logo

Overview

ID MAG03984
Name TLS2_bin.13
Sample SMP0104
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Bryobacterales
Family Bryobacteraceae
Genus JAWXCM01
Species
Assembly information
Completeness (%) 86.59
Contamination (%) 5.34
GC content (%) 61.0
N50 (bp) 6,447
Genome size (bp) 6,972,744

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes6231

Gene name Description KEGG GOs EC E-value Score Sequence
TLS2_k127_100375_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.871e-243 759.0
TLS2_k127_100375_1 Ribosomal_S15 K02956 - - 0.000000000000000000000000000001235 123.0
TLS2_k127_1021148_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 464.0
TLS2_k127_1021148_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 358.0
TLS2_k127_1021148_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000399 282.0
TLS2_k127_1021148_3 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000002924 256.0
TLS2_k127_1021148_4 recA bacterial DNA recombination protein - - - 0.0000000000000000000000000000000000000000001003 167.0
TLS2_k127_1021148_5 Tetratricopeptide repeat - - - 0.00000000000000000001344 101.0
TLS2_k127_1023744_0 glycolate transport K14393 - - 1.431e-266 828.0
TLS2_k127_1023744_1 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 494.0
TLS2_k127_1023744_10 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000000000000000000872 132.0
TLS2_k127_1023744_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000002538 132.0
TLS2_k127_1023744_12 Helix-turn-helix domain - - - 0.0000000000000000000009772 97.0
TLS2_k127_1023744_13 Alpha beta hydrolase - - - 0.000000000000001277 81.0
TLS2_k127_1023744_14 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000001999 76.0
TLS2_k127_1023744_15 domain protein - - - 0.0000000000000749 80.0
TLS2_k127_1023744_16 alpha/beta hydrolase fold - - - 0.000000002655 60.0
TLS2_k127_1023744_2 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 394.0
TLS2_k127_1023744_3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 317.0
TLS2_k127_1023744_4 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003278 282.0
TLS2_k127_1023744_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002963 253.0
TLS2_k127_1023744_6 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000008189 247.0
TLS2_k127_1023744_7 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000000000000000000005885 168.0
TLS2_k127_1023744_8 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000001054 159.0
TLS2_k127_1023744_9 - - - - 0.000000000000000000000000000000000001412 154.0
TLS2_k127_1024658_0 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 432.0
TLS2_k127_1024658_1 Transposase - - - 0.000000000000000000000000000000000000000000004274 164.0
TLS2_k127_1024658_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000001125 86.0
TLS2_k127_1024658_3 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000005577 83.0
TLS2_k127_1041212_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 7.521e-220 707.0
TLS2_k127_1041212_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000002244 226.0
TLS2_k127_1041212_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000009792 164.0
TLS2_k127_1041212_4 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000159 166.0
TLS2_k127_1041212_5 PFAM Peptidase family S58 - - - 0.00000000000000000000000000003598 121.0
TLS2_k127_1041212_6 - - - - 0.0000000000000000000007465 106.0
TLS2_k127_1061060_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.157e-195 628.0
TLS2_k127_1061060_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 456.0
TLS2_k127_1061060_2 Two component transcriptional regulator, winged helix family K07776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 338.0
TLS2_k127_1061060_3 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 328.0
TLS2_k127_1061060_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000871 273.0
TLS2_k127_1061060_5 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000009415 190.0
TLS2_k127_1061060_6 - - - - 0.00000000000000000000000000000000000000000000005348 177.0
TLS2_k127_1061060_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.0000000000315 68.0
TLS2_k127_106258_0 Asparagine synthase K01953 - 6.3.5.4 4.555e-287 896.0
TLS2_k127_106258_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 456.0
TLS2_k127_106258_2 protein methyltransferase activity K02687 - - 0.000000000000000000000000000000000000000001594 166.0
TLS2_k127_106258_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000002121 87.0
TLS2_k127_106258_4 Belongs to the peptidase S8 family K03561,K12287,K20276 - - 0.000000000002725 76.0
TLS2_k127_106258_5 Polymerase - - - 0.000000001147 71.0
TLS2_k127_1064903_0 Maltogenic Amylase, C-terminal domain K01187 - 3.2.1.20 1.247e-226 713.0
TLS2_k127_1074851_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 554.0
TLS2_k127_1074851_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 371.0
TLS2_k127_1074851_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 338.0
TLS2_k127_1074851_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0000000000000000002199 95.0
TLS2_k127_1074851_4 Belongs to the MraZ family K03925 - - 0.00000000000001113 78.0
TLS2_k127_1083892_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000001876 195.0
TLS2_k127_1083892_1 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000000002897 152.0
TLS2_k127_1083892_2 Belongs to the sigma-70 factor family K03088 - - 0.00000000000004866 77.0
TLS2_k127_1085529_0 SAF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 428.0
TLS2_k127_1085529_1 PFAM carbohydrate kinase K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 366.0
TLS2_k127_1085529_2 L-fucose isomerase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 338.0
TLS2_k127_1085529_3 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001055 281.0
TLS2_k127_1085529_4 Putative esterase - - - 0.00000000000000000000000000000000000005884 157.0
TLS2_k127_1085529_5 PFAM Sugar isomerase (SIS) K06041 - 5.3.1.13 0.0000000000000000000000000000000000007706 148.0
TLS2_k127_1085529_6 AraC family transcriptional regulator - - - 0.00000000000000000000000003979 120.0
TLS2_k127_1086813_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 391.0
TLS2_k127_1086813_1 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 300.0
TLS2_k127_1086813_2 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000001653 153.0
TLS2_k127_1086813_3 Methyltransferase - - - 0.000000000000000000000000000002184 121.0
TLS2_k127_1092215_0 Metalloenzyme superfamily K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 391.0
TLS2_k127_1092215_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000002345 221.0
TLS2_k127_109863_0 MacB-like periplasmic core domain - - - 1.611e-206 668.0
TLS2_k127_109863_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 333.0
TLS2_k127_109863_2 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000008231 226.0
TLS2_k127_1103002_0 - - - - 0.00000000000000000002905 93.0
TLS2_k127_1103002_2 bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding - - - 0.0000000006081 67.0
TLS2_k127_1103002_3 bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding - - - 0.0004424 45.0
TLS2_k127_1103372_0 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000003217 201.0
TLS2_k127_1103372_2 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000001282 115.0
TLS2_k127_1115893_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 612.0
TLS2_k127_1117202_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 556.0
TLS2_k127_1117202_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 368.0
TLS2_k127_1117202_2 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003488 245.0
TLS2_k127_1117202_3 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000004265 233.0
TLS2_k127_1124991_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 374.0
TLS2_k127_1124991_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000136 146.0
TLS2_k127_1135209_0 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 568.0
TLS2_k127_1135209_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 282.0
TLS2_k127_1135209_2 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006593 248.0
TLS2_k127_1135209_3 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001078 222.0
TLS2_k127_1135209_4 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000001413 206.0
TLS2_k127_1135209_5 - - - - 0.00000000000000000000000000000000000000000000000009458 192.0
TLS2_k127_1135209_6 PFAM FAD linked oxidase domain protein K11472 - - 0.0000000000000000000008426 104.0
TLS2_k127_1135209_7 peroxidase - - - 0.000001117 52.0
TLS2_k127_1137863_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 8.432e-260 822.0
TLS2_k127_1137863_1 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 587.0
TLS2_k127_1137863_2 Ku70/Ku80 beta-barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 355.0
TLS2_k127_1137863_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004131 284.0
TLS2_k127_1137863_4 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003297 247.0
TLS2_k127_1137863_5 - - - - 0.0000000000000000000000000000009957 124.0
TLS2_k127_1138812_0 response regulator K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 375.0
TLS2_k127_1138812_1 Transposase domain (DUF772) K07487 - - 0.00000000000000000000000000000000000000000000000000000000004204 213.0
TLS2_k127_1138812_2 Protein of unknown function (DUF3303) - - - 0.000000000000000000000000000003988 121.0
TLS2_k127_1138812_3 Transposase domain (DUF772) K07487 - - 0.00000000000001656 77.0
TLS2_k127_1138812_4 Transposase domain (DUF772) K07487 - - 0.000000000001529 73.0
TLS2_k127_1140440_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 6.624e-210 660.0
TLS2_k127_1140440_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000506 250.0
TLS2_k127_1140440_2 - - - - 0.0000000000000000000000000000000000000000000000000000313 196.0
TLS2_k127_114548_0 Tripartite tricarboxylate transporter TctA K07793 - - 3.243e-200 634.0
TLS2_k127_114548_1 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 556.0
TLS2_k127_114548_2 Chase2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000003447 222.0
TLS2_k127_114548_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000006694 228.0
TLS2_k127_114548_4 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000000000000000000000001521 209.0
TLS2_k127_114548_5 DNA-binding transcription factor activity K06075 - - 0.00000000000000000000000000000000003898 140.0
TLS2_k127_114548_6 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000001321 94.0
TLS2_k127_1155672_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 396.0
TLS2_k127_1155672_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000005961 235.0
TLS2_k127_1155672_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000002741 197.0
TLS2_k127_1155672_3 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000002444 185.0
TLS2_k127_1155672_4 Yqey-like protein K09117 - - 0.00000000000000000000000005457 113.0
TLS2_k127_116138_0 Purple acid Phosphatase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 475.0
TLS2_k127_116138_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000007469 205.0
TLS2_k127_116138_2 PQQ-like domain - - - 0.000000000000000000000001256 111.0
TLS2_k127_116138_3 Putative regulatory protein - - - 0.00000000000136 70.0
TLS2_k127_1165158_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1149.0
TLS2_k127_1165158_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503,K13950 - 2.6.1.85,4.1.3.27 0.0 1019.0
TLS2_k127_1165158_10 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000008238 233.0
TLS2_k127_1165158_11 pyrroloquinoline quinone binding K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000004164 206.0
TLS2_k127_1165158_12 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000133 170.0
TLS2_k127_1165158_14 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000038 108.0
TLS2_k127_1165158_15 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000006793 104.0
TLS2_k127_1165158_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.599e-299 929.0
TLS2_k127_1165158_3 all-trans-retinol 13,14-reductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.592e-222 700.0
TLS2_k127_1165158_4 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 500.0
TLS2_k127_1165158_5 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 434.0
TLS2_k127_1165158_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 420.0
TLS2_k127_1165158_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 363.0
TLS2_k127_1165158_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 337.0
TLS2_k127_1165158_9 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 289.0
TLS2_k127_1169140_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 602.0
TLS2_k127_1169140_1 zinc ion binding K02347,K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 544.0
TLS2_k127_1169140_2 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 364.0
TLS2_k127_1169140_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
TLS2_k127_1169140_4 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000257 224.0
TLS2_k127_1169140_5 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000001143 196.0
TLS2_k127_1169140_6 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000893 162.0
TLS2_k127_1172444_0 TonB-dependent receptor - - - 2.37e-233 741.0
TLS2_k127_1174777_0 Transposase domain (DUF772) K07487 - - 0.0000000000000000000000000000000000000000000000000000000000000002791 230.0
TLS2_k127_1174777_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000002319 109.0
TLS2_k127_1174777_2 - - - - 0.0000000000000000000008417 96.0
TLS2_k127_1174777_3 - - - - 0.00000000009533 64.0
TLS2_k127_1174777_4 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000001254 58.0
TLS2_k127_1174777_5 - K21495 - - 0.00000002919 59.0
TLS2_k127_1174777_6 and related - - - 0.00002848 47.0
TLS2_k127_1186326_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 505.0
TLS2_k127_1186326_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000008041 238.0
TLS2_k127_1229349_0 Concanavalin A-like lectin/glucanases superfamily - - - 3.375e-317 999.0
TLS2_k127_1229349_1 Protein of unknown function (DUF1501) - - - 3.917e-230 724.0
TLS2_k127_1229349_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 298.0
TLS2_k127_1239532_0 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000002098 171.0
TLS2_k127_1239532_1 signal transduction protein with a C-terminal ATPase domain K02478,K08082 - 2.7.13.3 0.0000000000000000000005107 109.0
TLS2_k127_1239532_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.000001007 54.0
TLS2_k127_1239532_3 PFAM Penicillin binding protein transpeptidase domain - - - 0.00003146 52.0
TLS2_k127_1243810_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000961 182.0
TLS2_k127_124484_0 deoxyhypusine monooxygenase activity K08884 - 2.7.11.1 0.0 1602.0
TLS2_k127_124484_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 532.0
TLS2_k127_124484_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 465.0
TLS2_k127_124484_3 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 413.0
TLS2_k127_124484_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 364.0
TLS2_k127_124484_5 PFAM FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 344.0
TLS2_k127_124484_6 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 279.0
TLS2_k127_124484_7 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000009179 261.0
TLS2_k127_124484_8 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000001445 242.0
TLS2_k127_125117_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1098.0
TLS2_k127_125117_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.017e-249 777.0
TLS2_k127_125117_2 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 533.0
TLS2_k127_125117_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 337.0
TLS2_k127_125117_4 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 316.0
TLS2_k127_125117_5 photoreceptor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003426 242.0
TLS2_k127_125117_6 phosphorelay signal transduction system - - - 0.000000000000000000000003087 109.0
TLS2_k127_1260387_0 Histidine kinase internal region K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 472.0
TLS2_k127_1260387_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 442.0
TLS2_k127_1260387_2 MOSC domain containing protein K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 317.0
TLS2_k127_1260387_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 305.0
TLS2_k127_1260387_4 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001594 289.0
TLS2_k127_1260387_6 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000004818 104.0
TLS2_k127_1260387_7 Domain of unknown function (DUF4440) - - - 0.0000000000000000000473 94.0
TLS2_k127_1260387_8 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000005736 87.0
TLS2_k127_126804_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 354.0
TLS2_k127_126804_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000247 102.0
TLS2_k127_126804_2 alpha beta - - - 0.000000000000000000003435 105.0
TLS2_k127_1272792_0 PFAM Integrase catalytic - - - 5.65e-199 631.0
TLS2_k127_1272792_1 ParB-like nuclease domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 511.0
TLS2_k127_1272792_3 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000001354 162.0
TLS2_k127_1272792_5 Phage integrase family - - - 0.0000000000000000000000000000002356 125.0
TLS2_k127_1272792_6 Plasmid encoded RepA protein - - - 0.00000000000000000002488 91.0
TLS2_k127_1281287_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 415.0
TLS2_k127_1281287_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 349.0
TLS2_k127_1281287_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000002367 169.0
TLS2_k127_1281287_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000003614 98.0
TLS2_k127_1281485_0 Aminotransferase class I and II K14261 - - 2.954e-203 643.0
TLS2_k127_1281485_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 6.141e-194 618.0
TLS2_k127_1281485_2 RNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007016 237.0
TLS2_k127_1281485_3 GAF domain - - - 0.000000000000000000000000005332 119.0
TLS2_k127_1281485_4 hyperosmotic response - - - 0.00000000000000000000003394 108.0
TLS2_k127_1281485_5 CarboxypepD_reg-like domain - - - 0.000005963 57.0
TLS2_k127_1282658_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 8.836e-241 752.0
TLS2_k127_1282658_1 - - - - 7.267e-207 665.0
TLS2_k127_1282658_2 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 396.0
TLS2_k127_1282658_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000003834 206.0
TLS2_k127_1282658_4 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.0000000000000000000000000000000002467 136.0
TLS2_k127_1282658_5 Smr domain - - - 0.00000000000000000000000000002674 129.0
TLS2_k127_1282658_6 4-alpha-glucanotransferase K00700,K00705,K02438,K06044 - 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 0.0000000000000004479 80.0
TLS2_k127_1282658_7 PFAM short chain dehydrogenase K00046,K00065,K18009 - 1.1.1.127,1.1.1.304,1.1.1.69,1.1.1.76 0.000000001964 59.0
TLS2_k127_1282658_8 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000002141 53.0
TLS2_k127_1284247_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 335.0
TLS2_k127_1284247_1 4Fe-4S dicluster domain K07307 - - 0.00000000000000000000000000000000000001837 150.0
TLS2_k127_1290090_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 573.0
TLS2_k127_1290090_1 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 464.0
TLS2_k127_1290090_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 476.0
TLS2_k127_1290090_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001341 289.0
TLS2_k127_1290090_4 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000001087 236.0
TLS2_k127_1290090_5 - - - - 0.0000000000000000000000000000000000000000000002172 173.0
TLS2_k127_1290090_6 PFAM regulatory protein, ArsR K21903 - - 0.000000000000000000000000002275 119.0
TLS2_k127_1309776_0 Peptidase S46 - - - 6.717e-213 679.0
TLS2_k127_1309776_1 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 388.0
TLS2_k127_1309776_2 cellulose binding - - - 0.000000000000000000000000008375 128.0
TLS2_k127_1309776_3 cell adhesion involved in biofilm formation K07004,K12132 - 2.7.11.1 0.00000000000000000000003414 117.0
TLS2_k127_1309776_4 membrane protein of uknown function UCP014873 - - - 0.00000000000000000002377 100.0
TLS2_k127_1309776_5 amine dehydrogenase activity - - - 0.000000000006618 79.0
TLS2_k127_1309776_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0003237 50.0
TLS2_k127_1310818_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 407.0
TLS2_k127_1310818_1 homoserine dehydrogenase activity K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 388.0
TLS2_k127_1310818_2 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 342.0
TLS2_k127_1310818_3 Met-10+ like-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003639 248.0
TLS2_k127_1310818_4 amine dehydrogenase activity K14647,K21449 - - 0.000000000000000000000000000000000000000000000000000000000000004837 229.0
TLS2_k127_1310818_5 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000006324 215.0
TLS2_k127_1310818_6 - - - - 0.00000000000000000000000007608 117.0
TLS2_k127_1310818_8 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000002494 72.0
TLS2_k127_1314965_0 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 1.556e-293 920.0
TLS2_k127_1314965_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 330.0
TLS2_k127_1314965_2 NikR C terminal nickel binding domain K07722 - - 0.000000000000000000000000000000000000000000000000000001555 194.0
TLS2_k127_1314965_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000007392 176.0
TLS2_k127_1314965_5 Cell wall formation K00075 - 1.3.1.98 0.0001847 45.0
TLS2_k127_1320711_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 332.0
TLS2_k127_1320711_1 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000258 253.0
TLS2_k127_1320711_2 Acetyltransferase (GNAT) domain K22479 - - 0.00000000000000000000000000000000000000000000000000000000284 207.0
TLS2_k127_1320711_3 Protein conserved in bacteria - - - 0.0000000000000000000009207 98.0
TLS2_k127_1320711_4 - - - - 0.0000001173 63.0
TLS2_k127_1330987_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 7.642e-281 870.0
TLS2_k127_1330987_1 Cytochrome c, class I - - - 3.431e-250 792.0
TLS2_k127_1330987_10 BON domain - - - 0.00000000000000000000000000000000000000000007836 166.0
TLS2_k127_1330987_11 Rnk N-terminus K06140 - - 0.0000000000000000000000000000002993 127.0
TLS2_k127_1330987_13 Universal stress protein - - - 0.00001129 57.0
TLS2_k127_1330987_2 Protein of unknown function (DUF1501) - - - 3.701e-248 771.0
TLS2_k127_1330987_3 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 564.0
TLS2_k127_1330987_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 430.0
TLS2_k127_1330987_5 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 434.0
TLS2_k127_1330987_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 376.0
TLS2_k127_1330987_7 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 280.0
TLS2_k127_1330987_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005656 255.0
TLS2_k127_1330987_9 Cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000001292 247.0
TLS2_k127_133327_0 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001777 239.0
TLS2_k127_133327_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000009634 186.0
TLS2_k127_133327_2 Cupin 2, conserved barrel domain protein - - - 0.00000000002573 71.0
TLS2_k127_1334091_0 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 560.0
TLS2_k127_1334091_1 PFAM sigma-54 factor interaction domain-containing protein K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 452.0
TLS2_k127_1334091_2 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 364.0
TLS2_k127_1334091_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000006461 70.0
TLS2_k127_133517_0 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 3.082e-220 693.0
TLS2_k127_133517_1 COG3119 Arylsulfatase A K01565 - 3.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 428.0
TLS2_k127_133517_2 YtxH-like protein - - - 0.000000000000711 72.0
TLS2_k127_1339372_0 Domain of unknown function (DUF5060) - - - 3.879e-249 781.0
TLS2_k127_1339372_1 Protein of unknown function (DUF4038) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007576 268.0
TLS2_k127_1339372_2 Protein of unknown function (DUF1593) - - - 0.0000000000000000005435 88.0
TLS2_k127_134826_0 Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 582.0
TLS2_k127_134826_1 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 419.0
TLS2_k127_134826_2 PFAM Resolvase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 322.0
TLS2_k127_134826_3 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.00000000000000000000000000000000000000000000000000000000001334 211.0
TLS2_k127_134826_4 Calcium binding - - - 0.0000000000000000000000000000000000000000004918 160.0
TLS2_k127_134826_5 IS66 Orf2 like protein K07484 - - 0.00000000000000000000000000000000000000001866 161.0
TLS2_k127_134826_6 - - - - 0.000000000000000000000000008046 126.0
TLS2_k127_134826_7 - - - - 0.00000000000006467 77.0
TLS2_k127_1348755_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 423.0
TLS2_k127_1359267_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000008601 181.0
TLS2_k127_1359267_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000003607 148.0
TLS2_k127_1359267_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000636 142.0
TLS2_k127_1359267_3 Transposase and inactivated derivatives K00986,K07497 - 2.7.7.49 0.00000000003904 65.0
TLS2_k127_1359267_4 Transposase - - - 0.0004557 49.0
TLS2_k127_1362720_0 BNR repeat-like domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 611.0
TLS2_k127_1362720_1 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 359.0
TLS2_k127_1363923_0 photoreceptor activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 581.0
TLS2_k127_1363923_1 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 285.0
TLS2_k127_1363923_2 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000973 275.0
TLS2_k127_1363923_3 HWE histidine kinase - - - 0.0000000000000000000000000000000000709 156.0
TLS2_k127_1363923_4 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000139 141.0
TLS2_k127_1364373_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 377.0
TLS2_k127_1364373_1 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 386.0
TLS2_k127_1364373_2 region 4 type 2 K03088 - - 0.0000000000000000000000000000000000000002118 158.0
TLS2_k127_1364936_0 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000004142 256.0
TLS2_k127_1364936_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000001473 124.0
TLS2_k127_1364936_2 Domain of unknown function (DUF697) K06883 - - 0.000000000000000000000005637 104.0
TLS2_k127_1364936_3 Domain of unknown function (DUF697) K06883 - - 0.0000000000223 74.0
TLS2_k127_1368352_0 penicillin-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 398.0
TLS2_k127_1368352_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 371.0
TLS2_k127_1368352_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 316.0
TLS2_k127_1368352_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000001244 205.0
TLS2_k127_1368352_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000003729 126.0
TLS2_k127_1373948_0 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 505.0
TLS2_k127_1373948_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 319.0
TLS2_k127_1373948_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000008073 257.0
TLS2_k127_1373948_3 permease K03548 - - 0.0000000000000002084 85.0
TLS2_k127_1384248_0 anaphase-promoting complex binding - - - 4.291e-289 898.0
TLS2_k127_1384248_1 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 1.308e-282 880.0
TLS2_k127_1384248_2 Protein of unknown function (DUF1501) - - - 1.076e-260 808.0
TLS2_k127_1384248_3 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000002106 94.0
TLS2_k127_1388320_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.816e-236 769.0
TLS2_k127_1388320_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 595.0
TLS2_k127_1388320_10 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 359.0
TLS2_k127_1388320_11 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 367.0
TLS2_k127_1388320_12 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 290.0
TLS2_k127_1388320_13 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007084 286.0
TLS2_k127_1388320_14 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 276.0
TLS2_k127_1388320_15 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000007888 267.0
TLS2_k127_1388320_16 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003784 270.0
TLS2_k127_1388320_17 Class II Aldolase and Adducin N-terminal domain K22130 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.1.104 0.0000000000000000000000000000000000000000000000005263 190.0
TLS2_k127_1388320_18 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000006302 176.0
TLS2_k127_1388320_19 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000002713 166.0
TLS2_k127_1388320_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 542.0
TLS2_k127_1388320_20 HD domain - - - 0.000000000000000000000000001854 117.0
TLS2_k127_1388320_21 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000482 84.0
TLS2_k127_1388320_22 Protein of unknown function (DUF2934) - - - 0.00000000003281 69.0
TLS2_k127_1388320_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 467.0
TLS2_k127_1388320_4 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 425.0
TLS2_k127_1388320_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 391.0
TLS2_k127_1388320_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 386.0
TLS2_k127_1388320_8 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 385.0
TLS2_k127_1388320_9 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 381.0
TLS2_k127_1405180_0 Pfam Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 302.0
TLS2_k127_1405180_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000001656 193.0
TLS2_k127_1405180_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000187 169.0
TLS2_k127_1405180_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000001256 92.0
TLS2_k127_1410848_0 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000001616 237.0
TLS2_k127_1410848_1 Domain of Unknown Function (DUF350) - - - 0.000000000000000000000000000000000000000000001411 175.0
TLS2_k127_1417200_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.228e-258 836.0
TLS2_k127_1417200_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 417.0
TLS2_k127_1417200_2 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006997 259.0
TLS2_k127_1417200_3 Transmembrane secretion effector - - - 0.000000000000000000000002205 106.0
TLS2_k127_1420592_0 hmm pf01609 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006382 248.0
TLS2_k127_1420592_1 Histidine kinase - - - 0.00000000000000000000000000002159 120.0
TLS2_k127_1420592_2 Immunity protein 32 - - - 0.0000004804 57.0
TLS2_k127_1420592_3 Zinc metalloprotease (Elastase) K01400,K01417,K01448,K20274 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.4.24.28,3.5.1.28 0.00000272 54.0
TLS2_k127_1423430_0 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 353.0
TLS2_k127_1423430_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006634 249.0
TLS2_k127_1423430_2 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000005936 238.0
TLS2_k127_1423430_3 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000000000000000000000000486 204.0
TLS2_k127_1423430_4 PFAM glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000004108 192.0
TLS2_k127_1423430_5 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000001432 135.0
TLS2_k127_1423430_6 - - - - 0.00000000002151 64.0
TLS2_k127_144029_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
TLS2_k127_144029_1 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000005964 243.0
TLS2_k127_144029_2 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000001221 223.0
TLS2_k127_1441927_0 ABC-type sugar transport systems permease components K02025,K10193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 499.0
TLS2_k127_1441927_1 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 404.0
TLS2_k127_1441927_2 ABC-type sugar transport system, permease component K10194 - - 0.000000000000000000000000000000000000000000000000000000000002064 211.0
TLS2_k127_1441927_3 Thij pfpi - - - 0.00000000000000000000004912 100.0
TLS2_k127_144950_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 362.0
TLS2_k127_1449601_0 Carboxypeptidase regulatory-like domain - - - 0.0 1338.0
TLS2_k127_1449601_1 PFAM Peptidase S41 K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000004642 198.0
TLS2_k127_1453866_0 PFAM Integrase catalytic - - - 3.131e-195 621.0
TLS2_k127_1453866_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 426.0
TLS2_k127_1453866_3 Protein of unknown function (DUF561) K00459 - 1.13.12.16 0.000000000000649 68.0
TLS2_k127_1453866_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K13525 - - 0.000000000002452 69.0
TLS2_k127_1454841_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 565.0
TLS2_k127_146294_0 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 327.0
TLS2_k127_146294_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000009365 235.0
TLS2_k127_1463904_0 Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 544.0
TLS2_k127_1463904_1 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 329.0
TLS2_k127_1463904_2 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001477 243.0
TLS2_k127_1474957_0 COG1233 Phytoene dehydrogenase and related - - - 1.966e-213 681.0
TLS2_k127_1474957_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 439.0
TLS2_k127_1474957_10 oxidation-reduction process - - - 0.000000000008427 71.0
TLS2_k127_1474957_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 370.0
TLS2_k127_1474957_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 356.0
TLS2_k127_1474957_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 297.0
TLS2_k127_1474957_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002318 265.0
TLS2_k127_1474957_6 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000012 239.0
TLS2_k127_1474957_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000004393 198.0
TLS2_k127_1474957_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000001252 192.0
TLS2_k127_1474957_9 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000001602 139.0
TLS2_k127_1477315_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 300.0
TLS2_k127_1477315_1 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000004951 167.0
TLS2_k127_1488362_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 347.0
TLS2_k127_1488362_1 Pfam Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 256.0
TLS2_k127_1488362_2 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000001632 163.0
TLS2_k127_1488362_3 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000002831 53.0
TLS2_k127_1492008_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 552.0
TLS2_k127_1492008_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 293.0
TLS2_k127_1492008_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002884 279.0
TLS2_k127_1492008_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007269 261.0
TLS2_k127_1492008_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001465 261.0
TLS2_k127_1492008_5 COG3321 Polyketide synthase modules and related proteins K04786,K13613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000655 258.0
TLS2_k127_1492008_6 Methyltransferase domain K16215 - 2.1.1.243 0.000000000000000002971 97.0
TLS2_k127_1492008_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000001408 90.0
TLS2_k127_1510420_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 351.0
TLS2_k127_1510420_1 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003803 248.0
TLS2_k127_1510420_2 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000001175 242.0
TLS2_k127_1514751_0 Arylsulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 610.0
TLS2_k127_1514751_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 545.0
TLS2_k127_1514751_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 444.0
TLS2_k127_1514751_3 - - - - 0.00000000000000000000000000000000316 134.0
TLS2_k127_1519999_0 Belongs to the xylose isomerase family K01805 - 5.3.1.5 5.19e-202 634.0
TLS2_k127_1519999_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 437.0
TLS2_k127_1519999_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 397.0
TLS2_k127_1519999_3 aldo keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 381.0
TLS2_k127_1519999_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000711 241.0
TLS2_k127_1519999_5 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000001001 211.0
TLS2_k127_1519999_6 Protein of unknown function (DUF2905) - - - 0.0000000000000000634 82.0
TLS2_k127_1537589_0 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 492.0
TLS2_k127_1537589_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000988 135.0
TLS2_k127_1540040_0 domain protein K20276 - - 0.000000000000000000000000000000000000000000000000000000003657 224.0
TLS2_k127_1540040_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000007011 123.0
TLS2_k127_1540040_2 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000009371 117.0
TLS2_k127_1540040_3 Belongs to the 'phage' integrase family - - - 0.00000000000000001892 83.0
TLS2_k127_1540040_4 Protein of unknown function (DUF2793) - - - 0.00000000002229 72.0
TLS2_k127_1541074_0 COG0380 Trehalose-6-phosphate synthase K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 589.0
TLS2_k127_1541074_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 328.0
TLS2_k127_1541074_2 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000001256 195.0
TLS2_k127_1541074_3 protein kinase activity - - - 0.000000000000000001218 92.0
TLS2_k127_1541074_4 - - - - 0.000000002055 68.0
TLS2_k127_1541074_5 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases - - - 0.00001995 59.0
TLS2_k127_1543776_0 peptidoglycan glycosyltransferase activity K03588,K05364,K05837 GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.0 1131.0
TLS2_k127_1543776_1 Bestrophin, RFP-TM, chloride channel K08994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 357.0
TLS2_k127_1543776_2 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 322.0
TLS2_k127_1543776_3 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001846 261.0
TLS2_k127_1543776_4 histone H2A K63-linked ubiquitination K02283 - - 0.00000000000000000000000000001314 130.0
TLS2_k127_1543776_5 Universal stress protein family - - - 0.00000000000000000000002966 110.0
TLS2_k127_1551792_0 Glycosyl hydrolases family 2 K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 617.0
TLS2_k127_1551792_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 482.0
TLS2_k127_1551792_2 Sulfatase K01565 - 3.10.1.1 0.00000089 51.0
TLS2_k127_1552113_0 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006893 243.0
TLS2_k127_1552113_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000007016 232.0
TLS2_k127_1552113_2 Disulphide bond corrector protein DsbC K04084,K06888 - 1.8.1.8 0.00000000000000000000000000001422 123.0
TLS2_k127_1559894_0 HipA N-terminal domain K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 562.0
TLS2_k127_1559894_1 DNA polymerase LigD, ligase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 305.0
TLS2_k127_1559894_2 Helix-turn-helix domain - - - 0.00000000000000001196 85.0
TLS2_k127_1559894_3 heat shock protein binding K09503 - - 0.0002383 48.0
TLS2_k127_1568792_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 498.0
TLS2_k127_1568792_1 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 305.0
TLS2_k127_1568792_2 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000002919 84.0
TLS2_k127_1576279_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 7.9e-228 711.0
TLS2_k127_1576279_1 Belongs to the TPP enzyme family K01652 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 448.0
TLS2_k127_1576279_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002671 268.0
TLS2_k127_1576279_3 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000005829 190.0
TLS2_k127_1576279_4 - - - - 0.000000000000000000000000002241 124.0
TLS2_k127_157746_0 Protein of unknown function (DUF1549) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 499.0
TLS2_k127_157746_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003904 275.0
TLS2_k127_15846_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 421.0
TLS2_k127_15846_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 338.0
TLS2_k127_15846_2 Biotin-requiring enzyme - - - 0.0000000000000000168 86.0
TLS2_k127_160679_0 tail sheath protein - - - 0.000000000000000000005272 107.0
TLS2_k127_160679_1 FRG - - - 0.000000000000006708 79.0
TLS2_k127_1607587_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 590.0
TLS2_k127_1607587_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 518.0
TLS2_k127_1607587_2 PFAM peptidase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 446.0
TLS2_k127_1607587_3 - - - - 0.00000001867 65.0
TLS2_k127_160839_0 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 557.0
TLS2_k127_160839_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 319.0
TLS2_k127_160839_2 Elongation factor P K02356 - - 0.000000000000000000000000000008876 126.0
TLS2_k127_1614737_0 sodium:proton antiporter activity K06382 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 383.0
TLS2_k127_1614737_1 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000003965 165.0
TLS2_k127_1614737_2 helicase superfamily c-terminal domain K03732 - 3.6.4.13 0.0000000000000008464 78.0
TLS2_k127_1625259_0 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 557.0
TLS2_k127_1625259_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 422.0
TLS2_k127_1625259_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 417.0
TLS2_k127_1625259_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 330.0
TLS2_k127_162887_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 415.0
TLS2_k127_162887_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 402.0
TLS2_k127_162887_2 PFAM response regulator receiver K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 324.0
TLS2_k127_162887_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001571 239.0
TLS2_k127_162887_4 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000008353 136.0
TLS2_k127_162887_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000001029 125.0
TLS2_k127_1629576_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 2.475e-215 680.0
TLS2_k127_1629576_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 391.0
TLS2_k127_1629576_2 Protein-arginine deiminase (PAD) K01481 - 3.5.3.15 0.000000000000000000000000000000000000000000000000000007502 215.0
TLS2_k127_1629576_3 Peptidoglycan-binding domain 1 protein K01447,K07126,K13582 - 3.5.1.28 0.000000000000000000000000000000000000000000003292 172.0
TLS2_k127_1629576_4 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000001503 126.0
TLS2_k127_1629576_5 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000006308 119.0
TLS2_k127_1629576_6 deoxyhypusine monooxygenase activity - - - 0.0000004994 61.0
TLS2_k127_1631557_0 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 7.1e-308 958.0
TLS2_k127_1631557_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.359e-218 685.0
TLS2_k127_1631557_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 555.0
TLS2_k127_1631557_3 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003933 246.0
TLS2_k127_1631557_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000002094 207.0
TLS2_k127_1631557_5 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000002373 201.0
TLS2_k127_1631557_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000002857 153.0
TLS2_k127_1631650_0 PFAM Glycosyl transferase family 2 - - - 2.816e-248 777.0
TLS2_k127_1631650_1 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 581.0
TLS2_k127_1631650_2 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000003518 195.0
TLS2_k127_1631650_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000001433 113.0
TLS2_k127_1631650_4 - - - - 0.000000122 59.0
TLS2_k127_1632948_0 TonB-dependent receptor - - - 4.457e-201 664.0
TLS2_k127_1632948_1 ABC transporter transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 383.0
TLS2_k127_1633702_0 cytochrome C - - - 4.691e-242 764.0
TLS2_k127_1633702_1 Protein of unknown function (DUF1501) - - - 7.526e-197 622.0
TLS2_k127_1633859_0 Peptidase C39 family K12541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 522.0
TLS2_k127_1633859_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 434.0
TLS2_k127_1633859_10 - - - - 0.0000000000000000000000000000002725 139.0
TLS2_k127_1633859_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000001695 118.0
TLS2_k127_1633859_12 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K03525 - 2.7.1.33 0.00000000001801 70.0
TLS2_k127_1633859_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 432.0
TLS2_k127_1633859_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 401.0
TLS2_k127_1633859_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 379.0
TLS2_k127_1633859_5 Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 371.0
TLS2_k127_1633859_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 332.0
TLS2_k127_1633859_7 Alanine dehydrogenase/PNT, C-terminal domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 325.0
TLS2_k127_1633859_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004258 289.0
TLS2_k127_1633859_9 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000106 238.0
TLS2_k127_1640279_0 protocatechuate 3,4-dioxygenase activity - - - 0.0 1521.0
TLS2_k127_1640279_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.411e-270 842.0
TLS2_k127_1640279_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 7.898e-217 693.0
TLS2_k127_1640279_3 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 299.0
TLS2_k127_1640279_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
TLS2_k127_1640279_5 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000000000000000001611 239.0
TLS2_k127_1640279_6 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000001059 175.0
TLS2_k127_1640279_7 PFAM Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000162 137.0
TLS2_k127_1640643_0 Plasmid encoded RepA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 427.0
TLS2_k127_1640643_1 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000001202 225.0
TLS2_k127_1640643_2 PIN domain - - - 0.00000000000000000000000000004218 120.0
TLS2_k127_1640643_3 PFAM transposase IS116 IS110 IS902 family - - - 0.00002798 48.0
TLS2_k127_1644741_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.242e-239 747.0
TLS2_k127_1644741_1 chlorophyll binding - - - 4.59e-217 709.0
TLS2_k127_1644741_10 cheY-homologous receiver domain - - - 0.00000000000000000001209 96.0
TLS2_k127_1644741_11 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006482,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0008214,GO:0008984,GO:0009605,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0018277,GO:0019538,GO:0019899,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051723,GO:0052689,GO:0070988,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1990827 3.1.1.61,3.5.1.44 0.000000000000003525 77.0
TLS2_k127_1644741_12 - - - - 0.00000000002448 68.0
TLS2_k127_1644741_13 40-residue YVTN family beta-propeller repeat - - - 0.0000000001438 76.0
TLS2_k127_1644741_2 ABC transporter K06147 - - 7.965e-208 655.0
TLS2_k127_1644741_3 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 610.0
TLS2_k127_1644741_4 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 490.0
TLS2_k127_1644741_5 MgtE intracellular - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 486.0
TLS2_k127_1644741_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003388 290.0
TLS2_k127_1644741_7 - - - - 0.000000000000000000000000000000000000000000000000000000000442 211.0
TLS2_k127_1644741_8 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000005858 151.0
TLS2_k127_1650795_0 Glycosyl hydrolases family 2, TIM barrel domain - - - 2.571e-225 712.0
TLS2_k127_1650795_1 Class V aminotransferase K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 403.0
TLS2_k127_1650795_2 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000001263 195.0
TLS2_k127_1650795_3 cheY-homologous receiver domain K02485 - - 0.0000000000000000000000000000000000002013 147.0
TLS2_k127_1653753_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002513 272.0
TLS2_k127_1653753_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000002177 180.0
TLS2_k127_1653753_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000009257 120.0
TLS2_k127_1654658_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 4.88e-212 667.0
TLS2_k127_1654658_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 544.0
TLS2_k127_1654658_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 512.0
TLS2_k127_1654658_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 452.0
TLS2_k127_1654658_4 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 434.0
TLS2_k127_1654658_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 389.0
TLS2_k127_1654658_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 301.0
TLS2_k127_1654984_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 400.0
TLS2_k127_1654984_1 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 287.0
TLS2_k127_1654984_2 PFAM secretion protein HlyD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005538 258.0
TLS2_k127_1654984_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000008156 155.0
TLS2_k127_1654984_4 TIGRFAM amino acid adenylation domain - - - 0.000000000002172 72.0
TLS2_k127_1656888_0 transport - - - 3.965e-316 1003.0
TLS2_k127_1656888_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 520.0
TLS2_k127_1656888_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 341.0
TLS2_k127_1656888_3 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 292.0
TLS2_k127_1656888_4 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008398 239.0
TLS2_k127_1656888_5 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000000000000000000000004187 209.0
TLS2_k127_166295_0 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 464.0
TLS2_k127_166295_1 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 465.0
TLS2_k127_1666734_0 Carboxypeptidase regulatory-like domain - - - 1.461e-218 704.0
TLS2_k127_166807_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 1.021e-239 760.0
TLS2_k127_166807_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.685e-208 663.0
TLS2_k127_166807_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 422.0
TLS2_k127_1674184_0 PFAM AMP-dependent synthetase and ligase K12429,K18660,K18661,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 444.0
TLS2_k127_1674184_1 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000171 149.0
TLS2_k127_1678735_0 non-ribosomal peptide synthetase - - - 0.0 1056.0
TLS2_k127_1678735_1 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 3.55e-237 770.0
TLS2_k127_168306_0 AcrB/AcrD/AcrF family - - - 0.0 1415.0
TLS2_k127_168306_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 413.0
TLS2_k127_168306_2 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 329.0
TLS2_k127_168306_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000009052 225.0
TLS2_k127_168306_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000001736 94.0
TLS2_k127_168819_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 383.0
TLS2_k127_168819_1 OsmC-like protein - - - 0.0000000000009939 70.0
TLS2_k127_1703383_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.099e-265 839.0
TLS2_k127_1703383_1 deoxyhypusine monooxygenase activity K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 455.0
TLS2_k127_1703383_2 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 450.0
TLS2_k127_1703383_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000001529 168.0
TLS2_k127_1703383_4 Haem-degrading - - - 0.00000000000000000000000000000000000000003004 157.0
TLS2_k127_1703383_5 Transcriptional regulator - - - 0.000000000000000000000000000000000009987 144.0
TLS2_k127_1718267_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 598.0
TLS2_k127_1718267_1 HTH-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 427.0
TLS2_k127_1718267_2 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000008635 98.0
TLS2_k127_1718267_3 transposase activity - - - 0.00000000000008889 72.0
TLS2_k127_1718267_4 - - - - 0.0000000003406 62.0
TLS2_k127_1718267_5 PFAM OsmC family protein K06889,K07397 - - 0.0002688 44.0
TLS2_k127_1719003_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1513.0
TLS2_k127_1719003_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 340.0
TLS2_k127_1719003_2 Ferredoxin - - - 0.000000000000000000000000000000003075 132.0
TLS2_k127_1721172_0 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000006064 201.0
TLS2_k127_172681_0 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 372.0
TLS2_k127_172681_1 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 310.0
TLS2_k127_172681_2 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000005176 236.0
TLS2_k127_172681_3 MgtC family K07507 - - 0.0000000000000000000000000000000000000003898 154.0
TLS2_k127_1728708_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 528.0
TLS2_k127_1728708_1 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006319 251.0
TLS2_k127_1728708_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000003248 128.0
TLS2_k127_1728708_3 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000001798 100.0
TLS2_k127_1728708_4 PFAM Prenyltransferase squalene oxidase - - - 0.0000002968 53.0
TLS2_k127_1731143_0 COG4772 Outer membrane receptor for Fe3 -dicitrate K16091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 613.0
TLS2_k127_1731143_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003552 270.0
TLS2_k127_1731143_2 Belongs to the peptidase S8 family - - - 0.000003735 52.0
TLS2_k127_1731825_0 WD40 domain protein beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000453 290.0
TLS2_k127_1731825_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000004426 103.0
TLS2_k127_1731825_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000008382 76.0
TLS2_k127_1742273_0 Peptidase S9, prolyl oligopeptidase, catalytic domain K01354 - 3.4.21.83 5.31e-250 786.0
TLS2_k127_1742273_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 6.928e-209 655.0
TLS2_k127_1742273_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 422.0
TLS2_k127_1742273_3 excinuclease ABC activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 375.0
TLS2_k127_1742273_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 297.0
TLS2_k127_1742273_5 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 301.0
TLS2_k127_1742273_6 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000006955 196.0
TLS2_k127_1753531_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 4.482e-287 899.0
TLS2_k127_1753531_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 414.0
TLS2_k127_1753531_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000008062 256.0
TLS2_k127_1753531_3 cdp-diacylglycerol pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000006456 183.0
TLS2_k127_1753531_4 - - - - 0.00000000000000000000001942 107.0
TLS2_k127_1755738_0 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 508.0
TLS2_k127_1755738_1 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000112 163.0
TLS2_k127_1755738_2 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000001002 124.0
TLS2_k127_176300_0 Carboxypeptidase regulatory-like domain - - - 2.469e-229 731.0
TLS2_k127_1772149_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000775 210.0
TLS2_k127_1772149_1 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000000000000000000381 146.0
TLS2_k127_1772149_2 lipase activity - - - 0.0002075 48.0
TLS2_k127_1779776_0 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K00058,K16843 - 1.1.1.26,1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000002518 209.0
TLS2_k127_1779776_1 ABC transporter K06147 - - 0.000000000000000000000000000001422 123.0
TLS2_k127_1779776_2 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000003745 98.0
TLS2_k127_1779776_3 NeuB family K01654,K15898 - 2.5.1.56,2.5.1.97 0.0000000000000000001982 98.0
TLS2_k127_1779776_4 Cytidylyltransferase K00983 - 2.7.7.43 0.00000000000000001527 91.0
TLS2_k127_1779776_5 O-methyltransferase activity - - - 0.00000000002355 73.0
TLS2_k127_1780452_0 Carboxypeptidase regulatory-like domain - - - 3.614e-297 949.0
TLS2_k127_1780452_1 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 558.0
TLS2_k127_1780452_2 TrkA-C domain K03316,K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 515.0
TLS2_k127_1780452_3 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 430.0
TLS2_k127_1780452_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000005631 196.0
TLS2_k127_1780452_5 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000003861 105.0
TLS2_k127_1782971_0 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 526.0
TLS2_k127_1782971_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 320.0
TLS2_k127_1782971_2 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 302.0
TLS2_k127_1782971_3 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000009624 181.0
TLS2_k127_1782971_4 methyltransferase - - - 0.000000000000000000000000000000000000003018 152.0
TLS2_k127_1782971_5 - - - - 0.0000000000000003087 82.0
TLS2_k127_1808719_0 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 323.0
TLS2_k127_1808719_1 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000003826 239.0
TLS2_k127_1808719_2 Protein of unknown function (DUF3455) - - - 0.0000000000000000000002163 104.0
TLS2_k127_1811139_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 514.0
TLS2_k127_1811139_1 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 384.0
TLS2_k127_1811139_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005539 279.0
TLS2_k127_1811139_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001467 256.0
TLS2_k127_1811139_4 AntiSigma factor - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.00000000000000000289 94.0
TLS2_k127_1811139_5 Protein of unknown function (DUF433) - - - 0.00000001996 57.0
TLS2_k127_1811139_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000002301 61.0
TLS2_k127_1815710_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 465.0
TLS2_k127_1815710_1 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000001052 173.0
TLS2_k127_1815710_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000005578 144.0
TLS2_k127_1815710_3 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000000114 125.0
TLS2_k127_1821273_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 597.0
TLS2_k127_1821273_1 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 370.0
TLS2_k127_182940_0 Tn3 transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 574.0
TLS2_k127_182940_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000005069 175.0
TLS2_k127_182940_2 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 0.0000001514 56.0
TLS2_k127_182940_3 TIR domain - - - 0.00005441 46.0
TLS2_k127_1843559_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 492.0
TLS2_k127_1843559_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 382.0
TLS2_k127_1843559_2 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000000245 194.0
TLS2_k127_1845069_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000001643 227.0
TLS2_k127_1845069_1 iron assimilation - - - 0.0000000000000000000000000000000000000000000000000000001305 209.0
TLS2_k127_1845069_2 ECF sigma factor - - - 0.000000000000000000000000000000000000000002863 166.0
TLS2_k127_1845508_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 4.388e-196 614.0
TLS2_k127_1845508_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000002331 262.0
TLS2_k127_1845508_2 amine dehydrogenase activity K01053,K13735 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000001098 238.0
TLS2_k127_1845508_3 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000001497 131.0
TLS2_k127_185182_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 489.0
TLS2_k127_185182_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 466.0
TLS2_k127_185182_2 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 398.0
TLS2_k127_185182_3 Inosine-uridine preferring nucleoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 316.0
TLS2_k127_185182_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000005661 242.0
TLS2_k127_185182_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000002607 234.0
TLS2_k127_185182_6 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000808 147.0
TLS2_k127_185182_7 Amidohydrolase family - - - 0.0000000000000000000000000001443 120.0
TLS2_k127_185182_8 Amidohydrolase family - - - 0.0000000008608 67.0
TLS2_k127_1858426_0 arylsulfatase activity - - - 3.422e-210 662.0
TLS2_k127_1858426_1 COG COG1073 Hydrolases of the alpha beta superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 468.0
TLS2_k127_1858426_10 - - - - 0.00001538 55.0
TLS2_k127_1858426_2 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 443.0
TLS2_k127_1858426_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 417.0
TLS2_k127_1858426_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 396.0
TLS2_k127_1858426_5 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 377.0
TLS2_k127_1858426_6 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 306.0
TLS2_k127_1858426_7 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000001771 180.0
TLS2_k127_1858426_8 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000009376 116.0
TLS2_k127_1866979_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 529.0
TLS2_k127_1866979_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 391.0
TLS2_k127_1866979_2 cell adhesion involved in biofilm formation - - - 0.0000000000000000808 94.0
TLS2_k127_1882977_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 319.0
TLS2_k127_1882977_1 TfuA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001414 235.0
TLS2_k127_1882977_2 Integrase core domain - - - 0.000000000000000000000000000000001118 135.0
TLS2_k127_1882977_3 transcriptional - - - 0.00000000000002997 81.0
TLS2_k127_1882977_4 - - - - 0.0001739 50.0
TLS2_k127_1884983_0 PFAM Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 541.0
TLS2_k127_1884983_1 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
TLS2_k127_1884983_2 amidohydrolase - - - 0.00000000000000000000002922 100.0
TLS2_k127_1890064_0 DNA helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 362.0
TLS2_k127_1890064_1 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000341 269.0
TLS2_k127_1890064_2 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000001431 238.0
TLS2_k127_1890064_3 - - - - 0.0000000000000000000000002077 111.0
TLS2_k127_1890064_4 Helix-turn-helix domain - - - 0.000000000000000000004961 98.0
TLS2_k127_1893647_0 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001107 267.0
TLS2_k127_1893647_1 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000003559 108.0
TLS2_k127_1893647_2 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000004595 100.0
TLS2_k127_1893647_3 Domain of unknown function (DUF4926) - - - 0.0004311 48.0
TLS2_k127_1894993_0 PFAM TonB-dependent Receptor - - - 8.457e-245 780.0
TLS2_k127_1894993_1 ATP:ADP antiporter activity K03301 - - 4.569e-237 764.0
TLS2_k127_1894993_2 Sigma-54 interaction domain K15836 - - 4.991e-195 627.0
TLS2_k127_1894993_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 437.0
TLS2_k127_1894993_4 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 396.0
TLS2_k127_1894993_5 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 380.0
TLS2_k127_1894993_6 DREV methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 339.0
TLS2_k127_1894993_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 332.0
TLS2_k127_1894993_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 325.0
TLS2_k127_1894993_9 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000009914 186.0
TLS2_k127_1895905_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 416.0
TLS2_k127_1895905_1 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 384.0
TLS2_k127_1895905_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000004047 151.0
TLS2_k127_1895905_3 beta-propeller repeat - - - 0.000000000000000000000000000000004621 135.0
TLS2_k127_1895905_4 - - - - 0.0000000002167 72.0
TLS2_k127_1895905_5 nuclease activity K07062 - - 0.000000477 56.0
TLS2_k127_1905859_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 361.0
TLS2_k127_1905859_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000003221 267.0
TLS2_k127_1905859_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000001522 179.0
TLS2_k127_1905859_3 - - - - 0.000000000000000000003074 100.0
TLS2_k127_190642_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 614.0
TLS2_k127_190642_1 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 442.0
TLS2_k127_190642_2 PFAM Resolvase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001953 234.0
TLS2_k127_190642_3 IS66 Orf2 like protein K07484 - - 0.0000000000000000000000000000000000000000000001837 171.0
TLS2_k127_190642_4 - - - - 0.000000000000000000000000003716 127.0
TLS2_k127_190642_5 - - - - 0.00000000000000953 79.0
TLS2_k127_1909054_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 564.0
TLS2_k127_1909054_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006953 253.0
TLS2_k127_1909054_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000006889 171.0
TLS2_k127_1917221_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 432.0
TLS2_k127_1917221_1 WD40 domain protein beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 418.0
TLS2_k127_1917221_2 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000004727 201.0
TLS2_k127_1917221_3 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000002808 158.0
TLS2_k127_1917221_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000522 99.0
TLS2_k127_1917221_5 Putative zinc-finger - - - 0.00000000000000281 87.0
TLS2_k127_1917221_6 PFAM TPR repeat-containing protein - - - 0.0000000002094 72.0
TLS2_k127_1919981_0 TonB-dependent receptor - - - 1.233e-196 653.0
TLS2_k127_1919981_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 336.0
TLS2_k127_1919981_2 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 319.0
TLS2_k127_1919981_3 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 305.0
TLS2_k127_1919981_4 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001831 280.0
TLS2_k127_1919981_5 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000000003587 207.0
TLS2_k127_1919981_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000001713 193.0
TLS2_k127_1919981_7 alpha beta - - - 0.000000000000000000000000000000000000000005203 171.0
TLS2_k127_1928661_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 519.0
TLS2_k127_1928661_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 515.0
TLS2_k127_1928661_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 481.0
TLS2_k127_1928661_3 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 469.0
TLS2_k127_1928661_4 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 378.0
TLS2_k127_1928661_5 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 393.0
TLS2_k127_1928661_6 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 350.0
TLS2_k127_1928661_7 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000004962 173.0
TLS2_k127_1937076_0 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 437.0
TLS2_k127_1937076_1 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000007342 234.0
TLS2_k127_1938287_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 2.849e-281 881.0
TLS2_k127_1938287_1 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 456.0
TLS2_k127_1938287_2 Major facilitator superfamily K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 373.0
TLS2_k127_1938287_3 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000007362 196.0
TLS2_k127_1938287_4 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000003148 172.0
TLS2_k127_1938287_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000009926 126.0
TLS2_k127_1942072_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 567.0
TLS2_k127_1942072_1 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 333.0
TLS2_k127_1942072_2 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000002727 224.0
TLS2_k127_1942072_3 anaphase-promoting complex-dependent catabolic process - - - 0.000000000000000000000000000000000000003018 152.0
TLS2_k127_1942329_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 496.0
TLS2_k127_1942329_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 353.0
TLS2_k127_1942329_2 Maltose acetyltransferase K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000002891 232.0
TLS2_k127_1942329_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00003723 46.0
TLS2_k127_195874_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000002332 166.0
TLS2_k127_1962825_0 PFAM Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 328.0
TLS2_k127_1962825_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 289.0
TLS2_k127_1962825_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003289 241.0
TLS2_k127_1962825_3 Glucose inhibited division protein A - - - 0.000000000000000000000000000000000000000000000008329 176.0
TLS2_k127_1962825_4 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000000000000000000000000006104 121.0
TLS2_k127_1964293_0 Cytochrome c - - - 0.0 1141.0
TLS2_k127_1964293_1 Protein of unknown function (DUF1501) - - - 7.045e-226 707.0
TLS2_k127_1964293_10 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00006612 46.0
TLS2_k127_1964293_2 carboxylic acid catabolic process K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 570.0
TLS2_k127_1964293_3 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 559.0
TLS2_k127_1964293_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000002019 233.0
TLS2_k127_1964293_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000002511 134.0
TLS2_k127_1964293_6 Tetratricopeptide repeat - - - 0.00000000000000000000008403 108.0
TLS2_k127_1964293_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000004597 113.0
TLS2_k127_1964293_8 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000006054 61.0
TLS2_k127_1964293_9 Glutathione peroxidase - - - 0.000004617 50.0
TLS2_k127_1966073_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 1.637e-317 1002.0
TLS2_k127_1966073_1 extracellular polysaccharide biosynthetic process K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 481.0
TLS2_k127_1966073_2 AAA domain K08252 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 356.0
TLS2_k127_1966073_3 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000003082 251.0
TLS2_k127_1966073_4 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000001746 194.0
TLS2_k127_1966073_5 Domain of unknown function (DUF2382) - - - 0.0000000000000008871 89.0
TLS2_k127_1968304_0 eRF1 domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 388.0
TLS2_k127_1978288_0 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 507.0
TLS2_k127_1978288_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004986 261.0
TLS2_k127_1978939_0 PFAM SMP-30 Gluconolaconase - - - 3.892e-230 733.0
TLS2_k127_1978939_1 SpoIVB peptidase S55 - - - 1.816e-220 701.0
TLS2_k127_1978939_10 Universal stress protein - - - 0.00000000000000000000000000000000001584 145.0
TLS2_k127_1978939_11 YCII-related domain - - - 0.000000000000000000001174 100.0
TLS2_k127_1978939_12 - - - - 0.000000000000000000003302 93.0
TLS2_k127_1978939_13 - - - - 0.000000000000000000004889 98.0
TLS2_k127_1978939_14 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000001811 75.0
TLS2_k127_1978939_15 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000001718 77.0
TLS2_k127_1978939_2 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 590.0
TLS2_k127_1978939_3 Hypothetical glycosyl hydrolase 6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 579.0
TLS2_k127_1978939_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 557.0
TLS2_k127_1978939_5 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 332.0
TLS2_k127_1978939_6 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000003763 236.0
TLS2_k127_1978939_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000005732 213.0
TLS2_k127_1978939_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000003179 192.0
TLS2_k127_1999035_0 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 504.0
TLS2_k127_1999035_1 membrane organization K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 334.0
TLS2_k127_1999035_2 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002322 254.0
TLS2_k127_1999035_3 Putative esterase - - - 0.00000000000000000000000000000000000000000523 170.0
TLS2_k127_1999035_4 arylsulfatase A - - - 0.00000000000000000000000000000000000000001791 157.0
TLS2_k127_2003285_0 cobalamin binding K01847,K01849 - 5.4.99.2 1.087e-305 953.0
TLS2_k127_2003285_1 CoA carboxylase activity K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 3.865e-267 839.0
TLS2_k127_2003285_2 Methylmalonyl-CoA mutase K01847,K03763,K14447 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016999,GO:0017144,GO:0019541,GO:0019678,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046459,GO:0071704,GO:0071944 2.7.7.7,5.4.99.2,5.4.99.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 531.0
TLS2_k127_2003285_3 Conserved carboxylase domain K03416 - 2.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 331.0
TLS2_k127_2003285_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001308 264.0
TLS2_k127_2003285_5 Biotin-requiring enzyme K17490 - 2.1.3.1 0.00000000000000000000000000000000000008012 145.0
TLS2_k127_2005121_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 300.0
TLS2_k127_2005121_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000002178 211.0
TLS2_k127_2005391_0 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006195 288.0
TLS2_k127_2005391_1 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009957 246.0
TLS2_k127_2005391_2 Integrase - - - 0.00000000000000000000002374 104.0
TLS2_k127_2005391_3 overlaps another CDS with the same product name - - - 0.000000000000162 73.0
TLS2_k127_2006157_0 Belongs to the peptidase S41A family - - - 0.000000000000000000000000000000000000000006102 173.0
TLS2_k127_2006157_1 - - - - 0.000000000000000000000001609 120.0
TLS2_k127_2008675_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 385.0
TLS2_k127_2008675_1 response regulator, receiver - - - 0.00000000000000000000000000000000001996 141.0
TLS2_k127_2008675_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000002089 138.0
TLS2_k127_2008675_3 BON domain - - - 0.0000000000000000000000000003684 117.0
TLS2_k127_2017021_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003159 260.0
TLS2_k127_2017021_1 Protein of unknown function DUF45 K07043 - - 0.000000000000006255 80.0
TLS2_k127_2017021_2 - - - - 0.0000000000003682 75.0
TLS2_k127_2017021_3 Protein of unknown function DUF45 K07043 - - 0.00000001411 56.0
TLS2_k127_2017021_4 Transposase zinc-binding domain - - - 0.0003888 47.0
TLS2_k127_2022043_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 351.0
TLS2_k127_2022043_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 345.0
TLS2_k127_2022043_2 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000008284 183.0
TLS2_k127_2022043_3 Glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000003169 171.0
TLS2_k127_2022043_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000701 146.0
TLS2_k127_2022043_5 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000005066 125.0
TLS2_k127_2022043_6 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.00000000000000000000002266 101.0
TLS2_k127_2022043_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0007316 52.0
TLS2_k127_202252_0 Glycosyl hydrolases family 43 - - - 1.255e-293 914.0
TLS2_k127_202252_1 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 417.0
TLS2_k127_202252_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001049 263.0
TLS2_k127_2024943_0 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 307.0
TLS2_k127_2024943_1 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000003227 181.0
TLS2_k127_2024943_2 histidine kinase A domain protein - - - 0.00000000000000000000000003979 117.0
TLS2_k127_2024943_3 iron dependent repressor - - - 0.00000000000234 69.0
TLS2_k127_2024943_4 Bli-3 protein - - - 0.0000003456 54.0
TLS2_k127_2024943_5 general stress protein 26 - - - 0.00085 45.0
TLS2_k127_2030160_0 PFAM delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 496.0
TLS2_k127_2030160_1 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 511.0
TLS2_k127_2030160_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 376.0
TLS2_k127_2030160_3 Lysin motif - - - 0.0000000000000000000000000000000000000008086 158.0
TLS2_k127_2030160_4 - - - - 0.000000000000000000000000000000000000002698 154.0
TLS2_k127_2030160_5 Pfam:KaiC K08482 - - 0.00000000000000000000000000000514 135.0
TLS2_k127_20557_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 444.0
TLS2_k127_20557_1 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 439.0
TLS2_k127_20557_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000008749 221.0
TLS2_k127_205742_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 503.0
TLS2_k127_205742_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004985 276.0
TLS2_k127_205742_2 Carbohydrate family 9 binding domain-like - - - 0.00000000000000006762 93.0
TLS2_k127_2064168_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 361.0
TLS2_k127_2064168_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000008559 74.0
TLS2_k127_2066841_0 Belongs to the 'phage' integrase family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007917 246.0
TLS2_k127_2066841_1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000009315 203.0
TLS2_k127_2066841_2 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000004036 181.0
TLS2_k127_2066841_3 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000001125 167.0
TLS2_k127_2067692_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 432.0
TLS2_k127_2067692_1 Prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 357.0
TLS2_k127_2067692_2 Phosphotransferase enzyme family - - - 0.000004589 57.0
TLS2_k127_2068754_0 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 553.0
TLS2_k127_2068754_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008384 254.0
TLS2_k127_2068754_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000004865 216.0
TLS2_k127_2068754_3 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000001133 209.0
TLS2_k127_2070781_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 559.0
TLS2_k127_2070781_1 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000009013 91.0
TLS2_k127_2072096_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 569.0
TLS2_k127_2072096_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 303.0
TLS2_k127_2072326_0 Belongs to the 'phage' integrase family K07484 - - 0.00000000000000000000000000000000002051 137.0
TLS2_k127_2072326_1 Transposase IS66 family - - - 0.00000000000000000000001061 103.0
TLS2_k127_2072326_2 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000000006699 97.0
TLS2_k127_2072326_3 cheY-homologous receiver domain - - - 0.0000000000002637 77.0
TLS2_k127_2072326_4 Transposase K07484 - - 0.00005622 48.0
TLS2_k127_2074498_0 ABC transporter K06158 - - 2.52e-288 897.0
TLS2_k127_2074498_1 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 556.0
TLS2_k127_2074498_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 382.0
TLS2_k127_207839_0 Alcohol dehydrogenase zinc-binding domain protein K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 370.0
TLS2_k127_207839_1 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 310.0
TLS2_k127_2080124_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1381.0
TLS2_k127_2080124_1 Prolyl oligopeptidase family - - - 1.203e-250 782.0
TLS2_k127_2080124_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000001327 153.0
TLS2_k127_2080124_12 - - - - 0.0000000000000000000000000000000000000675 149.0
TLS2_k127_2080124_13 cAMP biosynthetic process - - - 0.0000000000000000002621 100.0
TLS2_k127_2080124_14 Tetratricopeptide repeat - - - 0.0004386 52.0
TLS2_k127_2080124_2 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 553.0
TLS2_k127_2080124_3 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 487.0
TLS2_k127_2080124_4 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 466.0
TLS2_k127_2080124_5 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 337.0
TLS2_k127_2080124_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 318.0
TLS2_k127_2080124_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 315.0
TLS2_k127_2080124_8 response to abiotic stimulus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 288.0
TLS2_k127_2080124_9 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009937 262.0
TLS2_k127_2080206_0 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 412.0
TLS2_k127_2080206_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 374.0
TLS2_k127_2080206_2 - - - - 0.000000000000002931 79.0
TLS2_k127_2080206_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000859 74.0
TLS2_k127_2081431_0 Hypothetical glycosyl hydrolase 6 - - - 6.911e-245 775.0
TLS2_k127_2087292_0 Aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 522.0
TLS2_k127_2087292_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000007718 164.0
TLS2_k127_2091418_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 297.0
TLS2_k127_2091418_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
TLS2_k127_2091418_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001626 254.0
TLS2_k127_2091418_3 With GsiBCD is involved in glutathione import K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000001097 230.0
TLS2_k127_2091418_4 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.000000000000000000000000000000000000000000000000000000000000002336 230.0
TLS2_k127_2091418_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000009995 174.0
TLS2_k127_2093929_0 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 410.0
TLS2_k127_2093929_1 Alpha-amylase domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 362.0
TLS2_k127_2093929_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000316 246.0
TLS2_k127_2093929_3 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.00000000000000000000000000000000000000000000000000000007268 210.0
TLS2_k127_2095109_0 Carboxypeptidase regulatory-like domain - - - 3.899e-245 773.0
TLS2_k127_2095109_1 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 597.0
TLS2_k127_2095109_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000006717 253.0
TLS2_k127_2095109_3 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000003529 51.0
TLS2_k127_2095653_0 PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 486.0
TLS2_k127_2095653_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447 282.0
TLS2_k127_2096270_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 409.0
TLS2_k127_2096270_1 Major Facilitator Superfamily K03535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 398.0
TLS2_k127_2096270_10 WD40 domain protein beta Propeller - - - 0.000000000594 66.0
TLS2_k127_2096270_11 - - - - 0.000001454 59.0
TLS2_k127_2096270_2 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 308.0
TLS2_k127_2096270_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000003422 175.0
TLS2_k127_2096270_4 TIGRFAM addiction module toxin, Txe YoeB family K19158 - - 0.000000000000000000000000000000000000001247 148.0
TLS2_k127_2096270_5 Cupin domain - - - 0.0000000000000000000000000000000000002368 156.0
TLS2_k127_2096270_6 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000003225 149.0
TLS2_k127_2096270_7 toxin-antitoxin pair type II binding K08591,K19159 - 2.3.1.15 0.00000000000000000000000000000000006459 135.0
TLS2_k127_2096270_8 RNA recognition motif - - - 0.00000000000000000000000000000000007638 136.0
TLS2_k127_2096270_9 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000001874 133.0
TLS2_k127_2096273_0 Beta galactosidase small chain K01190 - 3.2.1.23 0.0 1272.0
TLS2_k127_2096273_1 PFAM Organic solvent tolerance protein K04744 - - 2.15e-238 762.0
TLS2_k127_2096273_2 Beta-lactamase - - - 1.008e-210 674.0
TLS2_k127_2096273_3 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 360.0
TLS2_k127_2096676_0 PFAM Sulfatase - - - 2.571e-228 719.0
TLS2_k127_2096676_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 382.0
TLS2_k127_2096676_2 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 357.0
TLS2_k127_2096676_3 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 352.0
TLS2_k127_209671_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000009768 174.0
TLS2_k127_209671_1 PFAM glycosyl transferase family 28 K05841 - 2.4.1.173 0.000000000000000000000000000000000000002107 154.0
TLS2_k127_209671_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.12 0.0000000000004216 79.0
TLS2_k127_2100151_0 peptidyl-tyrosine sulfation - - - 1.343e-312 977.0
TLS2_k127_2100151_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 2.062e-288 906.0
TLS2_k127_2100151_2 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 483.0
TLS2_k127_2100151_3 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000243 111.0
TLS2_k127_2100151_4 DNA protecting protein DprA K04096 - - 0.000000000001224 68.0
TLS2_k127_2103016_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 506.0
TLS2_k127_2103016_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 290.0
TLS2_k127_2103016_3 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001155 240.0
TLS2_k127_2103016_4 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000003444 113.0
TLS2_k127_2103016_5 Transglycosylase associated protein - - - 0.00000000000000000000001799 103.0
TLS2_k127_2104179_0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 405.0
TLS2_k127_2104179_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000006869 243.0
TLS2_k127_2104179_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000002513 243.0
TLS2_k127_2104179_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000001432 116.0
TLS2_k127_2104179_4 peptidase S1 and S6 chymotrypsin Hap - - - 0.00000000000000000000008142 102.0
TLS2_k127_2106581_0 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 416.0
TLS2_k127_2106581_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 357.0
TLS2_k127_2106581_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 306.0
TLS2_k127_2106581_3 glycosyl transferase family 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005025 275.0
TLS2_k127_2106581_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000933 203.0
TLS2_k127_2106581_5 O-methyltransferase activity - - - 0.000000000000000000000000000000000000004273 156.0
TLS2_k127_2106581_6 Protein of unknown function (DUF563) - - - 0.0000000000000000000000000000000001119 149.0
TLS2_k127_2107687_0 lipopolysaccharide transport K22110 - - 0.0 1341.0
TLS2_k127_2107687_1 Carboxyl transferase domain - - - 6.874e-252 785.0
TLS2_k127_2107687_2 Glycogen debranching enzyme - - - 4.132e-239 755.0
TLS2_k127_2107687_3 COG3119 Arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 484.0
TLS2_k127_2107687_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 473.0
TLS2_k127_2107687_5 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 333.0
TLS2_k127_2107687_6 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000005693 196.0
TLS2_k127_2107687_7 AI-2E family transporter - - - 0.0000000135 62.0
TLS2_k127_2108712_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 330.0
TLS2_k127_2108712_1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002864 293.0
TLS2_k127_2109129_0 efflux transmembrane transporter activity - - - 1.205e-252 805.0
TLS2_k127_2109129_1 Pfam:DUF303 K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 490.0
TLS2_k127_2109129_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 414.0
TLS2_k127_2109129_3 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 409.0
TLS2_k127_2109129_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000004688 263.0
TLS2_k127_2109129_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008301 248.0
TLS2_k127_2109129_6 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000004996 204.0
TLS2_k127_2109129_7 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.000000000000000000000000000000003358 129.0
TLS2_k127_2113572_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 319.0
TLS2_k127_2113572_1 - - - - 0.000000000000000000000000000000000001833 152.0
TLS2_k127_2113572_2 - - - - 0.00000000000000000000001042 104.0
TLS2_k127_2113572_3 nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000004829 112.0
TLS2_k127_2113572_4 Protein of unknown function (DUF433) - - - 0.000000000000000000003022 94.0
TLS2_k127_2113572_5 - - - - 0.00000005442 63.0
TLS2_k127_2114213_0 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 447.0
TLS2_k127_2114213_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K17217 - 2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 443.0
TLS2_k127_2120270_0 L-lactate permease K03303 - - 2.823e-212 672.0
TLS2_k127_2120270_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 532.0
TLS2_k127_2120270_2 Chase2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 384.0
TLS2_k127_2120270_3 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 371.0
TLS2_k127_2120270_4 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 308.0
TLS2_k127_2122819_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1198.0
TLS2_k127_2122819_1 WD40-like Beta Propeller - - - 0.0000000000000000002644 95.0
TLS2_k127_2125195_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 3.396e-297 922.0
TLS2_k127_2125195_1 Transcriptional regulatory protein, C terminal K02483,K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000393 243.0
TLS2_k127_2125195_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000003055 141.0
TLS2_k127_2125195_3 hyperosmotic response - - - 0.00000000000000000000000002051 123.0
TLS2_k127_2125524_0 Heat shock 70 kDa protein K04043 - - 3.398e-240 764.0
TLS2_k127_2125524_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 2.359e-204 645.0
TLS2_k127_2125524_10 heat shock protein binding - - - 0.0000000000000000000000000001097 121.0
TLS2_k127_2125524_11 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000001305 125.0
TLS2_k127_2125524_12 glycosyl transferase family - - - 0.0000000000000000000002028 112.0
TLS2_k127_2125524_14 PepSY-associated TM region - - - 0.00000000000004272 80.0
TLS2_k127_2125524_15 Replication initiator protein - - - 0.0000000001311 74.0
TLS2_k127_2125524_16 transcriptional regulator, MerR family - - - 0.00003134 48.0
TLS2_k127_2125524_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 434.0
TLS2_k127_2125524_4 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 383.0
TLS2_k127_2125524_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001461 237.0
TLS2_k127_2125524_6 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002625 232.0
TLS2_k127_2125524_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000002339 189.0
TLS2_k127_2125524_8 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000007526 153.0
TLS2_k127_2125524_9 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000003305 133.0
TLS2_k127_2127226_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 7.821e-245 766.0
TLS2_k127_2127226_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.458e-219 687.0
TLS2_k127_2127226_2 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 398.0
TLS2_k127_2127226_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005894 262.0
TLS2_k127_2127226_4 Catalase K07217 - - 0.000000000000000000000000000000000000000000000006489 174.0
TLS2_k127_2135723_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002111 261.0
TLS2_k127_2135723_1 TfuA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000009685 213.0
TLS2_k127_2135723_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000002096 118.0
TLS2_k127_2140605_0 FAD linked oxidase domain protein - - - 2.887e-278 886.0
TLS2_k127_2140605_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 354.0
TLS2_k127_2140605_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000003019 234.0
TLS2_k127_2141480_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1340.0
TLS2_k127_2141480_1 Peptidase family M1 domain - - - 3.097e-234 747.0
TLS2_k127_2141480_2 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 376.0
TLS2_k127_2141480_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001629 283.0
TLS2_k127_2141480_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000003726 112.0
TLS2_k127_2141480_5 Metal-dependent hydrolase - - - 0.00001963 47.0
TLS2_k127_2145797_0 Carbon-nitrogen hydrolase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 299.0
TLS2_k127_2145797_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000006937 173.0
TLS2_k127_2145797_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000003965 156.0
TLS2_k127_2151138_0 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 394.0
TLS2_k127_2151138_1 PFAM transposase, mutator type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 362.0
TLS2_k127_2151138_2 Berberine and berberine like - - - 0.00000000000000000000000000000000131 133.0
TLS2_k127_2151138_3 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000004231 120.0
TLS2_k127_2151138_4 FAD linked oxidase - - - 0.0000000005207 62.0
TLS2_k127_2160072_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 482.0
TLS2_k127_2160072_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.00000000000000000002005 91.0
TLS2_k127_2163317_0 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 375.0
TLS2_k127_2163317_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 303.0
TLS2_k127_2163317_2 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003233 246.0
TLS2_k127_2163317_3 - - - - 0.000000000000676 72.0
TLS2_k127_2163317_4 - - - - 0.00000002067 60.0
TLS2_k127_2179986_0 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000001187 230.0
TLS2_k127_2179986_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000001409 182.0
TLS2_k127_2179986_2 manually curated - - - 0.000000000000000000000000000000000000000002089 160.0
TLS2_k127_2179986_3 PFAM Integrase catalytic K07497 - - 0.00000000000000000000000000000000004279 142.0
TLS2_k127_2179986_4 transposase activity K07483,K07497 - - 0.0000000000000009748 81.0
TLS2_k127_2184703_0 Phage tail sheath protein K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 610.0
TLS2_k127_2184703_1 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 620.0
TLS2_k127_2184703_2 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 379.0
TLS2_k127_2184703_3 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 323.0
TLS2_k127_2184703_4 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 320.0
TLS2_k127_2184703_5 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 329.0
TLS2_k127_2184703_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003415 249.0
TLS2_k127_2184703_7 - - - - 0.00000000000000000000000000000000000000000000003909 178.0
TLS2_k127_2184703_8 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000003228 154.0
TLS2_k127_2184703_9 Transcriptional regulator antitoxin, MazE K07172 - - 0.00000000000000001329 87.0
TLS2_k127_2191984_0 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 516.0
TLS2_k127_2191984_1 Uncharacterized protein conserved in bacteria (DUF2264) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 476.0
TLS2_k127_2191984_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 412.0
TLS2_k127_2191984_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000005213 226.0
TLS2_k127_2191984_4 Peptidase family M23 - - - 0.000000000000000000006285 93.0
TLS2_k127_2191984_5 COGs COG1148 Heterodisulfide reductase subunit A and related polyferredoxins - - - 0.000000000000004513 81.0
TLS2_k127_2191984_6 mandelate racemase muconate lactonizing K01631,K01684,K08323 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575 4.1.2.21,4.2.1.6,4.2.1.8 0.0000001454 56.0
TLS2_k127_219851_0 PFAM Glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 457.0
TLS2_k127_219851_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 394.0
TLS2_k127_219851_2 Glycosyl transferases group 1 K16148 - 2.4.1.342 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 374.0
TLS2_k127_219851_3 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 323.0
TLS2_k127_219851_4 ECF sigma factor - - - 0.000000000000000000000000000225 119.0
TLS2_k127_219851_5 ECF sigma factor - - - 0.00000000002473 69.0
TLS2_k127_2199688_0 Domain of unknown function (DUF5117) - - - 3.492e-271 854.0
TLS2_k127_2199688_1 COG3119 Arylsulfatase A K01138 - - 1.772e-224 711.0
TLS2_k127_2199688_2 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 1.013e-201 646.0
TLS2_k127_2199688_3 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 449.0
TLS2_k127_2199688_4 Transposase domain (DUF772) K07487 - - 0.0000000000000000000000000000000000000000000000000000000000000007184 229.0
TLS2_k127_2199688_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000001813 199.0
TLS2_k127_2199688_6 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000002224 192.0
TLS2_k127_2199688_7 phosphorelay signal transduction system K02477,K07705,K21696 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000005267 147.0
TLS2_k127_2199688_8 DinB superfamily - - - 0.000000000000000000000000000000007901 132.0
TLS2_k127_2199688_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000003953 134.0
TLS2_k127_2202863_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 636.0
TLS2_k127_2202863_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 345.0
TLS2_k127_2202863_2 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 291.0
TLS2_k127_2202863_3 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005905 262.0
TLS2_k127_2202863_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000002416 211.0
TLS2_k127_2202863_5 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.000000000000000000000000000001192 122.0
TLS2_k127_2203665_0 synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 521.0
TLS2_k127_2203665_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 524.0
TLS2_k127_2203665_2 Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 340.0
TLS2_k127_2203665_3 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000002557 178.0
TLS2_k127_2203665_4 Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000003855 151.0
TLS2_k127_2203665_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000001661 143.0
TLS2_k127_2203665_6 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000002483 100.0
TLS2_k127_2204012_0 Carbohydrate phosphorylase K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 3.829e-242 758.0
TLS2_k127_2207047_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 9.676e-226 706.0
TLS2_k127_2207047_2 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000002578 122.0
TLS2_k127_2207047_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000007249 121.0
TLS2_k127_2207047_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000005297 53.0
TLS2_k127_2210171_0 MacB-like periplasmic core domain - - - 2.845e-224 724.0
TLS2_k127_2210171_1 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000003555 146.0
TLS2_k127_2210171_2 Domain of unknown function (DUF4440) - - - 0.000000000000000000005283 98.0
TLS2_k127_2211338_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 524.0
TLS2_k127_2226197_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 435.0
TLS2_k127_2226197_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000001106 151.0
TLS2_k127_2226197_3 Baseplate J-like protein - - - 0.00000000000000000000000005176 116.0
TLS2_k127_223036_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002003 297.0
TLS2_k127_223036_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006818 271.0
TLS2_k127_223036_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000811 166.0
TLS2_k127_2236816_0 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 586.0
TLS2_k127_2236816_1 Glycosyl Hydrolase Family 88 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 349.0
TLS2_k127_2236816_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K05991 - 3.2.1.123 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 289.0
TLS2_k127_2236816_3 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000001326 246.0
TLS2_k127_2236816_4 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.0000000000000000000175 94.0
TLS2_k127_2236816_5 Serine threonine protein kinase K08282 - 2.7.11.1 0.0000754 52.0
TLS2_k127_2237492_0 MacB-like periplasmic core domain - - - 1.772e-312 971.0
TLS2_k127_2237492_1 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000009194 106.0
TLS2_k127_2245285_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
TLS2_k127_2245285_1 PFAM chemotaxis sensory transducer K03406,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006196 275.0
TLS2_k127_2251291_0 response to abiotic stimulus K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 546.0
TLS2_k127_2251291_1 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 509.0
TLS2_k127_2251291_2 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 341.0
TLS2_k127_2251291_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004519 224.0
TLS2_k127_2251291_4 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000003382 166.0
TLS2_k127_2251291_5 - - - - 0.0000000000000000000002321 102.0
TLS2_k127_2257001_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 383.0
TLS2_k127_2257001_1 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008355 243.0
TLS2_k127_2257001_2 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000008631 211.0
TLS2_k127_2257001_3 Sulfatase - - - 0.000000000000000000222 92.0
TLS2_k127_2264790_0 Transposase or inactivated derivative - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 312.0
TLS2_k127_2264790_1 Transcriptional regulator K02483 - - 0.00000000000006465 79.0
TLS2_k127_2264790_2 amine dehydrogenase activity - - - 0.0000001632 63.0
TLS2_k127_2267696_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.109e-205 644.0
TLS2_k127_2267696_1 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 466.0
TLS2_k127_2267696_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 453.0
TLS2_k127_2267696_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 403.0
TLS2_k127_2267696_4 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 310.0
TLS2_k127_2267696_5 Belongs to the frataxin family K06202,K19054 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 1.16.3.1 0.0000000000000000000000000000000004242 134.0
TLS2_k127_2270913_0 Oligopeptide transporter OPT - - - 1.249e-276 865.0
TLS2_k127_2270913_1 AcrB/AcrD/AcrF family K15726 - - 9.739e-196 624.0
TLS2_k127_2270913_2 efflux transmembrane transporter activity K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003163 261.0
TLS2_k127_2270913_3 Beta-lactamase superfamily domain K03476 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005833 248.0
TLS2_k127_2270913_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000001127 242.0
TLS2_k127_2270913_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000008471 162.0
TLS2_k127_2270913_6 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000002857 133.0
TLS2_k127_2270913_7 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.00000000000000000000000006625 113.0
TLS2_k127_2272703_0 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 457.0
TLS2_k127_2272703_1 Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 377.0
TLS2_k127_2272703_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000002993 108.0
TLS2_k127_2272703_3 IS66 Orf2 like protein K07484 - - 0.00000000000000000000513 92.0
TLS2_k127_2277952_0 cell redox homeostasis K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 2.682e-212 668.0
TLS2_k127_2277952_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 340.0
TLS2_k127_2277952_2 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000001759 224.0
TLS2_k127_2277952_3 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000001126 197.0
TLS2_k127_2292073_0 cytochrome C - - - 0.0 1350.0
TLS2_k127_2292073_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 578.0
TLS2_k127_2293724_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 4368.0
TLS2_k127_2293724_1 protein tyrosine kinase activity K08252 - 2.7.10.1 0.00000000003049 67.0
TLS2_k127_2293724_2 CsbD-like - - - 0.00000002173 59.0
TLS2_k127_2293724_3 Transposase K07483 - - 0.00000002452 60.0
TLS2_k127_2293724_4 Belongs to the ompA family K12216 - - 0.00001663 51.0
TLS2_k127_2308757_0 TonB-dependent receptor - - - 8.819e-211 696.0
TLS2_k127_2308757_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 568.0
TLS2_k127_2308757_2 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
TLS2_k127_2308757_3 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000001417 97.0
TLS2_k127_2309693_0 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008369 284.0
TLS2_k127_2309693_1 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.00000000000000000000000007695 109.0
TLS2_k127_2309693_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000008046 107.0
TLS2_k127_2309693_3 - - - - 0.0000000000000427 74.0
TLS2_k127_2313650_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 400.0
TLS2_k127_231473_0 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009234 325.0
TLS2_k127_231473_1 Enoyl-CoA hydratase/isomerase K13767,K13816 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002165 263.0
TLS2_k127_231473_2 isobutyryl-CoA mutase activity K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000003394 227.0
TLS2_k127_2315129_0 ABC transporter K10441,K10545,K10562 - 3.6.3.17 5.827e-207 654.0
TLS2_k127_2315129_1 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 469.0
TLS2_k127_2315129_2 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 452.0
TLS2_k127_2315129_3 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 425.0
TLS2_k127_2315129_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000005046 235.0
TLS2_k127_2315129_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000001891 109.0
TLS2_k127_2315129_6 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0004026 45.0
TLS2_k127_2315129_7 - - - - 0.0009701 50.0
TLS2_k127_2315187_0 Peptidase M1, membrane alanine aminopeptidase - - - 7.074e-271 849.0
TLS2_k127_2315187_1 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 297.0
TLS2_k127_2315187_2 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000006085 139.0
TLS2_k127_2315187_3 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 GO:0003674,GO:0003824,GO:0006091,GO:0006457,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0022900,GO:0044237,GO:0050896,GO:0055114 - 0.000000000000006149 79.0
TLS2_k127_2315187_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000002358 67.0
TLS2_k127_2316005_0 glycoside hydrolase family 2 sugar binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 417.0
TLS2_k127_2316005_1 L-fucose isomerase, C-terminal domain - - - 0.000000000000000000000000000000000000001247 148.0
TLS2_k127_2328628_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 490.0
TLS2_k127_2328628_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 378.0
TLS2_k127_2328628_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000002118 182.0
TLS2_k127_2328628_3 acylphosphatase activity K01512 - 3.6.1.7 0.00000000000000000000000001275 113.0
TLS2_k127_2335697_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004906 268.0
TLS2_k127_2335697_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000002344 240.0
TLS2_k127_2335697_2 PhoQ Sensor - - - 0.00000000000000000000004162 105.0
TLS2_k127_2336790_0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000003764 200.0
TLS2_k127_2336790_1 Flagellar hook-associated protein 2 N-terminus - - - 0.0000000000000000000000001109 122.0
TLS2_k127_2336790_2 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.00000000000002145 76.0
TLS2_k127_2336790_3 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0004035 45.0
TLS2_k127_2338206_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1202.0
TLS2_k127_2338206_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 497.0
TLS2_k127_2338206_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007174 263.0
TLS2_k127_2338206_11 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004104 261.0
TLS2_k127_2338206_12 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000004291 246.0
TLS2_k127_2338206_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000008763 235.0
TLS2_k127_2338206_14 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000007324 228.0
TLS2_k127_2338206_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000002312 230.0
TLS2_k127_2338206_16 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000228 203.0
TLS2_k127_2338206_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000001228 186.0
TLS2_k127_2338206_18 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000000000001343 174.0
TLS2_k127_2338206_19 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000000000606 169.0
TLS2_k127_2338206_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 462.0
TLS2_k127_2338206_20 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000001321 169.0
TLS2_k127_2338206_21 - - - - 0.0000000000000000009147 94.0
TLS2_k127_2338206_22 Hfq protein K03666 - - 0.0000000000000009668 79.0
TLS2_k127_2338206_23 - - - - 0.00000227 58.0
TLS2_k127_2338206_3 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 372.0
TLS2_k127_2338206_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 358.0
TLS2_k127_2338206_5 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 338.0
TLS2_k127_2338206_6 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 341.0
TLS2_k127_2338206_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 314.0
TLS2_k127_2338206_8 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 303.0
TLS2_k127_2338206_9 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001274 287.0
TLS2_k127_234701_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 6.014e-242 754.0
TLS2_k127_2347400_0 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 308.0
TLS2_k127_2347400_1 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008441 240.0
TLS2_k127_2347400_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000002407 240.0
TLS2_k127_2347400_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000001226 216.0
TLS2_k127_2347400_5 desaturase K00507 - 1.14.19.1 0.0000000002613 61.0
TLS2_k127_23542_0 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
TLS2_k127_23542_1 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000002052 225.0
TLS2_k127_23542_2 Putative cyclase - - - 0.0000000000000002777 80.0
TLS2_k127_2364578_0 - - - - 0.0 1302.0
TLS2_k127_2364578_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 508.0
TLS2_k127_2364578_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 305.0
TLS2_k127_2364578_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000005571 191.0
TLS2_k127_2377079_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 555.0
TLS2_k127_2377079_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 400.0
TLS2_k127_2377079_10 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000003016 170.0
TLS2_k127_2377079_11 - - - - 0.0000000000000000000000000000000000000000009126 167.0
TLS2_k127_2377079_12 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000001694 165.0
TLS2_k127_2377079_13 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000003238 147.0
TLS2_k127_2377079_16 - - - - 0.00001206 47.0
TLS2_k127_2377079_2 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 385.0
TLS2_k127_2377079_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 350.0
TLS2_k127_2377079_4 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 322.0
TLS2_k127_2377079_5 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 322.0
TLS2_k127_2377079_6 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004268 273.0
TLS2_k127_2377079_7 von Willebrand factor, type A K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000435 252.0
TLS2_k127_2377079_8 dUTPase K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000002553 237.0
TLS2_k127_2377079_9 Cytochrome c oxidase subunit III - - - 0.0000000000000000000000000000000000000000000000000000003078 199.0
TLS2_k127_2395732_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 366.0
TLS2_k127_2395732_1 phosphorelay signal transduction system - - - 0.00000000000000000000000003271 113.0
TLS2_k127_2395757_0 choline dehydrogenase activity K03333 - 1.1.3.6 0.0 1344.0
TLS2_k127_2395757_1 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 287.0
TLS2_k127_2395757_2 phage integrase domain protein SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 291.0
TLS2_k127_2395757_3 COG3119 Arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000003539 194.0
TLS2_k127_2395757_4 Putative transposase - - - 0.0000000000000000000000000000000000000000001666 168.0
TLS2_k127_2395757_5 Protein of unknown function (DUF433) - - - 0.0000000000000000000000001099 108.0
TLS2_k127_2395757_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000004536 63.0
TLS2_k127_2395757_7 - - - - 0.000000001543 62.0
TLS2_k127_2398861_0 - - - - 0.0000000000000000000000000000000000000000000000001918 188.0
TLS2_k127_2398861_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000003439 173.0
TLS2_k127_2398861_2 HIT family hydrolase K02503 - - 0.000000000000000000000000000000001289 136.0
TLS2_k127_2398861_3 acetyltransferase - - - 0.000000000000000000001828 100.0
TLS2_k127_2398861_4 sequence-specific DNA binding K07726 - - 0.00000000000001576 74.0
TLS2_k127_2398861_5 - - - - 0.0000000006496 64.0
TLS2_k127_2398861_6 Redoxin - - - 0.00002135 54.0
TLS2_k127_2402118_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 1.105e-221 707.0
TLS2_k127_2402118_1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 572.0
TLS2_k127_2402118_2 formamidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 415.0
TLS2_k127_2402118_3 argininosuccinate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 342.0
TLS2_k127_2402118_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000007496 245.0
TLS2_k127_2402283_0 Protein of unknown function (DUF1549) - - - 2.61e-287 917.0
TLS2_k127_2402283_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 573.0
TLS2_k127_2402283_2 COG COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000001249 240.0
TLS2_k127_2402283_3 Carboxypeptidase regulatory-like domain - - - 0.000000009909 60.0
TLS2_k127_2405374_0 Glycosyltransferase Family 4 - - - 0.0 1300.0
TLS2_k127_2405374_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 9.726e-289 899.0
TLS2_k127_2405374_2 Sigma-54 interaction domain - - - 3.745e-271 844.0
TLS2_k127_2405374_3 beta-1,4-mannooligosaccharide phosphorylase - - - 1.105e-224 706.0
TLS2_k127_2405374_4 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 574.0
TLS2_k127_2405374_5 transferase activity, transferring glycosyl groups K00713,K06338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 537.0
TLS2_k127_2405374_6 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 331.0
TLS2_k127_2405374_7 photoreceptor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 316.0
TLS2_k127_2405374_8 Las17-binding protein actin regulator - - - 0.000000000000004121 82.0
TLS2_k127_2405374_9 - - - - 0.00000009259 56.0
TLS2_k127_2409837_0 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006391 279.0
TLS2_k127_2409837_1 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001291 274.0
TLS2_k127_2409837_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000004214 226.0
TLS2_k127_2409837_3 - - - - 0.0000000000000000000000000000000000000000000000000000002434 202.0
TLS2_k127_2409837_4 - - - - 0.000000000000000000000000000000000000000000001026 171.0
TLS2_k127_24207_0 amine dehydrogenase activity K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 539.0
TLS2_k127_24207_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 399.0
TLS2_k127_24207_2 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000002728 187.0
TLS2_k127_2434229_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 264.0
TLS2_k127_2434229_1 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000001641 199.0
TLS2_k127_2434229_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000185 181.0
TLS2_k127_2434229_3 Domain of unknown function (DUF4252) - - - 0.0000000000000000000000000000000000002288 147.0
TLS2_k127_2434229_4 - - - - 0.000001054 56.0
TLS2_k127_2446582_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.007e-294 911.0
TLS2_k127_2446582_1 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 465.0
TLS2_k127_2446582_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 348.0
TLS2_k127_2446582_3 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 335.0
TLS2_k127_2446582_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 321.0
TLS2_k127_2446582_5 - - - - 0.000000000000000002223 93.0
TLS2_k127_2446582_6 - - - - 0.000000000000000003776 89.0
TLS2_k127_2447526_0 Flavin containing amine oxidoreductase - - - 5.926e-251 782.0
TLS2_k127_2447526_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 2.384e-206 649.0
TLS2_k127_2447526_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 369.0
TLS2_k127_2447526_3 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 367.0
TLS2_k127_2447526_4 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 308.0
TLS2_k127_2447526_5 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000005391 259.0
TLS2_k127_2447526_6 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000002007 254.0
TLS2_k127_2447526_7 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000002334 124.0
TLS2_k127_2451205_0 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 398.0
TLS2_k127_2451205_1 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008993 261.0
TLS2_k127_2451205_2 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004388 267.0
TLS2_k127_2451205_3 SMART AAA ATPase - - - 0.0000000000000000000000000000000000000000000000345 172.0
TLS2_k127_2451205_4 - - - - 0.0001734 48.0
TLS2_k127_2458981_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 611.0
TLS2_k127_2458981_1 Glycosyl hydrolases family 43 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 494.0
TLS2_k127_2458981_2 PFAM Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000002522 59.0
TLS2_k127_2459168_0 TonB-dependent receptor - - - 0.0 1034.0
TLS2_k127_2459168_1 ASPIC and UnbV - - - 2.553e-213 676.0
TLS2_k127_2459168_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000004024 146.0
TLS2_k127_2459168_11 AhpC/TSA family - - - 0.000000000000000000000001142 107.0
TLS2_k127_2459168_12 Tetratricopeptide repeat - - - 0.00001173 56.0
TLS2_k127_2459168_2 Protein of unknown function (DUF1501) - - - 6.745e-196 620.0
TLS2_k127_2459168_3 Ribulose bisphosphate carboxylase large chain, N-terminal domain K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 564.0
TLS2_k127_2459168_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 539.0
TLS2_k127_2459168_5 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 435.0
TLS2_k127_2459168_6 Putative sugar-binding N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 431.0
TLS2_k127_2459168_7 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 363.0
TLS2_k127_2459168_8 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 330.0
TLS2_k127_2459168_9 FCD K22104 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004489 249.0
TLS2_k127_24617_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 329.0
TLS2_k127_24617_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000002051 194.0
TLS2_k127_2469328_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.289e-265 826.0
TLS2_k127_2469328_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.707e-200 646.0
TLS2_k127_2469328_2 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 619.0
TLS2_k127_2469328_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 429.0
TLS2_k127_2469328_4 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 416.0
TLS2_k127_2469328_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 373.0
TLS2_k127_2469328_6 VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000002144 230.0
TLS2_k127_2469328_7 4Fe-4S dicluster domain K05524 - - 0.00000000000000000000000000000000000000000001887 162.0
TLS2_k127_2469328_8 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000002602 119.0
TLS2_k127_2469328_9 nucleotide metabolic process - - - 0.0000000006119 60.0
TLS2_k127_2476010_0 Carboxypeptidase regulatory-like domain - - - 1.309e-202 661.0
TLS2_k127_2477827_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 3.558e-257 816.0
TLS2_k127_2477827_1 Cytochrome b(C-terminal)/b6/petD K00412 - - 4.316e-219 692.0
TLS2_k127_2477827_10 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000007312 196.0
TLS2_k127_2477827_11 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000000000000000000001101 198.0
TLS2_k127_2477827_12 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000001234 201.0
TLS2_k127_2477827_13 Rieske [2Fe-2S] domain K03886 - - 0.000000000000000000000000000000000000000000000000000127 192.0
TLS2_k127_2477827_14 pilus organization - - - 0.000000000000000000000000000000000000000000001263 176.0
TLS2_k127_2477827_2 Ammonium Transporter K03320 - - 5.164e-209 658.0
TLS2_k127_2477827_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 4.898e-202 639.0
TLS2_k127_2477827_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534,K17686 - 3.6.3.3,3.6.3.5,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 580.0
TLS2_k127_2477827_6 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 386.0
TLS2_k127_2477827_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 306.0
TLS2_k127_2477827_8 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 296.0
TLS2_k127_2477827_9 SPFH Band 7 PHB domain protein K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000001675 244.0
TLS2_k127_2483439_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 2.353e-263 820.0
TLS2_k127_2483439_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 515.0
TLS2_k127_2483439_2 CHRD domain - - - 0.00000000000000000000000004659 115.0
TLS2_k127_2483439_3 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000000002634 96.0
TLS2_k127_2499765_0 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 499.0
TLS2_k127_2499765_1 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 420.0
TLS2_k127_2499765_2 protein containing double-stranded beta helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002757 263.0
TLS2_k127_2507423_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2544.0
TLS2_k127_2507423_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 2.469e-242 751.0
TLS2_k127_2507423_2 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000006024 166.0
TLS2_k127_2507669_0 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 4.548e-213 673.0
TLS2_k127_2507669_1 ATPase domain of DNA mismatch repair MUTS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 568.0
TLS2_k127_2507669_2 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 411.0
TLS2_k127_2507669_3 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 379.0
TLS2_k127_2507669_4 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000001327 245.0
TLS2_k127_2507669_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000003318 176.0
TLS2_k127_2507669_6 - - - - 0.00000000000002377 80.0
TLS2_k127_2509075_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 351.0
TLS2_k127_2509075_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 328.0
TLS2_k127_2509075_2 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000001342 128.0
TLS2_k127_2509075_3 Calcineurin-like phosphoesterase - - - 0.000000002015 68.0
TLS2_k127_2510347_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 280.0
TLS2_k127_2510347_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001419 256.0
TLS2_k127_2510347_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000001483 219.0
TLS2_k127_2510347_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000001454 72.0
TLS2_k127_2511318_0 Ferrous iron transport protein B K04759 - - 9.054e-274 854.0
TLS2_k127_2511318_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.318e-268 860.0
TLS2_k127_2511318_10 DUF218 domain - - - 0.0000000000000000000006242 103.0
TLS2_k127_2511318_11 FeoA K04758 - - 0.000000000000000000001925 96.0
TLS2_k127_2511318_2 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 602.0
TLS2_k127_2511318_3 unsaturated chondroitin disaccharide hydrolase activity K18581 - 3.2.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 587.0
TLS2_k127_2511318_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 493.0
TLS2_k127_2511318_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003998 282.0
TLS2_k127_2511318_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000334 155.0
TLS2_k127_2511318_9 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000000000000002823 114.0
TLS2_k127_254272_0 TonB-dependent receptor - - - 1.786e-219 711.0
TLS2_k127_254272_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 571.0
TLS2_k127_254272_2 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 557.0
TLS2_k127_2551064_0 DDE (Asp,Asp,Glu) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 532.0
TLS2_k127_2551064_1 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 449.0
TLS2_k127_2551064_2 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 398.0
TLS2_k127_2551064_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003005 269.0
TLS2_k127_2551064_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000006367 245.0
TLS2_k127_2558470_0 TonB-dependent receptor - - - 0.0 1136.0
TLS2_k127_2558470_1 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 2.937e-277 862.0
TLS2_k127_2558470_2 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 617.0
TLS2_k127_2558470_3 Protein of unknown function (DUF1593) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 375.0
TLS2_k127_2558470_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 368.0
TLS2_k127_2558470_5 Penicillinase repressor - - - 0.00000000000000000000000000000006453 129.0
TLS2_k127_2558470_6 Putative collagen-binding domain of a collagenase - - - 0.00000000000000000000007097 102.0
TLS2_k127_2559815_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.072e-195 615.0
TLS2_k127_2559815_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 614.0
TLS2_k127_2559815_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 391.0
TLS2_k127_2559815_3 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 324.0
TLS2_k127_2559815_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000001023 232.0
TLS2_k127_2559815_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000008797 184.0
TLS2_k127_2559815_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000002865 143.0
TLS2_k127_2559815_7 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000001662 123.0
TLS2_k127_2577895_0 negative regulation of protein lipidation K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 410.0
TLS2_k127_2577895_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000000000000000002775 93.0
TLS2_k127_257900_0 PFAM Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 358.0
TLS2_k127_257900_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003024 255.0
TLS2_k127_257900_2 Psort location Cytoplasmic, score - - - 0.0000000000000005506 84.0
TLS2_k127_2592479_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 572.0
TLS2_k127_2592479_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 394.0
TLS2_k127_2592479_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 383.0
TLS2_k127_2592479_3 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 357.0
TLS2_k127_2592479_4 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006166 281.0
TLS2_k127_2592479_5 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001548 275.0
TLS2_k127_2592479_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001952 192.0
TLS2_k127_2592479_7 TM2 domain - - - 0.0000000000000000000000000000000000000000008985 161.0
TLS2_k127_2592479_8 Bacterial dnaA protein - - - 0.00000000000000000000000000000000000000005519 151.0
TLS2_k127_2602292_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 505.0
TLS2_k127_2602292_1 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 429.0
TLS2_k127_2602292_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 267.0
TLS2_k127_2602292_3 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000001027 240.0
TLS2_k127_2606962_0 hydrolase activity, hydrolyzing O-glycosyl compounds K05343 - 3.2.1.1,5.4.99.16 1.972e-211 670.0
TLS2_k127_2606962_1 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 489.0
TLS2_k127_2606962_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000006655 158.0
TLS2_k127_2606962_11 BON domain K04065 - - 0.000000000000003592 78.0
TLS2_k127_2606962_12 - - - - 0.0000000000001291 73.0
TLS2_k127_2606962_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 475.0
TLS2_k127_2606962_3 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 426.0
TLS2_k127_2606962_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 338.0
TLS2_k127_2606962_5 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 320.0
TLS2_k127_2606962_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003108 247.0
TLS2_k127_2606962_7 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000125 216.0
TLS2_k127_2606962_8 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000101 205.0
TLS2_k127_2606962_9 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000001027 175.0
TLS2_k127_2607363_0 Acyl transferase domain - - - 0.0 1217.0
TLS2_k127_2607363_1 CoA carboxylase activity K00627,K01176,K01966,K03646,K17489 - 2.1.3.1,2.1.3.15,2.3.1.12,3.2.1.1,6.4.1.3 0.000000000000000000004359 94.0
TLS2_k127_260837_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 503.0
TLS2_k127_260837_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000002491 70.0
TLS2_k127_260837_2 - - - - 0.00000000000377 70.0
TLS2_k127_260837_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000001128 61.0
TLS2_k127_2611666_0 lytic transglycosylase activity K08307,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 473.0
TLS2_k127_2611666_1 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 419.0
TLS2_k127_2611666_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 382.0
TLS2_k127_2611666_3 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 377.0
TLS2_k127_2611666_4 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 358.0
TLS2_k127_2611666_5 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 321.0
TLS2_k127_2611666_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000005331 197.0
TLS2_k127_2611666_7 Ureide permease K05340 - - 0.000000000000000000000000000000000000000000000007121 175.0
TLS2_k127_2611666_8 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000003199 147.0
TLS2_k127_2611666_9 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000007458 139.0
TLS2_k127_2643692_0 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 439.0
TLS2_k127_2643692_1 ROK family K00845,K00886,K01810 - 2.7.1.2,2.7.1.63,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 284.0
TLS2_k127_2643692_2 Tellurite resistance protein TehB - - - 0.0000000000000000000000000007993 126.0
TLS2_k127_2644211_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 2.407e-218 688.0
TLS2_k127_2644211_1 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 550.0
TLS2_k127_2644211_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000001825 230.0
TLS2_k127_2644211_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000009852 204.0
TLS2_k127_2644211_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001226 204.0
TLS2_k127_2644211_5 PFAM Response regulator receiver domain - - - 0.00000000001896 66.0
TLS2_k127_2649054_0 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 617.0
TLS2_k127_2649054_1 chemotaxis, protein K03406 - - 0.0000000000003439 78.0
TLS2_k127_2649054_2 STAS domain - - - 0.0002746 48.0
TLS2_k127_2650674_0 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 459.0
TLS2_k127_2650674_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000006199 99.0
TLS2_k127_2650674_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000005482 72.0
TLS2_k127_2654588_0 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 528.0
TLS2_k127_2654588_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000001014 103.0
TLS2_k127_2654588_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000004018 91.0
TLS2_k127_2654588_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000001892 83.0
TLS2_k127_2654588_4 Domain of unknown function (DUF4185) - - - 0.000000004605 60.0
TLS2_k127_2654588_5 PIN domain - - - 0.0000001197 55.0
TLS2_k127_2657785_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 508.0
TLS2_k127_2657785_1 enterobactin catabolic process K07214,K09689 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 503.0
TLS2_k127_2657785_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 388.0
TLS2_k127_2657785_3 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009727 362.0
TLS2_k127_2657785_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000001498 162.0
TLS2_k127_2657785_5 PFAM Fatty acid hydroxylase - - - 0.000000989 55.0
TLS2_k127_2658772_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 549.0
TLS2_k127_2658772_1 Alkaline phosphatase homologues K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 450.0
TLS2_k127_2658772_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 311.0
TLS2_k127_2658772_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000002828 177.0
TLS2_k127_2658772_4 PQQ-like domain - - - 0.000172 49.0
TLS2_k127_2660265_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
TLS2_k127_2660265_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 325.0
TLS2_k127_2660265_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000761 112.0
TLS2_k127_2670185_0 Carboxypeptidase regulatory-like domain - - - 0.0 1072.0
TLS2_k127_2670185_1 MacB-like periplasmic core domain - - - 5.966e-296 930.0
TLS2_k127_2670185_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 433.0
TLS2_k127_2694329_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 406.0
TLS2_k127_2694329_1 OsmC-like protein K04063 - - 0.000000000000000000000001821 102.0
TLS2_k127_2694329_2 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000005201 91.0
TLS2_k127_2694329_3 Amidohydrolase - - - 0.000000009394 63.0
TLS2_k127_2697108_0 Plasmid encoded RepA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 418.0
TLS2_k127_2697108_1 PFAM Transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 375.0
TLS2_k127_2697108_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000002828 173.0
TLS2_k127_2697108_3 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.000000000000000000000001243 111.0
TLS2_k127_269775_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.044e-221 703.0
TLS2_k127_269775_1 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 398.0
TLS2_k127_269775_2 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000000000000000000000000000000000006403 206.0
TLS2_k127_269775_3 ArsC family - - - 0.0000000000000000000000000000000000000003928 155.0
TLS2_k127_269775_4 MreB/Mbl protein - - - 0.000000000000000000008115 94.0
TLS2_k127_269775_5 - - - - 0.000000000000003028 82.0
TLS2_k127_269775_6 Outer membrane lipoprotein - - - 0.000000000000005922 77.0
TLS2_k127_2699181_0 COGs COG0673 dehydrogenase and related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 370.0
TLS2_k127_27132_0 transmembrane transporter activity K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 313.0
TLS2_k127_27132_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000009304 169.0
TLS2_k127_27132_2 Transposase, Mutator family - - - 0.0000000381 61.0
TLS2_k127_27132_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0003982 46.0
TLS2_k127_2716696_0 MacB-like periplasmic core domain - - - 2.542e-243 773.0
TLS2_k127_2716696_1 carboxylic acid catabolic process - - - 7.145e-199 629.0
TLS2_k127_2716696_2 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000007717 224.0
TLS2_k127_2716696_3 amine dehydrogenase activity - - - 0.000000000001736 78.0
TLS2_k127_2716696_4 - - - - 0.000002998 58.0
TLS2_k127_2717926_0 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000000004706 169.0
TLS2_k127_2717926_1 Helix-turn-helix domain - - - 0.00000000000000000000000001189 113.0
TLS2_k127_2717926_2 NHL repeat - - - 0.000357 50.0
TLS2_k127_2720430_0 CoA carboxylase activity K00627,K01176,K01966,K03646,K17489 - 2.1.3.1,2.1.3.15,2.3.1.12,3.2.1.1,6.4.1.3 0.0 2063.0
TLS2_k127_2720430_1 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000000000000000000000002996 161.0
TLS2_k127_2720912_0 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 519.0
TLS2_k127_2720912_1 Belongs to the IlvD Edd family - - - 0.00000000000000000000000000000000000000000000001197 173.0
TLS2_k127_2720912_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000001925 151.0
TLS2_k127_2720912_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000001096 134.0
TLS2_k127_2736661_0 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 608.0
TLS2_k127_2736661_1 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 554.0
TLS2_k127_2736661_2 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 331.0
TLS2_k127_2736661_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 316.0
TLS2_k127_2736661_4 Bacterial regulatory proteins, luxR family K03088 - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
TLS2_k127_2736661_5 - - - - 0.0000000000000002593 87.0
TLS2_k127_2739759_0 PIN domain K07063 - - 0.00000000000000000000000000000007783 128.0
TLS2_k127_2739759_1 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000000000000005427 98.0
TLS2_k127_2740111_0 hmm pf01609 - - - 0.000000000000000006258 87.0
TLS2_k127_2740111_1 Transposase domain (DUF772) - - - 0.00000000000000003174 87.0
TLS2_k127_2740111_2 Product type h extrachromosomal origin - - - 0.0000000003534 64.0
TLS2_k127_2740111_3 Transposase - - - 0.0002294 44.0
TLS2_k127_2745997_0 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 567.0
TLS2_k127_2745997_1 Protein of unknown function (DUF4236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 296.0
TLS2_k127_2745997_2 COG1226 Kef-type K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
TLS2_k127_2745997_3 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000223 256.0
TLS2_k127_2745997_4 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 234.0
TLS2_k127_2745997_5 PFAM biotin lipoyl attachment domain-containing protein K00382 - 1.8.1.4 0.00000000000000000000002081 99.0
TLS2_k127_2745997_6 DnaB-like helicase C terminal domain - - - 0.0000000000000001536 87.0
TLS2_k127_2745997_7 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000002902 61.0
TLS2_k127_2745997_8 iron dependent repressor - - - 0.00000001096 61.0
TLS2_k127_2750946_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 556.0
TLS2_k127_2750946_1 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 544.0
TLS2_k127_2750946_2 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 527.0
TLS2_k127_2750946_3 amidohydrolase K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 474.0
TLS2_k127_2750946_4 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 447.0
TLS2_k127_2750946_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 445.0
TLS2_k127_2750946_6 PFAM Squalene phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 396.0
TLS2_k127_2750946_7 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 405.0
TLS2_k127_2750946_8 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 348.0
TLS2_k127_2750946_9 other phosphorylase family 1 K01243 - 3.2.2.9 0.00000000000000003537 89.0
TLS2_k127_2770399_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1076.0
TLS2_k127_2770399_1 Response regulator receiver - - - 2.667e-205 647.0
TLS2_k127_2770399_2 PFAM Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 421.0
TLS2_k127_2770399_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 349.0
TLS2_k127_2770399_4 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 286.0
TLS2_k127_2773741_0 IS66 Orf2 like protein K07484 - - 0.000000000000000000000000000000000000000000000000001331 188.0
TLS2_k127_2773741_1 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.0000000007493 62.0
TLS2_k127_27745_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1118.0
TLS2_k127_27745_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1049.0
TLS2_k127_27745_10 cheY-homologous receiver domain - - - 0.000000000000000000000000000001319 129.0
TLS2_k127_27745_11 DinB superfamily - - - 0.00000000000000000004157 98.0
TLS2_k127_27745_12 Protein of unknown function (DUF2867) - - - 0.000000000000002609 80.0
TLS2_k127_27745_13 - - - - 0.0002089 49.0
TLS2_k127_27745_2 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 608.0
TLS2_k127_27745_3 'Molybdopterin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 525.0
TLS2_k127_27745_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 343.0
TLS2_k127_27745_5 photoreceptor activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 315.0
TLS2_k127_27745_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003396 264.0
TLS2_k127_27745_7 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000006166 202.0
TLS2_k127_27745_8 regulatory protein, MerR - - - 0.0000000000000000000000000000000003263 138.0
TLS2_k127_27745_9 PFAM Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000002275 134.0
TLS2_k127_2781526_0 cytochrome C - - - 1.615e-273 863.0
TLS2_k127_2781526_1 Dehydrogenase E1 component K11381 - 1.2.4.4 1.432e-238 745.0
TLS2_k127_2781526_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
TLS2_k127_2781676_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1487.0
TLS2_k127_2781676_1 4 iron, 4 sulfur cluster binding - - - 5.562e-211 671.0
TLS2_k127_2781676_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.034e-205 666.0
TLS2_k127_2781676_3 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 509.0
TLS2_k127_2782541_0 - - - - 0.0000000000000000000000000000000000000000000000000001144 202.0
TLS2_k127_2782541_1 - - - - 0.000000000000000000000000000000000000000001953 171.0
TLS2_k127_2782541_2 - - - - 0.0000000000000000000000000000004215 129.0
TLS2_k127_2782541_3 Protein of unknown function (DUF2283) - - - 0.000000000000000005501 85.0
TLS2_k127_2792356_0 virulence factor MVIN family protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 592.0
TLS2_k127_2792356_1 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 331.0
TLS2_k127_2792356_2 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 289.0
TLS2_k127_2792356_3 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001195 251.0
TLS2_k127_2796412_0 inositol 2-dehydrogenase activity - - - 7.62e-211 663.0
TLS2_k127_2796412_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 624.0
TLS2_k127_2796412_2 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 355.0
TLS2_k127_2796412_3 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 340.0
TLS2_k127_2796412_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002659 276.0
TLS2_k127_2796412_5 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000001555 216.0
TLS2_k127_2796412_6 PFAM Stage II sporulation protein E (SpoIIE) - - - 0.00000000000000000000000000000000000000000000000000000000621 214.0
TLS2_k127_2796412_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000002876 188.0
TLS2_k127_2796412_8 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000001765 168.0
TLS2_k127_2796412_9 - - - - 0.00000000000000005517 96.0
TLS2_k127_2805745_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K13832 - 1.1.1.25,4.2.1.10 4.28e-216 681.0
TLS2_k127_2805745_1 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 582.0
TLS2_k127_2805745_2 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 387.0
TLS2_k127_2805745_3 transporter - - - 0.000000000000000000000000000000000000000000000000005788 188.0
TLS2_k127_2805745_4 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000006597 136.0
TLS2_k127_2805745_5 BtpA family K06971 - - 0.000000000000001437 80.0
TLS2_k127_2805745_7 BtpA family K06971 - - 0.0003791 49.0
TLS2_k127_2814949_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 501.0
TLS2_k127_2814949_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 379.0
TLS2_k127_2814949_2 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000002808 158.0
TLS2_k127_2814949_3 cell redox homeostasis - - - 0.0000000000000000000000000000000000006298 147.0
TLS2_k127_2814949_4 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000004934 117.0
TLS2_k127_281869_0 Carboxypeptidase regulatory-like domain - - - 8.077e-210 690.0
TLS2_k127_281869_1 Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 396.0
TLS2_k127_281869_2 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 333.0
TLS2_k127_281869_3 - - - - 0.0000000000000000000000000000000000000000000000000000000007819 211.0
TLS2_k127_281869_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000001834 207.0
TLS2_k127_281869_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000004539 198.0
TLS2_k127_281869_7 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000002021 167.0
TLS2_k127_281869_9 Belongs to the IUNH family - - - 0.00000000000133 79.0
TLS2_k127_2822632_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.513e-216 680.0
TLS2_k127_2822632_1 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000009991 183.0
TLS2_k127_2822632_2 - - - - 0.0000000000000005271 83.0
TLS2_k127_2829085_0 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000006987 173.0
TLS2_k127_2829085_1 Transglycosylase associated protein - - - 0.000000000000000000000000003499 112.0
TLS2_k127_2829085_3 BON domain - - - 0.0000000000000000000006816 100.0
TLS2_k127_2829085_5 Hemerythrin - - - 0.000000003827 60.0
TLS2_k127_2829969_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 515.0
TLS2_k127_2829969_1 - - - - 0.000000000000000000000000000000008912 135.0
TLS2_k127_2830877_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 389.0
TLS2_k127_2830877_1 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007952 274.0
TLS2_k127_2830877_2 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000001458 187.0
TLS2_k127_2830877_3 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000003465 102.0
TLS2_k127_2830921_0 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 389.0
TLS2_k127_2830921_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 340.0
TLS2_k127_2830921_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 305.0
TLS2_k127_2830921_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
TLS2_k127_2830921_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000001895 144.0
TLS2_k127_2830921_5 Zinc-binding dehydrogenase - - - 0.000000000003251 68.0
TLS2_k127_2834634_0 TIGRFAM malto-oligosyltrehalose trehalohydrolase K00700 - 2.4.1.18 0.0 1099.0
TLS2_k127_2834634_1 Adenosine/AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 371.0
TLS2_k127_2834634_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000006617 254.0
TLS2_k127_2834634_3 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000003728 211.0
TLS2_k127_2836133_0 TIGRFAM ATP-dependent DNA helicase, RecQ family K03169,K03654 - 3.6.4.12,5.99.1.2 0.0 1618.0
TLS2_k127_2836133_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 507.0
TLS2_k127_2836133_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 497.0
TLS2_k127_2836133_3 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001326 261.0
TLS2_k127_2836133_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000311 220.0
TLS2_k127_2836133_5 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000009354 201.0
TLS2_k127_2836133_6 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000001992 155.0
TLS2_k127_2837978_0 PFAM Alcohol dehydrogenase GroES-like domain K00148 - 1.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 346.0
TLS2_k127_2837978_1 Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 321.0
TLS2_k127_2837978_2 PFAM transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000009749 206.0
TLS2_k127_2837978_3 Belongs to the 'phage' integrase family - - - 0.00002382 51.0
TLS2_k127_2838097_0 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 560.0
TLS2_k127_2838097_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 367.0
TLS2_k127_2838097_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 321.0
TLS2_k127_2838097_3 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000000000000000000004496 211.0
TLS2_k127_2838097_4 DinB superfamily - - - 0.0000000000000000007832 91.0
TLS2_k127_2843425_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 552.0
TLS2_k127_2843425_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000703 246.0
TLS2_k127_2843425_2 phosphorelay signal transduction system K02477,K07705,K21696 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000000000000004019 191.0
TLS2_k127_2843427_0 type II secretion system protein E K02283 - - 7.596e-210 659.0
TLS2_k127_2843427_1 Type II secretion system K12510 - - 0.00000000000000483 76.0
TLS2_k127_2846626_0 peptidase S9 - - - 8.409e-222 707.0
TLS2_k127_2846626_1 helicase activity - - - 4.302e-209 659.0
TLS2_k127_2846626_2 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 2.505e-203 647.0
TLS2_k127_2846626_3 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 580.0
TLS2_k127_2846626_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 427.0
TLS2_k127_2846626_5 DGC domain protein - - - 0.000000000000000000000000002173 117.0
TLS2_k127_2854505_0 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 3.118e-214 685.0
TLS2_k127_2859664_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000001265 222.0
TLS2_k127_2859664_1 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000009552 182.0
TLS2_k127_2859664_2 - - - - 0.0000000000000000000000000000000000000000004783 162.0
TLS2_k127_2859664_3 - - - - 0.0000000000000000000000000000000000000006336 158.0
TLS2_k127_2859664_4 - - - - 0.00000000000000000000000000001422 124.0
TLS2_k127_2859664_5 tRNA-splicing ligase RtcB - - - 0.00000000000000000000000002657 115.0
TLS2_k127_2860270_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 501.0
TLS2_k127_2860270_1 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 287.0
TLS2_k127_2860270_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000001196 177.0
TLS2_k127_2862276_0 Glycosyl hydrolase family 57 - - - 4.149e-264 827.0
TLS2_k127_2862276_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003289 270.0
TLS2_k127_2863943_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 463.0
TLS2_k127_2863943_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 375.0
TLS2_k127_2863943_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 331.0
TLS2_k127_2863943_3 glutathione-regulated potassium exporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 305.0
TLS2_k127_2863943_4 serine-type peptidase activity - - - 0.000000005425 66.0
TLS2_k127_2864579_0 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001019 271.0
TLS2_k127_2864579_1 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000003018 152.0
TLS2_k127_2864579_3 Reprolysin (M12B) family zinc metalloprotease - - - 0.000000004054 70.0
TLS2_k127_2864579_4 Parallel beta-helix repeats - - - 0.000000111 66.0
TLS2_k127_2865017_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 312.0
TLS2_k127_2865017_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000001352 181.0
TLS2_k127_2866171_0 transport - - - 1.374e-311 990.0
TLS2_k127_2866171_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 511.0
TLS2_k127_2866171_2 COG3119 Arylsulfatase A K01565 - 3.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 481.0
TLS2_k127_2866171_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 501.0
TLS2_k127_2866171_4 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001183 269.0
TLS2_k127_2866171_6 - - - - 0.00000000000000000000000000000006002 130.0
TLS2_k127_2866171_7 - - - - 0.000000000003827 70.0
TLS2_k127_2866332_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.665e-299 937.0
TLS2_k127_2866332_1 - - - - 4.907e-215 683.0
TLS2_k127_2866332_2 COG3119 Arylsulfatase A K01137 - 3.1.6.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 613.0
TLS2_k127_2866332_3 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 497.0
TLS2_k127_2866332_4 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 458.0
TLS2_k127_2866332_5 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 450.0
TLS2_k127_2866332_6 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 412.0
TLS2_k127_2866332_7 TonB-dependent receptor - - - 0.0000000000000000001292 91.0
TLS2_k127_2866596_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 607.0
TLS2_k127_2866596_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 553.0
TLS2_k127_2866596_10 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000001348 190.0
TLS2_k127_2866596_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000007211 184.0
TLS2_k127_2866596_12 photosynthesis K02656 - - 0.000000000000000000000000005786 120.0
TLS2_k127_2866596_14 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000000000522 106.0
TLS2_k127_2866596_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 546.0
TLS2_k127_2866596_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 372.0
TLS2_k127_2866596_4 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 304.0
TLS2_k127_2866596_5 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 291.0
TLS2_k127_2866596_6 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001899 259.0
TLS2_k127_2866596_7 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009406 255.0
TLS2_k127_2866596_8 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000006363 231.0
TLS2_k127_2866596_9 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000005268 210.0
TLS2_k127_2866776_0 N-acetyldiaminopimelate deacetylase activity K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 477.0
TLS2_k127_2866776_1 SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 396.0
TLS2_k127_2866776_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000097 191.0
TLS2_k127_2866776_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000008563 94.0
TLS2_k127_2866776_4 colicin V production K03558 - - 0.00000003499 62.0
TLS2_k127_2870593_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 484.0
TLS2_k127_2870593_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 389.0
TLS2_k127_2870593_2 Glycosyl transferase family group 2 K11740 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 307.0
TLS2_k127_2870593_3 Glycosyl transferase family group 2 K11740 - - 0.00000000000000000000000000000000000000000000000000000000000000007333 232.0
TLS2_k127_2870593_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000004127 48.0
TLS2_k127_2870593_5 DinB family - - - 0.00005823 51.0
TLS2_k127_2876549_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 570.0
TLS2_k127_2876549_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 488.0
TLS2_k127_2876549_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 327.0
TLS2_k127_2876549_3 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000001021 173.0
TLS2_k127_2876549_4 Memo-like protein K06990 - - 0.000000000000000000000000000000268 129.0
TLS2_k127_2877330_0 transport - - - 0.0 1326.0
TLS2_k127_2877330_1 Carboxypeptidase regulatory-like domain - - - 0.0 1164.0
TLS2_k127_2877330_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 479.0
TLS2_k127_2877330_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 348.0
TLS2_k127_2877330_4 transmembrane transporter activity K03535,K08194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001021 261.0
TLS2_k127_2877330_5 TonB dependent receptor K16087 - - 0.0000000000000000000000000000000000000000000000000000000000002671 240.0
TLS2_k127_2877330_6 transmembrane transporter activity K03535,K08194 - - 0.0000000000000000000000000000000000000000000000000000000009573 203.0
TLS2_k127_2877330_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000973 121.0
TLS2_k127_2877340_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1177.0
TLS2_k127_2877340_1 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 422.0
TLS2_k127_2878088_0 photoreceptor activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 293.0
TLS2_k127_2878088_1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000073 106.0
TLS2_k127_2878621_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 565.0
TLS2_k127_2878621_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 479.0
TLS2_k127_2878621_10 AcrB/AcrD/AcrF family K03296 - - 0.00000004283 54.0
TLS2_k127_2878621_2 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 398.0
TLS2_k127_2878621_3 - - - - 0.00000000000000000000000000000000000000002349 159.0
TLS2_k127_2878621_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000002293 108.0
TLS2_k127_2878621_5 Transposase - - - 0.0000000000000000000009833 96.0
TLS2_k127_2878621_6 phosphorelay signal transduction system - - - 0.000000000000000001925 92.0
TLS2_k127_2878621_7 - - - - 0.0000000000009776 70.0
TLS2_k127_2878621_8 DNA integration - - - 0.00000000003729 71.0
TLS2_k127_2878621_9 Transposase - - - 0.000000000144 71.0
TLS2_k127_2882612_0 Polyketide synthase of type I - - - 0.0 1062.0
TLS2_k127_2882612_1 lipase activity - - - 0.000000000000000000000000000000000000000000000000006843 190.0
TLS2_k127_2883906_0 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 604.0
TLS2_k127_2883906_1 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 398.0
TLS2_k127_2883906_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 345.0
TLS2_k127_2883906_3 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 308.0
TLS2_k127_2883906_4 inositol 2-dehydrogenase activity - - - 0.000004673 49.0
TLS2_k127_288456_1 Phage integrase family - - - 0.0000000000000004776 77.0
TLS2_k127_2885758_0 response to abiotic stimulus K03086,K06867,K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 532.0
TLS2_k127_2885758_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002157 302.0
TLS2_k127_2885758_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000002118 180.0
TLS2_k127_2885758_3 KaiB K08481 - - 0.00000000000000000000000000000000000000008044 154.0
TLS2_k127_2885758_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000001377 128.0
TLS2_k127_2885758_5 Pfam:KaiC K08482 - - 0.000003686 51.0
TLS2_k127_2885758_6 photoreceptor activity K08481 - - 0.0002582 46.0
TLS2_k127_2886923_0 Cytochrome c - - - 2.723e-257 812.0
TLS2_k127_2886923_1 Protein of unknown function (DUF1501) - - - 1.462e-202 638.0
TLS2_k127_2886923_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 450.0
TLS2_k127_2886923_3 Protein of unknown function (DUF1501) - - - 0.0000000000002486 69.0
TLS2_k127_2891972_0 FtsX-like permease family - - - 1.731e-218 702.0
TLS2_k127_2891972_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 325.0
TLS2_k127_2894221_0 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 484.0
TLS2_k127_2894221_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 429.0
TLS2_k127_2894221_2 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 345.0
TLS2_k127_2894221_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000001067 263.0
TLS2_k127_2894221_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000001025 197.0
TLS2_k127_2894221_5 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.000000000000000000000000000000000000000000000000004577 189.0
TLS2_k127_2894221_6 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000002707 140.0
TLS2_k127_2894221_7 Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.00000000000000000000000000000000008774 138.0
TLS2_k127_2894221_8 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000001204 127.0
TLS2_k127_2896220_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 556.0
TLS2_k127_2896220_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 434.0
TLS2_k127_2896220_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007817 257.0
TLS2_k127_2896220_3 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000001245 228.0
TLS2_k127_2897147_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 570.0
TLS2_k127_2897147_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 509.0
TLS2_k127_2897147_2 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002636 271.0
TLS2_k127_2897492_0 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 313.0
TLS2_k127_2897492_2 COG1331 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 0.000000257 62.0
TLS2_k127_2898168_0 carboxylic acid catabolic process K01706 - 4.2.1.40 4.904e-207 651.0
TLS2_k127_2898168_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 476.0
TLS2_k127_2898168_2 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 434.0
TLS2_k127_2898168_3 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 346.0
TLS2_k127_2898168_4 Predicted Peptidoglycan domain K17733 - - 0.00000000000000000000000000000000000000000000000001668 188.0
TLS2_k127_2898168_5 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000002346 157.0
TLS2_k127_2898168_6 Redoxin - - - 0.000000000000000000000000000000000003094 145.0
TLS2_k127_2898168_7 cell redox homeostasis K03671 - - 0.000000000000000000000000003082 118.0
TLS2_k127_2900302_0 3-isopropylmalate dehydrogenase activity K00030,K00031 - 1.1.1.41,1.1.1.42 3.346e-216 680.0
TLS2_k127_2900302_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 382.0
TLS2_k127_2900302_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000001126 242.0
TLS2_k127_2900302_3 SCO1/SenC K07152 - - 0.000000000001045 72.0
TLS2_k127_2905791_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.12e-202 640.0
TLS2_k127_2905791_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 601.0
TLS2_k127_2905791_2 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 383.0
TLS2_k127_2905791_3 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003295 261.0
TLS2_k127_2914345_0 - - - - 2.191e-309 961.0
TLS2_k127_2914345_1 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 309.0
TLS2_k127_2920000_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 339.0
TLS2_k127_2920000_1 two-component system sensor protein - - - 0.0000000000000000000000000000000007509 135.0
TLS2_k127_2922639_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 419.0
TLS2_k127_2922639_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001022 263.0
TLS2_k127_2922639_2 - - - - 0.000000000000000000002377 97.0
TLS2_k127_2922639_3 3D domain - - - 0.000000000000001137 83.0
TLS2_k127_2922772_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 468.0
TLS2_k127_2922772_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 366.0
TLS2_k127_2922772_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 322.0
TLS2_k127_2922772_3 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000001272 157.0
TLS2_k127_2922772_4 pathogenesis K01460 - 3.5.1.78,6.3.1.8 0.0000000000000000000000000001225 122.0
TLS2_k127_2933689_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000001929 195.0
TLS2_k127_2933689_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000004902 141.0
TLS2_k127_2933689_2 peptidyl-tyrosine sulfation - - - 0.000000000000000004285 93.0
TLS2_k127_2936963_0 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 308.0
TLS2_k127_2936963_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000007606 115.0
TLS2_k127_2936963_2 Fe-containing alcohol dehydrogenase K11173 - 1.1.99.24 0.00000005868 58.0
TLS2_k127_2938815_0 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 578.0
TLS2_k127_2938815_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 529.0
TLS2_k127_2938815_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 411.0
TLS2_k127_2938815_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002734 276.0
TLS2_k127_2938815_4 Tetratricopeptide repeats - - - 0.000003876 52.0
TLS2_k127_2939944_1 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000000000009087 129.0
TLS2_k127_2939944_2 phosphatase phosphohexomutase - - - 0.0000000000000000000000000002605 120.0
TLS2_k127_2939944_3 DJ-1/PfpI family - - - 0.00000000000009066 75.0
TLS2_k127_2943873_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 488.0
TLS2_k127_2943873_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006757 273.0
TLS2_k127_2943873_2 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005366 269.0
TLS2_k127_2943873_3 - - - - 0.00000000000000000001656 96.0
TLS2_k127_2943873_4 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.00000006261 64.0
TLS2_k127_2948334_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 446.0
TLS2_k127_2948334_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 353.0
TLS2_k127_2955780_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 580.0
TLS2_k127_2955780_1 WD40 domain protein beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 349.0
TLS2_k127_2955780_2 WD40 domain protein beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 346.0
TLS2_k127_2955780_3 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 308.0
TLS2_k127_2955780_4 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000001829 154.0
TLS2_k127_2955780_5 - - - - 0.0000000008953 68.0
TLS2_k127_2955780_6 Tetratricopeptide repeat - - - 0.0008684 44.0
TLS2_k127_2972388_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 608.0
TLS2_k127_2972388_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 296.0
TLS2_k127_2972388_2 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000001175 176.0
TLS2_k127_2974365_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 453.0
TLS2_k127_2974365_1 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 359.0
TLS2_k127_2974365_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001244 273.0
TLS2_k127_2974365_3 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000004357 216.0
TLS2_k127_2989949_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1147.0
TLS2_k127_2989949_1 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 489.0
TLS2_k127_2989949_2 PFAM small multidrug resistance protein K11741 - - 0.000000000000000000000000001637 122.0
TLS2_k127_2995230_0 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 595.0
TLS2_k127_2995230_1 RAMP superfamily K09002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 425.0
TLS2_k127_2995230_2 crispr-associated protein K07016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 405.0
TLS2_k127_2995230_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 339.0
TLS2_k127_2995230_4 Csm2 Type III-A K19138 - - 0.0000000000000000000000000000000000000000000000000000000000006603 216.0
TLS2_k127_2995230_5 CRISPR-associated RAMP protein, Csm4 family - - - 0.00000000000000000000000000000000000000003909 155.0
TLS2_k127_2995855_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 606.0
TLS2_k127_2995855_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 589.0
TLS2_k127_300002_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 366.0
TLS2_k127_300002_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 347.0
TLS2_k127_300002_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 292.0
TLS2_k127_300002_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000001142 193.0
TLS2_k127_300002_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000004593 141.0
TLS2_k127_300002_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000006531 100.0
TLS2_k127_3003840_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 439.0
TLS2_k127_3003840_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 375.0
TLS2_k127_3003840_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000002528 226.0
TLS2_k127_3003840_3 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000002322 213.0
TLS2_k127_3003840_4 HD domain - - - 0.00000000000000000000000000000003379 143.0
TLS2_k127_3008836_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 514.0
TLS2_k127_3008836_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 469.0
TLS2_k127_3008836_2 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 385.0
TLS2_k127_3008836_3 PFAM Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 0.00008068 48.0
TLS2_k127_3022733_0 Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 424.0
TLS2_k127_3023239_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1745.0
TLS2_k127_3023239_1 Putative glucoamylase - - - 1.204e-204 646.0
TLS2_k127_3023239_2 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 582.0
TLS2_k127_3023239_3 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 537.0
TLS2_k127_3023239_4 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 401.0
TLS2_k127_3023239_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 299.0
TLS2_k127_3024992_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 485.0
TLS2_k127_3024992_1 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000001162 153.0
TLS2_k127_3024992_2 Trehalose utilisation - - - 0.000000000000000000000000000000000002091 143.0
TLS2_k127_3024992_3 - - - - 0.00005127 46.0
TLS2_k127_3032250_0 Cytochrome c, class I - - - 5.891e-287 897.0
TLS2_k127_3032250_1 Protein of unknown function (DUF1501) - - - 1.242e-228 715.0
TLS2_k127_3032250_2 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 406.0
TLS2_k127_3032250_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 290.0
TLS2_k127_3032250_4 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000001701 211.0
TLS2_k127_3032250_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000299 202.0
TLS2_k127_3032250_6 Domain of unknown function (DUF892) - - - 0.00000000000000000000000000000000000001242 158.0
TLS2_k127_3032250_7 - - - - 0.000000000000000000000000000000000002285 151.0
TLS2_k127_3032287_0 DNA polymerase X K02347 - - 8.766e-261 813.0
TLS2_k127_3032287_1 D-galactarate dehydratase / Altronate hydrolase, C terminus K01708 - 4.2.1.42 1.288e-230 723.0
TLS2_k127_3032287_2 Beta-Ig-H3 fasciclin - - - 0.0000000000000000000000000000000000000000000000000867 187.0
TLS2_k127_3032287_3 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000004296 147.0
TLS2_k127_3037981_0 Sigma-54 interaction domain - - - 4.605e-220 702.0
TLS2_k127_3037981_1 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 349.0
TLS2_k127_3037981_2 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000004474 219.0
TLS2_k127_3037981_3 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000002764 216.0
TLS2_k127_3037981_4 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000007596 136.0
TLS2_k127_3040056_0 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 535.0
TLS2_k127_3040056_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 331.0
TLS2_k127_3053774_0 DNA topological change - - - 0.0 1056.0
TLS2_k127_3053774_1 Protein of unknown function (DUF1552) - - - 2.337e-228 714.0
TLS2_k127_3053774_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 470.0
TLS2_k127_3053774_3 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 436.0
TLS2_k127_3053774_4 eRF1 domain 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 427.0
TLS2_k127_3053774_5 ribosylpyrimidine nucleosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 321.0
TLS2_k127_3053774_6 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000001387 256.0
TLS2_k127_3053774_7 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000004438 222.0
TLS2_k127_3053774_8 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000003195 180.0
TLS2_k127_3053774_9 ECF sigma factor - - - 0.00000000000000000000000000000003703 132.0
TLS2_k127_3054217_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 617.0
TLS2_k127_3054217_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002467 288.0
TLS2_k127_3054217_2 Carboxypeptidase regulatory-like domain - - - 0.000001425 55.0
TLS2_k127_305506_0 Alpha-L-fucosidase K01206 - 3.2.1.51 2.593e-282 887.0
TLS2_k127_305506_1 Trehalase K01194 GO:0003674,GO:0003824,GO:0004553,GO:0004555,GO:0005975,GO:0005984,GO:0005991,GO:0005993,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009628,GO:0009987,GO:0015927,GO:0016052,GO:0016787,GO:0016798,GO:0033554,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0050896,GO:0051716,GO:0071214,GO:0071470,GO:0071474,GO:0071704,GO:0104004,GO:1901575 3.2.1.28 7.27e-254 792.0
TLS2_k127_305506_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 417.0
TLS2_k127_305506_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 287.0
TLS2_k127_305506_4 Arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000177 273.0
TLS2_k127_305506_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000004676 193.0
TLS2_k127_305506_6 SnoaL-like domain - - - 0.000000000000000000000000000000000000000003172 162.0
TLS2_k127_3057668_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 545.0
TLS2_k127_3057668_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000003416 227.0
TLS2_k127_3057668_2 Polysaccharide lyase family 4, domain III - - - 0.00000000000000000000000000000000000000000001591 185.0
TLS2_k127_3058489_0 transport - - - 3.328e-244 794.0
TLS2_k127_3058489_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 5.226e-217 685.0
TLS2_k127_3058489_2 aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 552.0
TLS2_k127_3058489_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 484.0
TLS2_k127_3058489_4 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000002444 195.0
TLS2_k127_3058489_5 Domain of unknown function (DUF1972) - - - 0.000000000000000000000000000000000000000000000000000006318 192.0
TLS2_k127_3058489_6 - - - - 0.00000000000000000001195 98.0
TLS2_k127_305946_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 497.0
TLS2_k127_305946_1 - - - - 0.000000000002235 74.0
TLS2_k127_3065721_0 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 555.0
TLS2_k127_3065721_1 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000006522 211.0
TLS2_k127_3065721_2 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000001654 158.0
TLS2_k127_3065721_3 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000001724 93.0
TLS2_k127_3065721_4 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000001356 75.0
TLS2_k127_3071836_0 Recombinase zinc beta ribbon domain K06400 - - 4.37e-208 663.0
TLS2_k127_3071836_1 Group II intron, maturase-specific domain K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000027 194.0
TLS2_k127_3071836_2 transposase activity K07497 - - 0.0000000000000000000000000000000000000000000000004817 180.0
TLS2_k127_3071836_3 Ribbon-helix-helix protein, copG family - - - 0.00000000001028 69.0
TLS2_k127_3071836_4 Resolvase domain - - - 0.00001072 49.0
TLS2_k127_30739_0 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 422.0
TLS2_k127_30739_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 295.0
TLS2_k127_30739_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009754 242.0
TLS2_k127_30739_3 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.00000000000000000000000000000000000000002972 156.0
TLS2_k127_30739_4 - - - - 0.000001058 59.0
TLS2_k127_307637_0 carboxylic acid catabolic process K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 443.0
TLS2_k127_307637_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 393.0
TLS2_k127_307637_2 Hep Hag repeat protein - - - 0.0000000000000000002466 103.0
TLS2_k127_3077445_0 amine dehydrogenase activity K14647,K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 573.0
TLS2_k127_3077445_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009538 299.0
TLS2_k127_3077445_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000002872 68.0
TLS2_k127_3078759_0 Isocitrate lyase family K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 602.0
TLS2_k127_3078759_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 535.0
TLS2_k127_309588_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 522.0
TLS2_k127_309588_1 TIGRFAM efflux transporter, RND family, MFP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 472.0
TLS2_k127_309588_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009779 405.0
TLS2_k127_309588_3 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 366.0
TLS2_k127_309588_4 Transcriptional regulator K07979 - - 0.000000000000002461 76.0
TLS2_k127_309588_5 - - - - 0.00000000006993 72.0
TLS2_k127_3096149_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 496.0
TLS2_k127_3096149_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000004583 194.0
TLS2_k127_3096149_2 Globin - - - 0.0000000007086 61.0
TLS2_k127_3103166_0 PFAM Peptidase M16 K07263 - - 4.016e-198 636.0
TLS2_k127_3103166_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 382.0
TLS2_k127_3103166_2 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 363.0
TLS2_k127_3103166_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000001787 80.0
TLS2_k127_3103562_0 Carboxypeptidase regulatory-like domain - - - 9.641e-197 653.0
TLS2_k127_3103562_1 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 442.0
TLS2_k127_3103562_2 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 329.0
TLS2_k127_3103562_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003791 269.0
TLS2_k127_3103562_4 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000003096 246.0
TLS2_k127_3107497_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000005756 162.0
TLS2_k127_3107497_1 negative regulation of translational initiation - - - 0.000595 50.0
TLS2_k127_3107497_2 Aminotransferase class I and II K14155 - 4.4.1.8 0.000686 44.0
TLS2_k127_3109032_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000006577 211.0
TLS2_k127_3109032_1 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000005164 171.0
TLS2_k127_3123279_0 succinate dehydrogenase - - - 3.123e-233 736.0
TLS2_k127_3123279_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001507 253.0
TLS2_k127_3123279_2 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000002422 210.0
TLS2_k127_3123279_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000004143 162.0
TLS2_k127_3124524_0 Glutamate synthase K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.7.1 0.0 1116.0
TLS2_k127_3124524_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.56e-242 755.0
TLS2_k127_3124524_2 amine dehydrogenase activity - - - 0.000000002507 70.0
TLS2_k127_3124524_3 Domain of unknown function (DUF4214) - - - 0.00001345 58.0
TLS2_k127_3132829_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 483.0
TLS2_k127_3132829_1 repeat-containing protein - - - 0.0000008224 61.0
TLS2_k127_3132829_2 DNA-templated transcription, initiation K03088 - - 0.0001275 51.0
TLS2_k127_3134338_0 Cytochrome c - - - 0.0 1103.0
TLS2_k127_3134338_1 Protein of unknown function (DUF1553) - - - 3.765e-235 753.0
TLS2_k127_3134338_2 long-chain fatty acid transporting porin activity - - - 4.778e-212 668.0
TLS2_k127_3134338_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000006557 181.0
TLS2_k127_313654_0 Glycosyl hydrolase family 115 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 587.0
TLS2_k127_313654_1 transmembrane transporter activity K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 346.0
TLS2_k127_313654_2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain K20022 - 4.2.1.158 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 295.0
TLS2_k127_313654_3 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000003005 252.0
TLS2_k127_313654_4 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000000000000000002068 228.0
TLS2_k127_313654_5 KR domain - - - 0.00000000000000000000000000000000000000001242 171.0
TLS2_k127_3140962_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 601.0
TLS2_k127_3140962_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000001054 200.0
TLS2_k127_3140962_2 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00000000000000000000000000000000000000000000000421 180.0
TLS2_k127_3141306_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 275.0
TLS2_k127_3141306_1 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000001973 240.0
TLS2_k127_3141306_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000002627 237.0
TLS2_k127_3141306_3 Allophanate hydrolase, subunit 1 - - - 0.00000000000000000000000000000000000000000000000004617 186.0
TLS2_k127_3141306_4 Recombinase - - - 0.0000000000000000000000003655 111.0
TLS2_k127_3141306_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000001055 113.0
TLS2_k127_3156142_0 Glycosyl transferase, family 2 - - - 2.421e-251 803.0
TLS2_k127_3156142_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.052e-247 775.0
TLS2_k127_3156142_2 Highly conserved protein containing a thioredoxin domain K06888,K20948 - - 0.000000000000000000000000000003577 124.0
TLS2_k127_3157836_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 459.0
TLS2_k127_3157836_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000007332 256.0
TLS2_k127_3157836_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000002977 221.0
TLS2_k127_3158345_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 416.0
TLS2_k127_3158345_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000004475 154.0
TLS2_k127_3158345_2 domain-containing protein - - - 0.0000000000007461 79.0
TLS2_k127_3159367_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 464.0
TLS2_k127_3159367_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 375.0
TLS2_k127_3159367_2 DinB family - - - 0.000000000000000000000000000000000000000000002295 173.0
TLS2_k127_3159367_3 AI-2E family transporter - - - 0.000000000000000000000000000000000002585 153.0
TLS2_k127_3159367_4 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.000000000000000000000000000000000007461 153.0
TLS2_k127_3159367_5 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000001166 102.0
TLS2_k127_3165578_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 580.0
TLS2_k127_3165578_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 470.0
TLS2_k127_3165578_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 448.0
TLS2_k127_3165578_3 PFAM IstB domain protein ATP-binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 406.0
TLS2_k127_3165578_4 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 364.0
TLS2_k127_3166491_0 PP-loop family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 415.0
TLS2_k127_3166491_1 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 384.0
TLS2_k127_3166491_2 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 305.0
TLS2_k127_3166491_3 VWA domain containing CoxE-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 301.0
TLS2_k127_3166491_4 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006778 248.0
TLS2_k127_3167491_0 WD40 domain protein beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 379.0
TLS2_k127_3167491_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000004117 155.0
TLS2_k127_3169768_0 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 612.0
TLS2_k127_3169768_1 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 420.0
TLS2_k127_3170715_0 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 619.0
TLS2_k127_3170715_1 - - - - 0.000000000000000000000000000000000000127 150.0
TLS2_k127_3171807_0 Transposase K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 559.0
TLS2_k127_3171807_1 Transposase - - - 0.0000000000000000000000000000000000000000000002782 168.0
TLS2_k127_3171807_2 - - - - 0.0001568 48.0
TLS2_k127_3173781_0 Cytochrome c554 and c-prime - - - 0.0 1126.0
TLS2_k127_3173781_1 ASPIC and UnbV - - - 1.109e-252 789.0
TLS2_k127_3173781_10 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000168 164.0
TLS2_k127_3173781_11 Chromate transporter K07240 - - 0.0000000000000000000000000000000000004274 151.0
TLS2_k127_3173781_12 Chromate transporter K07240 - - 0.000000000000000000009408 100.0
TLS2_k127_3173781_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 584.0
TLS2_k127_3173781_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 528.0
TLS2_k127_3173781_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 464.0
TLS2_k127_3173781_5 Myo-inositol oxygenase K00469 - 1.13.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 434.0
TLS2_k127_3173781_6 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007015 266.0
TLS2_k127_3173781_7 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001052 273.0
TLS2_k127_3173781_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000001602 248.0
TLS2_k127_3173781_9 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.0000000000000000000000000000000000000000000000004146 178.0
TLS2_k127_3174565_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000005266 165.0
TLS2_k127_3174565_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000000000000001161 133.0
TLS2_k127_3174565_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000001596 102.0
TLS2_k127_3174565_3 antisigma factor binding K04749 - - 0.00000000000000005291 85.0
TLS2_k127_317538_0 efflux transmembrane transporter activity - - - 1.012e-210 677.0
TLS2_k127_317538_1 peptidyl-tyrosine sulfation - - - 0.0000000000005601 75.0
TLS2_k127_3177987_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 343.0
TLS2_k127_3177987_1 Manganese containing catalase K07217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 312.0
TLS2_k127_3177987_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001765 188.0
TLS2_k127_3178672_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1074.0
TLS2_k127_3178672_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
TLS2_k127_3178672_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000001632 127.0
TLS2_k127_3178672_4 SnoaL-like domain - - - 0.0000000000000000001281 93.0
TLS2_k127_3179029_0 Resolvase domain - - - 9.945e-230 719.0
TLS2_k127_3179029_1 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000005674 182.0
TLS2_k127_3179029_2 Family of unknown function (DUF5372) - - - 0.000000000000000000008783 95.0
TLS2_k127_3179029_3 PFAM Integrase catalytic region - - - 0.0000000001711 62.0
TLS2_k127_3179668_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 435.0
TLS2_k127_3179808_0 Dehydrogenase K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000002302 216.0
TLS2_k127_3179808_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000008301 146.0
TLS2_k127_3179909_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 573.0
TLS2_k127_3179909_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 399.0
TLS2_k127_3179909_2 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 320.0
TLS2_k127_3179909_3 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000001163 181.0
TLS2_k127_3179909_4 Methane oxygenase PmoA - - - 0.000000000000000000000000001661 121.0
TLS2_k127_3180502_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 604.0
TLS2_k127_3180502_1 phosphorelay sensor kinase activity - - - 0.000000000000000000000000002115 112.0
TLS2_k127_3181603_0 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 336.0
TLS2_k127_3181603_1 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000008244 252.0
TLS2_k127_3181603_2 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000003922 169.0
TLS2_k127_3181603_3 DinB family - - - 0.00000000000000000000000000000000000000000006812 165.0
TLS2_k127_3181603_4 Membrane - - - 0.0000000001249 63.0
TLS2_k127_3182827_0 Domain of unknown function (DUF5060) - - - 8.395e-200 658.0
TLS2_k127_3182827_1 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 437.0
TLS2_k127_3182827_2 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 338.0
TLS2_k127_3182827_3 PFAM Lytic transglycosylase catalytic - - - 0.0000000000000000000000000000000000000000000000004407 187.0
TLS2_k127_3182827_4 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000664 86.0
TLS2_k127_3182827_5 Phenazine biosynthesis-like protein - - - 0.0000000004657 60.0
TLS2_k127_3184941_0 Metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 295.0
TLS2_k127_3184941_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000314 192.0
TLS2_k127_3184941_2 InterPro IPR007367 - - - 0.0000000000000000000000000000000000007878 139.0
TLS2_k127_3184941_3 Integrase - - - 0.000000000000000000002627 95.0
TLS2_k127_3184941_4 - - - - 0.0000000000000007273 83.0
TLS2_k127_3184941_5 Protein of unknown function (DUF3237) - - - 0.00001479 50.0
TLS2_k127_3185243_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.605e-288 899.0
TLS2_k127_3185243_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.764e-236 746.0
TLS2_k127_3185243_2 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000000000000000000000006442 205.0
TLS2_k127_3185243_3 Glucose-6-phosphate dehydrogenase subunit - - - 0.0000000000000000000000000000000000000000000000000000002077 202.0
TLS2_k127_3185243_4 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000001596 168.0
TLS2_k127_3185243_5 membrane K00860,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000000003671 94.0
TLS2_k127_3185480_0 Belongs to the malate synthase family K01638 - 2.3.3.9 7.961e-229 719.0
TLS2_k127_3185480_1 Protein of unknown function (DUF4038) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 542.0
TLS2_k127_3185480_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 462.0
TLS2_k127_3185480_3 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 418.0
TLS2_k127_3185480_4 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000003449 179.0
TLS2_k127_3185480_5 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000009221 162.0
TLS2_k127_3185480_6 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000001734 65.0
TLS2_k127_3187677_0 PFAM Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 611.0
TLS2_k127_3187677_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 499.0
TLS2_k127_3187677_2 Protein of unknown function (DUF1553) - - - 0.00000000000000007564 86.0
TLS2_k127_3189195_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 441.0
TLS2_k127_3189195_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 342.0
TLS2_k127_3189195_2 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 346.0
TLS2_k127_3189195_3 RsgA GTPase K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 291.0
TLS2_k127_3189195_4 Penicillinase repressor - - - 0.00000000000000000000000000000000000000009213 154.0
TLS2_k127_3189195_5 Transcriptional regulator K07979 - - 0.00000000000000000000376 96.0
TLS2_k127_3189195_6 - - - - 0.000000000000007011 88.0
TLS2_k127_3189195_7 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 0.00003737 50.0
TLS2_k127_3190038_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 400.0
TLS2_k127_3190038_1 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 291.0
TLS2_k127_3190038_2 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 289.0
TLS2_k127_3190038_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001133 246.0
TLS2_k127_3192069_0 cAMP biosynthetic process K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 458.0
TLS2_k127_3192069_1 Belongs to the ompA family - - - 0.0000000000000000000000000000000002672 143.0
TLS2_k127_3192069_2 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.00000000000000000000000000006384 124.0
TLS2_k127_3192069_3 WD40 domain protein beta Propeller - - - 0.000000000000000000000000006029 128.0
TLS2_k127_3192069_5 PFAM Tetratricopeptide - - - 0.0000000000000006589 88.0
TLS2_k127_3195562_0 Nacht domain - - - 1.601e-265 870.0
TLS2_k127_3195562_1 - - - - 0.0000000000006743 69.0
TLS2_k127_3195562_2 Protein of unknown function (DUF2283) - - - 0.000000000009657 66.0
TLS2_k127_3195562_3 Phage integrase family - - - 0.00003284 48.0
TLS2_k127_3212165_0 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 388.0
TLS2_k127_3214153_0 efflux transmembrane transporter activity K02004 - - 2.761e-207 651.0
TLS2_k127_3214153_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 587.0
TLS2_k127_3214153_2 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 598.0
TLS2_k127_3214153_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 535.0
TLS2_k127_3214153_4 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 513.0
TLS2_k127_3214153_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001109 275.0
TLS2_k127_3214153_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000007599 198.0
TLS2_k127_3214153_8 RES - - - 0.000000000000000000000000000000000000000000003667 168.0
TLS2_k127_3214153_9 Protein of unknown function (DUF2384) - - - 0.000000000000000000004673 102.0
TLS2_k127_3218301_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 613.0
TLS2_k127_3218301_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.0000000000000000000000000000000000000000000000000000522 196.0
TLS2_k127_3218301_2 CAP-associated N-terminal - - - 0.0000000000000000000001199 105.0
TLS2_k127_3223936_0 Glycosyl hydrolase catalytic core - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 475.0
TLS2_k127_3223936_1 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 370.0
TLS2_k127_3223936_2 thiamine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 371.0
TLS2_k127_3223936_3 Putative zinc- or iron-chelating domain - - - 0.00000000000000003975 89.0
TLS2_k127_3228437_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.429e-208 657.0
TLS2_k127_3228437_1 spore germination K08978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 512.0
TLS2_k127_3228437_2 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 505.0
TLS2_k127_3228437_3 myo-inosose-2 dehydratase activity K00010,K03335 - 1.1.1.18,1.1.1.369,4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 466.0
TLS2_k127_3228437_4 Belongs to the TPP enzyme family K03336 GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 0.000000000000000000000000000000000000000000002854 168.0
TLS2_k127_3228437_5 Protein of unknown function (DUF1501) - - - 0.0000000000000000002048 88.0
TLS2_k127_3240013_0 radical SAM domain protein K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 565.0
TLS2_k127_3240013_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 546.0
TLS2_k127_3240013_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 522.0
TLS2_k127_3240013_3 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 420.0
TLS2_k127_3240013_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 364.0
TLS2_k127_3240013_5 - - - - 0.000000000000000000000000000000000000000000000002467 185.0
TLS2_k127_3240013_6 - - - - 0.00000000000000000000000000000000000002458 159.0
TLS2_k127_3240013_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000002167 151.0
TLS2_k127_3240013_8 - - - - 0.000000000000000000000000000000006329 136.0
TLS2_k127_3241279_0 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 2.655e-235 744.0
TLS2_k127_3241279_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 389.0
TLS2_k127_3258523_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 7.383e-236 740.0
TLS2_k127_3258523_1 PFAM Redoxin - - - 0.000000000000000000000000000000000000000000000003008 182.0
TLS2_k127_3258523_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000007836 166.0
TLS2_k127_3258523_3 transposase activity K07483,K07497 - - 0.00000000000000000455 90.0
TLS2_k127_3258523_4 transposition - - - 0.00000000000166 74.0
TLS2_k127_3258523_5 positive regulation of growth - - - 0.0008134 46.0
TLS2_k127_3261714_0 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000004947 187.0
TLS2_k127_3261714_1 CHAD - - - 0.0000000000000001634 86.0
TLS2_k127_3264224_0 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 370.0
TLS2_k127_3264224_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 338.0
TLS2_k127_3265873_0 Belongs to the xylose isomerase family K01805 - 5.3.1.5 5.363e-208 655.0
TLS2_k127_3265873_1 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002532 267.0
TLS2_k127_3265873_2 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000006671 233.0
TLS2_k127_3266787_0 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 402.0
TLS2_k127_3266787_1 arylsulfatase activity - - - 0.00000000000000000000000000002247 127.0
TLS2_k127_3266787_2 Putative cyclase - - - 0.0000000000000003322 83.0
TLS2_k127_3267383_0 Cytochrome c - - - 1.053e-226 711.0
TLS2_k127_3267383_1 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 281.0
TLS2_k127_3270529_0 ArgK protein K07588 GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 455.0
TLS2_k127_3270529_1 acetyl-CoA hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000001374 228.0
TLS2_k127_3270529_2 cobalamin binding K01847,K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000741 211.0
TLS2_k127_3271126_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 548.0
TLS2_k127_3271126_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 402.0
TLS2_k127_3271126_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 297.0
TLS2_k127_3271126_3 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000006112 244.0
TLS2_k127_3271126_4 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000739 78.0
TLS2_k127_3271126_5 - - - - 0.0000003934 57.0
TLS2_k127_3291248_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 414.0
TLS2_k127_3291248_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000003596 211.0
TLS2_k127_3291248_2 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000006948 209.0
TLS2_k127_3294381_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.95e-302 938.0
TLS2_k127_3294381_1 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 351.0
TLS2_k127_3294381_2 plasmid maintenance K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 343.0
TLS2_k127_3294381_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 346.0
TLS2_k127_3294381_4 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 297.0
TLS2_k127_3294381_5 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000838 203.0
TLS2_k127_3294381_6 CHAT domain - - - 0.0000000000000397 84.0
TLS2_k127_3294381_7 phosphorelay signal transduction system - - - 0.00000003386 61.0
TLS2_k127_3294381_8 PAS fold - - - 0.0001056 49.0
TLS2_k127_3294744_0 PFAM type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 614.0
TLS2_k127_3294744_1 cobalamin-transporting ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 595.0
TLS2_k127_3294744_10 - - - - 0.00000000000000000000000000000005079 128.0
TLS2_k127_3294744_11 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000000000000000000002831 112.0
TLS2_k127_3294744_12 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000006916 108.0
TLS2_k127_3294744_13 His Kinase A (phosphoacceptor) domain - - - 0.0000000000003316 83.0
TLS2_k127_3294744_14 - K05826 - - 0.00000000004012 66.0
TLS2_k127_3294744_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 330.0
TLS2_k127_3294744_3 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 309.0
TLS2_k127_3294744_4 type II secretion system K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001053 262.0
TLS2_k127_3294744_5 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003963 253.0
TLS2_k127_3294744_6 type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000007253 245.0
TLS2_k127_3294744_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000003165 216.0
TLS2_k127_3294744_8 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000137 192.0
TLS2_k127_3294744_9 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000103 146.0
TLS2_k127_3295407_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1101.0
TLS2_k127_3295407_1 Alginate export - - - 0.0000000000000000000000000000001343 133.0
TLS2_k127_3295420_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 484.0
TLS2_k127_3295420_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.00000000000000000000000000000000000000271 150.0
TLS2_k127_3300489_0 AcrB/AcrD/AcrF family - - - 0.0 1695.0
TLS2_k127_3300489_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1210.0
TLS2_k127_3300489_2 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 493.0
TLS2_k127_3300489_3 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 398.0
TLS2_k127_3300489_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 294.0
TLS2_k127_3300489_5 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000001381 227.0
TLS2_k127_3300489_6 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000005755 168.0
TLS2_k127_3313575_0 Dehydratase family K22186 - 4.2.1.82 1.245e-219 693.0
TLS2_k127_3313575_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 370.0
TLS2_k127_3315619_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 619.0
TLS2_k127_3315619_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 287.0
TLS2_k127_3315619_2 Phage integrase family - - - 0.00000000000000000000000000006993 118.0
TLS2_k127_3315619_3 determination of stomach left/right asymmetry K10407 - - 0.0002039 47.0
TLS2_k127_3320057_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 485.0
TLS2_k127_3320057_1 -O-antigen K02847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 392.0
TLS2_k127_3320057_2 DinB family - - - 0.00000000000000000000000646 104.0
TLS2_k127_3320057_3 extracellular polysaccharide biosynthetic process K01153 - 3.1.21.3 0.0000000000000000001281 93.0
TLS2_k127_3323857_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 434.0
TLS2_k127_3323857_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000005403 99.0
TLS2_k127_3323857_2 Carboxypeptidase regulatory-like domain - - - 0.0000008974 54.0
TLS2_k127_3323857_3 Carboxypeptidase regulatory-like domain - - - 0.00005036 45.0
TLS2_k127_3332305_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 416.0
TLS2_k127_3332305_1 sequence-specific DNA binding K01239,K02855,K07506,K18199 - 3.2.2.1,4.2.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 306.0
TLS2_k127_3332305_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000003175 179.0
TLS2_k127_3332305_3 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000003405 168.0
TLS2_k127_3332305_4 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000000000000000005015 141.0
TLS2_k127_3332305_5 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000001156 124.0
TLS2_k127_3332305_6 DinB family - - - 0.00000000005743 69.0
TLS2_k127_3335440_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000003378 225.0
TLS2_k127_3335440_1 methyltransferase - - - 0.0000000000000000000004226 100.0
TLS2_k127_3337978_0 Carboxypeptidase regulatory-like domain - - - 0.0 1105.0
TLS2_k127_3341967_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 456.0
TLS2_k127_3341967_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006621 250.0
TLS2_k127_3341967_2 PFAM aldo keto reductase K07079 - - 0.00000000002098 75.0
TLS2_k127_334369_0 reverse transcriptase - - - 1.359e-256 796.0
TLS2_k127_334369_1 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000005583 205.0
TLS2_k127_334369_2 - - - - 0.000000000000000000000000000000000000000002082 158.0
TLS2_k127_334369_3 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000564 65.0
TLS2_k127_3350556_0 Domain of unknown function (DUF4976) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 319.0
TLS2_k127_3350556_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000003829 208.0
TLS2_k127_3350556_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000009133 184.0
TLS2_k127_3350556_3 response regulator - - - 0.0000000000000000000000003078 110.0
TLS2_k127_3351664_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000001169 124.0
TLS2_k127_3351664_1 helix_turn_helix, mercury resistance - - - 0.000000000000000000000008777 108.0
TLS2_k127_3351664_2 Protein of unknown function (DUF3040) - - - 0.000009455 53.0
TLS2_k127_3355788_0 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000005298 216.0
TLS2_k127_3355788_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000007475 200.0
TLS2_k127_3355788_2 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000000000000000000000000005252 186.0
TLS2_k127_3355788_3 PIN domain - - - 0.00002461 49.0
TLS2_k127_3363340_0 TIGRFAM type VI secretion system Vgr family protein K11904 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 494.0
TLS2_k127_3363340_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001642 271.0
TLS2_k127_3363340_2 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000001892 198.0
TLS2_k127_3363340_3 PAAR repeat-containing protein - - - 0.000000000000000000000000000000000000000003534 156.0
TLS2_k127_3363340_4 histone H2A K63-linked ubiquitination K11894 - - 0.00000000000000000000000000008493 125.0
TLS2_k127_3363340_5 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000241 72.0
TLS2_k127_3366922_0 PFAM TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 420.0
TLS2_k127_3366922_1 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000003245 143.0
TLS2_k127_3366922_2 O-methyltransferase - - - 0.0000000000000000000000000000001893 132.0
TLS2_k127_3375115_0 TonB-dependent Receptor Plug Domain - - - 0.0 1043.0
TLS2_k127_3375115_1 inositol 2-dehydrogenase activity - - - 6.546e-228 713.0
TLS2_k127_3375115_2 secondary active p-aminobenzoyl-glutamate transmembrane transporter activity K12942 - - 8.586e-222 697.0
TLS2_k127_3375115_3 Cytidylyltransferase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000002668 242.0
TLS2_k127_3375115_4 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000002008 64.0
TLS2_k127_3375213_0 Bacterial membrane protein YfhO - - - 0.00000000000000007235 95.0
TLS2_k127_3375726_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 334.0
TLS2_k127_3375726_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 344.0
TLS2_k127_3375726_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 330.0
TLS2_k127_3375726_3 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000002483 120.0
TLS2_k127_3375726_4 - - - - 0.000000000000000005158 88.0
TLS2_k127_3381913_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.412e-256 801.0
TLS2_k127_3381913_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.522e-214 671.0
TLS2_k127_3381913_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 458.0
TLS2_k127_3381913_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 452.0
TLS2_k127_3381913_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 394.0
TLS2_k127_3381913_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008731 239.0
TLS2_k127_3381913_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000007377 165.0
TLS2_k127_3381913_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000003513 81.0
TLS2_k127_3381913_8 Intracellular proteinase inhibitor - - - 0.0000327 56.0
TLS2_k127_3387393_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 402.0
TLS2_k127_3387393_1 COG0451 Nucleoside-diphosphate-sugar K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 391.0
TLS2_k127_3387393_2 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009724 261.0
TLS2_k127_3387393_3 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000002358 132.0
TLS2_k127_3387393_4 - - - - 0.000000000000003414 79.0
TLS2_k127_3387393_5 response regulator - - - 0.0000000000005983 72.0
TLS2_k127_3394158_0 - - - - 0.0000000000000000000000000000002529 128.0
TLS2_k127_3394158_1 HNH endonuclease - - - 0.00000000000007101 74.0
TLS2_k127_3394158_2 COG1403 Restriction endonuclease - - - 0.0006046 44.0
TLS2_k127_3404147_0 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 2.437e-235 739.0
TLS2_k127_3404147_1 PFAM oxidoreductase domain protein - - - 3.88e-199 635.0
TLS2_k127_3404147_2 Trehalose utilisation K15538,K21132 - 3.2.1.130,3.2.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 550.0
TLS2_k127_3404147_3 Cupin domain - - - 0.0000000000000000000000000000000000000000008119 162.0
TLS2_k127_3404147_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000001682 103.0
TLS2_k127_3415148_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 462.0
TLS2_k127_3415148_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 305.0
TLS2_k127_3415148_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000001532 149.0
TLS2_k127_341523_0 PFAM Manganese containing catalase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 401.0
TLS2_k127_341523_1 BNR repeat-like domain K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 407.0
TLS2_k127_341523_2 RnfC Barrel sandwich hybrid domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 389.0
TLS2_k127_341523_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 373.0
TLS2_k127_341523_4 BMC K04025 - - 0.00000000000000000000000000000000000000000007222 166.0
TLS2_k127_3423352_0 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 559.0
TLS2_k127_3423352_1 Domain of unknown function (DUF5060) - - - 0.0000000000000000000000000000000000000000000000000000000000000009455 228.0
TLS2_k127_3423352_2 Calcium binding - - - 0.0000000000000000000000000000000000005405 147.0
TLS2_k127_3423352_3 PFAM Resolvase - - - 0.0000000000000000001858 91.0
TLS2_k127_3423352_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000003194 89.0
TLS2_k127_3423352_5 Resolvase, N terminal domain - - - 0.0000000001393 64.0
TLS2_k127_3431009_0 Macrocin-O-methyltransferase (TylF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
TLS2_k127_3431009_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001445 244.0
TLS2_k127_3431009_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000006766 72.0
TLS2_k127_3431009_3 - - - - 0.000000008559 67.0
TLS2_k127_3431009_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000002819 55.0
TLS2_k127_3431040_0 Flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 399.0
TLS2_k127_3431040_1 MotA TolQ ExbB proton channel family - - - 0.000000000000000000000000000000000000000000001916 168.0
TLS2_k127_3431040_2 COG1734 DnaK suppressor protein K06204 - - 0.00000000000000000000000001539 113.0
TLS2_k127_3437640_0 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 7.636e-267 827.0
TLS2_k127_3437640_1 PFAM secretion protein HlyD family protein - - - 0.00000000000000000000000000000000000002779 151.0
TLS2_k127_3451217_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 462.0
TLS2_k127_3451217_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 414.0
TLS2_k127_3451217_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 302.0
TLS2_k127_3451217_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000666 193.0
TLS2_k127_3455613_0 carboxylic acid catabolic process K01684 - 4.2.1.6 1.284e-198 626.0
TLS2_k127_3455613_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 4.044e-197 626.0
TLS2_k127_3455613_10 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000524 219.0
TLS2_k127_3455613_11 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000003533 134.0
TLS2_k127_3455613_12 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000002513 129.0
TLS2_k127_3455613_13 Phage integrase family - - - 0.0000000000000000000000006071 108.0
TLS2_k127_3455613_14 mannonate dehydratase activity K01686 - 4.2.1.8 0.000000237 53.0
TLS2_k127_3455613_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 452.0
TLS2_k127_3455613_3 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 443.0
TLS2_k127_3455613_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 418.0
TLS2_k127_3455613_6 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 447.0
TLS2_k127_3455613_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 362.0
TLS2_k127_3455613_8 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001428 273.0
TLS2_k127_3455613_9 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001408 233.0
TLS2_k127_3464417_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003961 267.0
TLS2_k127_3464417_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001024 258.0
TLS2_k127_3503437_0 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 489.0
TLS2_k127_3503437_1 COG3119 Arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 445.0
TLS2_k127_3503437_2 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 405.0
TLS2_k127_3503437_3 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000001569 193.0
TLS2_k127_3503437_4 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000006012 167.0
TLS2_k127_3503437_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000009087 129.0
TLS2_k127_3503437_6 SdpI/YhfL protein family - - - 0.000000000002311 73.0
TLS2_k127_3520835_0 WD40 domain protein beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 480.0
TLS2_k127_3520835_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 457.0
TLS2_k127_3520835_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 290.0
TLS2_k127_3520835_3 Phosphoglycerate mutase K02226 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 0.00000000000000000000000000000000000000000000000000000004767 202.0
TLS2_k127_3520835_4 light absorption - - - 0.0000000000000000000000000000000000000000000000000000006253 194.0
TLS2_k127_3520835_5 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000963 128.0
TLS2_k127_3520835_6 - - - - 0.00000000000000000003138 96.0
TLS2_k127_3520835_7 YwiC-like protein - - - 0.0000000000009736 78.0
TLS2_k127_3520835_9 protein import - - - 0.0000006529 59.0
TLS2_k127_3529350_1 metal-dependent membrane protease - - - 0.0000000000000000000000000000119 131.0
TLS2_k127_3529350_2 CAAX protease self-immunity K07052 - - 0.0000000000000000000000161 108.0
TLS2_k127_3529350_4 HNH endonuclease - - - 0.0001766 51.0
TLS2_k127_3543481_0 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000007854 181.0
TLS2_k127_3543481_1 Iron dicitrate transport regulator FecR K00820 - 2.6.1.16 0.00000000000000000000000000000000000000009322 155.0
TLS2_k127_3543481_2 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 0.0000000000000000000000000000000000006665 143.0
TLS2_k127_3544136_0 transposase activity K07483,K07497 - - 0.000001657 51.0
TLS2_k127_3552834_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1648.0
TLS2_k127_3552834_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005739 235.0
TLS2_k127_3552834_2 o-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001294 215.0
TLS2_k127_35537_0 - - - - 0.0 1050.0
TLS2_k127_3557312_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 2.053e-213 695.0
TLS2_k127_3557312_1 lactoylglutathione lyase activity K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 283.0
TLS2_k127_3557312_2 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000001142 156.0
TLS2_k127_3557312_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000000004882 113.0
TLS2_k127_3557312_4 mRNA binding - - - 0.000000000000000000000000006107 113.0
TLS2_k127_3558062_0 peptidyl-tyrosine sulfation - - - 1.42e-199 631.0
TLS2_k127_3558062_1 protocatechuate 3,4-dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 314.0
TLS2_k127_35586_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1086.0
TLS2_k127_35586_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 413.0
TLS2_k127_35586_2 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 350.0
TLS2_k127_35586_3 fumarate reductase) cytochrome b subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000001258 238.0
TLS2_k127_35586_4 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000006098 196.0
TLS2_k127_35586_5 - - - - 0.000000000000000000000000000000000000000000002945 171.0
TLS2_k127_35670_0 Heat shock 70 kDa protein K04043 - - 8.498e-278 861.0
TLS2_k127_35670_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 430.0
TLS2_k127_35670_2 MerR HTH family regulatory protein K13640 - - 0.0000000000000000000000000000000000000000000002404 171.0
TLS2_k127_35670_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000007307 74.0
TLS2_k127_3582927_0 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000222 262.0
TLS2_k127_3582927_1 - - - - 0.00000000000000000005984 95.0
TLS2_k127_3582927_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000009722 66.0
TLS2_k127_3582927_4 carboxylic ester hydrolase activity - - - 0.000000003182 58.0
TLS2_k127_3587652_0 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 0.0000000000000000000000000000000000000000000001659 183.0
TLS2_k127_3587652_1 FR47-like protein K03789 - 2.3.1.128 0.00000007749 61.0
TLS2_k127_3588761_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003294 305.0
TLS2_k127_3588761_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000008212 160.0
TLS2_k127_3588761_2 Amidohydrolase - - - 0.000000000003853 78.0
TLS2_k127_3593818_0 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 535.0
TLS2_k127_3593818_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 413.0
TLS2_k127_3593818_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 348.0
TLS2_k127_3593818_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000001871 227.0
TLS2_k127_3593818_4 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000004056 139.0
TLS2_k127_3596433_0 GMC oxidoreductase - - - 1.101e-233 733.0
TLS2_k127_3596433_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 320.0
TLS2_k127_3596433_2 Involved in the tonB-independent uptake of proteins K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 312.0
TLS2_k127_3596433_3 Ham1 family K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000003884 212.0
TLS2_k127_3596433_5 ubiquitin-dependent protein catabolic process K04506,K08742,K22256 GO:0000003,GO:0000075,GO:0000151,GO:0000209,GO:0000278,GO:0000280,GO:0000902,GO:0000904,GO:0001654,GO:0001745,GO:0001751,GO:0001752,GO:0001754,GO:0002065,GO:0002067,GO:0003674,GO:0003712,GO:0003714,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005768,GO:0005769,GO:0005829,GO:0005886,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006915,GO:0006928,GO:0006935,GO:0006996,GO:0007049,GO:0007093,GO:0007127,GO:0007140,GO:0007141,GO:0007154,GO:0007165,GO:0007264,GO:0007275,GO:0007276,GO:0007283,GO:0007346,GO:0007399,GO:0007409,GO:0007411,GO:0007423,GO:0007465,GO:0008022,GO:0008150,GO:0008152,GO:0008219,GO:0008270,GO:0009056,GO:0009057,GO:0009605,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010466,GO:0010498,GO:0010556,GO:0010558,GO:0010605,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0010821,GO:0010823,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0016020,GO:0016043,GO:0016567,GO:0016579,GO:0016740,GO:0019005,GO:0019219,GO:0019222,GO:0019538,GO:0019787,GO:0019899,GO:0019904,GO:0019941,GO:0019953,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022603,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030162,GO:0030163,GO:0030178,GO:0030182,GO:0030855,GO:0030877,GO:0031175,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031396,GO:0031399,GO:0031410,GO:0031461,GO:0031624,GO:0031647,GO:0031648,GO:0031974,GO:0031981,GO:0031982,GO:0032268,GO:0032269,GO:0032386,GO:0032387,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033043,GO:0033157,GO:0035556,GO:0035883,GO:0036211,GO:0036477,GO:0040008,GO:0040011,GO:0040014,GO:0042221,GO:0042330,GO:0042706,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043086,GO:0043154,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043281,GO:0043412,GO:0043621,GO:0043632,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044297,GO:0044390,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045165,GO:0045466,GO:0045595,GO:0045664,GO:0045676,GO:0045786,GO:0045861,GO:0045930,GO:0045934,GO:0046530,GO:0046532,GO:0046552,GO:0046872,GO:0046914,GO:0046983,GO:0048232,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048592,GO:0048609,GO:0048638,GO:0048663,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048749,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050767,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051223,GO:0051224,GO:0051239,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051321,GO:0051336,GO:0051346,GO:0051402,GO:0051603,GO:0051704,GO:0051716,GO:0051726,GO:0051960,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060548,GO:0060828,GO:0061564,GO:0061630,GO:0061659,GO:0061982,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070646,GO:0070647,GO:0070997,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090087,GO:0090090,GO:0090317,GO:0090596,GO:0097458,GO:0097485,GO:0097708,GO:0097718,GO:0120025,GO:0120036,GO:0120039,GO:0140013,GO:0140096,GO:0140110,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1902531,GO:1902533,GO:1902679,GO:1903046,GO:1903047,GO:1903214,GO:1903215,GO:1903320,GO:1903506,GO:1903507,GO:1903533,GO:1903747,GO:1903748,GO:1903827,GO:1903828,GO:1904950,GO:1990234,GO:2000026,GO:2000027,GO:2000116,GO:2000117,GO:2001141,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001242,GO:2001244 2.3.2.27 0.000000000003718 72.0
TLS2_k127_3607918_0 PFAM Cytochrome c assembly protein K02198 - - 2.911e-286 893.0
TLS2_k127_3607918_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000001745 168.0
TLS2_k127_3607918_2 - - - - 0.00000000000000000000000000000000000000203 151.0
TLS2_k127_3607918_3 - - - - 0.000000000000000000000000000000000005205 147.0
TLS2_k127_3607918_4 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.000000000000000000000000000000003391 137.0
TLS2_k127_3607918_5 Methionine biosynthesis protein MetW - - - 0.000000000006945 70.0
TLS2_k127_3619848_0 MacB-like periplasmic core domain - - - 5.602e-206 670.0
TLS2_k127_3619848_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000005078 129.0
TLS2_k127_3625728_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 498.0
TLS2_k127_3625728_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 478.0
TLS2_k127_3625728_2 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 456.0
TLS2_k127_3625728_3 DNA integration - - - 0.0000000000000000000000000000000001305 138.0
TLS2_k127_3625728_4 Phage integrase family - - - 0.00000000000003316 75.0
TLS2_k127_3635305_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 554.0
TLS2_k127_3635305_1 Transposase domain (DUF772) K07487 - - 0.0000000000000000000000000001425 117.0
TLS2_k127_3635305_2 COG3316 Transposase and inactivated derivatives - - - 0.00000000000261 68.0
TLS2_k127_3635305_3 PFAM Sodium sulfate symporter transmembrane region K14445 - - 0.000000000005186 75.0
TLS2_k127_3650834_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 536.0
TLS2_k127_3650834_1 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
TLS2_k127_3650834_2 - - - - 0.0000000000000000000000000000000000000000008215 171.0
TLS2_k127_3650834_3 Xylose isomerase-like TIM barrel K22233 - - 0.00000000000000000000000000000000000000002124 165.0
TLS2_k127_3650834_4 Provides the (R)-glutamate required for cell wall biosynthesis - - - 0.00000000000000000000000000000003841 134.0
TLS2_k127_3650834_5 Outer membrane efflux protein K18139 - - 0.0001018 47.0
TLS2_k127_3664144_0 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002022 260.0
TLS2_k127_3664144_1 Integrase - - - 0.0000000005936 68.0
TLS2_k127_3666517_0 - - - - 0.0000000000000000000000000000000000000000000000000000007752 208.0
TLS2_k127_3666517_1 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000008948 145.0
TLS2_k127_3666517_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000001345 91.0
TLS2_k127_366945_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 435.0
TLS2_k127_366945_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 402.0
TLS2_k127_366945_2 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 389.0
TLS2_k127_366945_3 translation release factor activity - - - 0.0000000000000000005937 94.0
TLS2_k127_366945_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000001421 87.0
TLS2_k127_3670769_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 506.0
TLS2_k127_3670769_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 491.0
TLS2_k127_3670769_2 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 396.0
TLS2_k127_3670769_3 glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 332.0
TLS2_k127_3670769_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001957 240.0
TLS2_k127_3670769_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000002477 197.0
TLS2_k127_3670769_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000494 214.0
TLS2_k127_3670769_7 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000001252 191.0
TLS2_k127_3671710_0 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 342.0
TLS2_k127_3671710_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000002236 198.0
TLS2_k127_3671710_2 Sulfatase - - - 0.00000000000000000000000000000005927 130.0
TLS2_k127_3671710_3 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000001961 103.0
TLS2_k127_3671710_4 Putative zinc-finger - - - 0.000001175 55.0
TLS2_k127_3681809_0 TIGRFAM amino acid adenylation domain - - - 0.0 1937.0
TLS2_k127_3681809_1 Penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 1.358e-215 696.0
TLS2_k127_3681809_2 Amino acid adenylation domain - - - 3.159e-198 636.0
TLS2_k127_3684655_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 383.0
TLS2_k127_3684655_1 Encoded by - - - 0.00000000000008567 83.0
TLS2_k127_3693655_0 Transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 502.0
TLS2_k127_3695978_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 494.0
TLS2_k127_3695978_1 - - - - 0.0004594 51.0
TLS2_k127_3708398_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.784e-207 662.0
TLS2_k127_3708398_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 323.0
TLS2_k127_3708398_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000004711 200.0
TLS2_k127_3708398_3 PFAM sulfatase - - - 0.000000000000000000000005895 104.0
TLS2_k127_3710428_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 3.065e-299 930.0
TLS2_k127_3710428_1 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 511.0
TLS2_k127_3710428_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000001028 187.0
TLS2_k127_371248_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 392.0
TLS2_k127_371248_1 Pfam:DUF2276 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000103 272.0
TLS2_k127_371248_2 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008731 229.0
TLS2_k127_371248_3 cellulose binding - - - 0.000000000000000000000000004065 117.0
TLS2_k127_3716850_0 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 462.0
TLS2_k127_3716850_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 367.0
TLS2_k127_3716850_2 - - - - 0.00000000000000000000000000000000000000000000000000002855 198.0
TLS2_k127_3720296_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000005791 194.0
TLS2_k127_3735553_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.014e-223 696.0
TLS2_k127_3735553_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000001298 162.0
TLS2_k127_374098_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 476.0
TLS2_k127_374098_1 BNR repeat-like domain - - - 0.000000000000000000000000000000000000009498 156.0
TLS2_k127_374098_2 BNR repeat-like domain - - - 0.0000000000000000045 96.0
TLS2_k127_3742735_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 445.0
TLS2_k127_3742735_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 366.0
TLS2_k127_3742735_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000002525 227.0
TLS2_k127_3742735_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000001298 119.0
TLS2_k127_3746804_0 penicillin amidase K01434 - 3.5.1.11 2.61e-205 664.0
TLS2_k127_3746804_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000002545 162.0
TLS2_k127_3746804_2 cytochrome C peroxidase - - - 0.00000000000000000000000000000000001942 140.0
TLS2_k127_3746804_3 Protein of unknown function (DUF3574) - - - 0.000000000000000000000000000021 123.0
TLS2_k127_3746804_4 PFAM Peptidase M20 - - - 0.000000000000000000002821 97.0
TLS2_k127_3753735_0 GMC oxidoreductase - - - 7.974e-261 814.0
TLS2_k127_3753735_1 Phosphomethylpyrimidine kinase K00882 - 2.7.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 377.0
TLS2_k127_3753735_2 Conserved carboxylase domain K03416 - 2.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 299.0
TLS2_k127_3753735_3 - - - - 0.000000000000000000000000000000000000000000000000000000000004391 223.0
TLS2_k127_3753735_5 - - - - 0.000000000000000000000000000000001025 142.0
TLS2_k127_3763300_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 575.0
TLS2_k127_3763300_1 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 424.0
TLS2_k127_3763300_2 C-terminal of Glycosyl hydrolases family 43 K06113 - 3.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 404.0
TLS2_k127_3763300_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 356.0
TLS2_k127_3763300_4 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 349.0
TLS2_k127_3763300_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 308.0
TLS2_k127_3763300_6 Peptidase family S51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001628 262.0
TLS2_k127_3763300_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009281 236.0
TLS2_k127_3763300_8 - - - - 0.00000000000000000000004123 100.0
TLS2_k127_3764778_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.335e-259 805.0
TLS2_k127_3764778_1 glutamate:sodium symporter activity K03312 GO:0003333,GO:0003674,GO:0005215,GO:0005283,GO:0005310,GO:0005342,GO:0005343,GO:0005416,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006820,GO:0006835,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015081,GO:0015171,GO:0015291,GO:0015293,GO:0015294,GO:0015318,GO:0015370,GO:0015501,GO:0015672,GO:0015711,GO:0015849,GO:0016020,GO:0017153,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0044464,GO:0046873,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 366.0
TLS2_k127_3764778_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 319.0
TLS2_k127_3764778_3 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001345 227.0
TLS2_k127_3764778_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000008214 202.0
TLS2_k127_3764778_5 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000003291 179.0
TLS2_k127_3776004_0 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 586.0
TLS2_k127_3776004_1 Protein of unknown function (DUF1587) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001436 261.0
TLS2_k127_3776004_2 - - - - 0.000000000000000003471 87.0
TLS2_k127_3779930_0 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 290.0
TLS2_k127_3779930_1 photoreceptor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002325 282.0
TLS2_k127_3779930_2 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004539 238.0
TLS2_k127_3779930_3 candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238 K18197 - 4.2.2.23 0.00002294 51.0
TLS2_k127_3780161_0 cluster binding protein K18929 - - 2.682e-212 668.0
TLS2_k127_3780161_1 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000006122 201.0
TLS2_k127_3780161_2 Pfam:DUF162 K00782 - - 0.0000168 55.0
TLS2_k127_3783551_0 arylsulfatase activity - - - 1.544e-194 614.0
TLS2_k127_3783551_1 Cytochrome c - - - 0.000000000000000000000000000006989 121.0
TLS2_k127_3783778_0 Carboxypeptidase regulatory-like domain - - - 0.0 1303.0
TLS2_k127_3783778_1 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 2.718e-196 626.0
TLS2_k127_3783778_2 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 6.139e-196 625.0
TLS2_k127_3783778_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 297.0
TLS2_k127_3783778_4 LOR/SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000007811 211.0
TLS2_k127_3783778_5 Domain of unknown function (DUF4962) K19051 GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510 4.2.2.7,4.2.2.8 0.0005553 49.0
TLS2_k127_3784122_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1358.0
TLS2_k127_3784122_1 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 325.0
TLS2_k127_3784122_2 spheroidene biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001094 276.0
TLS2_k127_3791503_0 TonB-dependent receptor - - - 1.161e-291 932.0
TLS2_k127_3791503_1 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 535.0
TLS2_k127_3791503_2 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 446.0
TLS2_k127_3791503_3 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 398.0
TLS2_k127_3791503_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 373.0
TLS2_k127_3791503_5 IclR helix-turn-helix domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 301.0
TLS2_k127_3791503_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000002066 238.0
TLS2_k127_3791503_7 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000615 142.0
TLS2_k127_3795149_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 370.0
TLS2_k127_3795149_1 Protein phosphatase 2C K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002585 254.0
TLS2_k127_3795149_2 TIGRFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000007091 238.0
TLS2_k127_3795149_3 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002943 238.0
TLS2_k127_3795149_4 Conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000000000000000158 226.0
TLS2_k127_3795149_5 - - - - 0.0000000000000000000000000000000000004821 148.0
TLS2_k127_3795149_6 - - - - 0.00000000000000000000000000000005323 128.0
TLS2_k127_3795149_7 TIGRFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000001589 94.0
TLS2_k127_3795149_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000003571 81.0
TLS2_k127_3795149_9 Carboxypeptidase regulatory-like domain - - - 0.00000000000004111 75.0
TLS2_k127_3806248_0 Protein of unknown function (DUF1595) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 496.0
TLS2_k127_3806248_1 Protein of unknown function (DUF1552) - - - 0.0000000000000000000002743 99.0
TLS2_k127_3814218_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 307.0
TLS2_k127_3814218_1 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004821 277.0
TLS2_k127_3818589_0 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 375.0
TLS2_k127_3818589_1 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 353.0
TLS2_k127_3818589_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000002313 229.0
TLS2_k127_3818589_3 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.0003379 51.0
TLS2_k127_3819832_0 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 492.0
TLS2_k127_3819832_1 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 434.0
TLS2_k127_3819832_10 Carbon-nitrogen hydrolase K03820 - - 0.000002682 61.0
TLS2_k127_3819832_2 COG0346 Lactoylglutathione lyase and related lyases K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 395.0
TLS2_k127_3819832_3 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 341.0
TLS2_k127_3819832_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000316 269.0
TLS2_k127_3819832_5 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000004065 242.0
TLS2_k127_3819832_6 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000613 199.0
TLS2_k127_3819832_7 - - - - 0.0000000000000000000000000000000000000000000000007115 181.0
TLS2_k127_3819832_8 - - - - 0.00000000000000000000000000000000005186 144.0
TLS2_k127_3819832_9 Helix-turn-helix domain - - - 0.00000000000000000000000002117 114.0
TLS2_k127_3821756_0 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000006262 233.0
TLS2_k127_3821756_1 lysozyme - - - 0.0000000000000000000000000000000000000000000000000008476 197.0
TLS2_k127_3821756_2 CHAT domain - - - 0.0000000000000000000000000000000000001506 162.0
TLS2_k127_3821756_3 - - - - 0.000000000000000000000000000000000006326 154.0
TLS2_k127_3830535_0 PFAM oxidoreductase domain protein - - - 4.767e-206 643.0
TLS2_k127_3830535_1 - - - - 0.0000000000000000000000000000000000000000000004406 176.0
TLS2_k127_3831548_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 612.0
TLS2_k127_3831548_1 spheroidene biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 391.0
TLS2_k127_3831548_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001578 227.0
TLS2_k127_3831548_3 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.00000000000000000341 88.0
TLS2_k127_3832899_0 Glutamate-ammonia ligase adenylyltransferase K00982 - 2.7.7.42,2.7.7.89 4.772e-315 989.0
TLS2_k127_3832899_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00004061 51.0
TLS2_k127_3834830_0 Beta-galactosidase - - - 4.816e-264 844.0
TLS2_k127_3834830_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 429.0
TLS2_k127_3834830_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 357.0
TLS2_k127_3834830_3 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
TLS2_k127_3834830_4 Di-glucose binding within endoplasmic reticulum - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001526 278.0
TLS2_k127_3834830_5 CAAX amino terminal protease family protein K07052 - - 0.0000002019 62.0
TLS2_k127_3838148_0 Hypothetical glycosyl hydrolase 6 - - - 0.0 1030.0
TLS2_k127_3838148_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 585.0
TLS2_k127_3838148_10 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000003968 208.0
TLS2_k127_3838148_11 regulation of DNA repair K03565 - - 0.00000000000000000000000000000001251 139.0
TLS2_k127_3838148_13 YtxH-like protein - - - 0.0000000000000000000001597 105.0
TLS2_k127_3838148_14 Malate/L-lactate dehydrogenase - - - 0.000000001542 61.0
TLS2_k127_3838148_15 PFAM TonB-dependent Receptor Plug - - - 0.00003201 52.0
TLS2_k127_3838148_16 - - - - 0.0005528 49.0
TLS2_k127_3838148_2 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 539.0
TLS2_k127_3838148_3 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 443.0
TLS2_k127_3838148_4 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 434.0
TLS2_k127_3838148_5 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 342.0
TLS2_k127_3838148_6 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 309.0
TLS2_k127_3838148_7 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 293.0
TLS2_k127_3838148_8 PFAM Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002581 276.0
TLS2_k127_3838148_9 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000004793 212.0
TLS2_k127_3841295_0 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000004548 229.0
TLS2_k127_3841295_1 iron dependent repressor - - - 0.0000000000000000000000000000000000000000000002187 182.0
TLS2_k127_3841295_2 Integrase - - - 0.00000000000000000000001926 104.0
TLS2_k127_3843248_0 Fumarylacetoacetase K01555 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 539.0
TLS2_k127_3843248_1 Acetyl-coenzyme A synthetase N-terminus - - - 0.00000000000000000000000000000000000000001054 156.0
TLS2_k127_3843248_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000991 118.0
TLS2_k127_3852787_0 Penicillin amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 439.0
TLS2_k127_3852787_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000003733 226.0
TLS2_k127_3852787_2 conserved protein, contains double-stranded beta-helix domain - - - 0.00005243 51.0
TLS2_k127_3853628_0 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 359.0
TLS2_k127_3853628_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 331.0
TLS2_k127_3853628_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000002311 228.0
TLS2_k127_3853628_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000006089 154.0
TLS2_k127_3853628_4 Putative zinc-finger - - - 0.000000000000000007814 93.0
TLS2_k127_3853628_5 - - - - 0.000000000000001973 86.0
TLS2_k127_3860954_0 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 497.0
TLS2_k127_3860954_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 306.0
TLS2_k127_3860954_2 response regulator - - - 0.0000000000000000000000000000000000000000004439 162.0
TLS2_k127_3871194_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 416.0
TLS2_k127_3871194_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 338.0
TLS2_k127_3878037_0 siderophore transport K02014 - - 5.455e-205 664.0
TLS2_k127_3878037_1 beta-galactosidase activity K01190,K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 451.0
TLS2_k127_3881451_0 recombinase activity - - - 3.644e-274 859.0
TLS2_k127_3881451_1 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000104 147.0
TLS2_k127_3881451_3 Integrase core domain - - - 0.0000005619 53.0
TLS2_k127_3883688_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.258e-313 966.0
TLS2_k127_3883688_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 557.0
TLS2_k127_3883688_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 516.0
TLS2_k127_3885394_0 PFAM Resolvase - - - 0.000000000000000000000000000000000000000000000000003263 188.0
TLS2_k127_3885394_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000006222 175.0
TLS2_k127_3885394_2 Calcium binding - - - 0.000000000000000000000000000000000000005229 150.0
TLS2_k127_3885394_3 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.000000000005518 72.0
TLS2_k127_3885394_4 NB-ARC domain - - - 0.0000000003717 71.0
TLS2_k127_3885469_0 flagellar basal-body rod protein FlgG K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 446.0
TLS2_k127_3885469_1 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 362.0
TLS2_k127_3885469_10 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation - - - 0.000006736 51.0
TLS2_k127_3885469_2 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 334.0
TLS2_k127_3885469_3 FlhB HrpN YscU SpaS Family K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 305.0
TLS2_k127_3885469_4 basal body rod protein K02391,K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000003117 240.0
TLS2_k127_3885469_5 Bacterial export proteins, family 1 K02421 - - 0.000000000000000000000000000000000000000000000000000000000000009193 224.0
TLS2_k127_3885469_6 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000001593 203.0
TLS2_k127_3885469_7 flagellar K02418 - - 0.000000000005434 70.0
TLS2_k127_3885469_8 Required for flagellar hook formation. May act as a scaffolding protein K02389 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000009349 72.0
TLS2_k127_3885469_9 Bacterial export proteins, family 3 K02420 - - 0.00000000004075 66.0
TLS2_k127_3887374_0 unidirectional conjugation K03205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 401.0
TLS2_k127_3887374_1 Domain of unknown function (DUF1738) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 391.0
TLS2_k127_3893739_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 484.0
TLS2_k127_3893739_1 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 325.0
TLS2_k127_3893739_2 Sucrase/ferredoxin-like - - - 0.000000000000000000000000000000000000009505 154.0
TLS2_k127_3895912_0 metallopeptidase activity K01637 - 4.1.3.1 0.00000000000000000000000000001545 139.0
TLS2_k127_3895912_1 - - - - 0.000000000001156 67.0
TLS2_k127_3895912_2 - - - - 0.00000000009707 66.0
TLS2_k127_3895912_3 Ami_2 - - - 0.00000001627 69.0
TLS2_k127_3897643_0 Polysulphide reductase, NrfD K00185 - - 7.989e-220 693.0
TLS2_k127_3897643_1 PFAM 4Fe-4S K00184,K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 422.0
TLS2_k127_3897643_2 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006274 244.0
TLS2_k127_3897643_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0009174 44.0
TLS2_k127_3901791_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000002003 214.0
TLS2_k127_3901791_1 pathogenesis K01460 - 3.5.1.78,6.3.1.8 0.000000000000000000000000000000000000000000001293 181.0
TLS2_k127_390269_0 Carboxypeptidase regulatory-like domain - - - 0.0 1192.0
TLS2_k127_390269_1 SNF2 Helicase protein - - - 1.144e-271 841.0
TLS2_k127_390269_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01639,K01714 - 4.1.3.3,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 330.0
TLS2_k127_390269_11 BNR repeat-like domain K01186 - 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 276.0
TLS2_k127_390269_12 Pfam:Methyltransf_6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004714 246.0
TLS2_k127_390269_13 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000006051 236.0
TLS2_k127_390269_14 COGs COG0591 Na proline symporter K03307 - - 0.0000000000000000000000000000000000000000000000000000006555 206.0
TLS2_k127_390269_15 Demethylmenaquinone methyltransferase - - - 0.0000000000000000000000000000000000000000000000000009515 192.0
TLS2_k127_390269_16 FCD - - - 0.0000000000000000000000000000000000000000299 163.0
TLS2_k127_390269_17 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000002325 164.0
TLS2_k127_390269_18 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000009514 145.0
TLS2_k127_390269_19 Aldolase/RraA - - - 0.000000000000000000000000000000002757 137.0
TLS2_k127_390269_2 FAD dependent oxidoreductase - - - 1.684e-210 666.0
TLS2_k127_390269_20 Transcriptional regulator, GntR family - - - 0.000000000000000000000001338 112.0
TLS2_k127_390269_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 593.0
TLS2_k127_390269_4 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 554.0
TLS2_k127_390269_5 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 528.0
TLS2_k127_390269_6 SNF2 Helicase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 504.0
TLS2_k127_390269_7 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 441.0
TLS2_k127_390269_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 416.0
TLS2_k127_390269_9 SWIM zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 361.0
TLS2_k127_390271_0 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008368 233.0
TLS2_k127_390271_1 -O-antigen K02847 - - 0.0000000000000000000000000000000000000000000002532 188.0
TLS2_k127_390271_2 Glycosyl hydrolase family 1 - - - 0.000000000000008482 87.0
TLS2_k127_3905937_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 469.0
TLS2_k127_3905937_1 guanyl-nucleotide exchange factor activity K01191,K01406,K20276 - 3.2.1.24,3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000001841 291.0
TLS2_k127_3905937_2 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000003435 249.0
TLS2_k127_3905937_3 inositol 2-dehydrogenase activity K19181 - 1.1.1.292 0.0000000000000000000000000000000000000000000000000003064 198.0
TLS2_k127_3905937_4 Fibronectin type 3 domain-containing protein K06882 - - 0.0009704 53.0
TLS2_k127_3908264_0 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 347.0
TLS2_k127_3908264_1 DNA restriction-modification system - - - 0.00000000000000000000000000000000000000000000000000000000000003843 220.0
TLS2_k127_3908566_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
TLS2_k127_3908566_1 Plasmid encoded RepA protein - - - 0.00000000000000000000000000000000000000000000000005228 182.0
TLS2_k127_3908566_2 Protein kinase domain - - - 0.00000000000000001609 96.0
TLS2_k127_3908851_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 602.0
TLS2_k127_3908851_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 522.0
TLS2_k127_3908851_2 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 318.0
TLS2_k127_3908851_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008939 285.0
TLS2_k127_3908851_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000001651 223.0
TLS2_k127_3908851_5 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000006267 169.0
TLS2_k127_3908851_6 Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria K02337,K14162 - 2.7.7.7 0.0000000000000000634 82.0
TLS2_k127_3908851_7 May be the GTPase, regulating ATP sulfurylase activity K00955 - 2.7.1.25,2.7.7.4 0.00000008098 59.0
TLS2_k127_3908851_8 Transposase (IS116 IS110 IS902 family) - - - 0.000001856 54.0
TLS2_k127_3917373_0 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 1.345e-283 888.0
TLS2_k127_3917373_1 6-phospho-beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 478.0
TLS2_k127_3917373_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 443.0
TLS2_k127_3917373_3 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 426.0
TLS2_k127_3917373_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 301.0
TLS2_k127_3917373_5 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 264.0
TLS2_k127_3917373_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000001242 235.0
TLS2_k127_3917373_7 phosphoenolpyruvate carboxylase activity - - - 0.00000000009083 64.0
TLS2_k127_3918262_0 Belongs to the helicase family. UvrD subfamily - - - 1.52e-251 800.0
TLS2_k127_3918262_1 Sugar (and other) transporter - - - 1.971e-201 635.0
TLS2_k127_3918262_2 methyltransferase activity K04786,K12240,K13613,K15677 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 456.0
TLS2_k127_3918262_4 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 326.0
TLS2_k127_3918262_5 teichoic acid transport K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006006 278.0
TLS2_k127_3918262_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000001029 215.0
TLS2_k127_3920369_0 COG3668 Plasmid stabilization system protein K19092 - - 0.0000000000000000000000000002478 117.0
TLS2_k127_3920369_2 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH - - - 0.000000000000008303 78.0
TLS2_k127_3920369_3 toxic component of a K07065 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000239 75.0
TLS2_k127_3920664_0 ABC transporter transmembrane region K06147,K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 421.0
TLS2_k127_3920664_1 protein conserved in cyanobacteria - - - 0.00000000000000005488 84.0
TLS2_k127_3921964_0 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.0 1574.0
TLS2_k127_3921964_1 Carboxypeptidase regulatory-like domain - - - 0.0 1273.0
TLS2_k127_3921964_10 - - - - 0.000000000000000000000000000000666 126.0
TLS2_k127_3921964_11 Cytochrome c - - - 0.0000000000000000000000006011 113.0
TLS2_k127_3921964_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0002295 48.0
TLS2_k127_3921964_2 PFAM Amidase K01457,K01941 - 3.5.1.54,6.3.4.6 5.066e-231 730.0
TLS2_k127_3921964_3 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 548.0
TLS2_k127_3921964_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 441.0
TLS2_k127_3921964_5 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 353.0
TLS2_k127_3921964_6 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 344.0
TLS2_k127_3921964_7 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002786 232.0
TLS2_k127_3921964_8 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000004624 225.0
TLS2_k127_3921964_9 DoxX - - - 0.00000000000000000000000000000000000000000000000000002941 190.0
TLS2_k127_3925465_0 eRF1 domain 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 351.0
TLS2_k127_3925465_1 transposition K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002891 270.0
TLS2_k127_3925465_2 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000754 119.0
TLS2_k127_3925465_3 Helix-turn-helix domain - - - 0.00000000000000000009264 93.0
TLS2_k127_3925465_4 Integrase - - - 0.0000000006333 65.0
TLS2_k127_3943730_0 Carboxypeptidase regulatory-like domain - - - 1.638e-201 666.0
TLS2_k127_3943730_1 efflux transmembrane transporter activity - - - 0.00000000001114 69.0
TLS2_k127_3945354_0 TonB-dependent receptor - - - 7.929e-241 771.0
TLS2_k127_3945354_1 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 299.0
TLS2_k127_3945354_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000992 186.0
TLS2_k127_3945354_3 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.000000000000000000000000000000000000000268 159.0
TLS2_k127_3946779_0 PFAM SAF domain K02279 - - 0.000000000000000000000000000000000001405 143.0
TLS2_k127_3946779_1 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000007018 127.0
TLS2_k127_3946779_2 TadE-like protein - - - 0.00000000000000000001586 98.0
TLS2_k127_3946779_3 PFAM TadE family protein K02282 - - 0.0000000000000000002128 93.0
TLS2_k127_3946779_4 FtsK/SpoIIIE family K03466 - - 0.0000003037 53.0
TLS2_k127_3946779_5 Flp/Fap pilin component K02651 - - 0.0000924 48.0
TLS2_k127_3953641_0 heme binding - - - 0.000000000000000000000000000001161 137.0
TLS2_k127_3953641_1 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000004881 119.0
TLS2_k127_3959754_0 protein secretion by the type IV secretion system K03201,K07344,K12052,K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 504.0
TLS2_k127_3959754_1 conjugation K20266 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 322.0
TLS2_k127_3959754_2 type IV secretory pathway VirB4 K03199 - - 0.000000000000000000000000000000000002644 139.0
TLS2_k127_3960212_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 8.132e-293 908.0
TLS2_k127_3960212_1 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 482.0
TLS2_k127_3962472_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 430.0
TLS2_k127_3962472_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 385.0
TLS2_k127_3962472_2 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 306.0
TLS2_k127_3962472_3 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000004551 204.0
TLS2_k127_3962472_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000004044 138.0
TLS2_k127_3962472_5 TIGRFAM glycosyltransferase, MGT family - - - 0.000000001412 61.0
TLS2_k127_3962472_6 PFAM Methyltransferase type - - - 0.00001569 47.0
TLS2_k127_3967535_0 Oxidoreductase - - - 1.101e-214 687.0
TLS2_k127_3967535_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 583.0
TLS2_k127_3967535_10 PFAM Glycosyl transferase family 4 K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 414.0
TLS2_k127_3967535_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 360.0
TLS2_k127_3967535_12 Male sterility protein K00091,K01784 - 1.1.1.219,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 329.0
TLS2_k127_3967535_13 Cytidylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 314.0
TLS2_k127_3967535_14 Pfam Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 305.0
TLS2_k127_3967535_15 inositol 2-dehydrogenase activity K19181 - 1.1.1.292 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000527 288.0
TLS2_k127_3967535_16 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006571 281.0
TLS2_k127_3967535_17 Formyl transferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001172 270.0
TLS2_k127_3967535_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007939 251.0
TLS2_k127_3967535_19 Protein of unknown function (DUF354) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003113 243.0
TLS2_k127_3967535_2 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 586.0
TLS2_k127_3967535_20 transferase activity, transferring hexosyl groups K15897 - 3.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000001966 238.0
TLS2_k127_3967535_21 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000001064 227.0
TLS2_k127_3967535_22 ABC transporter transmembrane region K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000004651 236.0
TLS2_k127_3967535_23 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000004943 222.0
TLS2_k127_3967535_24 Involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000004594 184.0
TLS2_k127_3967535_25 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000002571 174.0
TLS2_k127_3967535_26 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000005635 167.0
TLS2_k127_3967535_27 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001003 161.0
TLS2_k127_3967535_28 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000006655 157.0
TLS2_k127_3967535_29 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000001636 127.0
TLS2_k127_3967535_3 ATPase of the PP-loop superfamily implicated in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 524.0
TLS2_k127_3967535_30 Methyltransferase domain - - - 0.000000000000000000000000000001825 130.0
TLS2_k127_3967535_31 extracellular polysaccharide biosynthetic process K16554,K21473 - - 0.000000000000000000000000002031 125.0
TLS2_k127_3967535_32 capsule polysaccharide - - - 0.00000000000000000001613 106.0
TLS2_k127_3967535_33 Methyltransferase domain K18827 - 2.1.1.294,2.7.1.181 0.00000000003427 72.0
TLS2_k127_3967535_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 518.0
TLS2_k127_3967535_5 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 509.0
TLS2_k127_3967535_6 TIGRFAM pseudaminic acid synthase K01654,K15898 - 2.5.1.56,2.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 490.0
TLS2_k127_3967535_7 PFAM Polysaccharide biosynthesis protein K15894 - 4.2.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 460.0
TLS2_k127_3967535_8 Polysaccharide biosynthesis protein CapD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 444.0
TLS2_k127_3967535_9 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 428.0
TLS2_k127_3968036_0 unidirectional conjugation K03205 - - 3.365e-293 913.0
TLS2_k127_3968036_1 Type IV secretory pathway protease TraF - - - 0.0000000000000000000000000000000000000000009308 163.0
TLS2_k127_3968036_2 single-stranded DNA binding K03111 - - 0.00000000000000000000000000000000000000006967 155.0
TLS2_k127_3968036_3 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000005528 159.0
TLS2_k127_3968036_4 hmm pf01609 - - - 0.00000000000000000000000000000000001714 143.0
TLS2_k127_3968036_5 Domain of unknown function (DUF1738) - - - 0.000000000000000001592 90.0
TLS2_k127_3968036_6 - - - - 0.0000003397 57.0
TLS2_k127_3973658_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 327.0
TLS2_k127_3973658_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000003988 179.0
TLS2_k127_3973658_2 ECF sigma factor - - - 0.00000000000000000000000000000000137 137.0
TLS2_k127_3975785_0 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 400.0
TLS2_k127_3975785_1 Ankyrin repeats (many copies) K06015,K06867,K06886 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000009242 260.0
TLS2_k127_3975785_2 Cell division protein ZapA K09888 - - 0.0000000000000000002331 90.0
TLS2_k127_3975785_3 Alginate export - - - 0.000000000002548 76.0
TLS2_k127_3978929_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 530.0
TLS2_k127_3978929_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 497.0
TLS2_k127_3978929_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000001987 213.0
TLS2_k127_3978929_3 cyclopropane-fatty-acyl-phospholipid synthase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000001002 107.0
TLS2_k127_3992610_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 619.0
TLS2_k127_3992610_1 PFAM Transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 419.0
TLS2_k127_3993959_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000001601 229.0
TLS2_k127_3995534_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 429.0
TLS2_k127_3995534_1 recombinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 390.0
TLS2_k127_3995534_2 DNA invertase Pin - - - 0.00000000000000000000000000115 115.0
TLS2_k127_4002849_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 520.0
TLS2_k127_4002849_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 413.0
TLS2_k127_4002849_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 324.0
TLS2_k127_4009562_0 Group II intron, maturase-specific domain K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 428.0
TLS2_k127_4009562_1 COG3328 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000005394 205.0
TLS2_k127_4010381_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005799 275.0
TLS2_k127_4010381_1 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
TLS2_k127_402733_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 355.0
TLS2_k127_402733_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000002685 166.0
TLS2_k127_402733_2 InterPro IPR007367 - - - 0.0000000000000000000000000000000000000002271 156.0
TLS2_k127_402733_3 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000000000000000003817 157.0
TLS2_k127_402733_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000001036 141.0
TLS2_k127_402733_5 - - - - 0.0000000000000000000000001104 109.0
TLS2_k127_402733_6 energy transducer activity - - - 0.0000000000000000000005919 110.0
TLS2_k127_4038842_0 Methyltransferase domain - - - 2.49e-217 683.0
TLS2_k127_4038842_1 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000008053 169.0
TLS2_k127_4038991_0 Belongs to the glycosyl hydrolase 2 family - - - 2.148e-285 899.0
TLS2_k127_4038991_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 558.0
TLS2_k127_4038991_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000001138 114.0
TLS2_k127_4038991_11 Methyltransferase domain - - - 0.000000000000000000000003114 114.0
TLS2_k127_4038991_12 Protein of unknown function (DUF2442) - - - 0.00000000003049 67.0
TLS2_k127_4038991_13 Domain of unknown function (DUF4160) - - - 0.00000000003669 65.0
TLS2_k127_4038991_14 Ankyrin repeat - - - 0.00002597 51.0
TLS2_k127_4038991_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 477.0
TLS2_k127_4038991_3 DNA (cytosine-5-)-methyltransferase activity K00558 - 2.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 454.0
TLS2_k127_4038991_4 PFAM sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 440.0
TLS2_k127_4038991_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 422.0
TLS2_k127_4038991_6 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 373.0
TLS2_k127_4038991_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 273.0
TLS2_k127_4038991_9 May nick specific sequences that contain T G mispairs resulting from m5C-deamination K07458 - - 0.0000000000000000000000000000000001264 139.0
TLS2_k127_4048501_0 2-keto-3-deoxy-L-rhamnonate aldolase activity K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 303.0
TLS2_k127_4048501_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 293.0
TLS2_k127_4048501_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000002549 93.0
TLS2_k127_4048501_4 KR domain - - - 0.00000009685 55.0
TLS2_k127_4054784_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 537.0
TLS2_k127_4054784_1 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 394.0
TLS2_k127_4054784_2 Protein of unknown function (DUF1593) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 393.0
TLS2_k127_4054784_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 359.0
TLS2_k127_4054784_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004178 276.0
TLS2_k127_4054784_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000427 271.0
TLS2_k127_4054784_6 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000002258 214.0
TLS2_k127_4054784_7 Integral membrane protein (intg_mem_TP0381) - - - 0.0000000000000000000000000000000000000000000000000001377 195.0
TLS2_k127_4054784_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000003219 141.0
TLS2_k127_4054784_9 - - - - 0.0000000000105 74.0
TLS2_k127_4056002_0 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 398.0
TLS2_k127_4056002_1 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 383.0
TLS2_k127_4056002_2 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 361.0
TLS2_k127_4056002_3 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 326.0
TLS2_k127_4056002_4 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 324.0
TLS2_k127_4056002_5 Belongs to the DNA photolyase family - - - 0.0000000000000000000000000000000009395 134.0
TLS2_k127_4056002_6 - - - - 0.00000000000007439 73.0
TLS2_k127_4062038_0 Arginosuccinate synthase K01940 - 6.3.4.5 3.474e-229 713.0
TLS2_k127_4062038_1 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 1.758e-214 680.0
TLS2_k127_4062038_2 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 2.552e-210 662.0
TLS2_k127_4062038_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 402.0
TLS2_k127_4062038_4 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000001737 207.0
TLS2_k127_4062038_5 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000000000000003285 184.0
TLS2_k127_4062038_6 Universal stress protein - - - 0.00000000000000000000000000000000000000000002093 172.0
TLS2_k127_4063887_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 391.0
TLS2_k127_4063887_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002689 271.0
TLS2_k127_4063887_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000002855 164.0
TLS2_k127_4063887_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000007886 105.0
TLS2_k127_4063971_0 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 621.0
TLS2_k127_4063971_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000168 288.0
TLS2_k127_4065632_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1182.0
TLS2_k127_4065632_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.96e-234 735.0
TLS2_k127_4065632_2 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001872 248.0
TLS2_k127_4065632_3 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000222 209.0
TLS2_k127_4065632_4 Heat induced stress protein YflT - - - 0.000000000000003442 86.0
TLS2_k127_4070259_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1136.0
TLS2_k127_4070259_1 Glycosyl Hydrolase Family 88 - - - 4.945e-219 688.0
TLS2_k127_4070259_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 573.0
TLS2_k127_4070259_3 Monoamine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 549.0
TLS2_k127_4070259_4 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
TLS2_k127_4070259_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002513 243.0
TLS2_k127_4070259_6 - - - - 0.00005064 49.0
TLS2_k127_4070621_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 398.0
TLS2_k127_4070621_1 - - - - 0.0000000000000000000000000000000000000000000000000000000167 203.0
TLS2_k127_4070621_2 mttA/Hcf106 family K03116 - - 0.00000000000000000000000001552 114.0
TLS2_k127_4077510_0 COG3119 Arylsulfatase A K01132 - 3.1.6.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 347.0
TLS2_k127_4077510_1 Domain of unknown function (DUF4185) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 295.0
TLS2_k127_4077510_2 Beta-lactamase - - - 0.000000000000000000000008865 102.0
TLS2_k127_4120082_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 599.0
TLS2_k127_4120082_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 548.0
TLS2_k127_4120082_2 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 475.0
TLS2_k127_4120082_3 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 386.0
TLS2_k127_4120082_4 pfam nipsnap - - - 0.000000000000000000000000000000000000000000000000000000001804 225.0
TLS2_k127_4120082_5 metallopeptidase activity K06974 - - 0.00000000000000000000000000000000000001992 150.0
TLS2_k127_4120082_6 B12 binding domain - - - 0.0000000000517 64.0
TLS2_k127_4121103_0 COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase K01007,K21787 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 586.0
TLS2_k127_4121103_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 381.0
TLS2_k127_4121103_2 Belongs to the CDS family K00981,K19664 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 0.000000000000000000000001056 106.0
TLS2_k127_4145299_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 377.0
TLS2_k127_4145299_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 359.0
TLS2_k127_4145299_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 349.0
TLS2_k127_4145299_3 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 256.0
TLS2_k127_4145299_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000001975 233.0
TLS2_k127_4145299_5 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000003086 199.0
TLS2_k127_4145299_6 domain protein K14194 - - 0.00000000000000000000000000000000000000000001235 181.0
TLS2_k127_4145299_7 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000003328 88.0
TLS2_k127_4148612_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 456.0
TLS2_k127_4148612_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000007966 215.0
TLS2_k127_4148612_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000008428 208.0
TLS2_k127_41488_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 436.0
TLS2_k127_41488_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000005894 65.0
TLS2_k127_4157134_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 579.0
TLS2_k127_4170187_0 - - - - 0.0000000000000000000000000000000000000000000000000008248 196.0
TLS2_k127_4170187_1 Belongs to the 'phage' integrase family - - - 0.000000005707 57.0
TLS2_k127_4170187_2 PAP2 superfamily - - - 0.000002231 52.0
TLS2_k127_4179398_0 Surface antigen variable number K07277 - - 0.0 1253.0
TLS2_k127_4179398_1 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005067 249.0
TLS2_k127_4179398_2 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000000000000000000006766 169.0
TLS2_k127_419135_0 Major facilitator superfamily K02429 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 549.0
TLS2_k127_419135_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 486.0
TLS2_k127_419135_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 406.0
TLS2_k127_419135_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000005298 200.0
TLS2_k127_419135_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000001552 137.0
TLS2_k127_419760_0 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000008817 245.0
TLS2_k127_419760_1 Domain of unknown function (DUF5060) - - - 0.000000000001314 80.0
TLS2_k127_4202236_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 523.0
TLS2_k127_4202236_1 arylsulfatase activity K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 375.0
TLS2_k127_4202236_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 351.0
TLS2_k127_4202236_3 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001584 277.0
TLS2_k127_4204664_0 Glycogen debranching enzyme N terminal - - - 3.449e-273 858.0
TLS2_k127_4204664_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.684e-246 777.0
TLS2_k127_4204664_2 Tetratricopeptide repeat - - - 7.296e-226 719.0
TLS2_k127_4204664_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 596.0
TLS2_k127_4204664_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000225 290.0
TLS2_k127_4204664_5 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000001169 244.0
TLS2_k127_4204664_6 signal transduction histidine kinase K13587 - 2.7.13.3 0.000000000000000000009936 96.0
TLS2_k127_4204664_7 Surface antigen - - - 0.00000000002698 76.0
TLS2_k127_4204664_8 - - - - 0.0000002418 56.0
TLS2_k127_4220830_0 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
TLS2_k127_4220830_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000008069 233.0
TLS2_k127_4220830_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000001182 240.0
TLS2_k127_4220830_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000009841 224.0
TLS2_k127_4220830_4 Putative zinc-finger - - - 0.000000000000000000000000000000000000000000000000000001365 198.0
TLS2_k127_4220830_5 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000007745 203.0
TLS2_k127_4220830_6 - - - - 0.00000000000000000000000000000000000000002225 158.0
TLS2_k127_4220830_8 - - - - 0.0000008627 58.0
TLS2_k127_4224836_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 3.331e-228 719.0
TLS2_k127_4224836_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 452.0
TLS2_k127_4224836_2 - - - - 0.00000000000000000000000000000000000000000001744 175.0
TLS2_k127_4225548_0 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 409.0
TLS2_k127_4225548_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000002212 78.0
TLS2_k127_4225548_2 - - - - 0.000000001425 68.0
TLS2_k127_4227609_0 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 463.0
TLS2_k127_4227609_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 419.0
TLS2_k127_4227609_2 membrane organization K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 297.0
TLS2_k127_4227609_3 metal cluster binding - - - 0.0000000000000000000000000000000000000000001909 164.0
TLS2_k127_4232545_0 transport - - - 8.438e-318 1007.0
TLS2_k127_4232545_1 peptidyl-tyrosine sulfation - - - 0.000000000000001083 82.0
TLS2_k127_4232545_2 - - - - 0.000000000000001919 88.0
TLS2_k127_4234815_0 TIGRFAM Flagellar hook-associated protein 3 K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 327.0
TLS2_k127_4234815_1 Bacterial flagellin C-terminal helical region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003907 265.0
TLS2_k127_4251183_0 COG0277 FAD FMN-containing dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 591.0
TLS2_k127_4251183_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008688 379.0
TLS2_k127_4251183_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000005151 150.0
TLS2_k127_4251183_3 - - - - 0.0000000325 59.0
TLS2_k127_425446_0 radical SAM domain protein K15045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 465.0
TLS2_k127_425446_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 357.0
TLS2_k127_425446_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 336.0
TLS2_k127_425446_3 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 310.0
TLS2_k127_425446_4 arylsulfatase A - - - 0.000000000000000005864 91.0
TLS2_k127_425446_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000001528 55.0
TLS2_k127_4257952_0 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 382.0
TLS2_k127_4257952_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 334.0
TLS2_k127_4257952_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 329.0
TLS2_k127_4257952_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000008666 186.0
TLS2_k127_4257952_4 Translation initiation factor 1A / IF-1 K02518 - - 0.0000000000000000000000000000000000004182 140.0
TLS2_k127_4270322_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.14e-206 650.0
TLS2_k127_4270322_1 cystathionine gamma-synthase activity K01739,K01740,K01760,K01761,K10764 - 2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 525.0
TLS2_k127_4270322_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 436.0
TLS2_k127_4270322_3 PFAM ABC transporter K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 381.0
TLS2_k127_4270322_4 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 357.0
TLS2_k127_4270322_5 Molybdate ABC transporter K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001856 280.0
TLS2_k127_4270322_6 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000004961 87.0
TLS2_k127_4276150_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 3.542e-312 968.0
TLS2_k127_4276150_1 efflux transmembrane transporter activity K02004 - - 4.426e-224 720.0
TLS2_k127_4276150_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000001711 215.0
TLS2_k127_4276150_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000009735 117.0
TLS2_k127_4276150_4 Beta-lactamase - - - 0.000000000006113 77.0
TLS2_k127_4276150_5 spheroidene biosynthetic process - - - 0.0000001391 55.0
TLS2_k127_4289118_0 Integrase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 518.0
TLS2_k127_4289118_1 Asparaginase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007781 238.0
TLS2_k127_4289118_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000001362 149.0
TLS2_k127_4291860_0 Domain of unknown function - - - 5.486e-235 736.0
TLS2_k127_4291860_1 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 324.0
TLS2_k127_4291860_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 304.0
TLS2_k127_4291860_3 ethanolamine kinase activity K07251 - 2.7.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 299.0
TLS2_k127_4291860_4 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000001219 184.0
TLS2_k127_4291860_5 Histidine kinase - - - 0.0000000000000000000000000000000000000605 158.0
TLS2_k127_4295731_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 259.0
TLS2_k127_4295731_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000071 212.0
TLS2_k127_4295731_2 Heparinase - - - 0.00000000000000000006315 94.0
TLS2_k127_4295731_3 PFAM Glycosyl transferases group 1 - - - 0.0001485 45.0
TLS2_k127_4299729_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.0 1032.0
TLS2_k127_4299729_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.908e-227 714.0
TLS2_k127_4299729_2 Alcohol dehydrogenase GroES-like domain K00148 - 1.2.1.46 8.422e-216 674.0
TLS2_k127_4299729_3 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 574.0
TLS2_k127_4299729_4 anaphase-promoting complex binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 507.0
TLS2_k127_4299729_5 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 457.0
TLS2_k127_4299729_6 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000000001147 138.0
TLS2_k127_4299729_7 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000179 76.0
TLS2_k127_4302498_0 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 515.0
TLS2_k127_4302498_1 sulfuric ester hydrolase activity K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008053 278.0
TLS2_k127_4305196_0 Transcriptional regulator K22486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001753 276.0
TLS2_k127_4305196_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852 GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000007869 231.0
TLS2_k127_4308100_0 Peptidase family M1 domain - - - 0.0 1123.0
TLS2_k127_4308100_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 2.504e-209 662.0
TLS2_k127_4308100_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.00000000000000000000000009038 119.0
TLS2_k127_4308100_11 Glycine cleavage H-protein - - - 0.0000000000000000000000002457 106.0
TLS2_k127_4308100_13 GtrA-like protein - - - 0.00000000000001619 80.0
TLS2_k127_4308100_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000009441 61.0
TLS2_k127_4308100_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 580.0
TLS2_k127_4308100_3 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 534.0
TLS2_k127_4308100_4 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 435.0
TLS2_k127_4308100_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 373.0
TLS2_k127_4308100_6 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006108 260.0
TLS2_k127_4308100_7 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000824 264.0
TLS2_k127_4308100_8 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000000002588 187.0
TLS2_k127_4317940_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 4.202e-207 657.0
TLS2_k127_4317940_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 520.0
TLS2_k127_4317940_10 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002677 259.0
TLS2_k127_4317940_11 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000004608 196.0
TLS2_k127_4317940_12 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000009327 146.0
TLS2_k127_4317940_13 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000000009789 126.0
TLS2_k127_4317940_14 Preprotein translocase, YajC K03210 - - 0.0000000000000000000000000003249 116.0
TLS2_k127_4317940_15 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000005336 109.0
TLS2_k127_4317940_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000004836 85.0
TLS2_k127_4317940_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 507.0
TLS2_k127_4317940_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 460.0
TLS2_k127_4317940_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 425.0
TLS2_k127_4317940_5 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 376.0
TLS2_k127_4317940_6 TIGRFAM TonB family K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 336.0
TLS2_k127_4317940_7 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 318.0
TLS2_k127_4317940_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 306.0
TLS2_k127_4317940_9 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 288.0
TLS2_k127_4325243_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 580.0
TLS2_k127_4325243_1 Belongs to the 'phage' integrase family - - - 0.0000000000122 66.0
TLS2_k127_4330650_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 401.0
TLS2_k127_4330650_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000009516 241.0
TLS2_k127_4331040_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 619.0
TLS2_k127_4331040_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
TLS2_k127_4331040_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000002039 139.0
TLS2_k127_4339068_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000001855 213.0
TLS2_k127_4339068_1 TIGRFAM CitB domain protein K13795 - - 0.000000000000000000000000000000007297 130.0
TLS2_k127_4339688_0 Plasmid stabilization protein ParE K19092 - - 0.000000000000000000000005449 105.0
TLS2_k127_4339688_1 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000000000001871 77.0
TLS2_k127_4339688_2 Integrase core domain - - - 0.00000005012 58.0
TLS2_k127_4343917_0 Ribosomal protein S1 K02945 - - 2.377e-246 772.0
TLS2_k127_4343917_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 366.0
TLS2_k127_4343917_2 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000001141 205.0
TLS2_k127_4343917_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000003255 166.0
TLS2_k127_4343917_4 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000001891 109.0
TLS2_k127_4343917_5 Heat induced stress protein YflT - - - 0.000000001461 67.0
TLS2_k127_4343917_6 diguanylate cyclase - - - 0.000000006422 61.0
TLS2_k127_4348986_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.733e-227 715.0
TLS2_k127_4348986_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 477.0
TLS2_k127_4348986_2 Belongs to the peptidase S41A family - - - 0.000000000000000000000000000000000000000000000000000005772 206.0
TLS2_k127_4348986_3 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.00000000000000000000000000000005502 125.0
TLS2_k127_4348986_4 - - - - 0.000000000000000004088 90.0
TLS2_k127_4356604_0 - - - - 0.0000000000000000000000000000000000000000000000000000003188 216.0
TLS2_k127_4356604_1 iron dependent repressor K01356,K03709 - 3.4.21.88 0.0000000000000000000000000000000003881 134.0
TLS2_k127_4356604_2 Integrase - - - 0.000000000000000000000000000000251 138.0
TLS2_k127_4360108_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000002803 164.0
TLS2_k127_4360108_1 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000002234 139.0
TLS2_k127_4360133_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 352.0
TLS2_k127_4360133_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 267.0
TLS2_k127_4360133_2 Bacterial PH domain - - - 0.00000006083 61.0
TLS2_k127_4360133_3 Periplasmic binding protein domain K10439 - - 0.0000229 48.0
TLS2_k127_4361635_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005922 283.0
TLS2_k127_4361635_1 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000000000000004604 211.0
TLS2_k127_4361635_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000001302 189.0
TLS2_k127_4365187_0 Belongs to the IlvD Edd family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 374.0
TLS2_k127_4365187_1 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 364.0
TLS2_k127_4365187_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 302.0
TLS2_k127_4365187_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 296.0
TLS2_k127_4365187_4 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000301 244.0
TLS2_k127_4365187_5 phosphorelay signal transduction system - - - 0.000000000000000000000000000003966 124.0
TLS2_k127_4367465_0 Oxidoreductase FAD-binding domain K00351 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 538.0
TLS2_k127_4367465_1 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 525.0
TLS2_k127_4367465_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 414.0
TLS2_k127_4367465_3 electron transport chain K00347 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 294.0
TLS2_k127_4367465_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000005893 259.0
TLS2_k127_4367465_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000002228 242.0
TLS2_k127_4367465_6 Rnf-Nqr subunit, membrane protein K00349 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000005345 211.0
TLS2_k127_4367465_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.00000000000000000000000000000000000000000000009577 178.0
TLS2_k127_4367465_8 Protein conserved in bacteria - - - 0.00000000001071 73.0
TLS2_k127_4371506_0 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 396.0
TLS2_k127_4371506_1 synthase K06044 - 5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 342.0
TLS2_k127_4371506_2 4-alpha-glucanotransferase K00700,K00705,K02438,K06044 - 2.4.1.18,2.4.1.25,3.2.1.196,5.4.99.15 0.00000000000000000000000000000000000000000000207 172.0
TLS2_k127_4371506_3 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 0.00000000000000000000000000000000000000000002091 165.0
TLS2_k127_4371506_4 TIGRFAM malto-oligosyltrehalose trehalohydrolase K01236 - 3.2.1.141 0.0000000000000000000000000000001682 123.0
TLS2_k127_4371506_5 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016787,GO:0016798,GO:0030978,GO:0030980,GO:0033942,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0071704,GO:1901575,GO:1901576 3.2.1.141 0.00001148 53.0
TLS2_k127_4371859_0 Two component signalling adaptor domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 434.0
TLS2_k127_4371859_1 PFAM histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 397.0
TLS2_k127_4371859_2 chemotaxis protein methyltransferase K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 379.0
TLS2_k127_4371859_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 359.0
TLS2_k127_4371859_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000008195 235.0
TLS2_k127_4371859_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000000001966 103.0
TLS2_k127_4371859_6 chemotaxis protein CheV K03408,K03415 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.00000596 55.0
TLS2_k127_4376497_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 505.0
TLS2_k127_4376497_1 PFAM Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000005579 245.0
TLS2_k127_4376497_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000002327 183.0
TLS2_k127_4376497_3 surface antigen K07277 - - 0.0000000000000000000000000003428 123.0
TLS2_k127_4376497_4 chorismate mutase - - - 0.000000000000000000000000001491 116.0
TLS2_k127_4376497_5 Transcriptional regulator crp fnr family K10914 - - 0.00000000000002319 82.0
TLS2_k127_4381966_0 Tryptophan halogenase K14266 - 1.14.19.9 4.048e-227 713.0
TLS2_k127_4381966_1 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 517.0
TLS2_k127_4386344_0 Protein of unknown function (DUF229) - - - 3.093e-206 651.0
TLS2_k127_4386344_1 Belongs to the BshC family K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 505.0
TLS2_k127_4386344_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 394.0
TLS2_k127_4386344_3 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 344.0
TLS2_k127_4386344_4 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 320.0
TLS2_k127_4386344_5 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009162 274.0
TLS2_k127_4386344_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000004005 218.0
TLS2_k127_4386344_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000009766 178.0
TLS2_k127_4386344_8 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000002581 151.0
TLS2_k127_4386344_9 membrane transporter protein K07090 - - 0.00000000000000002086 91.0
TLS2_k127_4389855_0 Radical SAM - - - 0.0 1124.0
TLS2_k127_4396017_0 domain protein - - - 0.0 1083.0
TLS2_k127_4396017_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 569.0
TLS2_k127_4396017_2 Aldo/keto reductase family K18471 - - 0.0000000000000000000000000000000000000000000000000000000000000298 224.0
TLS2_k127_4396017_3 domain protein K14475 - - 0.000000000000000001372 102.0
TLS2_k127_4402557_0 Cytochrome c K00117,K02030,K17760,K19713 - 1.1.5.2,1.1.9.1,1.8.2.2 1.359e-281 877.0
TLS2_k127_4402557_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 511.0
TLS2_k127_4402557_10 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000009404 243.0
TLS2_k127_4402557_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000002235 191.0
TLS2_k127_4402557_12 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.0000000000000000000000000000000000000000000005128 170.0
TLS2_k127_4402557_13 Flavodoxin-like fold K03809 - 1.6.5.2 0.00000000000000000000000000000000000000211 148.0
TLS2_k127_4402557_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000002869 156.0
TLS2_k127_4402557_15 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000001159 125.0
TLS2_k127_4402557_17 lyase activity - - - 0.00000000000000000005242 101.0
TLS2_k127_4402557_18 - - - - 0.00003012 50.0
TLS2_k127_4402557_2 COG3119 Arylsulfatase A K01132 - 3.1.6.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 458.0
TLS2_k127_4402557_3 Pirin C-terminal cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 419.0
TLS2_k127_4402557_4 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 351.0
TLS2_k127_4402557_5 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 297.0
TLS2_k127_4402557_6 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 292.0
TLS2_k127_4402557_7 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007044 273.0
TLS2_k127_4402557_8 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002985 259.0
TLS2_k127_4402557_9 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004741 240.0
TLS2_k127_4403917_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.167e-235 750.0
TLS2_k127_4403917_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 3.647e-234 738.0
TLS2_k127_4403917_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.19e-207 649.0
TLS2_k127_4403917_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 267.0
TLS2_k127_4403917_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000002116 241.0
TLS2_k127_4403917_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001231 218.0
TLS2_k127_4403917_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000001337 202.0
TLS2_k127_4403917_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000003589 150.0
TLS2_k127_4407373_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000006162 224.0
TLS2_k127_4407373_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000001152 216.0
TLS2_k127_4407373_2 KAP family P-loop domain - - - 0.000000000000000000000000000000000000000001233 173.0
TLS2_k127_4407373_3 Tetratricopeptide repeat - - - 0.00000001594 59.0
TLS2_k127_4407616_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004155 264.0
TLS2_k127_4407616_1 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000006481 219.0
TLS2_k127_4407616_2 PIN domain - - - 0.000000000000000000000000000003017 124.0
TLS2_k127_4407616_3 CopG domain protein DNA-binding domain protein - - - 0.0000000003311 63.0
TLS2_k127_4416102_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006979 236.0
TLS2_k127_4416102_1 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000003342 206.0
TLS2_k127_4416102_2 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000000000000000000000000000000000000001295 183.0
TLS2_k127_4419318_0 Methyltransferase - - - 3.278e-197 622.0
TLS2_k127_4419318_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 405.0
TLS2_k127_4419318_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 387.0
TLS2_k127_4422511_0 TonB-dependent receptor - - - 1.006e-279 900.0
TLS2_k127_4422511_1 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 613.0
TLS2_k127_4422511_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 580.0
TLS2_k127_4422511_3 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 549.0
TLS2_k127_4422511_4 arylsulfatase activity K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003801 287.0
TLS2_k127_4424448_0 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 3.462e-233 730.0
TLS2_k127_4424448_1 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 5.497e-196 623.0
TLS2_k127_4424448_2 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 436.0
TLS2_k127_4424448_3 ABC-type sugar transport system, periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 434.0
TLS2_k127_4424448_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 383.0
TLS2_k127_4424448_5 Binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 332.0
TLS2_k127_4424448_6 cephalosporin-C deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009727 251.0
TLS2_k127_4424448_7 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000003922 232.0
TLS2_k127_4424448_8 Belongs to the glycosyl hydrolase family 6 K01179,K01181,K01218,K19668 - 3.2.1.4,3.2.1.78,3.2.1.8,3.2.1.91 0.00000000000000000000000000000000000000000000002221 184.0
TLS2_k127_4424448_9 Cobalamin (vitamin B12) biosynthesis CbiX protein - - - 0.000000000000000000000000000000000000000000004383 175.0
TLS2_k127_4425180_0 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 549.0
TLS2_k127_4425180_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 505.0
TLS2_k127_4425180_10 cobalamin-transporting ATPase activity - - - 0.0000000000000005271 83.0
TLS2_k127_4425180_11 - - - - 0.00000002456 59.0
TLS2_k127_4425180_2 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 346.0
TLS2_k127_4425180_3 Sigma-70, region 4 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 297.0
TLS2_k127_4425180_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004632 289.0
TLS2_k127_4425180_5 TonB C terminal - - - 0.000000000000000000000000000000000000000000000000000005569 203.0
TLS2_k127_4425180_6 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000002613 154.0
TLS2_k127_4425180_7 Trehalose utilisation - - - 0.0000000000000000000000000353 115.0
TLS2_k127_4425180_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000001314 109.0
TLS2_k127_4425180_9 TonB-dependent receptor - - - 0.0000000000000000000007315 99.0
TLS2_k127_4431179_0 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 503.0
TLS2_k127_4431179_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 374.0
TLS2_k127_4431179_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 366.0
TLS2_k127_4431179_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 362.0
TLS2_k127_4431179_4 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 329.0
TLS2_k127_4431179_5 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000001288 182.0
TLS2_k127_4433541_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1163.0
TLS2_k127_4433541_1 TonB-dependent receptor - - - 6.508e-277 891.0
TLS2_k127_4433541_10 - - - - 0.000000000000000000002784 100.0
TLS2_k127_4433541_2 Cytochrome c - - - 2.11e-217 704.0
TLS2_k127_4433541_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 608.0
TLS2_k127_4433541_4 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 405.0
TLS2_k127_4433541_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 392.0
TLS2_k127_4433541_6 PFAM Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 353.0
TLS2_k127_4433541_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003139 267.0
TLS2_k127_4433541_8 cell redox homeostasis - - - 0.0000000000000000000000000000001173 129.0
TLS2_k127_4433541_9 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000103 114.0
TLS2_k127_4436460_0 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 445.0
TLS2_k127_4436460_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 413.0
TLS2_k127_4436460_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000001598 178.0
TLS2_k127_4436460_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000001282 170.0
TLS2_k127_4436460_4 amine dehydrogenase activity K14274 - - 0.000000000000004231 89.0
TLS2_k127_4436460_5 efflux protein, MATE family K03327 - - 0.000000007407 57.0
TLS2_k127_4437285_0 DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 329.0
TLS2_k127_4437285_1 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000001585 222.0
TLS2_k127_4437285_2 - - - - 0.0000000000000000000000000000005571 124.0
TLS2_k127_4443217_0 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 485.0
TLS2_k127_4443217_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000007544 219.0
TLS2_k127_4443822_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 306.0
TLS2_k127_444615_0 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 370.0
TLS2_k127_444615_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000003945 185.0
TLS2_k127_444615_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000005889 181.0
TLS2_k127_444615_3 arylsulfatase A - - - 0.0000000000000000000000000000000000002566 145.0
TLS2_k127_4448716_0 Thermophilic metalloprotease (M29) - - - 0.00000008848 59.0
TLS2_k127_4458587_0 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 410.0
TLS2_k127_4458587_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003248 264.0
TLS2_k127_4459909_0 COG3119 Arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 514.0
TLS2_k127_4459909_1 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 507.0
TLS2_k127_4459909_2 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 500.0
TLS2_k127_4459909_3 LOR/SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 448.0
TLS2_k127_4459909_4 COGs COG0673 dehydrogenase and related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 365.0
TLS2_k127_4459909_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000002922 196.0
TLS2_k127_4459909_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000001234 178.0
TLS2_k127_4462299_0 PFAM zinc iron permease K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
TLS2_k127_4470202_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.31e-201 636.0
TLS2_k127_4470202_1 phosphorelay sensor kinase activity K07709,K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 424.0
TLS2_k127_4470202_2 Tellurite resistance protein TehB - - - 0.00000000000000000001009 98.0
TLS2_k127_4478851_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 546.0
TLS2_k127_4478851_1 PFAM tRNA rRNA methyltransferase, SpoU K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 288.0
TLS2_k127_4478851_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000005138 231.0
TLS2_k127_4478851_3 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000001679 171.0
TLS2_k127_4481219_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1084.0
TLS2_k127_4481219_1 amino acid K03294 - - 2.413e-220 692.0
TLS2_k127_4481219_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 331.0
TLS2_k127_4481219_3 PEGA domain - - - 0.00000000000000000000000002496 116.0
TLS2_k127_4492491_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 599.0
TLS2_k127_4492491_1 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 594.0
TLS2_k127_4492491_10 Response regulator, receiver - - - 0.00000000000000000000000000000000000000003844 161.0
TLS2_k127_4492491_11 Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system K02013 - 3.6.3.34 0.0000000000000000006836 97.0
TLS2_k127_4492491_12 Sulfatase - - - 0.00000001602 57.0
TLS2_k127_4492491_2 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 474.0
TLS2_k127_4492491_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 294.0
TLS2_k127_4492491_4 helix_turn_helix isocitrate lyase regulation K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001942 268.0
TLS2_k127_4492491_5 - K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006126 266.0
TLS2_k127_4492491_6 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 258.0
TLS2_k127_4492491_7 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007515 245.0
TLS2_k127_4492491_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002235 226.0
TLS2_k127_4492491_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000003621 179.0
TLS2_k127_4494480_0 glyoxalase bleomycin resistance protein dioxygenase K15242,K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 445.0
TLS2_k127_4494480_1 Phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000002666 237.0
TLS2_k127_4494480_2 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000003526 117.0
TLS2_k127_4494480_3 CHAT domain - - - 0.000000000001419 70.0
TLS2_k127_4498470_0 integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001379 258.0
TLS2_k127_4498470_1 IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000001698 154.0
TLS2_k127_4498470_3 Transposase - - - 0.0000008115 52.0
TLS2_k127_4498669_0 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 439.0
TLS2_k127_4498669_1 TonB dependent receptor K16089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 450.0
TLS2_k127_4498669_2 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 306.0
TLS2_k127_4498669_3 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001542 288.0
TLS2_k127_4498669_4 COG0526 Thiol-disulfide isomerase and thioredoxins K02199 - - 0.00000000000001245 81.0
TLS2_k127_4498669_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00000004872 62.0
TLS2_k127_4499286_0 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 429.0
TLS2_k127_4499286_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 356.0
TLS2_k127_4500780_0 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 392.0
TLS2_k127_4500780_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003961 273.0
TLS2_k127_4500780_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003262 240.0
TLS2_k127_4500780_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000003506 101.0
TLS2_k127_4500780_4 Cytochrome BD ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.00000000002571 67.0
TLS2_k127_4500780_5 MerR HTH family regulatory protein K18997 - - 0.00001457 51.0
TLS2_k127_4501118_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 403.0
TLS2_k127_4501118_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 400.0
TLS2_k127_4501118_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 294.0
TLS2_k127_4501118_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004882 258.0
TLS2_k127_4501118_4 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000356 247.0
TLS2_k127_4501118_5 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000008566 222.0
TLS2_k127_4501118_6 PFAM Cupin - - - 0.000000000000000000000000000000000000000000000005698 175.0
TLS2_k127_4501118_7 Helix-turn-helix domain K15539 - - 0.0000000000000000000000000003987 128.0
TLS2_k127_4501315_0 cobalamin-transporting ATPase activity - - - 0.0 1238.0
TLS2_k127_4501315_1 alginic acid biosynthetic process K01729 - 4.2.2.3 3.041e-318 985.0
TLS2_k127_4501315_2 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002372 254.0
TLS2_k127_4501315_3 PFAM acyl-coA-binding protein, ACBP - - - 0.0000000000000000000000000000387 119.0
TLS2_k127_4501315_4 beta-propeller repeat - - - 0.00000000000000000006551 97.0
TLS2_k127_4501315_5 - - - - 0.0006192 51.0
TLS2_k127_4508546_0 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004495 234.0
TLS2_k127_4508546_1 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000002983 209.0
TLS2_k127_4508546_2 Domain of unknown function (DUF2382) - - - 0.00000000000000000000000008114 111.0
TLS2_k127_4518858_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K01342,K08651,K14645,K14743,K20486,K20754 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009405,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0031224,GO:0031226,GO:0032879,GO:0040007,GO:0043170,GO:0044238,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0051046,GO:0051049,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.21.111,3.4.21.62,3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 376.0
TLS2_k127_4518858_1 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
TLS2_k127_4518858_2 response regulator, receiver - - - 0.00000000000000000000004579 105.0
TLS2_k127_4524180_0 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 488.0
TLS2_k127_4525718_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 433.0
TLS2_k127_4525718_1 Leucine Rich repeat - - - 0.0000002235 59.0
TLS2_k127_4526520_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 554.0
TLS2_k127_4526520_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 535.0
TLS2_k127_4526520_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 388.0
TLS2_k127_4526520_3 - - - - 0.0000000000000000000000000000000000000000000000000000001035 215.0
TLS2_k127_4526520_4 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000008472 111.0
TLS2_k127_4529757_0 Carboxypeptidase regulatory-like domain - - - 0.0 1035.0
TLS2_k127_4529757_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 460.0
TLS2_k127_4529757_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001027 269.0
TLS2_k127_4529757_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000003213 199.0
TLS2_k127_4529757_4 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000001703 198.0
TLS2_k127_4529757_5 N-acetyltransferase K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000004379 188.0
TLS2_k127_4529757_6 S1/P1 Nuclease - - - 0.00000000000000000000000000000000000001303 160.0
TLS2_k127_4529757_7 Belongs to the UPF0102 family K07460 - - 0.000000000000007958 78.0
TLS2_k127_4530433_0 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 460.0
TLS2_k127_4530433_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 330.0
TLS2_k127_4530433_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 306.0
TLS2_k127_4530433_3 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 313.0
TLS2_k127_4530433_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000008844 225.0
TLS2_k127_4537974_0 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
TLS2_k127_4537974_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009235 287.0
TLS2_k127_4537974_2 PFAM Peptidase M56, BlaR1 - - - 0.000000000000000000000000000000000000000000000000000002225 217.0
TLS2_k127_4537974_3 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000001378 154.0
TLS2_k127_4537974_4 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000003758 151.0
TLS2_k127_4537974_5 amidohydrolase - - - 0.000000000000000000000001227 104.0
TLS2_k127_4537974_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0002096 46.0
TLS2_k127_4549757_0 choline dehydrogenase activity - - - 4.991e-288 891.0
TLS2_k127_4549757_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 584.0
TLS2_k127_4549757_2 TIGRFAM luciferase family oxidoreductase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 376.0
TLS2_k127_4549757_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000004175 127.0
TLS2_k127_4560324_0 DNA-K related protein - - - 0.0 1010.0
TLS2_k127_4560324_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 638.0
TLS2_k127_4560324_2 Glycerol dehydrogenase and related enzymes K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 424.0
TLS2_k127_4560324_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 391.0
TLS2_k127_4560324_4 HAD-superfamily hydrolase, subfamily IB K08966 - 3.1.3.87 0.00000000000000000000000000000000000000000000000000000000001404 215.0
TLS2_k127_4560324_5 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000004503 183.0
TLS2_k127_4560324_6 - - - - 0.00000000000000000000000000000000000006495 149.0
TLS2_k127_4560324_7 - - - - 0.000000000000000000000000000000001426 138.0
TLS2_k127_4568647_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 398.0
TLS2_k127_4568647_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 286.0
TLS2_k127_457707_0 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000002298 247.0
TLS2_k127_457707_1 Resolvase - - - 0.000000000000000000000000000000000000000000000000008557 184.0
TLS2_k127_457707_2 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000001241 157.0
TLS2_k127_457707_3 and related - - - 0.00000000000000000001913 95.0
TLS2_k127_457707_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000003263 75.0
TLS2_k127_457707_5 - - - - 0.0000000004924 68.0
TLS2_k127_4577282_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 330.0
TLS2_k127_4577282_1 Amidohydrolase K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 306.0
TLS2_k127_4577282_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000006522 211.0
TLS2_k127_4577282_3 TIGRFAM molybdenum cofactor synthesis - - - 0.0000000000000000000000000000000000000000000000001183 182.0
TLS2_k127_4577282_5 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000004978 138.0
TLS2_k127_4577596_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.964e-231 735.0
TLS2_k127_4577596_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 442.0
TLS2_k127_4577596_2 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 425.0
TLS2_k127_4577596_3 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 394.0
TLS2_k127_4577596_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000668 252.0
TLS2_k127_4577596_5 (ABC) transporter K06147,K06148 - - 0.000000000000000000000000000000000000000000001992 168.0
TLS2_k127_4577596_6 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000001966 147.0
TLS2_k127_4594236_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 475.0
TLS2_k127_4594236_1 Lanthionine synthetase C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 362.0
TLS2_k127_4594236_2 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 301.0
TLS2_k127_4594236_3 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 312.0
TLS2_k127_4594236_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001568 252.0
TLS2_k127_4594236_5 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000001862 208.0
TLS2_k127_4599700_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.968e-213 671.0
TLS2_k127_4599700_1 Family of unknown function (DUF438) K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 524.0
TLS2_k127_4599700_10 hydroperoxide reductase activity - - - 0.00000000000000000000000101 106.0
TLS2_k127_4599700_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000821 58.0
TLS2_k127_4599700_12 carboxymuconolactone decarboxylase K07486 - - 0.00008191 48.0
TLS2_k127_4599700_2 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 454.0
TLS2_k127_4599700_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 417.0
TLS2_k127_4599700_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 418.0
TLS2_k127_4599700_5 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 324.0
TLS2_k127_4599700_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000001753 217.0
TLS2_k127_4599700_8 Domain of unknown function (DUF1858) - - - 0.000000000000000000000000000001245 126.0
TLS2_k127_4599700_9 VanZ like family - - - 0.00000000000000000000000000001869 131.0
TLS2_k127_460247_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 507.0
TLS2_k127_460247_1 COG COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 313.0
TLS2_k127_460247_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003628 268.0
TLS2_k127_460247_3 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000119 222.0
TLS2_k127_4607141_0 unidirectional conjugation K03205 - - 0.0 1009.0
TLS2_k127_4607141_1 single-stranded DNA binding K03111 - - 0.0000000000000000000000000000000000000000000000000000000001459 206.0
TLS2_k127_4607141_2 Domain of unknown function (DUF1738) - - - 0.0000000000000000000000000000000000000000000000000000000001518 209.0
TLS2_k127_4607141_3 Type IV secretory pathway protease TraF - - - 0.000000000000000000000000000000000000000000000000003247 193.0
TLS2_k127_4607141_4 Carbon-nitrogen hydrolase - - - 0.0000000000001848 79.0
TLS2_k127_4608278_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 3.244e-210 664.0
TLS2_k127_4608278_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 471.0
TLS2_k127_4608278_2 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 401.0
TLS2_k127_4609214_0 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 306.0
TLS2_k127_4609214_1 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008005 273.0
TLS2_k127_4609214_2 Vitamin K epoxide reductase family - - - 0.0000000000000000000000001156 109.0
TLS2_k127_4609214_3 - - - - 0.00000000000000000001348 99.0
TLS2_k127_4609214_4 bacterial OsmY and nodulation domain K04065 - - 0.0000000000000004459 80.0
TLS2_k127_4609214_5 BON domain - - - 0.0000000000000004998 82.0
TLS2_k127_461286_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 510.0
TLS2_k127_461286_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 493.0
TLS2_k127_461286_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000374 302.0
TLS2_k127_461286_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000001055 211.0
TLS2_k127_461286_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000008447 106.0
TLS2_k127_461286_5 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000001339 118.0
TLS2_k127_461286_6 Belongs to the IlvD Edd family K22396 - 4.2.1.82 0.00001739 54.0
TLS2_k127_461523_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.673e-299 944.0
TLS2_k127_461523_1 class II (D K K01893 - 6.1.1.22 1.757e-241 751.0
TLS2_k127_461523_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 554.0
TLS2_k127_461523_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 527.0
TLS2_k127_461523_4 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 425.0
TLS2_k127_461523_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 425.0
TLS2_k127_461523_6 PFAM Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 361.0
TLS2_k127_461523_7 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009345 258.0
TLS2_k127_461523_8 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003755 239.0
TLS2_k127_461523_9 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000006782 155.0
TLS2_k127_462650_0 - - - - 0.000000000000000000000000000000000000000000000000000007216 206.0
TLS2_k127_462650_1 - - - - 0.000000000000000000000000000000000000000000007336 177.0
TLS2_k127_462650_2 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000001557 158.0
TLS2_k127_462650_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000401 153.0
TLS2_k127_462650_4 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000005328 117.0
TLS2_k127_4627236_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000009273 208.0
TLS2_k127_4629174_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 557.0
TLS2_k127_4629174_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 339.0
TLS2_k127_4629174_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 301.0
TLS2_k127_4629174_3 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000000000000000000000000007477 147.0
TLS2_k127_4629174_4 - - - - 0.00000000000000000000000000000007938 138.0
TLS2_k127_4630632_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 342.0
TLS2_k127_4630632_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000009874 226.0
TLS2_k127_4631475_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 410.0
TLS2_k127_4631475_1 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000009512 198.0
TLS2_k127_4638231_0 Putative glutamine amidotransferase - - - 3.124e-199 639.0
TLS2_k127_4638231_1 Aerotolerance regulator N-terminal - - - 0.000000000231 64.0
TLS2_k127_4649917_0 Carboxypeptidase regulatory-like domain - - - 3.767e-300 955.0
TLS2_k127_4649917_1 MacB-like periplasmic core domain - - - 2.052e-233 750.0
TLS2_k127_4649917_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 7.86e-202 637.0
TLS2_k127_4649917_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 507.0
TLS2_k127_4649917_4 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 353.0
TLS2_k127_4649917_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 347.0
TLS2_k127_4649917_6 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000005097 143.0
TLS2_k127_4672702_0 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 315.0
TLS2_k127_4672702_1 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 299.0
TLS2_k127_4672702_2 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002213 284.0
TLS2_k127_4672702_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001204 259.0
TLS2_k127_4672702_4 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006642 244.0
TLS2_k127_4672702_6 - - - - 0.00000000000000000000000000000000000000000009561 165.0
TLS2_k127_4677162_0 Cytochrome c - - - 5.412e-251 797.0
TLS2_k127_4677162_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 488.0
TLS2_k127_4677162_2 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 415.0
TLS2_k127_4677739_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 407.0
TLS2_k127_4677739_1 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
TLS2_k127_4677739_2 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000009935 222.0
TLS2_k127_4677739_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000002313 142.0
TLS2_k127_4677739_4 - - - - 0.00001142 55.0
TLS2_k127_4680448_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002854 251.0
TLS2_k127_4680448_1 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000004012 165.0
TLS2_k127_4680448_2 PFAM SpoVT AbrB K07172 - - 0.0000000000000000000000001809 109.0
TLS2_k127_4680448_3 SnoaL-like polyketide cyclase K07255 - - 0.0000004776 58.0
TLS2_k127_4685022_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 8.427e-225 706.0
TLS2_k127_4685022_1 GMC oxidoreductase - - - 1.395e-200 635.0
TLS2_k127_4685022_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 362.0
TLS2_k127_4685022_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 319.0
TLS2_k127_4685022_4 Likely ribonuclease with RNase H fold. K07447 - - 0.000000000000000000000000000000000000000000001099 169.0
TLS2_k127_4685022_5 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000000000000000000007616 149.0
TLS2_k127_4685022_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000006974 136.0
TLS2_k127_4685022_7 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000002252 134.0
TLS2_k127_4686837_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 448.0
TLS2_k127_4686837_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 355.0
TLS2_k127_4686837_2 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 328.0
TLS2_k127_4694610_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 578.0
TLS2_k127_4694610_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 530.0
TLS2_k127_4694610_2 ParB-like nuclease domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 338.0
TLS2_k127_4694610_3 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000003458 198.0
TLS2_k127_4694610_5 amine dehydrogenase activity K12132 - 2.7.11.1 0.000000000000000000002722 111.0
TLS2_k127_4696527_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000001238 232.0
TLS2_k127_4696527_1 - - - - 0.0000000000000000003897 96.0
TLS2_k127_4696527_2 Erythromycin esterase K06880 - - 0.00002618 48.0
TLS2_k127_4699346_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001368 286.0
TLS2_k127_4699346_1 - - - - 0.00000000000000000000000000000000000000000000215 171.0
TLS2_k127_4699346_2 - - - - 0.0000000000000000000000000000000000000000447 157.0
TLS2_k127_4699346_3 cell wall glycoprotein biosynthetic process - - - 0.00000000000000000000000000006873 131.0
TLS2_k127_4699346_4 Putative cyclase - - - 0.000000000000004649 75.0
TLS2_k127_470932_0 COG3119 Arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 449.0
TLS2_k127_470932_1 Prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001138 263.0
TLS2_k127_470932_2 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000001444 198.0
TLS2_k127_470932_3 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000002176 132.0
TLS2_k127_470932_4 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000006356 100.0
TLS2_k127_470932_5 heme binding - - - 0.0000000000000001148 88.0
TLS2_k127_470932_6 peptidase activity K03046,K21471 - 2.7.7.6 0.00000000000102 77.0
TLS2_k127_4713414_0 FtsX-like permease family - - - 0.0 1456.0
TLS2_k127_4713414_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000000000003138 211.0
TLS2_k127_4719743_0 PFAM Transposase IS66 family K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005285 290.0
TLS2_k127_4726014_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 584.0
TLS2_k127_4726014_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 513.0
TLS2_k127_4726014_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 489.0
TLS2_k127_4726014_3 Domain of unknown function (DUF1738) - - - 0.0000000000000000000000000000000000000000000000000000000005037 203.0
TLS2_k127_4726014_4 Domain of unknown function (DUF1738) - - - 0.0000001034 55.0
TLS2_k127_4728139_0 PFAM TonB-dependent Receptor Plug - - - 9.604e-312 975.0
TLS2_k127_4728139_1 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 530.0
TLS2_k127_4731815_0 Belongs to the glycosyl hydrolase 43 family K01198 - 3.2.1.37 9.303e-236 734.0
TLS2_k127_4731815_1 Amidohydrolase family - - - 0.000000000000000000002938 94.0
TLS2_k127_4734390_0 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 610.0
TLS2_k127_4734390_1 sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 568.0
TLS2_k127_4734390_10 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000002978 125.0
TLS2_k127_4734390_11 Cytochrome c - - - 0.00000000000000000000000002765 116.0
TLS2_k127_4734390_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 536.0
TLS2_k127_4734390_3 Glycosyltransferase family 28 C-terminal domain K03715 - 2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 499.0
TLS2_k127_4734390_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 494.0
TLS2_k127_4734390_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 400.0
TLS2_k127_4734390_6 polysaccharide biosynthetic process K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
TLS2_k127_4734390_7 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001139 280.0
TLS2_k127_4734390_8 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000003113 257.0
TLS2_k127_4734390_9 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000002825 231.0
TLS2_k127_4737450_0 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 516.0
TLS2_k127_4737450_1 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 317.0
TLS2_k127_4737450_2 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000002493 166.0
TLS2_k127_4741837_0 Belongs to the TPP enzyme family K00156 - 1.2.5.1 3.488e-269 839.0
TLS2_k127_4741837_1 Glucoamylase and related glycosyl hydrolases - - - 8.604e-243 764.0
TLS2_k127_4741837_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 350.0
TLS2_k127_4741837_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000005925 194.0
TLS2_k127_4741837_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000002566 160.0
TLS2_k127_4741837_5 electron transfer activity K02275,K02305,K08738,K17223 - 1.9.3.1 0.000000000000000000000000000007585 124.0
TLS2_k127_4741837_6 Carboxypeptidase regulatory-like domain - - - 0.00000000003904 68.0
TLS2_k127_4742598_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 567.0
TLS2_k127_4742598_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 315.0
TLS2_k127_4742598_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005449 280.0
TLS2_k127_4742598_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000227 228.0
TLS2_k127_4742598_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000765 209.0
TLS2_k127_4742598_5 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000145 203.0
TLS2_k127_4742598_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000007364 80.0
TLS2_k127_4742598_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001175 77.0
TLS2_k127_4742598_8 Domain of unknown function (DUF3459) K00700 - 2.4.1.18 0.0000001062 60.0
TLS2_k127_4746412_0 amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000004156 176.0
TLS2_k127_4746412_1 zinc ion binding K12035 - 2.3.2.27 0.00005537 56.0
TLS2_k127_4746412_2 Amidohydrolase K03392 - 4.1.1.45 0.0003703 43.0
TLS2_k127_4758039_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 8.821e-218 679.0
TLS2_k127_4758039_1 PFAM Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 300.0
TLS2_k127_4761_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 437.0
TLS2_k127_4761_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001709 259.0
TLS2_k127_4761_2 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000006981 239.0
TLS2_k127_4761_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000005277 202.0
TLS2_k127_4773132_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 553.0
TLS2_k127_4773132_1 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 315.0
TLS2_k127_4773132_2 - - - - 0.00000000000000000000000000000000000006172 152.0
TLS2_k127_4773132_3 methyltransferase - - - 0.00000000000000000000000152 106.0
TLS2_k127_4773132_4 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000006492 108.0
TLS2_k127_4773132_5 Domain of unknown function (DUF4440) - - - 0.0000007104 57.0
TLS2_k127_4780970_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 569.0
TLS2_k127_4780970_1 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 369.0
TLS2_k127_4780970_2 Membrane - - - 0.0000000001068 70.0
TLS2_k127_4781583_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 363.0
TLS2_k127_4781583_1 PFAM Response regulator receiver domain - - - 0.00000000000000000000001525 102.0
TLS2_k127_4781583_2 phosphorelay signal transduction system - - - 0.00001101 53.0
TLS2_k127_4796044_0 Histidine kinase K02478 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000006075 200.0
TLS2_k127_4796044_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000007842 178.0
TLS2_k127_4800067_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 362.0
TLS2_k127_4800067_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
TLS2_k127_4800067_2 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000002173 191.0
TLS2_k127_4805899_0 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000003846 191.0
TLS2_k127_4805899_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000001637 82.0
TLS2_k127_4805899_2 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000002557 51.0
TLS2_k127_4807491_0 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 595.0
TLS2_k127_4807491_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 379.0
TLS2_k127_4807491_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 318.0
TLS2_k127_4807491_3 DNA-binding transcription factor activity K21703 - - 0.000003141 53.0
TLS2_k127_4810069_0 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
TLS2_k127_4810069_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000001996 233.0
TLS2_k127_4810069_3 NmrA-like family - - - 0.0000000000000000000000000000000002208 136.0
TLS2_k127_4810069_5 DinB superfamily - - - 0.00000001822 64.0
TLS2_k127_4811864_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 506.0
TLS2_k127_4811864_1 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 347.0
TLS2_k127_4811864_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 327.0
TLS2_k127_4811864_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000002114 271.0
TLS2_k127_4811864_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004896 276.0
TLS2_k127_4811864_6 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000001139 193.0
TLS2_k127_4811864_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000001518 207.0
TLS2_k127_4811864_8 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000009408 179.0
TLS2_k127_4816667_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 2.203e-280 874.0
TLS2_k127_4816667_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 479.0
TLS2_k127_4816667_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 484.0
TLS2_k127_4816667_3 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 411.0
TLS2_k127_4816667_4 BNR repeat-containing family member - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 302.0
TLS2_k127_4816667_5 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 301.0
TLS2_k127_4816667_6 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000007019 207.0
TLS2_k127_4816667_7 - - - - 0.0000000000000000000000000000000000000000000000000003754 197.0
TLS2_k127_4816667_8 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000001725 72.0
TLS2_k127_4826377_0 Protein of unknown function (DUF1549) - - - 1.402e-282 879.0
TLS2_k127_4834482_0 PFAM TonB-dependent Receptor Plug - - - 2.025e-277 891.0
TLS2_k127_4834482_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 584.0
TLS2_k127_4834482_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 551.0
TLS2_k127_4834482_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 574.0
TLS2_k127_4834482_4 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 336.0
TLS2_k127_4834482_5 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000005661 242.0
TLS2_k127_4834482_6 STAS domain K04749 - - 0.0000000000000000000000000000000000000000000001799 173.0
TLS2_k127_4834482_7 Redoxin - - - 0.0000000000000000000000000702 109.0
TLS2_k127_4834482_8 Amidohydrolase family - - - 0.00000000000479 67.0
TLS2_k127_4843678_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 568.0
TLS2_k127_4843678_1 Integrase core domain - - - 0.0000000000000000000000000000000000000000002152 159.0
TLS2_k127_4849968_0 protocatechuate 3,4-dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 608.0
TLS2_k127_4849968_1 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002407 291.0
TLS2_k127_4851853_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 429.0
TLS2_k127_4851853_1 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 353.0
TLS2_k127_4852292_0 Carboxypeptidase regulatory-like domain - - - 2.137e-271 871.0
TLS2_k127_4852292_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 355.0
TLS2_k127_4854896_0 Polyketide synthase of type I - - - 9.578e-238 770.0
TLS2_k127_4854896_1 non-ribosomal peptide synthetase K16416 - - 0.00000000000000000004264 93.0
TLS2_k127_48562_0 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 505.0
TLS2_k127_48562_1 Alkylhydroperoxidase AhpD family core domain-containing protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000188 205.0
TLS2_k127_48562_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000001089 154.0
TLS2_k127_4857156_0 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 458.0
TLS2_k127_4857156_1 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 423.0
TLS2_k127_4857156_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 312.0
TLS2_k127_4868294_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.354e-225 702.0
TLS2_k127_4868294_1 Acetyl xylan esterase (AXE1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 300.0
TLS2_k127_4868294_2 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000001605 188.0
TLS2_k127_4868294_3 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000006594 110.0
TLS2_k127_4868912_0 PFAM ABC transporter K11085 - - 4.693e-231 733.0
TLS2_k127_4868912_1 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 626.0
TLS2_k127_4868912_10 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 344.0
TLS2_k127_4868912_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 323.0
TLS2_k127_4868912_12 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002244 285.0
TLS2_k127_4868912_13 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000315 264.0
TLS2_k127_4868912_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000376 215.0
TLS2_k127_4868912_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000001809 213.0
TLS2_k127_4868912_16 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000005241 179.0
TLS2_k127_4868912_17 - - - - 0.00000000000000000000000000000000000000000002002 184.0
TLS2_k127_4868912_18 Hfq protein - - - 0.000000000000000000000000000000001432 133.0
TLS2_k127_4868912_19 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000212 131.0
TLS2_k127_4868912_2 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 582.0
TLS2_k127_4868912_20 Trm112p-like protein K09791 - - 0.0000000000000000000003074 96.0
TLS2_k127_4868912_21 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000003168 96.0
TLS2_k127_4868912_3 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 584.0
TLS2_k127_4868912_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 519.0
TLS2_k127_4868912_5 phosphoglucosamine mutase activity K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 488.0
TLS2_k127_4868912_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 455.0
TLS2_k127_4868912_7 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 396.0
TLS2_k127_4868912_8 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 382.0
TLS2_k127_4868912_9 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 354.0
TLS2_k127_4869059_0 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 384.0
TLS2_k127_4869059_1 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 378.0
TLS2_k127_4869059_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 351.0
TLS2_k127_4869059_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001336 260.0
TLS2_k127_4869059_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000003084 156.0
TLS2_k127_4870510_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007084 286.0
TLS2_k127_4870510_1 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.0000000000000003663 81.0
TLS2_k127_4870510_2 PFAM natural resistance-associated macrophage protein K03322 - - 0.0005102 43.0
TLS2_k127_4871291_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 307.0
TLS2_k127_4871291_1 Galactose oxidase, central domain - - - 0.00000000000000000000000002602 111.0
TLS2_k127_4884236_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 355.0
TLS2_k127_4884236_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001307 278.0
TLS2_k127_4884236_2 protein transport across the cell outer membrane K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000104 275.0
TLS2_k127_4884236_3 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000000000000000000000000000000000000000000000000003738 226.0
TLS2_k127_488883_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000004427 198.0
TLS2_k127_4889540_0 PFAM Xylose isomerase K01820 - 5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 582.0
TLS2_k127_4889540_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000006915 55.0
TLS2_k127_4891093_0 DDE superfamily endonuclease - - - 0.0000000000000000000000241 100.0
TLS2_k127_4891093_2 zinc-finger binding domain of transposase IS66 K07484 - - 0.00002848 47.0
TLS2_k127_4910021_0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 296.0
TLS2_k127_4910021_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001552 269.0
TLS2_k127_4910021_2 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000005314 199.0
TLS2_k127_4910021_3 manually curated - - - 0.000000000000000000000000000000000000000000704 160.0
TLS2_k127_4918020_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 320.0
TLS2_k127_4918020_1 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009105 271.0
TLS2_k127_4918020_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000001907 125.0
TLS2_k127_4919629_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 4.353e-206 650.0
TLS2_k127_4919629_1 Belongs to the sigma-70 factor family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 597.0
TLS2_k127_4919629_2 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004858 236.0
TLS2_k127_4919629_3 Domain of unknown function (DUF4357) - - - 0.000000000000000000000000000000000000000000000000000000000000000006998 228.0
TLS2_k127_4919629_4 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.0000000000000000000000000000000000000000000001081 173.0
TLS2_k127_4919629_5 YCII-related domain - - - 0.0000000000000000000000000000002369 130.0
TLS2_k127_4919629_6 Domain of unknown function (DUF4357) - - - 0.000000000000000000000000001487 113.0
TLS2_k127_4919653_0 Domain of unknown function (DUF3552) K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 602.0
TLS2_k127_4919653_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 448.0
TLS2_k127_4919653_2 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 304.0
TLS2_k127_4919653_3 - - - - 0.00000000000000000000000000000002469 129.0
TLS2_k127_4919653_4 - - - - 0.0000000000000000000006752 95.0
TLS2_k127_4919653_5 - - - - 0.000000000000000002043 87.0
TLS2_k127_4927829_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000768 180.0
TLS2_k127_4927829_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000006114 141.0
TLS2_k127_4927829_2 - - - - 0.0000000016 64.0
TLS2_k127_4927829_3 OmpA family - - - 0.0000006807 54.0
TLS2_k127_4929963_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 543.0
TLS2_k127_4929963_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890,K06878 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 499.0
TLS2_k127_4931673_0 PFAM LmbE family protein - - - 4.225e-200 642.0
TLS2_k127_4931673_1 Sodium:solute symporter family - - - 8.948e-195 621.0
TLS2_k127_4931673_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 293.0
TLS2_k127_4931673_3 - - - - 0.00000001413 64.0
TLS2_k127_4957914_0 multi-organism process K03195 - - 0.00000000000000000000000000000000000000000000000000000000000008958 228.0
TLS2_k127_4957914_1 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000009956 212.0
TLS2_k127_4957914_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000003439 166.0
TLS2_k127_4957914_3 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000004907 113.0
TLS2_k127_4957914_4 Hemerythrin HHE cation binding domain - - - 0.00000000000008643 79.0
TLS2_k127_4959678_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 486.0
TLS2_k127_4959678_1 PFAM Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005837 263.0
TLS2_k127_4959678_2 helix_turn_helix, Lux Regulon K03088 - - 0.00000000000000000000000000000000000009893 147.0
TLS2_k127_4959678_3 Anti-sigma factor - - - 0.000001839 61.0
TLS2_k127_4965689_0 Uncharacterized protein family (UPF0051) K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 536.0
TLS2_k127_4965689_1 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 416.0
TLS2_k127_4965689_2 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000003918 179.0
TLS2_k127_4970434_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 517.0
TLS2_k127_4970434_1 Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 444.0
TLS2_k127_4970434_2 AAA domain - - - 0.00000000000004698 74.0
TLS2_k127_4980364_0 Dienelactone hydrolase family - - - 2.201e-264 827.0
TLS2_k127_4980364_1 TIGRFAM gluconate transporter K06155,K06157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 419.0
TLS2_k127_4980364_2 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006443 286.0
TLS2_k127_4980407_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 483.0
TLS2_k127_4980407_1 mevalonate kinase activity K00869,K00938,K16190 - 2.7.1.36,2.7.1.43,2.7.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 429.0
TLS2_k127_4980407_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 301.0
TLS2_k127_4987208_0 TonB-dependent receptor - - - 2.666e-215 689.0
TLS2_k127_4987208_1 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K17213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 389.0
TLS2_k127_4987208_2 Belongs to the binding-protein-dependent transport system permease family K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 368.0
TLS2_k127_4989973_0 phage integrase domain protein SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 491.0
TLS2_k127_4989973_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 485.0
TLS2_k127_4989973_2 phage integrase domain protein SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 458.0
TLS2_k127_4989973_3 PFAM Resolvase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 314.0
TLS2_k127_4989973_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000005328 129.0
TLS2_k127_4989973_5 Belongs to the 'phage' integrase family - - - 0.0000000000007607 68.0
TLS2_k127_4989973_6 Calcium binding - - - 0.0001259 48.0
TLS2_k127_4994178_0 Insulinase (Peptidase family M16) - - - 6.328e-199 631.0
TLS2_k127_4994178_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 604.0
TLS2_k127_4994178_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 594.0
TLS2_k127_4994178_3 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 496.0
TLS2_k127_4994178_4 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 445.0
TLS2_k127_4994178_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 387.0
TLS2_k127_4994178_6 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 346.0
TLS2_k127_4994178_7 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 346.0
TLS2_k127_4994178_8 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 353.0
TLS2_k127_4998510_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 523.0
TLS2_k127_4998510_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003937 286.0
TLS2_k127_5001088_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 577.0
TLS2_k127_5001088_1 AAA domain - - - 0.00000000000000004091 89.0
TLS2_k127_500645_0 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 301.0
TLS2_k127_500645_1 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000003087 220.0
TLS2_k127_500645_2 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000005505 165.0
TLS2_k127_500645_3 protocatechuate 3,4-dioxygenase activity - - - 0.000000000000000000000002603 109.0
TLS2_k127_500645_4 PFAM pentapeptide repeat protein - - - 0.0000000000001202 77.0
TLS2_k127_5014728_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 404.0
TLS2_k127_5014728_1 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003052 250.0
TLS2_k127_5018879_0 Circularly permuted ATP-grasp type 2 - - - 1.945e-243 760.0
TLS2_k127_5018879_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 437.0
TLS2_k127_5018879_2 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 428.0
TLS2_k127_5018879_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 404.0
TLS2_k127_5018879_4 - K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 383.0
TLS2_k127_5018879_5 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001533 276.0
TLS2_k127_5018879_6 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002632 278.0
TLS2_k127_5018879_7 NmrA-like family - - - 0.000000000000000001327 99.0
TLS2_k127_5019738_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 592.0
TLS2_k127_5019738_1 Pfam Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 403.0
TLS2_k127_5019738_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006921 266.0
TLS2_k127_5021011_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 2.809e-225 706.0
TLS2_k127_5021011_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.245e-220 709.0
TLS2_k127_5021011_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 424.0
TLS2_k127_5021011_3 - - - - 0.000000000000000000000000000000000000003512 152.0
TLS2_k127_5021011_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000005885 140.0
TLS2_k127_5021011_5 NYN domain - - - 0.000000000000000000000000000003033 131.0
TLS2_k127_5022049_0 Type VI secretion system, TssF K11896 - - 3.079e-264 826.0
TLS2_k127_5022049_1 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 6.117e-258 802.0
TLS2_k127_5022049_2 ImpA, N-terminal, type VI secretion system K11902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 495.0
TLS2_k127_5022049_3 type VI secretion protein, VC_A0111 family K11895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 381.0
TLS2_k127_5022049_4 ImpE protein K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 311.0
TLS2_k127_5022049_5 PFAM Uncharacterised conserved protein UCP028301 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004239 250.0
TLS2_k127_5022049_6 Gene 25-like lysozyme K11897 - - 0.0000000000000000000000000000000000000000000000000002335 189.0
TLS2_k127_5022049_7 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000003513 163.0
TLS2_k127_5022049_8 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.000000000000000000000000000000000000002059 149.0
TLS2_k127_5026911_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000009127 203.0
TLS2_k127_5026911_1 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000001096 169.0
TLS2_k127_5026911_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0005679 45.0
TLS2_k127_5031_0 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 505.0
TLS2_k127_5031_1 phage integrase domain protein SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 323.0
TLS2_k127_5031_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 302.0
TLS2_k127_5031_3 - - - - 0.00000000000000000000000000000000000000000002357 166.0
TLS2_k127_5031_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.0000000000000000000004222 96.0
TLS2_k127_5035840_0 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003915 239.0
TLS2_k127_5035840_1 COG3335 Transposase and inactivated derivatives K07494 - - 0.000000000000000000006638 92.0
TLS2_k127_5035840_2 InterPro IPR002559 - - - 0.0000000000000001538 80.0
TLS2_k127_5035840_3 NHL repeat - - - 0.00001191 57.0
TLS2_k127_5035840_4 Winged helix-turn helix - - - 0.0004317 43.0
TLS2_k127_5036727_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.172e-286 891.0
TLS2_k127_5036727_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 6.489e-257 814.0
TLS2_k127_5036727_2 Carboxypeptidase regulatory-like domain - - - 1.349e-250 825.0
TLS2_k127_5036727_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 472.0
TLS2_k127_5036727_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13639 - - 0.00000000000000000000000000000000000000000000000000000000000000000006472 234.0
TLS2_k127_5036727_5 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000002863 226.0
TLS2_k127_5036727_6 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000004161 203.0
TLS2_k127_5036727_7 NUDIX domain - - - 0.000000000000000000000000000000000000000000000002078 183.0
TLS2_k127_5036727_8 Cation transport regulator - - - 0.00000000000000000000000001212 118.0
TLS2_k127_5040857_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1223.0
TLS2_k127_5047284_0 PFAM oxidoreductase domain protein - - - 4.064e-203 641.0
TLS2_k127_5047284_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 563.0
TLS2_k127_5047284_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000006164 101.0
TLS2_k127_5049391_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 342.0
TLS2_k127_5049391_1 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000007385 172.0
TLS2_k127_5052017_0 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000002295 173.0
TLS2_k127_5056602_0 Carboxypeptidase regulatory-like domain - - - 0.0 1410.0
TLS2_k127_5056602_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 6.986e-230 731.0
TLS2_k127_5059749_0 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 567.0
TLS2_k127_5059749_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 491.0
TLS2_k127_5059749_2 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 424.0
TLS2_k127_5059749_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008451 278.0
TLS2_k127_5059749_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000004495 187.0
TLS2_k127_5059749_5 Biotin-lipoyl like - - - 0.00000000000000000000005749 102.0
TLS2_k127_5063246_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1082.0
TLS2_k127_5063246_1 synthase K06044 - 5.4.99.15 0.000000000000000000000000000001413 121.0
TLS2_k127_5063736_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 519.0
TLS2_k127_5063736_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 503.0
TLS2_k127_5063736_10 Hemerythrin K07216 - - 0.0003254 48.0
TLS2_k127_5063736_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 487.0
TLS2_k127_5063736_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 374.0
TLS2_k127_5063736_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 345.0
TLS2_k127_5063736_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 305.0
TLS2_k127_5063736_7 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.000000000000000000000000000000000000000000009647 166.0
TLS2_k127_5063736_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000001946 123.0
TLS2_k127_5063975_0 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 2.583e-201 634.0
TLS2_k127_5063975_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 554.0
TLS2_k127_5063975_2 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 429.0
TLS2_k127_5063975_3 SMART Resolvase, RNase H domain protein fold K06959 - - 0.00000000000000000000000000000000000000000000000000000007958 198.0
TLS2_k127_5066398_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 557.0
TLS2_k127_5066398_1 Protein of unknown function (DUF1593) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 510.0
TLS2_k127_5066398_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
TLS2_k127_5066398_3 Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 320.0
TLS2_k127_5066398_4 dihydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003638 225.0
TLS2_k127_5067258_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 528.0
TLS2_k127_5067258_1 reductase K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 522.0
TLS2_k127_5067258_2 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 455.0
TLS2_k127_5067258_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 368.0
TLS2_k127_5079674_0 MoeZ MoeB domain K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 429.0
TLS2_k127_5079674_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 358.0
TLS2_k127_5079674_2 surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000002293 217.0
TLS2_k127_5080939_0 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 542.0
TLS2_k127_5080939_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000001562 184.0
TLS2_k127_5086369_0 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001239 250.0
TLS2_k127_5086369_1 HI0933-like protein - - - 0.000000000000000000000000000000000000002204 153.0
TLS2_k127_5086369_2 BNR repeat-like domain - - - 0.0000000000000000000000000006155 119.0
TLS2_k127_5086473_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1249.0
TLS2_k127_5086473_1 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 472.0
TLS2_k127_5086473_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 303.0
TLS2_k127_5086473_3 5-oxoprolinase (ATP-hydrolyzing) activity K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000162 231.0
TLS2_k127_5086473_4 L-rhamnose mutarotase K03534 - 5.1.3.32 0.0000000000000000000000000000000000000000002615 161.0
TLS2_k127_5086473_5 Involved in the tonB-independent uptake of proteins - - - 0.00005842 50.0
TLS2_k127_5090906_0 Glycosyl transferases group 1 - - - 3.664e-314 981.0
TLS2_k127_5090906_1 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 612.0
TLS2_k127_5090906_2 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 587.0
TLS2_k127_5090906_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 381.0
TLS2_k127_5090906_4 extracellular polysaccharide biosynthetic process K00568,K03561,K07011,K20444 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 358.0
TLS2_k127_5090906_5 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004034 270.0
TLS2_k127_5090906_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000004254 234.0
TLS2_k127_5090906_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000002172 89.0
TLS2_k127_5092472_0 PFAM Integrase catalytic - - - 6.703e-254 791.0
TLS2_k127_5092472_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 422.0
TLS2_k127_5092472_2 Transposase - - - 0.000000000000002608 75.0
TLS2_k127_51113_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 366.0
TLS2_k127_51113_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 330.0
TLS2_k127_51113_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001216 269.0
TLS2_k127_51113_3 Belongs to the HesB IscA family - - - 0.00000000000000000000000000000000000000000000000001725 181.0
TLS2_k127_51113_4 - - - - 0.0000000000000000000000000000002564 128.0
TLS2_k127_51113_6 His Kinase A (phosphoacceptor) domain - - - 0.0000001585 62.0
TLS2_k127_5114703_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 606.0
TLS2_k127_5114703_1 Gmc oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 443.0
TLS2_k127_5114703_2 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 347.0
TLS2_k127_5114703_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008647 271.0
TLS2_k127_5114703_4 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002632 278.0
TLS2_k127_5114703_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000001133 218.0
TLS2_k127_5114703_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001003 220.0
TLS2_k127_5114703_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000001341 216.0
TLS2_k127_5114703_8 self proteolysis - - - 0.000000000000000000000000000001773 128.0
TLS2_k127_5122405_0 Ankyrin repeats (many copies) K06015,K06867,K06886 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 436.0
TLS2_k127_5122405_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 387.0
TLS2_k127_5122405_2 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 340.0
TLS2_k127_5122405_3 Two component regulator propeller K19694 - - 0.00000000000000000000000000000000000000000000000002028 203.0
TLS2_k127_5122405_4 TIR domain - - - 0.000000000000000000000000000000000000000000000611 179.0
TLS2_k127_5122405_5 - - - - 0.0000000000000000000213 92.0
TLS2_k127_5122405_6 Plasmid encoded RepA protein - - - 0.000000000000000002877 88.0
TLS2_k127_5123117_0 TonB dependent receptor - - - 0.0 1594.0
TLS2_k127_5123117_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1146.0
TLS2_k127_5123117_10 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 298.0
TLS2_k127_5123117_11 tRNA wobble adenosine to inosine editing K01487,K11991 - 3.5.4.3,3.5.4.33 0.0000000000000000000000000000000000000000000000000004107 194.0
TLS2_k127_5123117_12 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000006295 167.0
TLS2_k127_5123117_13 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000002267 153.0
TLS2_k127_5123117_14 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000003885 140.0
TLS2_k127_5123117_15 cell redox homeostasis - - - 0.000000000000000000000000000000001088 135.0
TLS2_k127_5123117_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.0 1027.0
TLS2_k127_5123117_3 D-arabinono-1,4-lactone oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 589.0
TLS2_k127_5123117_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 556.0
TLS2_k127_5123117_5 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 538.0
TLS2_k127_5123117_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 525.0
TLS2_k127_5123117_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 470.0
TLS2_k127_5123117_8 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 460.0
TLS2_k127_5123117_9 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 428.0
TLS2_k127_5123878_0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 351.0
TLS2_k127_5123878_1 Pfam:Methyltransf_26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002513 253.0
TLS2_k127_5123878_2 Pfam:Methyltransf_26 - - - 0.0000000000000000000000000000000000000000000000000000598 210.0
TLS2_k127_5125538_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.122e-213 675.0
TLS2_k127_5125538_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000001342 161.0
TLS2_k127_5125538_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000008188 107.0
TLS2_k127_5127020_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 542.0
TLS2_k127_5127020_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 489.0
TLS2_k127_5127020_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 458.0
TLS2_k127_5127020_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 413.0
TLS2_k127_5127020_4 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 327.0
TLS2_k127_5127020_5 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 320.0
TLS2_k127_5127020_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006766 245.0
TLS2_k127_5127020_7 Haloacid dehalogenase-like hydrolase K11777 - - 0.00000000000000000000000000000000000000000000000000000000000000002898 232.0
TLS2_k127_5127020_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000002062 118.0
TLS2_k127_5127020_9 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000761 86.0
TLS2_k127_5148926_0 Cytochrome c - - - 2.286e-253 796.0
TLS2_k127_5148926_1 long-chain fatty acid transporting porin activity - - - 9.926e-223 700.0
TLS2_k127_5148926_2 - - - - 0.00000000000000000000000000000000000004158 151.0
TLS2_k127_5166342_0 WD40 domain protein beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 366.0
TLS2_k127_5166342_1 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 332.0
TLS2_k127_5166342_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000676 134.0
TLS2_k127_5166342_3 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.0000000000000000000000008884 109.0
TLS2_k127_5166342_4 MacB-like periplasmic core domain - - - 0.0000000000000002613 84.0
TLS2_k127_5170302_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 612.0
TLS2_k127_5170302_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 386.0
TLS2_k127_5170302_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 372.0
TLS2_k127_5170302_3 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001898 278.0
TLS2_k127_5170302_4 - - - - 0.0000000000000000000000000000000000000000000000002136 184.0
TLS2_k127_5170332_0 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 385.0
TLS2_k127_5170332_1 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 342.0
TLS2_k127_5170332_2 domain, Protein K03112 - - 0.00000000000000000000000000000004719 137.0
TLS2_k127_5170332_3 Domain of unknown function (DUF4440) - - - 0.000607 47.0
TLS2_k127_5172853_0 TonB-dependent receptor - - - 1.148e-309 987.0
TLS2_k127_5172853_1 Cytochrome c, class I - - - 2.704e-272 858.0
TLS2_k127_5172853_2 carboxylic acid catabolic process K12661 - 4.2.1.90 5.898e-216 676.0
TLS2_k127_5172853_3 Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000859 162.0
TLS2_k127_5172853_4 Metal ion binding. It is involved in the biological process described with oxidation-reduction process K11173 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006103,GO:0006520,GO:0006536,GO:0006538,GO:0006539,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0047988,GO:0051186,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.99.24 0.000000000000000000000000000000000000005026 147.0
TLS2_k127_5173621_0 membrane organization K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 621.0
TLS2_k127_5173621_1 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 313.0
TLS2_k127_5173621_10 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000008042 102.0
TLS2_k127_5173621_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 289.0
TLS2_k127_5173621_3 FecCD transport family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005954 282.0
TLS2_k127_5173621_5 Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000007381 271.0
TLS2_k127_5173621_6 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000006794 208.0
TLS2_k127_5173621_7 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000009537 204.0
TLS2_k127_5173621_8 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000001222 188.0
TLS2_k127_5173621_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000002955 132.0
TLS2_k127_5174443_0 RNA binding K06959 - - 1.13e-278 867.0
TLS2_k127_5183332_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 467.0
TLS2_k127_5183332_1 nitrite reductase [NAD(P)H] activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 295.0
TLS2_k127_5183332_2 Protein of unknown function (DUF1501) - - - 0.00000000000003324 72.0
TLS2_k127_5185325_0 - - - - 1.784e-215 681.0
TLS2_k127_5185325_1 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 360.0
TLS2_k127_5187184_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1019.0
TLS2_k127_5187184_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 1.99e-224 709.0
TLS2_k127_5187184_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 441.0
TLS2_k127_5187184_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 413.0
TLS2_k127_5187184_4 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000000000000000000001456 214.0
TLS2_k127_5187184_5 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000001714 192.0
TLS2_k127_5188361_0 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.0000000000000000000000000000000000018 143.0
TLS2_k127_5188361_1 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000006374 133.0
TLS2_k127_5188361_2 Phage shock protein C, PspC K03973 - - 0.0000000000000000000005335 99.0
TLS2_k127_5188361_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000002495 96.0
TLS2_k127_5188361_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000002877 61.0
TLS2_k127_5189843_0 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000009036 256.0
TLS2_k127_5189843_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000002789 114.0
TLS2_k127_5199104_0 ASPIC and UnbV - - - 2.053e-251 786.0
TLS2_k127_5199104_1 polysaccharide catabolic process K01179 - 3.2.1.4 9.152e-212 674.0
TLS2_k127_5199104_2 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 351.0
TLS2_k127_5199104_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000379 204.0
TLS2_k127_5199104_4 Cytochrome P460 - - - 0.000000003998 60.0
TLS2_k127_5199104_5 Tetratricopeptide repeat - - - 0.00002287 46.0
TLS2_k127_5210976_0 Glycosyl hydrolases family 15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 491.0
TLS2_k127_5210976_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 430.0
TLS2_k127_5211648_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 4.3e-264 818.0
TLS2_k127_5211648_1 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 628.0
TLS2_k127_5211648_2 PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 603.0
TLS2_k127_5211648_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 427.0
TLS2_k127_5211648_4 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 413.0
TLS2_k127_5211648_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008353 251.0
TLS2_k127_5211648_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000009482 219.0
TLS2_k127_5221840_0 TonB-dependent Receptor Plug Domain - - - 0.0 1346.0
TLS2_k127_5221840_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 477.0
TLS2_k127_5221840_10 protein conserved in bacteria containing thioredoxin-like domain - - - 0.0004132 44.0
TLS2_k127_5221840_2 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 479.0
TLS2_k127_5221840_3 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 432.0
TLS2_k127_5221840_4 Cupin superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 339.0
TLS2_k127_5221840_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000003479 242.0
TLS2_k127_5221840_6 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000000000001492 231.0
TLS2_k127_5221840_7 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000000000007546 141.0
TLS2_k127_5221840_8 Low molecular weight phosphatase family - - - 0.000000000000000000000002894 109.0
TLS2_k127_522346_0 Plasmid encoded RepA protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 419.0
TLS2_k127_522346_1 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.000000000000000000000000000000001192 133.0
TLS2_k127_522346_2 Helix-turn-helix domain K07726 - - 0.000000000000000000009981 95.0
TLS2_k127_522346_3 - - - - 0.00000001602 57.0
TLS2_k127_5223868_0 Phenylalanine-4-hydroxylase K00500 GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 451.0
TLS2_k127_5223868_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 417.0
TLS2_k127_5223868_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 354.0
TLS2_k127_5223868_3 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 305.0
TLS2_k127_5223868_4 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005599 278.0
TLS2_k127_5223868_5 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006683 252.0
TLS2_k127_5223868_6 Tetratricopeptide repeat - - - 0.000000000000003135 78.0
TLS2_k127_5230714_0 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 393.0
TLS2_k127_5230714_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 363.0
TLS2_k127_5230714_2 Protein of unknown function (DUF3108) - - - 0.000007389 48.0
TLS2_k127_5231747_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 370.0
TLS2_k127_5231747_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001458 282.0
TLS2_k127_5231747_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005171 247.0
TLS2_k127_5231747_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000006821 119.0
TLS2_k127_5231747_4 Redoxin - - - 0.00000000000000000001597 101.0
TLS2_k127_5231747_5 Domain of unknown function (DUF2382) - - - 0.000000000000001004 86.0
TLS2_k127_5231747_6 protein kinase activity - - - 0.000000000000001149 90.0
TLS2_k127_5231747_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000123 52.0
TLS2_k127_5231747_8 Disulphide bond corrector protein DsbC - - - 0.00009689 53.0
TLS2_k127_5234342_0 non-ribosomal peptide synthetase K16416 - - 3.707e-210 692.0
TLS2_k127_5234342_1 Plasmid encoded RepA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 298.0
TLS2_k127_5234342_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007511 249.0
TLS2_k127_5234342_3 Condensation domain - - - 0.000000000000000000000000003443 115.0
TLS2_k127_5234342_4 Transcriptional regulator, AbiEi antitoxin, Type IV TA system - - - 0.00000000000000000003984 100.0
TLS2_k127_5234342_5 transposase IS116 IS110 IS902 family - - - 0.000000000001366 71.0
TLS2_k127_5234342_6 protein conserved in bacteria - - - 0.00000000001514 76.0
TLS2_k127_5238304_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000002131 160.0
TLS2_k127_5238304_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000003083 148.0
TLS2_k127_5240228_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 426.0
TLS2_k127_5240228_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 397.0
TLS2_k127_5240228_2 - - - - 0.0000000000000000000000000000000000000000000000001709 186.0
TLS2_k127_5240228_3 response regulator, receiver - - - 0.000000000000000000000000000000001055 136.0
TLS2_k127_5240463_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005661 278.0
TLS2_k127_5240463_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000004233 123.0
TLS2_k127_5243367_0 Elongation factor G, domain IV K02355 - - 2.794e-249 779.0
TLS2_k127_5243367_1 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000006653 141.0
TLS2_k127_525179_0 Cytochrome c - - - 4.227e-310 971.0
TLS2_k127_525179_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.526e-289 901.0
TLS2_k127_525179_10 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000000000001525 165.0
TLS2_k127_525179_11 - - - - 0.000000000000000000000000000000000005769 146.0
TLS2_k127_525179_12 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000003504 134.0
TLS2_k127_525179_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000006919 111.0
TLS2_k127_525179_14 Cation efflux family - - - 0.00000000002238 65.0
TLS2_k127_525179_2 Protein of unknown function (DUF1501) - - - 3.523e-233 728.0
TLS2_k127_525179_3 protein kinase activity K08884 - 2.7.11.1 3.194e-226 731.0
TLS2_k127_525179_4 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 6.401e-214 685.0
TLS2_k127_525179_5 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 509.0
TLS2_k127_525179_6 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 367.0
TLS2_k127_525179_7 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000005375 235.0
TLS2_k127_525179_8 Alkaline and neutral invertase - - - 0.000000000000000000000000000000000000000000000000000000000000000008856 239.0
TLS2_k127_525179_9 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000006395 183.0
TLS2_k127_5252173_0 ABC transporter transmembrane K18889 - - 7.325e-255 797.0
TLS2_k127_5252173_1 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000001574 188.0
TLS2_k127_5252173_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000001199 133.0
TLS2_k127_5255654_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1039.0
TLS2_k127_5255654_1 Cytochrome c - - - 8.281e-289 914.0
TLS2_k127_5255654_2 Protein of unknown function (DUF1501) - - - 3.774e-223 700.0
TLS2_k127_5255654_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000001093 156.0
TLS2_k127_5255654_4 TIGRFAM Malto-oligosyltrehalose synthase K06044 - 5.4.99.15 0.00000000000000000000000000006571 117.0
TLS2_k127_5255654_5 DinB superfamily - - - 0.0000000000000000000001675 106.0
TLS2_k127_5255654_6 domain, Protein - - - 0.0000000001136 76.0
TLS2_k127_5255654_7 COG2931 RTX toxins and related Ca2 -binding proteins K01406 - 3.4.24.40 0.000001713 63.0
TLS2_k127_5255654_8 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0001832 56.0
TLS2_k127_5256689_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 618.0
TLS2_k127_5256689_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000008123 234.0
TLS2_k127_5256689_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000001804 116.0
TLS2_k127_5257102_0 PLD-like domain K06131 - - 1.237e-222 702.0
TLS2_k127_5257102_1 PFAM Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 571.0
TLS2_k127_5257102_2 NHL repeat - - - 0.000000000000007565 85.0
TLS2_k127_5257102_3 cell adhesion involved in biofilm formation - - - 0.000004907 58.0
TLS2_k127_5261727_0 tail sheath protein - - - 1.026e-269 857.0
TLS2_k127_5261727_1 DNA photolyase activity K03716 - 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 508.0
TLS2_k127_5261727_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 433.0
TLS2_k127_5261727_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000292 156.0
TLS2_k127_5261727_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000002415 78.0
TLS2_k127_5261727_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576,GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.000000000001884 72.0
TLS2_k127_5263218_0 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 361.0
TLS2_k127_5263218_1 transposition K00986,K07497 - 2.7.7.49 0.00000000000000000000000000000000000001447 161.0
TLS2_k127_5263218_2 COG2963 Transposase and inactivated derivatives - - - 0.0000000000002431 74.0
TLS2_k127_5272043_0 acyl-CoA dehydrogenase activity - - - 5.076e-258 806.0
TLS2_k127_5272043_1 Acyl transferase domain - - - 1.689e-212 666.0
TLS2_k127_5272043_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 419.0
TLS2_k127_5272043_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 402.0
TLS2_k127_5272043_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 333.0
TLS2_k127_5272043_5 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 306.0
TLS2_k127_5272043_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002699 265.0
TLS2_k127_5272043_7 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000002845 239.0
TLS2_k127_5272043_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000002521 121.0
TLS2_k127_5277653_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 477.0
TLS2_k127_5277653_1 HlyD family secretion protein K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002747 256.0
TLS2_k127_5279747_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 508.0
TLS2_k127_5279747_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 448.0
TLS2_k127_5279747_2 1-deoxy-D-xylulose-5-phosphate synthase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 426.0
TLS2_k127_5279747_3 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 372.0
TLS2_k127_5279747_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 347.0
TLS2_k127_5279747_5 response regulator K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 338.0
TLS2_k127_5279747_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008749 257.0
TLS2_k127_5279747_7 Histidine kinase K11617 - 2.7.13.3 0.00000000000000000000000000000000000000000000004219 178.0
TLS2_k127_5279747_8 PFAM Radical SAM - - - 0.000000000000000000000002375 103.0
TLS2_k127_5282824_0 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 9.816e-224 702.0
TLS2_k127_5282824_1 Putative esterase K07214 - - 1.859e-195 612.0
TLS2_k127_5282824_2 mRNA binding - - - 0.00000000000000302 76.0
TLS2_k127_5282824_3 - - - - 0.000000000104 68.0
TLS2_k127_5282824_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000009944 49.0
TLS2_k127_5287499_0 Penicillin amidase K01434 - 3.5.1.11 9.58e-284 888.0
TLS2_k127_5287499_1 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 350.0
TLS2_k127_5296951_0 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
TLS2_k127_5296951_1 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000000000000000000000000004486 177.0
TLS2_k127_5296951_2 Resolvase domain - - - 0.0000000000000004526 81.0
TLS2_k127_5296951_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000003774 72.0
TLS2_k127_5297080_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 616.0
TLS2_k127_5297080_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000009239 175.0
TLS2_k127_53053_0 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000002451 223.0
TLS2_k127_53053_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000004427 203.0
TLS2_k127_53053_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000001743 216.0
TLS2_k127_53053_3 HTTM domain protein - - - 0.00000000000000000000001388 105.0
TLS2_k127_53053_4 DinB family - - - 0.0000001668 57.0
TLS2_k127_5309819_0 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 546.0
TLS2_k127_5309819_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 541.0
TLS2_k127_5309819_2 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
TLS2_k127_5309819_3 PFAM Ribonuclease BN-like family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001104 266.0
TLS2_k127_5309819_4 photoreceptor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000007357 246.0
TLS2_k127_5309819_5 - - - - 0.0000000000000000000000000000000000000000000003221 179.0
TLS2_k127_5309819_6 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000008252 120.0
TLS2_k127_5343654_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 2.716e-249 790.0
TLS2_k127_5343654_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.694e-219 685.0
TLS2_k127_5343654_2 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 479.0
TLS2_k127_5343654_4 PFAM glucosamine galactosamine-6-phosphate isomerase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003891 274.0
TLS2_k127_5343654_5 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000217 268.0
TLS2_k127_5343654_6 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000006544 178.0
TLS2_k127_5343654_7 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000002412 151.0
TLS2_k127_5343654_8 Transposase - - - 0.0001057 49.0
TLS2_k127_5353545_0 Glycosyltransferase like family 2 K20444 - - 7.73e-247 793.0
TLS2_k127_5371653_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.961e-250 792.0
TLS2_k127_5371653_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 6.699e-211 662.0
TLS2_k127_5371653_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001797 248.0
TLS2_k127_5371653_11 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002384 216.0
TLS2_k127_5371653_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000006399 198.0
TLS2_k127_5371653_13 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000006588 170.0
TLS2_k127_5371653_14 molybdenum cofactor guanylyltransferase activity K03637,K03752,K13818 - 2.7.7.77,4.6.1.17 0.000000000000000000000000000001222 131.0
TLS2_k127_5371653_15 - - - - 0.000000001299 71.0
TLS2_k127_5371653_2 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 576.0
TLS2_k127_5371653_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 591.0
TLS2_k127_5371653_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 546.0
TLS2_k127_5371653_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 537.0
TLS2_k127_5371653_6 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 407.0
TLS2_k127_5371653_7 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 368.0
TLS2_k127_5371653_8 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 342.0
TLS2_k127_5371653_9 Phytase K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 301.0
TLS2_k127_5373470_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 337.0
TLS2_k127_5373470_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 302.0
TLS2_k127_5373470_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003983 277.0
TLS2_k127_5373470_3 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 261.0
TLS2_k127_5373470_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000001226 171.0
TLS2_k127_5373470_5 - - - - 0.0000000009147 65.0
TLS2_k127_5373470_6 - - - - 0.00000000136 59.0
TLS2_k127_5374472_0 alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 303.0
TLS2_k127_5374472_1 Protein of unknown function (DUF229) - - - 0.0000000000000000000000000000000000000000000002362 186.0
TLS2_k127_5374472_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000126 67.0
TLS2_k127_537879_0 COG3119 Arylsulfatase A and related enzymes K01135 - 3.1.6.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 544.0
TLS2_k127_537879_1 PFAM multi antimicrobial extrusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000001933 219.0
TLS2_k127_5380238_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 6.17e-207 647.0
TLS2_k127_5380238_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 612.0
TLS2_k127_5380238_10 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000001114 195.0
TLS2_k127_5380238_11 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000000000000000000000000000000005754 195.0
TLS2_k127_5380238_12 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000001318 147.0
TLS2_k127_5380238_13 - - - - 0.00000000000000000000000005417 117.0
TLS2_k127_5380238_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 599.0
TLS2_k127_5380238_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 546.0
TLS2_k127_5380238_4 domain, Protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 519.0
TLS2_k127_5380238_5 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 411.0
TLS2_k127_5380238_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 381.0
TLS2_k127_5380238_7 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 340.0
TLS2_k127_5380238_8 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 317.0
TLS2_k127_5380238_9 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000001742 202.0
TLS2_k127_5383238_0 Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 338.0
TLS2_k127_5383238_1 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 289.0
TLS2_k127_5383238_2 Transcriptional regulator K07013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002272 258.0
TLS2_k127_5383238_3 photoreceptor activity - - - 0.00000000003276 72.0
TLS2_k127_5385532_0 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 610.0
TLS2_k127_5385532_1 COG1294 Cytochrome bd-type quinol oxidase subunit 2 K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 405.0
TLS2_k127_5385532_2 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006676 226.0
TLS2_k127_5388514_0 Aldose 1-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
TLS2_k127_5388514_1 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000002929 171.0
TLS2_k127_5389355_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 460.0
TLS2_k127_5404413_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 548.0
TLS2_k127_5404413_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 254.0
TLS2_k127_5404413_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000009999 147.0
TLS2_k127_5404413_3 ATPase, P-type transporting, HAD superfamily, subfamily IC K16905 - - 0.0000000000000000000000000000000002621 137.0
TLS2_k127_5404956_0 Doxx family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 328.0
TLS2_k127_5404956_1 Alpha beta hydrolase fold-3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 321.0
TLS2_k127_5404956_2 PFAM ribonuclease K07058 - - 0.00000000000000000000000000000000006425 138.0
TLS2_k127_5404956_3 - - - - 0.000000000000000000000000000003193 121.0
TLS2_k127_5404956_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000008442 98.0
TLS2_k127_5416895_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 577.0
TLS2_k127_5416895_1 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 527.0
TLS2_k127_5416895_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000002261 197.0
TLS2_k127_5416895_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000004817 180.0
TLS2_k127_5417341_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 611.0
TLS2_k127_5417341_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 489.0
TLS2_k127_5417341_2 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007371 286.0
TLS2_k127_5417341_3 Mandelate racemase muconate lactonizing enzyme, N-terminal domain K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 288.0
TLS2_k127_5417341_4 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000001072 246.0
TLS2_k127_5417341_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000007225 196.0
TLS2_k127_5417341_6 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000001397 165.0
TLS2_k127_5417341_7 LysR substrate binding domain K11921 - - 0.00000000000000000000000000000000004382 142.0
TLS2_k127_5417341_8 Oxidoreductase K10219 - 1.1.1.312 0.0000000000000000001097 100.0
TLS2_k127_5417341_9 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0001751 53.0
TLS2_k127_544386_0 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 366.0
TLS2_k127_544386_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002034 268.0
TLS2_k127_544386_2 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000001161 208.0
TLS2_k127_544386_3 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000006273 116.0
TLS2_k127_5444327_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 603.0
TLS2_k127_5444327_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 469.0
TLS2_k127_5444327_2 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 445.0
TLS2_k127_5444327_3 PFAM SMP-30 Gluconolaconase - - - 0.0000002623 60.0
TLS2_k127_5444329_0 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000001867 199.0
TLS2_k127_5444329_1 IMG reference gene - - - 0.00000000000000000000000000000005238 134.0
TLS2_k127_5450372_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.61e-214 676.0
TLS2_k127_5456167_0 Putative phage tail protein - - - 0.0 1262.0
TLS2_k127_5456167_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 588.0
TLS2_k127_5456167_10 - - - - 0.0000000000000000000000000000000002078 137.0
TLS2_k127_5456167_11 - - - - 0.0000000000000000000000000000000006374 133.0
TLS2_k127_5456167_12 - - - - 0.000000000000000000000000000001047 124.0
TLS2_k127_5456167_13 Conserved hypothetical protein 2217 (DUF2460) - - - 0.0000000000000000000000001132 110.0
TLS2_k127_5456167_14 - - - - 0.00000000000001544 83.0
TLS2_k127_5456167_15 - - - - 0.0000000000001637 75.0
TLS2_k127_5456167_2 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 559.0
TLS2_k127_5456167_3 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 522.0
TLS2_k127_5456167_4 P22 coat protein - gene protein 5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 471.0
TLS2_k127_5456167_5 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 434.0
TLS2_k127_5456167_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 404.0
TLS2_k127_5456167_7 teichoic acid transport K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 363.0
TLS2_k127_5456167_8 - - - - 0.00000000000000000000000000000000000000004507 162.0
TLS2_k127_5456167_9 - - - - 0.00000000000000000000000000000000000000006475 161.0
TLS2_k127_5456329_0 Carboxypeptidase regulatory-like domain - - - 0.0 1283.0
TLS2_k127_5456329_1 serine-type peptidase activity - - - 1.612e-205 648.0
TLS2_k127_5456329_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 573.0
TLS2_k127_5456329_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 572.0
TLS2_k127_5456329_4 AhpC TSA family K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001402 284.0
TLS2_k127_5459785_0 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 390.0
TLS2_k127_5459785_1 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 355.0
TLS2_k127_5459785_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003242 280.0
TLS2_k127_5459785_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000003754 197.0
TLS2_k127_5459785_4 - - - - 0.00001032 50.0
TLS2_k127_5461109_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.698e-213 672.0
TLS2_k127_5461109_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 413.0
TLS2_k127_5461109_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 370.0
TLS2_k127_5461109_3 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.00000000000000000000000000001964 122.0
TLS2_k127_5461109_4 Maltose acetyltransferase K00661 - 2.3.1.79 0.0000000000000000605 80.0
TLS2_k127_5462304_0 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 1.164e-196 619.0
TLS2_k127_5462304_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 612.0
TLS2_k127_5462304_2 acetyl-CoA hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 444.0
TLS2_k127_5462304_3 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 395.0
TLS2_k127_5462304_4 Citrate transporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 366.0
TLS2_k127_5462304_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 332.0
TLS2_k127_5462304_6 ThiS family K03636 - - 0.000000000000000000000000000000000005281 141.0
TLS2_k127_5462304_8 JAB/MPN domain - - - 0.00000000000000000002657 95.0
TLS2_k127_5463909_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 520.0
TLS2_k127_5463909_1 protocatechuate 3,4-dioxygenase activity - - - 0.000000001735 64.0
TLS2_k127_5475387_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.084e-232 726.0
TLS2_k127_5475387_1 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 441.0
TLS2_k127_5475387_2 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 355.0
TLS2_k127_5475387_3 Belongs to the peptidase S41A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 337.0
TLS2_k127_5475387_4 DinB family - - - 0.0000000000000000000000000000000001647 138.0
TLS2_k127_5484210_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 602.0
TLS2_k127_5484210_1 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 352.0
TLS2_k127_5484210_2 Belongs to the glycosyl hydrolase 2 family - - - 0.00000000000000000000000000000000000000000000000000000000000001575 220.0
TLS2_k127_5485063_0 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 350.0
TLS2_k127_5486239_0 Belongs to the radical SAM superfamily. PqqE family K06139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 576.0
TLS2_k127_5486239_1 Protein of unknown function (DUF4256) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 289.0
TLS2_k127_5486239_2 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007017 256.0
TLS2_k127_5486239_3 COG0662 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 252.0
TLS2_k127_5486239_4 Pfam:Pyridox_oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000007306 198.0
TLS2_k127_5486239_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000002791 184.0
TLS2_k127_5486239_6 Transcriptional regulator K07978 - - 0.000000000000000000000000000000000000000001545 162.0
TLS2_k127_5493028_0 surface antigen variable number - - - 3.062e-226 719.0
TLS2_k127_5493028_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 520.0
TLS2_k127_5493028_2 peptidyl-prolyl cis-trans isomerase activity K00645,K01802,K02597,K03769,K03770,K03771 - 2.3.1.39,5.2.1.8 0.00000000000000000000000000001073 130.0
TLS2_k127_5499359_0 Resolvase domain - - - 8.761e-290 905.0
TLS2_k127_5499359_1 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 354.0
TLS2_k127_5499359_2 transposase activity K07483,K07497 - - 0.000000000000000000000000000000000000000000000000000006396 191.0
TLS2_k127_5503818_0 transport - - - 0.0 1339.0
TLS2_k127_5503818_1 arylsulfatase activity K01137,K01138 - 3.1.6.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 529.0
TLS2_k127_5503818_2 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000000001934 124.0
TLS2_k127_5516964_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 429.0
TLS2_k127_5516964_1 IclR helix-turn-helix domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 375.0
TLS2_k127_5516964_2 Protein of unknown function (DUF1552) - - - 0.0000000000000000000000000000000000000000000000000000000000001128 216.0
TLS2_k127_553429_0 Carboxypeptidase regulatory-like domain - - - 0.0 1033.0
TLS2_k127_553429_1 Cytochrome c - - - 0.0 1024.0
TLS2_k127_553429_2 Protein of unknown function (DUF1501) - - - 7.967e-234 730.0
TLS2_k127_5538542_0 Domain of unknown function (DUF697) K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 449.0
TLS2_k127_5538542_1 Small GTP-binding protein domain protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 360.0
TLS2_k127_5539183_0 Histidine kinase K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001672 293.0
TLS2_k127_5539183_1 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000001091 204.0
TLS2_k127_5539183_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000000000000000000000000000000001028 183.0
TLS2_k127_5539183_3 - - - - 0.00000000000000000000000000000000008553 140.0
TLS2_k127_5539183_4 Transmembrane secretion effector - - - 0.0000000001759 63.0
TLS2_k127_5539183_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00002021 52.0
TLS2_k127_5541005_0 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000001154 215.0
TLS2_k127_5541005_1 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000001964 130.0
TLS2_k127_5541005_2 - - - - 0.000000000000000000000004265 112.0
TLS2_k127_5542296_0 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000002943 104.0
TLS2_k127_5542296_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000001716 90.0
TLS2_k127_5542296_2 Thiamine pyrophosphate enzyme, central domain K00156,K00158 - 1.2.3.3,1.2.5.1 0.000005543 51.0
TLS2_k127_5546766_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 455.0
TLS2_k127_5553991_0 Bacterial regulatory protein, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 504.0
TLS2_k127_5553991_1 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 484.0
TLS2_k127_5553991_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 452.0
TLS2_k127_5553991_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000008389 212.0
TLS2_k127_5553991_4 acr, cog1993 K09137 - - 0.0000000000000000000002344 101.0
TLS2_k127_5563113_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 517.0
TLS2_k127_5563113_1 8-amino-7-oxononanoate synthase activity K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 337.0
TLS2_k127_5563113_2 Trypsin-like serine protease - - - 0.00000007374 62.0
TLS2_k127_5567822_0 Carboxypeptidase regulatory-like domain - - - 0.0 1188.0
TLS2_k127_5567822_1 peptidyl-tyrosine sulfation - - - 2.092e-225 711.0
TLS2_k127_5567822_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 412.0
TLS2_k127_5567822_3 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 298.0
TLS2_k127_5567822_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004482 278.0
TLS2_k127_5567822_5 Glycosyl transferase, family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007274 254.0
TLS2_k127_5567822_6 PFAM secretion protein HlyD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007687 252.0
TLS2_k127_5567822_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000002814 144.0
TLS2_k127_5567822_8 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000006125 147.0
TLS2_k127_5567822_9 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000005997 139.0
TLS2_k127_5575554_0 protocatechuate 3,4-dioxygenase activity - - - 2.593e-295 947.0
TLS2_k127_5575554_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 524.0
TLS2_k127_5575554_2 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005308 273.0
TLS2_k127_5575554_3 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001233 274.0
TLS2_k127_5575554_4 TIGRFAM TonB family K03832 - - 0.0000000000000000000000000000000000000000000000002518 185.0
TLS2_k127_5575554_5 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000001519 166.0
TLS2_k127_5575554_6 PIN domain - - - 0.000000000000000000000000000003298 126.0
TLS2_k127_5575554_7 WD40-like Beta Propeller K03641 - - 0.0000000000162 69.0
TLS2_k127_5586043_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 465.0
TLS2_k127_5586043_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000942 162.0
TLS2_k127_5586043_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000004097 109.0
TLS2_k127_5586043_3 Belongs to the ATPase B chain family K02109 - - 0.000000000000000000003181 99.0
TLS2_k127_5596922_0 AcrB/AcrD/AcrF family - - - 0.0 1327.0
TLS2_k127_5596922_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 505.0
TLS2_k127_5596922_2 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 396.0
TLS2_k127_5596922_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 362.0
TLS2_k127_5596922_4 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 355.0
TLS2_k127_5596922_5 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000002487 257.0
TLS2_k127_5596922_6 ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000003473 207.0
TLS2_k127_5600113_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 548.0
TLS2_k127_5600113_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 334.0
TLS2_k127_5600113_2 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 301.0
TLS2_k127_5600113_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 302.0
TLS2_k127_5600113_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000008511 200.0
TLS2_k127_5600113_5 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000001582 185.0
TLS2_k127_5600517_0 Carboxypeptidase regulatory-like domain - - - 0.0 1804.0
TLS2_k127_5600517_1 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 6.645e-200 629.0
TLS2_k127_5600517_2 TIR domain - - - 0.000000000003144 78.0
TLS2_k127_5608127_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 599.0
TLS2_k127_5608127_1 MlrC C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 479.0
TLS2_k127_5608127_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000009552 138.0
TLS2_k127_5616178_0 Sulfate permease family K03321 - - 5.85e-226 716.0
TLS2_k127_5616178_1 AcrB/AcrD/AcrF family K15726 - - 0.000000000000000000000000000000000000000000000000000000000000009439 218.0
TLS2_k127_5616178_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000001587 213.0
TLS2_k127_5616178_3 Protein of unknown function (DUF2490) - - - 0.000000000000000000000000000000000000000000000007044 182.0
TLS2_k127_5616178_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000009625 153.0
TLS2_k127_5616178_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000212 131.0
TLS2_k127_5616178_6 - - - - 0.0000000000000000000001212 100.0
TLS2_k127_5620833_0 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 345.0
TLS2_k127_5620833_1 PFAM Bacterial Ig-like domain (group 2) - - - 0.0000000001151 65.0
TLS2_k127_5621378_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 406.0
TLS2_k127_5660605_0 Sodium:sulfate symporter transmembrane region K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 578.0
TLS2_k127_5660605_1 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
TLS2_k127_5660605_2 Arylsulfotransferase Ig-like domain K01023 - 2.8.2.22 0.00000000000000000000000000000000004838 153.0
TLS2_k127_5660605_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000004137 98.0
TLS2_k127_5660605_4 Sodium:sulfate symporter transmembrane region K03319 - - 0.0000004773 57.0
TLS2_k127_5661154_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 308.0
TLS2_k127_5661154_1 - - - - 0.0000000000000000000000000000000000000000000000000006612 187.0
TLS2_k127_5661154_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000004214 147.0
TLS2_k127_5661154_3 - - - - 0.000000000000000000000000000000000001276 144.0
TLS2_k127_5661154_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000001782 142.0
TLS2_k127_5662484_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 493.0
TLS2_k127_5662484_1 - - - - 0.000000000000000002809 87.0
TLS2_k127_5662484_2 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000003866 83.0
TLS2_k127_5662484_3 - - - - 0.0000000000000006931 85.0
TLS2_k127_5662484_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000003279 61.0
TLS2_k127_5666994_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 434.0
TLS2_k127_5666994_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 281.0
TLS2_k127_566819_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006488 253.0
TLS2_k127_566819_1 - - - - 0.00000000000000000000000000000000000000001941 165.0
TLS2_k127_566819_3 Integrase core domain - - - 0.00000000493 62.0
TLS2_k127_5669302_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 458.0
TLS2_k127_5669302_1 Glutamine--fructose-6-phosphate aminotransferase isomerizing K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 437.0
TLS2_k127_5669302_12 UPF0391 membrane protein - - - 0.0000008214 53.0
TLS2_k127_5669302_2 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 367.0
TLS2_k127_5669302_3 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 369.0
TLS2_k127_5669302_4 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 317.0
TLS2_k127_5669302_5 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 307.0
TLS2_k127_5669302_6 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003284 251.0
TLS2_k127_5669302_7 - - - - 0.00000000000000000000000000000000000000000000000000008736 197.0
TLS2_k127_5669302_8 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000000000000000000002447 172.0
TLS2_k127_5669302_9 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000004613 125.0
TLS2_k127_5674129_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 567.0
TLS2_k127_5674129_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 297.0
TLS2_k127_5674129_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
TLS2_k127_5674129_3 Trehalose utilisation - - - 0.000000000000000000000000000001517 122.0
TLS2_k127_5674129_4 COGs COG5499 transcription regulator containing HTH domain K18831 - - 0.000000000000000001396 91.0
TLS2_k127_5683141_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 421.0
TLS2_k127_5683141_1 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 386.0
TLS2_k127_5683141_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 331.0
TLS2_k127_5683141_3 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 322.0
TLS2_k127_5683141_4 RepB DNA-primase from phage plasmid - - - 0.00000000000000000000005466 111.0
TLS2_k127_5683141_5 iron dependent repressor - - - 0.00000008158 60.0
TLS2_k127_5685999_0 D-alanine [D-alanyl carrier protein] ligase activity - - - 1.559e-284 898.0
TLS2_k127_5685999_1 secreted protein-putative xanthan lyase related - - - 7.826e-273 852.0
TLS2_k127_5685999_2 succinate dehydrogenase - - - 3.788e-267 836.0
TLS2_k127_5685999_3 Carboxypeptidase regulatory-like domain - - - 1.58e-258 836.0
TLS2_k127_5685999_4 Protein of unknown function (DUF1552) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 583.0
TLS2_k127_5685999_5 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 494.0
TLS2_k127_5685999_6 Domain of unknown function (DUF2382) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 269.0
TLS2_k127_5685999_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0001478 53.0
TLS2_k127_568677_0 similarity to GP 3192745 - - - 3.516e-215 676.0
TLS2_k127_568677_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000007426 210.0
TLS2_k127_568677_2 periplasmic or secreted lipoprotein K04065 - - 0.00000000000000000002431 101.0
TLS2_k127_568677_3 - - - - 0.000000000000008905 76.0
TLS2_k127_568677_4 Entericidin EcnA/B family - - - 0.000000002364 64.0
TLS2_k127_5689150_0 Fumarylacetoacetase N-terminal K01555 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 374.0
TLS2_k127_5689150_1 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 288.0
TLS2_k127_5689150_2 phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000002483 158.0
TLS2_k127_5689150_3 Outer membrane receptor - - - 0.00001508 51.0
TLS2_k127_5692884_0 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 473.0
TLS2_k127_5692884_1 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 421.0
TLS2_k127_5692884_2 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 326.0
TLS2_k127_5692884_3 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000000002568 192.0
TLS2_k127_5692884_4 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000008698 104.0
TLS2_k127_5692884_5 Carbonyl reductase K11539 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006066,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008753,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016137,GO:0016491,GO:0016614,GO:0016616,GO:0016651,GO:0016655,GO:0016999,GO:0017144,GO:0019748,GO:0019752,GO:0022607,GO:0030638,GO:0030647,GO:0031974,GO:0032787,GO:0032991,GO:0034308,GO:0036094,GO:0042180,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044597,GO:0044598,GO:0046394,GO:0047025,GO:0048037,GO:0048038,GO:0050661,GO:0050662,GO:0051186,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051290,GO:0051291,GO:0055114,GO:0065003,GO:0070013,GO:0070402,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:0097164,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1901615,GO:1901657,GO:1901661,GO:1902494,GO:1902644,GO:1990204 - 0.0000000000000001243 89.0
TLS2_k127_5692884_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.000000000000001358 85.0
TLS2_k127_5695376_0 PQQ enzyme repeat K00117 - 1.1.5.2 1.577e-315 984.0
TLS2_k127_5695376_1 FtsZ-dependent cytokinesis K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004183 267.0
TLS2_k127_5695376_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000003422 256.0
TLS2_k127_5695376_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003222 243.0
TLS2_k127_5695376_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000002136 181.0
TLS2_k127_5703711_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 599.0
TLS2_k127_5714000_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1789.0
TLS2_k127_5714000_1 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001991 203.0
TLS2_k127_5714548_0 PFAM Aldehyde dehydrogenase K00128 - 1.2.1.3 6.962e-207 655.0
TLS2_k127_5714548_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 318.0
TLS2_k127_5714548_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000009336 229.0
TLS2_k127_5714548_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000002845 193.0
TLS2_k127_5716200_0 - - - - 0.000000000000000000000000000000000000000000003188 169.0
TLS2_k127_5718076_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000001917 181.0
TLS2_k127_5718076_1 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000003105 175.0
TLS2_k127_5718076_2 Acetyl-CoA carboxylase, central region - - - 0.0000000000000000000000000000000002361 135.0
TLS2_k127_5718481_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 391.0
TLS2_k127_5718481_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 341.0
TLS2_k127_5718481_2 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004886 276.0
TLS2_k127_5718481_3 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000004833 181.0
TLS2_k127_5718481_4 - - - - 0.000000000000000000000000003264 117.0
TLS2_k127_572611_0 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000001726 158.0
TLS2_k127_5728749_0 TonB-dependent receptor - - - 1.684e-280 890.0
TLS2_k127_5728749_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000002219 242.0
TLS2_k127_5739278_0 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 496.0
TLS2_k127_5739278_1 HipA N-terminal domain K07154 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 317.0
TLS2_k127_5739278_2 CHAT domain - - - 0.00000000000000000000000000000000000000000000511 187.0
TLS2_k127_5741181_0 Protein of unknown function (DUF1501) - - - 1.813e-236 740.0
TLS2_k127_5741181_1 Cytochrome c - - - 0.00000000000000000000000000000000000001195 148.0
TLS2_k127_574539_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 524.0
TLS2_k127_574539_1 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 432.0
TLS2_k127_574539_2 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000005153 104.0
TLS2_k127_574539_3 - - - - 0.00000000000000000001342 93.0
TLS2_k127_574539_4 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000006026 75.0
TLS2_k127_574539_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000003503 63.0
TLS2_k127_5752118_0 Ankyrin repeat - - - 2.555e-232 729.0
TLS2_k127_5752118_1 Resolvase, N terminal domain - - - 0.00000000000000000000003728 104.0
TLS2_k127_575387_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 3.863e-194 618.0
TLS2_k127_575387_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 354.0
TLS2_k127_575387_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 331.0
TLS2_k127_5763108_0 lipid-A-disaccharide synthase activity K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 438.0
TLS2_k127_5763108_1 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000002831 172.0
TLS2_k127_5763108_2 Cytidylyltransferase - - - 0.00000000000000000005248 103.0
TLS2_k127_5763108_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000008397 64.0
TLS2_k127_5765532_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
TLS2_k127_5765532_1 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 306.0
TLS2_k127_5765532_2 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000001759 224.0
TLS2_k127_5765532_3 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000004292 216.0
TLS2_k127_5765532_4 Phosphate transporter family K03306 - - 0.00000000000000000000000000000002217 128.0
TLS2_k127_5786543_0 Putative transposase - - - 5.734e-194 612.0
TLS2_k127_5786543_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 421.0
TLS2_k127_5786543_2 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000684 218.0
TLS2_k127_5786543_3 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000001999 142.0
TLS2_k127_5793488_0 - - - - 0.0000000000000000000000000000000000001264 149.0
TLS2_k127_5793488_1 Putative cyclase - - - 0.0000000000000000000000004391 111.0
TLS2_k127_5793488_2 Belongs to the ompA family K03286 - - 0.0000000000000000003122 98.0
TLS2_k127_5793488_3 PFAM SMP-30 Gluconolaconase - - - 0.0000002286 63.0
TLS2_k127_5805979_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.052e-296 920.0
TLS2_k127_5805979_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 598.0
TLS2_k127_5805979_2 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 415.0
TLS2_k127_5805979_3 ATP-dependent DNA helicase activity K01144,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005823 282.0
TLS2_k127_5805979_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002988 261.0
TLS2_k127_5805979_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000006474 235.0
TLS2_k127_5805979_6 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000002559 144.0
TLS2_k127_5805979_8 Tetratricopeptide repeat - - - 0.000000001526 70.0
TLS2_k127_5805979_9 - - - - 0.0000003092 61.0
TLS2_k127_5808996_0 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 573.0
TLS2_k127_5808996_1 COG3119 Arylsulfatase A K01132 - 3.1.6.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 440.0
TLS2_k127_5808996_3 hydrolase activity, acting on ester bonds K22369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 385.0
TLS2_k127_5808996_4 ribonuclease inhibitor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000006103 231.0
TLS2_k127_5808996_5 - - - - 0.0000000000000000000000000000000000000004017 153.0
TLS2_k127_5811439_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.167e-205 645.0
TLS2_k127_5811439_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 450.0
TLS2_k127_5811439_2 Dehydrogenase E1 component K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 331.0
TLS2_k127_5811439_3 - K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006617 257.0
TLS2_k127_5811439_4 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000002748 174.0
TLS2_k127_5821381_0 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000004842 256.0
TLS2_k127_5821381_1 PFAM intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000002218 226.0
TLS2_k127_5821381_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000001031 193.0
TLS2_k127_5825071_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000009006 282.0
TLS2_k127_5825071_1 cAMP biosynthetic process K03641 - - 0.0000000008175 72.0
TLS2_k127_5828199_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 435.0
TLS2_k127_5828199_1 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 285.0
TLS2_k127_5828199_2 PepSY-associated TM region - - - 0.0000000000000000000000005813 108.0
TLS2_k127_5833701_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 357.0
TLS2_k127_5833701_1 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008919 278.0
TLS2_k127_5833701_2 Iron-regulated membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000245 263.0
TLS2_k127_5839890_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 612.0
TLS2_k127_5839890_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 383.0
TLS2_k127_5839890_10 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000000000002274 160.0
TLS2_k127_5839890_11 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000000000000000000000000002863 166.0
TLS2_k127_5839890_12 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000007155 134.0
TLS2_k127_5839890_14 PFAM flagellar FlbD family protein K02385 - - 0.0000000000000002334 80.0
TLS2_k127_5839890_2 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 324.0
TLS2_k127_5839890_3 flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 291.0
TLS2_k127_5839890_4 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006707 265.0
TLS2_k127_5839890_5 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 254.0
TLS2_k127_5839890_6 PFAM OmpA K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000001377 245.0
TLS2_k127_5839890_7 flagellar basal-body rod protein FlgC K02388 - - 0.0000000000000000000000000000000000000000000000000000002704 196.0
TLS2_k127_5839890_8 Bacterial flagellin N-terminal helical region K02397 - - 0.000000000000000000000000000000000000000000000000000005715 201.0
TLS2_k127_5839890_9 SRP54-type protein, GTPase domain K02404 - - 0.0000000000000000000000000000000000000000000000000003935 198.0
TLS2_k127_5843702_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 569.0
TLS2_k127_5843702_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 531.0
TLS2_k127_5843702_2 Monooxygenase fad-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 399.0
TLS2_k127_5843702_3 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 371.0
TLS2_k127_5843702_4 R3H domain K06346 - - 0.00000000000000000000000000000000000000000000000000000000004129 211.0
TLS2_k127_5843702_5 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000002109 152.0
TLS2_k127_5843702_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000001833 105.0
TLS2_k127_5843702_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000001129 87.0
TLS2_k127_5843702_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000001301 80.0
TLS2_k127_5847609_0 peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 366.0
TLS2_k127_5847609_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 311.0
TLS2_k127_5848686_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1325.0
TLS2_k127_5848686_1 PFAM Response regulator receiver domain - - - 1.03e-206 652.0
TLS2_k127_5848686_2 HlyD family secretion protein K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 349.0
TLS2_k127_5848686_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 346.0
TLS2_k127_5848686_4 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 331.0
TLS2_k127_5848686_5 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 319.0
TLS2_k127_5848686_6 COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009412 263.0
TLS2_k127_5848686_7 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000118 267.0
TLS2_k127_5848686_8 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000002966 250.0
TLS2_k127_5848686_9 COG3039 Transposase and inactivated derivatives IS5 family K07481 - - 0.000000000000000004742 95.0
TLS2_k127_5848927_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 601.0
TLS2_k127_5848927_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000129 283.0
TLS2_k127_5848927_3 domain, Protein - - - 0.00000000000000000000000000000000007303 153.0
TLS2_k127_5848927_4 - - - - 0.0000000000000000000000000001294 119.0
TLS2_k127_5855841_0 Alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 436.0
TLS2_k127_5855841_1 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003056 261.0
TLS2_k127_5860045_0 Belongs to the MIP aquaporin (TC 1.A.8) family K02440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 353.0
TLS2_k127_5860045_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 348.0
TLS2_k127_5860969_0 PFAM carbohydrate kinase K00853 - 2.7.1.16 2.247e-233 728.0
TLS2_k127_5860969_1 Domain of unknown function (DUF5060) - - - 0.000001357 52.0
TLS2_k127_5867600_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 370.0
TLS2_k127_5867600_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 362.0
TLS2_k127_5867600_2 domain, Protein K13874,K22217 - 3.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000003638 284.0
TLS2_k127_5869217_0 Acyl transferase domain - - - 1.09e-249 784.0
TLS2_k127_5878174_0 PFAM FAD linked oxidase K00594 - 1.1.3.41 5.317e-199 629.0
TLS2_k127_5878174_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 335.0
TLS2_k127_5878633_0 Carboxypeptidase regulatory-like domain - - - 1.5e-323 1001.0
TLS2_k127_5879027_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1004.0
TLS2_k127_5879027_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890,K06878 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 451.0
TLS2_k127_5880746_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 401.0
TLS2_k127_5880746_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 329.0
TLS2_k127_588220_0 recombinase activity - - - 1.177e-292 904.0
TLS2_k127_588220_1 COG1484 DNA replication protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001865 226.0
TLS2_k127_588220_2 DNA invertase Pin - - - 0.0000001509 57.0
TLS2_k127_5883044_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 542.0
TLS2_k127_5883044_1 aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 347.0
TLS2_k127_5883044_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000002992 213.0
TLS2_k127_5883044_3 - - - - 0.000000000000000000001488 95.0
TLS2_k127_5883044_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000001515 94.0
TLS2_k127_5887391_0 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004825 284.0
TLS2_k127_5887391_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000812 214.0
TLS2_k127_5887391_2 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000000000000003173 165.0
TLS2_k127_5887391_3 FMN binding - - - 0.000000000000000000000000000000000000000002928 160.0
TLS2_k127_5890467_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 6.279e-292 914.0
TLS2_k127_5890467_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 420.0
TLS2_k127_5890467_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 412.0
TLS2_k127_5890467_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 383.0
TLS2_k127_5890467_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000001843 177.0
TLS2_k127_5890467_5 Domain of unknown function (DUF4142) - - - 0.00000000000000000000001765 111.0
TLS2_k127_5893958_0 efflux protein, MATE family K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 370.0
TLS2_k127_5893958_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.00001302 52.0
TLS2_k127_5895285_0 DEAD DEAH box K03724 - - 6.42e-308 964.0
TLS2_k127_5895285_1 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 604.0
TLS2_k127_5895285_2 nucleic acid phosphodiester bond hydrolysis K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 399.0
TLS2_k127_5895285_3 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006339 254.0
TLS2_k127_5895285_4 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000002043 194.0
TLS2_k127_5904510_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000001937 180.0
TLS2_k127_5904510_1 alginic acid biosynthetic process K01729 - 4.2.2.3 0.0000000000000000000000000000000001236 143.0
TLS2_k127_5904510_3 AcrB/AcrD/AcrF family - - - 0.0000000000002963 77.0
TLS2_k127_5904510_4 - - - - 0.000002069 58.0
TLS2_k127_590683_0 Carboxypeptidase regulatory-like domain - - - 0.0 1444.0
TLS2_k127_590683_1 Carboxypeptidase regulatory-like domain - - - 1.244e-252 820.0
TLS2_k127_590683_2 PFAM TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 372.0
TLS2_k127_591071_0 peptidase dimerisation domain - - - 3.802e-201 640.0
TLS2_k127_591071_1 Fumarase C C-terminus K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 587.0
TLS2_k127_591071_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000133 102.0
TLS2_k127_592681_0 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000002369 192.0
TLS2_k127_592681_1 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000139 190.0
TLS2_k127_592681_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000002271 152.0
TLS2_k127_5930704_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 608.0
TLS2_k127_5930704_2 Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 359.0
TLS2_k127_5930704_3 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002528 270.0
TLS2_k127_5930704_4 Membrane - - - 0.000000000000000000000000000000000000000000000000003347 188.0
TLS2_k127_5930704_5 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000001002 175.0
TLS2_k127_5930704_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair - - - 0.000000000000000000000000000000000000000000006896 173.0
TLS2_k127_5930704_7 EVE domain - - - 0.000000000000000000000000000000000000007979 149.0
TLS2_k127_5930704_8 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000005811 70.0
TLS2_k127_5930704_9 TIGRFAM LPXTG-motif cell wall anchor domain - - - 0.000001919 58.0
TLS2_k127_5934742_0 nitrite transmembrane transporter activity - - - 0.0 1023.0
TLS2_k127_5934742_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 368.0
TLS2_k127_5934742_2 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000002721 211.0
TLS2_k127_5935771_0 peptidase K01278 - 3.4.14.5 2.598e-224 718.0
TLS2_k127_5935771_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000002357 166.0
TLS2_k127_5935771_2 NUDIX domain K03574 - 3.6.1.55 0.0002817 44.0
TLS2_k127_5947175_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 416.0
TLS2_k127_5947175_1 Oxidoreductase family, NAD-binding Rossmann fold K00118,K13020 - 1.1.1.335,1.1.99.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 317.0
TLS2_k127_5947175_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 304.0
TLS2_k127_5947175_3 Glycosyl transferase 4-like domain - - - 0.000000000008733 70.0
TLS2_k127_5947175_4 self proteolysis - - - 0.0000000003521 70.0
TLS2_k127_5947175_5 YD repeat (two copies) - - - 0.0002909 51.0
TLS2_k127_5950228_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.043e-246 773.0
TLS2_k127_5950228_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 7.274e-244 767.0
TLS2_k127_5950228_2 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 465.0
TLS2_k127_5950228_3 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 380.0
TLS2_k127_5950228_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000001544 187.0
TLS2_k127_5950228_5 OsmC-like protein - - - 0.0000000000000000000000000000000000000000008244 161.0
TLS2_k127_5956452_0 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000003018 209.0
TLS2_k127_5956452_1 Integrase core domain - - - 0.00000000000000000001465 96.0
TLS2_k127_5956452_2 Integrase - - - 0.0000003193 53.0
TLS2_k127_5965491_0 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 408.0
TLS2_k127_5965491_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001137 211.0
TLS2_k127_5971224_0 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000003653 242.0
TLS2_k127_5971224_1 Biotin-requiring enzyme - - - 0.0000000000000000000007121 98.0
TLS2_k127_5987185_0 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000002114 200.0
TLS2_k127_5987185_1 Radical SAM superfamily K06871 - - 0.0000000000000000000000000000000000000000000000000000003207 196.0
TLS2_k127_5987185_2 Transcriptional regulator - - - 0.0000000000000000000002154 102.0
TLS2_k127_5987185_3 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000002402 95.0
TLS2_k127_5991119_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000004301 166.0
TLS2_k127_5991119_1 Glycosyltransferase like family 2 K16555 - - 0.000000000000000000000000000000000000003436 159.0
TLS2_k127_5991119_2 Oligosaccharide biosynthesis protein Alg14 like - - - 0.00000000000000000000000000000000000007276 147.0
TLS2_k127_5991119_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000001115 154.0
TLS2_k127_5991119_4 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000004826 140.0
TLS2_k127_5991119_5 asparagine synthase - - - 0.00000000000000000000000002343 124.0
TLS2_k127_5991119_6 PFAM O-Antigen - - - 0.00009374 51.0
TLS2_k127_5992685_0 Erythromycin esterase K06880 - - 0.00000000000000000000000000000000000002613 160.0
TLS2_k127_5992685_1 - - - - 0.0000000002673 68.0
TLS2_k127_5992685_2 cAMP biosynthetic process K03641 - - 0.000001698 59.0
TLS2_k127_6016185_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.352e-210 663.0
TLS2_k127_6016185_1 alpha beta - - - 1.671e-198 635.0
TLS2_k127_6016185_2 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008263 274.0
TLS2_k127_6016185_3 protein import - - - 0.000000000000000000000001928 115.0
TLS2_k127_6018082_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 586.0
TLS2_k127_6018082_1 Belongs to the GSP D family K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 588.0
TLS2_k127_6018082_2 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 407.0
TLS2_k127_6018082_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 326.0
TLS2_k127_6018082_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000001482 202.0
TLS2_k127_6021965_0 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 545.0
TLS2_k127_6021965_1 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 376.0
TLS2_k127_6021965_2 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000006051 236.0
TLS2_k127_6034247_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K02482 - 2.7.13.3 8.871e-242 766.0
TLS2_k127_6034247_1 cheY-homologous receiver domain - - - 0.000000000000000000000000009675 115.0
TLS2_k127_6035983_0 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000007561 197.0
TLS2_k127_6035983_1 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000000000000001883 159.0
TLS2_k127_6035983_2 - - - - 0.000000000000007241 79.0
TLS2_k127_6044716_0 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000001122 239.0
TLS2_k127_6044716_1 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0000000000000000000000000000000000000000000000001526 181.0
TLS2_k127_6044716_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000002867 168.0
TLS2_k127_6061329_0 Phospholipase/Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
TLS2_k127_6061329_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000009423 256.0
TLS2_k127_6061329_2 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000004018 143.0
TLS2_k127_6070659_0 Collagenase K08303 - - 0.0 1101.0
TLS2_k127_6070659_1 Alkaline phosphatase K01113 - 3.1.3.1 1.937e-197 628.0
TLS2_k127_6070659_2 glyoxalase bleomycin resistance protein K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000723 253.0
TLS2_k127_6070659_3 - - - - 0.000000000000000000000000000000000001503 149.0
TLS2_k127_6070659_4 NUDIX domain K03574 - 3.6.1.55 0.00000000000004452 81.0
TLS2_k127_6070659_5 - - - - 0.00000000003479 70.0
TLS2_k127_6072651_0 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 535.0
TLS2_k127_6076436_0 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 497.0
TLS2_k127_6076436_1 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 427.0
TLS2_k127_6106436_0 Belongs to the glycosyl hydrolase 30 family K01181,K15921,K15924 - 3.2.1.136,3.2.1.55,3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 572.0
TLS2_k127_6106436_1 ABC transporter, transmembrane K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 446.0
TLS2_k127_6106436_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 427.0
TLS2_k127_6107142_0 PFAM transposase Tn3 family protein - - - 5.664e-205 669.0
TLS2_k127_611499_0 protein import - - - 0.00000000000000000000000000000000000000000000000000000000000000000001424 251.0
TLS2_k127_611499_1 response regulator K02479,K07684,K07685 - - 0.000000000000000000000000000000000001766 149.0
TLS2_k127_6126926_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 492.0
TLS2_k127_6126926_1 metallopeptidase activity K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 301.0
TLS2_k127_6126926_2 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 278.0
TLS2_k127_6126926_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000004318 261.0
TLS2_k127_6126926_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000006061 133.0
TLS2_k127_6126926_5 Beta-lactamase - - - 0.000000002139 63.0
TLS2_k127_6128350_0 Amino acid permease - - - 0.0 1043.0
TLS2_k127_6128350_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 492.0
TLS2_k127_6128350_2 - - - - 0.0000000003885 65.0
TLS2_k127_6130831_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000001476 211.0
TLS2_k127_6130831_1 peptidyl-tyrosine sulfation - - - 0.0002084 52.0
TLS2_k127_6132259_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1172.0
TLS2_k127_6132259_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 590.0
TLS2_k127_6132259_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002137 261.0
TLS2_k127_6132259_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001352 243.0
TLS2_k127_6132259_4 PPR repeat - - - 0.000000000006939 76.0
TLS2_k127_6132259_5 Belongs to the arylamine N-acetyltransferase family - - - 0.0005491 44.0
TLS2_k127_6136261_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
TLS2_k127_6136261_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000008039 206.0
TLS2_k127_6136585_0 Peptidase M14, carboxypeptidase A - - - 2.017e-299 935.0
TLS2_k127_6136585_1 - - - - 0.0000000000000000000002658 102.0
TLS2_k127_6137091_0 Cytochrome c - - - 9.007e-208 676.0
TLS2_k127_6137091_1 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 285.0
TLS2_k127_6137091_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000009177 227.0
TLS2_k127_6137091_3 RES - - - 0.00000000000000000009619 95.0
TLS2_k127_6137091_4 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K03692 - 2.4.1.213 0.0000000000000000611 81.0
TLS2_k127_6137525_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.0 1148.0
TLS2_k127_6137525_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.035e-255 799.0
TLS2_k127_6137525_10 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000002725 179.0
TLS2_k127_6137525_11 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000007999 121.0
TLS2_k127_6137525_12 PFAM ribonuclease K07058 - - 0.000000000000000000000003974 106.0
TLS2_k127_6137525_13 DinB family - - - 0.0000000000000000008784 93.0
TLS2_k127_6137525_14 - - - - 0.000000000004861 68.0
TLS2_k127_6137525_2 Psort location CytoplasmicMembrane, score - - - 1.107e-215 693.0
TLS2_k127_6137525_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 563.0
TLS2_k127_6137525_4 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 537.0
TLS2_k127_6137525_5 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 467.0
TLS2_k127_6137525_6 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 432.0
TLS2_k127_6137525_7 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 404.0
TLS2_k127_6137525_8 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000000000000000000000000000001493 207.0
TLS2_k127_6142240_0 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 532.0
TLS2_k127_6142240_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 511.0
TLS2_k127_6142240_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 289.0
TLS2_k127_6142240_3 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004419 271.0
TLS2_k127_6142240_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002536 245.0
TLS2_k127_6142240_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000002372 221.0
TLS2_k127_6142367_0 DNA topological change K03168 - 5.99.1.2 0.0 1090.0
TLS2_k127_6142367_1 long-chain fatty acid transporting porin activity K09806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 366.0
TLS2_k127_6142367_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.00000000000000000000000000000000000000000000007855 170.0
TLS2_k127_6143567_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 516.0
TLS2_k127_6143567_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 310.0
TLS2_k127_6143567_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000001867 224.0
TLS2_k127_6143577_0 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 372.0
TLS2_k127_6143577_1 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 366.0
TLS2_k127_6143577_2 PFAM YdjC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 330.0
TLS2_k127_6143577_3 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 320.0
TLS2_k127_6143577_4 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000007966 199.0
TLS2_k127_614939_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 436.0
TLS2_k127_614939_1 Putative sugar-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 364.0
TLS2_k127_614939_2 ATPases associated with a variety of cellular activities K02056,K10441,K10542,K10545,K10551,K10562,K17204,K17210 - 3.6.3.17 0.0000000000000000000000000000000000000193 151.0
TLS2_k127_614939_3 Predicted periplasmic lipoprotein (DUF2291) - - - 0.000000000000000000000000001552 120.0
TLS2_k127_6149916_0 CBD_II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006565 279.0
TLS2_k127_6149916_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000004201 178.0
TLS2_k127_6157821_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 537.0
TLS2_k127_6157821_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000005534 261.0
TLS2_k127_6157821_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005134 239.0
TLS2_k127_6157821_3 Acid phosphatase - - - 0.00000000000000000000000000000000000000000000000000000378 200.0
TLS2_k127_6157821_4 beta-lactamase K17838,K19211,K21277 - 3.5.2.6 0.0000000000000000000000000000000000000000458 174.0
TLS2_k127_6157821_5 - - - - 0.00000000000000000000000000000004422 128.0
TLS2_k127_6157821_6 PFAM CHAD domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000001071 58.0
TLS2_k127_6157821_7 CHAD domain - - - 0.0000147 54.0
TLS2_k127_6162196_0 - - - - 1.154e-247 780.0
TLS2_k127_6162196_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00700 - 2.4.1.18 1.228e-200 639.0
TLS2_k127_6162196_2 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 395.0
TLS2_k127_6173144_0 Carboxypeptidase regulatory-like domain - - - 0.0 1456.0
TLS2_k127_6173144_1 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000004801 201.0
TLS2_k127_6173144_2 carboxylic acid catabolic process K01684 - 4.2.1.6 0.000000000006946 72.0
TLS2_k127_6174125_0 Putative glucoamylase - - - 1.57e-214 694.0
TLS2_k127_6185289_0 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 374.0
TLS2_k127_6185289_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006174 284.0
TLS2_k127_6185289_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003161 287.0
TLS2_k127_6185289_3 synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000007115 240.0
TLS2_k127_6185289_4 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000004186 145.0
TLS2_k127_6185289_6 - - - - 0.000000000000000000000000000000004944 136.0
TLS2_k127_6185289_7 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.000000000000001006 81.0
TLS2_k127_6189046_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ - - - 1.732e-273 845.0
TLS2_k127_6189046_1 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001274 216.0
TLS2_k127_6189046_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001125 137.0
TLS2_k127_6189046_3 membrane K08978 - - 0.00000000000000000000001185 104.0
TLS2_k127_6189046_4 membrane - - - 0.000000000000000000004523 98.0
TLS2_k127_6189046_5 - - - - 0.00000000000000000005568 89.0
TLS2_k127_6189046_6 - - - - 0.00002435 51.0
TLS2_k127_619142_0 TonB-dependent receptor - - - 0.0 1079.0
TLS2_k127_619142_1 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 370.0
TLS2_k127_619142_10 - - - - 0.00000000000000000002464 98.0
TLS2_k127_619142_11 - - - - 0.000000000002138 76.0
TLS2_k127_619142_12 acyl transferase domain - - - 0.0000000000108 65.0
TLS2_k127_619142_2 histidine kinase dimerisation and phosphoacceptor region K11617 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 368.0
TLS2_k127_619142_3 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001453 271.0
TLS2_k127_619142_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000007441 255.0
TLS2_k127_619142_5 Protein of unknown function (DUF4038) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002329 261.0
TLS2_k127_619142_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000191 239.0
TLS2_k127_619142_7 polysaccharide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000005179 205.0
TLS2_k127_619142_8 AraC-like ligand binding domain - - - 0.0000000000000000000000000006146 126.0
TLS2_k127_619142_9 - - - - 0.000000000000000000000112 109.0
TLS2_k127_61935_2 - - - - 0.00000000000000001755 94.0
TLS2_k127_61935_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000001101 64.0
TLS2_k127_6193913_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 259.0
TLS2_k127_6193913_1 Dioxygenase K00449 - 1.13.11.3 0.00000000000000000000000000000002172 132.0
TLS2_k127_6193913_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000005179 100.0
TLS2_k127_6195890_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 310.0
TLS2_k127_6195890_1 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000000000000000007983 147.0
TLS2_k127_6195890_2 Protein of unknown function (DUF1549) - - - 0.0000000000000000000000000000007483 130.0
TLS2_k127_619842_0 TonB-dependent receptor - - - 0.0 1118.0
TLS2_k127_619842_1 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 421.0
TLS2_k127_619842_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000007253 144.0
TLS2_k127_619842_3 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000006582 137.0
TLS2_k127_619842_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000234 109.0
TLS2_k127_619880_0 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000005244 216.0
TLS2_k127_619880_1 transport - - - 0.00000000000000000000000000000000008528 144.0
TLS2_k127_6200113_0 TonB-dependent receptor - - - 0.0 1274.0
TLS2_k127_6200113_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001143 259.0
TLS2_k127_6200113_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000007781 233.0
TLS2_k127_6200113_3 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.000000000000000000000000000000000000000000001743 167.0
TLS2_k127_6204408_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 334.0
TLS2_k127_6204408_1 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000002531 188.0
TLS2_k127_6208964_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000003026 213.0
TLS2_k127_6208964_1 response regulator - - - 0.000000000000000000000000000000000000000000000009227 179.0
TLS2_k127_6208964_2 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000003804 146.0
TLS2_k127_6208964_3 addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000000463 139.0
TLS2_k127_6208964_4 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000002803 123.0
TLS2_k127_6208964_5 TIGRFAM amino acid adenylation domain - - - 0.000007264 52.0
TLS2_k127_621081_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 446.0
TLS2_k127_621081_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 378.0
TLS2_k127_621081_2 Sulfatase - - - 0.00000000000000000000183 99.0
TLS2_k127_6211867_0 BNR repeat-like domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 508.0
TLS2_k127_6211867_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 438.0
TLS2_k127_6211867_2 - - - - 0.00000000000000000000000000000000000000002287 157.0
TLS2_k127_6211867_3 - - - - 0.00000000000000000000000001809 117.0
TLS2_k127_6211867_4 BNR repeat-like domain - - - 0.00000000000007929 75.0
TLS2_k127_6211867_5 repeat-containing protein - - - 0.000000000007516 77.0
TLS2_k127_621195_0 PHP domain protein - - - 3.845e-280 878.0
TLS2_k127_621195_1 Metalloenzyme superfamily K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 424.0
TLS2_k127_621195_2 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 354.0
TLS2_k127_621195_3 gluconolactonase K01053,K14274 GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 308.0
TLS2_k127_621195_4 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 305.0
TLS2_k127_621195_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000005508 207.0
TLS2_k127_621195_7 Class V aminotransferase K04127 - 5.1.1.17 0.00000000000002852 78.0
TLS2_k127_621812_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 3081.0
TLS2_k127_621812_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.505e-218 683.0
TLS2_k127_621812_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 604.0
TLS2_k127_621812_3 Domain of unknown function (DUF1998) K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 509.0
TLS2_k127_621812_4 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 471.0
TLS2_k127_621812_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 368.0
TLS2_k127_621812_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 310.0
TLS2_k127_6221446_0 - - - - 0.00000000000000000000000000000000000000000000000000000000127 209.0
TLS2_k127_6223019_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 2.496e-266 837.0
TLS2_k127_6223019_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 1.812e-234 731.0
TLS2_k127_6223019_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 400.0
TLS2_k127_6223019_3 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000009848 197.0
TLS2_k127_6223019_4 - - - - 0.000000003131 64.0
TLS2_k127_622767_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 589.0
TLS2_k127_622767_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000005305 154.0
TLS2_k127_6243903_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
TLS2_k127_6243903_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000001753 171.0
TLS2_k127_6243903_3 Carboxypeptidase regulatory-like domain - - - 0.000003869 56.0
TLS2_k127_6248294_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 346.0
TLS2_k127_6248294_1 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001973 253.0
TLS2_k127_6250080_0 TIGRFAM ATPase, FliI YscN family K02412 - 3.6.3.14 3.01e-197 631.0
TLS2_k127_6250080_1 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 464.0
TLS2_k127_6250080_10 Flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000000000134 147.0
TLS2_k127_6250080_11 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000002762 139.0
TLS2_k127_6250080_12 Chemotaxis phosphatase CheX - - - 0.0000000001874 69.0
TLS2_k127_6250080_13 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000001039 63.0
TLS2_k127_6250080_2 ATP-binding region ATPase domain protein K02487,K03407,K06596 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 467.0
TLS2_k127_6250080_3 flagellar motor switch protein FliG K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 381.0
TLS2_k127_6250080_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 334.0
TLS2_k127_6250080_5 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000339 270.0
TLS2_k127_6250080_6 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000003149 189.0
TLS2_k127_6250080_7 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000001852 179.0
TLS2_k127_6250080_8 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000172 166.0
TLS2_k127_6250080_9 Chemotaxis phosphatase CheX K03409 - - 0.00000000000000000000000000000000000001435 154.0
TLS2_k127_625515_0 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 411.0
TLS2_k127_625515_1 Histidine kinase - - - 0.000000000000000000000000000000000000003156 160.0
TLS2_k127_625515_2 Membrane - - - 0.0000000000000000000003895 109.0
TLS2_k127_625515_3 GntR family transcriptional regulator - - - 0.0000000000000000005903 91.0
TLS2_k127_625773_0 Carboxypeptidase regulatory-like domain - - - 2.006e-256 831.0
TLS2_k127_625773_1 helix_turn_helix, Lux Regulon K03088 - - 0.0000000000000000000000000000156 124.0
TLS2_k127_6261993_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000879 233.0
TLS2_k127_6261993_1 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001278 228.0
TLS2_k127_6261993_2 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000002042 158.0
TLS2_k127_6265796_0 WD40 repeats K20332 - - 0.0000000000000000000000000000000000000000055 164.0
TLS2_k127_6265796_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000001466 151.0
TLS2_k127_6276989_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.509e-218 701.0
TLS2_k127_6276989_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 608.0
TLS2_k127_6276989_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 384.0
TLS2_k127_6276989_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002057 252.0
TLS2_k127_6276989_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003106 211.0
TLS2_k127_6276989_5 - - - - 0.000000000000003721 81.0
TLS2_k127_6279980_0 Carboxypeptidase regulatory-like domain - - - 0.0 1102.0
TLS2_k127_6279980_1 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 302.0
TLS2_k127_6279980_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001117 233.0
TLS2_k127_6288636_0 transport - - - 2.139e-217 711.0
TLS2_k127_6288636_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 475.0
TLS2_k127_6288636_2 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000000000000000000000000000000008577 224.0
TLS2_k127_6288636_3 mitochondrion morphogenesis K06195 - - 0.0000000000000000000000000000000000000000000000000000000000371 207.0
TLS2_k127_6295985_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 418.0
TLS2_k127_6295985_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 417.0
TLS2_k127_6295985_2 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 380.0
TLS2_k127_6295985_3 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447 282.0
TLS2_k127_6295985_4 - - - - 0.00000000000000000000000000000000000000000000000000007142 195.0
TLS2_k127_6296007_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 480.0
TLS2_k127_6296007_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002752 249.0
TLS2_k127_6296007_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001466 246.0
TLS2_k127_6296007_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000001199 141.0
TLS2_k127_6313252_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 565.0
TLS2_k127_6313252_1 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000002804 218.0
TLS2_k127_6313252_2 - - - - 0.000000000000000000000000000000000000000000000000000000006766 211.0
TLS2_k127_6313252_3 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000005815 151.0
TLS2_k127_6313252_4 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000001799 94.0
TLS2_k127_6313252_5 MacB-like periplasmic core domain - - - 0.000000000002524 70.0
TLS2_k127_631415_0 binding domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 385.0
TLS2_k127_631415_1 Mandelate racemase muconate lactonizing enzyme K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000001257 244.0
TLS2_k127_631415_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000001067 238.0
TLS2_k127_631415_3 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000003766 241.0
TLS2_k127_631415_4 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000002006 143.0
TLS2_k127_6315355_0 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 473.0
TLS2_k127_6315355_1 Planctomycete cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 403.0
TLS2_k127_6315355_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000005243 172.0
TLS2_k127_631859_0 Protein of unknown function (DUF1698) K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 376.0
TLS2_k127_631859_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 344.0
TLS2_k127_631859_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 305.0
TLS2_k127_631859_3 Glycosyl hydrolase catalytic core - - - 0.000000000000000000000000000000000000006536 146.0
TLS2_k127_6319561_0 mitochondrial gene expression - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 344.0
TLS2_k127_632590_0 symporter activity - - - 1.835e-213 673.0
TLS2_k127_632590_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 572.0
TLS2_k127_632590_2 AMP-binding enzyme K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 564.0
TLS2_k127_632590_3 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 454.0
TLS2_k127_632590_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005047 280.0
TLS2_k127_6326378_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 487.0
TLS2_k127_6326378_1 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000002799 194.0
TLS2_k127_6326378_2 Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000004422 143.0
TLS2_k127_6326378_3 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000003383 114.0
TLS2_k127_6326378_4 protein-disulfide reductase activity K04084 - 1.8.1.8 0.000000001455 62.0
TLS2_k127_633924_0 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.0 1124.0
TLS2_k127_633924_1 Sigma-54 interaction domain - - - 6.082e-205 649.0
TLS2_k127_633924_2 Sugar-binding cellulase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 432.0
TLS2_k127_633924_3 gluconolactonase activity K01053,K13735 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 351.0
TLS2_k127_633924_4 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001249 287.0
TLS2_k127_633924_5 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000002819 227.0
TLS2_k127_633924_6 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000685 114.0
TLS2_k127_634116_0 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000001532 199.0
TLS2_k127_634116_1 - - - - 0.0000000000000000000000000000000000000000000000002366 188.0
TLS2_k127_634116_2 Leukotriene A4 hydrolase, C-terminal - - - 0.000000000008185 66.0
TLS2_k127_6346932_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 444.0
TLS2_k127_6346932_1 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 437.0
TLS2_k127_6346932_10 - - - - 0.0000000000000000000000000000000000000002371 157.0
TLS2_k127_6346932_11 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000001231 119.0
TLS2_k127_6346932_12 - - - - 0.0000000000000000001782 89.0
TLS2_k127_6346932_2 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 306.0
TLS2_k127_6346932_3 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 301.0
TLS2_k127_6346932_4 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 290.0
TLS2_k127_6346932_6 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000000000000000000000000000000000000000000000000007452 224.0
TLS2_k127_6346932_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000001808 216.0
TLS2_k127_6346932_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.00000000000000000000000000000000000000000000000000000005946 201.0
TLS2_k127_6346932_9 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000000000000000000000005006 181.0
TLS2_k127_6348578_0 carboxylic acid catabolic process K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 331.0
TLS2_k127_6348578_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000002876 188.0
TLS2_k127_6352863_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 600.0
TLS2_k127_6352863_1 Divalent cation transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002345 279.0
TLS2_k127_6352863_2 - - - - 0.000000000000001028 83.0
TLS2_k127_6352863_3 OsmC-like protein - - - 0.0005817 44.0
TLS2_k127_6353351_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000001063 224.0
TLS2_k127_6353351_1 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000224 151.0
TLS2_k127_6353351_2 Putative MetA-pathway of phenol degradation - - - 0.0000001274 62.0
TLS2_k127_6353351_3 chemotaxis K03406 - - 0.0002609 48.0
TLS2_k127_6361867_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000001227 199.0
TLS2_k127_6361867_1 PFAM response regulator receiver - - - 0.000000000000000000002518 101.0
TLS2_k127_6361867_2 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000006122 100.0
TLS2_k127_6371418_0 Transposase DDE domain - - - 4.89e-200 640.0
TLS2_k127_6371418_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 294.0
TLS2_k127_6371418_2 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000000000004608 147.0
TLS2_k127_6371418_3 Belongs to the helicase family. UvrD subfamily - - - 0.000000000000000001135 88.0
TLS2_k127_63747_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 366.0
TLS2_k127_63747_1 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003708 252.0
TLS2_k127_63747_2 Histidine kinase - - - 0.0000000000000015 85.0
TLS2_k127_6377783_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 8.133e-275 864.0
TLS2_k127_6377783_1 Alpha-L-fucosidase K01206 - 3.2.1.51 1.582e-242 759.0
TLS2_k127_6377783_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 593.0
TLS2_k127_6377783_3 COG3119 Arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004104 261.0
TLS2_k127_6377783_4 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000008296 229.0
TLS2_k127_6377783_5 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000466 120.0
TLS2_k127_6382630_0 Histidine kinase - - - 0.0000000000000000000000000000000000004049 143.0
TLS2_k127_6382630_1 - - - - 0.000000000157 67.0
TLS2_k127_6382630_2 Integrase core domain - - - 0.000000001842 60.0
TLS2_k127_6382630_3 transposition K07497 - - 0.00002133 50.0
TLS2_k127_639955_0 UPF0365 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
TLS2_k127_639955_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 430.0
TLS2_k127_639955_2 COG3119 Arylsulfatase A K01138 - - 0.000000000000000000000000000000000000000000000004623 190.0
TLS2_k127_639955_3 AI-2E family transporter - - - 0.00000000000000000000000000000001443 141.0
TLS2_k127_6400453_0 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 3.799e-217 691.0
TLS2_k127_6400453_1 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000108 274.0
TLS2_k127_6400453_2 Acts as a magnesium transporter K06213 - - 0.00000000002195 70.0
TLS2_k127_6405968_0 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 504.0
TLS2_k127_6405968_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 379.0
TLS2_k127_6405968_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006458 259.0
TLS2_k127_6405968_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000002913 203.0
TLS2_k127_6405968_4 Membrane - - - 0.00000000000000000000000000001363 119.0
TLS2_k127_6405968_5 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.00000000000000000035 90.0
TLS2_k127_6407949_0 RepB DNA-primase from phage plasmid - - - 0.00000000000000000000000000000000000000000000006709 181.0
TLS2_k127_6407949_1 Plasmid stabilization system - - - 0.000000000000000000000005637 104.0
TLS2_k127_6426303_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 606.0
TLS2_k127_6426303_1 Heparinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 604.0
TLS2_k127_6426303_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000002747 128.0
TLS2_k127_6426303_3 - - - - 0.0000000000000000000000000211 112.0
TLS2_k127_6426461_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 336.0
TLS2_k127_6426461_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000002204 254.0
TLS2_k127_6430084_0 Rhodanese-like domain K01069 - 3.1.2.6 4.806e-223 698.0
TLS2_k127_6430084_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 398.0
TLS2_k127_6430084_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 288.0
TLS2_k127_6430084_3 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000001775 183.0
TLS2_k127_6431354_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 621.0
TLS2_k127_6431354_1 COGs COG0673 dehydrogenase and related protein - - - 0.000000000000000000000001083 112.0
TLS2_k127_6431354_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000001453 83.0
TLS2_k127_6431354_3 and related - - - 0.0000000255 57.0
TLS2_k127_6433496_0 Lactonase, 7-bladed beta-propeller - - - 9.898e-320 999.0
TLS2_k127_6433496_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 6.815e-230 723.0
TLS2_k127_6433496_2 phage Terminase large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 571.0
TLS2_k127_6433496_3 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000009949 197.0
TLS2_k127_6433496_4 - - - - 0.0000000000000000000000000000000000000000000000002087 178.0
TLS2_k127_6433496_5 peptidyl-prolyl cis-trans isomerase activity K03769,K03770,K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000001013 176.0
TLS2_k127_6433496_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000002176 131.0
TLS2_k127_6433496_7 - - - - 0.000000000000000007499 94.0
TLS2_k127_6433496_8 Rhodanese Homology Domain - - - 0.000000000889 63.0
TLS2_k127_6433626_0 - - - - 2.185e-239 770.0
TLS2_k127_6433626_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 445.0
TLS2_k127_6433626_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 308.0
TLS2_k127_6433626_3 PFAM Chemotaxis methyl-accepting receptor, signalling K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004002 281.0
TLS2_k127_6433626_4 Glycosyl Hydrolase Family 88 - - - 0.00000000000000000000000000000000001885 157.0
TLS2_k127_6439841_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 603.0
TLS2_k127_6439841_1 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 569.0
TLS2_k127_6439841_2 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 568.0
TLS2_k127_6439841_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000002712 214.0
TLS2_k127_6439841_4 antisigma factor binding - - - 0.000000000000000000000000000000000000000000000000000003467 199.0
TLS2_k127_6439841_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000002138 200.0
TLS2_k127_6439841_7 Thioesterase superfamily - - - 0.0000000000000000000000000000000003646 135.0
TLS2_k127_6439841_8 - - - - 0.0000000000000000000000001356 115.0
TLS2_k127_6439841_9 - - - - 0.00000000468 64.0
TLS2_k127_6451607_0 reverse transcriptase - - - 1.76e-212 667.0
TLS2_k127_6451607_1 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 400.0
TLS2_k127_6451607_2 High confidence in function and specificity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 352.0
TLS2_k127_6451607_4 transposase activity - - - 0.0000000000299 68.0
TLS2_k127_6451607_5 KTSC domain - - - 0.00000000008668 66.0
TLS2_k127_6451607_6 esterase K12686 - - 0.0000001456 57.0
TLS2_k127_6451607_7 - - - - 0.00001004 51.0
TLS2_k127_6453315_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.813e-255 809.0
TLS2_k127_6453315_1 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006228 273.0
TLS2_k127_6453315_2 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000001423 249.0
TLS2_k127_6453315_3 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00000000000000000000000000000000001454 146.0
TLS2_k127_6463751_0 ATP-dependent DNA helicase activity K01144,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 326.0
TLS2_k127_6463751_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00042 - 1.1.1.60 0.00000000000000000000000000000000000001806 147.0
TLS2_k127_6478089_0 mandelate racemase muconate lactonizing K08323 - 4.2.1.8 1.399e-222 704.0
TLS2_k127_6478089_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 464.0
TLS2_k127_6478089_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 332.0
TLS2_k127_6478089_3 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000004341 178.0
TLS2_k127_6478089_4 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000006297 138.0
TLS2_k127_6494121_0 - - - - 1.421e-294 917.0
TLS2_k127_6494121_1 protocatechuate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 375.0
TLS2_k127_6494121_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000001171 51.0
TLS2_k127_6498856_0 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 554.0
TLS2_k127_6498856_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007074 264.0
TLS2_k127_6498856_2 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001526 248.0
TLS2_k127_6498856_3 Domain of unknown function (DUF4397) - - - 0.0000000000000000000005102 105.0
TLS2_k127_6498856_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000005969 91.0
TLS2_k127_6498856_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.00000000000000007252 85.0
TLS2_k127_6507438_0 Belongs to the ClpA ClpB family K03696 - - 1.888e-234 730.0
TLS2_k127_6507438_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 589.0
TLS2_k127_6507438_10 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000007024 144.0
TLS2_k127_6507438_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000007155 134.0
TLS2_k127_6507438_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000004181 87.0
TLS2_k127_6507438_14 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000005262 59.0
TLS2_k127_6507438_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 589.0
TLS2_k127_6507438_3 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 458.0
TLS2_k127_6507438_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 448.0
TLS2_k127_6507438_5 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 331.0
TLS2_k127_6507438_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 289.0
TLS2_k127_6507438_7 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001083 261.0
TLS2_k127_6507438_8 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000001529 224.0
TLS2_k127_6507438_9 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000006615 192.0
TLS2_k127_6521808_0 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 6.314e-279 884.0
TLS2_k127_6521808_1 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 3.292e-220 700.0
TLS2_k127_6521808_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 401.0
TLS2_k127_652544_0 PQQ-like domain K00114 - 1.1.2.8 3.891e-212 673.0
TLS2_k127_652544_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002633 249.0
TLS2_k127_652544_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000003911 167.0
TLS2_k127_6541592_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 480.0
TLS2_k127_6541592_1 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 461.0
TLS2_k127_6541592_2 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 446.0
TLS2_k127_6547096_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 586.0
TLS2_k127_6547096_1 sulfuric ester hydrolase activity K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 394.0
TLS2_k127_6547096_2 Protein of unknown function (DUF1264) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 324.0
TLS2_k127_6547096_3 transcription factor binding K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000002092 220.0
TLS2_k127_6547096_4 GDSL-like Lipase/Acylhydrolase K12686 - - 0.00000000000000000000000000000000001192 149.0
TLS2_k127_6547096_5 response regulator, receiver K02485 - - 0.0000000000000000000000001577 111.0
TLS2_k127_6553493_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 389.0
TLS2_k127_6553493_1 COG3119 Arylsulfatase A and related enzymes K01138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003909 262.0
TLS2_k127_6553493_2 Sulfatase - - - 0.0000001288 54.0
TLS2_k127_6554857_0 reverse transcriptase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 367.0
TLS2_k127_6554857_1 - - - - 0.0000000000000000000000000000000000000000000006889 171.0
TLS2_k127_6554857_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000006148 112.0
TLS2_k127_6554857_3 Belongs to the 'phage' integrase family K03733,K04763 - - 0.000000000000001653 84.0
TLS2_k127_656296_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 455.0
TLS2_k127_656296_1 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000139 212.0
TLS2_k127_656296_2 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000000000000000001414 192.0
TLS2_k127_656296_4 phosphorelay signal transduction system K03974 - - 0.00000000000000001443 87.0
TLS2_k127_6574902_0 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 526.0
TLS2_k127_6577475_0 efflux transmembrane transporter activity - - - 5.579e-238 768.0
TLS2_k127_6577475_1 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 423.0
TLS2_k127_6577475_2 Calcineurin-like phosphoesterase superfamily domain K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 289.0
TLS2_k127_6577475_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000004097 201.0
TLS2_k127_6577475_4 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000008858 163.0
TLS2_k127_6577475_5 Belongs to the HpcH HpaI aldolase family K01630,K02510,K12660 - 4.1.2.20,4.1.2.52,4.1.2.53 0.000000000000000000000000000000001766 133.0
TLS2_k127_6577475_6 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000002898 106.0
TLS2_k127_6577475_7 TonB-dependent receptor - - - 0.00000000000000000000003286 106.0
TLS2_k127_6577508_0 Protein of unknown function (DUF1501) - - - 5.42e-250 777.0
TLS2_k127_6577508_1 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 454.0
TLS2_k127_6577508_2 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 442.0
TLS2_k127_6577508_3 Cytochrome c, class I - - - 0.00000000000000000003046 97.0
TLS2_k127_6581630_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 310.0
TLS2_k127_6581630_1 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002692 233.0
TLS2_k127_6581630_2 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000009951 170.0
TLS2_k127_6592131_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 471.0
TLS2_k127_6592131_1 WD40-like Beta Propeller Repeat K01730 - 4.2.2.6 0.00000000000000000000000000000000000000000000000000000003024 212.0
TLS2_k127_6592131_2 peptidase M10A and M12B matrixin and adamalysin K01406 - 3.4.24.40 0.00000000000001023 84.0
TLS2_k127_6595850_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 314.0
TLS2_k127_6595850_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 307.0
TLS2_k127_6595850_2 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000002494 177.0
TLS2_k127_6595850_3 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000004727 173.0
TLS2_k127_6595850_4 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.0000000000000000000000000001334 127.0
TLS2_k127_6595850_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000005187 121.0
TLS2_k127_6596320_0 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 0.0 1049.0
TLS2_k127_6596320_1 Protein tyrosine kinase - - - 0.00000000000000000001508 100.0
TLS2_k127_6596320_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000004418 68.0
TLS2_k127_6596353_0 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 394.0
TLS2_k127_6596353_1 PFAM glucosamine galactosamine-6-phosphate isomerase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 303.0
TLS2_k127_6596353_2 RNA recognition motif - - - 0.0000000000000000000000000000001549 127.0
TLS2_k127_6596353_3 macromolecule localization K09690 - - 0.00003046 49.0
TLS2_k127_6596989_0 siderophore transport K02014 - - 2.151e-309 983.0
TLS2_k127_6596989_1 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 302.0
TLS2_k127_6596989_2 Belongs to the glycosyl hydrolase 28 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 312.0
TLS2_k127_6596989_3 PBS lyase HEAT-like repeat - - - 0.000000000000000000000003958 107.0
TLS2_k127_6596989_4 Transcriptional K02529,K03484 - - 0.0000000000001041 78.0
TLS2_k127_6602244_0 HELICc2 K03722 - 3.6.4.12 8.836e-292 907.0
TLS2_k127_6602244_1 PFAM Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 575.0
TLS2_k127_6602244_2 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 510.0
TLS2_k127_6602244_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 318.0
TLS2_k127_6602244_4 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000513 201.0
TLS2_k127_6602244_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000001365 198.0
TLS2_k127_6602244_6 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000006319 184.0
TLS2_k127_6602244_7 - - - - 0.000000000000000000001219 100.0
TLS2_k127_6612715_0 mannonate dehydratase activity K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 481.0
TLS2_k127_6612715_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 466.0
TLS2_k127_6612715_2 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.0000000000000000000000000000000000000000000000000000000000005178 228.0
TLS2_k127_6620705_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 328.0
TLS2_k127_6620705_1 PFAM WD40-like beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 332.0
TLS2_k127_6620705_2 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003162 263.0
TLS2_k127_6620705_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000003717 219.0
TLS2_k127_6627588_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 588.0
TLS2_k127_6627588_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 407.0
TLS2_k127_6627588_2 TonB-dependent receptor K02014,K16089 - - 0.00000000000000000000000000000000000000000000000000001181 197.0
TLS2_k127_6627588_3 two-component system K02485 - - 0.0000000000000000000000000000000000000000000000000003788 189.0
TLS2_k127_6627588_4 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000000000000004632 147.0
TLS2_k127_6637361_0 tail specific protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 297.0
TLS2_k127_6637361_1 PFAM 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000000000002397 243.0
TLS2_k127_6637361_2 Catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate K01631 - 4.1.2.21 0.00000000000000000000000000000000000000000000000000000001367 205.0
TLS2_k127_6637361_4 TRANSCRIPTIONal - - - 0.0000000000000000009793 89.0
TLS2_k127_6642178_0 Outer membrane protein beta-barrel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002521 281.0
TLS2_k127_6642178_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000001364 149.0
TLS2_k127_6642178_2 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000001875 77.0
TLS2_k127_6643161_0 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 638.0
TLS2_k127_6643161_1 COG0277 FAD FMN-containing dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 469.0
TLS2_k127_6655453_0 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 430.0
TLS2_k127_6659562_0 alginic acid biosynthetic process K01729 - 4.2.2.3 2.312e-303 942.0
TLS2_k127_6659562_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 517.0
TLS2_k127_6659562_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 458.0
TLS2_k127_6659562_3 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000004454 205.0
TLS2_k127_6667752_0 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 535.0
TLS2_k127_6667752_1 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000136 227.0
TLS2_k127_6672626_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1087.0
TLS2_k127_6672626_1 mandelate racemase muconate lactonizing K22209 - 4.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 542.0
TLS2_k127_6672626_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 514.0
TLS2_k127_6672626_3 Pectic acid lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 387.0
TLS2_k127_6672626_4 RsbT co-antagonist protein rsbRD N-terminal domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 327.0
TLS2_k127_6672626_5 Stage II sporulation protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000004263 233.0
TLS2_k127_6672626_6 transporter antisigma-factor antagonist STAS K17762 - - 0.000000000000000000000000000000000000000000000000004207 186.0
TLS2_k127_6672626_7 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000000005536 179.0
TLS2_k127_6672626_8 Histidine phosphatase superfamily (branch 1) K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000001242 172.0
TLS2_k127_6673780_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 475.0
TLS2_k127_6673780_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 407.0
TLS2_k127_6673780_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 392.0
TLS2_k127_6673780_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 368.0
TLS2_k127_6673780_4 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 333.0
TLS2_k127_6673780_5 Glycosyl transferase, family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 320.0
TLS2_k127_6673780_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001853 287.0
TLS2_k127_6673780_7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
TLS2_k127_6673780_8 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000009189 156.0
TLS2_k127_6681507_0 Histidine kinase K03412,K03413,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 0.0 1304.0
TLS2_k127_6681507_1 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 264.0
TLS2_k127_6681507_2 - - - - 0.000000000000000000000000000000000000000000000003879 183.0
TLS2_k127_6681507_3 PepSY-associated TM region - - - 0.0000000002637 63.0
TLS2_k127_6691043_0 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 475.0
TLS2_k127_6691043_1 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 381.0
TLS2_k127_6691043_2 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000104 190.0
TLS2_k127_6691043_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000007794 106.0
TLS2_k127_6691043_4 Transcriptional regulatory protein, C terminal - - - 0.0000000000000003321 91.0
TLS2_k127_6691043_5 cellulose binding - - - 0.000000000001109 73.0
TLS2_k127_6691043_6 amine dehydrogenase activity K12287 - - 0.00000009054 64.0
TLS2_k127_6693489_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 454.0
TLS2_k127_6693489_1 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000002574 220.0
TLS2_k127_6693489_2 PFAM Fimbrial assembly family protein - - - 0.00000000001551 68.0
TLS2_k127_671899_0 Protein of unknown function (DUF4038) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 593.0
TLS2_k127_671899_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 476.0
TLS2_k127_671899_2 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 398.0
TLS2_k127_671899_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001241 276.0
TLS2_k127_671899_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000002268 224.0
TLS2_k127_671899_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000004443 58.0
TLS2_k127_6719128_0 Outer membrane receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 436.0
TLS2_k127_6719128_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000001829 227.0
TLS2_k127_6719128_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000002737 201.0
TLS2_k127_6719128_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000002336 160.0
TLS2_k127_6719128_4 Major facilitator Superfamily - - - 0.00001271 48.0
TLS2_k127_6721182_0 PFAM peptidase U62 modulator of DNA gyrase - - - 2.731e-210 668.0
TLS2_k127_6721182_1 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 526.0
TLS2_k127_6721182_2 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000007114 188.0
TLS2_k127_6721182_3 response regulator K02479,K07684,K07685 - - 0.00000000000000000000000000000000000000000000000019 184.0
TLS2_k127_6721182_4 Phosphotransferase enzyme family K00899 - 2.7.1.100 0.00000008021 59.0
TLS2_k127_6726451_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.32e-222 706.0
TLS2_k127_6726451_1 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 441.0
TLS2_k127_6726451_2 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
TLS2_k127_6726451_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
TLS2_k127_6726451_4 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
TLS2_k127_6726722_0 Protein of unknown function (DUF507) K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003773 255.0
TLS2_k127_6726722_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852 GO:0003674,GO:0003824,GO:0004747,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019303,GO:0019321,GO:0019323,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.15,2.7.1.4 0.000000000000000000000000000006072 121.0
TLS2_k127_6726722_2 - - - - 0.000000000000000000001676 102.0
TLS2_k127_6739584_0 MacB-like periplasmic core domain - - - 0.0 1096.0
TLS2_k127_6739584_1 Belongs to the glycosyl hydrolase 57 family - - - 1.314e-317 991.0
TLS2_k127_6739584_2 TonB-dependent receptor - - - 3.715e-215 707.0
TLS2_k127_6739584_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 464.0
TLS2_k127_6739584_4 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 382.0
TLS2_k127_6739584_5 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000005362 238.0
TLS2_k127_6739584_6 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000000000001371 211.0
TLS2_k127_6739584_7 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000002948 129.0
TLS2_k127_6739584_8 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.00000000000000000000004072 110.0
TLS2_k127_6762739_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 434.0
TLS2_k127_6762739_1 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002912 284.0
TLS2_k127_6762739_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000006033 192.0
TLS2_k127_6773386_0 exo-alpha-(2->6)-sialidase activity K01179 - 3.2.1.4 1.305e-289 900.0
TLS2_k127_6773386_1 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 1.172e-229 722.0
TLS2_k127_6773386_2 Carboxypeptidase regulatory-like domain - - - 4.966e-221 723.0
TLS2_k127_6773386_3 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 320.0
TLS2_k127_6773386_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000008854 185.0
TLS2_k127_6789889_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 596.0
TLS2_k127_6789889_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 411.0
TLS2_k127_6790195_0 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000002002 234.0
TLS2_k127_6790195_1 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000004152 211.0
TLS2_k127_6790195_2 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000001385 203.0
TLS2_k127_6790195_3 ABC transporter - - - 0.0000000000000000000000000000000000000001937 151.0
TLS2_k127_6794857_0 PFAM ABC transporter related K01990,K16907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 353.0
TLS2_k127_6794857_1 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000008444 160.0
TLS2_k127_6794857_2 ATPase, P-type transporting, HAD superfamily, subfamily IC K16905 - - 0.0000000000000000000000000000000000000001582 160.0
TLS2_k127_6794857_3 transmembrane transport K16906 - - 0.0000000000000000000000000000000000006074 149.0
TLS2_k127_6794857_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000006662 128.0
TLS2_k127_6794857_5 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000001265 134.0
TLS2_k127_6804929_0 heat shock protein 70 K04043,K04044 - - 5.018e-279 869.0
TLS2_k127_6804929_1 cystathionine K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 577.0
TLS2_k127_6804929_10 iron-sulfur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000001919 115.0
TLS2_k127_6804929_2 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 488.0
TLS2_k127_6804929_3 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 357.0
TLS2_k127_6804929_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003562 240.0
TLS2_k127_6804929_5 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000005906 221.0
TLS2_k127_6804929_6 PFAM heat shock protein DnaJ K04082 - - 0.0000000000000000000000000000000000000000000000007467 182.0
TLS2_k127_6804929_7 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000006706 168.0
TLS2_k127_6804929_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000001532 149.0
TLS2_k127_6804929_9 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000009852 139.0
TLS2_k127_6810165_0 COG COG3119 Arylsulfatase A and related enzymes K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 421.0
TLS2_k127_6810165_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 317.0
TLS2_k127_6810165_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 297.0
TLS2_k127_6816509_0 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 318.0
TLS2_k127_6816509_1 pilus organization - - - 0.000000000000000000000000000001326 139.0
TLS2_k127_6820740_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 451.0
TLS2_k127_6820740_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003131 257.0
TLS2_k127_6820740_2 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000008209 224.0
TLS2_k127_682469_0 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 471.0
TLS2_k127_682469_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002135 297.0
TLS2_k127_6830211_0 Sodium:solute symporter family - - - 1.178e-288 898.0
TLS2_k127_6830211_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 5.471e-232 724.0
TLS2_k127_6830211_2 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 578.0
TLS2_k127_6830211_3 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 510.0
TLS2_k127_6830211_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 437.0
TLS2_k127_6830211_5 GHMP kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 409.0
TLS2_k127_6830211_6 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 320.0
TLS2_k127_6830211_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000006017 209.0
TLS2_k127_6830211_8 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000001063 74.0
TLS2_k127_6838472_0 PFAM Gamma-glutamyltranspeptidase - - - 2.117e-202 644.0
TLS2_k127_6838472_1 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000003791 211.0
TLS2_k127_6841947_0 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 389.0
TLS2_k127_6841947_1 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000393 286.0
TLS2_k127_6851924_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.321e-290 899.0
TLS2_k127_6851924_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 481.0
TLS2_k127_6851924_2 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 387.0
TLS2_k127_6851924_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 367.0
TLS2_k127_6851924_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 344.0
TLS2_k127_6851924_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 300.0
TLS2_k127_6851924_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002255 231.0
TLS2_k127_6851924_7 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000003635 216.0
TLS2_k127_6851924_8 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000003185 190.0
TLS2_k127_6851924_9 PFAM TPR repeat-containing protein - - - 0.000000000006413 76.0
TLS2_k127_6859760_0 deoxyhypusine monooxygenase activity - - - 0.0000001227 62.0
TLS2_k127_6859760_1 Beta-L-arabinofuranosidase, GH127 - - - 0.0000004844 61.0
TLS2_k127_6866234_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001487 273.0
TLS2_k127_6866234_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003071 258.0
TLS2_k127_6866234_2 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000311 252.0
TLS2_k127_6866234_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000004272 168.0
TLS2_k127_6866943_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.951e-225 721.0
TLS2_k127_6866943_1 Thioredoxin-like K04084 - 1.8.1.8 9.437e-223 705.0
TLS2_k127_6870276_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 540.0
TLS2_k127_6870276_1 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 442.0
TLS2_k127_6870276_2 Predicted metal-binding protein (DUF2103) - - - 0.00000000000000000000000000000000001785 137.0
TLS2_k127_6873876_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 509.0
TLS2_k127_6873876_1 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 342.0
TLS2_k127_6873876_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006324 246.0
TLS2_k127_6873876_4 B12 binding domain - - - 0.000000000000006383 88.0
TLS2_k127_6873962_0 Domain of unknown function (DUF1998) K06877 - - 5.101e-197 622.0
TLS2_k127_6873962_1 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 519.0
TLS2_k127_6879979_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 445.0
TLS2_k127_6879979_1 PFAM O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 301.0
TLS2_k127_6879979_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009796 281.0
TLS2_k127_6879979_3 PFAM O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007382 243.0
TLS2_k127_6879979_4 nuclease activity K07062 - - 0.00001866 48.0
TLS2_k127_6881411_0 TniQ - - - 0.000000000000000000000000579 119.0
TLS2_k127_6881411_1 Bacterial TniB protein - - - 0.000000000000000000000001344 111.0
TLS2_k127_6889243_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 565.0
TLS2_k127_6889243_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 514.0
TLS2_k127_6889243_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 425.0
TLS2_k127_6889243_3 PFAM aminotransferase class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 399.0
TLS2_k127_6889243_4 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 384.0
TLS2_k127_6889243_5 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 364.0
TLS2_k127_6889243_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 342.0
TLS2_k127_6889243_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000002842 168.0
TLS2_k127_6889243_8 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000000000000000000000002151 136.0
TLS2_k127_6889624_0 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 597.0
TLS2_k127_6889624_1 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000005974 218.0
TLS2_k127_6889624_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000003584 208.0
TLS2_k127_6889624_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000001102 102.0
TLS2_k127_6891721_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 396.0
TLS2_k127_6891721_1 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 342.0
TLS2_k127_6891721_2 Domain of Unknown Function (DUF1080) - - - 0.00000000000000001795 92.0
TLS2_k127_6895251_0 PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 462.0
TLS2_k127_69_0 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 398.0
TLS2_k127_69_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 344.0
TLS2_k127_69_2 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000007689 203.0
TLS2_k127_69_3 - - - - 0.00000000000004866 77.0
TLS2_k127_6906376_0 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000009997 162.0
TLS2_k127_6906376_1 Domain of unknown function (DUF2382) - - - 0.00000000000000004798 87.0
TLS2_k127_6906376_2 NmrA-like family - - - 0.0000000000000001959 81.0
TLS2_k127_6906376_3 Transcriptional regulator - - - 0.0000000000000004617 83.0
TLS2_k127_6907309_0 Putative glutamine amidotransferase - - - 4.316e-260 821.0
TLS2_k127_6907309_1 Tetratricopeptide repeats - - - 1.135e-216 690.0
TLS2_k127_6907309_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 370.0
TLS2_k127_6907309_3 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 362.0
TLS2_k127_6907309_4 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 304.0
TLS2_k127_6907309_5 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000007305 203.0
TLS2_k127_6907309_6 COG1651 Protein-disulfide isomerase - - - 0.00000000005698 71.0
TLS2_k127_6909909_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 481.0
TLS2_k127_6909909_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000001631 222.0
TLS2_k127_6909909_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000001122 73.0
TLS2_k127_6909909_3 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000002376 66.0
TLS2_k127_6910448_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.749e-303 940.0
TLS2_k127_6910448_1 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 503.0
TLS2_k127_6910448_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 480.0
TLS2_k127_6910448_3 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 475.0
TLS2_k127_6910448_4 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 461.0
TLS2_k127_6910448_5 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 451.0
TLS2_k127_6910448_6 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 416.0
TLS2_k127_6910448_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 329.0
TLS2_k127_6910448_8 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000001384 177.0
TLS2_k127_6913087_0 Zinc carboxypeptidase - - - 4.212e-207 676.0
TLS2_k127_6913087_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 492.0
TLS2_k127_6913087_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 473.0
TLS2_k127_6918824_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 397.0
TLS2_k127_6918824_1 Protein of unknown function (DUF1501) - - - 0.0003959 49.0
TLS2_k127_6919923_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 561.0
TLS2_k127_6919923_1 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 426.0
TLS2_k127_6919923_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000009579 168.0
TLS2_k127_6924925_0 amino acid carrier protein K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 476.0
TLS2_k127_6924925_1 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007517 265.0
TLS2_k127_6926658_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K00575,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 533.0
TLS2_k127_6926658_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006172 259.0
TLS2_k127_6926658_2 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000009737 100.0
TLS2_k127_6935600_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 305.0
TLS2_k127_6935600_1 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000008183 139.0
TLS2_k127_6943821_0 PFAM natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 456.0
TLS2_k127_6943821_1 protein import - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 333.0
TLS2_k127_6945342_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000005793 117.0
TLS2_k127_6945342_1 iron dependent repressor K01356,K03709 - 3.4.21.88 0.0000000000000000000000111 103.0
TLS2_k127_6945342_2 - K18829 - - 0.00000000000000000000006039 104.0
TLS2_k127_6945342_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000008403 108.0
TLS2_k127_6945342_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000005577 83.0
TLS2_k127_6949523_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 505.0
TLS2_k127_6949523_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 405.0
TLS2_k127_6949523_10 Iodothyronine deiodinase - - - 0.000000000000000000000000000001957 124.0
TLS2_k127_6949523_11 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000007078 133.0
TLS2_k127_6949523_12 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000001114 96.0
TLS2_k127_6949523_13 - - - - 0.00000000000000000002849 97.0
TLS2_k127_6949523_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 396.0
TLS2_k127_6949523_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 348.0
TLS2_k127_6949523_4 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005648 281.0
TLS2_k127_6949523_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008997 271.0
TLS2_k127_6949523_6 PFAM Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 277.0
TLS2_k127_6949523_7 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000002594 179.0
TLS2_k127_6949523_8 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000000000341 162.0
TLS2_k127_6949523_9 Tryptophan halogenase - - - 0.0000000000000000000000000000000000009164 142.0
TLS2_k127_6956440_0 glutamine synthetase K01915 - 6.3.1.2 7.597e-279 860.0
TLS2_k127_6956440_1 phosphoribosylamine-glycine ligase activity K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 533.0
TLS2_k127_6956440_2 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 479.0
TLS2_k127_6956440_3 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000004218 120.0
TLS2_k127_69758_0 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003573 291.0
TLS2_k127_69758_1 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000008282 219.0
TLS2_k127_69758_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000001419 131.0
TLS2_k127_69758_3 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000001536 124.0
TLS2_k127_69758_4 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.0000000000000000000001398 100.0
TLS2_k127_6980510_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001485 188.0
TLS2_k127_6980510_1 VanZ like family - - - 0.000000000000000000000000000000000000000000000000009168 182.0
TLS2_k127_6980510_2 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000002115 130.0
TLS2_k127_6980510_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000005534 86.0
TLS2_k127_698477_0 Cytochrome c - - - 1.553e-220 700.0
TLS2_k127_698477_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 595.0
TLS2_k127_698477_11 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000001204 59.0
TLS2_k127_698477_2 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 486.0
TLS2_k127_698477_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 478.0
TLS2_k127_698477_4 DNA replication and repair protein RecF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 488.0
TLS2_k127_698477_5 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000008941 210.0
TLS2_k127_698477_6 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000001623 140.0
TLS2_k127_698477_7 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000003582 109.0
TLS2_k127_698477_8 Protein of unknown function C-terminus (DUF2399) - - - 0.0000000000000001535 93.0
TLS2_k127_698477_9 Domain of unknown function (DUF4194) - - - 0.0000000000000006949 85.0
TLS2_k127_6989904_0 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 372.0
TLS2_k127_6989904_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 327.0
TLS2_k127_6989904_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002434 286.0
TLS2_k127_6989904_3 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004103 268.0
TLS2_k127_6989904_4 CRP FNR family - - - 0.000000000000000000000000000000000000000000000000000000000000000002714 234.0
TLS2_k127_6989904_5 Peptidase family M23 - - - 0.000003583 49.0
TLS2_k127_6990145_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 4.453e-227 714.0
TLS2_k127_6990145_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 545.0
TLS2_k127_6990145_10 3D domain K02424 - - 0.00000000001053 73.0
TLS2_k127_6990145_11 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000001375 61.0
TLS2_k127_6990145_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 520.0
TLS2_k127_6990145_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 469.0
TLS2_k127_6990145_4 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 441.0
TLS2_k127_6990145_5 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 426.0
TLS2_k127_6990145_6 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000577 286.0
TLS2_k127_6990145_7 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000607 283.0
TLS2_k127_6990145_8 Protein conserved in bacteria - - - 0.00000000000000000000000004697 111.0
TLS2_k127_6990145_9 Sporulation related domain - - - 0.00000000000000000000005335 106.0
TLS2_k127_6992533_0 SMART Water Stress and Hypersensitive response - - - 0.0000000000000000000008577 100.0
TLS2_k127_6992533_1 - - - - 0.000000000000247 82.0
TLS2_k127_6992533_2 COG0457 FOG TPR repeat - - - 0.0000001244 54.0
TLS2_k127_7007910_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 403.0
TLS2_k127_7007910_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 338.0
TLS2_k127_7008613_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.736e-232 733.0
TLS2_k127_7008613_1 Transposase IS116/IS110/IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 386.0
TLS2_k127_7008613_2 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004032 253.0
TLS2_k127_7008613_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000008724 150.0
TLS2_k127_7008613_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000004646 134.0
TLS2_k127_7008613_5 Resolvase, N terminal domain - - - 0.000000000000000000000000000005384 120.0
TLS2_k127_7035539_0 Protein of unknown function (DUF1501) - - - 1.246e-240 755.0
TLS2_k127_7035539_1 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K07443 - - 8.722e-235 746.0
TLS2_k127_7035539_2 Carboxypeptidase regulatory-like domain - - - 4.912e-222 702.0
TLS2_k127_7035539_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 422.0
TLS2_k127_7035539_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 353.0
TLS2_k127_7035539_5 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 303.0
TLS2_k127_7035539_6 Beta-propeller repeat - - - 0.00000000000000000000000000000007037 144.0
TLS2_k127_7035539_7 Cytochrome c - - - 0.0000000000000000000005019 104.0
TLS2_k127_7059793_0 Transposase K07487 - - 9.456e-221 693.0
TLS2_k127_7059793_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000152 252.0
TLS2_k127_706074_0 ABC transporter transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 415.0
TLS2_k127_706074_1 alpha/beta hydrolase fold K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 309.0
TLS2_k127_706074_2 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003573 279.0
TLS2_k127_706074_3 - - - - 0.000000000000000000000000000000000000000000000000000000003997 211.0
TLS2_k127_706074_4 Protein of unknown function (DUF4230) - - - 0.00000000000000000000000000000000000000000000884 173.0
TLS2_k127_706074_5 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000001947 160.0
TLS2_k127_7066839_0 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 497.0
TLS2_k127_7066839_1 Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 471.0
TLS2_k127_7066839_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 308.0
TLS2_k127_7066839_3 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 287.0
TLS2_k127_7066839_4 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000009093 238.0
TLS2_k127_7066839_5 cyclopropane-fatty-acyl-phospholipid synthase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000009603 87.0
TLS2_k127_7066839_6 Amidohydrolase - - - 0.000001828 51.0
TLS2_k127_7067890_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003134 255.0
TLS2_k127_7075929_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 335.0
TLS2_k127_7075929_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 334.0
TLS2_k127_7075929_2 tRNA pseudouridine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 310.0
TLS2_k127_7075929_3 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
TLS2_k127_7075929_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008719 284.0
TLS2_k127_7075929_5 May nick specific sequences that contain T G mispairs resulting from m5C-deamination K07458 - - 0.00000000000000000000000000000000000000000005318 170.0
TLS2_k127_7075929_6 CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000008448 160.0
TLS2_k127_7075929_7 TM2 domain - - - 0.00000000000000000006341 98.0
TLS2_k127_7075929_8 Protein of unknown function (DUF465) - - - 0.00000000001512 67.0
TLS2_k127_7078155_0 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 329.0
TLS2_k127_7078155_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 298.0
TLS2_k127_7078155_2 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001949 257.0
TLS2_k127_7079554_0 radical SAM domain protein - - - 1.199e-301 935.0
TLS2_k127_7079554_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 604.0
TLS2_k127_7079554_2 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 564.0
TLS2_k127_7079554_3 Glycosyl hydrolase family 20, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 341.0
TLS2_k127_7079554_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000019 145.0
TLS2_k127_7079554_5 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K18907 - - 0.00000000000000000005855 104.0
TLS2_k127_7081303_0 TonB-dependent receptor - - - 2.482e-231 733.0
TLS2_k127_7081303_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 1.368e-227 724.0
TLS2_k127_7081303_10 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000083 208.0
TLS2_k127_7081303_11 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000008384 200.0
TLS2_k127_7081303_12 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000000000000000002553 139.0
TLS2_k127_7081303_13 Ribbon-helix-helix protein, copG family - - - 0.000000000000169 74.0
TLS2_k127_7081303_14 phage integrase domain protein SAM domain protein - - - 0.00005458 49.0
TLS2_k127_7081303_2 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 507.0
TLS2_k127_7081303_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 453.0
TLS2_k127_7081303_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 432.0
TLS2_k127_7081303_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 415.0
TLS2_k127_7081303_6 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 314.0
TLS2_k127_7081303_7 domain, Protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001543 294.0
TLS2_k127_7081303_8 Enolase C-terminal domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000001013 248.0
TLS2_k127_7081303_9 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000386 209.0
TLS2_k127_7110265_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.359e-243 760.0
TLS2_k127_7110265_1 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 481.0
TLS2_k127_7122302_0 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 576.0
TLS2_k127_7122302_1 peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 390.0
TLS2_k127_7122302_2 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 343.0
TLS2_k127_7122302_3 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000007755 177.0
TLS2_k127_7122302_4 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000005027 176.0
TLS2_k127_7122302_5 Putative regulatory protein - - - 0.000000006463 58.0
TLS2_k127_7123062_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 507.0
TLS2_k127_7123062_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 452.0
TLS2_k127_7123062_10 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000002543 107.0
TLS2_k127_7123062_11 Domain of unknown function (DUF4154) - - - 0.0000000000000000001623 98.0
TLS2_k127_7123062_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 430.0
TLS2_k127_7123062_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 419.0
TLS2_k127_7123062_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 395.0
TLS2_k127_7123062_5 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 392.0
TLS2_k127_7123062_6 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 366.0
TLS2_k127_7123062_7 SET domain K07117 - - 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
TLS2_k127_7123062_8 ethanolamine kinase activity K04343,K07251,K18844 - 2.7.1.72,2.7.1.89 0.0000000000000000000000000000000000000000000000000000003016 205.0
TLS2_k127_7123062_9 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000002393 156.0
TLS2_k127_712507_0 Carboxypeptidase regulatory-like domain - - - 0.0 1388.0
TLS2_k127_712507_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 609.0
TLS2_k127_712507_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 294.0
TLS2_k127_712507_3 GYD domain - - - 0.00000000000000000000000000000000000002353 146.0
TLS2_k127_712507_4 Anaphase-promoting complex, cyclosome, subunit 3 K03350 GO:0000070,GO:0000151,GO:0000152,GO:0000278,GO:0000280,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0022402,GO:0030071,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051276,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0090068,GO:0097159,GO:0098813,GO:0140014,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2001252 - 0.00000008729 63.0
TLS2_k127_7125328_0 peptidase K01415,K07386 - 3.4.24.71 3.184e-236 750.0
TLS2_k127_7125328_1 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 475.0
TLS2_k127_7125328_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.00000000000000000000000000000000000002744 150.0
TLS2_k127_7127868_0 Domain of unknown function (DUF4268) - - - 4.612e-242 773.0
TLS2_k127_7127868_1 HNH endonuclease - - - 0.00000005386 58.0
TLS2_k127_7135417_0 - - - - 1.498e-285 890.0
TLS2_k127_7135417_1 L-seryl-tRNASec selenium transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 544.0
TLS2_k127_7135417_2 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 403.0
TLS2_k127_7135417_3 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 403.0
TLS2_k127_7135417_4 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 318.0
TLS2_k127_7135417_5 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 305.0
TLS2_k127_7135417_6 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001512 267.0
TLS2_k127_7135417_7 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.00000000000000000000000000000000000000000000000000000000005702 214.0
TLS2_k127_7135417_8 Transglycosylase associated protein - - - 0.00000004294 59.0
TLS2_k127_713577_0 Resolvase domain - - - 9.386e-306 954.0
TLS2_k127_713577_1 Integrase core domain - - - 0.000000000000000000000000001019 119.0
TLS2_k127_713577_2 Winged helix-turn helix - - - 0.000000000000000008443 84.0
TLS2_k127_7151421_0 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01631,K01684 GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.1.2.21,4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 606.0
TLS2_k127_7151421_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 525.0
TLS2_k127_7151421_2 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 355.0
TLS2_k127_7151421_3 carboxylic acid catabolic process K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000003417 216.0
TLS2_k127_7151421_4 RNA recognition motif - - - 0.00000000000000000000000000000000000000000000001681 173.0
TLS2_k127_7151595_0 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 610.0
TLS2_k127_7151595_1 phosphopantetheine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 557.0
TLS2_k127_7151595_2 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 464.0
TLS2_k127_7151595_3 transferase activity, transferring glycosyl groups K16703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 432.0
TLS2_k127_7151595_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 357.0
TLS2_k127_7151595_5 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 301.0
TLS2_k127_7151595_6 hemolysin - - - 0.00000000000000000000000000000000000000000000000001126 191.0
TLS2_k127_7151595_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000001008 186.0
TLS2_k127_715391_0 PFAM Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000009459 244.0
TLS2_k127_715391_1 - - - - 0.00000000000000000000002409 108.0
TLS2_k127_715391_2 Putative esterase - - - 0.00000000000000000008128 96.0
TLS2_k127_715391_3 PFAM oxidoreductase - - - 0.0000000106 61.0
TLS2_k127_715391_4 - K07746 - - 0.000000012 60.0
TLS2_k127_715391_5 - - - - 0.00000002226 58.0
TLS2_k127_7154648_0 Histidine kinase - - - 7.8e-204 653.0
TLS2_k127_7154648_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000006443 123.0
TLS2_k127_7165251_0 Cytochrome c - - - 0.0 1128.0
TLS2_k127_7165251_1 arylsulfatase activity - - - 7.867e-238 746.0
TLS2_k127_7165251_2 - K13486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 379.0
TLS2_k127_7165251_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 338.0
TLS2_k127_7165251_4 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000121 258.0
TLS2_k127_7165251_5 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000126 153.0
TLS2_k127_7165251_6 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000001396 126.0
TLS2_k127_7169648_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1056.0
TLS2_k127_7169648_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 603.0
TLS2_k127_7169648_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 399.0
TLS2_k127_7169648_3 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000008974 197.0
TLS2_k127_7169648_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000001222 105.0
TLS2_k127_7174390_0 Protein of unknown function (DUF1501) - - - 4.32e-208 662.0
TLS2_k127_7174390_1 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 584.0
TLS2_k127_7174390_2 Mandelate racemase muconate lactonizing enzyme, N-terminal domain K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000002164 243.0
TLS2_k127_7174390_3 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000001333 131.0
TLS2_k127_7180509_0 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000002128 181.0
TLS2_k127_7180509_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000003823 119.0
TLS2_k127_7182652_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 554.0
TLS2_k127_7182652_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 308.0
TLS2_k127_7182652_2 This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003097 277.0
TLS2_k127_7182652_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000001347 177.0
TLS2_k127_7182652_4 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000001559 104.0
TLS2_k127_7182652_5 Cupin domain - - - 0.000000000000000201 79.0
TLS2_k127_7182652_6 Cupin domain - - - 0.0000000000000002601 81.0
TLS2_k127_718610_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 497.0
TLS2_k127_718610_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000001516 175.0
TLS2_k127_718610_2 Cytochrome C oxidase, cbb3-type, subunit III K02305 - - 0.000000002629 63.0
TLS2_k127_718610_3 Belongs to the peptidase M50B family - - - 0.00000397 49.0
TLS2_k127_7199024_0 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 5.946e-219 690.0
TLS2_k127_7199024_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 518.0
TLS2_k127_7199024_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 432.0
TLS2_k127_7199024_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004598 299.0
TLS2_k127_7199024_4 PFAM PPIC-type K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001136 258.0
TLS2_k127_7199024_5 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007553 238.0
TLS2_k127_7199024_6 response regulator, receiver K02485 - - 0.000000000000000000000001604 108.0
TLS2_k127_7199024_7 - - - - 0.0000002951 60.0
TLS2_k127_7199024_8 - - - - 0.00001318 55.0
TLS2_k127_7206154_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 468.0
TLS2_k127_7206154_1 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 402.0
TLS2_k127_7206154_2 helix_turn _helix lactose operon repressor K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 338.0
TLS2_k127_7207943_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 589.0
TLS2_k127_7207943_1 tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 443.0
TLS2_k127_7207943_2 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000002512 232.0
TLS2_k127_7207943_3 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000001836 134.0
TLS2_k127_7215529_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 571.0
TLS2_k127_7215529_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 368.0
TLS2_k127_7215529_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 359.0
TLS2_k127_7215529_3 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 300.0
TLS2_k127_7215529_4 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000002943 143.0
TLS2_k127_7215529_5 NUDIX domain - - - 0.00000000000000000000000000001807 124.0
TLS2_k127_7215529_6 Sulfatase - - - 0.00000000003266 66.0
TLS2_k127_7216204_0 PFAM glycoside hydrolase, family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 476.0
TLS2_k127_7216204_1 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 454.0
TLS2_k127_7216204_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 374.0
TLS2_k127_7216204_3 PFAM Class II aldolase K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 313.0
TLS2_k127_7216204_4 PFAM Carbohydrate kinase K00853 - 2.7.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001198 277.0
TLS2_k127_7216204_5 Domain of unknown function (DUF5060) - - - 0.0000000000000000000000000000000000000000000000000000000000000002663 226.0
TLS2_k127_7216204_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000004511 152.0
TLS2_k127_7216204_7 Glycosyltransferase like family 2 K07011 - - 0.000000000000000003481 92.0
TLS2_k127_7226861_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 336.0
TLS2_k127_7226861_1 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003239 257.0
TLS2_k127_7226861_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000009429 53.0
TLS2_k127_7230019_0 COG5433 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 365.0
TLS2_k127_7233996_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 522.0
TLS2_k127_7258681_0 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 443.0
TLS2_k127_7258681_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 336.0
TLS2_k127_7258681_2 myo-inosose-2 dehydratase activity K06606 - 5.3.99.11 0.00000000000000001974 86.0
TLS2_k127_7258681_3 pathogenesis - - - 0.00004346 52.0
TLS2_k127_7260853_0 PhoPQ-activated pathogenicity-related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 546.0
TLS2_k127_7260853_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 498.0
TLS2_k127_7260853_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000001285 203.0
TLS2_k127_7260853_3 - - - - 0.000000000000000000000000000284 124.0
TLS2_k127_7260853_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000003436 102.0
TLS2_k127_7260853_6 - - - - 0.000000012 60.0
TLS2_k127_7260853_7 - - - - 0.00007901 46.0
TLS2_k127_7272482_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 574.0
TLS2_k127_7272482_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 310.0
TLS2_k127_7273345_0 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 571.0
TLS2_k127_7273345_1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 517.0
TLS2_k127_7273345_2 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 318.0
TLS2_k127_7273345_3 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.00000000000000000000000000000000000000000000000000000000000002999 215.0
TLS2_k127_7273345_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000001229 195.0
TLS2_k127_7273345_5 BNR repeat-like domain K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000001172 187.0
TLS2_k127_7273345_6 Peptidase M56 - - - 0.0000000000000000000000000000000003384 145.0
TLS2_k127_7273345_7 Peptidase M56 - - - 0.000003179 53.0
TLS2_k127_7277303_0 Putative glucoamylase - - - 0.0 1324.0
TLS2_k127_7277303_1 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 1.063e-244 766.0
TLS2_k127_7291933_0 Multicopper oxidase - - - 0.0 1010.0
TLS2_k127_7291933_1 response regulator - - - 1.698e-218 685.0
TLS2_k127_7291933_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 563.0
TLS2_k127_7291933_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 561.0
TLS2_k127_7291933_4 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 445.0
TLS2_k127_7291933_5 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 391.0
TLS2_k127_7291933_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 365.0
TLS2_k127_7291933_7 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000002511 222.0
TLS2_k127_7291933_8 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000002757 136.0
TLS2_k127_7297961_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1039.0
TLS2_k127_7297961_1 Phytochrome central region domain protein - - - 1.041e-255 809.0
TLS2_k127_7297961_10 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 324.0
TLS2_k127_7297961_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 299.0
TLS2_k127_7297961_12 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 295.0
TLS2_k127_7297961_13 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 298.0
TLS2_k127_7297961_14 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001528 297.0
TLS2_k127_7297961_15 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004872 293.0
TLS2_k127_7297961_16 GHMP kinases C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001052 274.0
TLS2_k127_7297961_17 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000007751 241.0
TLS2_k127_7297961_18 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000006723 237.0
TLS2_k127_7297961_19 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000003817 218.0
TLS2_k127_7297961_2 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 572.0
TLS2_k127_7297961_20 MafB19-like deaminase - - - 0.000000000000000000000000000000000000000000000000002342 195.0
TLS2_k127_7297961_21 Phosphotransferase enzyme family K06979 - - 0.000000000000000000000000000000000000000000003316 169.0
TLS2_k127_7297961_22 - - - - 0.00000000000000000000000000000000000000000004983 166.0
TLS2_k127_7297961_23 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000001269 157.0
TLS2_k127_7297961_24 DinB superfamily - - - 0.0000000000000000000000000000000000001531 147.0
TLS2_k127_7297961_25 Heme oxygenase - - - 0.0000000000000000000000000000001617 131.0
TLS2_k127_7297961_26 YCII-related domain - - - 0.00000000000000000000000000000216 123.0
TLS2_k127_7297961_27 phosphorelay signal transduction system - - - 0.0000000000000000000000000002122 121.0
TLS2_k127_7297961_28 - - - - 0.0000000000000000000001441 106.0
TLS2_k127_7297961_29 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000008021 96.0
TLS2_k127_7297961_3 COG3119 Arylsulfatase A K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 471.0
TLS2_k127_7297961_4 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 445.0
TLS2_k127_7297961_5 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009866 439.0
TLS2_k127_7297961_6 Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 404.0
TLS2_k127_7297961_7 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 353.0
TLS2_k127_7297961_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 321.0
TLS2_k127_7297961_9 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 317.0
TLS2_k127_7311139_0 GMC oxidoreductase K03333 - 1.1.3.6 5.861e-273 848.0
TLS2_k127_7311139_1 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 610.0
TLS2_k127_7311139_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 449.0
TLS2_k127_7311839_0 TonB-dependent receptor - - - 1.753e-268 863.0
TLS2_k127_7311839_1 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 519.0
TLS2_k127_7311839_2 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 477.0
TLS2_k127_7311839_3 alkaline phosphatase D K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 347.0
TLS2_k127_7311839_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 313.0
TLS2_k127_7311839_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000004103 81.0
TLS2_k127_7311839_6 PhoD-like phosphatase - - - 0.0000004166 57.0
TLS2_k127_7311839_7 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00001324 50.0
TLS2_k127_7313426_0 iron dependent repressor K02003,K02565,K15545 - - 7.064e-217 686.0
TLS2_k127_7313426_1 Transposase K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 459.0
TLS2_k127_7313426_2 cell redox homeostasis - - - 0.0000000000000000000000000000001096 127.0
TLS2_k127_7316134_0 phosphoglucosamine mutase activity K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 1.305e-201 643.0
TLS2_k127_7316134_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 307.0
TLS2_k127_7316134_2 Ribosomal protein L11/L12 K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001496 254.0
TLS2_k127_7316134_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000003193 98.0
TLS2_k127_7316134_4 structural constituent of ribosome K02913 - - 0.00000000000000000002262 90.0
TLS2_k127_7316134_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000876 83.0
TLS2_k127_7316134_6 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000001495 81.0
TLS2_k127_7316134_7 Methyltransferase domain - - - 0.0000000375 64.0
TLS2_k127_7325087_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 9.35e-201 639.0
TLS2_k127_7325087_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000003801 231.0
TLS2_k127_7337614_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 524.0
TLS2_k127_7337614_1 Cobalamin-independent synthase, Catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 492.0
TLS2_k127_7337614_2 Involved in the tonB-independent uptake of proteins K01730 - 4.2.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 482.0
TLS2_k127_7337614_3 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000426 193.0
TLS2_k127_7337614_4 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000007045 159.0
TLS2_k127_7337614_5 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000009575 127.0
TLS2_k127_7337614_6 - - - - 0.000000000000000000000000000006359 121.0
TLS2_k127_7337614_7 Carboxypeptidase regulatory-like domain - - - 0.00000000001387 75.0
TLS2_k127_7337640_0 - - - - 0.0000000000000000000003913 108.0
TLS2_k127_7337640_1 Addiction module toxin, RelE StbE - - - 0.000000000000000000002104 96.0
TLS2_k127_7337640_2 CAAX protease self-immunity K07052 - - 0.000000000000000000002699 100.0
TLS2_k127_7340704_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 436.0
TLS2_k127_7340704_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 370.0
TLS2_k127_7347265_0 PFAM TonB-dependent Receptor Plug - - - 0.0 1253.0
TLS2_k127_7347265_1 MacB-like periplasmic core domain - - - 1.04e-311 976.0
TLS2_k127_7347265_10 helix_turn _helix lactose operon repressor K05499 - - 0.00000000000000002345 85.0
TLS2_k127_7347265_11 WD domain, G-beta repeat - - - 0.000255 47.0
TLS2_k127_7347265_2 Protein of unknown function (DUF1587) - - - 6.286e-269 844.0
TLS2_k127_7347265_3 Protein of unknown function (DUF1552) - - - 1.376e-248 772.0
TLS2_k127_7347265_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 490.0
TLS2_k127_7347265_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000001371 234.0
TLS2_k127_7347265_6 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000009792 214.0
TLS2_k127_7347265_7 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000001165 200.0
TLS2_k127_7347265_8 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000004908 170.0
TLS2_k127_7347265_9 polysaccharide export K01991,K16552 - - 0.00000000000000000000000002524 115.0
TLS2_k127_7349312_0 -O-antigen K02847,K13009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 439.0
TLS2_k127_7349312_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003001 272.0
TLS2_k127_7349312_2 extracellular polysaccharide biosynthetic process K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000006857 213.0
TLS2_k127_7349312_3 polysaccharide export K01991,K16552 - - 0.00000000000000000000000000000000000001655 164.0
TLS2_k127_7349312_4 Major facilitator superfamily - - - 0.0000003167 63.0
TLS2_k127_7350533_0 Carboxypeptidase regulatory-like domain - - - 3.284e-213 678.0
TLS2_k127_7350533_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 319.0
TLS2_k127_7350533_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000007599 229.0
TLS2_k127_7355890_0 Carboxypeptidase regulatory-like domain - - - 4.836e-284 897.0
TLS2_k127_7359602_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1270.0
TLS2_k127_7359602_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1236.0
TLS2_k127_7359602_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 380.0
TLS2_k127_7359602_3 hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 353.0
TLS2_k127_7359602_4 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 309.0
TLS2_k127_7359602_5 PFAM Cold-shock K03704 - - 0.000000000000000000000000000003619 119.0
TLS2_k127_7359602_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K18917 - 1.20.4.3 0.00000000000000000000006187 103.0
TLS2_k127_7359602_7 - - - - 0.0000000007846 66.0
TLS2_k127_7364734_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 595.0
TLS2_k127_7364734_1 Beta-lactamase K18988 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 312.0
TLS2_k127_7364734_2 NACHT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002422 239.0
TLS2_k127_7364734_3 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000000000000000000003323 201.0
TLS2_k127_7366055_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.223e-256 812.0
TLS2_k127_7366055_1 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 616.0
TLS2_k127_7366055_2 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007999 258.0
TLS2_k127_7366055_3 MlrC C-terminus - - - 0.0000000000000000000000006394 106.0
TLS2_k127_7367994_0 Protein of unknown function (DUF1501) - - - 1.124e-242 758.0
TLS2_k127_7367994_1 Protein of unknown function (DUF1549) - - - 0.000000000000000000000000000000137 127.0
TLS2_k127_7367994_2 CopG antitoxin of type II toxin-antitoxin system - - - 0.0007619 44.0
TLS2_k127_7371716_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 1.177e-226 712.0
TLS2_k127_7371716_1 Protein of unknown function, DUF255 K06888 - - 1.506e-200 640.0
TLS2_k127_7371716_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000003581 93.0
TLS2_k127_7371716_2 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 507.0
TLS2_k127_7371716_3 gluconolactonase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 491.0
TLS2_k127_7371716_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 420.0
TLS2_k127_7371716_5 methyltransferase K20421 - 2.1.1.303 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 312.0
TLS2_k127_7371716_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 286.0
TLS2_k127_7371716_7 Redoxin K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001856 235.0
TLS2_k127_7371716_8 Bacterial-like globin K06886 - - 0.000000000000000000000000000000004873 132.0
TLS2_k127_7371716_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001689 116.0
TLS2_k127_7371901_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 344.0
TLS2_k127_7371901_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 355.0
TLS2_k127_7371901_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003143 251.0
TLS2_k127_7371901_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000001479 177.0
TLS2_k127_7371901_4 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000002463 141.0
TLS2_k127_7371901_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000019 105.0
TLS2_k127_7371901_7 Photosynthetic reaction centre cytochrome C subunit - - - 0.0001227 51.0
TLS2_k127_7382470_0 Protein of unknown function (DUF1553) - - - 1.121e-198 640.0
TLS2_k127_7382470_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 497.0
TLS2_k127_7382470_2 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 462.0
TLS2_k127_7383668_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 374.0
TLS2_k127_7383668_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 344.0
TLS2_k127_738382_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 347.0
TLS2_k127_738382_1 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000003301 204.0
TLS2_k127_738382_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000009638 154.0
TLS2_k127_7390459_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 342.0
TLS2_k127_7390459_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 310.0
TLS2_k127_7390459_2 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 316.0
TLS2_k127_7390459_3 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000005845 233.0
TLS2_k127_7390459_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006671 253.0
TLS2_k127_7390459_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00004781 50.0
TLS2_k127_7390489_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 340.0
TLS2_k127_7390489_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 293.0
TLS2_k127_7390489_2 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 296.0
TLS2_k127_7390489_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006126 278.0
TLS2_k127_7390489_4 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 272.0
TLS2_k127_7390489_5 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000000000000000000001205 153.0
TLS2_k127_7395457_0 3-demethylubiquinone-9 3-O-methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 6.303e-291 905.0
TLS2_k127_7395457_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 4.648e-200 628.0
TLS2_k127_7395457_2 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 388.0
TLS2_k127_7395457_3 PFAM peptidase T2 asparaginase 2 K01444 - 3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000009263 218.0
TLS2_k127_7395457_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000005059 151.0
TLS2_k127_7396563_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1103.0
TLS2_k127_7396563_1 Acyclic terpene utilisation family protein AtuA - - - 2.316e-217 681.0
TLS2_k127_7396563_2 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 406.0
TLS2_k127_7396563_3 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 334.0
TLS2_k127_7396563_4 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000001188 186.0
TLS2_k127_7396563_5 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000008132 175.0
TLS2_k127_7396563_6 - - - - 0.000000000000000000000000000000000000000004485 158.0
TLS2_k127_7396690_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 482.0
TLS2_k127_7396690_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 417.0
TLS2_k127_7396690_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 390.0
TLS2_k127_7396690_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002391 265.0
TLS2_k127_7396690_4 PFAM Glycosyl transferase, family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000002064 109.0
TLS2_k127_7396690_5 monooxygenase activity - - - 0.0000000000000745 76.0
TLS2_k127_7396690_6 SnoaL-like domain K06893 - - 0.000000000004529 77.0
TLS2_k127_7402381_0 PFAM Integrase catalytic - - - 2.064e-253 789.0
TLS2_k127_7402381_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 411.0
TLS2_k127_7402381_2 - - - - 0.00000000001711 73.0
TLS2_k127_7402381_3 SpoVT / AbrB like domain - - - 0.00002366 51.0
TLS2_k127_7403082_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 353.0
TLS2_k127_7403082_1 PFAM Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 333.0
TLS2_k127_7403082_2 Transglutaminase/protease-like homologues K01406 - 3.4.24.40 0.0000000000006781 78.0
TLS2_k127_7403082_3 Histidine kinase K07675 - 2.7.13.3 0.00001362 51.0
TLS2_k127_7421698_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000368 305.0
TLS2_k127_7421698_1 Tetratricopeptide repeat - - - 0.00000000000414 76.0
TLS2_k127_7427055_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 447.0
TLS2_k127_7427055_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 368.0
TLS2_k127_7427055_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 364.0
TLS2_k127_7427055_3 pathogenesis K01460 - 3.5.1.78,6.3.1.8 0.000000000000000000000000000000000000000001549 172.0
TLS2_k127_7427055_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000002212 84.0
TLS2_k127_7427055_5 DDE superfamily endonuclease - - - 0.000008339 49.0
TLS2_k127_744661_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 4.046e-206 644.0
TLS2_k127_744661_1 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 403.0
TLS2_k127_744661_2 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 389.0
TLS2_k127_744661_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 351.0
TLS2_k127_744661_4 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000109 212.0
TLS2_k127_744661_5 Uncharacterized ACR, COG1430 - - - 0.00000000000000000000000000000000002325 140.0
TLS2_k127_744661_6 Helix-turn-helix domain - - - 0.000000000000000000000000009498 116.0
TLS2_k127_7447637_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1056.0
TLS2_k127_7447637_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 614.0
TLS2_k127_7447637_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 447.0
TLS2_k127_7447637_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 332.0
TLS2_k127_7447637_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003899 277.0
TLS2_k127_7447637_5 protein deglycation K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005276 273.0
TLS2_k127_7447637_6 candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238 K18197 - 4.2.2.23 0.0000000000000000000000000000000000000000000000000000001561 219.0
TLS2_k127_7447637_7 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000001497 137.0
TLS2_k127_7447637_8 Evidence 4 Homologs of previously reported genes of - - - 0.00000006339 61.0
TLS2_k127_7460280_0 Cytochrome c - - - 0.0 1146.0
TLS2_k127_7460280_1 Protein of unknown function (DUF1501) - - - 9.979e-253 787.0
TLS2_k127_7460280_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 2.016e-207 662.0
TLS2_k127_7460280_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 420.0
TLS2_k127_7460280_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 383.0
TLS2_k127_7460280_5 myo-inosose-2 dehydratase activity K03335,K15652 - 4.2.1.118,4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000001942 234.0
TLS2_k127_7468694_0 Transposase - - - 5.87e-207 663.0
TLS2_k127_7468694_1 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000005042 121.0
TLS2_k127_7471326_0 TonB-dependent Receptor Plug Domain - - - 0.0 1050.0
TLS2_k127_7471326_1 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 294.0
TLS2_k127_749132_0 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.0000000000000000000000000000000000008448 155.0
TLS2_k127_750060_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1393.0
TLS2_k127_750060_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.63e-228 725.0
TLS2_k127_750060_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 488.0
TLS2_k127_750060_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000003255 229.0
TLS2_k127_750060_4 KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000000000525 199.0
TLS2_k127_753318_0 amino acid K03294 - - 8.693e-205 648.0
TLS2_k127_753318_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 610.0
TLS2_k127_753318_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 371.0
TLS2_k127_753318_3 ABC transporter substrate-binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 329.0
TLS2_k127_753318_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002907 284.0
TLS2_k127_753318_5 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000003814 240.0
TLS2_k127_753318_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000001602 203.0
TLS2_k127_753318_7 Extracellular repeat protein, HAF family - - - 0.00000000000000000000000000000000004548 151.0
TLS2_k127_753318_8 Dicarboxylate transporter 2.1 K03319 GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005313,GO:0005326,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009064,GO:0009507,GO:0009526,GO:0009534,GO:0009536,GO:0009579,GO:0009605,GO:0009607,GO:0009624,GO:0009941,GO:0009987,GO:0015075,GO:0015131,GO:0015140,GO:0015171,GO:0015172,GO:0015179,GO:0015238,GO:0015318,GO:0015556,GO:0015711,GO:0015729,GO:0015740,GO:0015743,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016020,GO:0019676,GO:0019740,GO:0019752,GO:0022857,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034220,GO:0042221,GO:0042493,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055085,GO:0071423,GO:0071702,GO:0071704,GO:0071705,GO:0098656,GO:1901564,GO:1901605,GO:1902356,GO:1902475,GO:1903825,GO:1905039 - 0.000000003954 62.0
TLS2_k127_753318_9 Sodium:sulfate symporter transmembrane region K03319 - - 0.0000002514 55.0
TLS2_k127_758807_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 579.0
TLS2_k127_758807_1 arylsulfatase activity K01130,K01134 - 3.1.6.1,3.1.6.8 0.000000000000000000000000000000000000000000000000000000000000006577 220.0
TLS2_k127_758807_2 helix_turn_helix, Lux Regulon - - - 0.0000000001587 63.0
TLS2_k127_758807_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00001036 54.0
TLS2_k127_762121_0 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 540.0
TLS2_k127_762121_1 secretory pathway K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 482.0
TLS2_k127_762121_2 protein transport across the cell outer membrane K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 441.0
TLS2_k127_762121_3 Pilus assembly protein K02461,K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 380.0
TLS2_k127_762121_4 protein secretion K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000124 251.0
TLS2_k127_762121_6 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000003003 205.0
TLS2_k127_762121_7 general secretion pathway protein K02246,K02456,K02458 - - 0.0000000000000000000000000000000000000000000000000004964 190.0
TLS2_k127_762121_9 general secretion pathway protein K02456,K02458,K02459,K10927 - - 0.000000000000000000000000000000002849 138.0
TLS2_k127_76441_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 590.0
TLS2_k127_76441_1 YCII-related domain K09780 - - 0.000006783 49.0
TLS2_k127_765231_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 404.0
TLS2_k127_765231_1 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000267 285.0
TLS2_k127_765231_2 PhoQ Sensor - - - 0.0000000000000001651 91.0
TLS2_k127_770313_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1259.0
TLS2_k127_770313_1 acetylesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 553.0
TLS2_k127_770313_2 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 558.0
TLS2_k127_770313_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 342.0
TLS2_k127_770313_4 Inosine-uridine preferring nucleoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 292.0
TLS2_k127_770313_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006752 297.0
TLS2_k127_770313_6 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000007115 181.0
TLS2_k127_770313_7 restriction endonuclease - - - 0.0009869 44.0
TLS2_k127_771718_0 protocatechuate 3,4-dioxygenase activity - - - 2.493e-212 696.0
TLS2_k127_771718_1 Anti-sigma factor - - - 0.000000000000000000000000000000000000000000000000000000006108 218.0
TLS2_k127_772524_0 ABC-type proline glycine betaine transport K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 302.0
TLS2_k127_772524_1 ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 311.0
TLS2_k127_772524_2 glycine betaine transport K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 265.0
TLS2_k127_772524_3 secondary active p-aminobenzoyl-glutamate transmembrane transporter activity K12942 - - 0.00000000000000000000000000000000000000000000000000000001412 199.0
TLS2_k127_775261_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 336.0
TLS2_k127_775261_1 SPTR CopG domain protein DNA-binding domain protein - - - 0.00000000000000000000000000000001053 128.0
TLS2_k127_775261_2 efflux transmembrane transporter activity - - - 0.000000000000000000001168 97.0
TLS2_k127_78602_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 446.0
TLS2_k127_78602_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 394.0
TLS2_k127_78602_2 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 313.0
TLS2_k127_791959_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 380.0
TLS2_k127_791959_1 with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000004818 229.0
TLS2_k127_793810_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1318.0
TLS2_k127_793810_1 von Willebrand factor (vWF) type A domain - - - 0.00002815 49.0
TLS2_k127_801872_0 PFAM oxidoreductase domain protein - - - 9.754e-217 679.0
TLS2_k127_801872_1 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 550.0
TLS2_k127_801872_2 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 306.0
TLS2_k127_806324_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 1.651e-255 803.0
TLS2_k127_806324_1 AMP binding K06149 - - 0.000005002 50.0
TLS2_k127_806324_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0001508 50.0
TLS2_k127_806324_3 Universal stress protein family - - - 0.0007844 42.0
TLS2_k127_807356_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 432.0
TLS2_k127_807356_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 295.0
TLS2_k127_807356_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000002251 172.0
TLS2_k127_807356_11 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000004581 158.0
TLS2_k127_807356_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000006075 153.0
TLS2_k127_807356_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000001001 136.0
TLS2_k127_807356_14 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000003986 97.0
TLS2_k127_807356_15 Ribosomal protein L30 K02907 - - 0.00000000000000000129 94.0
TLS2_k127_807356_16 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000003471 87.0
TLS2_k127_807356_17 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001564 85.0
TLS2_k127_807356_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 291.0
TLS2_k127_807356_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003292 269.0
TLS2_k127_807356_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003224 239.0
TLS2_k127_807356_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000002214 224.0
TLS2_k127_807356_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000001031 216.0
TLS2_k127_807356_7 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000001891 197.0
TLS2_k127_807356_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000001997 187.0
TLS2_k127_807356_9 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000002155 182.0
TLS2_k127_811486_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 572.0
TLS2_k127_811486_1 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 494.0
TLS2_k127_811486_11 PFAM Integrase catalytic - - - 0.00000000000000000000000000002236 130.0
TLS2_k127_811486_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000004411 118.0
TLS2_k127_811486_13 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000006158 86.0
TLS2_k127_811486_14 - - - - 0.00005449 52.0
TLS2_k127_811486_2 ParB-like nuclease domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 361.0
TLS2_k127_811486_3 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 311.0
TLS2_k127_811486_4 Integrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006595 290.0
TLS2_k127_811486_5 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000436 275.0
TLS2_k127_811486_6 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003461 258.0
TLS2_k127_811486_7 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004121 254.0
TLS2_k127_811486_8 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000002475 231.0
TLS2_k127_811486_9 Bacterial dnaA protein - - - 0.0000000000000000000000000000000000003901 140.0
TLS2_k127_815268_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 363.0
TLS2_k127_815268_1 pfam abc-3 K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000003405 237.0
TLS2_k127_815268_2 Trm112p-like protein - - - 0.00000000000000000001843 93.0
TLS2_k127_830463_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 456.0
TLS2_k127_830463_1 DinB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009541 275.0
TLS2_k127_830463_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000001717 199.0
TLS2_k127_830463_3 Gmc oxidoreductase - - - 0.0000000000000000000000000000000000000000000000003003 184.0
TLS2_k127_830463_4 lytic transglycosylase activity - - - 0.0000000000000000000000000000000002295 143.0
TLS2_k127_830463_5 Rod binding protein - - - 0.0000000000001601 78.0
TLS2_k127_830463_6 flagellar protein FliS K02422 - - 0.0000000000009037 73.0
TLS2_k127_830463_7 Chaperone for flagella basal body P-ring formation K02386 - - 0.00001003 51.0
TLS2_k127_833153_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 320.0
TLS2_k127_833153_1 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006731 262.0
TLS2_k127_833153_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001694 260.0
TLS2_k127_833153_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000008348 124.0
TLS2_k127_833153_4 COG2223 Nitrate nitrite transporter K02575 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000001056 81.0
TLS2_k127_833153_5 Protein of unknown function (DUF423) - - - 0.00000000000001256 75.0
TLS2_k127_833153_6 PrcB C-terminal - - - 0.000001146 57.0
TLS2_k127_834507_0 filamentation induced by cAMP protein Fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 349.0
TLS2_k127_834507_1 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000006677 155.0
TLS2_k127_834507_2 Fic/DOC family K07341 - - 0.00000000000000000000000000697 113.0
TLS2_k127_834507_3 PFAM SpoVT AbrB K07172,K18842 - - 0.000000004147 63.0
TLS2_k127_837743_0 protein, phage tail-like region - - - 6.584e-256 814.0
TLS2_k127_837743_1 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 643.0
TLS2_k127_837743_2 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 466.0
TLS2_k127_837743_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 349.0
TLS2_k127_837743_4 Baseplate assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001721 274.0
TLS2_k127_837743_5 - - - - 0.000000000000000000000000000000000000000007294 156.0
TLS2_k127_837743_6 positive regulation of growth rate - GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - 0.000000000000000000000000000006561 119.0
TLS2_k127_837743_7 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000039 113.0
TLS2_k127_84616_0 transport - - - 3.397e-296 937.0
TLS2_k127_84616_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 468.0
TLS2_k127_84616_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 297.0
TLS2_k127_860775_0 PFAM Polysulphide reductase, NrfD - - - 1.403e-226 713.0
TLS2_k127_860775_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 563.0
TLS2_k127_860775_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 473.0
TLS2_k127_860775_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008414 254.0
TLS2_k127_860775_4 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000001032 225.0
TLS2_k127_860775_5 - - - - 0.0000000000000008657 86.0
TLS2_k127_861045_0 Carboxypeptidase regulatory-like domain - - - 4.358e-245 781.0
TLS2_k127_861045_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 321.0
TLS2_k127_872332_0 succinate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 331.0
TLS2_k127_872332_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 330.0
TLS2_k127_872332_2 GntR family transcriptional regulator K02103 - - 0.00000000000000000000000000000000000000003375 166.0
TLS2_k127_872332_3 Integrase core domain - - - 0.00000000000614 72.0
TLS2_k127_872332_4 YjbR - - - 0.000001603 56.0
TLS2_k127_876844_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 308.0
TLS2_k127_876844_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001621 264.0
TLS2_k127_876844_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002949 232.0
TLS2_k127_876844_3 May be involved in cell division K05803 - - 0.0000000000000000000000000000002388 139.0
TLS2_k127_897895_0 Carboxypeptidase regulatory-like domain - - - 5.471e-308 977.0
TLS2_k127_897895_1 BNR repeat-containing family member - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 342.0
TLS2_k127_897895_2 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004744 254.0
TLS2_k127_897895_3 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000000000000000000124 226.0
TLS2_k127_897895_4 CYTH K05873 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000187 198.0
TLS2_k127_897895_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000004603 124.0
TLS2_k127_897895_7 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000009973 88.0
TLS2_k127_911599_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 572.0
TLS2_k127_911599_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 569.0
TLS2_k127_911599_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 512.0
TLS2_k127_911599_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 470.0
TLS2_k127_911599_4 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 387.0
TLS2_k127_911599_5 Fibronectin type III domain protein - - - 0.0000000000000000000000000000000000000000000000008748 184.0
TLS2_k127_911599_7 Beta-propeller repeat - - - 0.0000000144 68.0
TLS2_k127_926506_0 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 388.0
TLS2_k127_926506_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 338.0
TLS2_k127_926506_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 329.0
TLS2_k127_926506_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 275.0
TLS2_k127_926506_4 receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001371 284.0
TLS2_k127_926506_5 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000006069 152.0
TLS2_k127_926506_7 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000003818 138.0
TLS2_k127_926506_8 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.000000000000000000000000000000001766 133.0
TLS2_k127_926506_9 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000000000000001078 102.0
TLS2_k127_927289_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 538.0
TLS2_k127_927289_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 511.0
TLS2_k127_927289_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 458.0
TLS2_k127_927289_3 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 348.0
TLS2_k127_927289_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 331.0
TLS2_k127_927289_5 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.000000000000000000000000000000001427 132.0
TLS2_k127_927289_6 methyltransferase - - - 0.000000000000000001521 89.0
TLS2_k127_927532_0 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 482.0
TLS2_k127_927532_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002664 273.0
TLS2_k127_927532_2 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000001643 214.0
TLS2_k127_930922_0 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1756.0
TLS2_k127_930922_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.247e-320 995.0
TLS2_k127_930922_10 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000001152 211.0
TLS2_k127_930922_11 thiolester hydrolase activity K07000 - - 0.000000000000000000000000000000000000000000000000000000005204 207.0
TLS2_k127_930922_12 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000002828 193.0
TLS2_k127_930922_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000001607 183.0
TLS2_k127_930922_14 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000001709 176.0
TLS2_k127_930922_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000001284 135.0
TLS2_k127_930922_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000007959 95.0
TLS2_k127_930922_2 Beta-eliminating lyase K01667 - 4.1.99.1 5.301e-222 697.0
TLS2_k127_930922_3 family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 560.0
TLS2_k127_930922_4 SMART glycoside hydrolase family 29 (alpha-L- fucosidase) K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 450.0
TLS2_k127_930922_5 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 366.0
TLS2_k127_930922_6 Belongs to the helicase family. UvrD subfamily K03169,K16899 - 3.6.4.12,5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 362.0
TLS2_k127_930922_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002822 282.0
TLS2_k127_930922_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003019 244.0
TLS2_k127_930922_9 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001904 223.0
TLS2_k127_935507_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 376.0
TLS2_k127_935507_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001133 263.0
TLS2_k127_935507_2 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000001266 201.0
TLS2_k127_93578_0 metallocarboxypeptidase activity K14054 - - 6.363e-215 677.0
TLS2_k127_93578_1 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 456.0
TLS2_k127_93578_2 mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 306.0
TLS2_k127_93578_3 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009332 286.0
TLS2_k127_93578_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000004964 113.0
TLS2_k127_957423_0 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 373.0
TLS2_k127_957423_1 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000000001606 209.0
TLS2_k127_957423_2 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000001677 176.0
TLS2_k127_957423_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000005088 97.0
TLS2_k127_957423_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0009013 48.0
TLS2_k127_958537_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 1.428e-278 870.0
TLS2_k127_958537_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 6.516e-267 835.0
TLS2_k127_958537_10 - - - - 0.0000000000000000004725 93.0
TLS2_k127_958537_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 437.0
TLS2_k127_958537_3 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 323.0
TLS2_k127_958537_4 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 320.0
TLS2_k127_958537_5 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000003841 231.0
TLS2_k127_958537_6 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000002196 209.0
TLS2_k127_958537_7 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000005269 157.0
TLS2_k127_958537_8 Superoxide dismutase K04565 - 1.15.1.1 0.00000000000000000000000000000000003572 148.0
TLS2_k127_958537_9 PQQ-dependent catabolism-associated beta-propeller protein - - - 0.0000000000000000000000000000000001297 147.0
TLS2_k127_965741_0 arsenical-resistance protein K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 496.0
TLS2_k127_965741_1 Arsenite-activated ATPase (ArsA) K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 387.0
TLS2_k127_965741_2 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000009834 154.0
TLS2_k127_965741_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000295 151.0
TLS2_k127_98460_0 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 304.0
TLS2_k127_98460_1 WD40-like Beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000001727 216.0
TLS2_k127_98460_2 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000001761 190.0
TLS2_k127_98460_3 - - - - 0.0007058 43.0
TLS2_k127_988651_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 1.527e-240 754.0
TLS2_k127_988651_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000004005 149.0
TLS2_k127_997119_0 COG5433 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 481.0
TLS2_k127_997119_1 PFAM IS66 Orf2 like protein K07484 - - 0.000000000000000000000001299 108.0
TLS2_k127_997119_3 PFAM IS1 transposase - - - 0.000108 48.0