protein - - - 0.0000000000000000000000000000003768 126.0
TH2_k127_387080_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000004652 119.0
TH2_k127_387080_5 HipA N-terminal domain - - - 0.000000000000000000000003807 107.0
TH2_k127_387080_6 transcriptional regulator - - - 0.0000000000000002153 81.0
TH2_k127_387080_7 Heparinase II/III-like protein - - - 0.0000000000007225 83.0
TH2_k127_3903888_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 2.826e-222 698.0
TH2_k127_3903888_1 Protein of unknown function (DUF1501) - - - 4.938e-200 632.0
TH2_k127_3903888_10 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000004881 166.0
TH2_k127_3903888_11 SMART metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000009743 175.0
TH2_k127_3903888_12 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000002416 167.0
TH2_k127_3903888_13 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000009371 117.0
TH2_k127_3903888_14 Cytidylate kinase-like family - - - 0.000000000000000000000000001427 121.0
TH2_k127_3903888_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000001861 109.0
TH2_k127_3903888_16 Belongs to the bacterial flagellin family K02397 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000002701 102.0
TH2_k127_3903888_17 - - - - 0.00000000000000000003572 96.0
TH2_k127_3903888_18 FlgN protein - - - 0.00000000006492 72.0
TH2_k127_3903888_19 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000008532 63.0
TH2_k127_3903888_2 domain, Protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 595.0
TH2_k127_3903888_20 restriction endodeoxyribonuclease activity - - - 0.000000000533 66.0
TH2_k127_3903888_21 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000004741 66.0
TH2_k127_3903888_22 Rod binding protein K02395 - - 0.000002542 57.0
TH2_k127_3903888_3 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 503.0
TH2_k127_3903888_4 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 482.0
TH2_k127_3903888_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 402.0
TH2_k127_3903888_6 Flagella basal body rod protein K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 334.0
TH2_k127_3903888_7 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000001642 250.0
TH2_k127_3903888_8 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000001178 220.0
TH2_k127_3903888_9 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000006972 209.0
TH2_k127_3917504_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 347.0
TH2_k127_3917504_1 PFAM Mammalian cell entry related domain protein K02067 - - 0.0001759 53.0
TH2_k127_3940169_0 SMART Elongator protein 3 MiaB NifB - - - 1.742e-230 729.0
TH2_k127_3940169_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 389.0
TH2_k127_3940169_2 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000004101 186.0
TH2_k127_3940169_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000001227 59.0
TH2_k127_3946276_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2064.0
TH2_k127_3946276_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.0 1691.0
TH2_k127_3946276_10 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 314.0
TH2_k127_3946276_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 288.0
TH2_k127_3946276_12 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 287.0
TH2_k127_3946276_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009563 256.0
TH2_k127_3946276_14 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000001728 250.0
TH2_k127_3946276_15 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000001584 239.0
TH2_k127_3946276_16 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000278 222.0
TH2_k127_3946276_17 RNase_H superfamily K06877 - - 0.000000000000000000000000000000000000000000000000000000000000001301 222.0
TH2_k127_3946276_18 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000041 222.0
TH2_k127_3946276_19 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000001369 214.0
TH2_k127_3946276_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1664.0
TH2_k127_3946276_20 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000005081 209.0
TH2_k127_3946276_21 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000001384 211.0
TH2_k127_3946276_22 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000002122 215.0
TH2_k127_3946276_23 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000002835 204.0
TH2_k127_3946276_24 rRNA binding K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000003132 203.0
TH2_k127_3946276_25 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000306 203.0
TH2_k127_3946276_26 kinase activity K02848,K07178,K19302 - 2.7.11.1,3.6.1.27 0.0000000000000000000000000000000000000000000000000000004911 203.0
TH2_k127_3946276_27 Membrane bound O-acyl transferase family - - - 0.000000000000000000000000000000000000000000000000000001495 207.0
TH2_k127_3946276_28 PFAM Glycosyl transferase, group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000002428 201.0
TH2_k127_3946276_29 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000004259 189.0
TH2_k127_3946276_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.182e-301 940.0
TH2_k127_3946276_30 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000002085 190.0
TH2_k127_3946276_31 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000008402 190.0
TH2_k127_3946276_32 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000009656 184.0
TH2_k127_3946276_33 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000004954 175.0
TH2_k127_3946276_34 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000147 174.0
TH2_k127_3946276_35 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.0000000000000000000000000000000000000000000003077 171.0
TH2_k127_3946276_36 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000001986 171.0
TH2_k127_3946276_37 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000168 153.0
TH2_k127_3946276_38 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000002285 156.0
TH2_k127_3946276_39 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001245 151.0
TH2_k127_3946276_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.262e-205 644.0
TH2_k127_3946276_40 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000007366 150.0
TH2_k127_3946276_41 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.00000000000000000000000000000000000002359 157.0
TH2_k127_3946276_42 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000001907 142.0
TH2_k127_3946276_43 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006751 135.0
TH2_k127_3946276_44 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000005321 125.0
TH2_k127_3946276_45 Involved in the tonB-independent uptake of proteins K01730,K03641 - 4.2.2.6 0.00000000000000000000000000009814 129.0
TH2_k127_3946276_46 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000001775 118.0
TH2_k127_3946276_47 YndJ-like protein - - - 0.00000000000000000000000438 117.0
TH2_k127_3946276_48 protein kinase activity - - - 0.00000000000000000000001333 111.0
TH2_k127_3946276_49 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001985 103.0
TH2_k127_3946276_5 PFAM Carbamoyltransferase K00612 - - 6.874e-198 626.0
TH2_k127_3946276_50 - - - - 0.00000000000000000000002479 108.0
TH2_k127_3946276_51 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000002592 100.0
TH2_k127_3946276_52 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000004158 100.0
TH2_k127_3946276_53 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000003806 91.0
TH2_k127_3946276_54 sam-dependent methyltransferase - - - 0.000000000000000006289 93.0
TH2_k127_3946276_55 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000006987 94.0
TH2_k127_3946276_56 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000002388 77.0
TH2_k127_3946276_57 - - - - 0.0000000000001053 80.0
TH2_k127_3946276_58 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000002015 70.0
TH2_k127_3946276_59 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000001137 71.0
TH2_k127_3946276_6 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 490.0
TH2_k127_3946276_60 Vitamin K-dependent gamma-carboxylase - - - 0.0000000003962 66.0
TH2_k127_3946276_61 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000002937 67.0
TH2_k127_3946276_62 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000003031 69.0
TH2_k127_3946276_63 Putative S-adenosyl-L-methionine-dependent methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.00000002344 64.0
TH2_k127_3946276_64 Putative zinc-finger - - - 0.00000008931 60.0
TH2_k127_3946276_65 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000009158 59.0
TH2_k127_3946276_66 Belongs to the SecE SEC61-gamma family K03073 - - 0.000001554 52.0
TH2_k127_3946276_67 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000002343 51.0
TH2_k127_3946276_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 457.0
TH2_k127_3946276_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 346.0
TH2_k127_3946276_9 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 319.0
TH2_k127_3946288_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000007453 233.0
TH2_k127_3955372_0 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 561.0
TH2_k127_3955372_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 420.0
TH2_k127_3955372_2 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 370.0
TH2_k127_3955372_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 367.0
TH2_k127_3955372_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000005274 132.0
TH2_k127_3955372_5 radical SAM domain protein - - - 0.000000000000000000000007303 105.0
TH2_k127_3955372_6 ACT domain K03567 - - 0.0000000000000000000005496 103.0
TH2_k127_3987294_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 3.702e-256 804.0
TH2_k127_3987294_1 PKD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 454.0
TH2_k127_3987294_10 Domain of unknown function (DUF4338) - - - 0.00000000127 63.0
TH2_k127_3987294_11 Serine aminopeptidase, S33 K06889 - - 0.000000005835 61.0
TH2_k127_3987294_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 430.0
TH2_k127_3987294_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 398.0
TH2_k127_3987294_4 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 385.0
TH2_k127_3987294_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 348.0
TH2_k127_3987294_6 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000215 158.0
TH2_k127_3987294_7 - - - - 0.0000000000000000000000000000002653 130.0
TH2_k127_3987294_8 acr, cog1399 K07040 - - 0.0000000000000000001182 94.0
TH2_k127_3987294_9 Ribosomal L32p protein family K02911 - - 0.00000000000001229 75.0
TH2_k127_4065527_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 591.0
TH2_k127_4065527_1 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005459 254.0
TH2_k127_4065527_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000006866 220.0
TH2_k127_4101425_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 582.0
TH2_k127_4101425_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 498.0
TH2_k127_4101425_10 transposase activity K07497 - - 0.0000006124 62.0
TH2_k127_4101425_11 PFAM Integrase, catalytic K07497 - - 0.0000008969 51.0
TH2_k127_4101425_12 - - - - 0.000004603 53.0
TH2_k127_4101425_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 478.0
TH2_k127_4101425_3 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 415.0
TH2_k127_4101425_4 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 394.0
TH2_k127_4101425_5 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 366.0
TH2_k127_4101425_6 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000001445 190.0
TH2_k127_4101425_7 Response regulator, receiver - - - 0.0000000000000000000000005315 109.0
TH2_k127_4101425_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000009622 89.0
TH2_k127_4101425_9 positive regulation of growth rate - - - 0.00000000000000632 83.0
TH2_k127_4214807_0 DNA topoisomerase II activity K02469 - 5.99.1.3 6.704e-311 978.0
TH2_k127_4214807_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 5.612e-234 748.0
TH2_k127_4214807_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 500.0
TH2_k127_4214807_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 463.0
TH2_k127_4214807_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000003871 178.0
TH2_k127_4214807_5 HEPN domain - - - 0.0000000007464 67.0
TH2_k127_4214807_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.000000003939 58.0
TH2_k127_4230714_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 569.0
TH2_k127_4230714_1 Preprotein translocase subunit K03210 - - 0.0000000000000000000005069 97.0
TH2_k127_4238382_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 407.0
TH2_k127_4238382_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 396.0
TH2_k127_4238382_10 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000001435 130.0
TH2_k127_4238382_11 - - - - 0.00000000000000000000000000000004313 126.0
TH2_k127_4238382_12 Bacterial membrane protein YfhO - - - 0.0000135 59.0
TH2_k127_4238382_2 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 373.0
TH2_k127_4238382_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 344.0
TH2_k127_4238382_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000001145 259.0
TH2_k127_4238382_5 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007052 250.0
TH2_k127_4238382_6 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000005892 241.0
TH2_k127_4238382_7 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000001141 230.0
TH2_k127_4238382_8 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000005194 202.0
TH2_k127_4238382_9 - - - - 0.000000000000000000000000000000007278 136.0
TH2_k127_429320_0 Pectate lyase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 381.0
TH2_k127_429320_1 Tetratricopeptide repeat - - - 0.000000000000000000000057 107.0
TH2_k127_4295464_0 4Fe-4S dicluster domain K00184 - - 0.0 1176.0
TH2_k127_4295464_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.782e-268 836.0
TH2_k127_4295464_10 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 306.0
TH2_k127_4295464_11 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 296.0
TH2_k127_4295464_12 Binding-protein-dependent transport system inner membrane component K02025,K05814,K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 270.0
TH2_k127_4295464_13 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002921 245.0
TH2_k127_4295464_14 Sugar ABC transporter permease K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000001381 254.0
TH2_k127_4295464_15 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000005394 243.0
TH2_k127_4295464_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000001861 188.0
TH2_k127_4295464_17 - - - - 0.0000000000000001377 92.0
TH2_k127_4295464_18 - - - - 0.000000000000008128 87.0
TH2_k127_4295464_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.077e-247 801.0
TH2_k127_4295464_20 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000005348 61.0
TH2_k127_4295464_3 Polysulphide reductase, NrfD K00185 - - 5.13e-217 681.0
TH2_k127_4295464_4 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 402.0
TH2_k127_4295464_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 383.0
TH2_k127_4295464_6 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 365.0
TH2_k127_4295464_7 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 355.0
TH2_k127_4295464_8 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 325.0
TH2_k127_4295464_9 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 305.0
TH2_k127_429745_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 9.17e-245 769.0
TH2_k127_429745_1 transporter - - - 0.00000000000000000000000138 114.0
TH2_k127_429745_2 membrane-bound metal-dependent K07038 - - 0.0000000000000001324 91.0
TH2_k127_4317106_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002981 228.0
TH2_k127_4317106_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000001126 220.0
TH2_k127_434815_0 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000003024 255.0
TH2_k127_434815_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000997 147.0
TH2_k127_444819_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 5e-323 997.0
TH2_k127_444819_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 7.207e-296 920.0
TH2_k127_444819_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000001003 203.0
TH2_k127_444819_11 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000002576 165.0
TH2_k127_444819_12 Sigma-70, region 4 - - - 0.000000000000000000000000000000003959 138.0
TH2_k127_444819_14 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000001934 112.0
TH2_k127_444819_15 oxidase subunit K08738 - - 0.00000000000003024 85.0
TH2_k127_444819_16 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0000000003907 72.0
TH2_k127_444819_17 - - - - 0.00000007233 58.0
TH2_k127_444819_18 Heavy metal resistance protein - - - 0.00003284 54.0
TH2_k127_444819_2 B12 binding domain - - - 3.582e-195 619.0
TH2_k127_444819_3 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 378.0
TH2_k127_444819_4 Cytochrome c K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 372.0
TH2_k127_444819_5 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 357.0
TH2_k127_444819_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 316.0
TH2_k127_444819_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002165 251.0
TH2_k127_444819_8 SCO1/SenC K07152,K08976 - - 0.000000000000000000000000000000000000000000000000000000000000001003 241.0
TH2_k127_444819_9 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000000000000002728 214.0
TH2_k127_4459967_0 Superfamily I DNA and RNA helicases and helicase subunits - - - 0.0 1750.0
TH2_k127_4459967_1 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 560.0
TH2_k127_4459967_10 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000006734 107.0
TH2_k127_4459967_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000001466 76.0
TH2_k127_4459967_12 Addiction module component, TIGR02574 family - - - 0.000000000001703 69.0
TH2_k127_4459967_13 - - - - 0.00000000002067 66.0
TH2_k127_4459967_15 Protein of unknown function (DUF2662) - - - 0.000004097 58.0
TH2_k127_4459967_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 497.0
TH2_k127_4459967_3 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 441.0
TH2_k127_4459967_4 Cytochrome d ubiquinol oxidase, subunit II K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 424.0
TH2_k127_4459967_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 404.0
TH2_k127_4459967_6 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 370.0
TH2_k127_4459967_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006552 275.0
TH2_k127_4459967_8 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000006453 239.0
TH2_k127_4459967_9 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001109 253.0
TH2_k127_4461193_0 Associated with various cellular activities - - - 0.0 1622.0
TH2_k127_4461193_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 1.549e-261 818.0
TH2_k127_4461193_10 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 445.0
TH2_k127_4461193_11 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 419.0
TH2_k127_4461193_12 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 356.0
TH2_k127_4461193_13 -binding domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 349.0
TH2_k127_4461193_14 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 305.0
TH2_k127_4461193_15 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000119 287.0
TH2_k127_4461193_16 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007666 278.0
TH2_k127_4461193_17 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000004543 284.0
TH2_k127_4461193_18 Pfam:Arch_ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001328 258.0
TH2_k127_4461193_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008776 248.0
TH2_k127_4461193_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.596e-207 658.0
TH2_k127_4461193_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000001259 236.0
TH2_k127_4461193_21 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000005778 216.0
TH2_k127_4461193_22 coenzyme F420 hydrogenase activity K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000003259 208.0
TH2_k127_4461193_23 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000001472 184.0
TH2_k127_4461193_24 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000002395 173.0
TH2_k127_4461193_25 Ferredoxin K02230 - 6.6.1.2 0.000000000000000000000000000000000000000000005162 168.0
TH2_k127_4461193_26 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000003535 163.0
TH2_k127_4461193_27 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.000000000000000000000000000000000000014 155.0
TH2_k127_4461193_28 xylan catabolic process K03932 - - 0.000000000000000000000000000000000002213 160.0
TH2_k127_4461193_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000003238 134.0
TH2_k127_4461193_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 8.463e-198 626.0
TH2_k127_4461193_30 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000001354 120.0
TH2_k127_4461193_31 Ferredoxin K00335,K17992 - 1.12.1.3,1.6.5.3 0.00000000000000000000000897 105.0
TH2_k127_4461193_32 hydrogenase maturation protease - - - 0.0000000000000000000003176 102.0
TH2_k127_4461193_33 Protein of unknown function (DUF3108) - - - 0.000000000000000000001959 106.0
TH2_k127_4461193_34 DRTGG domain - - - 0.000000000000000000005088 97.0
TH2_k127_4461193_35 Transposase DDE domain group 1 - - - 0.0000000000000000000174 93.0
TH2_k127_4461193_36 Esterase PHB depolymerase K03932 - - 0.00000000000000000003522 107.0
TH2_k127_4461193_37 Transposase zinc-binding domain - - - 0.00000000000000001207 86.0
TH2_k127_4461193_38 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000003423 85.0
TH2_k127_4461193_39 Glutathione S-transferase, N-terminal domain - - - 0.000000000000129 75.0
TH2_k127_4461193_4 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 595.0
TH2_k127_4461193_40 Sigma-70, region 4 - - - 0.00000000007249 67.0
TH2_k127_4461193_41 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000007025 69.0
TH2_k127_4461193_42 Dienelactone hydrolase family - - - 0.00000004347 67.0
TH2_k127_4461193_43 acid phosphatase activity - - - 0.00000006724 56.0
TH2_k127_4461193_44 Integral membrane protein TerC family - - - 0.00000007044 56.0
TH2_k127_4461193_45 Prokaryotic N-terminal methylation motif - - - 0.000005968 55.0
TH2_k127_4461193_46 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000393 48.0
TH2_k127_4461193_47 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0006739 50.0
TH2_k127_4461193_48 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0009972 48.0
TH2_k127_4461193_5 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 541.0
TH2_k127_4461193_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 551.0
TH2_k127_4461193_7 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 544.0
TH2_k127_4461193_8 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 507.0
TH2_k127_4461193_9 Na Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 478.0
TH2_k127_4504926_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.438e-198 625.0
TH2_k127_4504926_1 CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 329.0
TH2_k127_4512867_0 Protein of unknown function DUF116 - - - 2.054e-227 721.0
TH2_k127_4512867_1 Aminotransferase class-III K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 576.0
TH2_k127_4512867_10 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000242 214.0
TH2_k127_4512867_11 soluble inorganic K01507 GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0008150,GO:0010035,GO:0010038,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896 3.6.1.1 0.00000000000000000000000000000000000000000000000000001396 195.0
TH2_k127_4512867_12 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000008284 183.0
TH2_k127_4512867_13 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000005521 176.0
TH2_k127_4512867_14 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000008858 171.0
TH2_k127_4512867_15 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000002705 180.0
TH2_k127_4512867_16 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000002023 172.0
TH2_k127_4512867_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000004574 168.0
TH2_k127_4512867_18 Belongs to the ompA family K03640 - - 0.0000000000000000000000000002157 122.0
TH2_k127_4512867_19 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000001262 111.0
TH2_k127_4512867_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 518.0
TH2_k127_4512867_20 - - - - 0.000000000000000000000007285 111.0
TH2_k127_4512867_21 Putative porin - - - 0.000000000000000009186 94.0
TH2_k127_4512867_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000003732 66.0
TH2_k127_4512867_23 - - - - 0.0000001041 60.0
TH2_k127_4512867_24 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000001918 61.0
TH2_k127_4512867_25 TonB C terminal K03832 - - 0.0002051 53.0
TH2_k127_4512867_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 468.0
TH2_k127_4512867_4 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 405.0
TH2_k127_4512867_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 402.0
TH2_k127_4512867_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
TH2_k127_4512867_7 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001328 271.0
TH2_k127_4512867_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003425 254.0
TH2_k127_4512867_9 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000006275 247.0
TH2_k127_4521602_0 Aminotransferase class I and II K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 379.0
TH2_k127_4521602_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003263 262.0
TH2_k127_4521602_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000001463 128.0
TH2_k127_4525055_0 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 379.0
TH2_k127_4525055_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000001254 234.0
TH2_k127_4525055_2 Biotin-lipoyl like - - - 0.0000000000000000000000001279 119.0
TH2_k127_4525055_3 Protein of unknown function (DUF2892) - - - 0.00000000000000000008651 94.0
TH2_k127_4525055_4 Putative zinc-finger - - - 0.0000000000008078 72.0
TH2_k127_4525055_5 Cache domain - - - 0.000000000002945 77.0
TH2_k127_4587370_0 SNF2 family N-terminal domain - - - 4.271e-249 810.0
TH2_k127_4587370_1 amino acid - - - 0.0000000000000000000000143 104.0
TH2_k127_4622555_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1166.0
TH2_k127_4637745_0 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000001081 214.0
TH2_k127_4637745_1 Transketolase, pyrimidine binding domain - - - 0.000000000000000000000000000000000000000000933 168.0
TH2_k127_4637745_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000001145 147.0
TH2_k127_4637745_3 23S rRNA-intervening sequence protein - - - 0.000000000000002854 87.0
TH2_k127_4637745_4 tagaturonate epimerase - - - 0.000000000006984 68.0
TH2_k127_4637745_5 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000361 53.0
TH2_k127_4648848_0 Pyruvate:ferredoxin oxidoreductase core domain II - - - 9.245e-221 700.0
TH2_k127_4648848_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 417.0
TH2_k127_4648848_10 - - - - 0.000000000000000000000002355 111.0
TH2_k127_4648848_11 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000001904 65.0
TH2_k127_4648848_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 401.0
TH2_k127_4648848_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 407.0
TH2_k127_4648848_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 315.0
TH2_k127_4648848_5 myo-inosose-2 dehydratase activity K03079,K03335 - 4.2.1.44,5.1.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 314.0
TH2_k127_4648848_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000178 287.0
TH2_k127_4648848_7 - - - - 0.000000000000000000000000000000000000000000000000000000000003441 211.0
TH2_k127_4648848_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000004019 191.0
TH2_k127_4648848_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000002058 129.0
TH2_k127_4667435_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1338.0
TH2_k127_4667435_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 554.0
TH2_k127_4667435_2 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 347.0
TH2_k127_4667435_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001063 294.0
TH2_k127_4667435_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 269.0
TH2_k127_4667435_5 NmrA-like family - - - 0.000000000000000000000000000000000000000000002966 166.0
TH2_k127_4669323_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 424.0
TH2_k127_4669323_1 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000001356 222.0
TH2_k127_4669323_2 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000008934 212.0
TH2_k127_4673430_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2471.0
TH2_k127_4673430_1 Peptidase_C39 like family - - - 0.0 1078.0
TH2_k127_4673430_10 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000002437 151.0
TH2_k127_4673430_11 Sulfotransferase family - - - 0.000000000000000000000000000000000004123 158.0
TH2_k127_4673430_12 Serpin peptidase inhibitor, clade B (ovalbumin), member 1 K13963 GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0009892,GO:0009894,GO:0009987,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034774,GO:0036230,GO:0042119,GO:0042176,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043299,GO:0043312,GO:0044092,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.000000000000000003385 93.0
TH2_k127_4673430_13 Sulfotransferase domain - - - 0.0000000000001145 81.0
TH2_k127_4673430_14 zinc ion binding - - - 0.0000007673 59.0
TH2_k127_4673430_15 Preprotein translocase SecG subunit K03075 - - 0.00006981 52.0
TH2_k127_4673430_16 Sulfotransferase domain - - - 0.0004353 44.0
TH2_k127_4673430_2 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 576.0
TH2_k127_4673430_3 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 460.0
TH2_k127_4673430_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 301.0
TH2_k127_4673430_5 nitrogen compound transport K02033,K15581 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 302.0
TH2_k127_4673430_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 293.0
TH2_k127_4673430_8 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007284 280.0
TH2_k127_4673430_9 Protein conserved in bacteria K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000006658 248.0
TH2_k127_4685034_0 AcrB/AcrD/AcrF family - - - 0.0 1320.0
TH2_k127_4685034_1 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 7.429e-234 745.0
TH2_k127_4685034_10 - - - - 0.00000000000005852 84.0
TH2_k127_4685034_11 WD40-like repeat - - - 0.0000001089 65.0
TH2_k127_4685034_12 - - - - 0.000001099 55.0
TH2_k127_4685034_13 beta-propeller repeat - - - 0.0007556 53.0
TH2_k127_4685034_2 ABC transporter K06147 - - 2.443e-222 708.0
TH2_k127_4685034_3 ABC transporter K06147 - - 6.33e-201 645.0
TH2_k127_4685034_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 453.0
TH2_k127_4685034_5 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 400.0
TH2_k127_4685034_6 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 310.0
TH2_k127_4685034_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 324.0
TH2_k127_4685034_8 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000000000000000000000000000000000000000009307 218.0
TH2_k127_4685034_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000006418 162.0
TH2_k127_4700313_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 606.0
TH2_k127_4700313_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 511.0
TH2_k127_4700313_10 nitrogen compound transport K02033,K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 296.0
TH2_k127_4700313_11 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 311.0
TH2_k127_4700313_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000681 293.0
TH2_k127_4700313_13 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000001182 261.0
TH2_k127_4700313_14 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000001039 228.0
TH2_k127_4700313_15 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000001149 189.0
TH2_k127_4700313_16 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000005244 160.0
TH2_k127_4700313_17 Transcriptional regulator K07506 - - 0.0000000000000000000000000001154 126.0
TH2_k127_4700313_18 chorismate lyase activity - - - 0.00000000000000000001695 100.0
TH2_k127_4700313_19 ABC transporter (Permease) K02004 - - 0.00000000000003799 86.0
TH2_k127_4700313_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 452.0
TH2_k127_4700313_3 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 402.0
TH2_k127_4700313_4 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 398.0
TH2_k127_4700313_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 362.0
TH2_k127_4700313_6 PFAM Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 348.0
TH2_k127_4700313_7 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 333.0
TH2_k127_4700313_8 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 312.0
TH2_k127_4700313_9 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 305.0
TH2_k127_4703961_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 527.0
TH2_k127_4703961_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 417.0
TH2_k127_4703961_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009539 278.0
TH2_k127_4703961_3 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002411 281.0
TH2_k127_4703961_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002354 263.0
TH2_k127_4703961_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000007745 126.0
TH2_k127_4703961_6 ribosomal protein L31 K02909 - - 0.0000000000000000000000006179 104.0
TH2_k127_4703961_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000004018 91.0
TH2_k127_4703961_8 Sodium:solute symporter family K14393 - - 0.00000000000000001965 85.0
TH2_k127_4703961_9 Sodium:solute symporter family K14393 - - 0.000001533 60.0
TH2_k127_4737197_0 Mur ligase middle domain protein K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 465.0
TH2_k127_4737197_1 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 299.0
TH2_k127_4737197_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000002043 243.0
TH2_k127_4737197_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000002361 241.0
TH2_k127_4737197_4 8-oxoguanine DNA glycosylase, N-terminal domain K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000006766 235.0
TH2_k127_4737197_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000001267 162.0
TH2_k127_4737197_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000001352 134.0
TH2_k127_4737197_7 type II secretion system protein K02455 - - 0.00000000000000002559 94.0
TH2_k127_4810582_0 PFAM Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 572.0
TH2_k127_4810582_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 445.0
TH2_k127_4810582_2 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002612 264.0
TH2_k127_4810582_3 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000007471 168.0
TH2_k127_4810582_4 YMGG-like Gly-zipper - - - 0.000000000000000000002517 100.0
TH2_k127_4887759_0 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 607.0
TH2_k127_4887759_1 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 429.0
TH2_k127_4887759_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 358.0
TH2_k127_4887759_3 Type I site-specific restriction-modification system, R (Restriction) subunit and related K01156 - 3.1.21.5 0.00000000000000000000000000000000000000000000000000000005858 201.0
TH2_k127_4887759_4 PFAM Acetyl xylan esterase K01060 - 3.1.1.41 0.0000000000000000000000000003083 118.0
TH2_k127_4887759_5 DNA primase - - - 0.0000000000000000000000000005629 132.0
TH2_k127_4889967_0 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 421.0
TH2_k127_4889967_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 387.0
TH2_k127_4889967_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 349.0
TH2_k127_4889967_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000003067 264.0
TH2_k127_4889967_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002624 258.0
TH2_k127_4889967_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002779 258.0
TH2_k127_4889967_6 Glycosyl transferase, family 2 - - - 0.000000000000000008997 87.0
TH2_k127_4926292_0 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 347.0
TH2_k127_4926292_1 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001354 266.0
TH2_k127_4926292_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000001378 93.0
TH2_k127_4926292_3 Periplasmic binding protein domain K10439 - - 0.000000007226 61.0
TH2_k127_4950907_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 9.176e-253 805.0
TH2_k127_4950907_1 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 400.0
TH2_k127_4950907_10 - - - - 0.0009062 51.0
TH2_k127_4950907_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 357.0
TH2_k127_4950907_3 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 305.0
TH2_k127_4950907_4 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000003354 138.0
TH2_k127_4950907_5 AsmA-like C-terminal region - - - 0.00000000000000000000000232 121.0
TH2_k127_4950907_6 Transposase DDE domain group 1 - - - 0.00000000000003526 79.0
TH2_k127_4950907_7 Protein of unknown function (DUF2905) - - - 0.00000000000005601 79.0
TH2_k127_4950907_8 - - - - 0.0000000006073 68.0
TH2_k127_4950907_9 MFS/sugar transport protein K16211 - - 0.0000002724 64.0
TH2_k127_5001593_0 beta-galactosidase activity K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 378.0
TH2_k127_5001593_1 PFAM AhpC TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002372 232.0
TH2_k127_5043660_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 8.162e-217 693.0
TH2_k127_5043660_1 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 555.0
TH2_k127_5043660_2 Glycosyl hydrolase family 65, N-terminal domain K04844,K21355 - 2.4.1.332 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 550.0
TH2_k127_5043660_3 Aminotransferase class-III K09251 - 2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 530.0
TH2_k127_5043660_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 360.0
TH2_k127_5043660_5 SMP-30 Gluconolaconase LRE domain protein K14274 GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 319.0
TH2_k127_5043660_6 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000000000000000000000004135 201.0
TH2_k127_5043660_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000001316 184.0
TH2_k127_5043660_8 Protein of unknown function (DUF1573) - - - 0.0003928 52.0
TH2_k127_5059316_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.433e-251 788.0
TH2_k127_5059316_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 481.0
TH2_k127_5059316_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 415.0
TH2_k127_5059316_3 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000008859 262.0
TH2_k127_5059316_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002172 263.0
TH2_k127_5059316_5 regulation of translation K03530,K04764 - - 0.0000000000000000000000000001691 123.0
TH2_k127_5059316_6 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000006376 115.0
TH2_k127_5059316_7 - - - - 0.000000000003499 75.0
TH2_k127_5063309_0 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 447.0
TH2_k127_5063309_1 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 300.0
TH2_k127_5063309_2 Nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000225 263.0
TH2_k127_5063309_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000299 231.0
TH2_k127_5063309_4 Histidine kinase - - - 0.000000000000000000000000000001104 127.0
TH2_k127_5063309_5 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000008827 111.0
TH2_k127_508902_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 7.615e-241 765.0
TH2_k127_508902_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.148e-201 653.0
TH2_k127_508902_10 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000009561 165.0
TH2_k127_508902_11 Bacterial PH domain - - - 0.0000000000000000000000000000000004169 136.0
TH2_k127_508902_12 - - - - 0.00000000000000000000000001023 116.0
TH2_k127_508902_13 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000001374 121.0
TH2_k127_508902_14 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000004935 98.0
TH2_k127_508902_15 Protein of unknown function (DUF2934) - - - 0.000003198 55.0
TH2_k127_508902_16 Tetratricopeptide repeat - - - 0.00001235 59.0
TH2_k127_508902_17 MORN repeat variant - - - 0.0002366 51.0
TH2_k127_508902_2 AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 557.0
TH2_k127_508902_3 Alpha mannosidase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 559.0
TH2_k127_508902_4 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 505.0
TH2_k127_508902_5 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 393.0
TH2_k127_508902_6 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
TH2_k127_508902_7 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 288.0
TH2_k127_508902_8 GTP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003748 290.0
TH2_k127_508902_9 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000306 234.0
TH2_k127_5118349_0 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000001021 185.0
TH2_k127_5118349_1 Beta-L-arabinofuranosidase, GH127 K02169 - 2.1.1.197 0.0000000000000000000001508 104.0
TH2_k127_5118349_2 conserved protein (DUF2088) - - - 0.0000000000000000000004913 100.0
TH2_k127_5118349_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0005221 45.0
TH2_k127_52108_0 PFAM magnesium chelatase ChlI subunit K07391 - - 4.705e-205 650.0
TH2_k127_52108_1 SUPERFAMILY SSF53098, Polynucleotidyl transferase, Ribonuclease H fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000592 258.0
TH2_k127_52108_2 Phospholipase/Carboxylesterase - - - 0.0000000000006968 81.0
TH2_k127_5210961_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 308.0
TH2_k127_5210961_1 R3H domain - - - 0.000000000000000000004004 101.0
TH2_k127_5210961_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000001846 100.0
TH2_k127_5210961_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000002907 71.0
TH2_k127_5210961_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000001332 55.0
TH2_k127_5222081_0 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 529.0
TH2_k127_5222081_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002495 256.0
TH2_k127_5222081_2 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000000005627 199.0
TH2_k127_5222081_4 HNH endonuclease - - - 0.0000000000000000003791 93.0
TH2_k127_5222081_5 - - - - 0.000000001106 62.0
TH2_k127_5222081_6 - - - - 0.00000001568 56.0
TH2_k127_5284486_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 435.0
TH2_k127_5284486_1 PDZ domain (Also known as DHR K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 333.0
TH2_k127_5284486_2 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000008797 209.0
TH2_k127_5284486_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000005684 151.0
TH2_k127_5284486_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000001749 106.0
TH2_k127_5284486_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000002529 76.0
TH2_k127_5423897_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000001259 188.0
TH2_k127_5423897_1 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.0000000000000000000000000000000000000001021 162.0
TH2_k127_5423897_2 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000007367 141.0
TH2_k127_5423897_3 Protein of unknown function (DUF1559) K02456 - - 0.0000000000000008131 87.0
TH2_k127_5423897_4 Calcineurin-like phosphoesterase K01081 - 3.1.3.5 0.00000008851 56.0
TH2_k127_5427425_0 Oligonucleotide/oligosaccharide-binding (OB)-fold K03578 - 3.6.4.13 1.821e-292 944.0
TH2_k127_5427425_1 PFAM glycoside hydrolase, family 4 K07406 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 613.0
TH2_k127_5427425_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000005471 191.0
TH2_k127_5427425_11 belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K02945,K03527,K03977,K11753,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 0.000000000000000000000000000000000000000000000006292 181.0
TH2_k127_5427425_12 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000136 169.0
TH2_k127_5427425_13 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000002264 176.0
TH2_k127_5427425_14 negative regulation of DNA-templated transcription, initiation K02616 - - 0.0000000000000000000000000000000000001182 154.0
TH2_k127_5427425_15 arsenate reductase K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000000001761 142.0
TH2_k127_5427425_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000001636 145.0
TH2_k127_5427425_17 - - - - 0.000000000000000000000007735 104.0
TH2_k127_5427425_18 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000000000000000000897 105.0
TH2_k127_5427425_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 569.0
TH2_k127_5427425_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 514.0
TH2_k127_5427425_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 495.0
TH2_k127_5427425_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 314.0
TH2_k127_5427425_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000097 286.0
TH2_k127_5427425_7 nicotinamide mononucleotide transporter K03811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008636 269.0
TH2_k127_5427425_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000003327 216.0
TH2_k127_5427425_9 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000005688 212.0
TH2_k127_5453928_0 radical SAM domain protein - - - 2.376e-211 669.0
TH2_k127_5453928_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 625.0
TH2_k127_5453928_10 PAP2 superfamily - - - 0.0000000000000000000000000002851 123.0
TH2_k127_5453928_11 - - - - 0.000000000000000000000002216 116.0
TH2_k127_5453928_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 395.0
TH2_k127_5453928_3 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 316.0
TH2_k127_5453928_4 GH3 auxin-responsive promoter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000123 283.0
TH2_k127_5453928_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000002645 216.0
TH2_k127_5453928_7 - - - - 0.000000000000000000000000000000000000000000000000000000000001312 217.0
TH2_k127_5453928_8 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit - - - 0.000000000000000000000000000000000000000000000003484 186.0
TH2_k127_5453928_9 SnoaL-like domain K01822 - 5.3.3.1 0.00000000000000000000000000000000000003304 156.0
TH2_k127_5467045_0 4Fe-4S binding domain - - - 1.007e-280 882.0
TH2_k127_5467045_1 COG0553 Superfamily II DNA RNA helicases, SNF2 family K03580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 419.0
TH2_k127_5467045_2 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000002683 193.0
TH2_k127_5467045_3 - - - - 0.00000000000000000000000000000000004891 138.0
TH2_k127_5467045_4 Glycogen debranching enzyme N terminal - - - 0.0003437 49.0
TH2_k127_54783_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 350.0
TH2_k127_54783_1 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000357 199.0
TH2_k127_54783_2 - - - - 0.00000000000000000000000000000000000000000000001538 174.0
TH2_k127_54783_3 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00917 - 2.7.1.144 0.0000000000000000000000000008319 124.0
TH2_k127_54783_4 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000001728 108.0
TH2_k127_54783_5 nerve growth factor signaling pathway K21440,K21486 GO:0003674,GO:0003712,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0006357,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000006127 105.0
TH2_k127_54783_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000114 85.0
TH2_k127_54783_7 Tetratricopeptide repeat - - - 0.0000000009872 71.0
TH2_k127_54783_8 Bacterial type II and III secretion system protein K02453 - - 0.000007988 57.0
TH2_k127_54783_9 PFAM Prokaryotic metallothionein K21904 - - 0.0001601 48.0
TH2_k127_5490783_0 Predicted membrane protein (DUF2339) - - - 2.052e-216 701.0
TH2_k127_5496679_0 Belongs to the glycosyl hydrolase 28 family - - - 0.000000000000000000000000000000000000000007377 171.0
TH2_k127_5496679_1 Psort location CytoplasmicMembrane, score 9.99 K19294 - - 0.00000000000000000002054 96.0
TH2_k127_5496679_2 RNA polymerase sigma factor, sigma-70 family - - - 0.0000000000000000782 89.0
TH2_k127_5496679_3 PQQ-like domain - - - 0.0000001995 58.0
TH2_k127_5511222_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 381.0
TH2_k127_5511222_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000153 276.0
TH2_k127_5511222_2 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005193 256.0
TH2_k127_5511222_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001954 257.0
TH2_k127_5511222_4 thioesterase - - - 0.000000000000000000000000000000000000000002719 159.0
TH2_k127_5546934_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 8.232e-242 771.0
TH2_k127_5546934_1 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 507.0
TH2_k127_5546934_10 - K07403 - - 0.0000000000004482 76.0
TH2_k127_5546934_11 Aerotolerance regulator N-terminal - - - 0.000000000008436 78.0
TH2_k127_5546934_12 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000006772 52.0
TH2_k127_5546934_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 464.0
TH2_k127_5546934_3 DHHA1 domain K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 451.0
TH2_k127_5546934_4 UPF0365 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 420.0
TH2_k127_5546934_5 DNA methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 306.0
TH2_k127_5546934_6 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004095 295.0
TH2_k127_5546934_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000001064 174.0
TH2_k127_5546934_8 Winged helix DNA-binding domain - - - 0.000000000000002268 81.0
TH2_k127_5546934_9 FtsX-like permease family K02004 - - 0.00000000000001322 82.0
TH2_k127_5548643_0 dioxygenase activity K18056 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046483,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.11.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 325.0
TH2_k127_5548643_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000001076 233.0
TH2_k127_5548643_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000005462 92.0
TH2_k127_556243_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 440.0
TH2_k127_556243_1 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 355.0
TH2_k127_556243_2 in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 325.0
TH2_k127_556243_3 Haloacid dehalogenase-like hydrolase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
TH2_k127_556243_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000002631 248.0
TH2_k127_556243_5 High confidence in function and specificity - - - 0.0000000000000000000000002056 120.0
TH2_k127_5578280_0 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000001457 161.0
TH2_k127_5592551_0 Molybdopterin oxidoreductase Fe4S4 domain K00370 - 1.7.5.1 0.0 1632.0
TH2_k127_5592551_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.113e-273 849.0
TH2_k127_5592551_10 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000003107 81.0
TH2_k127_5592551_11 PFAM Rieske 2Fe-2S K16937 - 1.8.5.2 0.0000001309 64.0
TH2_k127_5592551_2 TIGRFAM nitrate reductase, beta subunit K00371 - 1.7.5.1 4.383e-205 654.0
TH2_k127_5592551_3 Transporter K02575 - - 6.479e-199 628.0
TH2_k127_5592551_4 Major Facilitator Superfamily K02575 - - 3.54e-196 619.0
TH2_k127_5592551_5 Phosphoenolpyruvate carboxylase K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 566.0
TH2_k127_5592551_6 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 429.0
TH2_k127_5592551_7 PFAM Cytochrome b b6 K02635 - - 0.000000000000000000000000000000000000000000000000000000000000000002523 243.0
TH2_k127_5592551_8 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.00000000000000000000000000000000000000000000002999 186.0
TH2_k127_5592551_9 PFAM Cytochrome C - - - 0.000000000000004128 85.0
TH2_k127_5596561_0 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 2.087e-208 656.0
TH2_k127_5596561_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 470.0
TH2_k127_5596561_10 beta-propeller repeat - - - 0.0000000000000000001078 91.0
TH2_k127_5596561_11 PQQ-like domain - - - 0.000000000006141 78.0
TH2_k127_5596561_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 436.0
TH2_k127_5596561_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 416.0
TH2_k127_5596561_4 DUF218 domain K03748 - - 0.00000000000000000000000000000000000000000000000000000002089 204.0
TH2_k127_5596561_5 - - - - 0.00000000000000000000000000000000000000000000000004243 184.0
TH2_k127_5596561_6 HTH-like domain K07497 - - 0.00000000000000000000000000000000000000000006421 171.0
TH2_k127_5596561_7 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000003586 160.0
TH2_k127_5596561_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000002378 156.0
TH2_k127_5596561_9 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000646 104.0
TH2_k127_5622774_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000567 272.0
TH2_k127_5622774_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000001092 205.0
TH2_k127_5622774_2 Domain of unknown function (DUF2088) - - - 0.0000000000000001096 89.0
TH2_k127_5648928_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1155.0
TH2_k127_5648928_1 L-rhamnose isomerase (RhaA) K01813 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 595.0
TH2_k127_5648928_10 Cold-Shock Protein - - - 0.000000000000000000000004265 102.0
TH2_k127_5648928_11 Regulatory protein, FmdB family - - - 0.00000000002167 68.0
TH2_k127_5648928_12 Large extracellular alpha-helical protein K06894 - - 0.0000000004954 60.0
TH2_k127_5648928_13 Outer membrane lipoprotein-sorting protein - - - 0.000000001082 70.0
TH2_k127_5648928_14 ribosomal protein - - - 0.0007338 47.0
TH2_k127_5648928_2 DEAD DEAH box helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 541.0
TH2_k127_5648928_3 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 375.0
TH2_k127_5648928_4 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004838 275.0
TH2_k127_5648928_5 CorA-like Mg2+ transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000001792 211.0
TH2_k127_5648928_6 - - - - 0.0000000000000000000000000000000000000000000000000005284 190.0
TH2_k127_5648928_7 outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000005117 173.0
TH2_k127_5648928_8 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000003898 154.0
TH2_k127_5648928_9 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000009926 126.0
TH2_k127_5650392_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K01507,K15987 - 3.6.1.1 6.17e-290 909.0
TH2_k127_5650392_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.638e-237 752.0
TH2_k127_5650392_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 376.0
TH2_k127_5650392_3 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000399 219.0
TH2_k127_5650392_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000131 192.0
TH2_k127_5650392_5 Transcriptional regulator K02099,K02508,K07506,K18954 - - 0.00000000000000000000000000000000000000002342 165.0
TH2_k127_5650392_6 - - - - 0.000000000000000000000000000003011 134.0
TH2_k127_5650392_7 Transposase K07481 - - 0.000000000000000000000007381 117.0
TH2_k127_5650392_8 - - - - 0.000000000002561 70.0
TH2_k127_5654594_0 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 527.0
TH2_k127_5654594_1 Glycoside hydrolase, family 20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 479.0
TH2_k127_5654594_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000004247 177.0
TH2_k127_5654594_11 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000009681 182.0
TH2_k127_5654594_12 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000488 164.0
TH2_k127_5654594_13 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.0000000000000000000000000000000000000000006624 159.0
TH2_k127_5654594_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000005816 159.0
TH2_k127_5654594_15 Permease, YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000008656 150.0
TH2_k127_5654594_16 DNA-binding protein PTS system, IIA component K02806 - - 0.00000000000000000000001446 110.0
TH2_k127_5654594_17 - - - - 0.000000000000003404 80.0
TH2_k127_5654594_19 Trypsin-like peptidase domain K08372 - - 0.000001386 58.0
TH2_k127_5654594_2 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 460.0
TH2_k127_5654594_3 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 404.0
TH2_k127_5654594_4 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002811 292.0
TH2_k127_5654594_5 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001504 280.0
TH2_k127_5654594_6 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
TH2_k127_5654594_7 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000002263 227.0
TH2_k127_5654594_8 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000001903 231.0
TH2_k127_5654594_9 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000009606 200.0
TH2_k127_5655427_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 581.0
TH2_k127_5655427_1 Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 576.0
TH2_k127_5655427_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 336.0
TH2_k127_5655427_3 ERCC4 domain - - - 0.000000000000000000000000000000000000000000000000000000007679 205.0
TH2_k127_5655427_5 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000007613 191.0
TH2_k127_5655427_6 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000007329 147.0
TH2_k127_5655427_7 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000001802 141.0
TH2_k127_5655427_8 - - - - 0.0000000000001463 83.0
TH2_k127_5655427_9 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000005577 54.0
TH2_k127_5655436_0 Alpha amylase catalytic region K01182,K01187,K01226,K05343 - 3.2.1.1,3.2.1.10,3.2.1.20,3.2.1.93,5.4.99.16 3.004e-252 790.0
TH2_k127_5655436_1 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 579.0
TH2_k127_5655436_10 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 0.0003617 44.0
TH2_k127_5655436_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 417.0
TH2_k127_5655436_3 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 377.0
TH2_k127_5655436_4 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 380.0
TH2_k127_5655436_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 309.0
TH2_k127_5655436_6 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000001883 195.0
TH2_k127_5655436_7 RHS Repeat - - - 0.000000000000000000000000001258 125.0
TH2_k127_5655436_8 DNA uptake protein and related DNA-binding K02237 - - 0.000000000002404 78.0
TH2_k127_5655436_9 domain, Protein K21449 - - 0.00000177 62.0
TH2_k127_5665481_0 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 3.723e-239 755.0
TH2_k127_5665481_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 476.0
TH2_k127_5665481_10 Aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000266 224.0
TH2_k127_5665481_11 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000756 169.0
TH2_k127_5665481_12 - - - - 0.000000000000000000000000000000009569 135.0
TH2_k127_5665481_13 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000000000000000000000123 125.0
TH2_k127_5665481_14 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000001093 91.0
TH2_k127_5665481_15 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.00000000001275 79.0
TH2_k127_5665481_16 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000003485 62.0
TH2_k127_5665481_2 COG1108 ABC-type Mn2 Zn2 transport systems permease K11708 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 433.0
TH2_k127_5665481_3 Iron dependent repressor, metal binding and dimerisation domain K09819,K11709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 423.0
TH2_k127_5665481_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 422.0
TH2_k127_5665481_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 395.0
TH2_k127_5665481_6 ABC transporter K09820,K11710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 372.0
TH2_k127_5665481_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 316.0
TH2_k127_5665481_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 314.0
TH2_k127_5665481_9 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 288.0
TH2_k127_5668968_0 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 542.0
TH2_k127_5668968_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 388.0
TH2_k127_5668968_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 330.0
TH2_k127_5668968_3 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008897 254.0
TH2_k127_5668968_4 HRDC domain K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.000000000000004477 78.0
TH2_k127_5687422_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 616.0
TH2_k127_5687422_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 561.0
TH2_k127_5687422_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 439.0
TH2_k127_5687422_3 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 409.0
TH2_k127_5687422_4 PFAM Integrase catalytic - - - 0.0000000000000000004678 100.0
TH2_k127_5687422_5 response regulator receiver K07315 - 3.1.3.3 0.000000000000005032 83.0
TH2_k127_5696851_0 Aldehyde dehydrogenase family - - - 1.693e-222 701.0
TH2_k127_5696851_1 PQQ-like domain - - - 6.341e-215 692.0
TH2_k127_5696851_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000001314 181.0
TH2_k127_5696851_11 DNA-binding transcription factor activity K06075,K22296 - - 0.0000000000000000000000000000000000000000001829 164.0
TH2_k127_5696851_12 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000005464 141.0
TH2_k127_5696851_13 Neutral alkaline nonlysosomal ceramidase - - - 0.0000000000001737 82.0
TH2_k127_5696851_14 Protein of unknown function (DUF1573) - - - 0.000000000711 71.0
TH2_k127_5696851_15 Protein of unknown function (DUF3311) - - - 0.00000002794 61.0
TH2_k127_5696851_16 Transposase IS200 like - - - 0.0005809 42.0
TH2_k127_5696851_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 1.176e-198 629.0
TH2_k127_5696851_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 613.0
TH2_k127_5696851_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 608.0
TH2_k127_5696851_5 Elongation factor Tu domain 2 K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 607.0
TH2_k127_5696851_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 513.0
TH2_k127_5696851_7 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 344.0
TH2_k127_5696851_8 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002188 269.0
TH2_k127_5696851_9 Acyl-CoA reductase (LuxC) - - - 0.0000000000000000000000000000000000000000000000000002775 201.0
TH2_k127_5717187_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.011e-224 719.0
TH2_k127_5717187_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 496.0
TH2_k127_5717187_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 297.0
TH2_k127_5717187_11 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 261.0
TH2_k127_5717187_12 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003486 253.0
TH2_k127_5717187_13 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000002428 251.0
TH2_k127_5717187_14 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000003433 233.0
TH2_k127_5717187_15 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000000000000000002872 216.0
TH2_k127_5717187_16 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000008357 211.0
TH2_k127_5717187_17 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000002161 207.0
TH2_k127_5717187_18 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000001602 203.0
TH2_k127_5717187_19 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000004976 171.0
TH2_k127_5717187_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 497.0
TH2_k127_5717187_20 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000001436 160.0
TH2_k127_5717187_21 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000002808 129.0
TH2_k127_5717187_22 Transcriptional regulator K02854 - - 0.0000000000000000000000005187 116.0
TH2_k127_5717187_23 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000001621 109.0
TH2_k127_5717187_24 tail specific protease K03797 - 3.4.21.102 0.00000000000005563 84.0
TH2_k127_5717187_25 - - - - 0.0000000000001145 81.0
TH2_k127_5717187_26 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.0000000000001938 73.0
TH2_k127_5717187_27 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000001125 77.0
TH2_k127_5717187_28 Xylose isomerase-like TIM barrel - - - 0.0000000002056 72.0
TH2_k127_5717187_29 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03169 - 5.99.1.2 0.0000001712 53.0
TH2_k127_5717187_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 439.0
TH2_k127_5717187_30 PFAM FecR protein - - - 0.000009774 58.0
TH2_k127_5717187_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 432.0
TH2_k127_5717187_5 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 415.0
TH2_k127_5717187_6 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 369.0
TH2_k127_5717187_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 362.0
TH2_k127_5717187_8 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 362.0
TH2_k127_5717187_9 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 305.0
TH2_k127_5731935_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.367e-260 826.0
TH2_k127_5731935_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 4.985e-216 681.0
TH2_k127_5731935_10 ATP synthase subunit C K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000204 67.0
TH2_k127_5731935_11 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000008137 60.0
TH2_k127_5731935_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 496.0
TH2_k127_5731935_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000259 241.0
TH2_k127_5731935_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000005424 238.0
TH2_k127_5731935_5 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000001802 194.0
TH2_k127_5731935_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000001598 127.0
TH2_k127_5731935_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000003277 108.0
TH2_k127_5731935_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000001719 107.0
TH2_k127_5731935_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000007942 88.0
TH2_k127_5741504_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 370.0
TH2_k127_5741504_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 376.0
TH2_k127_5741504_10 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000001297 91.0
TH2_k127_5741504_11 Probable zinc-ribbon domain - - - 0.000000000000000805 80.0
TH2_k127_5741504_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 361.0
TH2_k127_5741504_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000968 287.0
TH2_k127_5741504_4 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000044 231.0
TH2_k127_5741504_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000001627 214.0
TH2_k127_5741504_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000000001173 188.0
TH2_k127_5741504_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000002007 169.0
TH2_k127_5741504_8 phosphoribosyl-AMP cyclohydrolase activity K01496,K01497,K01814,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 0.00000000000000000000000000000000000000009053 155.0
TH2_k127_5741504_9 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.00000000000000000000004062 107.0
TH2_k127_5778693_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 1.278e-243 762.0
TH2_k127_5778693_1 lyase activity K01387,K03301 - 3.4.24.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003267 292.0
TH2_k127_5778693_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000003387 156.0
TH2_k127_5778693_3 phosphatidylglycerophosphatase activity K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000000000000004053 110.0
TH2_k127_5778760_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 425.0
TH2_k127_5778760_1 RNA pseudouridylate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 304.0
TH2_k127_5778760_2 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000002855 236.0
TH2_k127_5778760_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000009402 206.0
TH2_k127_5778760_4 domain protein K21687 - - 0.0000002296 59.0
TH2_k127_5810991_0 ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 563.0
TH2_k127_5810991_1 4 iron, 4 sulfur cluster binding K00184,K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 445.0
TH2_k127_5810991_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 346.0
TH2_k127_5810991_3 Transcriptional regulator - - - 0.0000000000000000000000000000000001528 144.0
TH2_k127_5810991_4 Putative porin - - - 0.00000000000000000000000000000457 135.0
TH2_k127_5810991_5 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000001986 68.0
TH2_k127_5812213_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 591.0
TH2_k127_5812213_1 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 429.0
TH2_k127_5812213_2 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001093 258.0
TH2_k127_5812213_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001834 216.0
TH2_k127_5812213_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000009814 170.0
TH2_k127_5825963_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008349 589.0
TH2_k127_5825963_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 513.0
TH2_k127_5825963_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 317.0
TH2_k127_5825963_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 292.0
TH2_k127_5825963_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000003614 217.0
TH2_k127_5825963_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000002833 188.0
TH2_k127_5825963_6 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000005427 186.0
TH2_k127_5832981_0 Glucuronate isomerase - - - 6.004e-224 702.0
TH2_k127_5832981_1 GDP-mannose 4,6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 484.0
TH2_k127_5832981_10 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000001124 164.0
TH2_k127_5832981_11 LigT like Phosphoesterase K01975 - 3.1.4.58 0.0000000000000000000000000000000000009373 146.0
TH2_k127_5832981_12 PFAM Class I peptide chain release factor - - - 0.0000000000000000000000000000000007627 136.0
TH2_k127_5832981_13 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000002093 133.0
TH2_k127_5832981_14 - - - - 0.000000000000000000000000004822 126.0
TH2_k127_5832981_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus - - - 0.0000000000000000000000002731 111.0
TH2_k127_5832981_16 Xylose isomerase-like TIM barrel K15652 - 4.2.1.118 0.00000000000000000001559 107.0
TH2_k127_5832981_17 alcohol dehydrogenase - - - 0.0000000000000000005951 100.0
TH2_k127_5832981_18 Putative metal-binding motif - - - 0.0000000000000003321 91.0
TH2_k127_5832981_19 AAA domain - - - 0.00000000001654 64.0
TH2_k127_5832981_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 443.0
TH2_k127_5832981_3 Anthranilate synthase component I, N terminal region K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 386.0
TH2_k127_5832981_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 300.0
TH2_k127_5832981_5 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002606 287.0
TH2_k127_5832981_6 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004698 278.0
TH2_k127_5832981_7 PFAM Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000000000000000002412 234.0
TH2_k127_5832981_8 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000005483 200.0
TH2_k127_5832981_9 PIN domain - - - 0.000000000000000000000000000000000000000001803 160.0
TH2_k127_5836970_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 402.0
TH2_k127_5836970_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000005471 252.0
TH2_k127_5836970_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000004078 218.0
TH2_k127_5836970_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000508 163.0
TH2_k127_5836970_4 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD - - - 0.00000000000000000000000000000000000000007328 158.0
TH2_k127_5836970_5 Peptidase family M50 - - - 0.0000000000000000000000000000006181 133.0
TH2_k127_5836970_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000003408 72.0
TH2_k127_5836970_7 Psort location CytoplasmicMembrane, score - - - 0.00000003041 64.0
TH2_k127_5839207_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 4.782e-222 698.0
TH2_k127_5839207_1 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 365.0
TH2_k127_5839207_2 e3 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 351.0
TH2_k127_5839207_3 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000889 67.0
TH2_k127_5870793_0 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 523.0
TH2_k127_5870793_1 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 431.0
TH2_k127_5870793_2 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002244 290.0
TH2_k127_5870793_3 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000001685 220.0
TH2_k127_5870793_4 Copper resistance protein D - - - 0.000000000000000000000000000000000000000000000000001864 185.0
TH2_k127_5870793_5 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000004565 192.0
TH2_k127_5870793_6 - - - - 0.0000000000003344 72.0
TH2_k127_5878840_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.62e-255 807.0
TH2_k127_5878840_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 499.0
TH2_k127_5878840_2 PFAM ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 358.0
TH2_k127_5878840_3 PFAM helix-turn-helix- domain containing protein AraC type K02855 - - 0.00000000000000000000000000000000000000000002385 167.0
TH2_k127_5878840_4 helicase superfamily c-terminal domain - - - 0.0000000000000000005066 91.0
TH2_k127_5913306_0 ArgE DapE Acy1 family protein K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 477.0
TH2_k127_5913306_1 self proteolysis - - - 0.000000000000000000000000000000000000000000000000002844 200.0
TH2_k127_5913306_2 peroxiredoxin activity - - - 0.000000000000000000000000000000001357 130.0
TH2_k127_5913306_3 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000001183 111.0
TH2_k127_5913306_4 self proteolysis - - - 0.00000000003235 68.0
TH2_k127_5984360_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 573.0
TH2_k127_5984360_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 498.0
TH2_k127_5984360_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 394.0
TH2_k127_5984360_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 297.0
TH2_k127_5984360_4 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000002305 163.0
TH2_k127_5984360_5 - - - - 0.0000000000000000000000000000003984 128.0
TH2_k127_5984360_6 Protein of unknown function (DUF433) - - - 0.000000000000000000001185 100.0
TH2_k127_5984360_7 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000001304 76.0
TH2_k127_5993681_0 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 444.0
TH2_k127_5993681_1 sigma-54 factor interaction domain-containing protein K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 444.0
TH2_k127_5993681_10 Putative DNA-binding protein N-terminus K01926 - - 0.00000000000000001749 86.0
TH2_k127_5993681_11 Domain of unknown function (DUF4388) - - - 0.000000001309 72.0
TH2_k127_5993681_12 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000001736 61.0
TH2_k127_5993681_13 - - - - 0.00002259 49.0
TH2_k127_5993681_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 417.0
TH2_k127_5993681_3 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000002861 203.0
TH2_k127_5993681_4 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000001524 212.0
TH2_k127_5993681_5 - - - - 0.00000000000000000000000000000000000000000000000004154 191.0
TH2_k127_5993681_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000007998 155.0
TH2_k127_5993681_7 Chromate transporter K07240 - - 0.0000000000000000000000000000005968 123.0
TH2_k127_5993681_8 Chromate transporter - - - 0.000000000000000000004181 98.0
TH2_k127_5993681_9 Putative oxidoreductase C terminal - - - 0.000000000000000001465 97.0
TH2_k127_6022996_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.886e-233 743.0
TH2_k127_6022996_1 Male sterility protein K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 442.0
TH2_k127_6022996_10 Bacterial membrane protein, YfhO - - - 0.00009372 53.0
TH2_k127_6022996_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 423.0
TH2_k127_6022996_3 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 316.0
TH2_k127_6022996_4 Calcineurin-like phosphoesterase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 303.0
TH2_k127_6022996_5 archaeal or bacterial-type flagellum-dependent cell motility K02556 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001891 290.0
TH2_k127_6022996_6 FlhB HrpN YscU SpaS Family K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005508 259.0
TH2_k127_6022996_7 Sigma-70 region 3 K02405 - - 0.0000000000000000000000000000000000000000000000000000000000003212 221.0
TH2_k127_6022996_8 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000003043 181.0
TH2_k127_6022996_9 protein localization to endoplasmic reticulum K02404 - - 0.0000000000000003025 91.0
TH2_k127_6024566_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 6.349e-303 961.0
TH2_k127_6024566_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 593.0
TH2_k127_6024566_10 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 0.00000000003237 64.0
TH2_k127_6024566_11 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system K02526 - - 0.00000002866 59.0
TH2_k127_6024566_12 Domain of unknown function (DUF2088) - - - 0.000000188 61.0
TH2_k127_6024566_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 555.0
TH2_k127_6024566_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 349.0
TH2_k127_6024566_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000005814 271.0
TH2_k127_6024566_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18306 - - 0.00000000000000000000000000000000000000000000000000000000000000000006293 246.0
TH2_k127_6024566_6 Male sterility protein K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000002076 220.0
TH2_k127_6024566_7 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000000005301 224.0
TH2_k127_6024566_8 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000001714 126.0
TH2_k127_6024566_9 - - - - 0.0000000000000000003137 102.0
TH2_k127_604853_0 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 391.0
TH2_k127_604853_1 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 313.0
TH2_k127_604853_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000009558 73.0
TH2_k127_604853_11 biopolymer transport protein K03559 - - 0.00001086 54.0
TH2_k127_604853_2 - - - - 0.00000000000000000000000000000000000000000000000000001732 214.0
TH2_k127_604853_3 bacteriocin transport K03561 - - 0.000000000000000000000000007846 119.0
TH2_k127_604853_4 - - - - 0.0000000000000000000000001747 112.0
TH2_k127_604853_5 - - - - 0.000000000000000000004609 109.0
TH2_k127_604853_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000001366 93.0
TH2_k127_604853_7 PBS lyase HEAT-like repeat - - - 0.000000000000008316 89.0
TH2_k127_604853_8 - - - - 0.00000000000004092 80.0
TH2_k127_604853_9 - - - - 0.0000000000001899 83.0
TH2_k127_6051608_0 SMART helicase c2 K03722 - 3.6.4.12 6.446e-200 645.0
TH2_k127_6051608_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000003822 86.0
TH2_k127_6051608_2 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.00000000001517 78.0
TH2_k127_6051608_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669 - - 0.0001954 50.0
TH2_k127_6055029_0 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 407.0
TH2_k127_6055029_1 polysaccharide export K01991,K03088,K20987 - - 0.0000000000000000000000000000000000000005451 164.0
TH2_k127_6068665_0 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 411.0
TH2_k127_6068665_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 329.0
TH2_k127_6068665_2 - - - - 0.00000000000000005785 90.0
TH2_k127_608406_0 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 2.87e-322 1009.0
TH2_k127_608406_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.089e-281 875.0
TH2_k127_608406_10 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000331 252.0
TH2_k127_608406_11 ATPase activity, coupled to transmembrane movement of substances K02118,K02120 - - 0.0000000000000000000000000000000000000000000000000000000000003548 217.0
TH2_k127_608406_12 - - - - 0.000000000000000000000000000000000000000000000000000001705 213.0
TH2_k127_608406_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000000000007316 177.0
TH2_k127_608406_14 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000001426 167.0
TH2_k127_608406_16 - - - - 0.00000005759 63.0
TH2_k127_608406_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 5.36e-199 629.0
TH2_k127_608406_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 465.0
TH2_k127_608406_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 456.0
TH2_k127_608406_5 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 408.0
TH2_k127_608406_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 422.0
TH2_k127_608406_7 Formate/nitrite transporter K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 323.0
TH2_k127_608406_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 310.0
TH2_k127_608406_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009291 287.0
TH2_k127_6087013_0 lipid A export permease ATP-binding protein MsbA K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 459.0
TH2_k127_6087013_1 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000005761 180.0
TH2_k127_6087013_2 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000004754 166.0
TH2_k127_6122667_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001214 255.0
TH2_k127_6122667_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000001162 168.0
TH2_k127_6137768_0 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 330.0
TH2_k127_6137768_1 Belongs to the P(II) protein family - - - 0.000000000000000003376 92.0
TH2_k127_6137768_2 Domain of unknown function (DUF4412) - - - 0.0000000007646 68.0
TH2_k127_6163183_0 - - - - 0.0000000000000000000000000000000001588 140.0
TH2_k127_6163183_1 Competence protein K02238 - - 0.00000000000000000000000004364 121.0
TH2_k127_6173542_0 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 596.0
TH2_k127_6173542_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 585.0
TH2_k127_6173542_10 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 360.0
TH2_k127_6173542_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 293.0
TH2_k127_6173542_12 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003461 258.0
TH2_k127_6173542_13 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000001477 248.0
TH2_k127_6173542_14 PFAM LemA - - - 0.0000000000000000000000000000000000000000000000000000000000000000308 228.0
TH2_k127_6173542_15 Beta-ketoacyl synthase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000001149 195.0
TH2_k127_6173542_16 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.000000000000000000000000000000000000000002074 177.0
TH2_k127_6173542_17 phosphorelay signal transduction system - - - 0.000000000000000000000000000001119 128.0
TH2_k127_6173542_18 response regulator receiver - - - 0.00000000000000000000000000002226 122.0
TH2_k127_6173542_19 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000003928 121.0
TH2_k127_6173542_2 Anticodon binding domain K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 539.0
TH2_k127_6173542_20 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000403 112.0
TH2_k127_6173542_21 Transcription factor zinc-finger K09981 - - 0.000000000000000001001 94.0
TH2_k127_6173542_22 Domain of unknown function (DUF4340) - - - 0.00000000007812 74.0
TH2_k127_6173542_23 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein - - - 0.0000004838 58.0
TH2_k127_6173542_3 His Kinase A (phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 557.0
TH2_k127_6173542_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 463.0
TH2_k127_6173542_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 392.0
TH2_k127_6173542_6 Histidine kinase K01991,K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 386.0
TH2_k127_6173542_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 379.0
TH2_k127_6173542_8 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 363.0
TH2_k127_6173542_9 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 366.0
TH2_k127_6196062_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
TH2_k127_620335_0 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 455.0
TH2_k127_620335_1 cobalamin binding - - - 0.0000000000000000000000000000000000000000000000000000000001769 223.0
TH2_k127_620335_2 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000002579 191.0
TH2_k127_620335_3 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000006021 111.0
TH2_k127_6370156_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 436.0
TH2_k127_6370156_1 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 420.0
TH2_k127_6370156_2 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001096 275.0
TH2_k127_6370156_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002983 257.0
TH2_k127_6440422_0 UDP binding domain K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000002138 241.0
TH2_k127_6440422_1 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000509 247.0
TH2_k127_6503233_0 beta-galactosidase K12111 - 3.2.1.23 0.0 1135.0
TH2_k127_6503233_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.484e-203 649.0
TH2_k127_6503233_10 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 377.0
TH2_k127_6503233_11 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 316.0
TH2_k127_6503233_12 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 318.0
TH2_k127_6503233_13 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004626 240.0
TH2_k127_6503233_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000003402 217.0
TH2_k127_6503233_15 Uncharacterized small protein (DUF2292) - - - 0.0000001286 56.0
TH2_k127_6503233_2 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 479.0
TH2_k127_6503233_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 467.0
TH2_k127_6503233_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 440.0
TH2_k127_6503233_5 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 422.0
TH2_k127_6503233_6 TIGRFAM sulfate ABC transporter, inner membrane subunit CysT K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 398.0
TH2_k127_6503233_7 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 401.0
TH2_k127_6503233_8 Binding-protein-dependent transport system inner membrane component K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 415.0
TH2_k127_6503233_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 399.0
TH2_k127_6514272_0 Heat shock 70 kDa protein K04043 - - 1.862e-290 904.0
TH2_k127_6514272_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.477e-266 828.0
TH2_k127_6514272_10 CBS domain K03699 - - 0.000000000000000000000000000000000000000319 163.0
TH2_k127_6514272_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000008012 145.0
TH2_k127_6514272_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000001697 141.0
TH2_k127_6514272_15 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000001315 83.0
TH2_k127_6514272_16 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000004018 73.0
TH2_k127_6514272_18 Protein of unknown function (DUF433) - - - 0.0000003194 55.0
TH2_k127_6514272_19 Zn-ribbon protein, possibly nucleic acid-binding K07164 - - 0.0000003717 61.0
TH2_k127_6514272_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 400.0
TH2_k127_6514272_20 TIGRFAM PAS sensor protein - - - 0.0000005195 59.0
TH2_k127_6514272_3 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 334.0
TH2_k127_6514272_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 324.0
TH2_k127_6514272_5 typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 323.0
TH2_k127_6514272_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 297.0
TH2_k127_6514272_7 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001019 289.0
TH2_k127_6514272_8 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007856 255.0
TH2_k127_6514272_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000007719 187.0
TH2_k127_6584373_0 FtsX-like permease family K02004 - - 8.208e-215 685.0
TH2_k127_6584373_1 radical SAM domain protein K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 443.0
TH2_k127_6584373_2 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 352.0
TH2_k127_6606439_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 569.0
TH2_k127_6647539_0 Methionine synthase B12-binding module cap domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 310.0
TH2_k127_6647539_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 305.0
TH2_k127_6647539_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 303.0
TH2_k127_6647539_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000001382 239.0
TH2_k127_6647539_4 Outer membrane lipoprotein - - - 0.00000000000000000000000000005043 136.0
TH2_k127_6647539_5 - - - - 0.000000000000000000000002013 111.0
TH2_k127_6647539_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03655,K03892 - 3.6.4.12 0.00000001906 63.0
TH2_k127_6647539_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000003972 54.0
TH2_k127_6730416_0 ATP synthase subunit C K02124 - - 0.00000000000000000001438 93.0
TH2_k127_6730416_1 Product type e enzyme K03427 - 2.1.1.72 0.0000000000000000009838 87.0
TH2_k127_6730416_2 - - - - 0.00000002884 63.0
TH2_k127_6748507_0 Type II IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 549.0
TH2_k127_6748507_1 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 411.0
TH2_k127_6748507_10 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000000000000000000003436 124.0
TH2_k127_6748507_11 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000000000000000000000000005366 115.0
TH2_k127_6748507_12 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000005303 103.0
TH2_k127_6748507_13 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000002572 96.0
TH2_k127_6748507_14 Phosphopantetheine attachment site - - - 0.0000000000000000387 84.0
TH2_k127_6748507_15 glycerol acyltransferase K07003 - - 0.000000000000558 83.0
TH2_k127_6748507_16 - - - - 0.0002252 54.0
TH2_k127_6748507_17 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0007086 50.0
TH2_k127_6748507_2 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
TH2_k127_6748507_3 mannitol metabolic process K00009 - 1.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 327.0
TH2_k127_6748507_4 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007105 293.0
TH2_k127_6748507_5 ATPase MipZ K02282 - - 0.000000000000000000000000000000000000000000000000000000000001032 225.0
TH2_k127_6748507_6 PFAM type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000003681 210.0
TH2_k127_6748507_7 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000008455 207.0
TH2_k127_6748507_8 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000007445 161.0
TH2_k127_6748507_9 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000009324 158.0
TH2_k127_6750289_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.226e-223 705.0
TH2_k127_6750289_1 Amino acid kinase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 459.0
TH2_k127_6750289_10 - - - - 0.000000000000000003616 97.0
TH2_k127_6750289_11 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000006187 89.0
TH2_k127_6750289_12 - - - - 0.0000000000002729 74.0
TH2_k127_6750289_13 CHASE4 domain - - - 0.000000034 65.0
TH2_k127_6750289_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 394.0
TH2_k127_6750289_3 Major Facilitator Superfamily K02445,K07783 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 359.0
TH2_k127_6750289_4 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 293.0
TH2_k127_6750289_5 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000003751 278.0
TH2_k127_6750289_6 Pfam:DUF1498 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005363 236.0
TH2_k127_6750289_7 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.000000000000000000000000000000000000000000000000000000000001225 231.0
TH2_k127_6750289_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000007963 192.0
TH2_k127_6750289_9 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000002417 135.0
TH2_k127_6751006_0 Belongs to the bacterial solute-binding protein 9 family K11604,K11707 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 389.0
TH2_k127_6751006_1 iron dependent repressor K03709 - - 0.0000000000000000000000000003712 117.0
TH2_k127_6760880_0 antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 421.0
TH2_k127_6760880_1 Polycystin cation channel - - - 0.000000000000000000000000000000000000000000000000000000002142 213.0
TH2_k127_6760880_2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000000000000000000006465 127.0
TH2_k127_6769554_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 426.0
TH2_k127_6769554_1 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000574 165.0
TH2_k127_6769554_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000002079 177.0
TH2_k127_6776628_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.816e-311 961.0
TH2_k127_6776628_1 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 328.0
TH2_k127_6776628_2 Domain of unknown function (DUF1768) K09935 - - 0.000000000000000000000000000000000000000000000000000002633 200.0
TH2_k127_6776628_3 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.00000000000000000000000000000000000000000000000001762 207.0
TH2_k127_6776628_4 TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000004088 177.0
TH2_k127_6776628_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000001248 160.0
TH2_k127_6776628_6 Glutathione peroxidase K02199 - - 0.00000000000006796 80.0
TH2_k127_6776628_8 PD-(D/E)XK nuclease superfamily - - - 0.000000004446 70.0
TH2_k127_6776628_9 Psort location Cytoplasmic, score 8.96 - - - 0.00001525 53.0
TH2_k127_6777976_0 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000006918 268.0
TH2_k127_6777976_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000001431 119.0
TH2_k127_6777976_2 Tetratricopeptide repeat - - - 0.0000000000000223 83.0
TH2_k127_6777976_3 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0002645 52.0
TH2_k127_679081_0 COG4206 Outer membrane cobalamin receptor protein K02014,K16092 - - 0.00000000000000000000000000000000000000000000000009465 201.0
TH2_k127_679081_1 - - - - 0.0000000000000000000000000000000000000006162 159.0
TH2_k127_679081_2 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.000000000000000000000000000000000001338 145.0
TH2_k127_679081_3 UTP--glucose-1-phosphate uridylyltransferase - - - 0.0000000000003569 68.0
TH2_k127_679081_4 FES K03575 - - 0.00000003929 59.0
TH2_k127_6793705_0 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 461.0
TH2_k127_6793705_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 372.0
TH2_k127_6793705_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000001431 179.0
TH2_k127_6793705_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000001951 116.0
TH2_k127_6793705_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000002445 95.0
TH2_k127_6793705_5 CRS1_YhbY - - - 0.000000000000000002654 89.0
TH2_k127_6875642_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 2.31e-291 914.0
TH2_k127_6875642_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003938 274.0
TH2_k127_6875642_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000179 203.0
TH2_k127_6875642_3 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000645 162.0
TH2_k127_6875642_4 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000003515 115.0
TH2_k127_6875642_5 - - - - 0.00000000000000000962 90.0
TH2_k127_6882835_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 5.035e-311 964.0
TH2_k127_6882835_1 TonB dependent receptor - - - 1.036e-213 687.0
TH2_k127_6882835_10 methyltransferase - - - 0.00000000000000000000000000000000000004464 153.0
TH2_k127_6882835_11 - - - - 0.000000000000000000000000000000000000819 161.0
TH2_k127_6882835_12 Beta-galactosidase - - - 0.00000000000000000000001513 118.0
TH2_k127_6882835_13 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000003905 95.0
TH2_k127_6882835_14 YceI-like domain - - - 0.00000000000000000004659 98.0
TH2_k127_6882835_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 526.0
TH2_k127_6882835_3 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 511.0
TH2_k127_6882835_4 Ig domain protein group 2 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 434.0
TH2_k127_6882835_5 Chalcone and stilbene synthases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 355.0
TH2_k127_6882835_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 301.0
TH2_k127_6882835_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002085 268.0
TH2_k127_6882835_8 response regulator, receiver K02483,K07665 - - 0.000000000000000000000000000000000000000000000000000000000001567 216.0
TH2_k127_6882835_9 protein histidine kinase activity K02484,K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000214 173.0
TH2_k127_6893494_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1171.0
TH2_k127_6893494_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 9.85e-222 703.0
TH2_k127_6893494_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002385 247.0
TH2_k127_6893494_11 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000002747 239.0
TH2_k127_6893494_12 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000006952 158.0
TH2_k127_6893494_13 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000002666 160.0
TH2_k127_6893494_15 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000002766 137.0
TH2_k127_6893494_16 acetyltransferase - - - 0.000000000000000000000000000000001098 136.0
TH2_k127_6893494_17 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000001844 126.0
TH2_k127_6893494_18 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000224 110.0
TH2_k127_6893494_19 amine dehydrogenase activity - - - 0.0000000000000000000000006604 118.0
TH2_k127_6893494_2 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 505.0
TH2_k127_6893494_20 - - - - 0.0000000000000000000001595 113.0
TH2_k127_6893494_21 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000007121 98.0
TH2_k127_6893494_22 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000003277 102.0
TH2_k127_6893494_23 AraC family transcriptional regulator - - - 0.0000000000000000003518 97.0
TH2_k127_6893494_24 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000573 99.0
TH2_k127_6893494_25 serine-type endopeptidase activity - - - 0.0000000000000000006347 99.0
TH2_k127_6893494_26 - - - - 0.00000000000000001009 89.0
TH2_k127_6893494_27 general secretion pathway protein - - - 0.00000000000000002154 92.0
TH2_k127_6893494_28 Transcription factor zinc-finger K09981 - - 0.000000000000007162 78.0
TH2_k127_6893494_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 348.0
TH2_k127_6893494_30 LysR substrate binding domain K03717 - - 0.00000000001731 72.0
TH2_k127_6893494_31 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000005909 65.0
TH2_k127_6893494_32 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.000000005898 69.0
TH2_k127_6893494_34 - - - - 0.00001864 51.0
TH2_k127_6893494_4 Putative neutral zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 320.0
TH2_k127_6893494_5 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 316.0
TH2_k127_6893494_6 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 293.0
TH2_k127_6893494_7 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 292.0
TH2_k127_6893494_8 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002144 295.0
TH2_k127_6893494_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005866 276.0
TH2_k127_6904672_0 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 394.0
TH2_k127_6904672_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 310.0
TH2_k127_6904672_2 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 308.0
TH2_k127_6904672_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000006268 124.0
TH2_k127_6904672_4 PurA ssDNA and RNA-binding protein - - - 0.0000000000002529 74.0
TH2_k127_6904672_5 response regulator - - - 0.0000001142 63.0
TH2_k127_6914810_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 571.0
TH2_k127_6914810_1 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 556.0
TH2_k127_6914810_10 acyl-CoA dehydrogenase activity K06446 - - 0.0000000000000000000000000000000000001868 166.0
TH2_k127_6914810_11 HAD-hyrolase-like - - - 0.00000000000000000000000000000001133 138.0
TH2_k127_6914810_12 TPR repeat - - - 0.0000000000000000000000001071 119.0
TH2_k127_6914810_13 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000008184 108.0
TH2_k127_6914810_14 Electron transfer flavoprotein FAD-binding domain K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0022904,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000005265 95.0
TH2_k127_6914810_15 - - - - 0.000000004797 58.0
TH2_k127_6914810_16 Ami_3 K01448 - 3.5.1.28 0.0000007023 60.0
TH2_k127_6914810_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 353.0
TH2_k127_6914810_3 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000001056 251.0
TH2_k127_6914810_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000002238 233.0
TH2_k127_6914810_5 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001153 235.0
TH2_k127_6914810_6 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000002799 216.0
TH2_k127_6914810_7 PFAM UvrB UvrC protein K08999,K19411 - - 0.000000000000000000000000000000000000000000000000000335 194.0
TH2_k127_6914810_8 FAD dependent oxidoreductase K00313 - - 0.0000000000000000000000000000000000000000000000001703 206.0
TH2_k127_6914810_9 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000001301 166.0
TH2_k127_6916214_0 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 472.0
TH2_k127_6916214_1 Oxidoreductase K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 466.0
TH2_k127_6916214_2 COG0286 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 393.0
TH2_k127_6916214_3 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 330.0
TH2_k127_6916214_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001337 280.0
TH2_k127_6916214_5 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000004936 196.0
TH2_k127_6916214_6 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000002693 182.0
TH2_k127_6916214_7 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000000000000000000000002889 140.0
TH2_k127_6916214_8 thiolester hydrolase activity K06889 - - 0.00000000000000001431 93.0
TH2_k127_6916214_9 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000916 83.0
TH2_k127_6933094_0 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000001774 188.0
TH2_k127_6933094_1 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000001307 169.0
TH2_k127_6933094_2 PQQ-like domain - - - 0.000000000000000000000000000000000001404 159.0
TH2_k127_6935564_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001716 249.0
TH2_k127_6935564_1 COG4974 Site-specific recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000001348 183.0
TH2_k127_6935564_3 Resolvase - - - 0.00007729 48.0
TH2_k127_6943393_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 577.0
TH2_k127_6943393_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 566.0
TH2_k127_6943393_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 300.0
TH2_k127_6943393_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 297.0
TH2_k127_6943393_12 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000002828 238.0
TH2_k127_6943393_13 PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000001119 227.0
TH2_k127_6943393_14 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000001188 207.0
TH2_k127_6943393_15 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000002181 167.0
TH2_k127_6943393_16 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000001052 146.0
TH2_k127_6943393_17 single-species biofilm formation - - - 0.00000000000000000000000000000000001159 142.0
TH2_k127_6943393_18 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000001082 129.0
TH2_k127_6943393_19 - - - - 0.00000001694 64.0
TH2_k127_6943393_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 555.0
TH2_k127_6943393_3 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 517.0
TH2_k127_6943393_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 440.0
TH2_k127_6943393_5 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 399.0
TH2_k127_6943393_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 379.0
TH2_k127_6943393_7 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 359.0
TH2_k127_6943393_8 Branched-chain amino acid transport system / permease component K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 341.0
TH2_k127_6943393_9 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 315.0
TH2_k127_6958997_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1112.0
TH2_k127_6958997_1 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 414.0
TH2_k127_6958997_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000002465 128.0
TH2_k127_6958997_11 - - - - 0.000000000000000000000003224 117.0
TH2_k127_6958997_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000003802 109.0
TH2_k127_6958997_13 integral membrane protein - - - 0.000005367 59.0
TH2_k127_6958997_2 NAD(P)H-binding K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 389.0
TH2_k127_6958997_3 PFAM GHMP kinase K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 370.0
TH2_k127_6958997_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 307.0
TH2_k127_6958997_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000005491 213.0
TH2_k127_6958997_6 Nucleotidyl transferase K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000003094 216.0
TH2_k127_6958997_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000001395 192.0
TH2_k127_6958997_8 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000001554 175.0
TH2_k127_6958997_9 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000004213 158.0
TH2_k127_6961214_0 FtsX-like permease family - - - 4.566e-226 729.0
TH2_k127_6961214_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 475.0
TH2_k127_6961214_2 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 390.0
TH2_k127_6961214_3 RDD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 280.0
TH2_k127_6961214_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007034 264.0
TH2_k127_6961237_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
TH2_k127_6961237_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000001248 117.0
TH2_k127_6987781_1 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000812 211.0
TH2_k127_6987781_2 - - - - 0.0000000000000000000000000000000000000003004 156.0
TH2_k127_6987781_3 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000005415 141.0
TH2_k127_704640_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000001261 181.0
TH2_k127_704640_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000003844 161.0
TH2_k127_704640_2 methyltransferase activity K00587 - 2.1.1.100 0.0000000000000000000004874 104.0
TH2_k127_704640_3 - - - - 0.00000000000000000178 90.0
TH2_k127_704640_4 PhoQ Sensor - - - 0.0000000002745 73.0
TH2_k127_7068799_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.794e-308 954.0
TH2_k127_7068799_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 391.0
TH2_k127_7068799_10 Type III restriction protein res subunit K01153 - 3.1.21.3 0.000002591 56.0
TH2_k127_7068799_11 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000104 57.0
TH2_k127_7068799_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 352.0
TH2_k127_7068799_3 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 344.0
TH2_k127_7068799_4 glycosyl hydrolase of K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 307.0
TH2_k127_7068799_5 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001704 291.0
TH2_k127_7068799_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000015 231.0
TH2_k127_7068799_7 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.00000000000000004642 87.0
TH2_k127_7068799_8 - - - - 0.0000000002948 64.0
TH2_k127_7089671_0 Required for chromosome condensation and partitioning K03529,K19171 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 525.0
TH2_k127_7089671_1 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 455.0
TH2_k127_7089671_2 Translation initiation factor SUI1 - - - 0.0000000000000000000000000000003074 126.0
TH2_k127_7089671_3 translation release factor activity - - - 0.00000000000007554 79.0
TH2_k127_7089671_4 thioesterase K01075 - - - 0.00000005622 55.0
TH2_k127_7152455_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 419.0
TH2_k127_7152455_1 YdjC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000004062 224.0
TH2_k127_7152455_2 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000002466 160.0
TH2_k127_7197332_0 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 379.0
TH2_k127_7197332_1 radical SAM domain protein - - - 0.00000000000000000000001098 105.0
TH2_k127_7197332_2 Bacterial export proteins, family 1 K02421 - - 0.0000001454 55.0
TH2_k127_7197332_3 glutathione-regulated potassium exporter activity - - - 0.00000223 53.0
TH2_k127_7201959_0 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 526.0
TH2_k127_7201959_1 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 491.0
TH2_k127_7201959_10 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007399 244.0
TH2_k127_7201959_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000003159 222.0
TH2_k127_7201959_12 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000004369 237.0
TH2_k127_7201959_13 PFAM Glycosyl transferase family 2 K09931 - - 0.00000000000000000000000000000000000000000000000000000000000542 215.0
TH2_k127_7201959_14 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000001409 179.0
TH2_k127_7201959_15 amine dehydrogenase activity K21449 - - 0.000000000000000000000000000000000000004016 153.0
TH2_k127_7201959_16 PFAM Alcohol dehydrogenase GroES domain protein, Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000008248 127.0
TH2_k127_7201959_17 alpha beta - - - 0.00000000000000000000008851 109.0
TH2_k127_7201959_18 Cytochrome c3 - - - 0.00000000005363 74.0
TH2_k127_7201959_2 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 479.0
TH2_k127_7201959_3 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 342.0
TH2_k127_7201959_4 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 316.0
TH2_k127_7201959_5 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001283 290.0
TH2_k127_7201959_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001139 278.0
TH2_k127_7201959_7 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001349 274.0
TH2_k127_7201959_8 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006908 276.0
TH2_k127_7201959_9 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000001533 267.0
TH2_k127_7206811_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.244e-229 739.0
TH2_k127_7206811_1 Radical SAM superfamily K06937 - - 2.486e-213 673.0
TH2_k127_7206811_10 tetraacyldisaccharide 4'-kinase activity K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.000000000004048 69.0
TH2_k127_7206811_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 372.0
TH2_k127_7206811_3 Protein of unknown function (DUF3142) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 305.0
TH2_k127_7206811_4 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000408 245.0
TH2_k127_7206811_5 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000000000000000000000000000002332 248.0
TH2_k127_7206811_6 - - - - 0.000000000000000000000000000000000000000000000000285 182.0
TH2_k127_7206811_7 Flagellar basal body rod FlgEFG protein C-terminal - - - 0.00000000000000000000000000000000002456 144.0
TH2_k127_7206811_8 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000002471 145.0
TH2_k127_7206811_9 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000047 85.0
TH2_k127_7206934_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 290.0
TH2_k127_7206934_1 Glycosyltransferase family 36 K00702 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001108 289.0
TH2_k127_7206934_2 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.00000000000000000000000006876 108.0
TH2_k127_7292031_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 548.0
TH2_k127_7292031_1 Putative metal-binding motif - - - 0.00000000000000000000000005266 126.0
TH2_k127_7292031_2 HYR domain K03286 - - 0.00000000000000000001047 108.0
TH2_k127_7330081_0 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 375.0
TH2_k127_7338466_0 COG1233 Phytoene dehydrogenase and related - - - 1.466e-230 726.0
TH2_k127_7338466_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 4.064e-226 711.0
TH2_k127_7338466_10 - - - - 0.0007201 53.0
TH2_k127_7338466_2 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 360.0
TH2_k127_7338466_3 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005836 286.0
TH2_k127_7338466_4 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000201 256.0
TH2_k127_7338466_5 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001143 256.0
TH2_k127_7338466_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000002204 183.0
TH2_k127_7338466_7 Domain of unknown function (DUF4397) - - - 0.00000000000000000000003037 109.0
TH2_k127_7338466_8 helix_turn_helix, arabinose operon control protein K07720 - - 0.00000000001131 66.0
TH2_k127_7338466_9 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00001288 48.0
TH2_k127_734118_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 5.172e-242 762.0
TH2_k127_734118_1 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 577.0
TH2_k127_734118_2 oxidoreductase K19181 - 1.1.1.292 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 394.0
TH2_k127_734118_3 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 359.0
TH2_k127_734118_4 Transposase - - - 0.000000000000000000000000000000000000007561 146.0
TH2_k127_734118_5 ACT domain protein - - - 0.0000000000000000000000000000003277 128.0
TH2_k127_734118_6 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000002687 129.0
TH2_k127_734118_7 Protein of unknown function, DUF481 - - - 0.0000000000001543 80.0
TH2_k127_734118_8 - - - - 0.0000007958 57.0
TH2_k127_7344600_0 PFAM SNF2-related protein K08282 - 2.7.11.1 3.012e-303 958.0
TH2_k127_7344600_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.165e-206 647.0
TH2_k127_7344600_10 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 360.0
TH2_k127_7344600_11 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 313.0
TH2_k127_7344600_12 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 321.0
TH2_k127_7344600_13 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 304.0
TH2_k127_7344600_14 peroxidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 291.0
TH2_k127_7344600_15 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000434 281.0
TH2_k127_7344600_16 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000002479 244.0
TH2_k127_7344600_17 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004233 232.0
TH2_k127_7344600_18 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000001346 222.0
TH2_k127_7344600_19 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000002759 213.0
TH2_k127_7344600_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 601.0
TH2_k127_7344600_20 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000000745 202.0
TH2_k127_7344600_21 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000008141 193.0
TH2_k127_7344600_22 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000006355 191.0
TH2_k127_7344600_23 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000008295 167.0
TH2_k127_7344600_24 - - - - 0.00000000000000000000000000000000000000000002072 173.0
TH2_k127_7344600_25 PFAM Xylose isomerase - - - 0.0000000000000000000000000000000000000000001172 171.0
TH2_k127_7344600_26 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001387 120.0
TH2_k127_7344600_27 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000000000001114 102.0
TH2_k127_7344600_28 YacP-like NYN domain - - - 0.000000000000000000005233 98.0
TH2_k127_7344600_29 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00000000000000000004431 94.0
TH2_k127_7344600_3 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 599.0
TH2_k127_7344600_30 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000001139 81.0
TH2_k127_7344600_31 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000001741 78.0
TH2_k127_7344600_32 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000141 66.0
TH2_k127_7344600_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 468.0
TH2_k127_7344600_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 432.0
TH2_k127_7344600_6 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 429.0
TH2_k127_7344600_7 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 413.0
TH2_k127_7344600_8 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 420.0
TH2_k127_7344600_9 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 363.0
TH2_k127_7391732_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.742e-277 870.0
TH2_k127_7391732_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 3.01e-257 819.0
TH2_k127_7391732_10 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 339.0
TH2_k127_7391732_11 SMART Nucleotide binding protein PINc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 331.0
TH2_k127_7391732_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 321.0
TH2_k127_7391732_13 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 291.0
TH2_k127_7391732_14 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001465 293.0
TH2_k127_7391732_15 PFAM sulfotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005685 278.0
TH2_k127_7391732_16 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000268 273.0
TH2_k127_7391732_17 PFAM Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001399 266.0
TH2_k127_7391732_18 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006489 252.0
TH2_k127_7391732_19 5'-3' exonuclease K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000001602 251.0
TH2_k127_7391732_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 4.456e-239 744.0
TH2_k127_7391732_20 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001101 244.0
TH2_k127_7391732_21 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000001388 231.0
TH2_k127_7391732_22 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003748 235.0
TH2_k127_7391732_23 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000002782 232.0
TH2_k127_7391732_24 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000002404 218.0
TH2_k127_7391732_25 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000009162 211.0
TH2_k127_7391732_26 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000002313 183.0
TH2_k127_7391732_27 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000002137 187.0
TH2_k127_7391732_28 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000000868 159.0
TH2_k127_7391732_29 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000011 149.0
TH2_k127_7391732_3 General secretory system II protein E domain protein K02652 - - 6.834e-213 675.0
TH2_k127_7391732_30 - K07341 - - 0.000000000000000000000000000000009135 135.0
TH2_k127_7391732_31 Lactate utilization protein B C K00782 - - 0.00000000000000000000000000000001447 134.0
TH2_k127_7391732_32 PFAM helix-turn-helix- domain containing protein AraC type K02855 - - 0.00000000000000000000000000000001452 131.0
TH2_k127_7391732_33 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 - - 0.00000000000000000000000000002312 119.0
TH2_k127_7391732_34 Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000005624 121.0
TH2_k127_7391732_35 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000001301 110.0
TH2_k127_7391732_36 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000001212 100.0
TH2_k127_7391732_37 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000004216 87.0
TH2_k127_7391732_39 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000003897 87.0
TH2_k127_7391732_4 General secretory system II protein E domain protein K02454,K02652 - - 1.257e-206 657.0
TH2_k127_7391732_40 Tetratricopeptide repeat - - - 0.00000009334 66.0
TH2_k127_7391732_41 Biopolymer transport protein ExbD/TolR K03559 - - 0.000001283 56.0
TH2_k127_7391732_42 Biopolymer transport protein ExbD/TolR K03559 - - 0.00001498 54.0
TH2_k127_7391732_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.44e-200 634.0
TH2_k127_7391732_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 531.0
TH2_k127_7391732_7 Domain of unknown function (DUF3390) K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 530.0
TH2_k127_7391732_8 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 498.0
TH2_k127_7391732_9 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 486.0
TH2_k127_7392052_0 PFAM ABC transporter related K06158 - - 5.779e-200 641.0
TH2_k127_7392052_1 Met-10+ like-protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 492.0
TH2_k127_7392052_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000008272 158.0
TH2_k127_7392052_11 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000003085 121.0
TH2_k127_7392052_12 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000552 106.0
TH2_k127_7392052_13 KH domain K06960 - - 0.00000000000000000001687 94.0
TH2_k127_7392052_14 amine dehydrogenase activity - - - 0.0000001973 64.0
TH2_k127_7392052_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 482.0
TH2_k127_7392052_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 434.0
TH2_k127_7392052_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 419.0
TH2_k127_7392052_5 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 407.0
TH2_k127_7392052_6 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 293.0
TH2_k127_7392052_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000003731 241.0
TH2_k127_7392052_8 RHS Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000005311 240.0
TH2_k127_7392052_9 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000000000000000001522 226.0
TH2_k127_740907_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 568.0
TH2_k127_740907_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 428.0
TH2_k127_740907_2 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000001728 190.0
TH2_k127_740907_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000004696 117.0
TH2_k127_7503865_0 lipolytic protein G-D-S-L family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 346.0
TH2_k127_7509102_0 Psort location Cytoplasmic, score 7.50 K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 481.0
TH2_k127_7509102_1 Tetratricopeptide repeat - - - 0.00000000000000000000002412 116.0
TH2_k127_7525680_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 415.0
TH2_k127_7525680_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 331.0
TH2_k127_7525680_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000002583 83.0
TH2_k127_7537340_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1105.0
TH2_k127_7537340_1 Glycosyltransferase like family 2 - - - 2.77e-210 684.0
TH2_k127_7537340_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 362.0
TH2_k127_7537340_11 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000001444 224.0
TH2_k127_7537340_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000007544 184.0
TH2_k127_7537340_13 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000004773 188.0
TH2_k127_7537340_14 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.0000000000000000000000000000000000000000000002891 181.0
TH2_k127_7537340_15 ACT domain - - - 0.0000000000000000000000000000000000003873 143.0
TH2_k127_7537340_16 Bifunctional nuclease K08999 - - 0.000000000000000000000000001785 122.0
TH2_k127_7537340_17 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000001403 96.0
TH2_k127_7537340_18 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000003198 87.0
TH2_k127_7537340_19 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000002702 80.0
TH2_k127_7537340_2 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 604.0
TH2_k127_7537340_20 Tetratricopeptide repeat - - - 0.00009677 52.0
TH2_k127_7537340_21 Aminotransferase class-V - - - 0.0002964 44.0
TH2_k127_7537340_3 ABC-type multidrug transport system ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 575.0
TH2_k127_7537340_4 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 442.0
TH2_k127_7537340_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 427.0
TH2_k127_7537340_6 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 411.0
TH2_k127_7537340_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 390.0
TH2_k127_7537340_8 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 371.0
TH2_k127_7537340_9 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 351.0
TH2_k127_7623881_0 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 538.0
TH2_k127_7623881_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 467.0
TH2_k127_7623881_10 Protein of unknown function DUF45 K07043 - - 0.00004934 48.0
TH2_k127_7623881_2 PFAM Carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 459.0
TH2_k127_7623881_3 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 374.0
TH2_k127_7623881_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 313.0
TH2_k127_7623881_5 PFAM Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 314.0
TH2_k127_7623881_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008603 266.0
TH2_k127_7623881_8 - - - - 0.000000000000001906 79.0
TH2_k127_7623881_9 - - - - 0.000000655 53.0
TH2_k127_7683573_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 396.0
TH2_k127_7683573_1 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 312.0
TH2_k127_7683573_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005262 284.0
TH2_k127_7683573_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000101 234.0
TH2_k127_7683573_4 Belongs to the pseudouridine synthase RluA family - - - 0.000000000000000000000000000000000000000000000000000000000000000005887 237.0
TH2_k127_7683573_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000001897 228.0
TH2_k127_7683573_6 TRAP transporter solute receptor TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000001421 207.0
TH2_k127_7683573_7 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000003168 172.0
TH2_k127_7689526_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.589e-275 869.0
TH2_k127_7689526_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 559.0
TH2_k127_7689526_2 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 496.0
TH2_k127_7689526_3 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 457.0
TH2_k127_7689526_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 359.0
TH2_k127_7689526_5 - - - - 0.000000000000000000000000003094 117.0
TH2_k127_7689526_6 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000002328 107.0
TH2_k127_7689526_7 lipoprotein - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00001758 52.0
TH2_k127_7689526_8 Prokaryotic N-terminal methylation motif - - - 0.0009561 48.0
TH2_k127_78033_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 594.0
TH2_k127_78033_1 PFAM Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 397.0
TH2_k127_78033_10 - - - - 0.000000000000000000000000000000000000001781 157.0
TH2_k127_78033_11 Sulfate permease family K03321 - - 0.000000000000000000000000000000002053 132.0
TH2_k127_78033_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000002086 138.0
TH2_k127_78033_13 - - - - 0.00000000000000000000000000000000418 137.0
TH2_k127_78033_14 - - - - 0.000000000000000000000104 107.0
TH2_k127_78033_15 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.000000000000000000434 91.0
TH2_k127_78033_16 serine-type peptidase activity K06978 - - 0.00000000000000003464 96.0
TH2_k127_78033_17 DDE_Tnp_1-associated - - - 0.000000000006163 71.0
TH2_k127_78033_18 Belongs to the peptidase M50B family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000005076 51.0
TH2_k127_78033_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 357.0
TH2_k127_78033_3 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002165 275.0
TH2_k127_78033_4 Transposase IS4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002339 265.0
TH2_k127_78033_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000005486 226.0
TH2_k127_78033_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000001274 226.0
TH2_k127_78033_7 phospho-N-acetylmuramoyl-pentapeptide-transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000001273 220.0
TH2_k127_78033_8 Transposase IS4 family - - - 0.000000000000000000000000000000000000000000000000000000001551 211.0
TH2_k127_78033_9 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000002586 202.0
TH2_k127_7819134_0 molybdopterin cofactor binding - - - 0.0 1524.0
TH2_k127_7819134_1 Squalene-hopene cyclase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 587.0
TH2_k127_7819134_2 Prenyltransferase and squalene oxidase repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 329.0
TH2_k127_7819134_4 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000002109 173.0
TH2_k127_7819134_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001979 62.0
TH2_k127_7819134_6 Psort location CytoplasmicMembrane, score - - - 0.000000002742 70.0
TH2_k127_7825115_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 443.0
TH2_k127_7825115_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 389.0
TH2_k127_7836659_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 608.0
TH2_k127_7836659_1 - - - - 0.00000000000000000000000000001021 122.0
TH2_k127_7838360_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1154.0
TH2_k127_7838360_1 PFAM Xylose isomerase domain protein TIM barrel - - - 3.102e-218 686.0
TH2_k127_7838360_10 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
TH2_k127_7838360_11 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 324.0
TH2_k127_7838360_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003083 274.0
TH2_k127_7838360_13 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005402 279.0
TH2_k127_7838360_14 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000002358 237.0
TH2_k127_7838360_15 PFAM UvrB UvrC protein K19411 - - 0.00000000000000000000000000000000000000000000000193 179.0
TH2_k127_7838360_16 Segregation and condensation complex subunit ScpB - - - 0.000000000000000000000000000000000000000009299 163.0
TH2_k127_7838360_17 - - - - 0.0000000005557 72.0
TH2_k127_7838360_2 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 580.0
TH2_k127_7838360_3 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 547.0
TH2_k127_7838360_4 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 542.0
TH2_k127_7838360_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 528.0
TH2_k127_7838360_6 Protein-arginine kinase K19405 - 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 461.0
TH2_k127_7838360_7 hydrolase, family 3 K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 453.0
TH2_k127_7838360_8 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 399.0
TH2_k127_7838360_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 388.0
TH2_k127_7858687_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 424.0
TH2_k127_7858687_1 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 445.0
TH2_k127_7858687_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002384 265.0
TH2_k127_7858687_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000001645 169.0
TH2_k127_7858687_4 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.000000000000000000000000001047 122.0
TH2_k127_7870252_0 ABC transporter C-terminal domain - - - 1.302e-268 840.0
TH2_k127_7870252_1 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 358.0
TH2_k127_7870252_2 PFAM outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001455 286.0
TH2_k127_7870252_3 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000001708 168.0
TH2_k127_7889120_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000002179 176.0
TH2_k127_7889120_1 COG0822 NifU homolog involved in Fe-S cluster formation K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000003317 146.0
TH2_k127_7889120_2 regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose K02099 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016052,GO:0019219,GO:0019222,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046365,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901575,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000003011 106.0
TH2_k127_7889120_3 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000002224 93.0
TH2_k127_7894348_0 ABC-type sugar transport system periplasmic component K10559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 376.0
TH2_k127_7894348_1 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
TH2_k127_7894348_2 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 274.0
TH2_k127_7894348_3 Belongs to the binding-protein-dependent transport system permease family K10561 - - 0.000000000000000000000000000000000000000000000000000000000000000000008243 248.0
TH2_k127_7894348_4 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000004209 235.0
TH2_k127_7894348_5 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.00000000000000000000000000000000000000000001265 166.0
TH2_k127_7894348_6 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000006146 85.0
TH2_k127_7895846_0 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 479.0
TH2_k127_7895846_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 471.0
TH2_k127_7895846_2 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 417.0
TH2_k127_7895846_3 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002437 279.0
TH2_k127_7895846_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000004305 138.0
TH2_k127_7899452_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1088.0
TH2_k127_7899452_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 9.636e-234 742.0
TH2_k127_7899452_10 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 404.0
TH2_k127_7899452_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 390.0
TH2_k127_7899452_12 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 389.0
TH2_k127_7899452_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 359.0
TH2_k127_7899452_14 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 347.0
TH2_k127_7899452_15 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 314.0
TH2_k127_7899452_16 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 282.0
TH2_k127_7899452_17 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001832 290.0
TH2_k127_7899452_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 272.0
TH2_k127_7899452_19 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001403 267.0
TH2_k127_7899452_2 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 5.132e-223 706.0
TH2_k127_7899452_20 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000001065 268.0
TH2_k127_7899452_21 indole-3-glycerol-phosphate synthase activity K01609,K01696,K13498 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48,4.2.1.20,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000001402 253.0
TH2_k127_7899452_22 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001372 241.0
TH2_k127_7899452_23 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000001996 245.0
TH2_k127_7899452_24 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000009879 229.0
TH2_k127_7899452_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001352 223.0
TH2_k127_7899452_26 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000003574 216.0
TH2_k127_7899452_27 ORF6N domain - - - 0.000000000000000000000000000000000000000000000000000005458 196.0
TH2_k127_7899452_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000005238 197.0
TH2_k127_7899452_29 Phage regulatory protein - - - 0.0000000000000000000000000000000000000000000002546 173.0
TH2_k127_7899452_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 597.0
TH2_k127_7899452_30 ECF sigma factor - - - 0.00000000000000000000000000000000000000741 157.0
TH2_k127_7899452_31 - - - - 0.00000000000000000000000000000000000302 145.0
TH2_k127_7899452_32 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000001913 137.0
TH2_k127_7899452_33 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000002083 136.0
TH2_k127_7899452_34 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000000000002612 130.0
TH2_k127_7899452_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000008694 122.0
TH2_k127_7899452_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000001938 123.0
TH2_k127_7899452_37 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000001415 122.0
TH2_k127_7899452_38 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000004883 119.0
TH2_k127_7899452_39 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000003875 109.0
TH2_k127_7899452_4 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 576.0
TH2_k127_7899452_40 methyltransferase activity - - - 0.0000000000000000000000001023 111.0
TH2_k127_7899452_41 - - - - 0.000000000000375 74.0
TH2_k127_7899452_42 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000165 76.0
TH2_k127_7899452_43 PFAM Tetratricopeptide repeat - - - 0.00000000003252 76.0
TH2_k127_7899452_45 - - - - 0.00002767 51.0
TH2_k127_7899452_5 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 561.0
TH2_k127_7899452_6 Fumarase C C-terminus K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 546.0
TH2_k127_7899452_7 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 530.0
TH2_k127_7899452_8 PFAM ABC transporter related K05816,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 470.0
TH2_k127_7899452_9 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 428.0
TH2_k127_7943935_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.905e-209 661.0
TH2_k127_7943935_1 DNA topoisomerase III K03169 - 5.99.1.2 2.705e-194 630.0
TH2_k127_7943935_10 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.00000001973 62.0
TH2_k127_7943935_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 310.0
TH2_k127_7943935_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001931 264.0
TH2_k127_7943935_4 COG1121 ABC-type Mn Zn transport systems ATPase component K11607,K11710 - - 0.000000000000000000000000000000000000000000000000000000000000001456 227.0
TH2_k127_7943935_5 TIGRFAM cytochrome c nitrate reductase, small subunit K15876 - - 0.000000000000000000000000000000000000000000000000000001408 201.0
TH2_k127_7943935_6 - - - - 0.000000000000000000000000000000005929 133.0
TH2_k127_7943935_7 ABC 3 transport family K09816,K09819 - - 0.00000000000000026 91.0
TH2_k127_7943935_8 FG-GAP repeat - - - 0.0000000000000008005 90.0
TH2_k127_7947679_0 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 1.303e-194 616.0
TH2_k127_7947679_1 polygalacturonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 402.0
TH2_k127_7947679_2 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000006367 245.0
TH2_k127_7992955_0 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000001483 174.0
TH2_k127_7992955_1 3-phosphoshikimate 1-carboxyvinyltransferase activity - - - 0.00000000000000003541 87.0
TH2_k127_7992955_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000003565 57.0
TH2_k127_8002817_0 mannitol 2-dehydrogenase activity K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 569.0
TH2_k127_8002817_1 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 514.0
TH2_k127_8002817_2 Band 7 protein K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 377.0
TH2_k127_8002817_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 346.0
TH2_k127_8002817_4 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 289.0
TH2_k127_8002817_5 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000000001198 161.0
TH2_k127_8002817_6 YMGG-like Gly-zipper - - - 0.0000000000000000000000000002914 121.0
TH2_k127_8002817_7 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000694 102.0
TH2_k127_806677_0 Lysine-2,3-aminomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 563.0
TH2_k127_806677_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 349.0
TH2_k127_806677_10 Auxin Efflux Carrier K07088 - - 0.000000000000000001543 97.0
TH2_k127_806677_2 Glutamyl-tRNAGlu reductase, N-terminal domain K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001622 296.0
TH2_k127_806677_3 TIGRFAM ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000003683 220.0
TH2_k127_806677_4 Porphobilinogen deaminase, dipyromethane cofactor binding domain K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000011 206.0
TH2_k127_806677_5 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000001167 158.0
TH2_k127_806677_6 - - - - 0.0000000000000000000000000000000000004148 151.0
TH2_k127_806677_7 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000578 145.0
TH2_k127_806677_8 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000123 120.0
TH2_k127_806677_9 - - - - 0.0000000000000000001118 99.0
TH2_k127_8137815_0 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0 1506.0
TH2_k127_8137815_1 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 348.0
TH2_k127_8137815_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000237 250.0
TH2_k127_8162153_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003905 280.0
TH2_k127_8162153_1 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000003913 164.0
TH2_k127_8162153_2 Belongs to the ompA family - - - 0.0000000000000000000000000000677 136.0
TH2_k127_8162153_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000005085 66.0
TH2_k127_8193631_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 465.0
TH2_k127_8193631_1 histidinol dehydrogenase activity K00013,K15509 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 373.0
TH2_k127_8193631_10 - - - - 0.00000000000000000000806 95.0
TH2_k127_8193631_11 integral membrane protein - - - 0.000000000000002454 89.0
TH2_k127_8193631_12 Domain of unknown function (DUF4339) - - - 0.000000000000003265 88.0
TH2_k127_8193631_13 - - - - 0.000000002747 69.0
TH2_k127_8193631_14 general secretion pathway protein - - - 0.000000006634 59.0
TH2_k127_8193631_2 Domain of unknown function (DUF4129) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 370.0
TH2_k127_8193631_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 318.0
TH2_k127_8193631_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000008614 246.0
TH2_k127_8193631_5 histone acetyltransferase binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000005835 244.0
TH2_k127_8193631_6 - - - - 0.0000000000000000000000000000000001424 140.0
TH2_k127_8193631_7 Oxidoreductase FAD-binding domain K21832 - - 0.000000000000000000000000000000858 138.0
TH2_k127_8193631_8 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000001166 100.0
TH2_k127_8193631_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000002688 100.0
TH2_k127_8219585_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 599.0
TH2_k127_8219585_1 Bacterial regulatory protein, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 480.0
TH2_k127_8219585_10 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000727 174.0
TH2_k127_8219585_11 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000004228 166.0
TH2_k127_8219585_12 Galactose oxidase, central domain - - - 0.00000000000000000000000000000000000005587 165.0
TH2_k127_8219585_13 - K07092 - - 0.000000000000000000000000000000000001214 148.0
TH2_k127_8219585_14 methylamine metabolic process - - - 0.000000000000000000000000000009217 124.0
TH2_k127_8219585_16 PFAM Rhodanese domain protein - - - 0.000000000000000000000009336 106.0
TH2_k127_8219585_17 Protein of unknown function (DUF4230) - - - 0.00000000000000000000006415 107.0
TH2_k127_8219585_18 CAAX protease self-immunity K07052 - - 0.0000000000000000008073 98.0
TH2_k127_8219585_19 COG1214 Inactive homolog of metal-dependent proteases K14742 - - 0.00000000000000000919 92.0
TH2_k127_8219585_2 Poly A polymerase head domain K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 475.0
TH2_k127_8219585_20 Protein of unknown function (DUF1573) - - - 0.00000000000004906 84.0
TH2_k127_8219585_21 S-layer homology domain - - - 0.0000000003061 74.0
TH2_k127_8219585_22 Universal stress protein - - - 0.0000006251 57.0
TH2_k127_8219585_23 Pfam:DUF59 - - - 0.0001032 45.0
TH2_k127_8219585_24 Domain of unknown function DUF302 - - - 0.0001677 48.0
TH2_k127_8219585_3 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 378.0
TH2_k127_8219585_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000007982 245.0
TH2_k127_8219585_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001949 195.0
TH2_k127_8219585_6 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000007298 179.0
TH2_k127_8219585_7 Pfam:DUF59 - - - 0.000000000000000000000000000000000000000000005305 171.0
TH2_k127_8219585_8 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000003566 158.0
TH2_k127_8219585_9 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000000000000008516 158.0
TH2_k127_8229341_0 Domain of unknown function (DUF4914) - - - 1.034e-276 867.0
TH2_k127_8229341_1 - K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 489.0
TH2_k127_8229341_10 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 300.0
TH2_k127_8229341_11 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 287.0
TH2_k127_8229341_12 PFAM Short-chain dehydrogenase reductase SDR K00068 - 1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000001011 258.0
TH2_k127_8229341_13 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004339 262.0
TH2_k127_8229341_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000005379 212.0
TH2_k127_8229341_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000002515 193.0
TH2_k127_8229341_16 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000002438 168.0
TH2_k127_8229341_17 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000002062 165.0
TH2_k127_8229341_18 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000002216 162.0
TH2_k127_8229341_19 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000003891 151.0
TH2_k127_8229341_2 Alcohol dehydrogenase GroES-like domain K19956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 479.0
TH2_k127_8229341_20 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000129 128.0
TH2_k127_8229341_21 - - - - 0.000000000000000000000003004 108.0
TH2_k127_8229341_22 - - - - 0.000000000000000003452 92.0
TH2_k127_8229341_23 AraC-like ligand binding domain - - - 0.000000000000001555 87.0
TH2_k127_8229341_24 GTPase subunit of restriction endonuclease K07452 - - 0.0000000162 59.0
TH2_k127_8229341_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 441.0
TH2_k127_8229341_4 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 377.0
TH2_k127_8229341_5 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 358.0
TH2_k127_8229341_6 Belongs to the glycosyl hydrolase 28 family K01213 - 3.2.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 350.0
TH2_k127_8229341_7 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 346.0
TH2_k127_8229341_8 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 336.0
TH2_k127_8229341_9 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 304.0
TH2_k127_8247702_0 glutamate synthase K00284 - 1.4.7.1 0.0 2179.0
TH2_k127_8247702_1 ThiC-associated domain K03147 - 4.1.99.17 0.0 1028.0
TH2_k127_8247702_2 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 5.636e-261 821.0
TH2_k127_8247702_3 COG0583 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 308.0
TH2_k127_8247702_4 lipoprotein transporter activity K02003,K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006865 283.0
TH2_k127_8247702_5 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000004637 125.0
TH2_k127_8290906_0 TonB-dependent receptor K02014 - - 4.379e-199 642.0
TH2_k127_8290906_1 xylulokinase activity K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 512.0
TH2_k127_8290906_10 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000001647 132.0
TH2_k127_8290906_11 - - - - 0.0000000000000000000000000005866 119.0
TH2_k127_8290906_12 regulation of translation K03530 - - 0.000000000000000000000001056 106.0
TH2_k127_8290906_13 Domain of unknown function (DUF4154) - - - 0.0000000000000000106 90.0
TH2_k127_8290906_15 - - - - 0.000000000000256 77.0
TH2_k127_8290906_16 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000001015 64.0
TH2_k127_8290906_17 - - - - 0.0000003245 57.0
TH2_k127_8290906_18 type II restriction enzyme, methylase - - - 0.000009512 55.0
TH2_k127_8290906_19 WYL domain - - - 0.0003156 48.0
TH2_k127_8290906_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 353.0
TH2_k127_8290906_20 Membrane - - - 0.0006531 51.0
TH2_k127_8290906_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 320.0
TH2_k127_8290906_4 DNA modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 311.0
TH2_k127_8290906_5 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000006742 231.0
TH2_k127_8290906_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000003458 193.0
TH2_k127_8290906_7 hydrolase K07025 - - 0.00000000000000000000000000000000000000000000465 181.0
TH2_k127_8290906_8 COG1002 Type II restriction enzyme, methylase subunits - - - 0.000000000000000000000000000000000001289 155.0
TH2_k127_8290906_9 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000002732 138.0
TH2_k127_8317577_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1113.0
TH2_k127_8317577_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 286.0
TH2_k127_8317577_11 Heavy-metal resistance - - - 0.000105 52.0
TH2_k127_8317577_12 general secretion pathway protein K02456 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0008796 48.0
TH2_k127_8317577_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002561 266.0
TH2_k127_8317577_3 PFAM type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005677 260.0
TH2_k127_8317577_4 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000148 154.0
TH2_k127_8317577_5 Pilus assembly protein PilX - - - 0.000000000000000000000000000000002841 145.0
TH2_k127_8317577_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000002328 139.0
TH2_k127_8317577_7 - - - - 0.0000000000000000000000000002941 121.0
TH2_k127_8317577_8 general secretion pathway protein - - - 0.000000000002034 71.0
TH2_k127_8317577_9 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000001679 63.0
TH2_k127_8346905_0 SNF2 family N-terminal domain - - - 8.127e-216 702.0
TH2_k127_8346905_1 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 611.0
TH2_k127_8346905_10 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 357.0
TH2_k127_8346905_11 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 312.0
TH2_k127_8346905_12 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008868 277.0
TH2_k127_8346905_13 PFAM mannose-6-phosphate isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000005415 267.0
TH2_k127_8346905_14 Tetratricopeptide repeat - - - 0.0000000000000000000002743 99.0
TH2_k127_8346905_15 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0003259 51.0
TH2_k127_8346905_2 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 635.0
TH2_k127_8346905_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 586.0
TH2_k127_8346905_4 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 574.0
TH2_k127_8346905_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 494.0
TH2_k127_8346905_6 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 429.0
TH2_k127_8346905_7 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 389.0
TH2_k127_8346905_8 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 394.0
TH2_k127_8346905_9 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 361.0
TH2_k127_8348562_0 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 1.395e-210 665.0
TH2_k127_8348562_1 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 443.0
TH2_k127_8348562_2 PFAM TspO MBR family K05770 - - 0.000000000000000000000000000000000000000000000000002785 186.0
TH2_k127_8348562_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.000000000000000000000000000000000007574 140.0
TH2_k127_8361394_0 beta-galactosidase K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 579.0
TH2_k127_8361394_1 Coagulation factor 5 8 type domain protein K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 422.0
TH2_k127_8361394_2 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 348.0
TH2_k127_8361394_3 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 303.0
TH2_k127_8361394_4 PFAM Glycoside hydrolase, clan GH-D - - - 0.000000000000000000000000000000000000000000000000004298 203.0
TH2_k127_8361394_5 glycosyl hydrolase of K09955 - - 0.0000000000000000000000000000002361 143.0
TH2_k127_8361394_6 Glycoside hydrolase 97 K01187 - 3.2.1.20 0.00000000000000003407 96.0
TH2_k127_8361394_7 COG1520 FOG WD40-like repeat - - - 0.00000003559 66.0
TH2_k127_8361394_8 - - - - 0.000002773 61.0
TH2_k127_8361394_9 WD40-like repeat - - - 0.00001538 59.0
TH2_k127_8379668_0 Ras family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001552 262.0
TH2_k127_8379668_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000004271 160.0
TH2_k127_8379668_2 Roadblock/LC7 domain - - - 0.000000000000001715 83.0
TH2_k127_8379668_3 Competence protein ComEA K02237 - - 0.0006981 51.0
TH2_k127_8385130_0 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 1.449e-203 642.0
TH2_k127_8385130_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 338.0
TH2_k127_8385130_2 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 306.0
TH2_k127_8385130_3 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000008573 258.0
TH2_k127_8385130_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000009249 255.0
TH2_k127_8385130_5 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000523 198.0
TH2_k127_8416767_0 - - - - 0.0000000000001107 81.0
TH2_k127_8416767_1 FtsX-like permease family - - - 0.000000000002821 81.0
TH2_k127_8455228_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 2.298e-246 771.0
TH2_k127_8455228_1 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 456.0
TH2_k127_8455228_2 PFAM L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 274.0
TH2_k127_8455228_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000002699 225.0
TH2_k127_8455228_4 helix_turn_helix, arabinose operon control protein K21826 - - 0.000000000000000000000000000000000000000000000000000001063 202.0
TH2_k127_8455228_5 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K00477 - 1.14.11.18 0.00000000000000000000000000000000000000000001404 173.0
TH2_k127_8455228_6 Pterin binding enzyme K00548 - 2.1.1.13 0.00000000000000000000000000000163 133.0
TH2_k127_8455228_7 - - - - 0.00000000000000001143 85.0
TH2_k127_8468550_0 TonB-dependent receptor K02014 - - 1.052e-214 687.0
TH2_k127_8468550_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 507.0
TH2_k127_8468550_2 secondary active sulfate transmembrane transporter activity K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 481.0
TH2_k127_8468550_3 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000006794 123.0
TH2_k127_8474086_0 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000002817 80.0
TH2_k127_8496354_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 376.0
TH2_k127_8496354_1 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009089 284.0
TH2_k127_8496354_2 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006294 270.0
TH2_k127_8496354_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000003737 206.0
TH2_k127_8496354_4 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000002299 184.0
TH2_k127_8496354_5 Melibiase K07407 - 3.2.1.22 0.0003697 53.0
TH2_k127_8531893_0 PFAM Stage II sporulation E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 294.0
TH2_k127_8531893_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000006951 221.0
TH2_k127_8531893_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000003301 190.0
TH2_k127_8531893_4 ATP-independent chaperone mediated protein folding K06006 - - 0.000000000008074 72.0
TH2_k127_8531893_5 - - - - 0.00000003183 56.0
TH2_k127_8531893_6 - - - - 0.000001994 61.0
TH2_k127_8531893_7 - - - - 0.00006446 52.0
TH2_k127_8537904_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009492 390.0
TH2_k127_8537904_1 His Kinase A (phosphoacceptor) domain K00694,K03406,K07315,K14986 - 2.4.1.12,2.7.13.3,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 332.0
TH2_k127_8537904_2 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005259 285.0
TH2_k127_8537904_3 Aldose 1-epimerase K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009883 273.0
TH2_k127_8537904_4 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000129 148.0
TH2_k127_8537904_5 PFAM plasmid - - - 0.0000000000000000002293 91.0
TH2_k127_8537904_7 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0005346 44.0
TH2_k127_8551135_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 377.0
TH2_k127_8551135_1 HYR domain - - - 0.0000000000000000000000000000000000000002477 164.0
TH2_k127_8551135_2 - - - - 0.000000000000000003327 90.0
TH2_k127_8556074_0 DEAD DEAH box helicase domain protein K05592 - 3.6.4.13 8.362e-195 623.0
TH2_k127_8556074_1 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000006447 226.0
TH2_k127_8556074_2 Domain of unknown function (DUF4338) - - - 0.00000000002268 68.0
TH2_k127_8618970_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.23e-245 771.0
TH2_k127_8618970_1 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 2.186e-200 641.0
TH2_k127_8618970_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002753 267.0
TH2_k127_8618970_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000008491 224.0
TH2_k127_8618970_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000003538 196.0
TH2_k127_8618970_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000004462 182.0
TH2_k127_8618970_6 PFAM AhpC TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000002671 161.0
TH2_k127_8618970_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000308 112.0
TH2_k127_8633357_0 PFAM Radical SAM K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 479.0
TH2_k127_8633357_1 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002211 260.0
TH2_k127_8633357_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000001003 239.0
TH2_k127_8633357_3 - - - - 0.000000000000000000000000000000000000000000001397 175.0
TH2_k127_8633357_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000003744 163.0
TH2_k127_8633357_5 ABC transporter K01990 - - 0.0001479 46.0
TH2_k127_86425_0 NAD synthase - - - 8.587e-197 636.0
TH2_k127_86425_1 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 432.0
TH2_k127_86425_2 COG3250 Beta-galactosidase beta-glucuronidase K01195 - 3.2.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 354.0
TH2_k127_86425_3 FHA domain - - - 0.0000000000000000000000000000000000000000000000000001598 197.0
TH2_k127_86425_4 Pseudouridine synthase K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000002069 179.0
TH2_k127_86425_5 Major Facilitator Superfamily - - - 0.0000000000000002334 92.0
TH2_k127_86425_6 Transposase IS200 like K07491 - - 0.00000000004885 65.0
TH2_k127_86425_7 Transcription factor zinc-finger - - - 0.0000006117 58.0
TH2_k127_86425_8 tetratricopeptide repeat - - - 0.0003212 53.0
TH2_k127_8746104_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000275 174.0
TH2_k127_8746104_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000001417 154.0
TH2_k127_8794205_0 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 542.0
TH2_k127_8794205_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 431.0
TH2_k127_8794205_10 Uncharacterized protein conserved in bacteria (DUF2064) K09931,K20742 - 3.4.14.13 0.000000000000000000000000000001165 130.0
TH2_k127_8794205_11 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000007472 110.0
TH2_k127_8794205_12 alpha beta alpha domain I - - - 0.000000000000000002314 90.0
TH2_k127_8794205_2 ResB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 314.0
TH2_k127_8794205_3 PHP domain K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000004039 250.0
TH2_k127_8794205_4 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000008595 246.0
TH2_k127_8794205_5 acr, cog1565 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004146 253.0
TH2_k127_8794205_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000002926 221.0
TH2_k127_8794205_7 - - - - 0.000000000000000000000000000000000000000000000005073 185.0
TH2_k127_8794205_8 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000004017 162.0
TH2_k127_8794205_9 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02504,K02652 - - 0.000000000000000000000000000000003941 133.0
TH2_k127_8802785_0 PFAM peptidase M16 domain protein K07263 - - 2.826e-231 751.0
TH2_k127_8802785_1 - - - - 0.0000000000000000000000000000000000000003523 156.0
TH2_k127_8802785_3 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00001745 50.0
TH2_k127_8825168_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 363.0
TH2_k127_8825168_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000003611 191.0
TH2_k127_8880584_0 carbohydrate binding K00702 - 2.4.1.20 0.0000000000000000000000000000000001223 143.0
TH2_k127_8880584_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102,K11103 - - 0.000004001 54.0
TH2_k127_8900183_0 Holliday junction DNA helicase ruvB N-terminus K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 546.0
TH2_k127_90846_0 Glycosyl hydrolase family 57 K16149 - 2.4.1.18 6.269e-212 672.0
TH2_k127_90846_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 373.0
TH2_k127_90846_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001086 251.0
TH2_k127_90846_3 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000004472 229.0
TH2_k127_90846_4 Domain of unknown function (DUF4912) K09942 - - 0.000000000000000000000000000000000000000453 166.0
TH2_k127_91940_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 512.0
TH2_k127_91940_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 472.0
TH2_k127_91940_2 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 293.0
TH2_k127_91940_3 Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000002486 204.0
TH2_k127_91940_4 Preprotein translocase subunit K03210 - - 0.000000000000001451 79.0
TH2_k127_91940_5 Domain of unknown function (DUF4115) - - - 0.00000000000001083 81.0
TH2_k127_95854_0 ATP-dependent helicase C-terminal K03579 - 3.6.4.13 0.0 1045.0
TH2_k127_95854_1 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 611.0
TH2_k127_95854_10 beta-galactosidase activity K01190,K01219,K12308 - 3.2.1.23,3.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000002118 275.0
TH2_k127_95854_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005074 275.0
TH2_k127_95854_12 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000000001532 236.0
TH2_k127_95854_13 - - - - 0.0000000000000000000000000000000000000000000000000000000002264 209.0
TH2_k127_95854_14 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000006318 206.0
TH2_k127_95854_15 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000009574 189.0
TH2_k127_95854_16 DNA topological change - - - 0.00000000000000000000000000000000000000000000003067 175.0
TH2_k127_95854_17 - - - - 0.0000000000000000000000000000000000000000005658 182.0
TH2_k127_95854_18 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000006402 148.0
TH2_k127_95854_19 bacteriocin transport K03561 - - 0.00000000000000000000000000000000000008982 152.0
TH2_k127_95854_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 485.0
TH2_k127_95854_20 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000007335 155.0
TH2_k127_95854_22 PBS lyase HEAT-like repeat - - - 0.00000000000000000000009484 115.0
TH2_k127_95854_23 - - - - 0.0000000000000001275 95.0
TH2_k127_95854_24 - - - - 0.0000000000000002133 87.0
TH2_k127_95854_25 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000004548 83.0
TH2_k127_95854_27 - - - - 0.000000000001737 74.0
TH2_k127_95854_28 - - - - 0.00000001018 68.0
TH2_k127_95854_29 PQQ-like domain - - - 0.000001014 63.0
TH2_k127_95854_3 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 411.0
TH2_k127_95854_30 peptidyl-tyrosine sulfation - - - 0.000001014 63.0
TH2_k127_95854_32 fumarate reductase K00239 - 1.3.5.1,1.3.5.4 0.000033 56.0
TH2_k127_95854_4 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 359.0
TH2_k127_95854_5 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 346.0
TH2_k127_95854_6 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
TH2_k127_95854_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 317.0
TH2_k127_95854_8 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003464 278.0
TH2_k127_95854_9 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004573 292.0