Overview

ID MAG04043
Name TLS3_bin.2
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhodobacterales
Family Rhodobacteraceae
Genus Amaricoccus
Species
Assembly information
Completeness (%) 82.68
Contamination (%) 6.08
GC content (%) 73.0
N50 (bp) 5,648
Genome size (bp) 2,929,013

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3076

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1004705_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 1.373e-239 745.0
TLS3_k127_1004705_1 Protein of unknown function (DUF2842) - - - 0.00000000000000001258 86.0
TLS3_k127_1004705_2 cytochrome P450 - - - 0.0001472 51.0
TLS3_k127_1042435_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 327.0
TLS3_k127_1042435_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 335.0
TLS3_k127_1042435_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003331 278.0
TLS3_k127_1042435_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000001099 211.0
TLS3_k127_1042435_4 Outer membrane protein (OmpH-like) - - - 0.000000000000000001269 94.0
TLS3_k127_1047835_0 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 303.0
TLS3_k127_1047835_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000004785 136.0
TLS3_k127_1047835_2 Phospholipase lecithinase hemolysin - - - 0.000000000000000000000000000001947 132.0
TLS3_k127_1053414_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 1.423e-270 840.0
TLS3_k127_1053414_1 GMC oxidoreductase K00108 - 1.1.99.1 1.818e-254 796.0
TLS3_k127_1053414_2 Aldo/keto reductase family K06222 - 1.1.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 384.0
TLS3_k127_1053414_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 349.0
TLS3_k127_1053414_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 327.0
TLS3_k127_1053414_5 Protein of unknown function (DUF993) - - - 0.0000000000000000000000000000000000000000000000000000001245 199.0
TLS3_k127_1053414_6 PFAM regulatory protein LysR - - - 0.0001277 49.0
TLS3_k127_1062557_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1222.0
TLS3_k127_1062557_1 Putative amidoligase enzyme (DUF2126) - - - 0.0 1007.0
TLS3_k127_1062557_2 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 486.0
TLS3_k127_1062557_3 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 479.0
TLS3_k127_1062557_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 399.0
TLS3_k127_1062557_5 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.00000000000000000000000000000000000000000000000000000000000000000000001106 251.0
TLS3_k127_1062557_6 PFAM Fe-S metabolism associated K02426 - - 0.0000000000000000000000000000000000000000000000000000000001121 212.0
TLS3_k127_1062557_7 - - - - 0.00000000004435 72.0
TLS3_k127_1066165_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 5.388e-205 647.0
TLS3_k127_1066165_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 579.0
TLS3_k127_1066165_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 438.0
TLS3_k127_1066165_3 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 331.0
TLS3_k127_1066165_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000005244 225.0
TLS3_k127_1066165_5 pfam nudix K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000181 201.0
TLS3_k127_1066165_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000001242 172.0
TLS3_k127_1066165_7 septum formation initiator - - - 0.000000000000000007596 94.0
TLS3_k127_1066165_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000003316 67.0
TLS3_k127_1070251_0 ABC transporter (Periplasmic binding protein) K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 544.0
TLS3_k127_1070251_1 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 402.0
TLS3_k127_1070251_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 400.0
TLS3_k127_1070251_3 COG0489 ATPases involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000000000000000000000000000004605 242.0
TLS3_k127_1070251_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000002846 231.0
TLS3_k127_1070251_5 PFAM Amidase K01457 - 3.5.1.54 0.00000000000000000000000000000000000001027 163.0
TLS3_k127_107245_0 PHP domain K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 4.702e-304 947.0
TLS3_k127_107245_1 Belongs to the Nudix hydrolase family K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 391.0
TLS3_k127_107245_2 Elongation factor P - - - 0.00000000000000000000000000000000000000000000002871 172.0
TLS3_k127_107245_3 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000006009 160.0
TLS3_k127_107245_4 Domain of unknown function (DUF4399) - - - 0.000000000000000000000003942 102.0
TLS3_k127_107245_5 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.000000001436 68.0
TLS3_k127_1088950_0 ABC transporter, ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 387.0
TLS3_k127_1088950_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 370.0
TLS3_k127_1088950_2 OstA-like protein K09774 - - 0.0000000000000000000000000000000001682 136.0
TLS3_k127_1103256_0 COG3572 Gamma-glutamylcysteine synthetase K01919 - 6.3.2.2 1.982e-222 735.0
TLS3_k127_1103256_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 320.0
TLS3_k127_1103256_2 - - - - 0.000000000000000005524 91.0
TLS3_k127_1109692_0 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 584.0
TLS3_k127_1109692_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 436.0
TLS3_k127_1109692_2 protein conserved in bacteria K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 390.0
TLS3_k127_1109692_3 invasion associated locus B - - - 0.00000000000000000000000000000006543 131.0
TLS3_k127_1109692_4 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000001226 125.0
TLS3_k127_1111312_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.713e-252 784.0
TLS3_k127_1111312_1 Helicase associated domain (HA2) Add an annotation K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 354.0
TLS3_k127_1111312_2 Zinc-dependent metalloprotease K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003852 290.0
TLS3_k127_1115558_0 Alcohol dehydrogenase GroES-like domain K00121 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0008150,GO:0008152,GO:0015945,GO:0034308,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:1901615 1.1.1.1,1.1.1.284 9.785e-220 684.0
TLS3_k127_1115558_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 340.0
TLS3_k127_1115558_2 - - - - 0.00000000000000000000000000000000004596 142.0
TLS3_k127_1115558_3 - - - - 0.000000000000000115 82.0
TLS3_k127_1120979_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 7.783e-236 735.0
TLS3_k127_1120979_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 522.0
TLS3_k127_1120979_2 Cytochrome c K08738 - - 0.000000000000000000000000000002308 133.0
TLS3_k127_1120979_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000005488 89.0
TLS3_k127_1126178_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 417.0
TLS3_k127_1126178_1 ABC-type Mn2 Zn2 transport systems, permease components K11605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 406.0
TLS3_k127_1126178_2 ATPases associated with a variety of cellular activities K11607,K11710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 408.0
TLS3_k127_1126178_3 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K11604 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 398.0
TLS3_k127_1126178_4 ABC 3 transport family K02075,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 295.0
TLS3_k127_1126178_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002895 228.0
TLS3_k127_1126178_6 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000007318 188.0
TLS3_k127_1126178_7 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000004529 52.0
TLS3_k127_1126178_8 Invasion associated locus B (IalB) protein - - - 0.0009183 48.0
TLS3_k127_1129083_0 COG0165 Argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.922e-226 713.0
TLS3_k127_1129083_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 5.911e-217 681.0
TLS3_k127_1129083_2 Domain of unknown function (DUF4175) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 617.0
TLS3_k127_1129083_3 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001937 195.0
TLS3_k127_1129083_4 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000126 147.0
TLS3_k127_1129083_5 Glycosyl transferase family 8 - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 - 0.000000000000000000001656 106.0
TLS3_k127_1160582_0 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002967 265.0
TLS3_k127_1160582_1 - - - - 0.000000000000000000000000000000000003628 139.0
TLS3_k127_1160582_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000001604 131.0
TLS3_k127_1161268_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.029e-241 761.0
TLS3_k127_1161268_1 FAD dependent oxidoreductase K02846 - - 0.00000000000000000000000000000000000000000000000193 179.0
TLS3_k127_1161268_2 FR47-like protein - - - 0.0000000000000000000000000000000000002989 160.0
TLS3_k127_1161268_3 HAD-hyrolase-like - - - 0.000002722 53.0
TLS3_k127_1163088_0 Zn-dependent proteases and their inactivated homologs K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 584.0
TLS3_k127_1163088_1 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000009137 268.0
TLS3_k127_1163088_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000006541 229.0
TLS3_k127_1163088_3 transcription regulator containing HTH domain K18831 - - 0.00000000000000000000000000000000000000000000000000000002307 198.0
TLS3_k127_1163088_4 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.0000000000000000000000000000000000000000003276 161.0
TLS3_k127_1166382_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 9.827e-305 945.0
TLS3_k127_1166382_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 342.0
TLS3_k127_1166382_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 336.0
TLS3_k127_1166382_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000001112 130.0
TLS3_k127_1169062_0 2Fe-2S iron-sulfur cluster binding domain K03863 - - 0.0 1176.0
TLS3_k127_1169062_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000001949 128.0
TLS3_k127_1169062_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000001075 94.0
TLS3_k127_1170334_0 PFAM Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 398.0
TLS3_k127_1192417_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 453.0
TLS3_k127_1192417_1 - - - - 0.00000000000000000000000000000000872 130.0
TLS3_k127_1192417_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000001316 114.0
TLS3_k127_1192417_3 Protein conserved in bacteria - - - 0.0000002168 62.0
TLS3_k127_1193035_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 363.0
TLS3_k127_1193035_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 352.0
TLS3_k127_1193035_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000119 239.0
TLS3_k127_1193035_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000001254 58.0
TLS3_k127_1215443_0 GMC oxidoreductase K06151 - 1.1.99.3 4.768e-307 950.0
TLS3_k127_1215443_1 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000001785 246.0
TLS3_k127_1220113_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.388e-236 739.0
TLS3_k127_1220113_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002298 270.0
TLS3_k127_1220113_2 Domain of unknown function (DUF4394) - - - 0.00000000000000000000000000000000000000000000000000000000000002178 224.0
TLS3_k127_1220113_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000002782 168.0
TLS3_k127_1220113_4 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000000003089 82.0
TLS3_k127_1220113_5 - - - - 0.0000000000002477 76.0
TLS3_k127_1220113_6 Peptidase family S49 K04773 - - 0.0000000009315 62.0
TLS3_k127_1249075_0 Belongs to the UPF0061 (SELO) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 540.0
TLS3_k127_1249075_1 COG0505 Carbamoylphosphate synthase small subunit K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000003312 119.0
TLS3_k127_1249075_2 - - - - 0.00000000000000000003794 103.0
TLS3_k127_1249417_0 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 476.0
TLS3_k127_1249417_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 355.0
TLS3_k127_1249417_2 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 312.0
TLS3_k127_1249417_3 Peptidase family M48 K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 288.0
TLS3_k127_1249417_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000001919 177.0
TLS3_k127_1249417_5 Belongs to the HesB IscA family K13628,K15724 - - 0.00000000000000000000000000000000000000000003759 164.0
TLS3_k127_1249417_6 ThiS family - - - 0.0000000000000000000000000001732 124.0
TLS3_k127_1249417_7 Bacterial SH3 domain - - - 0.00000000000002048 81.0
TLS3_k127_1249708_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.335e-279 865.0
TLS3_k127_1249708_1 protein related to deoxyribodipyrimidine photolyase K06876 GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 6.916e-215 691.0
TLS3_k127_1249708_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 490.0
TLS3_k127_1249708_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000008754 211.0
TLS3_k127_1249708_4 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000001474 151.0
TLS3_k127_1249708_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000002294 84.0
TLS3_k127_1269052_0 DeoC/LacD family aldolase K01635 - 4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 460.0
TLS3_k127_1269052_1 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000927 247.0
TLS3_k127_1269052_2 COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain - - - 0.0000000000000000003319 89.0
TLS3_k127_1269052_3 Protein conserved in bacteria - - - 0.00000002475 65.0
TLS3_k127_129035_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K21134 - - 3.363e-213 678.0
TLS3_k127_129035_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000006899 258.0
TLS3_k127_129035_2 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000000000000000000000000000000000000000000483 237.0
TLS3_k127_129254_0 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 584.0
TLS3_k127_129254_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 540.0
TLS3_k127_129254_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 440.0
TLS3_k127_129254_3 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 359.0
TLS3_k127_129254_4 Serine dehydratase beta chain K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 289.0
TLS3_k127_129254_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
TLS3_k127_129254_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000551 242.0
TLS3_k127_129254_7 Planctomycete cytochrome C - - - 0.0000000000000000004866 91.0
TLS3_k127_129254_8 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0001508 50.0
TLS3_k127_13224_0 Glycoside hydrolase family 24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 306.0
TLS3_k127_13224_1 Phage conserved hypothetical protein BR0599 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 319.0
TLS3_k127_13224_10 Phage tail assembly chaperone protein, TAC - - - 0.00000000000008357 79.0
TLS3_k127_13224_11 - - - - 0.000009186 53.0
TLS3_k127_13224_2 GTA TIM-barrel-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 298.0
TLS3_k127_13224_3 COG5281, Phage-related minor tail protein - - - 0.000000000000000000000000000000000000000000000000000000000001333 218.0
TLS3_k127_13224_4 Major tail protein, TP901-1 family - - - 0.00000000000000000000000000000000000000000000000000000000001657 217.0
TLS3_k127_13224_5 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000000000000000000000001984 196.0
TLS3_k127_13224_6 - - - - 0.00000000000000000000000000000000000000000000000005138 187.0
TLS3_k127_13224_7 Phage head-tail joining protein - - - 0.00000000000000000000000000007429 127.0
TLS3_k127_13224_8 Phage tail tube protein, GTA-gp10 - - - 0.0000000000000000000000000007621 125.0
TLS3_k127_13224_9 Protein of unknown function (DUF3168) - - - 0.000000000000000000000006091 112.0
TLS3_k127_1353159_0 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001508 282.0
TLS3_k127_1353159_1 16S RNA G1207 methylase RsmC K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000000000000000000000000002254 237.0
TLS3_k127_1353159_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000001135 131.0
TLS3_k127_1361566_0 adenylosuccinate lyase - - - 2.933e-220 691.0
TLS3_k127_1361566_1 Glucose / Sorbosone dehydrogenase K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 418.0
TLS3_k127_1361566_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000001071 197.0
TLS3_k127_1361566_3 - - - - 0.00000000000000000000000000000000008571 137.0
TLS3_k127_1378558_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 473.0
TLS3_k127_1378558_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 440.0
TLS3_k127_1378558_10 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.00002457 57.0
TLS3_k127_1378558_2 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 403.0
TLS3_k127_1378558_3 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 378.0
TLS3_k127_1378558_4 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000002533 274.0
TLS3_k127_1378558_5 AzlC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006867 248.0
TLS3_k127_1378558_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000009679 250.0
TLS3_k127_1378558_7 Molybdopterin-guanine dinucleotide biosynthesis protein K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000008548 225.0
TLS3_k127_1378558_8 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000009024 211.0
TLS3_k127_1378558_9 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000000000000005194 135.0
TLS3_k127_1386758_0 Polysaccharide biosynthesis/export protein K01991,K16552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 397.0
TLS3_k127_1386758_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 342.0
TLS3_k127_1386758_2 Bacterial sugar transferase K00996,K16566 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000005361 270.0
TLS3_k127_1422710_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 451.0
TLS3_k127_1422710_1 bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 305.0
TLS3_k127_1422710_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000003573 136.0
TLS3_k127_1422710_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000001062 127.0
TLS3_k127_1445408_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 567.0
TLS3_k127_1445408_1 Two component transcriptional regulator, winged helix family K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 440.0
TLS3_k127_1445408_2 PFAM N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 310.0
TLS3_k127_1445408_3 Protein conserved in bacteria K09948 - - 0.000000000000000000000000000000000000000005437 156.0
TLS3_k127_1445408_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000001685 139.0
TLS3_k127_1445408_5 Protein of unknown function (DUF1153) - - - 0.00000000000000000000003593 115.0
TLS3_k127_1470601_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000003869 228.0
TLS3_k127_1470601_1 PFAM sulfotransferase - - - 0.0000000000000000000000000000000000000000000000000000003407 209.0
TLS3_k127_1470601_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000001107 196.0
TLS3_k127_1470601_3 - - - - 0.00000000000000000001041 102.0
TLS3_k127_1480203_0 TIGRFAM phage tail protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 379.0
TLS3_k127_1480203_1 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 335.0
TLS3_k127_1480203_2 homolog of phage Mu protein gp47 - - - 0.0000000000000000000000000000000000000000000000000000000000007291 218.0
TLS3_k127_1480203_3 - - - - 0.0000000000000000000000000007265 132.0
TLS3_k127_1480203_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000709 68.0
TLS3_k127_1487198_0 acyl-CoA dehydrogenase K00252 - 1.3.8.6 2.567e-219 685.0
TLS3_k127_1487198_1 Beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 405.0
TLS3_k127_1487198_2 Pfam matches to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1 K07126 - - 0.00000000000000000000000009188 118.0
TLS3_k127_1487198_3 Sel1-like repeats. K07126 - - 0.00000000000000000000008102 105.0
TLS3_k127_1487198_4 Sel1-like repeats. K07126 - - 0.00000000000000003751 89.0
TLS3_k127_149953_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 4.034e-238 751.0
TLS3_k127_149953_1 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
TLS3_k127_149953_2 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000006993 229.0
TLS3_k127_149953_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000002099 201.0
TLS3_k127_149953_4 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000006957 170.0
TLS3_k127_149953_5 gag-polyprotein putative aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000001671 166.0
TLS3_k127_149953_6 UPF0056 membrane protein K05595 - - 0.0000000000000002415 89.0
TLS3_k127_1517710_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.821e-313 972.0
TLS3_k127_1517710_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 592.0
TLS3_k127_1517710_2 Belongs to the phosphoglycerate kinase family K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 565.0
TLS3_k127_1517710_3 Aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 513.0
TLS3_k127_1517710_4 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000001647 120.0
TLS3_k127_1526071_0 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 484.0
TLS3_k127_1526071_1 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 420.0
TLS3_k127_1526071_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
TLS3_k127_1526071_3 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000002372 170.0
TLS3_k127_1526071_4 - - - - 0.0000000000000000000000000000000002507 152.0
TLS3_k127_1526071_5 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000003781 133.0
TLS3_k127_1526071_6 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000006098 124.0
TLS3_k127_1535892_0 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 466.0
TLS3_k127_1535892_1 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 388.0
TLS3_k127_1535892_2 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 284.0
TLS3_k127_1535892_3 ATPase (AAA K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000248 277.0
TLS3_k127_1535892_4 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001789 222.0
TLS3_k127_1535892_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000001239 179.0
TLS3_k127_1547634_0 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 411.0
TLS3_k127_1547634_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 393.0
TLS3_k127_1547634_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 390.0
TLS3_k127_1547634_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 352.0
TLS3_k127_1547634_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 306.0
TLS3_k127_1547634_5 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003189 276.0
TLS3_k127_1547634_6 PFAM phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000175 123.0
TLS3_k127_1550888_0 COG0534 Na -driven multidrug efflux pump K03327 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 529.0
TLS3_k127_1550888_1 Na phosphate symporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 526.0
TLS3_k127_1550888_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 462.0
TLS3_k127_1550888_3 Cupin - - - 0.000000000000000000000000000000000000000000000000000000006157 202.0
TLS3_k127_1550888_4 Protein of unknown function (DUF952) - - - 0.000000000000000000000000000000000000054 144.0
TLS3_k127_156654_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 329.0
TLS3_k127_156654_1 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000001229 185.0
TLS3_k127_1589709_0 Cytochrome c-type biogenesis protein K02198 - - 2.936e-295 928.0
TLS3_k127_1589709_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 499.0
TLS3_k127_1589709_2 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 359.0
TLS3_k127_1589709_3 Predicted Peptidoglycan domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 288.0
TLS3_k127_1589709_4 Holin of 3TMs, for gene-transfer release - - - 0.00000000000000000000000000000000000002504 160.0
TLS3_k127_1589709_5 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000003213 157.0
TLS3_k127_1594438_0 PFAM Glutamine synthetase, catalytic K01915 - 6.3.1.2 2.061e-196 623.0
TLS3_k127_1594438_1 Subtilase family - - - 0.000000000433 63.0
TLS3_k127_1595379_0 Protein conserved in bacteria K16514 - 5.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 590.0
TLS3_k127_1595379_1 Isocitrate/isopropylmalate dehydrogenase K00031,K00052,K07246 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.42,1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 308.0
TLS3_k127_1595379_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000000000000000000002269 124.0
TLS3_k127_1596969_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.79e-248 774.0
TLS3_k127_1596969_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 602.0
TLS3_k127_1596969_10 Acetyltransferase (GNAT) family - - - 0.0000000000000000001624 93.0
TLS3_k127_1596969_2 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 571.0
TLS3_k127_1596969_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 376.0
TLS3_k127_1596969_4 EamA-like transporter family K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 354.0
TLS3_k127_1596969_5 COG1349 Transcriptional regulators of sugar metabolism K02444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 333.0
TLS3_k127_1596969_6 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
TLS3_k127_1596969_7 NAD-dependent epimerase dehydratase K18981 - 1.1.1.203 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 310.0
TLS3_k127_1596969_8 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004701 232.0
TLS3_k127_1596969_9 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000005557 211.0
TLS3_k127_1609807_0 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 453.0
TLS3_k127_1609807_1 short-chain dehydrogenase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 334.0
TLS3_k127_1609807_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000004103 209.0
TLS3_k127_1609807_3 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.00000000000000000000000000000000000000000000000006588 186.0
TLS3_k127_1609807_4 protein conserved in bacteria K05805 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000006421 158.0
TLS3_k127_1609807_5 acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000007964 101.0
TLS3_k127_1648794_0 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 543.0
TLS3_k127_1648794_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000002503 245.0
TLS3_k127_1651060_0 COG3552 Protein containing von Willebrand factor type A (vWA) domain K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 579.0
TLS3_k127_1651060_1 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 485.0
TLS3_k127_1651060_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 444.0
TLS3_k127_1651060_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002844 246.0
TLS3_k127_1651060_4 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000000000000000005508 190.0
TLS3_k127_1651060_5 Domain of unknown function (DUF4260) - - - 0.00000000000000000000000000009967 119.0
TLS3_k127_1653009_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.991e-229 719.0
TLS3_k127_1653009_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 328.0
TLS3_k127_1653009_2 COG0616 periplasmic serine proteases (ClpP class) K04773,K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 316.0
TLS3_k127_1663490_0 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007233 270.0
TLS3_k127_1663490_1 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001796 199.0
TLS3_k127_1663490_2 Beta-Ig-H3 fasciclin - - - 0.000000000000000000000000000000000000009833 160.0
TLS3_k127_1663490_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000007596 136.0
TLS3_k127_1663490_4 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000001709 113.0
TLS3_k127_1663490_5 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000041 78.0
TLS3_k127_1664839_0 DEAD DEAH box helicase K03724 - - 0.0 1118.0
TLS3_k127_1664839_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.615e-282 872.0
TLS3_k127_1664839_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 414.0
TLS3_k127_1664839_3 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 353.0
TLS3_k127_1664839_4 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001894 274.0
TLS3_k127_1664839_5 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004028 250.0
TLS3_k127_1664839_6 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000001211 205.0
TLS3_k127_1664839_7 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000001296 189.0
TLS3_k127_1664839_8 PFAM Chorismate mutase K04782 - 4.2.99.21 0.0000000000000000000000000004646 115.0
TLS3_k127_1664839_9 protein conserved in bacteria K09796 - - 0.00000000000002041 79.0
TLS3_k127_1668785_0 Thi4 family K00311 - 1.5.5.1 3.459e-286 893.0
TLS3_k127_1668785_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 469.0
TLS3_k127_1668785_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009322 241.0
TLS3_k127_1668785_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000001931 191.0
TLS3_k127_1668785_4 - - - - 0.000000000000000002172 97.0
TLS3_k127_1686430_0 glycosyl transferase group 1 K16703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 303.0
TLS3_k127_1686430_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005362 286.0
TLS3_k127_1686430_2 SOS response K14160 - - 0.00000000000000000000000000000003703 132.0
TLS3_k127_1691875_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 537.0
TLS3_k127_1691875_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 297.0
TLS3_k127_1691875_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000003442 169.0
TLS3_k127_1691875_3 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000006047 102.0
TLS3_k127_1691875_4 Outer membrane protein beta-barrel domain - - - 0.0000000000005758 77.0
TLS3_k127_1691875_5 Protein conserved in bacteria - - - 0.0007884 49.0
TLS3_k127_1694825_0 Mg2 and Co2 transporter CorB K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 554.0
TLS3_k127_1694825_1 Tyrosine recombinase K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 382.0
TLS3_k127_1694825_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000004655 217.0
TLS3_k127_1694825_3 - - - - 0.0000002179 58.0
TLS3_k127_1723146_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 454.0
TLS3_k127_1723146_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000004574 161.0
TLS3_k127_1731821_0 CoA binding domain K09181 - - 1.41e-276 879.0
TLS3_k127_1731821_1 Peptidase family M50 - - - 0.00008328 46.0
TLS3_k127_1744374_0 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 338.0
TLS3_k127_1744374_1 Transcriptional regulator GntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004782 248.0
TLS3_k127_1744374_2 Amb_all - - - 0.00000000000000000000000000000000000000001194 176.0
TLS3_k127_1744374_3 Parallel beta-helix repeats - - - 0.00002462 56.0
TLS3_k127_1766109_0 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000003663 130.0
TLS3_k127_1766109_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000002762 123.0
TLS3_k127_1780336_0 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 327.0
TLS3_k127_1780336_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001548 263.0
TLS3_k127_1780336_2 COG1684 Flagellar biosynthesis pathway, component FliR K02421 - - 0.000000000000000000000000000000000000000000000000009973 186.0
TLS3_k127_1780336_3 SBF-like CPA transporter family (DUF4137) K03453 - - 0.00000000000000000000000000000000000000000000001308 183.0
TLS3_k127_1780336_4 Controls the rotational direction of flagella during chemotaxis - - - 0.000000000000000000000000000000002216 134.0
TLS3_k127_1780336_5 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000000000000000004358 132.0
TLS3_k127_1780336_6 COG1684 Flagellar biosynthesis pathway, component FliR K02421 - - 0.000000004149 59.0
TLS3_k127_1791124_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.37e-222 702.0
TLS3_k127_1791124_1 auxin efflux carrier family protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 331.0
TLS3_k127_1791124_2 Hemimethylated DNA-binding protein YccV like K11940 - - 0.000000000000000000000000000000000000000000000002878 178.0
TLS3_k127_1791124_3 FR47-like protein - - - 0.00000000000000000000000000000000000000000000593 171.0
TLS3_k127_1791124_4 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000000000000000003323 156.0
TLS3_k127_1796219_0 ABC-type tungstate transport system, periplasmic component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 329.0
TLS3_k127_1796219_1 COG1910, Periplasmic molybdate-binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 334.0
TLS3_k127_1796219_2 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 303.0
TLS3_k127_1796219_3 ABC-type polar amino acid transport system ATPase component K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 289.0
TLS3_k127_1799889_0 Flavin containing amine oxidoreductase K00466 - 1.13.12.3 8.844e-294 921.0
TLS3_k127_1799889_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000446 271.0
TLS3_k127_1799889_2 Hydroxyethylthiazole kinase family K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000008037 164.0
TLS3_k127_1799889_3 Protein of unknown function (DUF2852) - - - 0.000000000000000000000000000000000000008339 149.0
TLS3_k127_1802127_0 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 383.0
TLS3_k127_1802127_1 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 342.0
TLS3_k127_1802127_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000266 203.0
TLS3_k127_1802127_3 - - - - 0.0000000000000002545 83.0
TLS3_k127_1802127_4 Heavy-metal resistance - - - 0.00000000007618 68.0
TLS3_k127_1802127_5 Ca2 -binding protein (EF-Hand superfamily - - - 0.000000536 60.0
TLS3_k127_1806477_0 Fructose-1,6-bisphosphatase K02446,K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 508.0
TLS3_k127_1806477_1 DHHA1 domain K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 261.0
TLS3_k127_1814575_0 Glucose dehydrogenase C-terminus K05351 - 1.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 539.0
TLS3_k127_1814575_1 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001636 294.0
TLS3_k127_1814575_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000001237 91.0
TLS3_k127_1818304_0 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 398.0
TLS3_k127_1818304_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 336.0
TLS3_k127_1818304_2 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001961 238.0
TLS3_k127_1818304_3 YCII-related domain K09780 - - 0.0000006857 53.0
TLS3_k127_1827064_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 366.0
TLS3_k127_1827064_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 332.0
TLS3_k127_1827064_2 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 306.0
TLS3_k127_1827064_3 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.000000000000000000000000004346 115.0
TLS3_k127_1827064_4 TIGRFAM methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000005707 102.0
TLS3_k127_1828187_0 Belongs to the binding-protein-dependent transport system permease family K10553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 564.0
TLS3_k127_1828187_1 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 559.0
TLS3_k127_1828187_10 Phosphoribulokinase / Uridine kinase family - - - 0.00000000000000000000000000000000000000000000000000000000000178 227.0
TLS3_k127_1828187_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000003911 202.0
TLS3_k127_1828187_12 polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000005659 177.0
TLS3_k127_1828187_13 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000001253 166.0
TLS3_k127_1828187_14 Protein of unknown function (DUF2934) - - - 0.00000003242 60.0
TLS3_k127_1828187_2 ABC-type sugar transport system, periplasmic component K10552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 533.0
TLS3_k127_1828187_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 500.0
TLS3_k127_1828187_4 PFAM FAD dependent oxidoreductase K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 492.0
TLS3_k127_1828187_5 ABC transporter K10554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 449.0
TLS3_k127_1828187_6 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 423.0
TLS3_k127_1828187_7 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 409.0
TLS3_k127_1828187_8 KR domain K00046 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008874,GO:0008875,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0042802,GO:0042803,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 384.0
TLS3_k127_1828187_9 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 368.0
TLS3_k127_1874052_0 Amidohydrolase family K01485 - 3.5.4.1 2.138e-212 669.0
TLS3_k127_1874052_1 acyl-CoA transferases carnitine dehydratase K14470 - 5.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 576.0
TLS3_k127_1874052_2 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 485.0
TLS3_k127_1874052_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 461.0
TLS3_k127_1874052_4 PFAM ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 337.0
TLS3_k127_1874052_5 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000000000000000001459 214.0
TLS3_k127_1875780_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 514.0
TLS3_k127_1875780_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 387.0
TLS3_k127_1895808_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 2.593e-320 1000.0
TLS3_k127_1895808_1 EamA-like transporter family - - - 0.00000000000000000000000002946 109.0
TLS3_k127_1917867_0 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 1.183e-232 725.0
TLS3_k127_1917867_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 348.0
TLS3_k127_1917867_2 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001754 227.0
TLS3_k127_1917867_3 Endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000001373 230.0
TLS3_k127_1917867_4 Xylulose kinase K00854 GO:0003674,GO:0003824,GO:0004856,GO:0005975,GO:0005996,GO:0005997,GO:0005998,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.17 0.000000000000000000000000000000000000001917 151.0
TLS3_k127_1919343_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 456.0
TLS3_k127_1950094_0 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 334.0
TLS3_k127_1950094_1 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 318.0
TLS3_k127_1950094_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000001296 221.0
TLS3_k127_1950094_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000001882 209.0
TLS3_k127_1950094_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000001578 199.0
TLS3_k127_1950094_5 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000042 141.0
TLS3_k127_1950094_6 Belongs to the bacterial ribosomal protein bL31 family K02909 - - 0.00000000000000000000000000000001294 136.0
TLS3_k127_1956723_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 2.461e-293 920.0
TLS3_k127_1956723_1 Oxidative deamination of D-amino acids K00285 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0008718,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019478,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055114,GO:0055130,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 546.0
TLS3_k127_1956723_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 392.0
TLS3_k127_1956723_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000008238 165.0
TLS3_k127_1956723_4 Sarcosine oxidase, gamma subunit K00305 - 1.5.3.1 0.00000000000003287 81.0
TLS3_k127_1956723_5 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000076 77.0
TLS3_k127_198177_0 YmdB-like protein K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 409.0
TLS3_k127_198177_1 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000003848 254.0
TLS3_k127_198177_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000002884 188.0
TLS3_k127_198177_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000002071 109.0
TLS3_k127_1992039_0 ABC transporter transmembrane region K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 1.809e-266 833.0
TLS3_k127_1992039_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 581.0
TLS3_k127_1992039_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 426.0
TLS3_k127_1992039_3 protein containing LysM domain - - - 0.00000000000000000000000000000000000000009253 158.0
TLS3_k127_1996641_0 IG-like fold at C-terminal of FixG, putative oxidoreductase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 9.343e-211 666.0
TLS3_k127_1996641_1 transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 304.0
TLS3_k127_1996641_2 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000176 295.0
TLS3_k127_1996641_3 PFAM FixH family protein - - - 0.0000000000000000000000000000003408 136.0
TLS3_k127_1996641_4 transcriptional regulators - - - 0.0000000000000000000000000003375 117.0
TLS3_k127_1996641_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000001163 94.0
TLS3_k127_200838_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 510.0
TLS3_k127_200838_1 Glutathione S-transferase K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 474.0
TLS3_k127_200838_10 Acetyltransferase (GNAT) domain K03824 - - 0.00000000000000000000000000000000131 141.0
TLS3_k127_200838_11 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000008356 127.0
TLS3_k127_200838_12 - - - - 0.00000004345 61.0
TLS3_k127_200838_2 PFAM Mandelate racemase muconate lactonizing K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 410.0
TLS3_k127_200838_3 Amino-transferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 391.0
TLS3_k127_200838_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 370.0
TLS3_k127_200838_5 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 303.0
TLS3_k127_200838_6 Belongs to the GcvT family K06980,K22073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009022 271.0
TLS3_k127_200838_7 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000119 251.0
TLS3_k127_200838_8 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006464 205.0
TLS3_k127_200838_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000002464 165.0
TLS3_k127_2008711_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 3.096e-245 771.0
TLS3_k127_2008711_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 338.0
TLS3_k127_2008711_2 MOSC domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001652 292.0
TLS3_k127_2008711_3 acetyltransferase, isoleucine patch superfamily K00638,K18234 - 2.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002024 286.0
TLS3_k127_2008711_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
TLS3_k127_2009441_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 504.0
TLS3_k127_2009441_1 Flagellar protein FlgJ - - - 0.00000000000001265 78.0
TLS3_k127_2009441_2 Domain of unknown function (DUF1127) - - - 0.0000000002574 64.0
TLS3_k127_2020490_0 FAD linked oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 610.0
TLS3_k127_2020490_1 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 420.0
TLS3_k127_2020490_2 cytosine deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 368.0
TLS3_k127_2020490_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000565 207.0
TLS3_k127_2020490_4 Nitrate sulfonate bicarbonate K02051 - - 0.0000000000000000000000000000000000000000001014 162.0
TLS3_k127_2046839_0 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 313.0
TLS3_k127_2046839_1 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 313.0
TLS3_k127_2046839_2 - - - - 0.000000000000005311 84.0
TLS3_k127_2046839_3 Acts as a magnesium transporter K06213 - - 0.0000002235 59.0
TLS3_k127_2083986_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 476.0
TLS3_k127_2083986_1 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 373.0
TLS3_k127_2083986_2 Aldo keto reductase K00064 - 1.1.1.122 0.00000000000000000000000000000000000000176 151.0
TLS3_k127_2101008_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 2.69e-263 847.0
TLS3_k127_2101008_1 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 3.801e-216 682.0
TLS3_k127_2101008_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 428.0
TLS3_k127_2101008_3 COG2113 ABC-type proline glycine betaine transport systems, periplasmic components K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 412.0
TLS3_k127_2101008_4 Binding-protein-dependent transport system inner membrane component K02001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 393.0
TLS3_k127_2101008_5 ATPases associated with a variety of cellular activities K02000 GO:0000166,GO:0003674,GO:0004888,GO:0005034,GO:0005215,GO:0005275,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015837,GO:0015838,GO:0016020,GO:0016021,GO:0017076,GO:0022857,GO:0023052,GO:0030554,GO:0031224,GO:0031460,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0038023,GO:0043167,GO:0043168,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060089,GO:0065007,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 378.0
TLS3_k127_2101008_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 294.0
TLS3_k127_2101008_7 BetI-type transcriptional repressor, C-terminal K02167 - - 0.0000000000000000000000000000000000000000000000000007544 190.0
TLS3_k127_2101008_8 CHRD domain - - - 0.000000000000000000004171 107.0
TLS3_k127_2101008_9 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000229 103.0
TLS3_k127_2107144_0 Cytochrome C and Quinol oxidase polypeptide I K02274,K15408 - 1.9.3.1 0.0 1140.0
TLS3_k127_2107144_1 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000006965 263.0
TLS3_k127_2134786_0 component I K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 425.0
TLS3_k127_2134786_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 409.0
TLS3_k127_2134786_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 300.0
TLS3_k127_2134786_3 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000007469 250.0
TLS3_k127_2134786_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000008453 264.0
TLS3_k127_2134786_5 Amino-transferase class IV K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000000000000002577 206.0
TLS3_k127_2134786_6 Abortive infection protein - - - 0.000000000000000000000000000000000000000000000000002776 192.0
TLS3_k127_2138669_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 7.601e-319 1002.0
TLS3_k127_2138669_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 9.032e-204 641.0
TLS3_k127_2138669_2 Aldehyde dehydrogenase K00132,K15515 - 1.2.1.10,1.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 467.0
TLS3_k127_2138669_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 352.0
TLS3_k127_2138669_4 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
TLS3_k127_2138669_5 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 255.0
TLS3_k127_2138669_6 DeoR C terminal sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009328 239.0
TLS3_k127_2138669_7 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.000000000000000000000000000000000002294 139.0
TLS3_k127_2138669_8 Ethanolamine utilization protein EutN K04028 - - 0.000000000000000000000002794 111.0
TLS3_k127_2138669_9 - - - - 0.0001166 53.0
TLS3_k127_2146827_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 559.0
TLS3_k127_2146827_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 559.0
TLS3_k127_2155167_0 carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 456.0
TLS3_k127_2160660_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 3.612e-240 763.0
TLS3_k127_2160660_1 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.0000000000000000000000000000000000000000000000000000000000000000000000000001678 265.0
TLS3_k127_2160660_2 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002658 278.0
TLS3_k127_2160660_3 Protein of unknown function (DUF2927) - - - 0.000000000000000000000000000000000000000000000000000000000000000002627 237.0
TLS3_k127_2160660_4 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000004269 229.0
TLS3_k127_2160660_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000006636 189.0
TLS3_k127_2160660_6 - - - - 0.00000508 54.0
TLS3_k127_2191011_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 523.0
TLS3_k127_2191011_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 427.0
TLS3_k127_2191011_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 409.0
TLS3_k127_2191011_3 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 385.0
TLS3_k127_2191011_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 349.0
TLS3_k127_2191011_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000002063 229.0
TLS3_k127_2191011_6 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000008174 227.0
TLS3_k127_2191011_7 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000006024 189.0
TLS3_k127_2191011_8 PRC-barrel domain - - - 0.0000000000000000000000000000000002606 149.0
TLS3_k127_2210019_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 1.074e-307 966.0
TLS3_k127_2210019_1 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 329.0
TLS3_k127_2210019_2 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
TLS3_k127_2210019_3 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 270.0
TLS3_k127_2210019_4 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000058 285.0
TLS3_k127_2210019_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000002215 217.0
TLS3_k127_2210019_6 Sarcosine oxidase, gamma subunit K00305 - 1.5.3.1 0.000000000000000000000000000000000002608 144.0
TLS3_k127_2210923_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 473.0
TLS3_k127_2210923_1 Phytoene squalene synthetase K02291,K18163 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000005379 220.0
TLS3_k127_2210923_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000002767 203.0
TLS3_k127_2210923_3 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000001273 83.0
TLS3_k127_2226171_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.195e-212 670.0
TLS3_k127_2226171_1 PQQ-like domain K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 373.0
TLS3_k127_2226171_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 320.0
TLS3_k127_2226171_3 Intracellular protease K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000008007 252.0
TLS3_k127_2226171_4 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.0000002499 53.0
TLS3_k127_2226171_5 epoxide hydrolase K21159 - - 0.00002177 48.0
TLS3_k127_2226171_6 epoxide hydrolase K01253 - 3.3.2.9 0.0004205 51.0
TLS3_k127_2229145_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 482.0
TLS3_k127_2229145_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000242 216.0
TLS3_k127_2229145_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000003521 219.0
TLS3_k127_2229145_3 L-alanine exporter - - - 0.0000000000000000000000000000000000000000000000000002912 189.0
TLS3_k127_2229145_4 Protein of unknown function (DUF1491) - - - 0.000000000000000000000000000000000000000000006764 179.0
TLS3_k127_2237328_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 460.0
TLS3_k127_2237328_1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 310.0
TLS3_k127_2237328_2 COG1587 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000001902 126.0
TLS3_k127_2237328_3 Membrane - - - 0.00000000000000000004311 104.0
TLS3_k127_2261531_0 forms a complex with serine acetyltransferase CysE K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 543.0
TLS3_k127_2261531_1 mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 499.0
TLS3_k127_2261531_2 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000004026 211.0
TLS3_k127_2261531_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000006179 161.0
TLS3_k127_2261531_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000004248 148.0
TLS3_k127_2263693_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.572e-233 728.0
TLS3_k127_2263693_1 PFAM Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 427.0
TLS3_k127_2263693_2 Belongs to the MT-A70-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 365.0
TLS3_k127_2263693_3 Restriction endonuclease BglII - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 302.0
TLS3_k127_2263693_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002897 272.0
TLS3_k127_2263693_5 - - - - 0.0000000003378 70.0
TLS3_k127_2270122_0 Penicillin-binding protein 5, C-terminal domain K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 315.0
TLS3_k127_2270122_1 - - - - 0.000004938 54.0
TLS3_k127_2275967_0 Allophanate hydrolase subunit 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 472.0
TLS3_k127_2275967_1 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 430.0
TLS3_k127_2275967_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 315.0
TLS3_k127_2275967_3 Allophanate hydrolase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001724 256.0
TLS3_k127_2275967_4 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000001108 206.0
TLS3_k127_2275967_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000001219 186.0
TLS3_k127_2275967_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000008776 156.0
TLS3_k127_2275967_7 - - - - 0.0000000000000000357 82.0
TLS3_k127_2300307_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 4.848e-317 977.0
TLS3_k127_2300307_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 595.0
TLS3_k127_2300307_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 582.0
TLS3_k127_2300307_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 484.0
TLS3_k127_2300307_4 CAAX amino terminal protease family protein K07052 - - 0.0000000000000000000000000000000000000000003592 170.0
TLS3_k127_2300307_5 Acetyltransferase (GNAT) domain K03827 - - 0.0000000000000000000000000000000006096 136.0
TLS3_k127_2300307_6 - - - - 0.0000000005313 69.0
TLS3_k127_2312736_0 Type II/IV secretion system protein K02283,K20527 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 632.0
TLS3_k127_2312736_1 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 366.0
TLS3_k127_2312736_10 Flp Fap pilin component K02651 - - 0.000000005697 61.0
TLS3_k127_2312736_2 Pilus assembly protein K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002902 280.0
TLS3_k127_2312736_3 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000000000000000000000000000000000000000001138 214.0
TLS3_k127_2312736_4 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000384 216.0
TLS3_k127_2312736_5 soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000197 195.0
TLS3_k127_2312736_6 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000113 177.0
TLS3_k127_2312736_7 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000002552 181.0
TLS3_k127_2312736_8 PFAM TadE family protein - - - 0.0000000000006282 77.0
TLS3_k127_2312736_9 - - - - 0.000000005224 65.0
TLS3_k127_2333606_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 534.0
TLS3_k127_2333606_1 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000004173 199.0
TLS3_k127_2333606_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000005496 121.0
TLS3_k127_2333606_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000007615 115.0
TLS3_k127_2339493_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 9.761e-225 706.0
TLS3_k127_2339493_1 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000001595 210.0
TLS3_k127_2339493_2 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000001097 180.0
TLS3_k127_2355115_0 Two component, sigma54 specific transcriptional regulator, fis family K10912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 526.0
TLS3_k127_2355115_1 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 316.0
TLS3_k127_2355115_2 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000001497 77.0
TLS3_k127_2363357_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000231 239.0
TLS3_k127_2363357_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000005159 183.0
TLS3_k127_2363357_3 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000007501 167.0
TLS3_k127_237566_0 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 596.0
TLS3_k127_237566_1 Polyamine ABC transporter, permease K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 499.0
TLS3_k127_237566_2 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 501.0
TLS3_k127_237566_3 Animal haem peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 351.0
TLS3_k127_237566_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002864 280.0
TLS3_k127_237566_5 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000282 251.0
TLS3_k127_237566_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000003851 154.0
TLS3_k127_237566_7 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000009078 161.0
TLS3_k127_237566_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000006548 147.0
TLS3_k127_237566_9 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000004062 107.0
TLS3_k127_2379632_0 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 362.0
TLS3_k127_2379632_1 Dioxygenase K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000001951 229.0
TLS3_k127_2379632_2 Alpha/beta hydrolase family K01055,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000000000000000001799 208.0
TLS3_k127_2379632_3 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000002479 187.0
TLS3_k127_2394563_0 ABC-type transport system involved in Fe-S cluster assembly, permease component K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 6.97e-300 929.0
TLS3_k127_2394563_1 ABC-type transport system involved in Fe-S cluster assembly, permease component K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 565.0
TLS3_k127_2394563_2 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 481.0
TLS3_k127_2394563_3 FeS assembly ATPase SufC K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 431.0
TLS3_k127_2394563_4 Aminotransferase class-V K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 407.0
TLS3_k127_2394563_5 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 379.0
TLS3_k127_2394563_6 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000000000000000000000000000000000111 235.0
TLS3_k127_2394563_7 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
TLS3_k127_2394563_8 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.000000000000000000000000000000000000000000000000000000000000001238 223.0
TLS3_k127_2394563_9 - - - - 0.000000000000000006451 93.0
TLS3_k127_2394711_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 578.0
TLS3_k127_2394711_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 490.0
TLS3_k127_2394711_2 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 451.0
TLS3_k127_2394711_3 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 318.0
TLS3_k127_2394711_4 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000008905 216.0
TLS3_k127_2394711_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000006619 112.0
TLS3_k127_2396246_0 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.841e-220 695.0
TLS3_k127_2450763_0 Alpha-2-Macroglobulin K06894 - - 1.485e-286 918.0
TLS3_k127_2450763_1 Protein of unknown function (DUF1013) K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 345.0
TLS3_k127_2450763_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00076 - 1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000005951 249.0
TLS3_k127_2450763_3 Belongs to the RNase T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.0000000000000000000000000000000000000000000000000000000001934 212.0
TLS3_k127_2450763_4 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000003043 145.0
TLS3_k127_2450763_5 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000001172 108.0
TLS3_k127_2450763_6 transcriptional regulator - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009268,GO:0009438,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010447,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046185,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051596,GO:0051716,GO:0060255,GO:0061727,GO:0065007,GO:0071214,GO:0071467,GO:0071468,GO:0071704,GO:0072330,GO:0080090,GO:0104004,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000341 55.0
TLS3_k127_2476663_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 462.0
TLS3_k127_2476663_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000005208 203.0
TLS3_k127_2476663_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000003259 140.0
TLS3_k127_2492174_0 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 419.0
TLS3_k127_2492174_1 PFAM Electron transfer flavoprotein alpha beta-subunit K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 420.0
TLS3_k127_2518193_0 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009225 252.0
TLS3_k127_2518193_1 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.00000001299 65.0
TLS3_k127_2540479_0 Short-chain dehydrogenase reductase sdr K22185,K22215 - 1.1.1.120,1.1.1.175,1.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 335.0
TLS3_k127_2540479_1 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000006207 233.0
TLS3_k127_2540479_2 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000002018 183.0
TLS3_k127_2573444_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 398.0
TLS3_k127_2573444_1 Oligosaccharide biosynthesis protein Alg14 like - - - 0.0000000000000000000000000000000000000005009 156.0
TLS3_k127_2573444_2 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000001776 147.0
TLS3_k127_2585190_0 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 522.0
TLS3_k127_2585190_1 Histidine kinase K07679 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 362.0
TLS3_k127_2585190_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000006665 183.0
TLS3_k127_2630515_0 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 412.0
TLS3_k127_2630515_1 ABC-type sugar transport system, periplasmic component K10552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 306.0
TLS3_k127_2630515_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 298.0
TLS3_k127_2630515_3 MAPEG family - - - 0.000000000000000000001657 100.0
TLS3_k127_2638666_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 572.0
TLS3_k127_2638666_1 Acetamidase/Formamidase family K01455 - 3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 533.0
TLS3_k127_2638666_2 Branched-chain amino acid transport system / permease component K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 512.0
TLS3_k127_2638666_3 Aldo keto reductase - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 452.0
TLS3_k127_2638666_4 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995,K11957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 445.0
TLS3_k127_2638666_5 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 400.0
TLS3_k127_2638666_6 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 370.0
TLS3_k127_2638666_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 342.0
TLS3_k127_2652272_0 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 582.0
TLS3_k127_2652272_1 Major Facilitator K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 336.0
TLS3_k127_2652272_2 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000001365 250.0
TLS3_k127_2652272_3 Glycosyltransferase like family 2 - - - 0.00000000006606 64.0
TLS3_k127_2678274_0 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 346.0
TLS3_k127_2678274_1 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 297.0
TLS3_k127_2678274_2 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006187 285.0
TLS3_k127_2678274_3 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003057 244.0
TLS3_k127_2678274_4 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000008131 195.0
TLS3_k127_2678274_5 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000001299 151.0
TLS3_k127_2678274_6 FCD - - - 0.00000000000000000000000000003464 127.0
TLS3_k127_2678274_7 GlcNAc-PI de-N-acetylase - - - 0.0000000000000004296 88.0
TLS3_k127_268472_0 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 581.0
TLS3_k127_268472_1 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 243.0
TLS3_k127_268472_2 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02388 - - 0.0000000000000000000000000000000000000000003155 163.0
TLS3_k127_268472_3 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000003264 107.0
TLS3_k127_268472_4 Bacterial export proteins, family 3 K02420 - - 0.0000000000000000000000007377 106.0
TLS3_k127_268472_5 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000001139 85.0
TLS3_k127_268472_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000001886 55.0
TLS3_k127_2711735_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 396.0
TLS3_k127_2711735_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
TLS3_k127_2711735_2 Transcriptional Regulator, AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000521 213.0
TLS3_k127_2711735_3 threonine efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000003324 214.0
TLS3_k127_2714517_0 amino acid aldolase or racemase K18425 - 4.1.3.41 4.189e-215 690.0
TLS3_k127_2714517_1 PFAM aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 573.0
TLS3_k127_2714517_2 COG1171 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 567.0
TLS3_k127_2714517_3 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 493.0
TLS3_k127_2714517_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 340.0
TLS3_k127_2714517_5 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 318.0
TLS3_k127_2714517_6 transcriptional regulator K13641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 290.0
TLS3_k127_2714517_7 Molybdenum cofactor biosynthesis protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006219 254.0
TLS3_k127_2714517_8 LysE type translocator K06895 - - 0.0000000000000000000000001862 116.0
TLS3_k127_2714517_9 Cupin domain - - - 0.0000000000000000000001054 99.0
TLS3_k127_2721866_0 epimerase dehydratase K01784,K08678,K12454,K17947 - 4.1.1.35,5.1.3.10,5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 350.0
TLS3_k127_2721866_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 246.0
TLS3_k127_2721866_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.00000000000000000000000000000000000000000000000000000000000000000001893 241.0
TLS3_k127_2721866_3 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000001112 238.0
TLS3_k127_2721866_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000003247 233.0
TLS3_k127_2721866_5 Protein involved in cysteine biosynthesis K06203 - - 0.00000000000000000000000000000000000000000000000000000000000000001218 241.0
TLS3_k127_2721866_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000009973 224.0
TLS3_k127_2721866_7 Crp-like helix-turn-helix domain - - - 0.0000000000000000001517 98.0
TLS3_k127_2730472_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 488.0
TLS3_k127_2730472_1 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 342.0
TLS3_k127_2730472_2 Heme peroxidase family protein,putative calcium-binding protein K19511 - 1.11.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005361 299.0
TLS3_k127_2730472_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000001805 207.0
TLS3_k127_2730472_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000001114 205.0
TLS3_k127_2730472_5 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000002596 176.0
TLS3_k127_2730472_6 nuclease - - - 0.00000000000000000000000000000001836 133.0
TLS3_k127_2738911_0 Protein of unknown function (DUF3604) - - - 4.295e-303 942.0
TLS3_k127_2738911_1 Hydrogenase urease accessory protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000004774 228.0
TLS3_k127_2738911_2 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000001251 146.0
TLS3_k127_2738911_3 - - - - 0.000001109 63.0
TLS3_k127_2773787_0 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP K11333 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 557.0
TLS3_k127_2773787_1 Chlorophyllide reductase subunit Y K11334 - 1.3.7.14,1.3.7.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 464.0
TLS3_k127_2773787_2 COG1233 Phytoene dehydrogenase and related proteins K09845 - 1.3.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 456.0
TLS3_k127_2773787_3 Dehydrogenase K11337 - 1.1.1.396 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 436.0
TLS3_k127_2773787_4 Belongs to the FPP GGPP synthase family K13789 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 340.0
TLS3_k127_2773787_5 COG0500 SAM-dependent methyltransferases K09846 - 2.1.1.210 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 344.0
TLS3_k127_2773787_6 hydroxyneurosporene synthase K09844 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016122,GO:0016123,GO:0016829,GO:0016835,GO:0016836,GO:0018904,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046148,GO:0071704,GO:1901178,GO:1901180,GO:1901503,GO:1901576 4.2.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002921 282.0
TLS3_k127_2814608_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 578.0
TLS3_k127_2814608_1 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 527.0
TLS3_k127_2814608_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 508.0
TLS3_k127_2814608_3 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 479.0
TLS3_k127_2814608_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 394.0
TLS3_k127_2814608_5 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005941 285.0
TLS3_k127_2814608_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000008724 250.0
TLS3_k127_2814608_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000002006 173.0
TLS3_k127_2814608_9 Domain of unknown function (DUF1127) - - - 0.00000003119 59.0
TLS3_k127_28272_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 558.0
TLS3_k127_28272_1 PFAM peptidase S10 serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 471.0
TLS3_k127_28272_2 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 383.0
TLS3_k127_28272_3 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 321.0
TLS3_k127_28272_4 Protein of unknown function (DUF3775) - - - 0.0000000000000000004584 102.0
TLS3_k127_28272_5 Protein of unknwon function (DUF3008) - - - 0.000000000001782 78.0
TLS3_k127_2834575_0 N terminal of Calcineurin-like phosphoesterase - - - 2.555e-278 872.0
TLS3_k127_2834575_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 304.0
TLS3_k127_2834575_2 OmpA family K03286 - - 0.000006251 56.0
TLS3_k127_2852180_0 N-acetylmuramidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002833 266.0
TLS3_k127_2852180_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000005283 224.0
TLS3_k127_2852180_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000008376 173.0
TLS3_k127_2852180_3 Putative peptidoglycan binding domain - - - 0.0000000004211 70.0
TLS3_k127_2853751_0 Mannitol dehydrogenase K00040 - 1.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 542.0
TLS3_k127_2853751_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 413.0
TLS3_k127_2853751_2 Hydrolase Family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 411.0
TLS3_k127_2853751_3 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000003763 175.0
TLS3_k127_2853751_4 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000002393 102.0
TLS3_k127_2858429_0 COG4584 Transposase and inactivated derivatives - - - 5.726e-223 701.0
TLS3_k127_2858429_1 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 491.0
TLS3_k127_2858429_2 Belongs to the 'phage' integrase family - - - 0.00000000000008145 72.0
TLS3_k127_2866900_0 COG4584 Transposase and inactivated derivatives - - - 4.741e-222 698.0
TLS3_k127_2866900_1 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 359.0
TLS3_k127_2866900_2 Protein of unknown function (DUF3987) - - - 0.000000002439 61.0
TLS3_k127_2873520_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1249.0
TLS3_k127_2873520_1 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
TLS3_k127_2873520_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000007031 134.0
TLS3_k127_2877961_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 423.0
TLS3_k127_2877961_1 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000008403 218.0
TLS3_k127_2915790_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 1.052e-267 829.0
TLS3_k127_2915790_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 6.688e-226 710.0
TLS3_k127_2915790_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.871e-198 627.0
TLS3_k127_2915790_3 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 428.0
TLS3_k127_2915790_4 ATPases associated with a variety of cellular activities K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 363.0
TLS3_k127_2915790_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000005586 215.0
TLS3_k127_2915790_6 colicin V production K03558 - - 0.0000000000000000000000000000000000000000000000000001873 199.0
TLS3_k127_2915790_7 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000007966 152.0
TLS3_k127_2919474_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 551.0
TLS3_k127_2919474_1 Beta-lactamase K18988 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 525.0
TLS3_k127_2919474_2 Beta-lactamase K18988 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 471.0
TLS3_k127_2919474_3 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 471.0
TLS3_k127_2919474_4 Protein of unknown function (DUF1269) - - - 0.000000000000000000000000000000000000000000000001467 176.0
TLS3_k127_2927306_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.113e-269 846.0
TLS3_k127_2927306_1 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 318.0
TLS3_k127_2927306_2 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003396 276.0
TLS3_k127_2927306_3 DNA mismatch endonuclease Vsr K07458 - - 0.0000000000000000000000000000000000000000001736 169.0
TLS3_k127_2927306_4 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.0000000000000000000000000000006041 124.0
TLS3_k127_2927306_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000007071 104.0
TLS3_k127_2927306_6 - - - - 0.0002127 46.0
TLS3_k127_2939715_0 EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000003865 216.0
TLS3_k127_2939715_1 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000001365 189.0
TLS3_k127_2939715_2 PFAM PHB accumulation regulatory domain - - - 0.000000000000000000000000004225 114.0
TLS3_k127_2939715_3 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000008144 98.0
TLS3_k127_2939715_5 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.000213 46.0
TLS3_k127_2981688_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 4.443e-222 704.0
TLS3_k127_2981688_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 321.0
TLS3_k127_2981688_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 312.0
TLS3_k127_2981688_3 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000002701 143.0
TLS3_k127_2981688_4 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000001318 110.0
TLS3_k127_298748_0 C-methyltransferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 587.0
TLS3_k127_298748_1 Domain of unknown function (DUF2172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 543.0
TLS3_k127_298748_2 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 438.0
TLS3_k127_298748_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 389.0
TLS3_k127_298748_4 Mycolic acid cyclopropane synthetase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 287.0
TLS3_k127_298748_5 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001304 276.0
TLS3_k127_298748_6 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000002972 141.0
TLS3_k127_2988474_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 423.0
TLS3_k127_2988474_1 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 294.0
TLS3_k127_2988474_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000002096 165.0
TLS3_k127_2991841_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 493.0
TLS3_k127_2991841_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 398.0
TLS3_k127_2991841_2 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000008727 231.0
TLS3_k127_2993573_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 352.0
TLS3_k127_2993573_1 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001535 264.0
TLS3_k127_3004359_0 PFAM ABC transporter K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 503.0
TLS3_k127_3004359_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 355.0
TLS3_k127_3004359_2 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006408 259.0
TLS3_k127_3007769_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002544 239.0
TLS3_k127_3007769_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000005146 217.0
TLS3_k127_3007769_2 - - - - 0.00000000000000000000000000000000000000000000000000000006575 203.0
TLS3_k127_3008654_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 313.0
TLS3_k127_3008654_1 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001348 252.0
TLS3_k127_3008654_2 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000007217 177.0
TLS3_k127_3011911_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 279.0
TLS3_k127_3011911_1 PFAM CreA family protein K05805 - - 0.000000000000000000000000000000000000000000000000000000000002992 213.0
TLS3_k127_3011911_2 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000000000000007499 203.0
TLS3_k127_3011911_3 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000001295 123.0
TLS3_k127_3011911_4 Protein of unknown function (DUF2842) - - - 0.000000000000000000000002609 106.0
TLS3_k127_3074426_0 Zinc-binding dehydrogenase K00001,K19745 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 490.0
TLS3_k127_3074426_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 415.0
TLS3_k127_3074426_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000756 220.0
TLS3_k127_3074426_3 - - - - 0.000000000000008076 77.0
TLS3_k127_3104614_0 FAD binding domain K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 530.0
TLS3_k127_3104614_1 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 402.0
TLS3_k127_3111985_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 343.0
TLS3_k127_3111985_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 286.0
TLS3_k127_3111985_2 Belongs to the DnaA family - - - 0.00000000000000000000000000286 116.0
TLS3_k127_3124784_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.896e-260 811.0
TLS3_k127_3124784_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 522.0
TLS3_k127_3124784_2 YjbR - - - 0.000000000000000000000000000000000000001424 153.0
TLS3_k127_3124784_3 Squalene/phytoene synthase K02291,K18163 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000005051 154.0
TLS3_k127_3138353_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 502.0
TLS3_k127_3138353_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000003714 162.0
TLS3_k127_3138353_2 ATP synthase subunit C K02124 - - 0.0000000000000000000000000003959 132.0
TLS3_k127_3138353_3 subunit c K02124 - - 0.000000000000001058 77.0
TLS3_k127_3138353_4 subunit D K02120 - - 0.000000000002865 67.0
TLS3_k127_3138882_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1044.0
TLS3_k127_3138882_1 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 389.0
TLS3_k127_3138882_2 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002592 269.0
TLS3_k127_3138882_3 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006111 252.0
TLS3_k127_3138882_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002871 236.0
TLS3_k127_3138882_5 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.0000000000000000000000000000000000000000000000000000000000002574 220.0
TLS3_k127_3138882_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0005671 49.0
TLS3_k127_3165098_0 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 592.0
TLS3_k127_3165098_1 transporter substrate-binding protein K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 452.0
TLS3_k127_3165098_2 FGGY family of carbohydrate kinases, C-terminal domain K00854 GO:0003674,GO:0003824,GO:0004856,GO:0005975,GO:0005996,GO:0005997,GO:0005998,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:1901575 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 320.0
TLS3_k127_3165098_3 Domain of unknown function (DUF1850) - - - 0.0000000000000000000000002165 123.0
TLS3_k127_3174783_0 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1032.0
TLS3_k127_3174783_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000007591 163.0
TLS3_k127_3174783_2 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000000000001558 122.0
TLS3_k127_3194031_0 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.916e-264 819.0
TLS3_k127_3194031_1 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000000000003658 159.0
TLS3_k127_3194031_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000003229 153.0
TLS3_k127_3195333_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 4.539e-266 831.0
TLS3_k127_3195333_1 - - - - 0.00000000000000000000000166 108.0
TLS3_k127_3232051_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.01e-219 704.0
TLS3_k127_3232051_1 Cell wall formation K00075,K01921 - 1.3.1.98,6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 477.0
TLS3_k127_3232051_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 415.0
TLS3_k127_3232051_3 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 418.0
TLS3_k127_3232051_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 309.0
TLS3_k127_3232051_5 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001798 255.0
TLS3_k127_3232051_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000001527 164.0
TLS3_k127_3232051_7 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000001093 161.0
TLS3_k127_32382_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.051e-221 704.0
TLS3_k127_32382_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 323.0
TLS3_k127_32382_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000005774 187.0
TLS3_k127_32382_3 Major facilitator superfamily - - - 0.000000000000000000000000000002288 136.0
TLS3_k127_3239397_0 A predicted alpha-helical domain with a conserved ER motif. - - - 4.821e-249 780.0
TLS3_k127_3239397_1 transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 417.0
TLS3_k127_3239592_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1814.0
TLS3_k127_3239592_1 PFAM glucose-methanol-choline oxidoreductase K00108 - 1.1.99.1 7.443e-238 756.0
TLS3_k127_3239592_10 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000002405 147.0
TLS3_k127_3239592_11 - - - - 0.0000000000000000000000000004388 124.0
TLS3_k127_3239592_12 Staphylococcal nuclease homologues - - - 0.00000000000009568 82.0
TLS3_k127_3239592_13 Peptidase propeptide and YPEB domain - - - 0.0000004037 55.0
TLS3_k127_3239592_2 AMP-binding enzyme C-terminal domain K01897,K01904 - 6.2.1.12,6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 532.0
TLS3_k127_3239592_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 371.0
TLS3_k127_3239592_4 transferase activity, transferring acyl groups other than amino-acyl groups K11941 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0008150,GO:0008152,GO:0009311,GO:0016020,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0044238,GO:0044464,GO:0071704,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 348.0
TLS3_k127_3239592_5 COG0517 FOG CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000009533 236.0
TLS3_k127_3239592_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000003425 211.0
TLS3_k127_3239592_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000001061 210.0
TLS3_k127_3239592_8 cytochrome - - - 0.0000000000000000000000000000000000000000000000000001277 195.0
TLS3_k127_3239592_9 COG2771 DNA-binding HTH domain-containing proteins - - - 0.000000000000000000000000000000000000000009126 161.0
TLS3_k127_3240945_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 316.0
TLS3_k127_3240945_1 oligoketide cyclase lipid transport protein K18588 - - 0.0000000000000000000000001809 117.0
TLS3_k127_3257814_0 COG1192 ATPases involved in chromosome partitioning K03496 - - 6.215e-233 729.0
TLS3_k127_3257814_1 Replication initiator protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 432.0
TLS3_k127_3257814_2 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000004794 236.0
TLS3_k127_3257814_3 Resolvase - - - 0.000000000001727 72.0
TLS3_k127_3257814_4 Right handed beta helix region - - - 0.00002547 56.0
TLS3_k127_3265348_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 367.0
TLS3_k127_3265348_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 317.0
TLS3_k127_3265348_2 pfkB family carbohydrate kinase K00882,K16370 - 2.7.1.11,2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000007712 245.0
TLS3_k127_3280905_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 327.0
TLS3_k127_3280905_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000001033 196.0
TLS3_k127_3280905_2 - - - - 0.00000000002571 67.0
TLS3_k127_3280905_3 - - - - 0.00009733 46.0
TLS3_k127_3299215_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459,K11206 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 359.0
TLS3_k127_3299215_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000002181 190.0
TLS3_k127_3299215_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000005654 138.0
TLS3_k127_3299215_3 Phosphoribosyl transferase domain - - - 0.0000000001788 62.0
TLS3_k127_3299480_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.671e-306 967.0
TLS3_k127_3299480_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002178 273.0
TLS3_k127_3304287_0 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 608.0
TLS3_k127_3304287_1 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.000000000000000000003342 93.0
TLS3_k127_3338777_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 609.0
TLS3_k127_3338777_1 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 368.0
TLS3_k127_3338777_2 - - - - 0.0009758 51.0
TLS3_k127_3344199_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 1.499e-252 786.0
TLS3_k127_3344199_1 membrane - - - 1.179e-248 786.0
TLS3_k127_3344199_2 Aerotolerance regulator N-terminal - - - 4.762e-247 781.0
TLS3_k127_3344199_3 Protein of unknown function (DUF3253) - - - 0.0001071 55.0
TLS3_k127_3344846_0 Flagella basal body rod protein K02392 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 405.0
TLS3_k127_3344846_1 Flagellar basal body rod FlgEFG protein C-terminal K02391,K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000189 257.0
TLS3_k127_3344846_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000000000000000000000000000000000000000009485 222.0
TLS3_k127_3344846_3 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000000000000000000000000009544 141.0
TLS3_k127_3344846_4 Controls the rotational direction of flagella during chemotaxis - - - 0.0006963 48.0
TLS3_k127_335393_0 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00050,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 332.0
TLS3_k127_335393_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 322.0
TLS3_k127_335393_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006856 254.0
TLS3_k127_335393_3 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000007969 226.0
TLS3_k127_335393_4 PFAM DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000006241 188.0
TLS3_k127_335393_5 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000000000000000421 184.0
TLS3_k127_335393_6 Membrane fusogenic activity K09806 - - 0.0000000000000000000000000003336 124.0
TLS3_k127_335393_7 Phasin protein - - - 0.00000000000000000001385 99.0
TLS3_k127_3356207_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001452 287.0
TLS3_k127_3356207_1 Hydrolase, carbon-nitrogen family - - - 0.0000000000000000000000000000000000000001985 155.0
TLS3_k127_3356207_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000149 140.0
TLS3_k127_3356207_3 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000001064 112.0
TLS3_k127_3374645_0 DNA helicase K03657 - 3.6.4.12 0.0 1182.0
TLS3_k127_3374645_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 2.912e-203 637.0
TLS3_k127_3374645_2 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 5.956e-195 634.0
TLS3_k127_3374645_3 Domain of unknown function (DUF378) K09779 - - 0.00000000000000000000000004121 113.0
TLS3_k127_3374645_4 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000223 90.0
TLS3_k127_3374645_5 Peptidase propeptide and YPEB domain - - - 0.0000000000000006068 82.0
TLS3_k127_3380509_0 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 417.0
TLS3_k127_3380509_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 398.0
TLS3_k127_3380509_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 355.0
TLS3_k127_3380509_3 Virulence-associated protein E - - - 0.0000000000000000000000000000000000000000000000008976 177.0
TLS3_k127_3380509_4 transport system auxiliary component K18480 - - 0.00000000000000000000000000000002836 143.0
TLS3_k127_3384456_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.77e-210 677.0
TLS3_k127_3384456_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 447.0
TLS3_k127_3384456_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 314.0
TLS3_k127_3389121_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 383.0
TLS3_k127_3389121_1 polyphosphate kinase K22468 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0042802,GO:0044237 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 357.0
TLS3_k127_3389121_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001056 206.0
TLS3_k127_3389121_3 membrane protein domain - - - 0.0000000000000000000000000000000000808 138.0
TLS3_k127_3393610_0 GTA TIM-barrel-like domain - - - 0.0 1217.0
TLS3_k127_3393610_1 Protein of unknown function (DUF2927) - - - 0.00000000000000000007748 95.0
TLS3_k127_3393610_2 - - - - 0.0000007809 59.0
TLS3_k127_3396919_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.153e-294 919.0
TLS3_k127_3396919_1 Animal haem peroxidase K19511 - 1.11.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 454.0
TLS3_k127_3396919_2 FlhB HrpN YscU SpaS Family K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 333.0
TLS3_k127_3396919_3 Bacterial export proteins, family 1 K02421 - - 0.00000000000000000000000000000000000000000000000000000000000000029 230.0
TLS3_k127_3396919_4 soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000003978 197.0
TLS3_k127_3396990_0 ABC-type sugar transport system periplasmic component K17315 - - 7.439e-212 664.0
TLS3_k127_3396990_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 9.704e-197 634.0
TLS3_k127_3396990_2 ABC-type sugar transport systems permease components K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 506.0
TLS3_k127_3396990_3 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 407.0
TLS3_k127_3396990_4 ABC-type sugar transport system, permease component K02026,K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 341.0
TLS3_k127_3396990_5 SnoaL-like polyketide cyclase K21700 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 316.0
TLS3_k127_3397293_0 Uracil-DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007747 583.0
TLS3_k127_3397293_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000002575 191.0
TLS3_k127_3397293_2 - - - - 0.00000000000009697 81.0
TLS3_k127_3405422_0 COG0772 Bacterial cell division membrane protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 556.0
TLS3_k127_3405422_1 - - - - 0.0000000000000000000000000000000000000000003106 173.0
TLS3_k127_3405422_2 Dodecin K09165 - - 0.00000000000000000000189 95.0
TLS3_k127_3405422_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000001519 83.0
TLS3_k127_3414485_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 5.97e-288 927.0
TLS3_k127_3414485_1 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 409.0
TLS3_k127_3422561_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 417.0
TLS3_k127_3422561_1 COG1145 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001253 246.0
TLS3_k127_3422561_2 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000009 168.0
TLS3_k127_3457828_0 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K01144 - 3.1.11.5 5.943e-214 675.0
TLS3_k127_3457828_1 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 499.0
TLS3_k127_3457828_10 Phospholipase Carboxylesterase K06999 - - 0.000000000000000000001542 109.0
TLS3_k127_3457828_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 490.0
TLS3_k127_3457828_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 388.0
TLS3_k127_3457828_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 361.0
TLS3_k127_3457828_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 359.0
TLS3_k127_3457828_6 Ion transport protein K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 345.0
TLS3_k127_3457828_7 Acyl-homoserine-lactone synthase K20249 - 2.3.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 287.0
TLS3_k127_3457828_8 transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007341 249.0
TLS3_k127_3457828_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000006479 176.0
TLS3_k127_3464025_0 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 353.0
TLS3_k127_3464025_1 TIGRFAM 5,10-methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 338.0
TLS3_k127_3464025_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000004595 185.0
TLS3_k127_3464025_3 Virulence factor - - - 0.0000000000000000000000000000000000001502 145.0
TLS3_k127_3464025_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000282 98.0
TLS3_k127_3470764_0 Domain of unknown function (DUF4432) - - - 8.414e-196 617.0
TLS3_k127_3470764_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 617.0
TLS3_k127_3470764_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 368.0
TLS3_k127_3490895_0 Dehydratase large subunit K01699 - 4.2.1.28 0.0 1118.0
TLS3_k127_3490895_1 ABC-type sugar transport system periplasmic component K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 490.0
TLS3_k127_3490895_10 Dehydratase small subunit - - - 0.0000000000000000000000000000000000114 157.0
TLS3_k127_3490895_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 471.0
TLS3_k127_3490895_3 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 417.0
TLS3_k127_3490895_4 Binding-protein-dependent transport system inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 421.0
TLS3_k127_3490895_5 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 392.0
TLS3_k127_3490895_6 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 390.0
TLS3_k127_3490895_7 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 362.0
TLS3_k127_3490895_8 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 349.0
TLS3_k127_3490895_9 helix_turn _helix lactose operon repressor K03435 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 340.0
TLS3_k127_3506881_0 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000003561 249.0
TLS3_k127_3506881_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000001708 216.0
TLS3_k127_3506881_2 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000007438 216.0
TLS3_k127_3508912_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 388.0
TLS3_k127_3508912_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 359.0
TLS3_k127_3508912_2 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002704 246.0
TLS3_k127_3509022_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.944e-210 661.0
TLS3_k127_3509022_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.596e-207 658.0
TLS3_k127_3509022_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 385.0
TLS3_k127_3509022_3 COG4942 Membrane-bound metallopeptidase - - - 0.00000000000000000000000000000000000000000000000000000001814 224.0
TLS3_k127_3509022_4 PFAM Cold-shock K03704 - - 0.00000000000000000000000000000000000000000000000007775 184.0
TLS3_k127_3509022_5 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000001933 101.0
TLS3_k127_3509022_6 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000001067 66.0
TLS3_k127_350997_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 512.0
TLS3_k127_350997_1 effector of murein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003457 278.0
TLS3_k127_350997_2 PFAM LrgA K06518 - - 0.0000000000000000000001949 107.0
TLS3_k127_350997_3 Sulfotransferase family - - - 0.000000002954 69.0
TLS3_k127_3510531_0 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 417.0
TLS3_k127_3510531_1 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 368.0
TLS3_k127_3510531_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
TLS3_k127_3510531_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 305.0
TLS3_k127_3510531_4 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006521 276.0
TLS3_k127_3510531_5 Domain of unknown function (DU1801) - - - 0.00000000000508 75.0
TLS3_k127_3511863_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 - 2.7.7.7 1.209e-320 996.0
TLS3_k127_3511863_1 - - - - 0.000003045 57.0
TLS3_k127_3518162_0 PFAM ABC transporter related K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 586.0
TLS3_k127_3518162_1 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 441.0
TLS3_k127_3518162_2 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 426.0
TLS3_k127_3518162_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000204 289.0
TLS3_k127_3518162_4 asparagine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000271 278.0
TLS3_k127_3518162_5 5-formyltetrahydrofolate cyclo-ligase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001345 265.0
TLS3_k127_3518162_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
TLS3_k127_3518162_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004841 225.0
TLS3_k127_3518162_8 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000167 183.0
TLS3_k127_3518162_9 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000005537 162.0
TLS3_k127_3526102_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.0 1172.0
TLS3_k127_3526102_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 456.0
TLS3_k127_3526102_2 Xanthine dehydrogenase K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 351.0
TLS3_k127_3526102_3 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007042 259.0
TLS3_k127_3531026_0 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate K00899 - 2.7.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 548.0
TLS3_k127_3531026_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 339.0
TLS3_k127_3531026_2 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000843 243.0
TLS3_k127_3531026_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000006697 98.0
TLS3_k127_3542214_0 DEAD-like helicases superfamily K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 4.335e-311 967.0
TLS3_k127_3542214_1 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
TLS3_k127_3542214_2 L,D-transpeptidase catalytic domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000001097 219.0
TLS3_k127_3542214_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000001957 207.0
TLS3_k127_3542214_4 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000009682 126.0
TLS3_k127_3542214_5 - - - - 0.0000000000000000000000008555 108.0
TLS3_k127_3542214_6 - - - - 0.00000000000003003 81.0
TLS3_k127_3557989_0 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 381.0
TLS3_k127_3557989_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 349.0
TLS3_k127_3557989_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.0000000000000000000000007286 109.0
TLS3_k127_3557989_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.0000000000000000000002097 102.0
TLS3_k127_3575938_0 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000002862 196.0
TLS3_k127_3575938_1 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000004466 153.0
TLS3_k127_3575938_2 MatE K03327 - - 0.00000000000000000000000000108 121.0
TLS3_k127_3575938_3 UPF0056 membrane protein K05595 - - 0.00000000000335 67.0
TLS3_k127_3579482_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00219 - 1.3.1.34 1.292e-265 826.0
TLS3_k127_3579482_1 membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 469.0
TLS3_k127_3587475_0 ABC-type multidrug transport system ATPase and permease K06147,K18893 - - 1.17e-238 752.0
TLS3_k127_3587475_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 525.0
TLS3_k127_3587475_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 393.0
TLS3_k127_3587475_3 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 291.0
TLS3_k127_3587475_4 Phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000006333 241.0
TLS3_k127_3587475_5 - - - - 0.0000000000000000000000000000000000000000000006298 171.0
TLS3_k127_3587475_6 Protein of unknown function (DUF3618) - - - 0.00000000000000000000000000000000000000000002543 179.0
TLS3_k127_3587475_7 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000000000000000002464 147.0
TLS3_k127_3587475_8 - - - - 0.000000000000000001907 96.0
TLS3_k127_3598455_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000556 241.0
TLS3_k127_3614529_0 Bacterial extracellular solute-binding protein K02027 - - 1.607e-237 743.0
TLS3_k127_3614529_1 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 533.0
TLS3_k127_3614529_10 Dihydroxyacetone kinase, phosphotransfer K05881 - 2.7.1.121 0.00000000000000000000000000000000000000001606 164.0
TLS3_k127_3614529_11 sugar phosphatases of the HAD superfamily - - - 0.000000000000000000006753 100.0
TLS3_k127_3614529_12 PTS HPr component phosphorylation site K11189 - - 0.0000000000000003412 90.0
TLS3_k127_3614529_2 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 521.0
TLS3_k127_3614529_3 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 450.0
TLS3_k127_3614529_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 436.0
TLS3_k127_3614529_5 Binding-protein-dependent transport system inner membrane component K02026,K10229 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 441.0
TLS3_k127_3614529_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 381.0
TLS3_k127_3614529_7 Aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 305.0
TLS3_k127_3614529_8 Putative sugar-binding domain K00863 - 2.7.1.28,2.7.1.29,4.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000005896 266.0
TLS3_k127_3614529_9 Dak2 - - - 0.000000000000000000000000000000000000000000000000005138 188.0
TLS3_k127_3626947_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 521.0
TLS3_k127_3626947_1 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 393.0
TLS3_k127_3626947_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000006638 228.0
TLS3_k127_3626947_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000002253 139.0
TLS3_k127_3626947_4 Belongs to the UPF0260 family K09160 - - 0.000000000000000000002172 94.0
TLS3_k127_3626947_5 GCN5 family acetyltransferase - - - 0.000000000000001028 91.0
TLS3_k127_3631137_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 1.172e-205 653.0
TLS3_k127_3631137_1 ABC transporter substrate-binding protein K02035 - - 3.109e-202 663.0
TLS3_k127_3631137_10 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001016 246.0
TLS3_k127_3631137_11 bleomycin resistance protein - - - 0.000000000000000000000000000000000000000000000003944 178.0
TLS3_k127_3631137_12 - - - - 0.0000000000000000000000000000000002651 139.0
TLS3_k127_3631137_13 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000001658 128.0
TLS3_k127_3631137_14 Major facilitator superfamily - - - 0.000000000000000000000000003666 128.0
TLS3_k127_3631137_15 Transglycosylase associated protein - - - 0.0000000000000000000000002987 108.0
TLS3_k127_3631137_16 Transglycosylase associated protein - - - 0.000000000000000000004979 95.0
TLS3_k127_3631137_17 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.0000000000000000001166 102.0
TLS3_k127_3631137_18 - - - - 0.000002475 61.0
TLS3_k127_3631137_2 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 612.0
TLS3_k127_3631137_3 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 596.0
TLS3_k127_3631137_4 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 523.0
TLS3_k127_3631137_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 476.0
TLS3_k127_3631137_6 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 477.0
TLS3_k127_3631137_7 Flavin containing amine oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 422.0
TLS3_k127_3631137_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 426.0
TLS3_k127_3631137_9 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 396.0
TLS3_k127_3648916_0 TIGRFAM polyhydroxyalkanoate depolymerase, intracellular K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 490.0
TLS3_k127_3648916_1 PFAM conserved - - - 0.000000000000000000000008988 106.0
TLS3_k127_3648916_2 - - - - 0.00000695 52.0
TLS3_k127_3648916_3 Protein of unknown function DUF45 K07043 - - 0.00003883 53.0
TLS3_k127_3672_0 ATPases associated with a variety of cellular activities K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 484.0
TLS3_k127_3672_1 ATPases associated with a variety of cellular activities K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 295.0
TLS3_k127_3672_2 FAD-NAD(P)-binding K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001213 256.0
TLS3_k127_3672_3 FAD-NAD(P)-binding K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000007455 234.0
TLS3_k127_3672_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000004023 57.0
TLS3_k127_3674805_0 Glycine cleavage system T protein K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 501.0
TLS3_k127_3674805_1 Iron-regulated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002907 284.0
TLS3_k127_3674805_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000009813 183.0
TLS3_k127_3689479_0 Protein conserved in bacteria K09987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 336.0
TLS3_k127_3689479_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00076 - 1.1.1.159 0.000000000000000000000000000000000000000000000000000000000000144 230.0
TLS3_k127_3689479_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000008008 154.0
TLS3_k127_3689479_3 Ribonuclease T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.0000000000000000000000000000000000000001061 167.0
TLS3_k127_3707624_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.615e-247 775.0
TLS3_k127_3707624_1 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000004399 159.0
TLS3_k127_3715857_0 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 427.0
TLS3_k127_3715857_1 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 430.0
TLS3_k127_3715857_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 344.0
TLS3_k127_3715857_3 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007009 277.0
TLS3_k127_3715857_4 Putative sugar-binding N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006379 229.0
TLS3_k127_3715857_5 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.0000000000000000000000000002016 114.0
TLS3_k127_3724550_0 protein conserved in bacteria K07793 - - 1.667e-263 818.0
TLS3_k127_3724550_1 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000000000000000000000000000009821 162.0
TLS3_k127_3724550_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000009842 143.0
TLS3_k127_3726017_0 Methyltransferase K14083 - 2.1.1.250 2.024e-244 766.0
TLS3_k127_3726017_1 Type I phosphodiesterase / nucleotide pyrophosphatase K01133 - 3.1.6.6 7.61e-237 742.0
TLS3_k127_3726017_2 PFAM ABC transporter K02471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 533.0
TLS3_k127_3726017_3 ABC-type proline glycine betaine transport systems, periplasmic components K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 417.0
TLS3_k127_3726017_4 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 406.0
TLS3_k127_3726017_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 374.0
TLS3_k127_3726017_6 Pyruvate phosphate dikinase K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000003719 249.0
TLS3_k127_3726017_7 Cupin - - - 0.000000000000000000000000000000000000000000000000001087 192.0
TLS3_k127_3726017_8 Pectate lyase superfamily protein - - - 0.00000000000000000000000000000000000006266 149.0
TLS3_k127_3726017_9 Domain of unknown function (DUF4864) - - - 0.000000000000000000000000000000002216 134.0
TLS3_k127_3733830_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1248.0
TLS3_k127_3733830_1 FtsX-like permease family K02004 - - 4.129e-241 780.0
TLS3_k127_3733830_10 Rhomboid family - - - 0.00000000000000000000000000000000000000000001641 173.0
TLS3_k127_3733830_11 Esterase-like activity of phytase - - - 0.000000000000000000002156 102.0
TLS3_k127_3733830_2 PFAM phospholipase D K06131 - - 1.619e-202 641.0
TLS3_k127_3733830_3 secreted hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 476.0
TLS3_k127_3733830_4 Animal haem peroxidase K19511 - 1.11.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 435.0
TLS3_k127_3733830_5 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 347.0
TLS3_k127_3733830_6 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 323.0
TLS3_k127_3733830_7 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 307.0
TLS3_k127_3733830_8 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004661 286.0
TLS3_k127_3733830_9 Uncharacterized protein conserved in bacteria (DUF2237) - - - 0.000000000000000000000000000000000000000000000001918 177.0
TLS3_k127_3744139_0 COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 1.98e-216 689.0
TLS3_k127_3744139_1 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000008748 150.0
TLS3_k127_3753839_0 COG1291 Flagellar motor component K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 437.0
TLS3_k127_3753839_1 PFAM MgtE intracellular - - - 0.000000000000000000000000000004513 126.0
TLS3_k127_3753839_2 belongs to the thioredoxin family - - - 0.00000005827 63.0
TLS3_k127_3753839_3 - - - - 0.00000006961 61.0
TLS3_k127_3754570_0 Iron-sulfur cluster-binding domain K06139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 557.0
TLS3_k127_3754570_1 Catalyzes the formation of succinate from succinate semialdehyde K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 515.0
TLS3_k127_3754570_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06136,K06137,K06138 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 338.0
TLS3_k127_3754570_3 coenzyme PQQ synthesis K06138 - - 0.000000000000000000000000009941 122.0
TLS3_k127_3770605_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 326.0
TLS3_k127_3770605_1 (GMC) oxidoreductase - - - 0.0000000000000000000000000000000000000001072 164.0
TLS3_k127_3770605_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000002151 136.0
TLS3_k127_3784593_0 Belongs to the glycosyl hydrolase 13 family K02438 - 3.2.1.196 8.152e-245 788.0
TLS3_k127_3784593_1 Phosphoglucomutase K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005982,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009581,GO:0009582,GO:0009590,GO:0009605,GO:0009628,GO:0009629,GO:0009941,GO:0009987,GO:0010319,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019252,GO:0019318,GO:0019320,GO:0019388,GO:0031967,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046365,GO:0048046,GO:0050896,GO:0051606,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 1.648e-243 758.0
TLS3_k127_3784593_2 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 475.0
TLS3_k127_3784593_3 Glycosyl transferase family 21 K03669 GO:0005575,GO:0016020 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 399.0
TLS3_k127_3787146_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.297e-238 746.0
TLS3_k127_3787146_1 Anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000005118 229.0
TLS3_k127_3804109_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 521.0
TLS3_k127_3804109_1 Tetratricopeptide repeat K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 344.0
TLS3_k127_3804109_2 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 309.0
TLS3_k127_3804109_3 hydrolases of HD superfamily K06952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002028 287.0
TLS3_k127_3804109_4 Stringent starvation protein B K09985 - - 0.000000000000000000000000000000000000000000000001067 182.0
TLS3_k127_3804109_5 response to pH - - - 0.000000000000000000000001988 106.0
TLS3_k127_3804109_6 Belongs to the UPF0434 family K09791 - - 0.00000000000000002188 96.0
TLS3_k127_3804109_7 Cysteine rich repeat K06816 - - 0.0006819 50.0
TLS3_k127_3807426_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1017.0
TLS3_k127_3807426_1 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 0.0 1009.0
TLS3_k127_3807426_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 589.0
TLS3_k127_3807426_3 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 364.0
TLS3_k127_3807426_4 Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione K03396 - 4.4.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 336.0
TLS3_k127_3807426_5 CobW/HypB/UreG, nucleotide-binding domain K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 335.0
TLS3_k127_3807426_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000003034 242.0
TLS3_k127_3807426_7 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000003417 216.0
TLS3_k127_3807426_8 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000000000000000001155 175.0
TLS3_k127_3807426_9 Ami_3 K01448 - 3.5.1.28 0.000000000000000805 80.0
TLS3_k127_3819592_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 507.0
TLS3_k127_3819592_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 376.0
TLS3_k127_3856280_0 Domain of unknown function (DUF3390) K18929 - - 7.4e-212 676.0
TLS3_k127_3856280_1 Transglycosylase SLT domain K00786,K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008589 514.0
TLS3_k127_3856280_2 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 336.0
TLS3_k127_3856280_3 Glycosyl hydrolases family 25 K07273 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 297.0
TLS3_k127_3856280_4 LUD domain K00782 - - 0.000000000000000000000000000000000000002968 168.0
TLS3_k127_3856280_5 Potassium channel protein - - - 0.00000000000000000000002921 113.0
TLS3_k127_3864305_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 2.344e-219 688.0
TLS3_k127_3864305_1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K21826 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 452.0
TLS3_k127_3864305_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 340.0
TLS3_k127_3864305_3 SBF-like CPA transporter family (DUF4137) K03325 - - 0.00000000000000000000000000000001018 135.0
TLS3_k127_3891011_0 GMC oxidoreductase - - - 3.659e-294 907.0
TLS3_k127_3891011_1 NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit K05565 GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 2.088e-218 703.0
TLS3_k127_3891011_10 Na H antiporter K05571 - - 0.000000000000000000000001728 108.0
TLS3_k127_3891011_11 Multisubunit Na H antiporter, MnhF subunit K05570 - - 0.0000000002642 66.0
TLS3_k127_3891011_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 547.0
TLS3_k127_3891011_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 419.0
TLS3_k127_3891011_4 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009535 249.0
TLS3_k127_3891011_5 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000006147 218.0
TLS3_k127_3891011_6 Multisubunit Na H antiporter, MnhC subunit K05567 - - 0.000000000000000000000000000000000000002475 149.0
TLS3_k127_3891011_7 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05566 - - 0.0000000000000000000000000000000005013 152.0
TLS3_k127_3891011_8 protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis - - - 0.00000000000000000000000000000004857 136.0
TLS3_k127_3891011_9 Multisubunit Na H antiporter, MnhE subunit K05569 - - 0.0000000000000000000000001225 123.0
TLS3_k127_3901386_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.261e-236 749.0
TLS3_k127_3901386_1 PFAM manganese containing catalase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 536.0
TLS3_k127_3901386_2 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 467.0
TLS3_k127_3901386_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 373.0
TLS3_k127_3901386_4 with different specificities (related to short-chain alcohol K00019,K18335 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 362.0
TLS3_k127_3901386_5 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000762 282.0
TLS3_k127_3901386_6 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001036 269.0
TLS3_k127_3901386_7 Divalent ion tolerance protein K03926 - - 0.0000000000000000000005809 101.0
TLS3_k127_3910963_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 594.0
TLS3_k127_3910963_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 409.0
TLS3_k127_3910963_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 389.0
TLS3_k127_3910963_3 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000006966 227.0
TLS3_k127_3910963_4 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000697 205.0
TLS3_k127_3910963_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000001715 193.0
TLS3_k127_3910963_6 - - - - 0.0000000000000000000002275 107.0
TLS3_k127_3911481_0 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000000000000000000004087 229.0
TLS3_k127_3911481_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000005432 218.0
TLS3_k127_3911481_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.000000000000000000000000000000000000000000000000002635 189.0
TLS3_k127_3911481_3 small protein containing a coiled-coil domain - - - 0.0000000000000000005022 89.0
TLS3_k127_3911481_4 Protein of unknown function (DUF1150) - - - 0.000000000000002607 86.0
TLS3_k127_3924779_0 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 376.0
TLS3_k127_3924779_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000591 124.0
TLS3_k127_3924779_2 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000004539 78.0
TLS3_k127_3924779_3 - - - - 0.0001627 48.0
TLS3_k127_3928947_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1506.0
TLS3_k127_3928947_1 COG3239 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 355.0
TLS3_k127_3928947_2 Dmso reductase anchor subunit K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 304.0
TLS3_k127_3928947_3 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000007545 213.0
TLS3_k127_3928947_4 membrane K08990 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000003307 186.0
TLS3_k127_3928947_5 pfam nudix - - - 0.00000000000000000000000000000000000113 147.0
TLS3_k127_3931221_0 ABC transporter K17210 - - 1.097e-244 764.0
TLS3_k127_3931221_1 Belongs to the binding-protein-dependent transport system permease family K10440,K17209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 514.0
TLS3_k127_3931221_2 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 386.0
TLS3_k127_3931221_3 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
TLS3_k127_3931221_4 TOBE domain K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003829 248.0
TLS3_k127_3938507_0 Phosphate acetyl butaryl transferase K00029 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.40 0.0 1151.0
TLS3_k127_3938507_1 Acetyl-coenzyme A synthetase N-terminus K01895,K01908 - 6.2.1.1,6.2.1.17 1.894e-319 988.0
TLS3_k127_3938507_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001778 257.0
TLS3_k127_3938507_3 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000009984 184.0
TLS3_k127_3938507_4 COG3306 Glycosyltransferase involved in LPS biosynthesis K07270 - - 0.00000000000000000001378 101.0
TLS3_k127_3938507_5 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000003088 83.0
TLS3_k127_3952198_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 2.741e-226 708.0
TLS3_k127_3952198_1 Carboxylesterase family K01066,K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 384.0
TLS3_k127_3953519_0 ABC-type sugar transport system periplasmic component K02027,K10227 - - 1.877e-233 728.0
TLS3_k127_3953519_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 424.0
TLS3_k127_3961053_0 glucose sorbosone - - - 2.789e-208 654.0
TLS3_k127_3961053_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 443.0
TLS3_k127_3961053_10 Tetratricopeptide repeat - - - 0.00000006738 65.0
TLS3_k127_3961053_11 AAA ATPase domain - - - 0.0000005356 55.0
TLS3_k127_3961053_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 376.0
TLS3_k127_3961053_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000005576 208.0
TLS3_k127_3961053_4 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000002597 199.0
TLS3_k127_3961053_5 COG3591 V8-like Glu-specific endopeptidase K04775 - - 0.000000000000000000000000000001079 132.0
TLS3_k127_3961053_6 PFAM Cytochrome c, class I - - - 0.000000000000000000000000001047 115.0
TLS3_k127_3961053_7 Tetratricopeptide repeat - - - 0.0000000000000000003403 96.0
TLS3_k127_3961053_8 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000006451 90.0
TLS3_k127_3961053_9 Transcriptional regulatory protein, C terminal - - - 0.0000000001456 70.0
TLS3_k127_3968080_0 DNA polymerase alpha chain like domain K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1516.0
TLS3_k127_3968080_1 COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 542.0
TLS3_k127_3968080_2 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K13482 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 373.0
TLS3_k127_3968080_3 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000000000352 160.0
TLS3_k127_3968080_4 Subtilase family - - - 0.0000000000000000000000001359 114.0
TLS3_k127_3983954_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 555.0
TLS3_k127_3983954_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 451.0
TLS3_k127_3983954_2 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000002452 151.0
TLS3_k127_3983954_3 Component of SufBCD complex - - - 0.0000000000000003448 83.0
TLS3_k127_3986700_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 2.263e-211 664.0
TLS3_k127_3986700_1 Domain of unknown function DUF21 K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 417.0
TLS3_k127_3986700_2 PFAM helix-turn-helix- domain containing protein AraC type K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 328.0
TLS3_k127_3986700_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000005831 229.0
TLS3_k127_4008115_0 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000009042 238.0
TLS3_k127_4008115_1 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000007138 190.0
TLS3_k127_4008115_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000009747 188.0
TLS3_k127_4008115_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000002681 175.0
TLS3_k127_4008115_4 Chorismate mutase type II K04092 - 5.4.99.5 0.0000000000000000000000000000000000000003349 161.0
TLS3_k127_4008115_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000004778 136.0
TLS3_k127_4008115_6 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000002557 51.0
TLS3_k127_4025300_0 P-type ATPase' K01533 - 3.6.3.4 2.277e-219 700.0
TLS3_k127_4025300_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 312.0
TLS3_k127_4025300_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 299.0
TLS3_k127_4025300_3 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000007825 250.0
TLS3_k127_4025300_4 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.0000000000000000000000000000000000000006776 158.0
TLS3_k127_4025300_5 Protein of unknown function (DUF1467) - - - 0.00000000000000000001919 102.0
TLS3_k127_4025300_6 Cytochrome oxidase maturation protein - - - 0.000000000003861 80.0
TLS3_k127_4037918_0 Permease family K03458 - - 6.93e-236 741.0
TLS3_k127_4037918_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 516.0
TLS3_k127_4037918_2 Sodium calcium exchanger membrane K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 362.0
TLS3_k127_4037918_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002443 263.0
TLS3_k127_4037918_4 Iron-sulfur cluster-binding protein K04755 - - 0.0000000000000000000000000000000000000000000000000000000004899 204.0
TLS3_k127_4037918_5 DNA polymerase III K00960 - 2.7.7.6 0.000000000000000000000000000000000000000000203 165.0
TLS3_k127_4037918_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000005927 130.0
TLS3_k127_4037918_7 FR47-like protein - - - 0.0000000000000000000000000000001851 136.0
TLS3_k127_4046194_0 PFAM GGDEF domain containing protein K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 428.0
TLS3_k127_4046194_1 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000000000000000004722 166.0
TLS3_k127_4046194_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000006197 108.0
TLS3_k127_4070341_0 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 461.0
TLS3_k127_4070341_1 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000004591 224.0
TLS3_k127_4075554_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.824e-293 923.0
TLS3_k127_4075554_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000006871 244.0
TLS3_k127_4075554_2 COG0534 Na -driven multidrug efflux pump K03327 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000005303 142.0
TLS3_k127_4076014_0 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 605.0
TLS3_k127_4076014_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 470.0
TLS3_k127_4076014_2 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 432.0
TLS3_k127_4076014_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 351.0
TLS3_k127_4076014_4 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000005409 229.0
TLS3_k127_4102008_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.358e-203 640.0
TLS3_k127_4102008_1 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000002704 231.0
TLS3_k127_4102008_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000001431 224.0
TLS3_k127_4102008_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000005124 207.0
TLS3_k127_4102008_4 Sugar-specific transcriptional regulator TrmB K03892 - - 0.00000000000000000000000000000000000000000000007855 170.0
TLS3_k127_4102008_5 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000000000000003967 179.0
TLS3_k127_4102008_6 KR domain - - - 0.000000000000000000000000000001967 129.0
TLS3_k127_4106759_0 Male sterility protein K12454 - 5.1.3.10 9.555e-277 884.0
TLS3_k127_4106759_1 Radical SAM domain protein - - - 3.562e-215 674.0
TLS3_k127_4106759_2 epimerase dehydratase K01784,K08678,K12454,K17947 - 4.1.1.35,5.1.3.10,5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 464.0
TLS3_k127_4106759_3 Glycosyl transferase 4-like domain - - - 0.0000000003744 61.0
TLS3_k127_4108751_0 Putative nucleotidyltransferase substrate binding domain K02342,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 585.0
TLS3_k127_4108751_1 Lysin motif - - - 0.000008332 52.0
TLS3_k127_4112315_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 8.663e-224 701.0
TLS3_k127_4112315_1 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005619 282.0
TLS3_k127_4112315_2 pdz dhr glgf - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009633 247.0
TLS3_k127_4112315_3 Phasin protein - - - 0.00000000006812 68.0
TLS3_k127_4123981_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 381.0
TLS3_k127_4123981_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 376.0
TLS3_k127_4123981_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000000001711 134.0
TLS3_k127_4123981_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000001543 76.0
TLS3_k127_4124634_0 GNAT family acetyltransferase K03802 - 6.3.2.29,6.3.2.30 0.0 1189.0
TLS3_k127_4124634_1 COG4242 Cyanophycinase and related exopeptidases K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 612.0
TLS3_k127_4124634_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000007594 119.0
TLS3_k127_4143015_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
TLS3_k127_4143015_1 Glycosyltransferase like family 2 - - - 0.0000000000001433 79.0
TLS3_k127_4143015_2 Sulfotransferase domain - - - 0.0000005016 63.0
TLS3_k127_4147579_0 Alpha-glucoside ABC transporter substrate-binding protein K10232 - - 5.949e-208 654.0
TLS3_k127_4147579_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038,K21977 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 556.0
TLS3_k127_4147579_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 365.0
TLS3_k127_4147579_11 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 361.0
TLS3_k127_4147579_12 DNA-binding response regulator K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 350.0
TLS3_k127_4147579_13 SIS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 349.0
TLS3_k127_4147579_14 flagellar hook-associated protein K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 310.0
TLS3_k127_4147579_15 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001913 250.0
TLS3_k127_4147579_16 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
TLS3_k127_4147579_17 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001052 228.0
TLS3_k127_4147579_18 Polysaccharide pyruvyl transferase K16563 - - 0.00000000000000000000000000000000000000000000000000000000000007158 237.0
TLS3_k127_4147579_19 mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000009494 186.0
TLS3_k127_4147579_2 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 498.0
TLS3_k127_4147579_20 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000001141 184.0
TLS3_k127_4147579_21 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000201 117.0
TLS3_k127_4147579_22 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.00000000000000000000559 109.0
TLS3_k127_4147579_23 - - - - 0.0000000000000003854 85.0
TLS3_k127_4147579_24 family 8 - - - 0.000000000007917 76.0
TLS3_k127_4147579_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 489.0
TLS3_k127_4147579_4 basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 458.0
TLS3_k127_4147579_5 2-dehydrogenase K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 450.0
TLS3_k127_4147579_6 peptidase K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 402.0
TLS3_k127_4147579_7 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 383.0
TLS3_k127_4147579_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 377.0
TLS3_k127_4147579_9 Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 377.0
TLS3_k127_4173070_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 381.0
TLS3_k127_4173070_1 PFAM MgtE intracellular - - - 0.0000000000000000000000689 107.0
TLS3_k127_4179187_0 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000002302 216.0
TLS3_k127_4179187_1 - - - - 0.0000000000000000000000000000000000000000000000000000132 198.0
TLS3_k127_4179187_2 - - - - 0.00000000000000000000000000000000000000494 151.0
TLS3_k127_4179187_3 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000007698 107.0
TLS3_k127_4197556_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 376.0
TLS3_k127_4197556_1 conserved small protein - - - 0.00000000000000002949 83.0
TLS3_k127_4197556_2 PEP-CTERM motif - - - 0.000000142 59.0
TLS3_k127_4197716_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.27e-221 693.0
TLS3_k127_4197716_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 316.0
TLS3_k127_4197716_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000004093 72.0
TLS3_k127_4234122_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 582.0
TLS3_k127_4234122_1 COG1024 Enoyl-CoA hydratase carnithine racemase K00020,K01692 - 1.1.1.31,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 406.0
TLS3_k127_4234122_2 Aldehyde dehydrogenase family K00140 GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 299.0
TLS3_k127_4234122_3 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001598 286.0
TLS3_k127_4234122_4 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000007976 239.0
TLS3_k127_4241543_0 'PFAM Alpha amylase, catalytic K00690,K05341 - 2.4.1.4,2.4.1.7 2.25e-309 966.0
TLS3_k127_4241543_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 394.0
TLS3_k127_4241543_2 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002094 283.0
TLS3_k127_4241543_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000002063 194.0
TLS3_k127_4241543_4 SnoaL-like domain - - - 0.000000000000000000000000000000001141 133.0
TLS3_k127_4241543_5 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000002332 61.0
TLS3_k127_4242465_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1017.0
TLS3_k127_4242465_1 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 400.0
TLS3_k127_4242465_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009203 231.0
TLS3_k127_4253751_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1345.0
TLS3_k127_4253751_1 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 421.0
TLS3_k127_4253751_2 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 387.0
TLS3_k127_4253751_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 328.0
TLS3_k127_4253751_4 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002002 259.0
TLS3_k127_4253751_5 FadR C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002348 259.0
TLS3_k127_4253751_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000002207 145.0
TLS3_k127_4259884_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 7.692e-282 871.0
TLS3_k127_4259884_1 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 463.0
TLS3_k127_4259884_2 acetolactate synthase K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 297.0
TLS3_k127_4259884_3 BioY family K03523 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002143 281.0
TLS3_k127_4259884_4 Succinoglycan biosynthesis protein K16563,K21154 - 2.5.1.98 0.000000000000000000000000000000000000000000000000000000000000000009767 237.0
TLS3_k127_4259884_5 Protein of unknown function (DUF1349) K09702 - - 0.00000000000000000000000000000000000000000000000000000001143 203.0
TLS3_k127_4259884_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000006706 199.0
TLS3_k127_4259884_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000769 162.0
TLS3_k127_4275690_0 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 451.0
TLS3_k127_4275690_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 349.0
TLS3_k127_4275690_2 Cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002142 287.0
TLS3_k127_4275690_3 membrane protein, hemolysin III homolog K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000002178 211.0
TLS3_k127_4275690_4 Protein of unknown function (DUF3303) - - - 0.000000000000000000000111 100.0
TLS3_k127_4275690_5 Hypoxia induced protein conserved region - - - 0.0000000000000003057 80.0
TLS3_k127_4275690_7 - - - - 0.0001442 49.0
TLS3_k127_4277827_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 5.598e-204 644.0
TLS3_k127_4277827_1 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000000000000005003 201.0
TLS3_k127_428227_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 1.149e-243 759.0
TLS3_k127_428227_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.052e-200 634.0
TLS3_k127_428227_2 Domain of unknown function (DUF4131) K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 502.0
TLS3_k127_428227_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 410.0
TLS3_k127_428227_4 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000004998 156.0
TLS3_k127_428227_5 Protein of unknown function DUF72 - - - 0.000000000000007432 77.0
TLS3_k127_4339209_0 COG1157 Flagellar biosynthesis type III secretory pathway ATPase K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 499.0
TLS3_k127_4339209_1 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000001983 63.0
TLS3_k127_4347390_0 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 447.0
TLS3_k127_4347390_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 380.0
TLS3_k127_4347390_2 PIN domain - - - 0.000000000000000000000000000000000000000000000006873 187.0
TLS3_k127_4384742_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 452.0
TLS3_k127_4384742_1 PFAM MgtE intracellular - - - 0.0000000000000000000000000000004436 129.0
TLS3_k127_4384742_2 belongs to the thioredoxin family - - - 0.0000000001384 74.0
TLS3_k127_4448402_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 533.0
TLS3_k127_4448402_1 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995,K11957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 396.0
TLS3_k127_4448402_2 Peptidase family M23 - - - 0.0000000000000000000001289 110.0
TLS3_k127_4461369_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.325e-239 746.0
TLS3_k127_4461369_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 553.0
TLS3_k127_4461369_2 ATPases associated with a variety of cellular activities K10191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 421.0
TLS3_k127_4461369_3 KR domain K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004255 273.0
TLS3_k127_447137_0 elongation factor G K02355 - - 8.16e-207 662.0
TLS3_k127_447137_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 456.0
TLS3_k127_447137_2 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 311.0
TLS3_k127_447137_3 - - - - 0.000000005624 61.0
TLS3_k127_4500224_0 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 618.0
TLS3_k127_4500224_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 447.0
TLS3_k127_4500224_2 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 363.0
TLS3_k127_4500224_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 328.0
TLS3_k127_4500224_4 HAMP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006957 293.0
TLS3_k127_4500224_5 Transcriptional regulatory protein, C terminal K02483,K07665,K07669 - - 0.00000000000000000000000000000000000000000000000000003269 196.0
TLS3_k127_4500224_6 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000001363 148.0
TLS3_k127_4500224_7 Phosphotransferase enzyme family - - - 0.00000000000000006198 90.0
TLS3_k127_4500224_8 Heavy-metal-associated domain K07213 - - 0.00000004351 60.0
TLS3_k127_4500224_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000257 50.0
TLS3_k127_4515077_0 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001662 284.0
TLS3_k127_4515077_1 Transposase and inactivated derivatives - - - 0.00000000000000000551 89.0
TLS3_k127_4515077_2 Flagellar protein FlgJ - - - 0.000000001043 59.0
TLS3_k127_4534358_0 catalyzes the oxidation of dihydrolipoamide to lipoamide K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 2.037e-223 700.0
TLS3_k127_4534358_1 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 1.202e-205 666.0
TLS3_k127_4534358_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000503 256.0
TLS3_k127_4534358_3 MAPEG family - - - 0.0000000000000000000000000000000000000000000000000001492 188.0
TLS3_k127_4534358_4 Domain of unknown function (DUF892) - - - 0.000000000000000000000000002273 121.0
TLS3_k127_4550831_0 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 3.812e-208 662.0
TLS3_k127_4550831_1 Putative sugar-binding N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 485.0
TLS3_k127_4550831_2 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 377.0
TLS3_k127_4550831_3 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 361.0
TLS3_k127_4551164_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 1.795e-212 683.0
TLS3_k127_4551164_1 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 576.0
TLS3_k127_4551164_2 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 348.0
TLS3_k127_4551164_3 - K03571 - - 0.00000000002968 76.0
TLS3_k127_4552088_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.201e-297 926.0
TLS3_k127_4552088_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 4.774e-195 619.0
TLS3_k127_4552088_2 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 572.0
TLS3_k127_4552088_3 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000000000009817 96.0
TLS3_k127_4559843_0 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 471.0
TLS3_k127_4559843_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 361.0
TLS3_k127_4580625_0 membrane-anchored protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 469.0
TLS3_k127_4580625_1 Protein conserved in bacteria K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 410.0
TLS3_k127_4580625_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001172 263.0
TLS3_k127_4609570_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 457.0
TLS3_k127_4609570_1 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001613 274.0
TLS3_k127_4615252_0 NADH ubiquinone oxidoreductase 17.2 kD subunit K00356 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000002725 202.0
TLS3_k127_4615252_1 PFAM Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000000000000000000000000008394 182.0
TLS3_k127_4615252_2 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000004021 159.0
TLS3_k127_4615252_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000004391 129.0
TLS3_k127_4615252_4 Protein conserved in bacteria - - - 0.000000000000000000000000007518 118.0
TLS3_k127_46265_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 595.0
TLS3_k127_46265_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 512.0
TLS3_k127_46265_2 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003293 286.0
TLS3_k127_46265_3 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000002013 241.0
TLS3_k127_46265_4 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000000001462 162.0
TLS3_k127_46265_5 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000001177 168.0
TLS3_k127_46265_6 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000003371 59.0
TLS3_k127_4646001_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1279.0
TLS3_k127_4646001_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 547.0
TLS3_k127_4646001_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 499.0
TLS3_k127_4646001_3 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 301.0
TLS3_k127_4646001_4 peptidyl-prolyl isomerase K01802,K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000002597 240.0
TLS3_k127_4646001_5 NUDIX domain K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000001977 226.0
TLS3_k127_4646001_6 Competence protein - - - 0.000000000000000000000000000000000000000000000000004003 188.0
TLS3_k127_4646001_7 Translation initiation factor 2 - - - 0.000003205 51.0
TLS3_k127_464811_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.321e-239 748.0
TLS3_k127_464811_1 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 1.243e-218 707.0
TLS3_k127_464811_10 secreted (Periplasmic) protein - - - 0.00000000000000001772 93.0
TLS3_k127_464811_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 398.0
TLS3_k127_464811_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 353.0
TLS3_k127_464811_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001513 304.0
TLS3_k127_464811_5 Ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000000002758 236.0
TLS3_k127_464811_6 COG3023 Negative regulator of beta-lactamase expression K00788,K01447,K03806,K11066 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000001689 216.0
TLS3_k127_464811_7 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000328 174.0
TLS3_k127_464811_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000001743 139.0
TLS3_k127_464811_9 - - - - 0.0000000000000000000006809 105.0
TLS3_k127_4648995_0 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 364.0
TLS3_k127_4648995_1 transcriptional regulator - - - 0.000000000000000000000000000000004768 133.0
TLS3_k127_4648995_2 - - - - 0.000000000000000000002327 101.0
TLS3_k127_4657590_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 576.0
TLS3_k127_4657590_1 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000003824 205.0
TLS3_k127_4657590_2 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 0.00000000000000002135 83.0
TLS3_k127_46642_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 419.0
TLS3_k127_46642_1 chaperone - - - 0.00000000000000000000000000000000000000000000000000000000000000002066 228.0
TLS3_k127_46642_2 MerR HTH family regulatory protein K18997 - - 0.000000000000004467 85.0
TLS3_k127_4669180_0 Pyridoxal-phosphate dependent enzyme K01754 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 415.0
TLS3_k127_4669180_1 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 384.0
TLS3_k127_4669180_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001703 305.0
TLS3_k127_4669180_3 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000004771 261.0
TLS3_k127_4669180_4 Belongs to the beta-ketoacyl-ACP synthases family K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 0.00000000000000004639 81.0
TLS3_k127_4681248_0 ABC-type multidrug transport system ATPase and permease K06147,K18893 - - 7.147e-270 843.0
TLS3_k127_4681248_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 397.0
TLS3_k127_4681248_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 428.0
TLS3_k127_4681248_3 - - - - 0.000000000000000000000000000000002514 135.0
TLS3_k127_4681248_4 Protein export membrane protein K03296 - - 0.0000000001566 66.0
TLS3_k127_4681248_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000114 62.0
TLS3_k127_470770_0 trimethylamine methyltransferase K14083 - 2.1.1.250 4.116e-221 691.0
TLS3_k127_470770_1 FAD binding domain K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 419.0
TLS3_k127_470770_2 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 365.0
TLS3_k127_470770_3 Transcriptional regulator, GntR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 300.0
TLS3_k127_470770_4 Pyrimidine 5'-nucleotidase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 295.0
TLS3_k127_4707858_0 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 528.0
TLS3_k127_4707858_1 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 413.0
TLS3_k127_4708214_0 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001506 265.0
TLS3_k127_4708214_1 PFAM Mo-dependent nitrogenase - - - 0.00000000000000000000000000000000000000000000000915 180.0
TLS3_k127_4708214_2 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000003897 118.0
TLS3_k127_4723394_0 RNA 2'-O ribose methyltransferase substrate binding K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 328.0
TLS3_k127_4723394_1 CoA-binding domain protein K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000002436 203.0
TLS3_k127_4723394_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000000001351 196.0
TLS3_k127_4723394_3 tRNA synthetases class I (K) K04566 - 6.1.1.6 0.000000000000000000000000000000000000000009189 156.0
TLS3_k127_4723394_4 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000006516 120.0
TLS3_k127_4723394_5 - - - - 0.0003683 45.0
TLS3_k127_4739864_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 606.0
TLS3_k127_4739864_1 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 443.0
TLS3_k127_4739864_2 Branched-chain amino acid transport system / permease component K10440 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000000006768 151.0
TLS3_k127_4739864_3 Calcium sodium antiporter activity. It is involved in the biological process described with cell communication K05849 GO:0000003,GO:0000302,GO:0001508,GO:0001666,GO:0001701,GO:0001890,GO:0001892,GO:0002026,GO:0002027,GO:0002028,GO:0002244,GO:0002376,GO:0002520,GO:0003006,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003018,GO:0003674,GO:0005215,GO:0005432,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005783,GO:0005789,GO:0005856,GO:0005874,GO:0005886,GO:0005887,GO:0005901,GO:0005911,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006816,GO:0006851,GO:0006873,GO:0006874,GO:0006875,GO:0006883,GO:0006936,GO:0006937,GO:0006939,GO:0006941,GO:0006942,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007204,GO:0007272,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007584,GO:0007602,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0008015,GO:0008016,GO:0008092,GO:0008150,GO:0008324,GO:0008366,GO:0009314,GO:0009410,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009605,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009743,GO:0009746,GO:0009749,GO:0009790,GO:0009791,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0009991,GO:0010001,GO:0010033,GO:0010035,GO:0010243,GO:0010522,GO:0010644,GO:0010646,GO:0010647,GO:0010649,GO:0010762,GO:0010763,GO:0010880,GO:0010881,GO:0010882,GO:0010959,GO:0012505,GO:0014070,GO:0014074,GO:0014704,GO:0014706,GO:0014819,GO:0014829,GO:0015075,GO:0015077,GO:0015081,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015318,GO:0015368,GO:0015491,GO:0015630,GO:0015672,GO:0016020,GO:0016021,GO:0016323,GO:0019722,GO:0019725,GO:0019867,GO:0019932,GO:0021537,GO:0022008,GO:0022414,GO:0022804,GO:0022857,GO:0022890,GO:0023051,GO:0023052,GO:0023056,GO:0030001,GO:0030003,GO:0030004,GO:0030016,GO:0030017,GO:0030018,GO:0030054,GO:0030097,GO:0030154,GO:0030278,GO:0030315,GO:0030334,GO:0030335,GO:0030425,GO:0030500,GO:0030501,GO:0030506,GO:0030900,GO:0031000,GO:0031090,GO:0031224,GO:0031226,GO:0031594,GO:0031667,GO:0031674,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0031984,GO:0032501,GO:0032502,GO:0032879,GO:0033198,GO:0033273,GO:0033280,GO:0033554,GO:0033993,GO:0034220,GO:0034284,GO:0034599,GO:0034614,GO:0034762,GO:0034765,GO:0034976,GO:0035050,GO:0035051,GO:0035150,GO:0035295,GO:0035296,GO:0035556,GO:0035637,GO:0035690,GO:0035725,GO:0035902,GO:0035994,GO:0036270,GO:0036293,GO:0036294,GO:0036376,GO:0036477,GO:0040012,GO:0040017,GO:0042063,GO:0042175,GO:0042221,GO:0042310,GO:0042383,GO:0042391,GO:0042493,GO:0042542,GO:0042552,GO:0042592,GO:0042692,GO:0042995,GO:0043005,GO:0043009,GO:0043025,GO:0043167,GO:0043169,GO:0043197,GO:0043198,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043269,GO:0043279,GO:0043292,GO:0044057,GO:0044291,GO:0044297,GO:0044309,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044430,GO:0044432,GO:0044444,GO:0044446,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044557,GO:0044853,GO:0045121,GO:0045202,GO:0045211,GO:0045778,GO:0046677,GO:0046683,GO:0046872,GO:0046873,GO:0048167,GO:0048168,GO:0048172,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048568,GO:0048608,GO:0048709,GO:0048731,GO:0048738,GO:0048747,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050804,GO:0050806,GO:0050877,GO:0050880,GO:0050884,GO:0050890,GO:0050896,GO:0050905,GO:0051049,GO:0051094,GO:0051146,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051272,GO:0051279,GO:0051282,GO:0051480,GO:0051481,GO:0051560,GO:0051591,GO:0051606,GO:0051641,GO:0051649,GO:0051716,GO:0051899,GO:0051924,GO:0055001,GO:0055002,GO:0055006,GO:0055007,GO:0055013,GO:0055065,GO:0055067,GO:0055074,GO:0055078,GO:0055080,GO:0055082,GO:0055085,GO:0055117,GO:0055119,GO:0060047,GO:0060048,GO:0060078,GO:0060291,GO:0060322,GO:0060341,GO:0060401,GO:0060402,GO:0060429,GO:0060537,GO:0061061,GO:0061337,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0070167,GO:0070169,GO:0070482,GO:0070509,GO:0070588,GO:0070838,GO:0070887,GO:0071310,GO:0071312,GO:0071313,GO:0071320,GO:0071407,GO:0071415,GO:0071417,GO:0071453,GO:0071456,GO:0071466,GO:0071495,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0086001,GO:0086010,GO:0086012,GO:0086036,GO:0086038,GO:0086064,GO:0086065,GO:0090066,GO:0090075,GO:0090257,GO:0097060,GO:0097447,GO:0097458,GO:0097553,GO:0097746,GO:0097756,GO:0098588,GO:0098589,GO:0098590,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098703,GO:0098719,GO:0098735,GO:0098739,GO:0098771,GO:0098794,GO:0098805,GO:0098827,GO:0098857,GO:0099080,GO:0099081,GO:0099177,GO:0099512,GO:0099513,GO:0099516,GO:0099580,GO:0099587,GO:0120025,GO:0120038,GO:0140115,GO:1901660,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902656,GO:1903169,GO:1903522,GO:1903779,GO:1904062,GO:1990034,GO:2000026,GO:2000145,GO:2000147 - 0.00001073 53.0
TLS3_k127_4740825_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1204.0
TLS3_k127_4740825_1 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 1.716e-314 967.0
TLS3_k127_4740825_2 surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 606.0
TLS3_k127_4740825_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 441.0
TLS3_k127_4740825_4 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 426.0
TLS3_k127_4740825_5 methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001241 248.0
TLS3_k127_4740825_6 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000005248 181.0
TLS3_k127_4740825_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000001251 132.0
TLS3_k127_4744011_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 377.0
TLS3_k127_4744011_1 - - - - 0.000000000000000000000000000000000000000000000000000007116 203.0
TLS3_k127_4744011_2 Biotin/lipoate A/B protein ligase family - - - 0.000000000000000000000000000000000000000000004172 168.0
TLS3_k127_4744011_3 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000002523 146.0
TLS3_k127_4744011_4 Protein of unknown function (DUF3306) - - - 0.0000000000000000000000003758 117.0
TLS3_k127_4767570_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.634e-317 977.0
TLS3_k127_4767570_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 592.0
TLS3_k127_4767570_2 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 552.0
TLS3_k127_4767570_3 deiminase K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 524.0
TLS3_k127_4767570_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 438.0
TLS3_k127_4767570_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000002212 176.0
TLS3_k127_4772450_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.389e-261 818.0
TLS3_k127_4772450_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 529.0
TLS3_k127_4772450_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 487.0
TLS3_k127_4772450_3 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 486.0
TLS3_k127_4772450_4 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 397.0
TLS3_k127_4772450_5 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000007231 168.0
TLS3_k127_4787862_0 Cys/Met metabolism PLP-dependent enzyme K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 3.463e-230 751.0
TLS3_k127_4787862_1 Cyclic nucleotide-monophosphate binding domain K00384 - 1.8.1.9 1.034e-205 661.0
TLS3_k127_4787862_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 312.0
TLS3_k127_4787862_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001135 218.0
TLS3_k127_4787862_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000001373 60.0
TLS3_k127_4787862_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000001737 61.0
TLS3_k127_4790127_0 TIGRFAM aminopeptidase N K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 1.008e-318 995.0
TLS3_k127_4790127_1 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 358.0
TLS3_k127_4808242_0 Proton-conducting membrane transporter K05568 - - 3.273e-201 662.0
TLS3_k127_4808242_1 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 520.0
TLS3_k127_4808242_2 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000002958 211.0
TLS3_k127_4808242_3 PFAM NADH-ubiquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000004224 124.0
TLS3_k127_4808242_4 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.0000000000000000000000000005844 115.0
TLS3_k127_4812529_0 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 402.0
TLS3_k127_4812529_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 368.0
TLS3_k127_4812529_2 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 357.0
TLS3_k127_4812529_3 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 360.0
TLS3_k127_4812529_4 transcriptional regulator, lysr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 350.0
TLS3_k127_4812529_5 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 297.0
TLS3_k127_4812529_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001121 274.0
TLS3_k127_4818580_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 557.0
TLS3_k127_4819260_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.363e-204 644.0
TLS3_k127_4819260_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 541.0
TLS3_k127_4819260_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000002368 158.0
TLS3_k127_4884509_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1613.0
TLS3_k127_4884509_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122 - 1.17.1.9 4.513e-293 909.0
TLS3_k127_4884509_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 475.0
TLS3_k127_4884509_3 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 468.0
TLS3_k127_4884509_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 451.0
TLS3_k127_4884509_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 421.0
TLS3_k127_4884509_6 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 310.0
TLS3_k127_4884509_7 Resolvase - - - 0.00000005602 57.0
TLS3_k127_4897723_0 PFAM Xanthine uracil vitamin C permease K03458,K16345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 376.0
TLS3_k127_4897723_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 387.0
TLS3_k127_4897723_10 - K16915 - - 0.00000000000002243 78.0
TLS3_k127_4897723_11 PFAM Nickel uptake substrate-specific transmembrane region - - - 0.0000365 55.0
TLS3_k127_4897723_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 368.0
TLS3_k127_4897723_3 Domain of unknown function (DUF4198) K02009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 349.0
TLS3_k127_4897723_4 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001717 284.0
TLS3_k127_4897723_5 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002336 286.0
TLS3_k127_4897723_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000001682 214.0
TLS3_k127_4897723_7 Transcriptional activator HlyU - - - 0.0000000000000000000001913 100.0
TLS3_k127_4897723_8 - - - - 0.000000000000000008368 96.0
TLS3_k127_4897723_9 - K16915 - - 0.000000000000000008485 92.0
TLS3_k127_4922985_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 1.282e-252 788.0
TLS3_k127_4922985_1 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 427.0
TLS3_k127_4922985_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 306.0
TLS3_k127_4922985_3 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000001004 221.0
TLS3_k127_4922985_4 ubiE/COQ5 methyltransferase family - - - 0.00000000599 60.0
TLS3_k127_4946329_0 MotA TolQ ExbB proton channel K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 340.0
TLS3_k127_4946329_1 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000005274 207.0
TLS3_k127_4946329_2 thioesterase K07107 - - 0.000000000000000000000000000000000004209 141.0
TLS3_k127_4946329_3 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0000000000000000000000000000484 117.0
TLS3_k127_4946329_4 Membrane - - - 0.000003435 55.0
TLS3_k127_4957064_0 Melibiase K07407 - 3.2.1.22 5.55e-278 876.0
TLS3_k127_4957064_1 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 587.0
TLS3_k127_4957064_2 Resolvase - - - 0.000003657 55.0
TLS3_k127_4964761_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 7.144e-237 740.0
TLS3_k127_4964761_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 529.0
TLS3_k127_4964761_10 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000002101 192.0
TLS3_k127_4964761_11 Virulence factor - - - 0.00000000000000000000000000000000000009597 149.0
TLS3_k127_4964761_2 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 445.0
TLS3_k127_4964761_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 443.0
TLS3_k127_4964761_4 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 364.0
TLS3_k127_4964761_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 335.0
TLS3_k127_4964761_6 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 336.0
TLS3_k127_4964761_7 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 330.0
TLS3_k127_4964761_8 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006512 257.0
TLS3_k127_4964761_9 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000669 197.0
TLS3_k127_4972255_0 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 489.0
TLS3_k127_4972255_1 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 349.0
TLS3_k127_4972255_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 332.0
TLS3_k127_4974598_0 MotA TolQ ExbB proton channel K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 329.0
TLS3_k127_4974598_1 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000004446 189.0
TLS3_k127_4974598_2 thioesterase' K07107 - - 0.00000000000000000000000000000000000000001708 158.0
TLS3_k127_4980723_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 1.845e-217 685.0
TLS3_k127_4980723_1 Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 542.0
TLS3_k127_4980723_2 Domain of unknown function (DUF1802) - - - 0.0000006247 53.0
TLS3_k127_4988416_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 1.978e-221 714.0
TLS3_k127_4988416_1 AbgT putative transporter family K12942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
TLS3_k127_4988416_2 DinB family - - - 0.0000000000000000000000000000000000000000000000008709 180.0
TLS3_k127_4988416_3 Including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000004057 152.0
TLS3_k127_5001349_0 Single-stranded-DNA-specific exonuclease (RecJ) K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 1.183e-210 677.0
TLS3_k127_5001349_1 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002426 262.0
TLS3_k127_5001349_2 in Escherichia coli this protein forms a dimer and binds manganese K02446,K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000002433 144.0
TLS3_k127_5001349_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000009228 80.0
TLS3_k127_5013061_0 COG0524 Sugar kinases, ribokinase family K00847,K00856 - 2.7.1.20,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 387.0
TLS3_k127_5013061_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 333.0
TLS3_k127_5013061_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000001904 124.0
TLS3_k127_5013061_3 PFAM Rickettsia 17 kDa surface antigen - - - 0.00001442 49.0
TLS3_k127_5030622_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497,K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 439.0
TLS3_k127_5030622_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 336.0
TLS3_k127_5030622_2 FCD - - - 0.00000000000000000000000000000000000000000000000009015 185.0
TLS3_k127_5030622_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000239 179.0
TLS3_k127_5032461_0 Sulfite reductase K00381 - 1.8.1.2 3.085e-271 847.0
TLS3_k127_5032461_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 561.0
TLS3_k127_5032461_10 Protein of unknown function (DUF2849) - - - 0.00000000000000000121 93.0
TLS3_k127_5032461_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 516.0
TLS3_k127_5032461_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046116,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072531,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1990397 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 297.0
TLS3_k127_5032461_4 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003298 270.0
TLS3_k127_5032461_5 transcriptional regulator K05800 - - 0.000000000000000000000000000000000000000000000000000000000000000001658 231.0
TLS3_k127_5032461_6 - - - - 0.0000000000000000000000000000000000000000000000002121 191.0
TLS3_k127_5032461_7 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000001446 165.0
TLS3_k127_5032461_8 protein conserved in bacteria K17218 - 1.8.5.4 0.00000000000000000000000000003124 128.0
TLS3_k127_5032461_9 Bacterial protein of unknown function (DUF934) - - - 0.000000000000000000000000003205 124.0
TLS3_k127_5034188_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.803e-263 820.0
TLS3_k127_5034188_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006221 258.0
TLS3_k127_5034188_2 HPr Serine kinase C-terminal domain K06023 - - 0.0000000000000000000000000000000001045 139.0
TLS3_k127_5034188_3 3-hydroxyacyl-coa dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000053 100.0
TLS3_k127_5049530_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.35e-232 730.0
TLS3_k127_5049530_1 RNA polymerase, sigma 32 subunit, RpoH K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 402.0
TLS3_k127_5049530_2 Iron-regulated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009023 267.0
TLS3_k127_5049530_3 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000004349 216.0
TLS3_k127_5070337_0 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 283.0
TLS3_k127_5070337_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005226 289.0
TLS3_k127_5070337_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008956 242.0
TLS3_k127_5101426_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 423.0
TLS3_k127_5115274_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1058.0
TLS3_k127_5115274_1 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 529.0
TLS3_k127_5115274_2 Polyphosphate kinase 2 (PPK2) K22468 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 522.0
TLS3_k127_5115274_3 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 429.0
TLS3_k127_5115274_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002282 271.0
TLS3_k127_5115274_5 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000008936 246.0
TLS3_k127_5115274_6 Domain of unknown function (DUF3576) - - - 0.00000000000000000000000000000009755 132.0
TLS3_k127_5115274_7 Gram-negative porin K08720 - - 0.00000000000000000001082 104.0
TLS3_k127_5115274_8 Gram-negative porin K08720 - - 0.00000003004 65.0
TLS3_k127_5141007_0 rpsU-divergently transcribed protein K18587 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003777 256.0
TLS3_k127_5141007_1 GrpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003667 224.0
TLS3_k127_5141007_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000004783 114.0
TLS3_k127_5141007_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000001651 112.0
TLS3_k127_5142105_0 MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 397.0
TLS3_k127_5142105_1 Dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000001182 225.0
TLS3_k127_5142105_2 NfeD-like C-terminal, partner-binding K07340 - - 0.0008517 51.0
TLS3_k127_5153575_0 Heat shock 70 kDa protein K04043 - - 0.0 1033.0
TLS3_k127_5153575_1 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 443.0
TLS3_k127_5153575_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000001318 110.0
TLS3_k127_5153575_2 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 401.0
TLS3_k127_5153575_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 375.0
TLS3_k127_5153575_4 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 312.0
TLS3_k127_5153575_5 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007855 288.0
TLS3_k127_5153575_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001926 263.0
TLS3_k127_5153575_7 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000002647 186.0
TLS3_k127_5153575_8 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000009191 162.0
TLS3_k127_5153575_9 Bacterial SH3 domain - - - 0.0000000000000000000000000001854 125.0
TLS3_k127_5166230_0 COG0471 Di- and tricarboxylate transporters - - - 7.365e-226 715.0
TLS3_k127_5166230_1 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 607.0
TLS3_k127_5166230_2 YmdB-like protein K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 409.0
TLS3_k127_5166230_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 404.0
TLS3_k127_5166230_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003525 268.0
TLS3_k127_5166230_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000006103 159.0
TLS3_k127_5174631_0 Phage capsid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 591.0
TLS3_k127_5174631_1 Terminase RNaseH-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 576.0
TLS3_k127_5174631_2 Phage portal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 540.0
TLS3_k127_5174631_3 Caudovirus prohead serine protease K06904 - - 0.000000000000000000000000000000000000000000000000000000000001684 218.0
TLS3_k127_5174631_4 - - - - 0.00000000000000003107 93.0
TLS3_k127_5181030_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 522.0
TLS3_k127_5181030_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 317.0
TLS3_k127_5181030_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000004776 171.0
TLS3_k127_5206411_0 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 396.0
TLS3_k127_5206411_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 308.0
TLS3_k127_5206411_2 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 310.0
TLS3_k127_5206411_3 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004178 251.0
TLS3_k127_5206411_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003832 244.0
TLS3_k127_5206411_5 Branched-chain amino acid transport system / permease component K10440 - - 0.0000001892 52.0
TLS3_k127_5211697_0 DNA topoisomerase K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 461.0
TLS3_k127_5211697_1 stress protein (general stress protein 26) - - - 0.000000000000000000000000000000000000000000000000000000000000003454 226.0
TLS3_k127_5211697_2 - - - - 0.000000000000009605 77.0
TLS3_k127_5233157_0 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 471.0
TLS3_k127_5233157_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 297.0
TLS3_k127_5233157_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001532 267.0
TLS3_k127_5233157_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000126 259.0
TLS3_k127_5233157_4 Membrane - - - 0.0000000000000000000001568 111.0
TLS3_k127_5272467_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.69e-204 649.0
TLS3_k127_5272467_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 511.0
TLS3_k127_5272467_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 439.0
TLS3_k127_5272467_3 COG0330 Membrane protease subunits stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 432.0
TLS3_k127_5272467_4 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 325.0
TLS3_k127_5272467_5 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 289.0
TLS3_k127_5272467_6 Protein of unknown function (DUF983) - - - 0.0000000000000008044 78.0
TLS3_k127_5272467_7 COG1585 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000000000001657 79.0
TLS3_k127_5272467_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000008112 78.0
TLS3_k127_5288249_0 Belongs to the GcvT family K00315 - 1.5.8.4 0.0 1379.0
TLS3_k127_5288249_1 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 305.0
TLS3_k127_5288249_2 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000001854 130.0
TLS3_k127_5301223_0 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
TLS3_k127_5301223_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002545 295.0
TLS3_k127_5301223_2 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000003579 200.0
TLS3_k127_5301223_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000001508 173.0
TLS3_k127_5301223_4 invasion associated locus B - - - 0.0000000000000000000000000000000000000000001229 165.0
TLS3_k127_5301223_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000002091 142.0
TLS3_k127_5301223_6 - - - - 0.0000000000001541 78.0
TLS3_k127_5301223_7 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00003046 49.0
TLS3_k127_5320554_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1471.0
TLS3_k127_5320554_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1043.0
TLS3_k127_5320554_2 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 433.0
TLS3_k127_5320554_3 soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000000000000005041 220.0
TLS3_k127_5320554_4 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000308 188.0
TLS3_k127_5320554_5 Flavodoxin-like fold - - - 0.0000000000000000009785 96.0
TLS3_k127_5320554_7 PFAM Adenosine AMP deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000749 76.0
TLS3_k127_5325447_0 Domain of unknown function (DUF4339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 528.0
TLS3_k127_5325447_1 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 419.0
TLS3_k127_5325447_2 Protein of unknown function (DUF2927) - - - 0.0000000000000000000000000000000000004254 143.0
TLS3_k127_5339556_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 9.791e-212 672.0
TLS3_k127_5339556_1 NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 460.0
TLS3_k127_5339556_2 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000004963 156.0
TLS3_k127_5352801_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 294.0
TLS3_k127_5352801_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000004783 162.0
TLS3_k127_5352801_2 signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000001246 155.0
TLS3_k127_5363991_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 462.0
TLS3_k127_5363991_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 417.0
TLS3_k127_5363991_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 389.0
TLS3_k127_5363991_3 EamA-like transporter family K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 325.0
TLS3_k127_5363991_4 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 308.0
TLS3_k127_5363991_5 xylanase chitin deacetylase - - - 0.00001164 54.0
TLS3_k127_5422041_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 471.0
TLS3_k127_5422041_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007569 270.0
TLS3_k127_5422041_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000147 172.0
TLS3_k127_5422041_3 transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000000000148 152.0
TLS3_k127_544752_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000004342 243.0
TLS3_k127_544752_1 Protein of unknown function (DUF3140) - - - 0.0000000000000000000000000000000000000000007169 162.0
TLS3_k127_544752_2 Lipoprotein - - - 0.0000000000000000000004606 108.0
TLS3_k127_5457541_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 6.191e-227 711.0
TLS3_k127_5457541_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 293.0
TLS3_k127_5457541_2 COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis K02502 - - 0.00000000000000000000000000000000000000005306 156.0
TLS3_k127_5463994_0 Belongs to the GPI family K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 8.561e-213 684.0
TLS3_k127_5463994_1 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 301.0
TLS3_k127_5463994_2 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000002029 232.0
TLS3_k127_5463994_3 Belongs to the IlvD Edd family K01690 - 4.2.1.12 0.00000000000000000000000000000003561 126.0
TLS3_k127_5463994_4 Universal stress protein family - - - 0.00000000000000000000000206 114.0
TLS3_k127_5463994_5 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000007625 51.0
TLS3_k127_5471794_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1165.0
TLS3_k127_5471794_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 7.434e-207 649.0
TLS3_k127_5471794_2 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 490.0
TLS3_k127_5471794_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 467.0
TLS3_k127_5471794_4 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 405.0
TLS3_k127_5471794_5 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 359.0
TLS3_k127_5471794_6 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 340.0
TLS3_k127_5471794_7 glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000002482 252.0
TLS3_k127_5471794_8 Protein of unknown function (DUF1489) - - - 0.0000000000000000000000000000000000000001124 174.0
TLS3_k127_5471794_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000002401 127.0
TLS3_k127_5478202_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 8.161e-254 803.0
TLS3_k127_5478202_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid K00130 - 1.2.1.8 2.047e-200 632.0
TLS3_k127_5478202_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 307.0
TLS3_k127_5527134_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 290.0
TLS3_k127_5527134_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 291.0
TLS3_k127_5527134_2 methyltransferase - - - 0.0000000000000000000000000000002953 130.0
TLS3_k127_5527575_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 462.0
TLS3_k127_5527575_1 Short-chain dehydrogenase reductase sdr K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 351.0
TLS3_k127_5527575_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000006039 243.0
TLS3_k127_5527693_0 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000001561 168.0
TLS3_k127_5527693_1 Histidine kinase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000004485 86.0
TLS3_k127_5530469_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 445.0
TLS3_k127_5530469_1 Glycine cleavage system T protein K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 376.0
TLS3_k127_5530469_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 369.0
TLS3_k127_5530469_3 Type I phosphodiesterase / nucleotide pyrophosphatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007135 295.0
TLS3_k127_5530469_4 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000001365 198.0
TLS3_k127_5530469_5 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000004323 162.0
TLS3_k127_5552494_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0 1013.0
TLS3_k127_5552494_1 alpha-ribazole phosphatase activity - - - 0.00000000000000000000000000000000006428 145.0
TLS3_k127_5552494_2 Scp-like extracellular - - - 0.00000000000000000000000000000001066 139.0
TLS3_k127_5552494_3 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000001879 129.0
TLS3_k127_5552494_4 PEP-CTERM motif - - - 0.00000000000000000000004487 108.0
TLS3_k127_5564645_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.137e-271 859.0
TLS3_k127_5564645_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000006725 172.0
TLS3_k127_5594543_0 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 443.0
TLS3_k127_5594543_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 360.0
TLS3_k127_5594543_2 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001873 253.0
TLS3_k127_5594543_3 DNA ligase K01971 - 6.5.1.1 0.000002525 49.0
TLS3_k127_5609190_0 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 450.0
TLS3_k127_5609190_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 348.0
TLS3_k127_5609190_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000002743 221.0
TLS3_k127_5609190_3 Indole-3-glycerol phosphate synthase K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000000000000000000000000007984 113.0
TLS3_k127_5616271_0 ABC-type multidrug transport system ATPase and permease K06147,K18893 - - 6.649e-231 730.0
TLS3_k127_5616271_1 ABC-type multidrug transport system ATPase and permease K06147,K18893 - - 0.00000000000000000000000000000000000000000000000000001872 189.0
TLS3_k127_5625362_0 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 428.0
TLS3_k127_5625362_1 Penicillin-binding protein 5, C-terminal domain K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 362.0
TLS3_k127_5625362_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 328.0
TLS3_k127_5625362_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
TLS3_k127_5625362_4 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000006884 164.0
TLS3_k127_5625362_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000007232 125.0
TLS3_k127_5625362_6 NUDIX domain - - - 0.00000000000005085 72.0
TLS3_k127_5630579_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 353.0
TLS3_k127_5630579_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000001542 195.0
TLS3_k127_5630579_2 peptidase K02278 - 3.4.23.43 0.000000000004482 77.0
TLS3_k127_5630579_4 type II secretion system protein K12511 - - 0.0000007588 51.0
TLS3_k127_5630913_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 409.0
TLS3_k127_5630913_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 310.0
TLS3_k127_5630913_2 cytochrome P450 K00493 - 1.14.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 302.0
TLS3_k127_5649371_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 553.0
TLS3_k127_5649371_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000004637 162.0
TLS3_k127_5681343_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.092e-291 901.0
TLS3_k127_5681343_1 anion transporter K14445 - - 1.032e-264 834.0
TLS3_k127_5681343_10 COG3187 Heat shock protein - - - 0.00000000000000000003285 96.0
TLS3_k127_5681343_2 Acyl-CoA dehydrogenase type 2 domain K14448 - 1.3.8.12 6.351e-243 762.0
TLS3_k127_5681343_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 482.0
TLS3_k127_5681343_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 384.0
TLS3_k127_5681343_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 336.0
TLS3_k127_5681343_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004634 256.0
TLS3_k127_5681343_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000503 262.0
TLS3_k127_5681343_8 Protein of unknown function (DUF1491) - - - 0.000000000000000000000000000000000000000000001689 174.0
TLS3_k127_5682482_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 452.0
TLS3_k127_5682482_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000265 201.0
TLS3_k127_5682482_2 Sulfotransferase family - - - 0.0000000000000000000000000007478 124.0
TLS3_k127_5686429_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 451.0
TLS3_k127_5686429_1 GcrA cell cycle regulator K13583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002131 249.0
TLS3_k127_5686429_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000003071 198.0
TLS3_k127_5686429_3 Aminotransferase K00813,K00832 - 2.6.1.1,2.6.1.57 0.00000000000004256 73.0
TLS3_k127_5686834_0 Conserved hypothetical protein 2217 (DUF2460) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 302.0
TLS3_k127_5686834_1 Phage conserved hypothetical protein BR0599 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 308.0
TLS3_k127_5686834_2 COG5281, Phage-related minor tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000000321 226.0
TLS3_k127_5686834_3 Major tail protein, TP901-1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000009828 221.0
TLS3_k127_5686834_4 Phage tail tube protein, GTA-gp10 - - - 0.00000000000000000000000000001411 127.0
TLS3_k127_5686834_5 Head-tail adaptor - - - 0.0000000000000000000000000002129 119.0
TLS3_k127_5686834_6 gene transfer agent protein - - - 0.000000000000000000000004775 111.0
TLS3_k127_5686834_7 Phage tail assembly chaperone protein, TAC - - - 0.00000000008467 70.0
TLS3_k127_5686834_8 - - - - 0.000000002313 58.0
TLS3_k127_5692875_0 TIGRFAM nitrogen regulation protein NR(I) K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 395.0
TLS3_k127_5692875_1 PFAM ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 381.0
TLS3_k127_5692875_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 329.0
TLS3_k127_5692875_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000004377 231.0
TLS3_k127_5692875_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000001046 121.0
TLS3_k127_5728840_0 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 491.0
TLS3_k127_5728840_1 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 374.0
TLS3_k127_5728840_2 Domain of unknown function (DUF427) - - - 0.00000000000000000000001383 102.0
TLS3_k127_5728840_3 Protein of unknown function (DUF1214) - - - 0.0000002234 52.0
TLS3_k127_5729671_0 phosphate regulon transcriptional regulatory protein PhoB K07657,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 343.0
TLS3_k127_5729671_1 PFAM ATP-binding region ATPase domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 309.0
TLS3_k127_5729671_2 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000001577 241.0
TLS3_k127_5729671_3 Transcriptional regulator, LuxR family hydrolase, alpha beta fold family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004955 241.0
TLS3_k127_5729671_4 GcrA cell cycle regulator K13583 - - 0.000000000000000000000000000000000000000002544 157.0
TLS3_k127_5740558_0 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 284.0
TLS3_k127_5740558_1 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000001862 162.0
TLS3_k127_5745103_0 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 543.0
TLS3_k127_5745103_1 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K10126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 532.0
TLS3_k127_5745103_2 COG0583 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 339.0
TLS3_k127_5745103_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 284.0
TLS3_k127_5748859_0 ABC transporter K17204 - - 0.0 1041.0
TLS3_k127_5748859_1 C-terminal domain of alpha-glycerophosphate oxidase K00111,K21054 - 1.1.1.402,1.1.5.3 1.589e-253 803.0
TLS3_k127_5748859_2 FGGY family of carbohydrate kinases, N-terminal domain K00862 - 2.7.1.215 3.361e-223 706.0
TLS3_k127_5748859_3 Xylose isomerase domain protein TIM barrel K21909 - 5.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 547.0
TLS3_k127_5748859_4 Branched-chain amino acid transport system / permease component K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 529.0
TLS3_k127_5748859_5 Putative sugar-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 419.0
TLS3_k127_5748859_6 COG1178 ABC-type Fe3 transport system permease component K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002553 287.0
TLS3_k127_5748859_7 Predicted periplasmic lipoprotein (DUF2291) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001243 246.0
TLS3_k127_5752923_0 GMC oxidoreductase K19813 - 1.1.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 485.0
TLS3_k127_5752923_1 Involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002125 283.0
TLS3_k127_5752923_2 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000786 178.0
TLS3_k127_5752923_3 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000001169 159.0
TLS3_k127_5805675_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 311.0
TLS3_k127_5805675_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000162 201.0
TLS3_k127_5805675_2 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000001635 121.0
TLS3_k127_5805675_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000007265 86.0
TLS3_k127_5805675_4 recombinase activity - - - 0.000009884 51.0
TLS3_k127_5817750_0 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 317.0
TLS3_k127_5817750_1 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 311.0
TLS3_k127_5817750_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004869 258.0
TLS3_k127_5817750_3 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002786 233.0
TLS3_k127_5817750_4 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000003365 102.0
TLS3_k127_5817750_5 - - - - 0.0000000000000001354 83.0
TLS3_k127_5821733_0 Mannitol dehydrogenase Rossmann domain K00040,K00045 - 1.1.1.57,1.1.1.67 7.957e-216 689.0
TLS3_k127_5821733_1 ABC transporter K10111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 560.0
TLS3_k127_5821733_2 ABC-type sugar transport systems, permease components K10228 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 499.0
TLS3_k127_5821733_3 ABC-type sugar transport system, permease component K10229 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 479.0
TLS3_k127_5821733_4 TIGRFAM FGGY-family pentulose kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 419.0
TLS3_k127_5821733_5 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000003209 223.0
TLS3_k127_5821733_6 -acetyltransferase - - - 0.0000000000000000000000000303 126.0
TLS3_k127_5823681_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 371.0
TLS3_k127_5823681_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000008417 183.0
TLS3_k127_5823681_2 SnoaL-like domain - - - 0.0000000000000000000000000000007185 127.0
TLS3_k127_5836283_0 3-beta hydroxysteroid dehydrogenase isomerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 412.0
TLS3_k127_5836283_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 GO:0008150,GO:0042221,GO:0046677,GO:0050896 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 342.0
TLS3_k127_5836283_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 317.0
TLS3_k127_5836283_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000005611 111.0
TLS3_k127_5837836_0 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 372.0
TLS3_k127_5837836_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003173 276.0
TLS3_k127_5837836_2 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002167 237.0
TLS3_k127_5837836_3 Cytochrome c oxidase caa3-type, assembly factor K02351 - - 0.000000000000000000000000000000000000000000000000000000000000000007529 235.0
TLS3_k127_5837836_4 Uncharacterised protein family (UPF0093) - - - 0.0000000000000000000000000000008397 141.0
TLS3_k127_5837836_5 FAD binding domain - - - 0.000000000000000003234 97.0
TLS3_k127_5854576_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0 1009.0
TLS3_k127_5854576_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 336.0
TLS3_k127_5854576_2 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 330.0
TLS3_k127_5854576_3 Protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000000000000000000000001434 197.0
TLS3_k127_5854576_4 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000000000000000008748 189.0
TLS3_k127_5854576_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000000000000003651 181.0
TLS3_k127_5887248_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.845e-202 636.0
TLS3_k127_5887248_1 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000008348 269.0
TLS3_k127_5887248_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000001659 110.0
TLS3_k127_5904677_0 ABC transporter K10441 - 3.6.3.17 1.268e-224 711.0
TLS3_k127_5904677_1 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 504.0
TLS3_k127_5904677_2 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 471.0
TLS3_k127_5904677_3 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 443.0
TLS3_k127_5904677_4 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007189 260.0
TLS3_k127_5904677_5 L-rhamnose mutarotase K03534 - 5.1.3.32 0.00000000000000000000000000000000000000009251 166.0
TLS3_k127_5904677_6 - - - - 0.00000000000000000000000000000136 125.0
TLS3_k127_592394_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.046e-302 932.0
TLS3_k127_592394_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 3.453e-209 659.0
TLS3_k127_592394_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000005308 235.0
TLS3_k127_592394_3 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000004941 159.0
TLS3_k127_592394_4 Peptidase family S49 K04773 - - 0.00006325 49.0
TLS3_k127_5948051_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 406.0
TLS3_k127_5948051_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K21134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002994 280.0
TLS3_k127_5948051_2 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002226 267.0
TLS3_k127_5948051_3 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002323 253.0
TLS3_k127_5955077_0 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 454.0
TLS3_k127_5955077_1 Creatinase/Prolidase N-terminal domain K01271,K15783 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.4.13.9,3.5.4.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 356.0
TLS3_k127_5963412_0 Cys/Met metabolism PLP-dependent enzyme K00643 - 2.3.1.37 1.228e-202 651.0
TLS3_k127_5963412_1 PUCC protein K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 595.0
TLS3_k127_5963412_11 bacterioferritin-associated ferredoxin - - - 0.00000000000000000000000005606 109.0
TLS3_k127_5963412_2 STAS domain K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 584.0
TLS3_k127_5963412_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K04035 - 1.14.13.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 578.0
TLS3_k127_5963412_4 Photosynthetic reaction centre, H-chain N-terminal region K13991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009579,GO:0016020,GO:0034357,GO:0042716,GO:0042717,GO:0044424,GO:0044436,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 302.0
TLS3_k127_5963412_5 Photosynthetic complex assembly protein 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 304.0
TLS3_k127_5963412_6 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000006142 258.0
TLS3_k127_5963412_7 Magnesium-protoporphyrin IX methyltransferase C-terminus K03428 - 2.1.1.11 0.00000000000000000000000000000000000000000000000000000000001998 210.0
TLS3_k127_5963412_8 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000001679 198.0
TLS3_k127_5963412_9 - - - - 0.00000000000000000000000000000000000000000325 172.0
TLS3_k127_5970435_0 Cobalamin biosynthesis protein CobT K09883 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 503.0
TLS3_k127_5970435_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000005101 209.0
TLS3_k127_5970435_2 DnaK suppressor protein - - - 0.00000000000000000000000000001558 122.0
TLS3_k127_6010466_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 386.0
TLS3_k127_6010466_1 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 287.0
TLS3_k127_6010466_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002757 273.0
TLS3_k127_6010466_3 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000000000000000000000000001162 187.0
TLS3_k127_6010466_4 Glycine zipper 2TM domain K06077 - - 0.00003167 49.0
TLS3_k127_6025003_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 567.0
TLS3_k127_6025003_1 TIGRFAM Penicillin-binding protein 1C K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 457.0
TLS3_k127_6027713_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 507.0
TLS3_k127_6027713_1 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 411.0
TLS3_k127_6027713_2 ABC-type sugar transport system periplasmic component K10552 - - 0.000000009354 59.0
TLS3_k127_6033164_0 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 591.0
TLS3_k127_6033164_1 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 352.0
TLS3_k127_6033164_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 362.0
TLS3_k127_6033164_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 310.0
TLS3_k127_6033164_4 Animal haem peroxidase - - - 0.00000000000000000000000000000000000000000000009111 192.0
TLS3_k127_6033164_5 Transcriptional - - - 0.0000000000000000000000000000000000000000000003407 181.0
TLS3_k127_6045584_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 533.0
TLS3_k127_6045584_1 Sigma-54 interaction domain K10912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 531.0
TLS3_k127_6045584_2 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006964 287.0
TLS3_k127_6045584_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000002586 244.0
TLS3_k127_6045584_4 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000005824 170.0
TLS3_k127_6045584_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000331 132.0
TLS3_k127_6045584_6 His Kinase A (phosphoacceptor) domain K07678,K20974 - 2.7.13.3 0.0000000000000000000001114 113.0
TLS3_k127_6046234_0 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 389.0
TLS3_k127_6046234_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 350.0
TLS3_k127_6046234_2 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 308.0
TLS3_k127_6046234_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000008827 259.0
TLS3_k127_6046234_4 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000003276 79.0
TLS3_k127_6048206_0 Peptidase dimerisation domain K01436 - - 1.318e-216 680.0
TLS3_k127_6048206_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 599.0
TLS3_k127_6048206_2 Glycosyl hydrolase catalytic core - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 417.0
TLS3_k127_6048206_3 TrkA-C domain - - - 0.00000000000000000000000000000000000000000000001696 172.0
TLS3_k127_606960_0 Participates in both transcription termination and antitermination K02600 - - 8.659e-248 789.0
TLS3_k127_606960_1 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 292.0
TLS3_k127_606960_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000001079 253.0
TLS3_k127_606960_3 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.00000000000000000000000000000000000000000000000000000000007269 216.0
TLS3_k127_606960_4 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000002749 90.0
TLS3_k127_6078377_0 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 455.0
TLS3_k127_6078377_1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 353.0
TLS3_k127_6078377_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 329.0
TLS3_k127_6078377_3 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 311.0
TLS3_k127_6078377_4 - - - - 0.00000000009771 70.0
TLS3_k127_6089680_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 519.0
TLS3_k127_6089680_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 357.0
TLS3_k127_6089680_2 Cytochrome c1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 345.0
TLS3_k127_6089680_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 316.0
TLS3_k127_6089680_4 PFAM Maf family protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000003665 220.0
TLS3_k127_6089680_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000009485 222.0
TLS3_k127_6089680_6 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000179 203.0
TLS3_k127_6115430_0 Esterase-like activity of phytase K01077 - 3.1.3.1 2.736e-294 921.0
TLS3_k127_6115430_1 DnaJ C terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 345.0
TLS3_k127_6115430_2 MerR HTH family regulatory protein K18997 - - 0.0000000000000002453 83.0
TLS3_k127_6131293_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 454.0
TLS3_k127_6131293_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 404.0
TLS3_k127_6131293_2 ABC transporter K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 377.0
TLS3_k127_6131293_3 ABC transporter K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 337.0
TLS3_k127_6131293_4 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K18608 GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.30 0.000000000000000000000000000000000000869 152.0
TLS3_k127_613220_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 469.0
TLS3_k127_613220_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001138 256.0
TLS3_k127_6160056_0 Alpha-amylase domain K01187 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.20 4.233e-248 781.0
TLS3_k127_6160056_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 366.0
TLS3_k127_6160056_2 gluconolactonase activity K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000009067 239.0
TLS3_k127_6160056_3 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000001099 168.0
TLS3_k127_6160056_4 GcrA cell cycle regulator K13583 - - 0.000000000000000002733 85.0
TLS3_k127_6178415_0 Protein of unknown function (DUF3485) - - - 9.733e-195 621.0
TLS3_k127_6178415_1 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 594.0
TLS3_k127_6178415_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 525.0
TLS3_k127_6178415_3 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 379.0
TLS3_k127_6178415_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000009602 216.0
TLS3_k127_6178415_5 Protein conserved in bacteria - - - 0.00000000000000000006741 103.0
TLS3_k127_6218772_0 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 451.0
TLS3_k127_6218772_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 407.0
TLS3_k127_6218772_2 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 384.0
TLS3_k127_622754_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 567.0
TLS3_k127_622754_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 441.0
TLS3_k127_622754_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 309.0
TLS3_k127_6247564_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 280.0
TLS3_k127_6247564_1 methyltransferase - - - 0.0000000000000000000000000000000000000000001423 168.0
TLS3_k127_6247564_2 SpoIIAA-like - - - 0.00000000000000000005422 98.0
TLS3_k127_6247564_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000001033 93.0
TLS3_k127_6259756_0 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 363.0
TLS3_k127_6259756_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000002309 124.0
TLS3_k127_6259756_2 Exopolysaccharide biosynthesis protein YbjH - - - 0.0000000000009653 72.0
TLS3_k127_6259756_3 COG0457 FOG TPR repeat - - - 0.00000002174 64.0
TLS3_k127_6260870_0 Sarcosine oxidase, alpha subunit family K00302 - 1.5.3.1 5.45e-275 857.0
TLS3_k127_6260870_1 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 377.0
TLS3_k127_6260870_2 COG2186 Transcriptional regulators K19775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002023 267.0
TLS3_k127_6260870_3 COG4583 Sarcosine oxidase gamma subunit K00305 - 1.5.3.1 0.0000000000000000000000000000000000000009895 156.0
TLS3_k127_6266610_0 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 363.0
TLS3_k127_6266610_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 296.0
TLS3_k127_6266610_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000108 126.0
TLS3_k127_6266610_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000006362 68.0
TLS3_k127_6270127_0 including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 451.0
TLS3_k127_6270127_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000598 254.0
TLS3_k127_6270127_2 nuclear chromosome segregation - - - 0.00000000000000000000000002473 115.0
TLS3_k127_6273950_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 437.0
TLS3_k127_6273950_1 Major facilitator superfamily K08223 - - 0.000000000000000000000000000004873 126.0
TLS3_k127_6273950_2 Transporter, major facilitator family protein K08223 - - 0.00000000003912 70.0
TLS3_k127_6273950_3 - - - - 0.00000001691 63.0
TLS3_k127_6273950_4 Major facilitator superfamily K08223 - - 0.00000004378 56.0
TLS3_k127_6289120_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 492.0
TLS3_k127_6289120_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 448.0
TLS3_k127_6289120_2 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 411.0
TLS3_k127_6289120_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 349.0
TLS3_k127_6349434_0 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000005736 227.0
TLS3_k127_6349434_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000001617 216.0
TLS3_k127_638513_0 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 316.0
TLS3_k127_638513_1 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000028 65.0
TLS3_k127_6397441_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 1.996e-274 853.0
TLS3_k127_6397441_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 332.0
TLS3_k127_6397441_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001383 258.0
TLS3_k127_6397441_3 Amb_all - - - 0.0000000000000000000000000000000000008297 148.0
TLS3_k127_6412385_0 mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 590.0
TLS3_k127_6412385_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 517.0
TLS3_k127_6412385_2 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 357.0
TLS3_k127_6413237_0 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002824 275.0
TLS3_k127_6413237_1 response to pH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005508 259.0
TLS3_k127_6413237_2 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000001086 209.0
TLS3_k127_6413237_3 Protein of unknown function (DUF861) - - - 0.0000000000000000000000000008242 116.0
TLS3_k127_6419083_0 Helicase associated domain (HA2) Add an annotation K03579 - 3.6.4.13 1.171e-198 630.0
TLS3_k127_6419083_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000007427 210.0
TLS3_k127_6442431_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 434.0
TLS3_k127_6442431_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000001613 222.0
TLS3_k127_6442733_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 346.0
TLS3_k127_6442733_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 299.0
TLS3_k127_6442733_2 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000006625 175.0
TLS3_k127_6443372_0 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 615.0
TLS3_k127_6443372_1 ABC-type transport system, periplasmic component surface lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 502.0
TLS3_k127_6443372_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 505.0
TLS3_k127_6443372_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 483.0
TLS3_k127_6443372_4 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 341.0
TLS3_k127_6443372_5 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 309.0
TLS3_k127_6443372_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000004898 78.0
TLS3_k127_6443372_7 - - - - 0.000000002051 71.0
TLS3_k127_644815_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 511.0
TLS3_k127_644815_1 Belongs to the HpcH HpaI aldolase family K08691 GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 496.0
TLS3_k127_644815_2 Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 469.0
TLS3_k127_644815_3 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 297.0
TLS3_k127_644815_4 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 275.0
TLS3_k127_644815_5 cell division protein K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001078 264.0
TLS3_k127_644815_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000215 224.0
TLS3_k127_644815_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.00000000000000000000000000000000000000000000000000000000001619 229.0
TLS3_k127_645097_0 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 346.0
TLS3_k127_645097_1 Flavoprotein involved in K transport K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 342.0
TLS3_k127_645097_2 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007742 255.0
TLS3_k127_645097_3 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006353 239.0
TLS3_k127_645097_4 Belongs to the glycosyl hydrolase 68 family K00692,K01193 GO:0005575,GO:0005576 2.4.1.10,3.2.1.26 0.0000000000000000000000000001428 118.0
TLS3_k127_6456155_0 COG0433 Predicted ATPase K06915 - - 1.702e-204 647.0
TLS3_k127_6456155_1 short chain dehydrogenase - - - 0.0000000000003125 73.0
TLS3_k127_6460478_0 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 324.0
TLS3_k127_6460478_1 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001609 221.0
TLS3_k127_6460478_2 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002779 77.0
TLS3_k127_6461534_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 3.163e-218 681.0
TLS3_k127_6461534_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000001416 231.0
TLS3_k127_6461534_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000002071 146.0
TLS3_k127_6483145_0 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 424.0
TLS3_k127_6483145_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 GO:0003674,GO:0003824,GO:0005488,GO:0006040,GO:0006044,GO:0006046,GO:0006054,GO:0006082,GO:0008150,GO:0008152,GO:0008270,GO:0008448,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0016999,GO:0017001,GO:0017144,GO:0019213,GO:0019262,GO:0019752,GO:0022607,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046348,GO:0046395,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 418.0
TLS3_k127_6484639_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 503.0
TLS3_k127_6484639_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 471.0
TLS3_k127_6484639_2 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 361.0
TLS3_k127_6484639_3 16S RNA G1207 methylase RsmC K00564 - 2.1.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000006873 258.0
TLS3_k127_6484639_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000000003428 182.0
TLS3_k127_6484639_5 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins - - - 0.00000000000000000000001069 104.0
TLS3_k127_6484639_6 Phasin protein - - - 0.00000000001785 71.0
TLS3_k127_6491380_0 Histidine kinase K13587 - 2.7.13.3 5.532e-202 653.0
TLS3_k127_6491380_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 576.0
TLS3_k127_6491380_2 esterase K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003863 279.0
TLS3_k127_6504113_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 505.0
TLS3_k127_6504113_1 Aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 452.0
TLS3_k127_6504113_2 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005375 248.0
TLS3_k127_6504113_3 glucose sorbosone K00117,K21430 - 1.1.5.2 0.00000000000000000000000000000000000000005041 153.0
TLS3_k127_6509709_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.393e-226 709.0
TLS3_k127_6509709_1 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 527.0
TLS3_k127_6509709_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 420.0
TLS3_k127_6509709_3 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 402.0
TLS3_k127_6516403_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 393.0
TLS3_k127_6516403_1 PFAM fumarylacetoacetate (FAA) hydrolase K16165 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0008948,GO:0016787,GO:0016822,GO:0016823,GO:0016829,GO:0016830,GO:0016831,GO:0018773,GO:0031974,GO:0031981,GO:0034545,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 348.0
TLS3_k127_6516403_2 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000008877 178.0
TLS3_k127_6516403_3 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497,K14652 - 3.5.4.25,4.1.99.12 0.000000002481 65.0
TLS3_k127_6516403_4 Flagellar hook-length control protein FliK K02414,K10565 - - 0.000000002614 65.0
TLS3_k127_6523238_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 415.0
TLS3_k127_6523238_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002786 245.0
TLS3_k127_6523238_2 ChrR Cupin-like domain K07167 - - 0.000000000000000000000001041 109.0
TLS3_k127_6523238_3 Protein conserved in bacteria - - - 0.00000000000000000000002479 111.0
TLS3_k127_6544267_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 8.624e-203 640.0
TLS3_k127_6544267_1 translation release factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 391.0
TLS3_k127_6544267_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 393.0
TLS3_k127_6544267_3 Alkyl hydroperoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000007616 207.0
TLS3_k127_6544267_4 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000001012 154.0
TLS3_k127_6544267_5 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000004439 66.0
TLS3_k127_6563531_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1515.0
TLS3_k127_6621940_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 347.0
TLS3_k127_6621940_1 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 306.0
TLS3_k127_6621940_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007854 287.0
TLS3_k127_6621940_3 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000003485 123.0
TLS3_k127_6621940_4 SnoaL-like domain - - - 0.00000003602 65.0
TLS3_k127_6629217_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 477.0
TLS3_k127_6629217_1 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009042 238.0
TLS3_k127_6658880_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 3.691e-224 707.0
TLS3_k127_6658880_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 609.0
TLS3_k127_6658880_10 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000247 135.0
TLS3_k127_6658880_11 AAA domain K02282 - - 0.00000000000006245 77.0
TLS3_k127_6658880_12 TadE-like protein - - - 0.00002915 54.0
TLS3_k127_6658880_2 Transporter associated domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 585.0
TLS3_k127_6658880_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 427.0
TLS3_k127_6658880_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 407.0
TLS3_k127_6658880_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 329.0
TLS3_k127_6658880_6 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 312.0
TLS3_k127_6658880_7 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 306.0
TLS3_k127_6658880_8 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000002287 148.0
TLS3_k127_6658880_9 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000001988 146.0
TLS3_k127_6679406_0 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
TLS3_k127_6679406_1 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000000004809 224.0
TLS3_k127_6679406_2 (Lipo)protein K04754 - - 0.0000000000000000000000000000000000000000000000000000001084 205.0
TLS3_k127_6679406_3 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000003516 142.0
TLS3_k127_6679406_4 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000003097 118.0
TLS3_k127_6682791_0 - - - - 0.00000000000000000155 92.0
TLS3_k127_6682791_1 PhoP regulatory network protein YrbL - - - 0.00000000000000007664 89.0
TLS3_k127_6703353_0 lipoprotein releasing system, transmembrane protein, LolC E family' K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 527.0
TLS3_k127_6703353_1 SAF K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 312.0
TLS3_k127_6703353_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 290.0
TLS3_k127_6703353_3 Response regulator receiver - - - 0.0000000000000002878 83.0
TLS3_k127_6722395_0 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 1.018e-208 662.0
TLS3_k127_6722395_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 535.0
TLS3_k127_6722395_2 Dak1 domain K05878 - 2.7.1.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 418.0
TLS3_k127_6722395_3 WD domain, G-beta repeat K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 392.0
TLS3_k127_6722395_4 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009339 256.0
TLS3_k127_6722395_5 - - - - 0.00000000000000000000003298 108.0
TLS3_k127_6722395_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000002307 75.0
TLS3_k127_6739225_0 COG3524 Capsule polysaccharide export protein K10107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 310.0
TLS3_k127_6739225_1 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005656 272.0
TLS3_k127_6739225_2 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005909 259.0
TLS3_k127_6739225_3 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000002023 217.0
TLS3_k127_6739225_4 - - - - 0.00000000000000000000000000000000008865 148.0
TLS3_k127_6745050_0 Acetyl-CoA dehydrogenase C-terminal like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 508.0
TLS3_k127_6745050_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 338.0
TLS3_k127_6745050_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005703 245.0
TLS3_k127_6747063_0 Domain of unknown function (DUF4445) - - - 0.0 1004.0
TLS3_k127_6747063_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 3.193e-219 693.0
TLS3_k127_6747063_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 387.0
TLS3_k127_6747063_3 COG0526 Thiol-disulfide isomerase and thioredoxins K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000776 198.0
TLS3_k127_6747063_4 energy transducer activity K03832 - - 0.0000009651 52.0
TLS3_k127_6747063_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0001665 53.0
TLS3_k127_6769467_0 Belongs to the 5'-nucleotidase family K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 592.0
TLS3_k127_6769467_1 Aminotransferase class-III K16871 - 2.6.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 540.0
TLS3_k127_6769467_2 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 401.0
TLS3_k127_6769467_3 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000006027 235.0
TLS3_k127_6769467_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000003561 76.0
TLS3_k127_6769467_5 Belongs to the 'phage' integrase family - - - 0.0000000000752 68.0
TLS3_k127_6769467_6 - - - - 0.0004688 46.0
TLS3_k127_678590_0 ABC-type dipeptide transport system periplasmic component K02035 - - 2.547e-254 794.0
TLS3_k127_678590_1 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 483.0
TLS3_k127_678590_2 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 382.0
TLS3_k127_678590_3 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000838 247.0
TLS3_k127_678590_4 hydratase decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000006173 224.0
TLS3_k127_678590_5 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000002012 107.0
TLS3_k127_678590_6 - - - - 0.000001831 55.0
TLS3_k127_6804952_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 524.0
TLS3_k127_6804952_1 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000000000000001365 222.0
TLS3_k127_6804952_2 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000155 219.0
TLS3_k127_6804952_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000004721 111.0
TLS3_k127_6804952_4 Belongs to the UPF0235 family K09131 - - 0.000000000000000008473 93.0
TLS3_k127_6804952_5 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000739 78.0
TLS3_k127_6810144_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 351.0
TLS3_k127_6810144_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000001464 173.0
TLS3_k127_6819817_0 catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 4.826e-209 656.0
TLS3_k127_6819817_1 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 289.0
TLS3_k127_6819817_2 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000000000000009133 184.0
TLS3_k127_6819817_3 Enoyl-(Acyl carrier protein) reductase K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000006065 139.0
TLS3_k127_6855034_0 helicase superfamily c-terminal domain K17675 - 3.6.4.13 3.53e-307 957.0
TLS3_k127_6856091_0 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 538.0
TLS3_k127_6856091_1 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000005042 116.0
TLS3_k127_6856091_2 Stress-induced bacterial acidophilic repeat motif K06884 - - 0.00000000000000000000000005438 111.0
TLS3_k127_6879862_0 Transporter associated domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 330.0
TLS3_k127_6879862_1 Staphylococcal nuclease homologue - - - 0.00000000000003296 79.0
TLS3_k127_6910836_0 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K14447 - 5.4.99.63 0.0 1018.0
TLS3_k127_6910836_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K14446 - 1.1.1.1,1.3.1.85 0.000000000000000000000000000000000000000000001576 167.0
TLS3_k127_6910836_2 acid phosphatase activity - - - 0.00000000000000000000404 108.0
TLS3_k127_69509_0 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 455.0
TLS3_k127_69509_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000001497 191.0
TLS3_k127_69509_2 Methyltransferase domain K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000004688 187.0
TLS3_k127_69509_3 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000007551 122.0
TLS3_k127_69509_4 NADPH-dependent FMN reductase - - - 0.000000000000000000000002078 106.0
TLS3_k127_69509_5 Putative prokaryotic signal transducing protein - - - 0.0000000000000000001691 102.0
TLS3_k127_695403_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 443.0
TLS3_k127_695403_1 AraC-binding-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 332.0
TLS3_k127_695403_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000006595 107.0
TLS3_k127_695403_3 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 - 3.5.2.14 0.00000000000000000265 83.0
TLS3_k127_6966620_0 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 453.0
TLS3_k127_6966620_1 Gamma-glutamylputrescine oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 458.0
TLS3_k127_6966620_2 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 427.0
TLS3_k127_6966620_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 325.0
TLS3_k127_6966620_4 FAD dependent oxidoreductase K09471 - - 0.000000000262 65.0
TLS3_k127_6973680_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.163e-219 691.0
TLS3_k127_6973680_1 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 615.0
TLS3_k127_6973680_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000001509 80.0
TLS3_k127_6973680_11 Cytochrome C oxidase assembly protein - - - 0.0000000000003057 72.0
TLS3_k127_6973680_2 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 530.0
TLS3_k127_6973680_3 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 535.0
TLS3_k127_6973680_4 heme copper-type cytochrome quinol oxidase, subunit 3 K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 466.0
TLS3_k127_6973680_5 GCN5 family K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000007763 263.0
TLS3_k127_6973680_6 Surf1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000007541 222.0
TLS3_k127_6973680_7 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000005378 205.0
TLS3_k127_6973680_8 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000001085 91.0
TLS3_k127_6973680_9 - - - - 0.00000000000000005126 87.0
TLS3_k127_6975686_0 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases K03403 - 6.6.1.1 0.0 1547.0
TLS3_k127_6975686_1 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04039 - 1.3.7.7 4.029e-244 784.0
TLS3_k127_6975686_2 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 2.968e-213 678.0
TLS3_k127_6975686_3 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP K04037 - 1.3.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 534.0
TLS3_k127_6975686_4 2-vinyl bacteriochlorophyllide hydratase (BCHF) K11336 GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.165 0.0000000000000000000000000000000000000000000000000000000001055 208.0
TLS3_k127_6975686_5 Magnesium-protoporphyrin IX methyltransferase C-terminus K03428 GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.11 0.00000000000000000002097 96.0
TLS3_k127_6985143_0 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 313.0
TLS3_k127_6985143_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007336 284.0
TLS3_k127_6985143_2 carbon monoxide dehydrogenase K09386 - - 0.00000000000000000000000000000000000000000000000000000000001198 221.0
TLS3_k127_6985143_3 Disulfide bond formation protein DsbB K03611 - - 0.000000000000000000000000000000000000000000006527 177.0
TLS3_k127_6985143_4 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000002969 146.0
TLS3_k127_6985143_5 domain, Protein - - - 0.00000000000000000000000002553 119.0
TLS3_k127_6985143_7 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000002177 88.0
TLS3_k127_6985143_8 - - - - 0.00000000000000004717 89.0
TLS3_k127_6985143_9 Putative neutral zinc metallopeptidase K07054 - - 0.00002683 55.0
TLS3_k127_700737_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 3.379e-237 761.0
TLS3_k127_700737_1 polysaccharide deacetylase K01452 - 3.5.1.41 1.038e-220 707.0
TLS3_k127_700737_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 440.0
TLS3_k127_700737_3 PFAM amidohydrolase K18456 - 3.5.4.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 385.0
TLS3_k127_700737_4 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000000000000002764 177.0
TLS3_k127_7016991_0 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004914 286.0
TLS3_k127_7016991_1 Catalase K07217 - - 0.000000000000000000000000000000000000000005114 157.0
TLS3_k127_7016991_2 Catalase K07217 - - 0.00000000000000000000000000000000000000005607 154.0
TLS3_k127_7016991_3 FAD binding domain - - - 0.000000000000007556 78.0
TLS3_k127_7016991_4 PFAM Manganese containing catalase K07217 - - 0.0000004108 57.0
TLS3_k127_7018358_0 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 346.0
TLS3_k127_7018358_1 PTS system fructose IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000005586 180.0
TLS3_k127_7018358_2 WHG domain - - - 0.00000000000000000000000000000000000000001146 157.0
TLS3_k127_7018358_3 phosphocarrier, HPr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - 0.00000000000000000000000000000001275 128.0
TLS3_k127_7019632_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 512.0
TLS3_k127_7019632_1 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 359.0
TLS3_k127_7019632_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 349.0
TLS3_k127_7019632_3 Sulfite exporter TauE/SafE K07090 - - 0.00000004085 55.0
TLS3_k127_7033569_0 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 569.0
TLS3_k127_7033569_1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 475.0
TLS3_k127_7033569_2 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 413.0
TLS3_k127_7033569_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000002228 225.0
TLS3_k127_7033569_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000003082 228.0
TLS3_k127_7033569_5 nitrogen regulatory protein PII - - - 0.000000000000000000000000000000000000000000009743 164.0
TLS3_k127_7033569_6 - - - - 0.00004968 51.0
TLS3_k127_705998_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 8.058e-251 793.0
TLS3_k127_705998_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.207e-245 772.0
TLS3_k127_705998_10 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000009235 247.0
TLS3_k127_705998_11 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000001373 228.0
TLS3_k127_705998_12 COG2771 DNA-binding HTH domain-containing proteins K07782,K19731 - - 0.000000000000000000000000000000000006238 147.0
TLS3_k127_705998_13 Thioesterase K18700 - 3.1.2.29 0.000000000000000000000000001205 119.0
TLS3_k127_705998_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 552.0
TLS3_k127_705998_3 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 546.0
TLS3_k127_705998_4 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 509.0
TLS3_k127_705998_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 447.0
TLS3_k127_705998_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 302.0
TLS3_k127_705998_7 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005956 273.0
TLS3_k127_705998_8 Pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
TLS3_k127_705998_9 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000001597 246.0
TLS3_k127_7074260_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 601.0
TLS3_k127_7074260_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 524.0
TLS3_k127_7074260_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 471.0
TLS3_k127_7074260_3 Acetyltransferase, gnat family - - - 0.000000000000000000000000000000000000000001448 163.0
TLS3_k127_7074260_4 Ribosomal L27 protein K02899 - - 0.0000000000000000000000000000000000001121 141.0
TLS3_k127_7081900_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 444.0
TLS3_k127_7081900_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 409.0
TLS3_k127_7081900_2 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 328.0
TLS3_k127_7081900_3 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 308.0
TLS3_k127_7081900_4 Cytochrome c class I K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 311.0
TLS3_k127_7081900_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000003991 223.0
TLS3_k127_7081900_6 - - - - 0.000000002779 62.0
TLS3_k127_7101210_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 477.0
TLS3_k127_7101210_1 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 400.0
TLS3_k127_7101210_2 COG0768 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000002902 127.0
TLS3_k127_7104757_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 581.0
TLS3_k127_7104757_1 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000001372 146.0
TLS3_k127_7104757_2 COG1062 Zn-dependent alcohol dehydrogenases, class III K00153 - 1.1.1.306 0.0000000009356 60.0
TLS3_k127_7111920_0 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.0 1176.0
TLS3_k127_7111920_1 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 2.483e-315 978.0
TLS3_k127_7111920_10 sterol carrier protein - - - 0.00000000000000000000000000000000004041 141.0
TLS3_k127_7111920_11 S4 RNA-binding domain K04762 - - 0.000000000000000000000001426 108.0
TLS3_k127_7111920_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 1.04e-209 656.0
TLS3_k127_7111920_3 KR domain K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 399.0
TLS3_k127_7111920_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 384.0
TLS3_k127_7111920_5 inositol mono-phosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 316.0
TLS3_k127_7111920_6 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 302.0
TLS3_k127_7111920_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000001535 196.0
TLS3_k127_7111920_8 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000006413 193.0
TLS3_k127_7111920_9 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000001381 186.0
TLS3_k127_7113932_0 PFAM extracellular solute-binding protein family 1 K10117 - - 1.534e-225 708.0
TLS3_k127_7113932_1 ABC-type sugar transport systems permease components K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005251 267.0
TLS3_k127_7113932_2 SIS domain K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000006522 231.0
TLS3_k127_7113932_3 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000001352 180.0
TLS3_k127_7135003_0 hydrolase family 65, central catalytic K01194,K01838,K04844,K05342 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944 2.4.1.64,3.2.1.28,5.4.2.6 6.24e-306 961.0
TLS3_k127_7135003_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 394.0
TLS3_k127_7135003_2 PFAM Manganese containing catalase K07217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 427.0
TLS3_k127_7135003_3 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000001277 58.0
TLS3_k127_7147855_0 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 574.0
TLS3_k127_7147855_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008179 275.0
TLS3_k127_7149409_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1277.0
TLS3_k127_7149409_1 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 417.0
TLS3_k127_7149409_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 382.0
TLS3_k127_7149409_3 AefR-like transcriptional repressor, C-terminal region - - - 0.000000000000000000000000000000000000000000947 165.0
TLS3_k127_7149409_4 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000004707 135.0
TLS3_k127_7149409_5 Cold shock K03704 - - 0.000000000000000000000000006167 110.0
TLS3_k127_7149409_6 Domain of unknown function (DUF1330) - - - 0.000000000000000000000001326 106.0
TLS3_k127_7187807_0 ATPase family associated with various cellular activities (AAA) K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 461.0
TLS3_k127_7187807_1 SAF K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 328.0
TLS3_k127_7187807_2 PFAM Sulfotransferase K01014 - 2.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 292.0
TLS3_k127_7187807_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003112 293.0
TLS3_k127_7187807_4 N-terminal double-transmembrane domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001636 230.0
TLS3_k127_7187807_5 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000001898 78.0
TLS3_k127_7190987_0 Belongs to the GcvT family K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 4.675e-251 798.0
TLS3_k127_7190987_1 Binding-protein-dependent transport system inner membrane component K02001 - - 3.847e-228 728.0
TLS3_k127_7190987_2 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 412.0
TLS3_k127_7190987_3 ATPases associated with a variety of cellular activities K02000 - 3.6.3.32 0.000009893 50.0
TLS3_k127_7216068_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 338.0
TLS3_k127_7216068_1 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.000000000000000000000000000000000000000000000000000001505 195.0
TLS3_k127_7216068_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000002895 192.0
TLS3_k127_7216068_3 Competence-damaged protein K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000338 167.0
TLS3_k127_7216068_4 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000004704 123.0
TLS3_k127_7216068_5 Autoinducer binding domain K18098 - - 0.00000000000003703 85.0
TLS3_k127_7226592_0 Phage terminase large subunit (GpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003935 265.0
TLS3_k127_7226592_1 Protein of unknown function (DUF3489) - - - 0.00000000000000000000000000000000002195 139.0
TLS3_k127_7226592_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000003338 133.0
TLS3_k127_7226592_3 Psort location Cytoplasmic, score - - - 0.000000000000003156 83.0
TLS3_k127_7235604_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 579.0
TLS3_k127_7235604_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 561.0
TLS3_k127_7235604_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 475.0
TLS3_k127_7235604_3 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 434.0
TLS3_k127_7235604_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 397.0
TLS3_k127_7235604_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000001878 61.0
TLS3_k127_7235604_6 Nodulation protein S (NodS) - - - 0.000001624 61.0
TLS3_k127_7252964_0 protein possibly involved in glyoxylate utilization K14977 - 3.5.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 420.0
TLS3_k127_7252964_1 Amidohydrolase family K18456 - 3.5.4.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 309.0
TLS3_k127_7252964_2 Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source K01483 - 4.3.2.3 0.0000000000000000000000000000000000000000000000004053 193.0
TLS3_k127_7268361_0 amidase activity K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 8.812e-308 960.0
TLS3_k127_7268361_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 524.0
TLS3_k127_7268361_2 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 444.0
TLS3_k127_7268361_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000009726 240.0
TLS3_k127_7268361_4 protein conserved in bacteria K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000009481 190.0
TLS3_k127_7287362_0 methylmalonate-semialdehyde dehydrogenase K00140 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 8.065e-283 873.0
TLS3_k127_7287362_1 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 561.0
TLS3_k127_7287362_10 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001039 303.0
TLS3_k127_7287362_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000006505 194.0
TLS3_k127_7287362_12 SnoaL-like domain - - - 0.0000000000000000000000000002308 119.0
TLS3_k127_7287362_13 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000002168 105.0
TLS3_k127_7287362_14 - - - - 0.000000000000000000002766 96.0
TLS3_k127_7287362_15 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000001504 68.0
TLS3_k127_7287362_16 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000005471 70.0
TLS3_k127_7287362_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 544.0
TLS3_k127_7287362_3 lactate/malate dehydrogenase, NAD binding domain K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 447.0
TLS3_k127_7287362_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 409.0
TLS3_k127_7287362_5 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 389.0
TLS3_k127_7287362_6 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 383.0
TLS3_k127_7287362_7 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 380.0
TLS3_k127_7287362_8 enoyl-CoA hydratase K00020,K01692 - 1.1.1.31,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 370.0
TLS3_k127_7287362_9 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 347.0
TLS3_k127_7308318_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 621.0
TLS3_k127_7308318_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 444.0
TLS3_k127_7308318_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 356.0
TLS3_k127_7308318_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 326.0
TLS3_k127_7308318_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001247 261.0
TLS3_k127_7308318_5 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000005115 179.0
TLS3_k127_7308318_6 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000004681 166.0
TLS3_k127_7308318_7 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.00000000000000000000000000000001196 130.0
TLS3_k127_7308318_8 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000001012 80.0
TLS3_k127_7324585_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1133.0
TLS3_k127_7324585_1 Superfamily II DNA K03654 - 3.6.4.12 7.231e-234 767.0
TLS3_k127_7324585_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000003779 147.0
TLS3_k127_7324585_11 Sulfotransferase family - - - 0.00000000000000000000000000000003446 138.0
TLS3_k127_7324585_12 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000002168 127.0
TLS3_k127_7324585_13 CrcB-like protein, Camphor Resistance (CrcB) - - - 0.00000000000000000001156 98.0
TLS3_k127_7324585_14 Sulfotransferase domain - - - 0.000000000000000178 89.0
TLS3_k127_7324585_15 - - - - 0.00000000000005918 86.0
TLS3_k127_7324585_16 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000001872 62.0
TLS3_k127_7324585_2 Reductase C-terminal K00529,K16968 - 1.14.13.111,1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 475.0
TLS3_k127_7324585_3 COG0695 glutaredoxin and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 415.0
TLS3_k127_7324585_4 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 358.0
TLS3_k127_7324585_5 Glycosyltransferase family 92 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 356.0
TLS3_k127_7324585_6 PFAM ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 340.0
TLS3_k127_7324585_7 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 331.0
TLS3_k127_7324585_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004708 291.0
TLS3_k127_7324585_9 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000376 219.0
TLS3_k127_7327311_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.016e-283 881.0
TLS3_k127_7327311_1 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 429.0
TLS3_k127_7327311_2 COG0303 Molybdopterin biosynthesis enzyme K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 331.0
TLS3_k127_7339650_0 FAD binding domain K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 456.0
TLS3_k127_7339650_1 glycosyl transferase family 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006084 246.0
TLS3_k127_7339650_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00004399 53.0
TLS3_k127_734384_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K21134 - - 2.928e-255 808.0
TLS3_k127_734384_1 protein conserved in bacteria K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 527.0
TLS3_k127_734384_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002097 260.0
TLS3_k127_734384_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000122 214.0
TLS3_k127_734384_4 COG0517 FOG CBS domain - - - 0.000000000000000000000000000000000000000005464 159.0
TLS3_k127_734384_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K20974 - 2.7.13.3 0.000000000000000000003302 98.0
TLS3_k127_734384_6 Cysteine-rich motif following a subset of SET domains K07117 - - 0.00002655 53.0
TLS3_k127_7346911_0 Carboxyl transferase domain K01969 - 6.4.1.4 9.668e-280 870.0
TLS3_k127_7346911_1 symporter activity K03307 - - 1.372e-206 653.0
TLS3_k127_7346911_2 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 1.252e-194 612.0
TLS3_k127_7346911_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 314.0
TLS3_k127_7346911_4 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 297.0
TLS3_k127_7346911_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000001834 225.0
TLS3_k127_7346911_6 COG3040 Bacterial lipocalin K03098 - - 0.000000000000000000000000000000000000000001483 162.0
TLS3_k127_7346911_7 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000007303 117.0
TLS3_k127_7346911_8 PIN domain - - - 0.00000000000000000001676 97.0
TLS3_k127_7346911_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768,K09565 - 5.2.1.8 0.0000000000000000004883 86.0
TLS3_k127_7349254_0 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000004336 229.0
TLS3_k127_7349254_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000001349 166.0
TLS3_k127_7349254_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000005312 130.0
TLS3_k127_7349254_3 Protein of unknown function (DUF983) - - - 0.00000000000000000000000528 103.0
TLS3_k127_7349254_4 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000866 79.0
TLS3_k127_7375648_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1500.0
TLS3_k127_7375648_1 Secreted protein - - - 0.000000000000000000000000000000000000000000000000000000000000001137 226.0
TLS3_k127_7375648_2 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000007241 212.0
TLS3_k127_7375648_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000005418 169.0
TLS3_k127_7375648_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000054 133.0
TLS3_k127_739323_0 Belongs to the RbsD FucU family K02431 - 5.1.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000002017 252.0
TLS3_k127_739323_1 COG2755 Lysophospholipase L1 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000004997 236.0
TLS3_k127_739323_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000002438 163.0
TLS3_k127_7394305_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 458.0
TLS3_k127_7394305_1 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 446.0
TLS3_k127_7394305_2 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000001723 162.0
TLS3_k127_7394305_3 Protein of unknown function (DUF1062) - - - 0.000000000000000000000000000000000000002545 156.0
TLS3_k127_7394305_4 belongs to the thioredoxin family - - - 0.000000000000000000000000000003546 139.0
TLS3_k127_7394305_5 PFAM MgtE intracellular - - - 0.00000000000000000000000002855 115.0
TLS3_k127_7394305_6 - - - - 0.0000000002611 69.0
TLS3_k127_7396345_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 408.0
TLS3_k127_7396345_1 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 399.0
TLS3_k127_7396345_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 380.0
TLS3_k127_7396345_3 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 294.0
TLS3_k127_7396345_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 282.0
TLS3_k127_7396345_5 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000193 265.0
TLS3_k127_7396345_6 Rhodanese-like domain - - - 0.00000000000000000000000002543 119.0
TLS3_k127_741529_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 505.0
TLS3_k127_741529_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 389.0
TLS3_k127_741529_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 306.0
TLS3_k127_741529_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000004392 249.0
TLS3_k127_741529_4 Methane oxygenase PmoA - - - 0.00000000000000000000003896 110.0
TLS3_k127_7424217_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1058.0
TLS3_k127_7424217_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - 0.000000000008229 68.0
TLS3_k127_7427715_0 Sulfotransferase family - - - 0.000000000000000000000000002354 122.0
TLS3_k127_7427715_1 Putative restriction endonuclease - - - 0.00000000000005742 81.0
TLS3_k127_7428148_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 554.0
TLS3_k127_7428148_1 Bacterial extracellular solute-binding protein K02064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 347.0
TLS3_k127_7428148_2 tRNA (Uracil-5-)-methyltransferase K00557,K03215 - 2.1.1.190,2.1.1.35 0.000000000000000000000000000000000003461 139.0
TLS3_k127_7428148_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.0000000000000000000000000000405 124.0
TLS3_k127_7435687_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.859e-242 754.0
TLS3_k127_7435687_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.721e-228 732.0
TLS3_k127_7435687_10 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000005007 211.0
TLS3_k127_7435687_11 membrane K08973 - - 0.00000000000000000000000000000000000000000000000000000006018 200.0
TLS3_k127_7435687_12 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000005067 173.0
TLS3_k127_7435687_13 Zinc-dependent metalloprotease - - - 0.00000000000000000000000000000000000001235 153.0
TLS3_k127_7435687_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 501.0
TLS3_k127_7435687_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 482.0
TLS3_k127_7435687_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 401.0
TLS3_k127_7435687_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 351.0
TLS3_k127_7435687_6 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 357.0
TLS3_k127_7435687_7 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 304.0
TLS3_k127_7435687_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000001212 258.0
TLS3_k127_7435687_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000001753 209.0
TLS3_k127_7443_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 392.0
TLS3_k127_7443_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 307.0
TLS3_k127_7443_2 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 297.0
TLS3_k127_7443_3 COG1886 Flagellar motor switch type III secretory pathway protein K02417 - - 0.0000000000000000000000004827 108.0
TLS3_k127_7443_4 FliG middle domain K02410 - - 0.00000000000000000576 98.0
TLS3_k127_745491_0 Glycosyl hydrolases family 43 K01198 - 3.2.1.37 1.878e-266 831.0
TLS3_k127_745491_1 dehydratase K01685,K01708 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008867,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0071704,GO:1901575 4.2.1.42,4.2.1.7 1.476e-231 758.0
TLS3_k127_745491_10 Sugar phosphate isomerases epimerases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 340.0
TLS3_k127_745491_11 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 340.0
TLS3_k127_745491_12 PFAM ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 326.0
TLS3_k127_745491_2 ABC-type sugar transport system, periplasmic component K17315 - - 4.513e-196 620.0
TLS3_k127_745491_3 ABC-type sugar transport system, permease component K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 546.0
TLS3_k127_745491_4 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 563.0
TLS3_k127_745491_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 512.0
TLS3_k127_745491_6 inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 516.0
TLS3_k127_745491_7 ABC-type transport system, periplasmic component surface lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 503.0
TLS3_k127_745491_8 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 497.0
TLS3_k127_745491_9 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 387.0
TLS3_k127_7472777_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 406.0
TLS3_k127_7472777_1 3-5 exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 311.0
TLS3_k127_7472777_2 Protein conserved in bacteria K11719 - - 0.00000000000000000001882 102.0
TLS3_k127_7475748_0 Flavoprotein involved in K transport K07222 - - 7.484e-213 668.0
TLS3_k127_7475748_1 Protein of unknown function (DUF993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 454.0
TLS3_k127_7475748_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 398.0
TLS3_k127_7475748_3 translation initiation inhibitor, yjgF family - - - 0.000000000000000000007858 91.0
TLS3_k127_749766_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.195e-228 714.0
TLS3_k127_749766_1 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000000000000000000000000000000005761 207.0
TLS3_k127_749766_2 integral membrane protein K02221 - - 0.00000000000000000000000000000000000004988 144.0
TLS3_k127_749766_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.0000000000000000000000000000000000008199 141.0
TLS3_k127_749766_4 PFAM Patatin K07001 - - 0.00000000000000000000000000005846 121.0
TLS3_k127_7498457_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 375.0
TLS3_k127_7498457_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 334.0
TLS3_k127_7498457_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001163 281.0
TLS3_k127_7521636_0 FtsX-like permease family K02004 - - 1.404e-314 984.0
TLS3_k127_7521636_1 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 556.0
TLS3_k127_7521636_2 transporter K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 401.0
TLS3_k127_7521636_3 transcriptional K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 404.0
TLS3_k127_7521636_4 ATPases associated with a variety of cellular activities K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 361.0
TLS3_k127_7521636_5 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 332.0
TLS3_k127_753038_0 VWA domain containing CoxE-like protein K09989 - - 3.365e-202 638.0
TLS3_k127_753038_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 337.0
TLS3_k127_753038_2 Protein of unknown function (DUF2927) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 314.0
TLS3_k127_753038_3 Peptidase family M48 K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 299.0
TLS3_k127_753038_4 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000172 242.0
TLS3_k127_753038_5 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000001896 207.0
TLS3_k127_7530523_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 619.0
TLS3_k127_7553784_0 Peptidase, M16 family protein K07263,K07623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 462.0
TLS3_k127_7553784_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000005685 158.0
TLS3_k127_7553784_2 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000004451 143.0
TLS3_k127_760931_0 Urate oxidase N-terminal - - - 1.746e-202 638.0
TLS3_k127_760931_1 Bacterial extracellular solute-binding protein K17315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 619.0
TLS3_k127_760931_2 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 557.0
TLS3_k127_760931_3 ABC transporter permease K17317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 483.0
TLS3_k127_760931_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 443.0
TLS3_k127_760931_5 Iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 404.0
TLS3_k127_760931_6 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 332.0
TLS3_k127_760931_7 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002796 253.0
TLS3_k127_760931_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000001963 110.0
TLS3_k127_7640091_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 457.0
TLS3_k127_7640091_1 CHASE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 403.0
TLS3_k127_764301_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 369.0
TLS3_k127_764301_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 0.00000000000000000000000000000000000000000005629 161.0
TLS3_k127_764301_2 Malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000005149 144.0
TLS3_k127_764301_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000004198 130.0
TLS3_k127_764301_4 RTX toxins and related Ca2 binding proteins - - - 0.000000000000000004583 95.0
TLS3_k127_7649409_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18307 - - 1.539e-268 837.0
TLS3_k127_7649409_1 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 589.0
TLS3_k127_7649409_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 433.0
TLS3_k127_7649409_3 GtrA-like protein - - - 0.000000000000000003335 91.0
TLS3_k127_7654220_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 329.0
TLS3_k127_7654220_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000001521 277.0
TLS3_k127_7654220_2 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000008191 237.0
TLS3_k127_7654220_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000007048 202.0
TLS3_k127_7654220_4 Outer membrane protein (OmpH-like) - - - 0.0000000000132 70.0
TLS3_k127_7659363_0 Cytochrome c-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 509.0
TLS3_k127_7659363_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 404.0
TLS3_k127_7659363_2 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000000003405 183.0
TLS3_k127_7680017_0 amino acid K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 407.0
TLS3_k127_7680017_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 325.0
TLS3_k127_7680017_2 Flagellar motor protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 312.0
TLS3_k127_7680017_3 B12-binding - - - 0.000000000000000000000000000006834 130.0
TLS3_k127_7680017_4 PRC-barrel domain - - - 0.00000000000000002973 96.0
TLS3_k127_7683318_0 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000000000000000000000000001767 194.0
TLS3_k127_7683318_1 Oligosaccharide biosynthesis protein Alg14 like - - - 0.000000000000000000000000000000000003111 143.0
TLS3_k127_7683318_2 Sensors of blue-light using FAD - - - 0.000001185 58.0
TLS3_k127_7684244_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 545.0
TLS3_k127_7684244_1 Sodium:sulfate symporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000006258 226.0
TLS3_k127_7684244_2 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000004151 217.0
TLS3_k127_7684244_3 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000006769 145.0
TLS3_k127_7693626_0 PFAM glycosyl transferase group 1 - - - 6.607e-221 694.0
TLS3_k127_7693626_1 TIGRFAM type I secretion system K06148,K16299 - - 2.869e-201 657.0
TLS3_k127_7693626_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 632.0
TLS3_k127_7693626_3 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 478.0
TLS3_k127_7693626_4 Type I secretion membrane fusion protein, HlyD K02022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 422.0
TLS3_k127_7693626_5 Beta-galactosidase - - - 0.0000000000000000000000000000000000000000001446 183.0
TLS3_k127_7715537_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000005781 171.0
TLS3_k127_7715537_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000002418 88.0
TLS3_k127_7715537_2 Metallo-beta-lactamase superfamily - - - 0.00000006135 65.0
TLS3_k127_7715537_3 Outer membrane protein, OmpA MotB, C-terminal - - - 0.0000002869 63.0
TLS3_k127_7715537_4 Winged helix DNA-binding domain - - - 0.0000004986 51.0
TLS3_k127_7746058_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 525.0
TLS3_k127_7746058_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 430.0
TLS3_k127_7746058_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 345.0
TLS3_k127_7746058_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 323.0
TLS3_k127_7746058_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001005 210.0
TLS3_k127_7746058_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377,K16554 - 1.1.1.271 0.00000000000000000000000000001612 130.0
TLS3_k127_7746058_6 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000002243 74.0
TLS3_k127_7752326_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 304.0
TLS3_k127_7752326_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000009564 224.0
TLS3_k127_7752326_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.00000000000000000008491 89.0
TLS3_k127_7752326_3 Transposase - - - 0.0000000000000002084 85.0
TLS3_k127_7780664_0 glycolate oxidase iron-sulfur subunit K11473 - - 1.517e-212 679.0
TLS3_k127_7780664_1 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 405.0
TLS3_k127_7780664_2 COG3591 V8-like Glu-specific endopeptidase - - - 0.000000009039 64.0
TLS3_k127_7796_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 508.0
TLS3_k127_7796_1 Protein of unknown function (DUF2849) - - - 0.00000000000000001346 97.0
TLS3_k127_7796_2 transcriptional regulator K05800 - - 0.00002662 48.0
TLS3_k127_7805601_0 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 474.0
TLS3_k127_7805601_1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 353.0
TLS3_k127_7805601_2 Sensors of blue-light using FAD - - - 0.0000000000006444 76.0
TLS3_k127_7805601_3 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000002982 68.0
TLS3_k127_7805601_4 Sensors of blue-light using FAD - - - 0.00004449 52.0
TLS3_k127_7806405_0 ABC-type multidrug transport system ATPase and permease K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 600.0
TLS3_k127_7806405_1 PFAM aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 466.0
TLS3_k127_7806405_2 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005821 257.0
TLS3_k127_7806405_3 G8 domain - - - 0.000000000000008844 79.0
TLS3_k127_7806405_4 Glycine zipper 2TM domain - - - 0.0001739 50.0
TLS3_k127_781_0 Acyl-CoA dehydrogenase type 2 domain K14448 - 1.3.8.12 9.345e-247 773.0
TLS3_k127_781_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.852e-221 694.0
TLS3_k127_781_2 COG1180 Pyruvate-formate lyase-activating enzyme K20449 - 1.3.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 579.0
TLS3_k127_781_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 496.0
TLS3_k127_781_4 Amino acid synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
TLS3_k127_781_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009738 275.0
TLS3_k127_781_6 Recombination protein O C terminal K03584 - - 0.0000000001271 64.0
TLS3_k127_7816148_0 Glycogen debranching enzyme - - - 4.196e-209 660.0
TLS3_k127_7816148_1 Iron-containing alcohol dehydrogenase K00001,K00043 - 1.1.1.1,1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 541.0
TLS3_k127_7816148_2 Belongs to the ABC transporter superfamily K10112 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001398 265.0
TLS3_k127_7816148_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 263.0
TLS3_k127_7816148_4 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002701 245.0
TLS3_k127_7816148_5 ABC-type transport system, permease components - - - 0.000000000000000000000000000000000000000000006241 173.0
TLS3_k127_7861842_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 363.0
TLS3_k127_7861842_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000528 247.0
TLS3_k127_7861842_2 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000002596 204.0
TLS3_k127_7861842_3 EamA-like transporter family - - - 0.00000000000000000000000007081 108.0
TLS3_k127_7861842_4 Molybdate ABC transporter substrate-binding protein K02020 - - 0.0004335 46.0
TLS3_k127_7874514_0 HWE histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 478.0
TLS3_k127_7874514_1 OpgC protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 347.0
TLS3_k127_7874514_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000000000000000000000003361 247.0
TLS3_k127_7874514_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000000000000000000001033 201.0
TLS3_k127_7874514_4 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000001658 143.0
TLS3_k127_7874514_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate K03701 - - 0.00000000000000000000000001103 112.0
TLS3_k127_7874514_6 acetyltransferase - - - 0.00000000000000000000001446 110.0
TLS3_k127_7879444_0 TIGRFAM 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1608.0
TLS3_k127_7879444_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1046.0
TLS3_k127_7879444_10 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000001212 166.0
TLS3_k127_7879444_11 Small Multidrug Resistance protein K11741 - - 0.000000000000000000000000000000000000002636 163.0
TLS3_k127_7879444_12 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000000000001105 152.0
TLS3_k127_7879444_13 TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000005312 134.0
TLS3_k127_7879444_14 Domain of unknown function (DUF1737) - - - 0.00000000000000000000000002195 109.0
TLS3_k127_7879444_15 - - - - 0.0000000000000000008879 93.0
TLS3_k127_7879444_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 2.353e-212 672.0
TLS3_k127_7879444_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 2.945e-204 641.0
TLS3_k127_7879444_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 557.0
TLS3_k127_7879444_5 dehydratase K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 522.0
TLS3_k127_7879444_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 517.0
TLS3_k127_7879444_7 Belongs to the HpcH HpaI aldolase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 331.0
TLS3_k127_7879444_8 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006464 268.0
TLS3_k127_7879444_9 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000001316 233.0
TLS3_k127_7887773_0 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002146 282.0
TLS3_k127_7887773_1 Cell wall hydrolyses involved in spore germination - - - 0.00000000000000000000000000000000000000000000005997 179.0
TLS3_k127_7887773_2 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000001093 150.0
TLS3_k127_7887773_3 peptidase inhibitor activity - - - 0.0000000000000202 82.0
TLS3_k127_7906788_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008153 272.0
TLS3_k127_7906788_1 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 - 2.7.8.33,2.7.8.35 0.0004975 47.0
TLS3_k127_791356_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 543.0
TLS3_k127_791356_1 RNA polymerase sigma K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 475.0
TLS3_k127_791356_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 387.0
TLS3_k127_791356_3 - - - - 0.0000000000003492 78.0
TLS3_k127_7966143_0 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 368.0
TLS3_k127_7966143_1 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 351.0
TLS3_k127_7966143_2 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008734 271.0
TLS3_k127_798813_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 475.0
TLS3_k127_798813_1 ATPases associated with a variety of cellular activities K01995,K11957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 356.0
TLS3_k127_798813_2 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 314.0
TLS3_k127_8002919_0 Sarcosine oxidase, beta subunit K00303,K22084 - 1.5.3.1,1.5.99.5 7.587e-214 670.0
TLS3_k127_8002919_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component K21393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 616.0
TLS3_k127_8002919_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 498.0
TLS3_k127_8002919_3 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 481.0
TLS3_k127_8002919_4 Periplasmic binding protein-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 314.0
TLS3_k127_8002919_5 TRAP-type C4-dicarboxylate transport system small permease component K21394 - - 0.000000000000000000000000000000000000000000000000000000000669 206.0
TLS3_k127_8002919_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000003252 113.0
TLS3_k127_8002919_7 Sarcosine oxidase, delta subunit K00304 - 1.5.3.1 0.0000000000000000000008417 96.0
TLS3_k127_8002919_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000009505 92.0
TLS3_k127_8008150_0 Inosine-uridine preferring nucleoside hydrolase K01239 GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008655,GO:0009056,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009164,GO:0009165,GO:0009435,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019357,GO:0019358,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0034356,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0045437,GO:0046135,GO:0046483,GO:0046496,GO:0046497,GO:0046700,GO:0050263,GO:0051186,GO:0051188,GO:0055086,GO:0070635,GO:0070636,GO:0071704,GO:0072521,GO:0072523,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 445.0
TLS3_k127_8008150_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 434.0
TLS3_k127_8008150_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 399.0
TLS3_k127_8008150_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 348.0
TLS3_k127_8008150_4 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000001156 198.0
TLS3_k127_8008150_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000006778 167.0
TLS3_k127_8008150_6 Protein of unknown function (DUF3035) - - - 0.000000000000000000000000001477 119.0
TLS3_k127_8032491_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 2.238e-204 646.0
TLS3_k127_8032491_1 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 440.0
TLS3_k127_8032491_2 Converts alpha-aldose to the beta-anomer K01785 GO:0003674,GO:0003824,GO:0004034,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 304.0
TLS3_k127_8032491_3 FeS assembly SUF system protein - - - 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
TLS3_k127_8032491_4 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000001472 184.0
TLS3_k127_8032491_5 Protein of unknown function (DUF3307) - - - 0.0000000000000000000000000000000000000000000000001084 195.0
TLS3_k127_8032491_6 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000001235 190.0
TLS3_k127_8032491_7 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000002616 149.0
TLS3_k127_8032491_8 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000002106 63.0
TLS3_k127_8047837_0 enoyl-CoA hydratase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1020.0
TLS3_k127_8047837_1 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 8.459e-274 854.0
TLS3_k127_8047837_2 Belongs to the thiolase family K00626 - 2.3.1.9 3.966e-212 664.0
TLS3_k127_8047837_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 284.0
TLS3_k127_8047837_4 Protein of unknown function (DUF861) - - - 0.0000000000000000000000000000000000000000000000000000000000004507 221.0
TLS3_k127_8047837_5 Cupin domain - - - 0.0000000000000000000000000000000000001056 156.0
TLS3_k127_8047837_6 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000000000000000000002052 149.0
TLS3_k127_8047837_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000004005 51.0
TLS3_k127_8062140_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 2.655e-238 766.0
TLS3_k127_8062140_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 401.0
TLS3_k127_8077385_0 Cellulose synthase K00694 - 2.4.1.12 5.072e-233 755.0
TLS3_k127_8077385_1 Hemolysin-type calcium-binding - - - 0.00000000000000000000000000000000000000000000000000000007221 214.0
TLS3_k127_8080810_0 YcjX-like family, DUF463 K06918 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 579.0
TLS3_k127_8080810_1 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 426.0
TLS3_k127_8080810_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 355.0
TLS3_k127_8080810_3 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000000000000000000002433 202.0
TLS3_k127_8080810_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000004884 184.0
TLS3_k127_8080810_5 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000001505 181.0
TLS3_k127_8080810_6 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000000000000000000000000001976 144.0
TLS3_k127_8080810_7 Protein of unknown function (DUF2945) - - - 0.00000000000000000000001242 102.0
TLS3_k127_8080810_8 membrane K08990 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000002436 67.0
TLS3_k127_8090535_0 Major Facilitator Superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 458.0
TLS3_k127_8090535_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 360.0
TLS3_k127_8090535_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 316.0
TLS3_k127_8090535_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 306.0
TLS3_k127_8090535_4 COG0524 Sugar kinases, ribokinase family K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002108 287.0
TLS3_k127_8090535_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000001995 162.0
TLS3_k127_8090535_6 Cold-shock protein K03704 - - 0.0000000000000000000000000000165 118.0
TLS3_k127_8109083_0 Glycosyl transferase family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 302.0
TLS3_k127_8109083_1 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000001315 69.0
TLS3_k127_8111014_0 Uncharacterized protein conserved in bacteria (DUF2090) K03338 - 2.7.1.92 0.0 1034.0
TLS3_k127_8111014_1 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 488.0
TLS3_k127_8111014_10 - - - - 0.00000000000000000741 92.0
TLS3_k127_8111014_11 Xylose isomerase-like TIM barrel K06605 - - 0.0000000000001321 70.0
TLS3_k127_8111014_2 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 397.0
TLS3_k127_8111014_3 KduI/IolB family K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000008327 203.0
TLS3_k127_8111014_4 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000001428 199.0
TLS3_k127_8111014_5 Sugar phosphate isomerases epimerases K06605 - - 0.00000000000000000000000000000000000000000000000000000003385 199.0
TLS3_k127_8111014_6 - - - - 0.00000000000000000000000000000000002892 139.0
TLS3_k127_8111014_7 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.000000000000000000000000000000004762 137.0
TLS3_k127_8111014_8 - - - - 0.0000000000000000000002321 108.0
TLS3_k127_8111014_9 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.0000000000000000000002703 104.0
TLS3_k127_8112118_0 COG0534 Na -driven multidrug efflux pump K03327 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 537.0
TLS3_k127_8112118_1 Thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005067 249.0
TLS3_k127_8112118_2 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000003578 191.0
TLS3_k127_8112118_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002702 171.0
TLS3_k127_8112118_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000691 112.0
TLS3_k127_8112118_5 - - - - 0.00000000000001948 77.0
TLS3_k127_8124622_0 Dehydroquinase class II K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000001013 205.0
TLS3_k127_8124622_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000001824 164.0
TLS3_k127_8124622_2 SOS response K14160 - - 0.0000931 46.0
TLS3_k127_8124651_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 457.0
TLS3_k127_8124651_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000003771 217.0
TLS3_k127_8124651_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000000004889 199.0
TLS3_k127_8125417_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000004329 222.0
TLS3_k127_8125417_1 Peroxiredoxin K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000002311 202.0
TLS3_k127_8135504_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001425 289.0
TLS3_k127_8146513_0 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000019 247.0
TLS3_k127_8146513_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000004383 225.0
TLS3_k127_8146513_2 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000003906 189.0
TLS3_k127_8146513_3 ThiS family K03636 - - 0.0000000000000000000000000000003428 124.0
TLS3_k127_8146513_4 Belongs to the ompA family K03286 - - 0.000000002025 60.0
TLS3_k127_8146513_5 - - - - 0.00001114 53.0
TLS3_k127_8158306_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.032e-208 655.0
TLS3_k127_8158306_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 488.0
TLS3_k127_8158306_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 344.0
TLS3_k127_8158306_3 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 345.0
TLS3_k127_8158306_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000002425 206.0
TLS3_k127_8158306_5 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000006556 203.0
TLS3_k127_8158306_6 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000003354 137.0
TLS3_k127_8158306_7 Anti-sigma-K factor rskA - - - 0.0000000000000000000000000000007361 136.0
TLS3_k127_8158306_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00003926 48.0
TLS3_k127_8200682_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 1.641e-238 744.0
TLS3_k127_8200682_1 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 464.0
TLS3_k127_820108_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.568e-254 814.0
TLS3_k127_820108_1 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 444.0
TLS3_k127_820108_2 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 397.0
TLS3_k127_820108_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000276 235.0
TLS3_k127_820108_4 TIGRFAM type I secretion outer membrane protein, TolC family K12340,K12535 - - 0.000000000000000000000000000002501 124.0
TLS3_k127_820108_5 PFAM Short-chain dehydrogenase reductase SDR K07535 - - 0.00000000000003618 87.0
TLS3_k127_8209143_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 375.0
TLS3_k127_8209143_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000003249 211.0
TLS3_k127_8209143_2 Histidine kinase - - - 0.0004464 51.0
TLS3_k127_8213804_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 513.0
TLS3_k127_8213804_1 membrane metal-binding protein K02238 - - 0.0000000000000000000000000000000000002015 160.0
TLS3_k127_8217776_0 gluconolactonase K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 490.0
TLS3_k127_8217776_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 481.0
TLS3_k127_8217776_2 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 450.0
TLS3_k127_8217776_3 Protein of unknown function (DUF3572) - - - 0.000003462 50.0
TLS3_k127_8230929_0 signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
TLS3_k127_8230929_1 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000307 228.0
TLS3_k127_8235095_0 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 552.0
TLS3_k127_8235095_1 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 558.0
TLS3_k127_8235095_2 abc transporter atp-binding protein K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 368.0
TLS3_k127_8235095_3 ABC transporter, (ATP-binding protein) K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 337.0
TLS3_k127_8235095_4 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.000002231 52.0
TLS3_k127_8243506_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 2.892e-194 620.0
TLS3_k127_8243506_1 Belongs to the UPF0262 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000172 253.0
TLS3_k127_8243506_2 Low molecular weight phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000002167 237.0
TLS3_k127_8243506_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000133 143.0
TLS3_k127_8243506_4 Domain of unknown function (DUF892) - - - 0.00000000000000000000000000000007396 132.0
TLS3_k127_8243506_5 TIGRFAM maf protein K06287 - - 0.000000000000000000000006737 104.0
TLS3_k127_8243607_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 2e-323 1005.0
TLS3_k127_8243607_1 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 539.0
TLS3_k127_8249755_0 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 386.0
TLS3_k127_8249755_1 HAD-superfamily subfamily IIA hydrolase like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 338.0
TLS3_k127_8249755_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002159 275.0
TLS3_k127_8249755_3 dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000001638 250.0
TLS3_k127_8249755_4 Putative zinc- or iron-chelating domain K09160 - - 0.000000000000000000000000000000000000000000000000000000001432 207.0
TLS3_k127_8249755_5 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000002009 208.0
TLS3_k127_8267817_0 Metallopeptidase family M24 - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016829,GO:0016846,GO:0042802,GO:0042803,GO:0046983,GO:0047869 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 572.0
TLS3_k127_8267817_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 385.0
TLS3_k127_8267817_2 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 316.0
TLS3_k127_8267817_3 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000003184 232.0
TLS3_k127_8267817_4 copG family - - - 0.00000000000000000000000000000000000000000000000002349 189.0
TLS3_k127_8267817_5 - - - - 0.00000000000000000000000000002029 129.0
TLS3_k127_8267817_6 COG1956 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000002173 82.0
TLS3_k127_8267817_7 Esterase PHB depolymerase K05972 - 3.1.1.72 0.00006711 46.0
TLS3_k127_8268251_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.224e-228 726.0
TLS3_k127_8268251_1 Protein of unknown function (DUF2793) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 402.0
TLS3_k127_8268251_2 DNA repair protein MmcB-like - - - 0.000000000000000000000000000000006321 140.0
TLS3_k127_8275712_0 With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner K02230 - 6.6.1.2 7.063e-291 923.0
TLS3_k127_8275712_1 Cobalamin synthesis protein cobW C-terminal domain K02234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 513.0
TLS3_k127_8275712_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 383.0
TLS3_k127_8275712_3 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 310.0
TLS3_k127_8275712_4 Protein of unknown function (DUF1636) - - - 0.00000000000000000000000000000000000000000000414 170.0
TLS3_k127_8275712_5 HupE / UreJ protein K03192 - - 0.0000000000000000000000000000000000000003424 171.0
TLS3_k127_8281333_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 586.0
TLS3_k127_8281333_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000227 188.0
TLS3_k127_8281333_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000006023 147.0
TLS3_k127_8286911_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 325.0
TLS3_k127_8286911_1 Peptidase M48 K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 308.0
TLS3_k127_8286911_2 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001421 256.0
TLS3_k127_8286911_3 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000001106 187.0
TLS3_k127_8286911_4 - - - - 0.0000000000000000000003795 101.0
TLS3_k127_8286911_5 VWA domain containing CoxE-like protein K09989 - - 0.0000008834 50.0
TLS3_k127_829069_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 436.0
TLS3_k127_829069_1 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 357.0
TLS3_k127_829069_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 334.0
TLS3_k127_829069_3 - - - - 0.000000000000000000000000000000000000000000000000000000002655 215.0
TLS3_k127_8293789_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 555.0
TLS3_k127_8293789_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000003698 123.0
TLS3_k127_8293789_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000008445 79.0
TLS3_k127_8307969_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0 1262.0
TLS3_k127_8307969_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 414.0
TLS3_k127_8307969_2 import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005908 271.0
TLS3_k127_8307969_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000000000008499 190.0
TLS3_k127_8307969_4 Smr protein MutS2 - - - 0.00000000000000000000000000000000000000001254 160.0
TLS3_k127_8307969_5 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.00000000000000000000000000000000000002063 149.0
TLS3_k127_8307969_6 protein conserved in bacteria - - - 0.000000000000000003423 91.0
TLS3_k127_8307969_7 PEP-CTERM motif - - - 0.0001436 51.0
TLS3_k127_833362_0 Biotin carboxylase C-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 5.913e-236 737.0
TLS3_k127_833362_1 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 331.0
TLS3_k127_833362_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003793 266.0
TLS3_k127_833362_3 Dsba oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001155 232.0
TLS3_k127_833362_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000000000000000000003275 196.0
TLS3_k127_833362_5 PFAM Aminotransferase class I and II - - - 0.00000000000000000003374 96.0
TLS3_k127_8336271_0 PFAM Acyl-CoA dehydrogenase - - - 4.963e-223 704.0
TLS3_k127_8336271_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000002207 236.0
TLS3_k127_8336271_2 Bacterial aa3 type cytochrome c oxidase subunit IV - - - 0.00000006963 55.0
TLS3_k127_8358488_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 599.0
TLS3_k127_8358488_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 587.0
TLS3_k127_8358488_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 522.0
TLS3_k127_8358488_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 325.0
TLS3_k127_8358488_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000001477 244.0
TLS3_k127_8358488_5 Methyltransferase domain - - - 0.0002758 45.0
TLS3_k127_835918_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1106.0
TLS3_k127_835918_1 COG3713 Outer membrane protein V K07274 - - 0.0000000000000000000000000000000000000000000000000000000000007497 228.0
TLS3_k127_835918_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000008492 157.0
TLS3_k127_835918_3 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000001769 161.0
TLS3_k127_835918_4 - - - - 0.0000000000000007711 79.0
TLS3_k127_8368440_0 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 368.0
TLS3_k127_8368440_1 PFAM Common central domain of tyrosinase K00505,K02674 - 1.14.18.1 0.000000000000000000000000000000000000000000000001429 184.0
TLS3_k127_8368440_2 DUF218 domain - - - 0.000000000000000000007931 100.0
TLS3_k127_8368440_3 - K00505 - 1.14.18.1 0.000000000000007848 87.0
TLS3_k127_839313_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 516.0
TLS3_k127_839313_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004882 227.0
TLS3_k127_839313_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000003107 180.0
TLS3_k127_839313_3 PIN domain - - - 0.000000000000000000000000000000000000003941 154.0
TLS3_k127_839313_4 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000003391 157.0
TLS3_k127_839313_5 SAM-dependent K06969 - 2.1.1.191 0.000000000001599 67.0
TLS3_k127_8404979_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000002805 203.0
TLS3_k127_8404979_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000002429 207.0
TLS3_k127_8404979_2 Chorismate mutase type II K04092 - 5.4.99.5 0.000000000000000000000000000000000000002928 151.0
TLS3_k127_8404979_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000002595 113.0
TLS3_k127_8424164_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 604.0
TLS3_k127_8424164_1 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 533.0
TLS3_k127_8424164_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 - 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 497.0
TLS3_k127_8424164_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 315.0
TLS3_k127_8424164_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 294.0
TLS3_k127_8424164_5 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000003428 236.0
TLS3_k127_8436151_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1118.0
TLS3_k127_8436151_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 411.0
TLS3_k127_8436151_2 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 358.0
TLS3_k127_8436151_3 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001143 256.0
TLS3_k127_8436151_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000006643 218.0
TLS3_k127_8438456_0 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 386.0
TLS3_k127_8438456_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 327.0
TLS3_k127_8438456_2 Protein of unknown function (DUF3108) - - - 0.000141 54.0
TLS3_k127_8443695_0 Bacterial extracellular solute-binding protein K02027 - - 2.167e-202 638.0
TLS3_k127_8443695_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 518.0
TLS3_k127_8443695_2 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 376.0
TLS3_k127_8443695_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 351.0
TLS3_k127_8443695_4 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001979 248.0
TLS3_k127_8443695_5 ROK family K13967 - 2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000001186 244.0
TLS3_k127_8443695_6 Putative N-acetylmannosamine-6-phosphate epimerase K13967 - 2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000001541 238.0
TLS3_k127_845168_0 Polyprenyl synthetase K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 469.0
TLS3_k127_845168_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 294.0
TLS3_k127_845168_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000007328 246.0
TLS3_k127_845168_3 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000005246 106.0
TLS3_k127_845168_4 Putative prokaryotic signal transducing protein - - - 0.00000000000000000004758 103.0
TLS3_k127_8473801_0 2Fe-2S iron-sulfur cluster binding domain - - - 5.293e-320 996.0
TLS3_k127_8473801_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 574.0
TLS3_k127_8473801_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 481.0
TLS3_k127_8473801_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 300.0
TLS3_k127_8473801_4 IclR helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000003996 218.0
TLS3_k127_8473801_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000116 152.0
TLS3_k127_8473801_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00001764 55.0
TLS3_k127_8475933_0 L-lactate permease K03303 - - 1.881e-295 915.0
TLS3_k127_8475933_1 Iron-sulfur cluster binding protein K18929 - - 3.147e-248 778.0
TLS3_k127_8475933_10 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000018 253.0
TLS3_k127_8475933_11 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000001196 193.0
TLS3_k127_8475933_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000257 89.0
TLS3_k127_8475933_13 Periplasmic or secreted lipoprotein - - - 0.00005061 52.0
TLS3_k127_8475933_2 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 605.0
TLS3_k127_8475933_3 beta-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 459.0
TLS3_k127_8475933_4 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 432.0
TLS3_k127_8475933_5 glycolate oxidase iron-sulfur subunit K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 406.0
TLS3_k127_8475933_6 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 408.0
TLS3_k127_8475933_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 383.0
TLS3_k127_8475933_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 337.0
TLS3_k127_8475933_9 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001236 269.0
TLS3_k127_8525016_0 alpha/beta hydrolase fold K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 325.0
TLS3_k127_8525016_1 PHB accumulation regulatory domain - - - 0.0000000000000000000000000000000000000000000000000005413 194.0
TLS3_k127_8525016_2 Peptidase M10 serralysin C terminal K01406 - 3.4.24.40 0.000005323 51.0
TLS3_k127_8547774_0 Belongs to the FGGY kinase family K00880 - 2.7.1.53 4.768e-219 691.0
TLS3_k127_8547774_1 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 625.0
TLS3_k127_8547774_2 Periplasmic binding protein-like domain K17202 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 509.0
TLS3_k127_8551033_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.753e-207 652.0
TLS3_k127_8551033_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000005058 231.0
TLS3_k127_879537_0 glutamine synthetase K01915 - 6.3.1.2 3.059e-207 653.0
TLS3_k127_879537_1 ABC-type sugar transport system, auxiliary component K09988 - 5.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 359.0
TLS3_k127_879537_2 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000000000000000003669 175.0
TLS3_k127_879537_3 CHAD - - - 0.0000000000000000000000000000000000000001871 156.0
TLS3_k127_880198_0 Aminotransferase K00813,K00832 - 2.6.1.1,2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 482.0
TLS3_k127_880198_1 Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 433.0
TLS3_k127_880198_2 ornithine cyclodeaminase K01750 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 346.0
TLS3_k127_880198_3 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 317.0
TLS3_k127_880198_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000008499 201.0
TLS3_k127_88959_0 ABC transporter substrate-binding protein K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 453.0
TLS3_k127_88959_1 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 358.0
TLS3_k127_88959_2 FAD linked oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 289.0
TLS3_k127_88959_3 NADPH-quinone reductase (modulator of drug activity B) K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000003206 248.0
TLS3_k127_88959_4 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000005775 220.0
TLS3_k127_895084_0 Helicase associated domain (HA2) Add an annotation K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 518.0
TLS3_k127_895084_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 494.0
TLS3_k127_895084_2 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 362.0
TLS3_k127_895084_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001638 155.0
TLS3_k127_895084_4 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000006031 136.0
TLS3_k127_895084_5 Common central domain of tyrosinase K00505 - 1.14.18.1 0.0000000000000000000000001246 118.0
TLS3_k127_898973_0 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 468.0
TLS3_k127_898973_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 435.0
TLS3_k127_898973_2 ATPase, AFG1 family K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 370.0
TLS3_k127_898973_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001981 216.0
TLS3_k127_906066_0 AMP-binding enzyme C-terminal domain K00666 - - 5.632e-236 740.0
TLS3_k127_906066_1 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000000002586 204.0
TLS3_k127_910160_0 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 437.0
TLS3_k127_910160_1 NADP oxidoreductase coenzyme F420-dependent K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 429.0
TLS3_k127_910160_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 432.0
TLS3_k127_910160_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 330.0
TLS3_k127_910160_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 308.0
TLS3_k127_910160_5 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000268 217.0
TLS3_k127_910160_6 Bacterial aa3 type cytochrome c oxidase subunit IV - - - 0.0008692 46.0
TLS3_k127_913655_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 539.0
TLS3_k127_913655_1 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 391.0
TLS3_k127_913655_2 BLUF domain protein - - - 0.000000382 58.0
TLS3_k127_913655_3 of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein - - - 0.000004082 56.0
TLS3_k127_921553_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1159.0
TLS3_k127_921553_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.293e-316 974.0
TLS3_k127_921553_10 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000228 134.0
TLS3_k127_921553_11 - - - - 0.000002281 53.0
TLS3_k127_921553_2 Carbamoyl-phosphate synthase L chain K01965 - 6.4.1.3 1.609e-303 946.0
TLS3_k127_921553_3 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 8.862e-288 895.0
TLS3_k127_921553_4 Protein of unknown function (DUF1214) - - - 1.947e-233 730.0
TLS3_k127_921553_5 Protein of unknown function (DUF1214) - - - 1.184e-197 646.0
TLS3_k127_921553_6 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
TLS3_k127_921553_7 - - - - 0.00000000000000000000000000000000000000000000000002434 183.0
TLS3_k127_921553_8 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000001543 166.0
TLS3_k127_921553_9 Domain of unknown function (DUF4174) - - - 0.0000000000000000000000000000000001483 139.0
TLS3_k127_924204_0 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 307.0
TLS3_k127_924204_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006068 272.0
TLS3_k127_924204_2 Stress-induced protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000214 255.0
TLS3_k127_924204_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
TLS3_k127_924204_4 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000002261 148.0
TLS3_k127_924204_5 PAS domain - - - 0.0000000000000000000000000000000002333 140.0
TLS3_k127_924204_6 Protein of unknown function (DUF3553) - - - 0.00000000000000006625 91.0
TLS3_k127_933738_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 4.809e-246 771.0
TLS3_k127_933738_1 COG2771 DNA-binding HTH domain-containing proteins K07782,K19731 - - 0.00000000000000000000000000000000000000000000000000000003048 205.0
TLS3_k127_937668_0 COG0665 Glycine D-amino acid oxidases (deaminating) K00303 - 1.5.3.1 4.279e-211 663.0
TLS3_k127_937668_1 Sarcosine oxidase subunit delta K00304 - 1.5.3.1 0.00000000000000000000000000000000000000000000000001986 181.0
TLS3_k127_937668_2 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000004152 190.0
TLS3_k127_937668_3 TIGRFAM sarcosine oxidase, alpha subunit family K00302 - 1.5.3.1 0.0000000000003288 76.0
TLS3_k127_959123_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 0.0 1118.0
TLS3_k127_959123_1 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 1.643e-239 754.0
TLS3_k127_959123_2 Haem-NO-binding - - - 0.0000000000000000000003369 101.0