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Overview

ID MAG04044
Name TLS3_bin.20
Sample SMP0105
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Myxococcia
Order Myxococcales
Family Anaeromyxobacteraceae
Genus DASSQI01
Species
Assembly information
Completeness (%) 79.49
Contamination (%) 2.81
GC content (%) 72.0
N50 (bp) 8,768
Genome size (bp) 2,671,911

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2440

Gene name Description KEGG GOs EC E-value Score Sequence
TLS3_k127_1007474_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 558.0
TLS3_k127_1007474_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 352.0
TLS3_k127_1007474_2 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002521 267.0
TLS3_k127_1007474_3 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000178 265.0
TLS3_k127_1039337_0 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 437.0
TLS3_k127_1039337_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 376.0
TLS3_k127_1039337_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002486 264.0
TLS3_k127_1039337_3 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000002123 232.0
TLS3_k127_1039337_4 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000004181 117.0
TLS3_k127_1043430_0 Cytochrome c - - - 7.021e-207 651.0
TLS3_k127_1043430_1 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 398.0
TLS3_k127_1043430_2 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009131 246.0
TLS3_k127_1043430_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000005366 210.0
TLS3_k127_1043430_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000005875 161.0
TLS3_k127_1043430_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000006769 62.0
TLS3_k127_1048646_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 450.0
TLS3_k127_1048646_1 Chromosome Partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 350.0
TLS3_k127_1048646_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 291.0
TLS3_k127_1048646_3 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001325 257.0
TLS3_k127_1048646_4 AAA domain - - - 0.00000000000000000000000000000000000001653 159.0
TLS3_k127_1048646_5 zinc-ribbon domain - - - 0.0000000000000000000000005928 117.0
TLS3_k127_1048646_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000159 68.0
TLS3_k127_1058851_0 ABC transporter transmembrane region K06147 - - 1.204e-223 707.0
TLS3_k127_1058851_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 529.0
TLS3_k127_1058851_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 520.0
TLS3_k127_1058851_3 Protein of unknown function (DUF1698) K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 406.0
TLS3_k127_1058851_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 366.0
TLS3_k127_1058851_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 292.0
TLS3_k127_1087596_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1037.0
TLS3_k127_1087596_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.113e-215 682.0
TLS3_k127_1087596_10 Protein of unknown function (DUF533) K11962 - - 0.00000000000000000000000000000000000000000000000000000000004657 222.0
TLS3_k127_1087596_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000001564 228.0
TLS3_k127_1087596_12 glyoxalase III activity - - - 0.00000000000000000000000000000003388 128.0
TLS3_k127_1087596_13 Putative methyltransferase - - - 0.0000000000000000000000000000009762 134.0
TLS3_k127_1087596_14 Glycosyltransferase family 87 - - - 0.00000006397 65.0
TLS3_k127_1087596_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 3.504e-194 612.0
TLS3_k127_1087596_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 576.0
TLS3_k127_1087596_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 606.0
TLS3_k127_1087596_5 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 568.0
TLS3_k127_1087596_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 540.0
TLS3_k127_1087596_7 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 379.0
TLS3_k127_1087596_8 hydrolase activity, acting on ester bonds K07051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008838 290.0
TLS3_k127_1087596_9 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000001621 218.0
TLS3_k127_1099786_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 530.0
TLS3_k127_1099786_1 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 516.0
TLS3_k127_1099786_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 427.0
TLS3_k127_1099786_3 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 386.0
TLS3_k127_1099786_4 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 364.0
TLS3_k127_1099786_5 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000009776 194.0
TLS3_k127_1099786_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000003956 197.0
TLS3_k127_1099786_7 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000003349 142.0
TLS3_k127_1099786_8 Cytochrome c K00406,K08906 - - 0.00002069 51.0
TLS3_k127_1139072_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.897e-296 940.0
TLS3_k127_1139072_1 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.642e-241 756.0
TLS3_k127_1139072_2 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 4.06e-213 674.0
TLS3_k127_1139072_3 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 605.0
TLS3_k127_1139072_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 564.0
TLS3_k127_1139072_5 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 518.0
TLS3_k127_1139072_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 333.0
TLS3_k127_1139072_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 307.0
TLS3_k127_1139072_8 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001106 239.0
TLS3_k127_1139072_9 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000000005252 133.0
TLS3_k127_1153711_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 502.0
TLS3_k127_1153711_1 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000007192 202.0
TLS3_k127_1153711_2 Sigma-70 region 2 K03088 - - 0.0000000000000000000000004527 115.0
TLS3_k127_1153711_4 cellulase activity - - - 0.00000105 62.0
TLS3_k127_1214769_0 peptidase U62 modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 528.0
TLS3_k127_1214769_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 422.0
TLS3_k127_1214769_2 ABC transporter K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 408.0
TLS3_k127_1214769_3 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 332.0
TLS3_k127_1214769_4 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 314.0
TLS3_k127_1214769_5 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 313.0
TLS3_k127_1214769_6 TIGRFAM molybdenum ABC transporter, periplasmic K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000004067 238.0
TLS3_k127_1214769_7 - - - - 0.0000000000000000000000000000000000000000000000000000002137 208.0
TLS3_k127_1230281_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.036e-198 624.0
TLS3_k127_1230281_1 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 533.0
TLS3_k127_1230281_2 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 548.0
TLS3_k127_1230281_3 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 432.0
TLS3_k127_1230281_4 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 375.0
TLS3_k127_1230281_5 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 365.0
TLS3_k127_1230281_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001501 273.0
TLS3_k127_1236878_0 Glycosyl transferase family 21 - - - 2.999e-239 749.0
TLS3_k127_1236878_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 547.0
TLS3_k127_1236878_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 409.0
TLS3_k127_1236878_3 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 329.0
TLS3_k127_1236878_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000012 228.0
TLS3_k127_1236878_5 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000002587 240.0
TLS3_k127_1245154_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1080.0
TLS3_k127_1245154_1 Sodium/hydrogen exchanger family K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 584.0
TLS3_k127_1245154_10 Domain of unknown function (DUF4198) - - - 0.0000000000005257 75.0
TLS3_k127_1245154_2 dioxygenase K15777 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 374.0
TLS3_k127_1245154_3 ABC transporter K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 343.0
TLS3_k127_1245154_4 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 307.0
TLS3_k127_1245154_5 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000001376 226.0
TLS3_k127_1245154_6 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000001758 229.0
TLS3_k127_1245154_8 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.0000000000000000000000000000000002382 143.0
TLS3_k127_1292646_0 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 476.0
TLS3_k127_1292646_1 Nucleoside recognition K06373 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 253.0
TLS3_k127_1292646_2 membrane protein required for spore maturation in B.subtilis K06374 - - 0.0000000000000000000000000000000000000000000000000000000000000006694 233.0
TLS3_k127_1292646_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000005766 216.0
TLS3_k127_1292646_4 Pfam:DUF955 K07110 - - 0.00000000000000000000000000000003281 125.0
TLS3_k127_1322027_0 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 565.0
TLS3_k127_1322027_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 461.0
TLS3_k127_1322027_10 PFAM flavin reductase domain protein FMN-binding - - - 0.0000000007493 62.0
TLS3_k127_1322027_2 phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 346.0
TLS3_k127_1322027_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 353.0
TLS3_k127_1322027_4 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000003631 211.0
TLS3_k127_1322027_5 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000005988 197.0
TLS3_k127_1322027_6 SAM-dependent methyltransferase - - - 0.00000000000000000000000000000000002477 147.0
TLS3_k127_1322027_7 - - - - 0.000000000000000000000000000009187 126.0
TLS3_k127_1322027_8 - - - - 0.00000000000000000000005541 113.0
TLS3_k127_1322027_9 Transcriptional regulator - - - 0.00000000000000005147 81.0
TLS3_k127_1330003_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 471.0
TLS3_k127_1330003_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 439.0
TLS3_k127_1330003_2 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
TLS3_k127_1330003_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 339.0
TLS3_k127_1330003_4 Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009548 261.0
TLS3_k127_1330003_7 - - - - 0.0000000000000000007393 86.0
TLS3_k127_1335022_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1480.0
TLS3_k127_1335022_1 AAA C-terminal domain K07478 - - 5.9e-223 713.0
TLS3_k127_1335022_2 May be involved in recombinational repair of damaged DNA K03631 - - 4.218e-210 669.0
TLS3_k127_1335022_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 453.0
TLS3_k127_1335022_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 391.0
TLS3_k127_1335022_5 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 340.0
TLS3_k127_1335022_6 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000005572 253.0
TLS3_k127_1393554_0 High confidence in function and specificity - - - 9.054e-312 980.0
TLS3_k127_1393554_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 321.0
TLS3_k127_1393554_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000002764 246.0
TLS3_k127_1422747_0 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 419.0
TLS3_k127_1422747_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 378.0
TLS3_k127_1422747_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 384.0
TLS3_k127_1422747_3 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000005864 154.0
TLS3_k127_1422747_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000001255 115.0
TLS3_k127_1422747_5 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000001449 103.0
TLS3_k127_1461697_0 ABC transporter K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 419.0
TLS3_k127_1461697_1 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 321.0
TLS3_k127_1461697_2 glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000001372 229.0
TLS3_k127_1461697_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000001103 177.0
TLS3_k127_1461697_4 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000002386 169.0
TLS3_k127_1461697_5 Sugar transferase - - - 0.0000000000000000000000002132 112.0
TLS3_k127_1472070_0 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 438.0
TLS3_k127_1472070_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 408.0
TLS3_k127_1472070_2 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 333.0
TLS3_k127_1472070_4 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000001317 157.0
TLS3_k127_1556583_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 410.0
TLS3_k127_1556583_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004118 279.0
TLS3_k127_1556583_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000004965 249.0
TLS3_k127_1556583_3 NifU-like N terminal domain - - - 0.00000000000000000000000000000000000003099 147.0
TLS3_k127_1556583_4 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000003631 131.0
TLS3_k127_1597530_0 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 602.0
TLS3_k127_1597530_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 531.0
TLS3_k127_1597530_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 477.0
TLS3_k127_1597530_3 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 449.0
TLS3_k127_1597530_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 447.0
TLS3_k127_1597530_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 334.0
TLS3_k127_1597530_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000007216 139.0
TLS3_k127_1597530_7 - - - - 0.0000000000000000003057 97.0
TLS3_k127_1616633_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1244.0
TLS3_k127_1616633_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 2.264e-229 716.0
TLS3_k127_1616633_10 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000000006011 194.0
TLS3_k127_1616633_11 zinc ion binding K06204 - - 0.00000000000000000000000000000000000000005708 159.0
TLS3_k127_1616633_12 nuclear chromosome segregation K03497 - - 0.000000000000000006992 91.0
TLS3_k127_1616633_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 7.759e-227 710.0
TLS3_k127_1616633_3 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 438.0
TLS3_k127_1616633_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 441.0
TLS3_k127_1616633_5 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 381.0
TLS3_k127_1616633_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 322.0
TLS3_k127_1616633_7 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 316.0
TLS3_k127_1616633_8 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 310.0
TLS3_k127_1616633_9 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 336.0
TLS3_k127_1623184_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 467.0
TLS3_k127_1623184_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 370.0
TLS3_k127_1623184_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 312.0
TLS3_k127_1623184_4 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000001095 275.0
TLS3_k127_1623184_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000002218 226.0
TLS3_k127_1623184_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000007162 170.0
TLS3_k127_1623184_7 regulation of DNA repair K03565 - - 0.00000000000000000000000000000000191 135.0
TLS3_k127_1643327_0 Histidine kinase A domain protein - - - 0.0 1056.0
TLS3_k127_1643327_1 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 406.0
TLS3_k127_1643327_2 PhoB family transcriptional regulator K02483 - - 0.00000000000000000003935 95.0
TLS3_k127_1643327_3 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000007925 78.0
TLS3_k127_1672198_0 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 476.0
TLS3_k127_1672198_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 456.0
TLS3_k127_1672198_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 395.0
TLS3_k127_1672198_3 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000003684 193.0
TLS3_k127_1672198_4 GtrA-like protein K00995 - 2.7.8.5 0.0000000000000000000000000000000000002332 151.0
TLS3_k127_1672198_5 Belongs to the GcvT family K06980 - - 0.00000000000000000003763 97.0
TLS3_k127_1685413_0 Histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 377.0
TLS3_k127_1685413_1 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 341.0
TLS3_k127_1685413_2 response regulator K15012 - - 0.000000000000000000000000000000000000000000000000000000000000000000001926 259.0
TLS3_k127_1685413_4 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000000001433 112.0
TLS3_k127_1685413_5 transglycosylase K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000003166 65.0
TLS3_k127_1686015_0 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 607.0
TLS3_k127_1686015_1 ATP-grasp domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 381.0
TLS3_k127_1686015_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 335.0
TLS3_k127_1686015_3 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000009317 231.0
TLS3_k127_1686015_4 PFAM lipopolysaccharide biosynthesis K08252,K16692 - 2.7.10.1 0.00000004055 62.0
TLS3_k127_1754016_0 Di-haem cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 601.0
TLS3_k127_1754016_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 456.0
TLS3_k127_1754016_2 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 434.0
TLS3_k127_1754016_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 301.0
TLS3_k127_1754016_4 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 270.0
TLS3_k127_1754016_5 Uncharacterised protein family (UPF0014) K02069 - - 0.000000000000000000000000000000000000000000000000000000006165 209.0
TLS3_k127_1754016_6 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000001292 128.0
TLS3_k127_1754016_7 - - - - 0.00000000000000005721 93.0
TLS3_k127_1754016_8 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000003859 73.0
TLS3_k127_1771747_0 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 622.0
TLS3_k127_1771747_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 432.0
TLS3_k127_1771747_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000004969 195.0
TLS3_k127_1771747_4 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000007796 172.0
TLS3_k127_1771747_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000002202 139.0
TLS3_k127_1771747_6 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000003996 132.0
TLS3_k127_1771747_7 PFAM ATP phosphoribosyltransferase - - - 0.000000000000000000000002914 117.0
TLS3_k127_1771747_8 Histidine kinase - - - 0.000000000000000000001062 105.0
TLS3_k127_1773159_0 twitching motility protein K02669 - - 5.721e-203 638.0
TLS3_k127_1773159_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 597.0
TLS3_k127_1773159_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 579.0
TLS3_k127_1773159_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 494.0
TLS3_k127_1773159_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 360.0
TLS3_k127_1773159_5 PilZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 353.0
TLS3_k127_1792968_0 Beta-eliminating lyase K01667 - 4.1.99.1 4.136e-248 792.0
TLS3_k127_1792968_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 415.0
TLS3_k127_1792968_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 306.0
TLS3_k127_1792968_3 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000006559 181.0
TLS3_k127_1792968_4 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000009601 175.0
TLS3_k127_1792968_5 PFAM Smr protein MutS2 - - - 0.00000000000000000000001413 115.0
TLS3_k127_1798256_0 Transcriptional regulator K03655,K10439,K11708 - 3.6.4.12 6.789e-233 729.0
TLS3_k127_1798256_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 581.0
TLS3_k127_1798256_2 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 338.0
TLS3_k127_1798256_3 PFAM ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 311.0
TLS3_k127_1798256_4 TIGRFAM DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003491 282.0
TLS3_k127_1798256_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002661 215.0
TLS3_k127_1798256_7 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000142 196.0
TLS3_k127_1798256_8 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000002638 170.0
TLS3_k127_1812385_0 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 549.0
TLS3_k127_1812385_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 399.0
TLS3_k127_1812385_2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 341.0
TLS3_k127_1812385_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 311.0
TLS3_k127_1812385_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 302.0
TLS3_k127_1812385_5 pseudouridine synthase activity K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000004757 255.0
TLS3_k127_1812385_6 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001086 250.0
TLS3_k127_1812385_7 - - - - 0.0000000000000000000000000000000000000000000000000002335 189.0
TLS3_k127_1812385_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000000000000009136 177.0
TLS3_k127_1812385_9 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000000000004606 97.0
TLS3_k127_182670_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 359.0
TLS3_k127_182670_1 Aldo keto reductase K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000135 274.0
TLS3_k127_182670_2 Domain of unknown function (DUF4142) K08995 - - 0.0001588 54.0
TLS3_k127_1831132_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.575e-297 924.0
TLS3_k127_1831132_1 CBS domain containing protein K07182 - - 1.667e-265 829.0
TLS3_k127_1831132_10 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001894 283.0
TLS3_k127_1831132_11 Oligoendopeptidase f - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002094 289.0
TLS3_k127_1831132_12 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000004684 263.0
TLS3_k127_1831132_14 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000005926 129.0
TLS3_k127_1831132_2 ubiquinol oxidase subunit I K00425 - 1.10.3.14 1.384e-220 691.0
TLS3_k127_1831132_3 Putative citrate transport - - - 3.276e-218 695.0
TLS3_k127_1831132_4 CBS domain containing protein K07182 - - 1.626e-205 656.0
TLS3_k127_1831132_5 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 597.0
TLS3_k127_1831132_6 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 470.0
TLS3_k127_1831132_7 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 433.0
TLS3_k127_1831132_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 369.0
TLS3_k127_1831132_9 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 364.0
TLS3_k127_1834509_0 TOBE domain K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 422.0
TLS3_k127_1834509_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 344.0
TLS3_k127_1834509_2 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002186 281.0
TLS3_k127_1834509_3 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002674 250.0
TLS3_k127_1834509_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000008466 189.0
TLS3_k127_1840139_0 CHASE3 domain - - - 4.665e-279 885.0
TLS3_k127_1840139_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 410.0
TLS3_k127_1840139_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 371.0
TLS3_k127_1840139_3 chemotaxis K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 331.0
TLS3_k127_1840139_4 methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000115 177.0
TLS3_k127_1840139_5 integral membrane protein - - - 0.0000000000000000000000000000000001073 147.0
TLS3_k127_1841378_0 PFAM sigma-54 factor interaction domain-containing protein K02688 - - 0.0 1071.0
TLS3_k127_1841378_1 cluster binding protein - - - 2.979e-303 951.0
TLS3_k127_1841378_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 309.0
TLS3_k127_1841378_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000001615 228.0
TLS3_k127_1841378_12 Adenylate Guanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000003343 224.0
TLS3_k127_1841378_13 - - - - 0.0000000000000000000000000000000000000000000000000000001606 214.0
TLS3_k127_1841378_14 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000001228 189.0
TLS3_k127_1841378_15 8 heme-binding sites - - - 0.0000000000000000000000000000000000000000000007175 173.0
TLS3_k127_1841378_16 - - - - 0.0000000000000000000000000000000000000000002131 169.0
TLS3_k127_1841378_17 - - - - 0.00000000000000000000000000000001082 136.0
TLS3_k127_1841378_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000001315 136.0
TLS3_k127_1841378_19 - - - - 0.00000000000000006928 94.0
TLS3_k127_1841378_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 602.0
TLS3_k127_1841378_20 metal cluster binding - - - 0.000000000000433 75.0
TLS3_k127_1841378_21 Protein of unknown function (DUF4242) - - - 0.000000001584 62.0
TLS3_k127_1841378_22 - - - - 0.0000007238 51.0
TLS3_k127_1841378_3 Aldehyde ferredoxin oxidoreductase K03738,K19515 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 584.0
TLS3_k127_1841378_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 544.0
TLS3_k127_1841378_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 431.0
TLS3_k127_1841378_6 PFAM sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 389.0
TLS3_k127_1841378_7 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 350.0
TLS3_k127_1841378_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 326.0
TLS3_k127_1841378_9 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 317.0
TLS3_k127_1906126_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 1.002e-196 633.0
TLS3_k127_1906126_1 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 351.0
TLS3_k127_1906126_2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008269 243.0
TLS3_k127_1906126_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000001681 207.0
TLS3_k127_1906126_4 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000000000000000000000000000001227 150.0
TLS3_k127_1906126_5 Diguanylate cyclase - - - 0.0000315 50.0
TLS3_k127_191023_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1351.0
TLS3_k127_191023_1 PFAM DNA primase small subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 550.0
TLS3_k127_191023_2 PFAM Asparaginase glutaminase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000001294 179.0
TLS3_k127_1917367_0 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 468.0
TLS3_k127_1917367_1 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 392.0
TLS3_k127_1917367_2 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 324.0
TLS3_k127_1933496_0 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 484.0
TLS3_k127_1933496_1 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 322.0
TLS3_k127_1933496_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000001368 139.0
TLS3_k127_1933496_4 - - - - 0.0001605 54.0
TLS3_k127_1961799_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.477e-288 894.0
TLS3_k127_1961799_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 1.048e-214 672.0
TLS3_k127_1961799_2 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 415.0
TLS3_k127_1961799_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 302.0
TLS3_k127_1961799_4 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005581 256.0
TLS3_k127_1961799_5 asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000003062 235.0
TLS3_k127_1961799_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000276 173.0
TLS3_k127_1961799_7 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000001342 170.0
TLS3_k127_1961799_8 Ferredoxin - - - 0.0000000000000000000000000000000003233 132.0
TLS3_k127_1961799_9 dehydrogenase - - - 0.0000138 49.0
TLS3_k127_1968545_0 aspartate glutamate uridylate kinase K00928 - 2.7.2.4 2.483e-253 788.0
TLS3_k127_1968545_1 Histidine ammonia-lyase K01745 - 4.3.1.3 1.184e-242 757.0
TLS3_k127_1968545_10 cysteine-type peptidase activity K13695 - - 0.00000000000000000000000000000000348 133.0
TLS3_k127_1968545_11 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000002718 112.0
TLS3_k127_1968545_12 peptidyl-tyrosine sulfation - - - 0.000000000000000000000002048 120.0
TLS3_k127_1968545_13 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000821 58.0
TLS3_k127_1968545_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 1.334e-229 722.0
TLS3_k127_1968545_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 578.0
TLS3_k127_1968545_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 569.0
TLS3_k127_1968545_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 548.0
TLS3_k127_1968545_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 512.0
TLS3_k127_1968545_7 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 511.0
TLS3_k127_1968545_8 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 393.0
TLS3_k127_1968545_9 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000001969 132.0
TLS3_k127_1995810_0 serine-type endopeptidase activity K04771,K08372 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 488.0
TLS3_k127_1995810_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 421.0
TLS3_k127_1995810_2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 415.0
TLS3_k127_1995810_3 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 369.0
TLS3_k127_1995810_4 PFAM Acyl-ACP thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000044 234.0
TLS3_k127_1995810_5 HAD-hyrolase-like K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000007833 233.0
TLS3_k127_2006348_0 Heat shock 70 kDa protein K04043 - - 0.0 1068.0
TLS3_k127_2006348_1 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 550.0
TLS3_k127_2006348_2 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 467.0
TLS3_k127_2006348_3 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 383.0
TLS3_k127_2006348_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 332.0
TLS3_k127_2006348_6 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000003361 124.0
TLS3_k127_2027229_0 Histidine kinase - - - 1.97e-258 835.0
TLS3_k127_2027229_1 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 595.0
TLS3_k127_2027229_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 503.0
TLS3_k127_2027229_3 Dolichyl-phosphate-mannose--protein K00728 GO:0000030,GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.109 0.0007555 45.0
TLS3_k127_2096277_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 494.0
TLS3_k127_2096277_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 313.0
TLS3_k127_2096277_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000674 277.0
TLS3_k127_2096277_3 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000000000000000000000000000000000005045 239.0
TLS3_k127_2096277_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000009957 222.0
TLS3_k127_2096277_5 Hydrogenase (NiFe) small subunit HydA K00534,K05927,K06282,K18008 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6 0.00000008492 63.0
TLS3_k127_2104186_0 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 7.4e-323 997.0
TLS3_k127_2104186_1 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 3.312e-229 719.0
TLS3_k127_2104186_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006617 283.0
TLS3_k127_2104186_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001129 271.0
TLS3_k127_2116854_0 PFAM Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000003111 207.0
TLS3_k127_2116854_1 protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000001334 190.0
TLS3_k127_2116854_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000483 165.0
TLS3_k127_2116854_3 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000005749 137.0
TLS3_k127_2116854_4 Protein of unknown function (DUF1059) - - - 0.0000000000000003111 81.0
TLS3_k127_2123607_0 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 5.258e-233 731.0
TLS3_k127_2123607_1 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 304.0
TLS3_k127_2123607_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000002865 143.0
TLS3_k127_2159648_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 7.759e-279 861.0
TLS3_k127_2159648_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 471.0
TLS3_k127_2159648_2 Bacterial membrane protein, YfhO - - - 0.0000000001638 68.0
TLS3_k127_2212454_0 membrane organization K03641 - - 0.0 1356.0
TLS3_k127_2212454_1 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 596.0
TLS3_k127_2212454_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 292.0
TLS3_k127_2212454_11 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 311.0
TLS3_k127_2212454_12 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002188 275.0
TLS3_k127_2212454_13 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000003915 205.0
TLS3_k127_2212454_14 Protein conserved in bacteria K09986 - - 0.000000000000000000000000000000000000000000000004187 177.0
TLS3_k127_2212454_15 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000001166 188.0
TLS3_k127_2212454_16 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000003419 141.0
TLS3_k127_2212454_18 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000003293 92.0
TLS3_k127_2212454_19 RES - - - 0.0000000001437 66.0
TLS3_k127_2212454_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 514.0
TLS3_k127_2212454_20 DnaJ molecular chaperone homology domain - - - 0.0000007014 62.0
TLS3_k127_2212454_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 499.0
TLS3_k127_2212454_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 462.0
TLS3_k127_2212454_5 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 403.0
TLS3_k127_2212454_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 404.0
TLS3_k127_2212454_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 360.0
TLS3_k127_2212454_8 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 374.0
TLS3_k127_2212454_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 305.0
TLS3_k127_2229526_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 9.052e-266 825.0
TLS3_k127_2229526_1 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 511.0
TLS3_k127_2229526_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 499.0
TLS3_k127_2229526_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000001063 226.0
TLS3_k127_2229526_6 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000001774 191.0
TLS3_k127_2229526_7 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000001642 147.0
TLS3_k127_2245516_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.879e-208 659.0
TLS3_k127_2245516_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 497.0
TLS3_k127_2245516_2 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 385.0
TLS3_k127_2245516_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 302.0
TLS3_k127_2245516_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000003717 223.0
TLS3_k127_2245516_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000005755 155.0
TLS3_k127_2245516_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000001418 151.0
TLS3_k127_2248614_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 400.0
TLS3_k127_2248614_1 COG2513 PEP phosphonomutase and related enzymes K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 362.0
TLS3_k127_2248614_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 320.0
TLS3_k127_2248614_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001279 289.0
TLS3_k127_2248614_4 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005107 281.0
TLS3_k127_2248614_5 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000004332 192.0
TLS3_k127_2248614_6 - - - - 0.000000000000000000000000009198 112.0
TLS3_k127_2248614_7 - - - - 0.0000000000000000002808 92.0
TLS3_k127_2248614_8 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000001602 86.0
TLS3_k127_2248614_9 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000001202 65.0
TLS3_k127_2271896_0 iron-sulfur binding K00184 - - 0.0 1104.0
TLS3_k127_2271896_1 Belongs to the ClpA ClpB family K03694 - - 1.198e-295 930.0
TLS3_k127_2271896_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000001329 200.0
TLS3_k127_2271896_11 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000005607 186.0
TLS3_k127_2271896_12 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000003887 143.0
TLS3_k127_2271896_13 - - - - 0.000000000000000000002071 109.0
TLS3_k127_2271896_2 Dienelactone hydrolase family - - - 2.491e-236 750.0
TLS3_k127_2271896_3 Polysulphide reductase K00185 - - 1.703e-213 717.0
TLS3_k127_2271896_4 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 479.0
TLS3_k127_2271896_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 467.0
TLS3_k127_2271896_6 Putative zinc-finger K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 390.0
TLS3_k127_2271896_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 361.0
TLS3_k127_2271896_8 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 349.0
TLS3_k127_2271896_9 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003425 289.0
TLS3_k127_2307766_0 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 474.0
TLS3_k127_2307766_1 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 377.0
TLS3_k127_2307766_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005544 275.0
TLS3_k127_2328462_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1193.0
TLS3_k127_2328462_1 Universal stress protein - - - 0.00000000000000000000000003505 115.0
TLS3_k127_2328462_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000001421 74.0
TLS3_k127_235031_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 3.635e-260 809.0
TLS3_k127_235031_1 Sodium:solute symporter family K14393 - - 5.129e-259 806.0
TLS3_k127_235031_2 Sugar (and other) transporter - - - 2.148e-251 818.0
TLS3_k127_235031_3 Cys Met metabolism K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 4.187e-209 654.0
TLS3_k127_235031_4 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 527.0
TLS3_k127_235031_5 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 442.0
TLS3_k127_235031_6 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 441.0
TLS3_k127_235031_7 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 394.0
TLS3_k127_235031_8 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000001463 188.0
TLS3_k127_235031_9 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000005563 135.0
TLS3_k127_2361452_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1062.0
TLS3_k127_2361452_1 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 475.0
TLS3_k127_2361452_10 Putative peptidoglycan binding domain - - - 0.00005146 53.0
TLS3_k127_2361452_2 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 426.0
TLS3_k127_2361452_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 376.0
TLS3_k127_2361452_4 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
TLS3_k127_2361452_5 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000005179 203.0
TLS3_k127_2361452_6 - - - - 0.000000000000000000000000000000000000000141 156.0
TLS3_k127_2361452_8 High confidence in function and specificity K07491 - - 0.000000000000001115 77.0
TLS3_k127_2361452_9 Uncharacterized ACR, COG1430 K09005 - - 0.00000006864 53.0
TLS3_k127_2361505_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 9.632e-221 699.0
TLS3_k127_2361505_1 Indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 583.0
TLS3_k127_2361505_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000002879 239.0
TLS3_k127_2361505_3 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000001694 179.0
TLS3_k127_2361505_4 High confidence in function and specificity K07491 - - 0.00000000000002684 73.0
TLS3_k127_2362290_0 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 464.0
TLS3_k127_2362290_1 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002133 290.0
TLS3_k127_2362290_2 nuclear chromosome segregation K03497 - - 0.00003967 55.0
TLS3_k127_2398178_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.641e-248 786.0
TLS3_k127_2398178_1 Heat shock 70 kDa protein K04043 - - 8.716e-244 761.0
TLS3_k127_2398178_10 Glutaredoxin K03676 - - 0.000000000000000002918 85.0
TLS3_k127_2398178_2 response regulator K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 377.0
TLS3_k127_2398178_3 serine-type endopeptidase activity K04772,K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 331.0
TLS3_k127_2398178_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005942 312.0
TLS3_k127_2398178_5 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002025 286.0
TLS3_k127_2398178_6 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005647 277.0
TLS3_k127_2398178_8 photoreceptor activity K11527 - 2.7.13.3 0.00000000000000000000000000000000003462 151.0
TLS3_k127_2441486_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 9.409e-210 674.0
TLS3_k127_2441486_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 417.0
TLS3_k127_2441486_2 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 419.0
TLS3_k127_2441486_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 405.0
TLS3_k127_2441486_4 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 357.0
TLS3_k127_2441486_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000005786 279.0
TLS3_k127_2441486_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000001113 214.0
TLS3_k127_2441486_7 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000000001003 196.0
TLS3_k127_2441486_8 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.00000000000000000000000000000001306 132.0
TLS3_k127_2534151_0 ABC transporter K02056 - 3.6.3.17 4.269e-254 792.0
TLS3_k127_2534151_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 1.628e-199 629.0
TLS3_k127_2534151_2 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 313.0
TLS3_k127_2534151_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000843 280.0
TLS3_k127_2542634_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 604.0
TLS3_k127_2542634_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000004499 229.0
TLS3_k127_2542634_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000006539 197.0
TLS3_k127_2542634_3 Recombinase zinc beta ribbon domain - - - 0.00002766 53.0
TLS3_k127_2570373_0 MMPL family K03296,K18138 - - 0.0 1596.0
TLS3_k127_2570373_1 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 607.0
TLS3_k127_2570373_10 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000006045 121.0
TLS3_k127_2570373_11 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000002218 98.0
TLS3_k127_2570373_2 RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 557.0
TLS3_k127_2570373_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 507.0
TLS3_k127_2570373_4 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 379.0
TLS3_k127_2570373_5 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001547 263.0
TLS3_k127_2570373_6 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000236 251.0
TLS3_k127_2570373_7 Bacterial regulatory proteins, tetR family K19736 - - 0.0000000000000000000000000000000000000000000000000000000000000002379 226.0
TLS3_k127_2570373_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000002844 156.0
TLS3_k127_2570373_9 - - - - 0.000000000000000000000000000001786 133.0
TLS3_k127_2585325_0 pseudouridine synthase activity K06176 - 5.4.99.27 2.037e-202 642.0
TLS3_k127_2585325_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 355.0
TLS3_k127_2585325_2 Domain of unknown function (DUF4265) - - - 0.0000000000000000000000000000000000000000000000002171 186.0
TLS3_k127_2585325_3 - - - - 0.000000000000000000000000002969 114.0
TLS3_k127_2585325_4 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000004492 69.0
TLS3_k127_2588139_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1407.0
TLS3_k127_2588139_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.827e-271 861.0
TLS3_k127_2588139_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 4.631e-220 698.0
TLS3_k127_2588139_3 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 482.0
TLS3_k127_2588139_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 407.0
TLS3_k127_2588139_6 nUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001439 282.0
TLS3_k127_2588139_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000007869 236.0
TLS3_k127_2590905_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.937e-267 826.0
TLS3_k127_2590905_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.49e-204 644.0
TLS3_k127_2590905_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 574.0
TLS3_k127_2590905_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 559.0
TLS3_k127_2590905_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 508.0
TLS3_k127_2590905_5 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 506.0
TLS3_k127_2590905_6 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 489.0
TLS3_k127_2590905_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 475.0
TLS3_k127_2590905_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001511 255.0
TLS3_k127_2590905_9 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000004279 216.0
TLS3_k127_2599012_0 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 589.0
TLS3_k127_2599012_1 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 557.0
TLS3_k127_2599012_2 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 524.0
TLS3_k127_2599012_3 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000836 308.0
TLS3_k127_2599012_4 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007517 253.0
TLS3_k127_2599012_5 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000003268 231.0
TLS3_k127_2599012_6 Polysaccharide deacetylase - - - 0.0000000000000000000000000000003146 134.0
TLS3_k127_2607010_0 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 0.0 1088.0
TLS3_k127_2607010_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.436e-276 865.0
TLS3_k127_2607010_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000004113 138.0
TLS3_k127_2607010_11 His Kinase A (phospho-acceptor) domain - - - 0.0002035 46.0
TLS3_k127_2607010_2 ubiquinol oxidase subunit I K00425 - 1.10.3.14 4.257e-205 647.0
TLS3_k127_2607010_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 4.808e-198 628.0
TLS3_k127_2607010_4 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 469.0
TLS3_k127_2607010_5 oxidase, subunit K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 445.0
TLS3_k127_2607010_6 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 325.0
TLS3_k127_2607010_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 307.0
TLS3_k127_2607010_8 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001482 261.0
TLS3_k127_2607010_9 signal-transduction protein containing cAMP-binding and CBS domains K00031,K02342,K14446 - 1.1.1.42,1.3.1.85,2.7.7.7 0.00000000000000000000000000000000000000000000002689 196.0
TLS3_k127_2628531_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 3.196e-194 610.0
TLS3_k127_2628531_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 586.0
TLS3_k127_2628531_10 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003454 267.0
TLS3_k127_2628531_11 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000001367 205.0
TLS3_k127_2628531_12 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000005404 184.0
TLS3_k127_2628531_13 Transmembrane anti-sigma factor - - - 0.00000000000000000000000000000000323 131.0
TLS3_k127_2628531_2 ABC transporter K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 482.0
TLS3_k127_2628531_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 472.0
TLS3_k127_2628531_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 458.0
TLS3_k127_2628531_5 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 416.0
TLS3_k127_2628531_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 404.0
TLS3_k127_2628531_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 398.0
TLS3_k127_2628531_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 327.0
TLS3_k127_2628531_9 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 321.0
TLS3_k127_2629794_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 413.0
TLS3_k127_2629794_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 390.0
TLS3_k127_2629794_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 286.0
TLS3_k127_2629794_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000006332 254.0
TLS3_k127_2629794_4 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005995 246.0
TLS3_k127_2630636_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0 1403.0
TLS3_k127_2630636_1 choline dehydrogenase activity - - - 1.773e-227 710.0
TLS3_k127_2630636_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 1.774e-198 620.0
TLS3_k127_2630636_3 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 547.0
TLS3_k127_2630636_4 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 490.0
TLS3_k127_2630636_5 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 482.0
TLS3_k127_2630636_6 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 380.0
TLS3_k127_2630636_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
TLS3_k127_2630636_8 membrane - - - 0.00000000000000000000000000000000000000005777 170.0
TLS3_k127_2645759_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 458.0
TLS3_k127_2645759_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 428.0
TLS3_k127_2645759_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 395.0
TLS3_k127_2662345_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.062e-300 934.0
TLS3_k127_2662345_1 Multicopper oxidase - - - 2.168e-251 794.0
TLS3_k127_2662345_2 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 452.0
TLS3_k127_2662345_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 350.0
TLS3_k127_2662345_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000002938 196.0
TLS3_k127_2662345_5 TIGRFAM hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000289 168.0
TLS3_k127_2662345_6 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000002422 152.0
TLS3_k127_2662345_7 SCO1/SenC - - - 0.0000000000000000000000000003127 132.0
TLS3_k127_2662345_8 - - - - 0.00000000000000001546 84.0
TLS3_k127_2672487_0 Belongs to the aldehyde dehydrogenase family K00128,K09472 - 1.2.1.3,1.2.1.99 1.944e-249 797.0
TLS3_k127_2672487_1 glutamine synthetase K01915 - 6.3.1.2 2.572e-238 742.0
TLS3_k127_2672487_2 alcohol dehydrogenase K00043 - 1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 529.0
TLS3_k127_2672487_3 Glycosyl Hydrolase Family 88 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 410.0
TLS3_k127_2672487_4 Peptidase C26 K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 255.0
TLS3_k127_2672487_5 light absorption - - - 0.0000000000000000007235 93.0
TLS3_k127_2681523_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 601.0
TLS3_k127_2681523_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 420.0
TLS3_k127_2681523_2 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000004874 247.0
TLS3_k127_2681523_3 PFAM amidohydrolase K20810 - 3.5.4.40 0.0000000000000000000000000000000001403 134.0
TLS3_k127_2681523_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000005437 117.0
TLS3_k127_2724841_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 2.717e-270 845.0
TLS3_k127_2724841_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 9.782e-260 807.0
TLS3_k127_2724841_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000003799 191.0
TLS3_k127_2724841_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000003076 177.0
TLS3_k127_2724841_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.0000000000000000000001364 102.0
TLS3_k127_2724841_5 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000004975 76.0
TLS3_k127_2724841_6 - - - - 0.0004091 51.0
TLS3_k127_2737818_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0 1042.0
TLS3_k127_2737818_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 5.529e-195 644.0
TLS3_k127_2737818_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 486.0
TLS3_k127_2737818_3 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 420.0
TLS3_k127_2737818_4 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000002414 209.0
TLS3_k127_2737818_5 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000005338 135.0
TLS3_k127_2737818_6 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000003093 119.0
TLS3_k127_2737818_7 Redoxin K03564 - 1.11.1.15 0.00000000000000000004628 90.0
TLS3_k127_2755790_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 8.659e-194 610.0
TLS3_k127_2755790_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 526.0
TLS3_k127_2755790_2 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 471.0
TLS3_k127_2755790_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 421.0
TLS3_k127_2755790_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 372.0
TLS3_k127_2755790_5 SMART Rhodanese domain protein - - - 0.00000000000003607 75.0
TLS3_k127_2781334_0 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 466.0
TLS3_k127_2781334_1 involved in molybdopterin and THIamine biosynthesis family 1 K03148,K21029,K22132 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.7.7.73,2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 385.0
TLS3_k127_2781334_2 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 342.0
TLS3_k127_2781334_3 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 343.0
TLS3_k127_2781334_4 Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 337.0
TLS3_k127_2781334_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 287.0
TLS3_k127_2783246_0 Belongs to the peptidase M16 family K07263 - - 6.057e-216 689.0
TLS3_k127_2783246_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 630.0
TLS3_k127_2783246_2 WYL domain K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 461.0
TLS3_k127_2783246_4 Protein of unknown function (DUF1054) - - - 0.0000000000000000000000000000000000000000000000000000000009248 224.0
TLS3_k127_2783246_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.0000000000000000000000000000000000000000000001365 169.0
TLS3_k127_2783246_6 Response regulator, receiver K03413 - - 0.00000000000000000000000000000000000000000007359 164.0
TLS3_k127_2783246_7 regulation of single-species biofilm formation K13572,K13573 - - 0.000000000000000001446 100.0
TLS3_k127_2828957_0 alcohol dehydrogenase K18012 - 1.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 507.0
TLS3_k127_2828957_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 501.0
TLS3_k127_2828957_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 318.0
TLS3_k127_2828957_3 Peptidase, M61 - - - 0.00000000000000000000000000000000000000003507 154.0
TLS3_k127_2868153_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1140.0
TLS3_k127_2868153_1 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0 1063.0
TLS3_k127_2868153_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 317.0
TLS3_k127_2868153_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000134 277.0
TLS3_k127_2868153_12 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007684 252.0
TLS3_k127_2868153_13 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000001476 231.0
TLS3_k127_2868153_14 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000001293 223.0
TLS3_k127_2868153_16 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000009294 172.0
TLS3_k127_2868153_18 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000543 113.0
TLS3_k127_2868153_19 - K07275 - - 0.000000000000000000000001013 115.0
TLS3_k127_2868153_2 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.71e-308 967.0
TLS3_k127_2868153_20 - - - - 0.00000000000000000002562 99.0
TLS3_k127_2868153_21 AMP binding - - - 0.0000000000000000009366 96.0
TLS3_k127_2868153_22 Rhodanese Homology Domain - - - 0.00000000000000003939 90.0
TLS3_k127_2868153_23 Carbohydrate binding domain - - - 0.000000000001031 79.0
TLS3_k127_2868153_24 - - - - 0.000000008995 64.0
TLS3_k127_2868153_25 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000007062 66.0
TLS3_k127_2868153_3 PFAM Carbon starvation protein CstA - - - 3.035e-240 761.0
TLS3_k127_2868153_4 Exonuclease K02342 - 2.7.7.7 8.615e-194 636.0
TLS3_k127_2868153_5 Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 603.0
TLS3_k127_2868153_6 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 551.0
TLS3_k127_2868153_7 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 527.0
TLS3_k127_2868153_8 Belongs to the D-alanine--D-alanine ligase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 498.0
TLS3_k127_2868153_9 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 411.0
TLS3_k127_2952555_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1126.0
TLS3_k127_2952555_1 Heat shock 70 kDa protein K04043 - - 2.614e-277 859.0
TLS3_k127_2952555_2 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 5.033e-276 853.0
TLS3_k127_2952555_3 Histidine kinase - - - 0.000000000009621 72.0
TLS3_k127_296344_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.121e-316 1000.0
TLS3_k127_296344_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 1.824e-250 784.0
TLS3_k127_296344_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 536.0
TLS3_k127_296344_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000007915 111.0
TLS3_k127_296344_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000002266 64.0
TLS3_k127_2972818_0 Methionine synthase K00548 - 2.1.1.13 0.0 1773.0
TLS3_k127_2972818_1 UPF0313 protein - - - 1.774e-304 944.0
TLS3_k127_2972818_10 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000007494 151.0
TLS3_k127_2972818_11 Domain of unknown function (DUF1844) - - - 0.000000000000000000000001158 117.0
TLS3_k127_2972818_13 Late embryogenesis abundant protein - - - 0.0000000000000008876 86.0
TLS3_k127_2972818_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 4.219e-219 699.0
TLS3_k127_2972818_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 614.0
TLS3_k127_2972818_4 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 580.0
TLS3_k127_2972818_5 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005496 284.0
TLS3_k127_2972818_6 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000008968 258.0
TLS3_k127_2972818_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000001136 240.0
TLS3_k127_2972818_8 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000001683 256.0
TLS3_k127_2972818_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000007242 186.0
TLS3_k127_2981138_0 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 538.0
TLS3_k127_2981138_1 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 437.0
TLS3_k127_2981138_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000001079 192.0
TLS3_k127_2981138_3 photoreceptor activity - - - 0.0000000000000000000002787 108.0
TLS3_k127_3038572_0 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 529.0
TLS3_k127_3038572_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 484.0
TLS3_k127_3038572_2 - - - - 0.00000000000000000000000000000000000000002534 159.0
TLS3_k127_3038572_3 Ribbon-helix-helix domain - - - 0.000000000000000000000000001068 113.0
TLS3_k127_3038572_4 peptidyl-tyrosine sulfation - - - 0.000000000001675 71.0
TLS3_k127_304232_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 447.0
TLS3_k127_304232_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 401.0
TLS3_k127_304232_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 312.0
TLS3_k127_304232_3 ABC transporter K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 309.0
TLS3_k127_304232_4 sodium ABC transporter, permease K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008866 289.0
TLS3_k127_3050074_0 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 4.599e-202 641.0
TLS3_k127_3050074_1 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 471.0
TLS3_k127_3050074_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 404.0
TLS3_k127_3050074_3 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 381.0
TLS3_k127_3050074_4 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004101 272.0
TLS3_k127_3050074_5 ATP-grasp enzyme - - - 0.00000000000000000000000000000000000000000000002896 186.0
TLS3_k127_3087591_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0 1082.0
TLS3_k127_3087591_1 COG NOG27188 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000006979 199.0
TLS3_k127_3087591_2 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000000000000000005453 154.0
TLS3_k127_3087591_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000246 140.0
TLS3_k127_3087591_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000003247 70.0
TLS3_k127_3111873_0 Heparinase II/III N-terminus - - - 1.674e-205 664.0
TLS3_k127_3111873_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 1.086e-202 656.0
TLS3_k127_3111873_2 protein kinase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 507.0
TLS3_k127_3111873_3 peptidase U62 modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000005932 221.0
TLS3_k127_3168521_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 311.0
TLS3_k127_3168521_1 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 289.0
TLS3_k127_3168521_3 - - - - 0.0000001968 55.0
TLS3_k127_3168521_4 - K04517 - 1.3.1.12 0.00001582 54.0
TLS3_k127_3175336_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.33e-197 616.0
TLS3_k127_3175336_1 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 402.0
TLS3_k127_3175336_2 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 392.0
TLS3_k127_3175336_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000001272 236.0
TLS3_k127_3175336_4 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000000001088 229.0
TLS3_k127_3175336_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
TLS3_k127_3175336_6 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000001365 111.0
TLS3_k127_3189830_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 1.049e-233 751.0
TLS3_k127_3189830_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 460.0
TLS3_k127_3189830_2 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 345.0
TLS3_k127_3189830_3 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 329.0
TLS3_k127_3189830_4 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 325.0
TLS3_k127_3189830_5 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 307.0
TLS3_k127_3189830_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000002056 203.0
TLS3_k127_3189830_8 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000007917 186.0
TLS3_k127_3189830_9 Thioredoxin-like - - - 0.000000000000000000001309 103.0
TLS3_k127_3202078_0 Domain of unknown function (DUF4091) - - - 1.197e-209 669.0
TLS3_k127_3202078_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 528.0
TLS3_k127_3202078_2 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 478.0
TLS3_k127_3202078_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 392.0
TLS3_k127_3202078_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 424.0
TLS3_k127_3202078_5 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.0000000000000000000000000000000000000000000000000000000000000006996 235.0
TLS3_k127_3202078_6 cellulose binding - - - 0.0000000000000000000000000000000000000000009298 179.0
TLS3_k127_3255680_0 Domain of unknown function (DUF4091) - - - 2.325e-211 674.0
TLS3_k127_3255680_1 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000001384 179.0
TLS3_k127_3266392_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 5.282e-281 882.0
TLS3_k127_3266392_1 Flagellar hook protein FlgE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 525.0
TLS3_k127_3266392_10 PFAM flagellar FlbD family protein K02385 - - 0.00000000135 66.0
TLS3_k127_3266392_2 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 330.0
TLS3_k127_3266392_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002071 280.0
TLS3_k127_3266392_4 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007038 276.0
TLS3_k127_3266392_5 NADPH quinone reductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005709 297.0
TLS3_k127_3266392_6 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000000000003534 195.0
TLS3_k127_3266392_7 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000002199 170.0
TLS3_k127_3284407_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 602.0
TLS3_k127_3284407_1 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 455.0
TLS3_k127_3284407_2 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 314.0
TLS3_k127_3284407_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000006874 245.0
TLS3_k127_3284758_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 569.0
TLS3_k127_3284758_1 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 491.0
TLS3_k127_3284758_2 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 424.0
TLS3_k127_3284758_3 PFAM ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 406.0
TLS3_k127_3284758_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 370.0
TLS3_k127_3284758_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 364.0
TLS3_k127_3284758_6 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000001315 217.0
TLS3_k127_3303654_0 pfam abc1 K03688 - - 3.515e-231 728.0
TLS3_k127_3303654_1 Belongs to the peptidase M16 family K07263 - - 1.412e-227 712.0
TLS3_k127_3303654_2 peptidase, M16 K07263,K07623 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 566.0
TLS3_k127_3303654_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 360.0
TLS3_k127_331082_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1535.0
TLS3_k127_331082_1 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 449.0
TLS3_k127_331082_2 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009464 424.0
TLS3_k127_331082_3 protein disulfide oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000003773 219.0
TLS3_k127_331082_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000004718 209.0
TLS3_k127_331082_5 thiolester hydrolase activity - - - 0.000005539 52.0
TLS3_k127_3322374_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1569.0
TLS3_k127_3322374_1 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 540.0
TLS3_k127_3322374_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 335.0
TLS3_k127_3322374_3 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000001802 246.0
TLS3_k127_3322374_4 membrane - - - 0.00000000000000000000000000000000005784 139.0
TLS3_k127_3322374_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000009947 129.0
TLS3_k127_3383511_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 524.0
TLS3_k127_3383511_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 451.0
TLS3_k127_3383511_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 349.0
TLS3_k127_3383511_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 302.0
TLS3_k127_3442728_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.265e-211 683.0
TLS3_k127_3442728_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 470.0
TLS3_k127_3442728_2 PQQ enzyme repeat K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 369.0
TLS3_k127_3442728_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 309.0
TLS3_k127_3442728_4 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 298.0
TLS3_k127_3442728_5 protein trimerization K15368 - - 0.0000000000000000000000000000000000000000000000000000000000000006369 228.0
TLS3_k127_3442728_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000005473 145.0
TLS3_k127_3521054_0 - - - - 2.437e-282 886.0
TLS3_k127_3521054_1 Alpha-amylase domain K01176 - 3.2.1.1 2.329e-195 633.0
TLS3_k127_3521054_2 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 581.0
TLS3_k127_3521054_3 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 453.0
TLS3_k127_3521054_4 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 367.0
TLS3_k127_3521054_5 C-terminal binding-module, SLH-like, of glucodextranase K01178 - 3.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 321.0
TLS3_k127_3521054_6 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000000000000000000000000000000000000000000000000000000000006894 247.0
TLS3_k127_3534744_0 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 399.0
TLS3_k127_3534744_1 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 391.0
TLS3_k127_3534744_2 CBS domain K04767,K07168,K07182 - - 0.0000000000000000000000000000000000000000000000000002428 191.0
TLS3_k127_3534744_3 Protoglobin - - - 0.000000000000000000000000000000000000000000000000003335 184.0
TLS3_k127_3534744_4 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.00000000000000000000000000000000000000539 160.0
TLS3_k127_3534744_5 dnak suppressor protein K06204 - - 0.00000000002327 76.0
TLS3_k127_3534744_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.00000002226 58.0
TLS3_k127_3534744_7 flagellar protein FliS K02422 - - 0.000001347 53.0
TLS3_k127_3549081_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 529.0
TLS3_k127_3549081_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 525.0
TLS3_k127_3549081_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 347.0
TLS3_k127_3549081_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000007642 145.0
TLS3_k127_3549081_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000007589 131.0
TLS3_k127_3549081_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000003866 102.0
TLS3_k127_3549081_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00004089 48.0
TLS3_k127_3583115_0 glutamine synthetase K01915 - 6.3.1.2 5.131e-254 788.0
TLS3_k127_3583115_1 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 481.0
TLS3_k127_3583115_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 459.0
TLS3_k127_3583115_3 Bacterial regulatory protein, Fis family K07712 - - 0.00000000000000000000000000000002688 144.0
TLS3_k127_3606758_0 cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 364.0
TLS3_k127_3606758_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00003766 56.0
TLS3_k127_3606758_2 helix_turn_helix, Lux Regulon - - - 0.0005876 47.0
TLS3_k127_3611441_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 491.0
TLS3_k127_3611441_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 440.0
TLS3_k127_3627184_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.283e-254 790.0
TLS3_k127_3627184_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 7.039e-235 733.0
TLS3_k127_3627184_2 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001402 292.0
TLS3_k127_3627184_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001339 239.0
TLS3_k127_3627184_4 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000003931 169.0
TLS3_k127_3627184_5 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000000001801 150.0
TLS3_k127_3627184_6 Sigma-54 interaction domain K07713,K07714,K07715 - - 0.0000000000000000000000000026 129.0
TLS3_k127_3632664_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 2.904e-244 770.0
TLS3_k127_3632664_1 family UPF0324 - - - 1.372e-238 748.0
TLS3_k127_3632664_10 - - - - 0.000000000000000000001826 98.0
TLS3_k127_3632664_2 domain protein K21147 - 2.7.7.80,2.8.1.11 2.373e-215 675.0
TLS3_k127_3632664_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 2.5e-211 663.0
TLS3_k127_3632664_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 570.0
TLS3_k127_3632664_5 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 518.0
TLS3_k127_3632664_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 464.0
TLS3_k127_3632664_7 Histidine kinase K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000001518 234.0
TLS3_k127_3632664_8 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000000000000000000000000000000000002728 212.0
TLS3_k127_3632664_9 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000009646 157.0
TLS3_k127_3645471_0 Elongation factor G, domain IV K02355 - - 0.0 1069.0
TLS3_k127_3645471_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.837e-288 895.0
TLS3_k127_3645471_10 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 336.0
TLS3_k127_3645471_11 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000001319 233.0
TLS3_k127_3645471_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000004811 177.0
TLS3_k127_3645471_13 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000003195 133.0
TLS3_k127_3645471_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 1.449e-265 829.0
TLS3_k127_3645471_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 7.775e-207 649.0
TLS3_k127_3645471_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.185e-205 667.0
TLS3_k127_3645471_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 528.0
TLS3_k127_3645471_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 421.0
TLS3_k127_3645471_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 386.0
TLS3_k127_3645471_8 PFAM glycosyl transferase family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 414.0
TLS3_k127_3645471_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 382.0
TLS3_k127_3656842_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1279.0
TLS3_k127_3656842_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.206e-300 936.0
TLS3_k127_3656842_10 MASE1 - - - 0.0000000002147 66.0
TLS3_k127_3656842_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 563.0
TLS3_k127_3656842_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 304.0
TLS3_k127_3656842_6 PFAM DivIVA family protein K04074 - - 0.000000000000000000000000000000000000000000000001283 183.0
TLS3_k127_3656842_7 Helix-turn-helix domain - - - 0.00000000000000000000000000325 115.0
TLS3_k127_3656842_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000008696 75.0
TLS3_k127_3656842_9 Tetratricopeptide repeat - - - 0.0000000001991 64.0
TLS3_k127_3663432_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.706e-240 746.0
TLS3_k127_3663432_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 512.0
TLS3_k127_3663432_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 329.0
TLS3_k127_3663432_3 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 318.0
TLS3_k127_3663432_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000002193 233.0
TLS3_k127_3663432_5 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000001172 233.0
TLS3_k127_3663432_6 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.00000000005753 74.0
TLS3_k127_3667690_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 542.0
TLS3_k127_3667690_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 519.0
TLS3_k127_3667690_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001908 280.0
TLS3_k127_3667690_3 - - - - 0.000000000000000000000000000000001271 138.0
TLS3_k127_3667690_4 regulation of translation K05809 - - 0.000000000003149 67.0
TLS3_k127_3667690_5 gas vesicle protein - - - 0.00002651 53.0
TLS3_k127_3667690_6 - - - - 0.0003443 44.0
TLS3_k127_3705693_0 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 480.0
TLS3_k127_3705693_1 pilus organization K07346 - - 0.0000000000000000000000000000000000000000000000000004435 191.0
TLS3_k127_3705693_2 - - - - 0.000000000000000003937 89.0
TLS3_k127_3705693_3 Bifunctional nuclease K08999 - - 0.000000000000001286 84.0
TLS3_k127_3705693_4 His Kinase A (phosphoacceptor) domain - - - 0.0001502 50.0
TLS3_k127_3729224_0 lipopolysaccharide transport K22110 - - 0.0 1354.0
TLS3_k127_3729224_1 gluconolactonase activity K01053 - 3.1.1.17 5.896e-204 650.0
TLS3_k127_3729224_2 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 514.0
TLS3_k127_3729224_3 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 555.0
TLS3_k127_3729224_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 414.0
TLS3_k127_3729224_5 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 290.0
TLS3_k127_3729224_6 Protein of unknown function, DUF417 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001944 246.0
TLS3_k127_3744140_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 398.0
TLS3_k127_3744140_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000002268 258.0
TLS3_k127_3744140_2 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001728 231.0
TLS3_k127_3744140_3 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000000000000000000002302 163.0
TLS3_k127_3744140_4 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.000000000000000000000000000008725 121.0
TLS3_k127_3744140_5 phosphorelay signal transduction system - - - 0.00000000000000000000000006513 121.0
TLS3_k127_3748444_0 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 576.0
TLS3_k127_3748444_1 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 492.0
TLS3_k127_3748444_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 484.0
TLS3_k127_3748444_3 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 351.0
TLS3_k127_3748444_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 312.0
TLS3_k127_3748444_5 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 280.0
TLS3_k127_3748444_6 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000002373 186.0
TLS3_k127_3748444_7 Protein of unknown function, DUF481 - - - 0.0000000000000000000000000000000000000000000000001144 188.0
TLS3_k127_3748444_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000007313 128.0
TLS3_k127_3756710_0 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 353.0
TLS3_k127_3756710_1 - - - - 0.00000000000000000000000000000000000000000000000001879 187.0
TLS3_k127_3756710_2 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000002465 148.0
TLS3_k127_3756710_3 DEAD DEAH box K03724 - - 0.00000000000000000009413 91.0
TLS3_k127_3786911_0 ABC transporter K15738 - - 3.341e-314 998.0
TLS3_k127_3786911_1 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 7.025e-220 706.0
TLS3_k127_3786911_10 cytochrome c biogenesis protein - - - 0.00000000000000000000001087 105.0
TLS3_k127_3786911_11 Domain of unknown function (DUF4143) - - - 0.000025 48.0
TLS3_k127_3786911_2 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 483.0
TLS3_k127_3786911_3 Polysaccharide biosynthesis protein K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 406.0
TLS3_k127_3786911_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 305.0
TLS3_k127_3786911_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004201 275.0
TLS3_k127_3786911_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002024 260.0
TLS3_k127_3786911_7 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008908 252.0
TLS3_k127_3786911_8 - - - - 0.0000000000000000000000000000000000000000000000000000000005576 208.0
TLS3_k127_3786911_9 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000002777 177.0
TLS3_k127_3787725_0 Bacteriophage N4 adsorption protein B K11740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 603.0
TLS3_k127_3787725_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000003854 145.0
TLS3_k127_3790328_0 Acetyl-coenzyme A transporter 1 K08218 - - 1.771e-243 761.0
TLS3_k127_3790328_1 DNA polymerase beta thumb K02347 - - 8.852e-243 763.0
TLS3_k127_3790328_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 453.0
TLS3_k127_3790328_3 Diadenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 435.0
TLS3_k127_3790328_4 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 403.0
TLS3_k127_3790328_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 384.0
TLS3_k127_3790328_6 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000001887 255.0
TLS3_k127_3790328_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000000000000000000001399 217.0
TLS3_k127_3790328_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000003279 168.0
TLS3_k127_3790328_9 Forkhead associated domain - - - 0.00000009561 53.0
TLS3_k127_3827119_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 475.0
TLS3_k127_3827119_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 462.0
TLS3_k127_3827119_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 417.0
TLS3_k127_3827119_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 387.0
TLS3_k127_3827119_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 371.0
TLS3_k127_3827119_5 FAD binding domain - - - 0.0000000000000859 74.0
TLS3_k127_3831978_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1053.0
TLS3_k127_3831978_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 475.0
TLS3_k127_3831978_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 321.0
TLS3_k127_3831978_3 General secretory system II, protein E domain protein K02454 - - 0.0000000000000000000000000000000000000000000000000000000000003409 213.0
TLS3_k127_3865607_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1159.0
TLS3_k127_3865607_1 GTP-binding protein K06207 - - 0.0 1056.0
TLS3_k127_3865607_2 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 497.0
TLS3_k127_3865607_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 323.0
TLS3_k127_3865607_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000000000001917 220.0
TLS3_k127_3865607_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000004144 181.0
TLS3_k127_3869741_0 ABC transporter C-terminal domain K06158 - - 1.775e-242 760.0
TLS3_k127_3869741_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 360.0
TLS3_k127_3869741_2 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001086 299.0
TLS3_k127_3869741_3 ATP-independent chaperone mediated protein folding - - - 0.000000000000000001033 96.0
TLS3_k127_3894273_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.318e-258 803.0
TLS3_k127_3894273_1 Asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 409.0
TLS3_k127_3894273_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 323.0
TLS3_k127_3894273_3 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 302.0
TLS3_k127_3894273_5 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000002422 239.0
TLS3_k127_38992_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 9.332e-219 702.0
TLS3_k127_38992_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 400.0
TLS3_k127_3900986_0 Aerotolerance regulator N-terminal - - - 4.072e-227 738.0
TLS3_k127_3900986_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 562.0
TLS3_k127_3900986_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 512.0
TLS3_k127_3900986_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 383.0
TLS3_k127_3900986_4 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 354.0
TLS3_k127_3900986_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
TLS3_k127_3917261_0 Type II and III secretion system protein K02453 - - 2.66e-295 927.0
TLS3_k127_3917261_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 5.66e-288 893.0
TLS3_k127_3917261_10 - - - - 0.0000000000000000000000007485 116.0
TLS3_k127_3917261_2 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 588.0
TLS3_k127_3917261_3 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 504.0
TLS3_k127_3917261_4 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002723 296.0
TLS3_k127_3917261_5 general secretion pathway protein K02456,K02457,K02650 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000002747 195.0
TLS3_k127_3917261_6 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000001074 177.0
TLS3_k127_3917261_7 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000000000000000000000000000000000000001659 185.0
TLS3_k127_3917261_8 Type II secretion system (T2SS), protein M K02462 - - 0.000000000000000000000000000000000000000000003605 184.0
TLS3_k127_3917261_9 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000000000000000000000000000002973 161.0
TLS3_k127_4021790_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.116e-226 747.0
TLS3_k127_4021790_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 7.737e-210 663.0
TLS3_k127_4021790_10 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000001199 127.0
TLS3_k127_4021790_11 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.0000000000000000000007841 101.0
TLS3_k127_4021790_2 Maltogenic Amylase, C-terminal domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 591.0
TLS3_k127_4021790_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 520.0
TLS3_k127_4021790_4 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 330.0
TLS3_k127_4021790_5 glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000005237 266.0
TLS3_k127_4021790_6 Alpha/beta hydrolase family K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000007067 225.0
TLS3_k127_4021790_7 Response regulator, receiver K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001342 238.0
TLS3_k127_4021790_8 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000003106 225.0
TLS3_k127_4021790_9 PFAM Conserved TM helix repeat-containing protein - - - 0.00000000000000000000000000000000000000000000001762 192.0
TLS3_k127_4024249_0 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 5e-324 1012.0
TLS3_k127_4024249_1 Voltage gated chloride channel K03281 - - 1.581e-232 733.0
TLS3_k127_4024249_2 Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 454.0
TLS3_k127_4024249_3 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 338.0
TLS3_k127_4024249_4 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003475 260.0
TLS3_k127_4024249_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000001441 148.0
TLS3_k127_4024249_6 DinB superfamily - - - 0.00000000000000000000000000000192 120.0
TLS3_k127_4024249_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000001185 69.0
TLS3_k127_4025115_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 4.699e-266 865.0
TLS3_k127_4025115_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 7.364e-264 821.0
TLS3_k127_4025115_10 PFAM Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 304.0
TLS3_k127_4025115_11 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 315.0
TLS3_k127_4025115_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 304.0
TLS3_k127_4025115_13 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002988 280.0
TLS3_k127_4025115_14 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000001326 241.0
TLS3_k127_4025115_15 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000000000000000000000000000000000000000002937 238.0
TLS3_k127_4025115_16 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000001213 126.0
TLS3_k127_4025115_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 1.091e-207 655.0
TLS3_k127_4025115_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 6.507e-205 648.0
TLS3_k127_4025115_4 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 490.0
TLS3_k127_4025115_5 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 465.0
TLS3_k127_4025115_6 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 417.0
TLS3_k127_4025115_7 Acyltransferase, ws dgat mgat K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 343.0
TLS3_k127_4025115_8 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 328.0
TLS3_k127_4025115_9 isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 316.0
TLS3_k127_4025599_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.187e-286 890.0
TLS3_k127_4025599_1 oligopeptide transporter, OPT family - - - 1.359e-218 685.0
TLS3_k127_4025599_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 262.0
TLS3_k127_4025599_3 glycosyl transferase family 8 - - - 0.000000000000000000000000006299 121.0
TLS3_k127_4036136_0 DNA helicase K03656,K03657 - 3.6.4.12 4.418e-302 939.0
TLS3_k127_4036136_1 TIGRFAM YidE YbjL duplication K07085 - - 1.302e-214 683.0
TLS3_k127_4036136_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 398.0
TLS3_k127_4036136_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000007437 237.0
TLS3_k127_4036136_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000587 224.0
TLS3_k127_4036136_5 Peptidase family M23 - - - 0.00004835 51.0
TLS3_k127_4045622_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 444.0
TLS3_k127_4045622_1 Dtw domain containing protein K05812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008578 268.0
TLS3_k127_4045622_2 response regulator K07685 - - 0.000000000000000000000000000000000000000000000000000000003521 225.0
TLS3_k127_4045622_3 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000002537 135.0
TLS3_k127_4045622_4 - - - - 0.000000000000000000000005581 109.0
TLS3_k127_4055778_0 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 612.0
TLS3_k127_4055778_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 477.0
TLS3_k127_4055778_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 386.0
TLS3_k127_4055778_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 344.0
TLS3_k127_4055778_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 287.0
TLS3_k127_4055778_5 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.000000000000000000000000000000000000000000000000002008 190.0
TLS3_k127_4055778_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000001885 126.0
TLS3_k127_4055778_8 antisigma factor binding K02066,K02660,K04749,K04757,K05946,K06378 - 2.4.1.187,2.7.11.1 0.00000000000004871 78.0
TLS3_k127_40747_0 PFAM Hemerythrin HHE cation binding domain K09155 - - 7.217e-229 724.0
TLS3_k127_40747_1 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 366.0
TLS3_k127_40747_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
TLS3_k127_40747_3 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 291.0
TLS3_k127_40747_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 293.0
TLS3_k127_40747_5 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000002236 224.0
TLS3_k127_40747_7 Cold-shock protein K03704 - - 0.00000000000000000000000000000007464 132.0
TLS3_k127_40747_9 SCP-2 sterol transfer family - - - 0.0003881 44.0
TLS3_k127_4075576_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 604.0
TLS3_k127_4075576_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 584.0
TLS3_k127_4075576_2 Histidine kinase K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000307 304.0
TLS3_k127_4075576_3 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000004009 233.0
TLS3_k127_408212_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1039.0
TLS3_k127_408212_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 594.0
TLS3_k127_408212_2 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000002686 109.0
TLS3_k127_408212_3 cell adhesion K02650 - - 0.0000000003122 70.0
TLS3_k127_4084623_0 CoA-substrate-specific enzyme activase - - - 1.284e-275 867.0
TLS3_k127_4084623_1 synthase K01858 - 5.5.1.4 1.609e-211 666.0
TLS3_k127_4084623_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 570.0
TLS3_k127_4084623_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003928 259.0
TLS3_k127_4084623_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002417 252.0
TLS3_k127_4084623_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000001516 215.0
TLS3_k127_4084623_6 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000004827 130.0
TLS3_k127_4084623_7 CHAD - - - 0.000000000000000000002934 98.0
TLS3_k127_4084623_8 cheY-homologous receiver domain - - - 0.000000000000000000003746 109.0
TLS3_k127_4089352_0 response regulator K02481,K07713 - - 7.828e-215 677.0
TLS3_k127_4089352_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 514.0
TLS3_k127_4089352_2 Protoglobin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 412.0
TLS3_k127_4089352_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 326.0
TLS3_k127_4089352_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 317.0
TLS3_k127_4089352_5 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 299.0
TLS3_k127_4089352_6 PAS sensor protein - - - 0.00000000000000000000000000000000000000000006903 181.0
TLS3_k127_4089352_7 Universal stress protein - - - 0.000000000000000000000000000000000000000001275 162.0
TLS3_k127_4089352_8 dnak suppressor protein K06204 - - 0.0000000000000000000000000000000001504 135.0
TLS3_k127_4131511_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 3.216e-208 663.0
TLS3_k127_4131511_1 PFAM Xanthine uracil vitamin C permease K02824 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 400.0
TLS3_k127_4131511_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 301.0
TLS3_k127_4131511_3 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009647 269.0
TLS3_k127_4131511_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000738 114.0
TLS3_k127_418397_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 2.319e-266 833.0
TLS3_k127_418397_1 CHASE - - - 1.994e-230 749.0
TLS3_k127_418397_10 adenosine 5'-monophosphoramidase activity - - - 0.000000000000000000000000000000000000000000000004328 176.0
TLS3_k127_418397_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000002077 181.0
TLS3_k127_418397_12 - - - - 0.00000000000000000000000000000000000000000002078 162.0
TLS3_k127_418397_13 Pfam 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000002729 173.0
TLS3_k127_418397_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000004897 138.0
TLS3_k127_418397_15 - - - - 0.000000000000000000000000000000001805 136.0
TLS3_k127_418397_17 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000124 76.0
TLS3_k127_418397_2 endonuclease activity K07451 - - 2.498e-200 642.0
TLS3_k127_418397_3 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 426.0
TLS3_k127_418397_4 Membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 404.0
TLS3_k127_418397_5 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 316.0
TLS3_k127_418397_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 322.0
TLS3_k127_418397_7 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000006576 235.0
TLS3_k127_418397_8 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000001402 212.0
TLS3_k127_418397_9 Thioesterase-like superfamily K02614 - - 0.0000000000000000000000000000000000000000000000009462 190.0
TLS3_k127_4249536_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.555e-213 668.0
TLS3_k127_4249536_1 DNA-binding transcriptional activator of the SARP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 466.0
TLS3_k127_4249536_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 351.0
TLS3_k127_4249536_3 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 329.0
TLS3_k127_4249536_4 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 267.0
TLS3_k127_4249536_5 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000000000000000000000000000000000003545 199.0
TLS3_k127_4249536_6 energy transducer activity K03832 - - 0.000001529 50.0
TLS3_k127_4277715_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1054.0
TLS3_k127_4277715_1 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 6.662e-295 913.0
TLS3_k127_4277715_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 4.497e-257 804.0
TLS3_k127_4277715_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 602.0
TLS3_k127_4277715_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 593.0
TLS3_k127_4277715_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 324.0
TLS3_k127_4277715_6 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001625 269.0
TLS3_k127_4277715_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001958 191.0
TLS3_k127_4277715_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000004192 127.0
TLS3_k127_4277715_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000815 78.0
TLS3_k127_4316761_0 Winged helix DNA-binding domain K09927 - - 1.462e-226 706.0
TLS3_k127_4316761_1 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 362.0
TLS3_k127_4316761_2 Pfam Response regulator receiver - - - 0.000000000000000121 84.0
TLS3_k127_4348834_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1362.0
TLS3_k127_4348834_1 Peptidase dimerisation domain - - - 9.016e-219 686.0
TLS3_k127_4348834_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001438 276.0
TLS3_k127_4348834_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000000001377 115.0
TLS3_k127_4356568_0 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 514.0
TLS3_k127_4356568_1 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 440.0
TLS3_k127_4356568_11 Belongs to the 'phage' integrase family - - - 0.000000000000614 72.0
TLS3_k127_4356568_2 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 298.0
TLS3_k127_4356568_3 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 276.0
TLS3_k127_4356568_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006214 251.0
TLS3_k127_4356568_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000003197 238.0
TLS3_k127_4356568_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000009607 237.0
TLS3_k127_4356568_7 MaoC like domain - - - 0.000000000000000000000000000000000000000007861 171.0
TLS3_k127_4356568_9 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000002442 113.0
TLS3_k127_4388465_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1069.0
TLS3_k127_4388465_1 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 481.0
TLS3_k127_4388465_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 308.0
TLS3_k127_4388465_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 323.0
TLS3_k127_441106_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.14e-258 806.0
TLS3_k127_441106_1 arsenical-resistance protein K03325 - - 3.452e-197 619.0
TLS3_k127_441106_2 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 405.0
TLS3_k127_441106_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 342.0
TLS3_k127_441106_4 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 309.0
TLS3_k127_441106_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000000000000003223 191.0
TLS3_k127_441106_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000008571 194.0
TLS3_k127_441106_7 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.000000000000000000000000000000000001131 155.0
TLS3_k127_441106_8 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000004009 84.0
TLS3_k127_4484882_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.506e-308 956.0
TLS3_k127_4484882_1 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 430.0
TLS3_k127_4484882_2 Cytochrome c K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 390.0
TLS3_k127_4484882_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000003014 239.0
TLS3_k127_4484882_4 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000008337 206.0
TLS3_k127_4484882_5 oxidase subunit K08738 - - 0.000000000000000000000000000000000000000000000107 182.0
TLS3_k127_4504996_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 1.793e-259 830.0
TLS3_k127_4504996_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 346.0
TLS3_k127_4504996_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000008662 142.0
TLS3_k127_4504996_11 Cytochrome c - - - 0.0000000000000000000000000002796 120.0
TLS3_k127_4504996_12 cheY-homologous receiver domain - - - 0.00000000000006612 76.0
TLS3_k127_4504996_13 - - - - 0.000000002149 70.0
TLS3_k127_4504996_2 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 344.0
TLS3_k127_4504996_3 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 311.0
TLS3_k127_4504996_4 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 262.0
TLS3_k127_4504996_5 cytochrome c oxidase K02351 - - 0.000000000000000000000000000000000000000000000000000000002485 223.0
TLS3_k127_4504996_6 regulation of translation K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000008875 214.0
TLS3_k127_4504996_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000009998 195.0
TLS3_k127_4504996_8 Cytochrome c oxidase subunit III - - - 0.00000000000000000000000000000000000000000000008256 194.0
TLS3_k127_4504996_9 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000006896 131.0
TLS3_k127_4534685_0 RNA polymerase sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 554.0
TLS3_k127_4534685_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 434.0
TLS3_k127_4534685_10 - - - - 0.0000000000000000000000001043 111.0
TLS3_k127_4534685_11 peroxiredoxin activity - - - 0.000000000007444 70.0
TLS3_k127_4534685_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 412.0
TLS3_k127_4534685_3 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 329.0
TLS3_k127_4534685_4 Nadph-dependent fmn reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 302.0
TLS3_k127_4534685_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005233 284.0
TLS3_k127_4534685_6 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
TLS3_k127_4534685_7 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002245 271.0
TLS3_k127_4534685_8 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000001583 230.0
TLS3_k127_4534685_9 - - - - 0.0000000000000000000000000000000000000006528 166.0
TLS3_k127_4555049_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 1.143e-199 627.0
TLS3_k127_4555049_1 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000001397 233.0
TLS3_k127_4555049_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.0000000000000000000000000000000000000000000000000000000000004365 214.0
TLS3_k127_4555049_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000003185 180.0
TLS3_k127_4555049_5 - - - - 0.0000000000000000000758 90.0
TLS3_k127_4555049_6 cellulase activity - - - 0.000000000002325 80.0
TLS3_k127_4574000_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 2.045e-224 703.0
TLS3_k127_4574000_1 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 471.0
TLS3_k127_4574000_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 414.0
TLS3_k127_4605516_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1320.0
TLS3_k127_4605516_1 Peptidase S46 - - - 5.513e-282 885.0
TLS3_k127_4605516_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.708e-253 782.0
TLS3_k127_4605516_3 PFAM Xanthine uracil vitamin C permease K06901 - - 3.194e-218 684.0
TLS3_k127_4605516_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 580.0
TLS3_k127_4605516_5 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 413.0
TLS3_k127_4605516_6 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
TLS3_k127_4626138_0 Peptidase family M20/M25/M40 K01270 - - 4.071e-222 697.0
TLS3_k127_4626138_1 DbpA RNA binding domain K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 559.0
TLS3_k127_4626138_2 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 312.0
TLS3_k127_4626138_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003341 264.0
TLS3_k127_4626138_4 COG NOG27188 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000003611 183.0
TLS3_k127_4626138_5 COG2076 Membrane transporters of cations and cationic drugs K11741 - - 0.00000000000000000008807 104.0
TLS3_k127_4660579_0 signal peptide peptidase SppA, 36K type K04773 - - 1.196e-225 726.0
TLS3_k127_4660579_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 8.445e-207 657.0
TLS3_k127_4660579_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 580.0
TLS3_k127_4660579_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005154 267.0
TLS3_k127_4676492_0 Domain of unknown function (DUF4175) - - - 4.46e-237 769.0
TLS3_k127_4676492_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 314.0
TLS3_k127_4676492_2 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000001745 139.0
TLS3_k127_4676492_5 Tetratricopeptide repeat - - - 0.000000000000000000000000177 117.0
TLS3_k127_4676492_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000001256 111.0
TLS3_k127_4784876_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 442.0
TLS3_k127_4784876_1 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 376.0
TLS3_k127_4784876_2 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 352.0
TLS3_k127_4784876_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000000000000001882 248.0
TLS3_k127_4784876_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000002441 219.0
TLS3_k127_4784876_5 Belongs to the UPF0434 family K09791 - - 0.000000000000000005993 87.0
TLS3_k127_4784876_6 - - - - 0.000000008204 57.0
TLS3_k127_4808980_0 Elongator protein 3, MiaB family, Radical SAM - - - 9.036e-266 852.0
TLS3_k127_4808980_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 464.0
TLS3_k127_4808980_2 COG1651 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000594 288.0
TLS3_k127_4808980_3 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000003225 192.0
TLS3_k127_4830991_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1196.0
TLS3_k127_4830991_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.311e-265 856.0
TLS3_k127_4830991_2 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 373.0
TLS3_k127_4830991_3 permease K20469 - - 0.00000000000000000000000000000000000000000000000000000000002217 219.0
TLS3_k127_4830991_4 PQQ enzyme repeat K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000000000001311 213.0
TLS3_k127_4830991_5 phosphate-selective porin O and P - - - 0.000000000000000000000000000007239 124.0
TLS3_k127_4830991_6 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 0.00000000000000000000000002869 115.0
TLS3_k127_487361_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.895e-205 645.0
TLS3_k127_487361_1 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 505.0
TLS3_k127_487361_2 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 424.0
TLS3_k127_487361_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000001772 126.0
TLS3_k127_487361_5 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.000000000000000000000000000006548 123.0
TLS3_k127_4902200_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0 1004.0
TLS3_k127_4902200_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.125e-279 868.0
TLS3_k127_4902200_2 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 584.0
TLS3_k127_4902200_3 Domain of unknown function (DUF4912) K09942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 299.0
TLS3_k127_490875_0 Heat shock 70 kDa protein K04043 - - 0.0 1021.0
TLS3_k127_490875_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 581.0
TLS3_k127_490875_2 ABC-type branched-chain amino acid transport K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 478.0
TLS3_k127_490875_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 481.0
TLS3_k127_490875_4 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006016 262.0
TLS3_k127_490875_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000002707 205.0
TLS3_k127_490875_6 photosynthesis K12132,K20543 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001944 199.0
TLS3_k127_490875_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000002625 186.0
TLS3_k127_4916267_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1120.0
TLS3_k127_4916267_1 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 564.0
TLS3_k127_4916267_10 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000002212 102.0
TLS3_k127_4916267_2 Alcohol dehydrogenase GroES domain protein K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 484.0
TLS3_k127_4916267_3 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 400.0
TLS3_k127_4916267_4 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 307.0
TLS3_k127_4916267_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000000000000000006079 226.0
TLS3_k127_4916267_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000001854 233.0
TLS3_k127_4916267_7 Uptake hydrogenase small subunit (Hydrogenlyase) (Membrane-bound hydrogenase small subunit) K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000003359 196.0
TLS3_k127_4916267_9 Hydrogenase nickel incorporation protein hypA K04651 - - 0.0000000000000000000002579 106.0
TLS3_k127_500560_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.943e-202 636.0
TLS3_k127_500560_1 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 330.0
TLS3_k127_500560_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000003698 270.0
TLS3_k127_500560_3 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000126 249.0
TLS3_k127_5046433_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.952e-317 987.0
TLS3_k127_5046433_1 Participates in both transcription termination and antitermination K02600 - - 1.726e-309 957.0
TLS3_k127_5046433_10 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 351.0
TLS3_k127_5046433_11 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 337.0
TLS3_k127_5046433_12 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 337.0
TLS3_k127_5046433_13 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005047 271.0
TLS3_k127_5046433_14 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000284 287.0
TLS3_k127_5046433_15 regulator K07773 - - 0.000000000000000000000000000000000000000000000000000000000000000299 226.0
TLS3_k127_5046433_16 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.000000000000000000000000000000000000000000000001172 175.0
TLS3_k127_5046433_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000004962 195.0
TLS3_k127_5046433_18 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000000000000007985 137.0
TLS3_k127_5046433_19 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000003304 126.0
TLS3_k127_5046433_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 4.499e-250 776.0
TLS3_k127_5046433_20 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000000000000002135 116.0
TLS3_k127_5046433_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.04e-227 730.0
TLS3_k127_5046433_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 620.0
TLS3_k127_5046433_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 527.0
TLS3_k127_5046433_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 467.0
TLS3_k127_5046433_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 427.0
TLS3_k127_5046433_8 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 391.0
TLS3_k127_5046433_9 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 377.0
TLS3_k127_5071141_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1105.0
TLS3_k127_5071141_1 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 3.682e-277 861.0
TLS3_k127_5071141_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.0000000000000000000000000000000000000013 169.0
TLS3_k127_5079766_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 3.888e-195 614.0
TLS3_k127_5079766_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 461.0
TLS3_k127_5079766_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 426.0
TLS3_k127_5079766_3 - - - - 0.00000000000000000000000000000000000000000006345 177.0
TLS3_k127_5097180_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.47e-281 874.0
TLS3_k127_5097180_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 573.0
TLS3_k127_5097180_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 444.0
TLS3_k127_5097180_3 COG0618 Exopolyphosphatase-related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 422.0
TLS3_k127_5097180_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 385.0
TLS3_k127_5097180_5 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 305.0
TLS3_k127_5097180_6 PTS system K02795 - - 0.00000000000000000000000000000000000000000000000000000000008704 211.0
TLS3_k127_5097180_7 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.000000000000000000000000000000000000000000000000000001314 195.0
TLS3_k127_5097180_8 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000001034 179.0
TLS3_k127_5097180_9 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000000000000000000001292 145.0
TLS3_k127_5104134_0 DEAD DEAH box helicase - - - 0.0 1300.0
TLS3_k127_5104134_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1205.0
TLS3_k127_5104134_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 381.0
TLS3_k127_5104134_3 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 289.0
TLS3_k127_5104134_4 Glutathione S-transferase K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000001513 250.0
TLS3_k127_5104134_5 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000004385 250.0
TLS3_k127_5104134_6 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.0000000000000000000000000000000000000000001991 164.0
TLS3_k127_5104134_7 transmembrane signaling receptor activity K03406 - - 0.0000000000000000000000000005143 124.0
TLS3_k127_510735_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1424.0
TLS3_k127_510735_1 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 580.0
TLS3_k127_510735_2 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 540.0
TLS3_k127_510735_3 Cell division protein FtsI penicillin-binding protein 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 459.0
TLS3_k127_510735_4 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 421.0
TLS3_k127_510735_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000002259 123.0
TLS3_k127_5166206_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 3.28e-226 705.0
TLS3_k127_5166206_1 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000003405 183.0
TLS3_k127_5166206_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000003849 150.0
TLS3_k127_5187218_0 Belongs to the heme-copper respiratory oxidase family K15408 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 468.0
TLS3_k127_5187218_1 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 379.0
TLS3_k127_5187218_2 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009193 259.0
TLS3_k127_5198822_0 Cytochrome C assembly protein - - - 3.044e-283 894.0
TLS3_k127_5198822_1 pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 344.0
TLS3_k127_5198822_10 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000001245 254.0
TLS3_k127_5198822_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000003928 235.0
TLS3_k127_5198822_12 PFAM Receptor family ligand binding region K01999 - - 0.0000000000000000000000000005773 120.0
TLS3_k127_5198822_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 332.0
TLS3_k127_5198822_3 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 336.0
TLS3_k127_5198822_4 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 301.0
TLS3_k127_5198822_5 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001005 277.0
TLS3_k127_5198822_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 273.0
TLS3_k127_5198822_7 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001474 251.0
TLS3_k127_5198822_8 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008579 272.0
TLS3_k127_5198822_9 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004009 251.0
TLS3_k127_5207152_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1091.0
TLS3_k127_5207152_1 Domain of unknown function (DUF3413) K07014 - - 4.28e-246 779.0
TLS3_k127_5207152_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 1.865e-209 664.0
TLS3_k127_5207152_3 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 405.0
TLS3_k127_5207152_4 Related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002924 268.0
TLS3_k127_5207152_5 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002657 268.0
TLS3_k127_5207152_6 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006037 244.0
TLS3_k127_5207152_7 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000002386 139.0
TLS3_k127_5220284_0 Major Facilitator Superfamily - - - 6.545e-215 679.0
TLS3_k127_5220284_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 385.0
TLS3_k127_5220284_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 352.0
TLS3_k127_5220284_3 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 343.0
TLS3_k127_5220284_4 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001761 250.0
TLS3_k127_5220284_5 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000003724 221.0
TLS3_k127_5220284_6 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000007182 226.0
TLS3_k127_5220284_7 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000004312 141.0
TLS3_k127_5220284_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000001404 121.0
TLS3_k127_5223563_0 DNA-dependent DNA replication K02315,K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 462.0
TLS3_k127_5223563_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003075 261.0
TLS3_k127_5223563_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001735 263.0
TLS3_k127_5223563_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000001163 229.0
TLS3_k127_5223563_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000001304 178.0
TLS3_k127_5223563_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000002681 159.0
TLS3_k127_5242943_0 PFAM Pyridoxal-dependent decarboxylase K01593 - 4.1.1.105,4.1.1.28 1.058e-214 680.0
TLS3_k127_5242943_1 Amidohydrolase K07045 - - 6.959e-213 672.0
TLS3_k127_5242943_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 414.0
TLS3_k127_5242943_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000007144 208.0
TLS3_k127_5242943_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000001074 181.0
TLS3_k127_5242943_5 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000001988 143.0
TLS3_k127_5254246_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1030.0
TLS3_k127_5254246_1 PFAM AMP-dependent synthetase and ligase - - - 9.24e-322 998.0
TLS3_k127_5254246_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 361.0
TLS3_k127_5254246_11 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 307.0
TLS3_k127_5254246_12 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K06950 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000001572 260.0
TLS3_k127_5254246_13 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002626 243.0
TLS3_k127_5254246_14 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004818 247.0
TLS3_k127_5254246_15 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000003331 241.0
TLS3_k127_5254246_16 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000000000000000000001968 165.0
TLS3_k127_5254246_19 - - - - 0.0000000000000000001469 101.0
TLS3_k127_5254246_2 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase K01236 - 3.2.1.141 1.196e-231 732.0
TLS3_k127_5254246_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 2.19e-199 634.0
TLS3_k127_5254246_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 632.0
TLS3_k127_5254246_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 523.0
TLS3_k127_5254246_6 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 486.0
TLS3_k127_5254246_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 449.0
TLS3_k127_5254246_8 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 414.0
TLS3_k127_5254246_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 394.0
TLS3_k127_5275381_0 SMART Elongator protein 3 MiaB NifB - - - 1.013e-244 763.0
TLS3_k127_5275381_1 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 613.0
TLS3_k127_5285381_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.601e-257 803.0
TLS3_k127_5285381_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 543.0
TLS3_k127_5285381_10 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000089 68.0
TLS3_k127_5285381_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 417.0
TLS3_k127_5285381_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 407.0
TLS3_k127_5285381_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 402.0
TLS3_k127_5285381_5 Prokaryotic glutathione synthetase, ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 366.0
TLS3_k127_5285381_6 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 366.0
TLS3_k127_5285381_7 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001075 245.0
TLS3_k127_5285381_8 Small hydrophilic plant seed protein - - - 0.000000000000000000000000000000000000000007529 159.0
TLS3_k127_5291427_0 Aminotransferase K01845 - 5.4.3.8 2.528e-212 664.0
TLS3_k127_5291427_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 485.0
TLS3_k127_5291427_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002816 286.0
TLS3_k127_5291427_3 ATP synthesis coupled proton transport K02109 - - 0.000000000000000000000000000000000000000000000000000000000000003797 222.0
TLS3_k127_5291427_5 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000276 118.0
TLS3_k127_5305685_0 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 477.0
TLS3_k127_5305685_1 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005377 266.0
TLS3_k127_5305685_2 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000000000002301 182.0
TLS3_k127_5305685_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000008259 162.0
TLS3_k127_5305685_4 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000008634 140.0
TLS3_k127_5305685_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000001493 74.0
TLS3_k127_5316467_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 529.0
TLS3_k127_5316467_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 424.0
TLS3_k127_5316467_2 Histidine kinase - - - 0.00000000000000000005144 93.0
TLS3_k127_5337619_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1185.0
TLS3_k127_5337619_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.803e-204 661.0
TLS3_k127_5337619_10 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 308.0
TLS3_k127_5337619_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 287.0
TLS3_k127_5337619_12 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000002678 233.0
TLS3_k127_5337619_13 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000482 219.0
TLS3_k127_5337619_14 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000003712 199.0
TLS3_k127_5337619_15 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000000000000000000000000000005171 183.0
TLS3_k127_5337619_16 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000002279 184.0
TLS3_k127_5337619_17 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000006214 160.0
TLS3_k127_5337619_18 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001007 164.0
TLS3_k127_5337619_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 543.0
TLS3_k127_5337619_20 Response regulator, receiver - - - 0.00000000000000000000000000001407 132.0
TLS3_k127_5337619_21 PFAM Rubrerythrin - - - 0.00000000000000000007601 89.0
TLS3_k127_5337619_3 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 551.0
TLS3_k127_5337619_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 441.0
TLS3_k127_5337619_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 393.0
TLS3_k127_5337619_7 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 387.0
TLS3_k127_5337619_8 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 349.0
TLS3_k127_5337619_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 347.0
TLS3_k127_5373101_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.488e-219 693.0
TLS3_k127_5373101_1 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 606.0
TLS3_k127_5373101_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 448.0
TLS3_k127_5373101_3 Chemotaxis sensory transducer K03406,K13487 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 378.0
TLS3_k127_5373101_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000004792 141.0
TLS3_k127_5373101_5 DTW - - - 0.00000000000000000001003 102.0
TLS3_k127_5434876_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 1.086e-206 657.0
TLS3_k127_5434876_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 539.0
TLS3_k127_5434876_2 Bacterial extracellular solute-binding proteins, family 3 K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 476.0
TLS3_k127_5434876_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003479 270.0
TLS3_k127_5434876_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000003691 192.0
TLS3_k127_5434876_5 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000002901 121.0
TLS3_k127_5463917_0 helicase - - - 1.005e-242 760.0
TLS3_k127_5463917_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007919 270.0
TLS3_k127_5463944_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.319e-229 715.0
TLS3_k127_5463944_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 562.0
TLS3_k127_5463944_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 547.0
TLS3_k127_5463944_3 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000001948 220.0
TLS3_k127_5463944_4 negative regulation of translational initiation - - - 0.0000000000000000000000000000000000000000000000004817 180.0
TLS3_k127_5463944_5 - - - - 0.0000000004722 64.0
TLS3_k127_5483748_0 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 382.0
TLS3_k127_5483748_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000034 284.0
TLS3_k127_5483748_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000001569 190.0
TLS3_k127_5483748_3 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000002072 177.0
TLS3_k127_5511359_0 FAD linked oxidase domain protein - - - 0.0 1614.0
TLS3_k127_5511359_1 PFAM Major facilitator superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000001383 238.0
TLS3_k127_5511359_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0000000000000000000000000000000000000009926 156.0
TLS3_k127_5511359_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.00000000000000000000000000000000000001125 154.0
TLS3_k127_5573575_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 2.411e-282 884.0
TLS3_k127_5573575_1 Domain of unknown function (DUF4091) - - - 2.623e-213 677.0
TLS3_k127_5573575_10 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000002644 236.0
TLS3_k127_5573575_12 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000001483 185.0
TLS3_k127_5573575_13 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000001335 168.0
TLS3_k127_5573575_15 - - - - 0.000000000000000002047 94.0
TLS3_k127_5573575_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 567.0
TLS3_k127_5573575_3 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 495.0
TLS3_k127_5573575_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 465.0
TLS3_k127_5573575_5 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 400.0
TLS3_k127_5573575_6 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 348.0
TLS3_k127_5573575_7 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 342.0
TLS3_k127_5573575_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 291.0
TLS3_k127_5573575_9 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000003279 236.0
TLS3_k127_5623416_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 3.328e-273 843.0
TLS3_k127_5623416_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 4.625e-214 670.0
TLS3_k127_5623416_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 356.0
TLS3_k127_5623416_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 339.0
TLS3_k127_5623416_4 HD domain K07814 - - 0.000000000000001155 90.0
TLS3_k127_5623416_5 PBS lyase - - - 0.000002014 51.0
TLS3_k127_5628000_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.43e-322 1009.0
TLS3_k127_5628000_1 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 431.0
TLS3_k127_5628000_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 342.0
TLS3_k127_5628000_3 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 313.0
TLS3_k127_5628000_4 FMN_bind - - - 0.00000000000000000000000000000000000000000000000000000000000000196 231.0
TLS3_k127_5628000_5 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000006223 220.0
TLS3_k127_5628000_6 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000005937 196.0
TLS3_k127_5628000_8 - - - - 0.00000000000000000000000000000000000009346 151.0
TLS3_k127_5628701_0 Cysteine-rich domain K00113 - 1.1.5.3 9.48e-238 740.0
TLS3_k127_5628701_1 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 413.0
TLS3_k127_5628701_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 383.0
TLS3_k127_5628701_3 Pfam Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 308.0
TLS3_k127_5628701_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 277.0
TLS3_k127_5628701_5 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004509 256.0
TLS3_k127_5628701_6 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K21515 - 2.1.1.209 0.000000000000000000000000000000000000000000000000000000000002481 226.0
TLS3_k127_5628701_7 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000002375 221.0
TLS3_k127_5628701_8 Ferric uptake regulator family K09825 - - 0.000000000000000000000004471 112.0
TLS3_k127_5630500_0 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005039 295.0
TLS3_k127_5630500_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000002653 201.0
TLS3_k127_5630500_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000006283 189.0
TLS3_k127_5630500_3 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000002064 153.0
TLS3_k127_5630500_4 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000002125 130.0
TLS3_k127_5644575_0 Sugar (and other) transporter - - - 7.718e-319 981.0
TLS3_k127_5644575_1 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 361.0
TLS3_k127_5644575_2 PFAM Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 301.0
TLS3_k127_5644575_3 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 287.0
TLS3_k127_5644575_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000001037 255.0
TLS3_k127_5644575_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000002461 128.0
TLS3_k127_5644575_6 COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription - - - 0.000000000000000000000769 100.0
TLS3_k127_5644575_7 phosphorelay signal transduction system - - - 0.0000000000007519 73.0
TLS3_k127_5704163_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 445.0
TLS3_k127_5704163_1 decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 351.0
TLS3_k127_5704163_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
TLS3_k127_5704163_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000186 213.0
TLS3_k127_5704163_5 PFAM DoxX family protein - - - 0.000000000000000000000000000000000000001945 167.0
TLS3_k127_5704163_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000007888 138.0
TLS3_k127_5733891_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 1.64e-219 685.0
TLS3_k127_5733891_1 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 426.0
TLS3_k127_5733891_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 412.0
TLS3_k127_5733891_3 ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 302.0
TLS3_k127_5733891_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000002024 229.0
TLS3_k127_574828_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 336.0
TLS3_k127_574828_1 Histidine kinase K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000002171 209.0
TLS3_k127_574828_2 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000005208 162.0
TLS3_k127_574828_3 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.00000000000000000001009 98.0
TLS3_k127_5755093_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1560.0
TLS3_k127_5755093_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 2.363e-256 800.0
TLS3_k127_5755093_10 Universal stress protein - - - 0.000000000000000000000000000001397 133.0
TLS3_k127_5755093_2 COG1233 Phytoene dehydrogenase and related proteins - - - 1.644e-249 779.0
TLS3_k127_5755093_3 Major Facilitator Superfamily K08177 - - 3.041e-204 643.0
TLS3_k127_5755093_4 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 501.0
TLS3_k127_5755093_5 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 460.0
TLS3_k127_5755093_6 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 429.0
TLS3_k127_5755093_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 409.0
TLS3_k127_5755093_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 369.0
TLS3_k127_5755093_9 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000000000000000001281 137.0
TLS3_k127_5762224_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.02e-224 726.0
TLS3_k127_5762224_1 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 373.0
TLS3_k127_5762224_2 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 357.0
TLS3_k127_5762224_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005351 248.0
TLS3_k127_5762224_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000008286 222.0
TLS3_k127_5762224_6 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.000000000000004112 77.0
TLS3_k127_5762224_7 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.0000000000005972 70.0
TLS3_k127_5765126_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 1.179e-265 826.0
TLS3_k127_5765126_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 1.627e-237 741.0
TLS3_k127_5765126_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 6.439e-200 643.0
TLS3_k127_5765126_3 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 341.0
TLS3_k127_5765126_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 342.0
TLS3_k127_5765126_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 302.0
TLS3_k127_5765126_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 301.0
TLS3_k127_5788709_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 572.0
TLS3_k127_5788709_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000402 230.0
TLS3_k127_5788709_2 methylamine metabolic process K15977 - - 0.000000000000000000006285 93.0
TLS3_k127_5788709_3 Uncharacterised ArCR, COG2043 - - - 0.0000000000002116 70.0
TLS3_k127_5821104_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 2.381e-259 832.0
TLS3_k127_5821104_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 8.71e-209 668.0
TLS3_k127_5821104_10 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 309.0
TLS3_k127_5821104_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 314.0
TLS3_k127_5821104_12 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002994 273.0
TLS3_k127_5821104_13 cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000001055 231.0
TLS3_k127_5821104_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000006872 216.0
TLS3_k127_5821104_16 TonB C terminal K03832 - - 0.000000000000000000000000000000000002345 147.0
TLS3_k127_5821104_17 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000001061 133.0
TLS3_k127_5821104_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 590.0
TLS3_k127_5821104_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 583.0
TLS3_k127_5821104_4 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 570.0
TLS3_k127_5821104_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 544.0
TLS3_k127_5821104_6 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 476.0
TLS3_k127_5821104_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 451.0
TLS3_k127_5821104_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 370.0
TLS3_k127_5821104_9 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 336.0
TLS3_k127_5848585_0 Tetratricopeptide repeat - - - 6.905e-297 971.0
TLS3_k127_5848585_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 509.0
TLS3_k127_5848585_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006384 267.0
TLS3_k127_5848585_3 - - - - 0.000000000000000000000000000000000000000000000000000000007147 216.0
TLS3_k127_5848585_4 FHA domain - - - 0.000000000000000000000000000000000000000002774 165.0
TLS3_k127_5856739_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.094e-216 683.0
TLS3_k127_5856739_1 glutamate--cysteine ligase K01919 - 6.3.2.2 2.877e-209 659.0
TLS3_k127_5856739_2 Tetratricopeptide repeat - - - 0.000029 57.0
TLS3_k127_586121_0 Peptidase family M50 K11749 - - 9.934e-231 735.0
TLS3_k127_586121_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 4.963e-196 626.0
TLS3_k127_586121_10 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005114 262.0
TLS3_k127_586121_11 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000007369 263.0
TLS3_k127_586121_12 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003059 252.0
TLS3_k127_586121_13 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000001419 202.0
TLS3_k127_586121_15 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000133 205.0
TLS3_k127_586121_17 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000004485 158.0
TLS3_k127_586121_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 528.0
TLS3_k127_586121_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 428.0
TLS3_k127_586121_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 376.0
TLS3_k127_586121_5 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
TLS3_k127_586121_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 347.0
TLS3_k127_586121_7 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 347.0
TLS3_k127_586121_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 314.0
TLS3_k127_586121_9 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 310.0
TLS3_k127_5872890_0 7TM receptor with intracellular HD hydrolase K07037 - - 2.064e-244 782.0
TLS3_k127_5872890_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 576.0
TLS3_k127_5872890_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 541.0
TLS3_k127_5872890_3 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 437.0
TLS3_k127_5872890_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000001019 72.0
TLS3_k127_597105_0 Surface antigen - - - 1.843e-215 691.0
TLS3_k127_597105_1 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 477.0
TLS3_k127_597105_10 - - - - 0.000000000000000000000000000000000145 146.0
TLS3_k127_597105_2 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 381.0
TLS3_k127_597105_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 361.0
TLS3_k127_597105_4 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 349.0
TLS3_k127_597105_5 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 320.0
TLS3_k127_597105_6 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008281 268.0
TLS3_k127_597105_7 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000006851 226.0
TLS3_k127_597105_8 TonB C terminal K03646,K03832 - - 0.000000000000000000000000000000000000000000000002656 188.0
TLS3_k127_597105_9 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000000000000001429 187.0
TLS3_k127_6012078_0 Polysaccharide deacetylase K11931 - - 9.435e-312 967.0
TLS3_k127_6012078_1 ATPase family associated with various cellular activities (AAA) - - - 9.854e-219 709.0
TLS3_k127_6012078_2 PFAM Glycosyl transferase family 2 K00752,K11936 - 2.4.1.212 2.079e-215 674.0
TLS3_k127_6012078_3 General secretory system II, protein E domain protein K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 535.0
TLS3_k127_6012078_4 PFAM Acetyl-CoA hydrolase transferase K01067,K18118 - 2.8.3.18,3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 462.0
TLS3_k127_6012078_5 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 381.0
TLS3_k127_6012078_6 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002369 239.0
TLS3_k127_6012078_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000005417 186.0
TLS3_k127_6012078_8 PgaD-like protein K11937 - - 0.0000000000000000000000000000000000001988 146.0
TLS3_k127_6016417_0 ABC transporter, ATP-binding protein - - - 1.673e-254 791.0
TLS3_k127_6016417_1 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 471.0
TLS3_k127_6016417_10 Glycosyl transferase, family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 315.0
TLS3_k127_6016417_11 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000727 213.0
TLS3_k127_6016417_12 PBP superfamily domain K02040 - - 0.0000000000000000009715 85.0
TLS3_k127_6016417_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 455.0
TLS3_k127_6016417_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 417.0
TLS3_k127_6016417_4 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 413.0
TLS3_k127_6016417_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 407.0
TLS3_k127_6016417_6 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
TLS3_k127_6016417_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
TLS3_k127_6016417_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
TLS3_k127_6016417_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 290.0
TLS3_k127_6035201_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1350.0
TLS3_k127_6035201_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 9.284e-234 740.0
TLS3_k127_6035201_2 Patatin-like phospholipase - - - 1.496e-201 638.0
TLS3_k127_6035201_3 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 331.0
TLS3_k127_6035201_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000001341 190.0
TLS3_k127_6043403_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.17e-304 941.0
TLS3_k127_6043403_1 Transcriptional regulator - GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 470.0
TLS3_k127_6043403_10 acyl-coa-binding protein - - - 0.000000000000000000000000359 115.0
TLS3_k127_6043403_11 PFAM isochorismatase hydrolase K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.0001661 52.0
TLS3_k127_6043403_2 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 430.0
TLS3_k127_6043403_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 397.0
TLS3_k127_6043403_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 367.0
TLS3_k127_6043403_5 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 322.0
TLS3_k127_6043403_6 cytochrome c nitrite reductase K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001899 259.0
TLS3_k127_6043403_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000001052 202.0
TLS3_k127_6043403_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000005846 198.0
TLS3_k127_6043403_9 EamA-like transporter family K05786 - - 0.0000000000000000000000000000000000000000000001248 173.0
TLS3_k127_6046631_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.52e-272 846.0
TLS3_k127_6046631_1 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 595.0
TLS3_k127_6046631_10 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000000000000001299 151.0
TLS3_k127_6046631_11 Surface antigen - - - 0.00003332 56.0
TLS3_k127_6046631_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 536.0
TLS3_k127_6046631_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K00534 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 522.0
TLS3_k127_6046631_4 Bacterial regulatory protein, Fis family K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 526.0
TLS3_k127_6046631_5 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 354.0
TLS3_k127_6046631_6 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 362.0
TLS3_k127_6046631_7 His Kinase A (phosphoacceptor) domain K19661 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 366.0
TLS3_k127_6046631_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 342.0
TLS3_k127_6046631_9 PFAM Major facilitator superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000587 197.0
TLS3_k127_6066456_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 349.0
TLS3_k127_6066456_1 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000002285 188.0
TLS3_k127_6066456_2 VanZ like family - - - 0.00002534 52.0
TLS3_k127_6066456_4 cellulase activity - - - 0.0005579 50.0
TLS3_k127_6084547_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.807e-253 787.0
TLS3_k127_6084547_1 glutaminyl-tRNA K01886 - 6.1.1.18 1.982e-221 712.0
TLS3_k127_6084547_10 Glutamine amidotransferases class-II - - - 0.000007517 48.0
TLS3_k127_6084547_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 548.0
TLS3_k127_6084547_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 318.0
TLS3_k127_6084547_4 Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000432 287.0
TLS3_k127_6084547_5 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000191 164.0
TLS3_k127_6084547_6 protein import - - - 0.000000000000000000000000000000000001069 153.0
TLS3_k127_6084547_7 - - - - 0.00000000000000000000000000000000002421 140.0
TLS3_k127_6084547_8 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000004528 117.0
TLS3_k127_6084547_9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669 - - 0.0000000000000007542 91.0
TLS3_k127_6093866_0 transcription factor binding K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 377.0
TLS3_k127_6093866_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001718 238.0
TLS3_k127_6113911_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 1.066e-296 926.0
TLS3_k127_6113911_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 336.0
TLS3_k127_6113911_2 energy transducer activity K03832 - - 0.0000000000000000000000000000000000000000000001572 181.0
TLS3_k127_6128563_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 397.0
TLS3_k127_6128563_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 343.0
TLS3_k127_6128563_2 High confidence in function and specificity K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 334.0
TLS3_k127_6128563_3 Cysteine-rich secretory protein family - - - 0.00000000005309 71.0
TLS3_k127_6130039_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.218e-274 851.0
TLS3_k127_6130039_1 PFAM glycosyl transferase family 25 K07270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
TLS3_k127_6130039_2 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000179 248.0
TLS3_k127_6130039_3 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000001535 193.0
TLS3_k127_6130039_4 MerR HTH family regulatory protein - - - 0.0000000000000000000000000003105 117.0
TLS3_k127_6133726_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 468.0
TLS3_k127_6133726_1 Major royal jelly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 391.0
TLS3_k127_6133726_3 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000001362 241.0
TLS3_k127_6133726_4 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.0000000000000000000000000007728 124.0
TLS3_k127_6133726_5 transcriptional regulator - - - 0.000000007615 65.0
TLS3_k127_6135203_0 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 510.0
TLS3_k127_6135203_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000004317 212.0
TLS3_k127_6147903_0 Aldehyde dehydrogenase family K00129 - 1.2.1.5 8.397e-215 686.0
TLS3_k127_6147903_2 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000002605 242.0
TLS3_k127_6147903_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000001633 225.0
TLS3_k127_6147903_4 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000000000000000000000000000000000000000000000000000000007372 212.0
TLS3_k127_6147903_5 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000001928 188.0
TLS3_k127_6147903_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000002621 174.0
TLS3_k127_6147903_8 sequence-specific DNA binding - - - 0.00000000000000000000000001897 111.0
TLS3_k127_6147903_9 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.00000000000000000002712 92.0
TLS3_k127_6169414_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.062e-234 742.0
TLS3_k127_6169414_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 496.0
TLS3_k127_6169414_2 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002435 264.0
TLS3_k127_620668_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 516.0
TLS3_k127_620668_1 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 403.0
TLS3_k127_620668_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 332.0
TLS3_k127_6210381_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 340.0
TLS3_k127_6210381_1 metallopeptidase activity K06974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 302.0
TLS3_k127_6210381_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000009788 186.0
TLS3_k127_6210381_3 - - - - 0.00000000000000001755 83.0
TLS3_k127_6227337_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 6.675e-267 828.0
TLS3_k127_6227337_1 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 399.0
TLS3_k127_6227337_3 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000001282 70.0
TLS3_k127_6228632_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.87e-231 730.0
TLS3_k127_6228632_1 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000004806 228.0
TLS3_k127_6228632_2 YaeQ - - - 0.00000000000000000000000000000000000000000000002386 172.0
TLS3_k127_6228632_3 2 iron, 2 sulfur cluster binding - - - 0.0000000000000000000000001184 112.0
TLS3_k127_6233839_0 Di-haem cytochrome c peroxidase - - - 1.921e-305 951.0
TLS3_k127_6233839_1 Cation transport protein K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 565.0
TLS3_k127_6233839_10 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K07025 - - 0.00000000000000000001446 104.0
TLS3_k127_6233839_2 Alpha beta hydrolase K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 536.0
TLS3_k127_6233839_3 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 458.0
TLS3_k127_6233839_4 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 321.0
TLS3_k127_6233839_5 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000001338 174.0
TLS3_k127_6233839_6 MOSC domain - - - 0.000000000000000000000000000000000000000000004742 168.0
TLS3_k127_6233839_7 PilT protein domain protein - - - 0.00000000000000000000000000000000000000000001083 171.0
TLS3_k127_6233839_8 - - - - 0.0000000000000000000000006194 109.0
TLS3_k127_6233839_9 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000002061 109.0
TLS3_k127_6266380_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.763e-216 689.0
TLS3_k127_6266380_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 599.0
TLS3_k127_6266380_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 506.0
TLS3_k127_6266380_3 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 345.0
TLS3_k127_6266380_4 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000000000000000004643 193.0
TLS3_k127_6287232_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 4.858e-223 713.0
TLS3_k127_6287232_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.06e-196 627.0
TLS3_k127_6287232_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 478.0
TLS3_k127_6287232_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 470.0
TLS3_k127_6287232_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 342.0
TLS3_k127_6287232_5 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000007993 222.0
TLS3_k127_6287232_6 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000000000002994 208.0
TLS3_k127_6298331_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1443.0
TLS3_k127_6298331_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.759e-211 668.0
TLS3_k127_6298331_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001044 184.0
TLS3_k127_6298331_11 nuclear chromosome segregation - - - 0.000000000000000000000000000004305 138.0
TLS3_k127_6298331_14 cheY-homologous receiver domain - - - 0.000000000002561 75.0
TLS3_k127_6298331_15 ribosome binding - - - 0.0000000007864 63.0
TLS3_k127_6298331_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 528.0
TLS3_k127_6298331_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 475.0
TLS3_k127_6298331_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 453.0
TLS3_k127_6298331_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 437.0
TLS3_k127_6298331_6 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 435.0
TLS3_k127_6298331_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 419.0
TLS3_k127_6298331_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 371.0
TLS3_k127_6298331_9 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000002943 238.0
TLS3_k127_6344610_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 7.424e-269 835.0
TLS3_k127_6344610_1 RecQ zinc-binding K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 533.0
TLS3_k127_6344610_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 466.0
TLS3_k127_6344610_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 359.0
TLS3_k127_6344610_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 357.0
TLS3_k127_6344610_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000003033 214.0
TLS3_k127_6349248_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 475.0
TLS3_k127_6349248_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 366.0
TLS3_k127_6349248_2 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 347.0
TLS3_k127_6349248_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009622 254.0
TLS3_k127_6349248_4 -O-antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000001025 254.0
TLS3_k127_6349248_5 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.00004633 46.0
TLS3_k127_6351758_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 521.0
TLS3_k127_6351758_1 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 478.0
TLS3_k127_6351758_2 Sterol desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 310.0
TLS3_k127_6351758_3 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000004331 243.0
TLS3_k127_6351758_4 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000001355 218.0
TLS3_k127_6351758_5 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000005866 183.0
TLS3_k127_6351758_6 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000001031 143.0
TLS3_k127_6365933_0 UvrD-like helicase C-terminal domain - - - 2.322e-302 942.0
TLS3_k127_6365933_1 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 437.0
TLS3_k127_6365933_10 abc transporter atp-binding protein K01990 - - 0.00000000000000000000000000000004028 127.0
TLS3_k127_6365933_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 351.0
TLS3_k127_6365933_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 318.0
TLS3_k127_6365933_4 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002106 280.0
TLS3_k127_6365933_5 protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000001996 215.0
TLS3_k127_6365933_6 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000000000000000002583 206.0
TLS3_k127_6365933_7 chaperone-mediated protein folding K21007 - - 0.0000000000000000000000000000000000000000000000000000178 209.0
TLS3_k127_6365933_8 Protein of unknown function (DUF2470) K07226 - - 0.000000000000000000000000000000000003378 143.0
TLS3_k127_6365933_9 EamA-like transporter family - - - 0.00000000000000000000000000000000104 132.0
TLS3_k127_6418240_0 PrkA AAA domain K07180 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 580.0
TLS3_k127_6418240_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 443.0
TLS3_k127_6418240_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000000000002133 190.0
TLS3_k127_6423036_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 521.0
TLS3_k127_6423036_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 355.0
TLS3_k127_6423036_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 289.0
TLS3_k127_6423036_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002372 266.0
TLS3_k127_6423036_4 SpoVG K06412 GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - 0.00000000000000007564 86.0
TLS3_k127_6427641_0 Peptidase family M48 - - - 9.753e-200 636.0
TLS3_k127_6427641_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004011 276.0
TLS3_k127_6427641_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 243.0
TLS3_k127_6427641_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003859 176.0
TLS3_k127_6427641_4 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000000000001326 158.0
TLS3_k127_6427641_5 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005255 136.0
TLS3_k127_6427641_6 - - - - 0.00000000000002779 77.0
TLS3_k127_6439272_0 CoA-substrate-specific enzyme activase - - - 0.0 1765.0
TLS3_k127_6439272_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 321.0
TLS3_k127_6459230_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 589.0
TLS3_k127_6459230_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 604.0
TLS3_k127_6459230_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 584.0
TLS3_k127_6459230_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 592.0
TLS3_k127_6459230_4 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 411.0
TLS3_k127_6459230_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 404.0
TLS3_k127_6459230_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000001097 53.0
TLS3_k127_6510095_0 RNA polymerase recycling family C-terminal K03580 - - 0.0 1076.0
TLS3_k127_6510095_1 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 453.0
TLS3_k127_6510095_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001466 261.0
TLS3_k127_6510095_3 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000004005 177.0
TLS3_k127_6510095_4 CHRD domain - - - 0.00000000000000000000000000004675 124.0
TLS3_k127_6554942_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 507.0
TLS3_k127_6554942_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000009081 206.0
TLS3_k127_6554942_2 cobalamin binding K03496,K22491 - - 0.000000000000000000000000000000000000000000000000000004501 203.0
TLS3_k127_6554942_3 Membrane protein involved in cytochrome C biogenesis - - - 0.000000000000000000000000000000000000000000006263 181.0
TLS3_k127_6554942_4 PAS domain containing protein - - - 0.000000000000000000000000000000000000000006676 167.0
TLS3_k127_6554942_6 peptidyl-tyrosine sulfation - - - 0.000000000000000007039 95.0
TLS3_k127_6591297_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 6.288e-265 836.0
TLS3_k127_6591297_1 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 4.863e-229 715.0
TLS3_k127_6591297_10 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000006677 183.0
TLS3_k127_6591297_11 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000000007185 171.0
TLS3_k127_6591297_12 Protein of unknown function (DUF1643) - - - 0.000000000000000000000000000000000006306 147.0
TLS3_k127_6591297_13 Signal transduction histidine kinase K11711 - 2.7.13.3 0.00000000003867 75.0
TLS3_k127_6591297_14 Belongs to the amidase family K01426 - 3.5.1.4 0.00000001223 57.0
TLS3_k127_6591297_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 427.0
TLS3_k127_6591297_3 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 407.0
TLS3_k127_6591297_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 308.0
TLS3_k127_6591297_5 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 302.0
TLS3_k127_6591297_6 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 298.0
TLS3_k127_6591297_7 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 293.0
TLS3_k127_6591297_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001226 283.0
TLS3_k127_6591297_9 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000003118 236.0
TLS3_k127_6595612_0 FAD dependent oxidoreductase K07137 - - 1.368e-261 816.0
TLS3_k127_6595612_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.687e-207 651.0
TLS3_k127_6595612_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 572.0
TLS3_k127_6595612_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 362.0
TLS3_k127_6595612_4 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000000000000002444 201.0
TLS3_k127_6595612_5 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000002097 107.0
TLS3_k127_6595612_7 Sporulation related domain - - - 0.0000000000008395 75.0
TLS3_k127_6622049_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 584.0
TLS3_k127_6622049_1 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 317.0
TLS3_k127_6622049_2 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000000004004 217.0
TLS3_k127_6622049_3 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.0000000000000000000000000000000000000000000000000000000006948 209.0
TLS3_k127_6622049_4 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000001006 147.0
TLS3_k127_6622049_5 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000188 149.0
TLS3_k127_6622049_6 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000003179 125.0
TLS3_k127_6641936_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2487.0
TLS3_k127_6641936_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 2.049e-266 826.0
TLS3_k127_6641936_2 ATP dependent DNA ligase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 349.0
TLS3_k127_6641936_3 DNA integration - - - 0.0000000000000000000000000000008392 127.0
TLS3_k127_6641936_4 Extracellular solute-binding protein family 3 K07679 - 2.7.13.3 0.0000000000000000000004686 113.0
TLS3_k127_6641936_5 COG0582 Integrase - - - 0.0005787 45.0
TLS3_k127_6669746_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.207e-202 639.0
TLS3_k127_6669746_1 HD domain K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000005096 185.0
TLS3_k127_6669746_2 alpha beta - - - 0.000000000000000000000000000000000000000000009125 169.0
TLS3_k127_6669746_4 hyaluronan metabolic process K19014 GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0043167,GO:0043169,GO:0046872 - 0.0000000000000000000000000003046 132.0
TLS3_k127_6669746_5 - - - - 0.00000000000000000000000005784 113.0
TLS3_k127_6676321_0 DNA helicase K03657 - 3.6.4.12 0.0 1026.0
TLS3_k127_6676321_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 4.151e-245 774.0
TLS3_k127_6676321_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 574.0
TLS3_k127_6676321_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 531.0
TLS3_k127_6676321_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 380.0
TLS3_k127_6676321_5 Histidine kinase K07711,K19694 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 366.0
TLS3_k127_6676321_6 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 248.0
TLS3_k127_6676321_7 Belongs to the Dps family - - - 0.0000000000000000000000000000000000000000000000000000004199 207.0
TLS3_k127_6676321_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000002286 179.0
TLS3_k127_6683627_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.0 1280.0
TLS3_k127_6683627_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 416.0
TLS3_k127_6683627_3 - - - - 0.00000000000000000000000000000000000001288 150.0
TLS3_k127_6683627_4 FMN binding - - - 0.00000000000000000000000000000000000009528 150.0
TLS3_k127_6683627_5 transcriptional regulator - - - 0.000000000000005759 76.0
TLS3_k127_6701247_0 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 369.0
TLS3_k127_6701247_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 308.0
TLS3_k127_6701247_2 Dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008658 282.0
TLS3_k127_6701247_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004507 269.0
TLS3_k127_6701247_4 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009583 269.0
TLS3_k127_6701247_5 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
TLS3_k127_6701247_6 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000006196 229.0
TLS3_k127_6701247_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000001898 208.0
TLS3_k127_6701247_8 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000000000001238 183.0
TLS3_k127_6701247_9 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000001881 198.0
TLS3_k127_6723375_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 338.0
TLS3_k127_6723375_1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000001807 147.0
TLS3_k127_6723375_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000003157 130.0
TLS3_k127_6837877_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.585e-275 905.0
TLS3_k127_6837877_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 3.298e-250 814.0
TLS3_k127_6837877_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 3.184e-195 619.0
TLS3_k127_6837877_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 393.0
TLS3_k127_6837877_4 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 351.0
TLS3_k127_6837877_5 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000005706 192.0
TLS3_k127_6837877_6 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001407 193.0
TLS3_k127_6881857_0 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 449.0
TLS3_k127_6881857_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003738 263.0
TLS3_k127_6881857_10 Ion transport protein K10716 - - 0.00000000000000000000164 109.0
TLS3_k127_6881857_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003143 233.0
TLS3_k127_6881857_3 - - - - 0.00000000000000000000000000000000000000000000000000000000005557 211.0
TLS3_k127_6881857_4 acid phosphatase activity K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000005458 215.0
TLS3_k127_6881857_5 - - - - 0.000000000000000000000000000000000000000000000000000003104 212.0
TLS3_k127_6881857_6 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000007051 158.0
TLS3_k127_6881857_7 YaeQ - - - 0.0000000000000000000000000000000009928 132.0
TLS3_k127_6881857_8 - - - - 0.000000000000000000000000000000005082 138.0
TLS3_k127_6881857_9 - - - - 0.0000000000000000000000009205 108.0
TLS3_k127_6912890_0 ERAP1-like C-terminal domain - - - 1.064e-240 772.0
TLS3_k127_6912890_1 glutaminyl-tRNA K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 330.0
TLS3_k127_6912890_2 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002559 278.0
TLS3_k127_6922045_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 5.29e-243 756.0
TLS3_k127_6922045_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 8.549e-232 736.0
TLS3_k127_6922045_10 cytochrome c K15876 - - 0.0000000000000000000000000000000000000000000000002494 183.0
TLS3_k127_6922045_11 Gaf domain - - - 0.00000000000000000000000000000001193 136.0
TLS3_k127_6922045_2 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 9.65e-211 687.0
TLS3_k127_6922045_3 AbgT putative transporter family K12942 - - 1.175e-209 663.0
TLS3_k127_6922045_4 Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 617.0
TLS3_k127_6922045_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 538.0
TLS3_k127_6922045_6 Histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 497.0
TLS3_k127_6922045_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 505.0
TLS3_k127_6922045_8 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 428.0
TLS3_k127_6922045_9 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000001047 207.0
TLS3_k127_693183_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 8.966e-300 930.0
TLS3_k127_693183_1 Pfam:Methyltransf_26 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 327.0
TLS3_k127_693183_2 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000473 235.0
TLS3_k127_693183_3 Glycosyl transferase, family 2 - - - 0.000000000000000000001045 107.0
TLS3_k127_6952756_0 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 599.0
TLS3_k127_6952756_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 366.0
TLS3_k127_6952756_2 - - - - 0.000000000000000000000003958 107.0
TLS3_k127_6952756_3 Histidine kinase - - - 0.000000000000000002692 94.0
TLS3_k127_6975118_0 Prolyl oligopeptidase family - - - 5.388e-257 809.0
TLS3_k127_6975118_1 Rod shape-determining protein K03569 - - 1.546e-203 640.0
TLS3_k127_6975118_2 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 599.0
TLS3_k127_6975118_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001583 243.0
TLS3_k127_6975118_4 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000576 219.0
TLS3_k127_6975118_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000003256 177.0
TLS3_k127_6985522_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1054.0
TLS3_k127_6985522_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.983e-220 689.0
TLS3_k127_6985522_2 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 546.0
TLS3_k127_6985522_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 510.0
TLS3_k127_6985522_4 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 480.0
TLS3_k127_6985522_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000001735 243.0
TLS3_k127_6985522_6 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000483 179.0
TLS3_k127_6993279_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 4.421e-283 893.0
TLS3_k127_6993279_1 DnaJ C terminal domain K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 483.0
TLS3_k127_6993279_2 PFAM Acetyl-CoA hydrolase transferase K01067,K18118 - 2.8.3.18,3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 330.0
TLS3_k127_6993279_3 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 319.0
TLS3_k127_6993279_4 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000001082 190.0
TLS3_k127_7053258_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 9.676e-215 676.0
TLS3_k127_7053258_1 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 572.0
TLS3_k127_7053258_10 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 311.0
TLS3_k127_7053258_11 transcriptional regulator K09017,K18301 - - 0.000000000000000000000000000000000000000000000000000000000000000000008089 240.0
TLS3_k127_7053258_12 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000001577 238.0
TLS3_k127_7053258_13 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.000000000000000000000000000000000008385 136.0
TLS3_k127_7053258_2 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 537.0
TLS3_k127_7053258_3 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 532.0
TLS3_k127_7053258_4 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 531.0
TLS3_k127_7053258_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 515.0
TLS3_k127_7053258_6 NAD+ binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 371.0
TLS3_k127_7053258_7 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 373.0
TLS3_k127_7053258_8 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 359.0
TLS3_k127_7053258_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 360.0
TLS3_k127_7064972_0 Response regulator receiver - - - 4.047e-267 827.0
TLS3_k127_7064972_1 Histidine kinase A domain protein K02482 - 2.7.13.3 3.019e-198 632.0
TLS3_k127_7064972_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 447.0
TLS3_k127_7064972_3 Belongs to the D-alanine--D-alanine ligase family - - - 0.0000000000000000000000000007405 114.0
TLS3_k127_7089610_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 529.0
TLS3_k127_7089610_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 413.0
TLS3_k127_7089610_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 397.0
TLS3_k127_7089610_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 375.0
TLS3_k127_7089610_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 377.0
TLS3_k127_7089610_6 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000000002118 182.0
TLS3_k127_7182716_0 Tetratricopeptide repeats - - - 6.739e-202 654.0
TLS3_k127_7182716_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.0000000000000000000000000000000000000000000000000000003518 196.0
TLS3_k127_7182716_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000003064 166.0
TLS3_k127_7191971_0 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 544.0
TLS3_k127_7191971_1 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 351.0
TLS3_k127_7191971_2 sequence-specific DNA binding - - - 0.000000000000000000000009884 110.0
TLS3_k127_7195760_0 Protein of unknown function, DUF255 K06888 - - 2.066e-309 964.0
TLS3_k127_7195760_1 Belongs to the RtcB family K14415 - 6.5.1.3 1.837e-245 764.0
TLS3_k127_7195760_2 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 545.0
TLS3_k127_7195760_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 493.0
TLS3_k127_7195760_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000001153 237.0
TLS3_k127_7195760_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000003798 187.0
TLS3_k127_7195760_6 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000005526 138.0
TLS3_k127_7195760_7 PAS fold - - - 0.00000000000000000000000000000004075 131.0
TLS3_k127_7195760_8 - - - - 0.0000000000000000001437 104.0
TLS3_k127_7195760_9 CsbD-like - - - 0.00055 46.0
TLS3_k127_7197207_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1405.0
TLS3_k127_7197207_1 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 320.0
TLS3_k127_7197207_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000006385 277.0
TLS3_k127_7197207_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000004479 249.0
TLS3_k127_7197207_5 FtsX-like permease family - - - 0.000000000000000000000000000000007261 131.0
TLS3_k127_7255982_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 577.0
TLS3_k127_7255982_1 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 569.0
TLS3_k127_7255982_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 531.0
TLS3_k127_7255982_3 response regulator K07685 - - 0.00000000000000000000000000000000000000000000000000000000000005541 235.0
TLS3_k127_7255982_4 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000001408 190.0
TLS3_k127_7255982_5 Domain of unknown function (DUF4388) - - - 0.0002127 46.0
TLS3_k127_7266566_0 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 552.0
TLS3_k127_7266566_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 339.0
TLS3_k127_7266566_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001098 222.0
TLS3_k127_7266566_3 ATP:ADP antiporter activity K01932,K03301 - - 0.000000000000000000000000000000000000000000000000000001469 208.0
TLS3_k127_7266566_4 ThiS family - - - 0.000000000000000000000000000000008364 140.0
TLS3_k127_7266566_5 polysaccharide biosynthetic process - - - 0.000003373 51.0
TLS3_k127_7267174_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 461.0
TLS3_k127_7267174_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 414.0
TLS3_k127_7267174_2 oxygen carrier activity K07216 - - 0.000000000000000000000000007299 116.0
TLS3_k127_7267174_3 - - - - 0.0000000000000000000002054 108.0
TLS3_k127_7267174_4 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000000215 83.0
TLS3_k127_7334873_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1150.0
TLS3_k127_7334873_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 1.305e-224 700.0
TLS3_k127_7334873_10 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000002507 163.0
TLS3_k127_7334873_11 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000000004595 139.0
TLS3_k127_7334873_12 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000006265 65.0
TLS3_k127_7334873_13 PEGA domain - - - 0.00000000005471 70.0
TLS3_k127_7334873_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 604.0
TLS3_k127_7334873_3 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 556.0
TLS3_k127_7334873_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 577.0
TLS3_k127_7334873_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 451.0
TLS3_k127_7334873_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 436.0
TLS3_k127_7334873_7 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003346 274.0
TLS3_k127_7334873_9 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000001249 173.0
TLS3_k127_7353703_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1412.0
TLS3_k127_7353703_1 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 1.424e-261 813.0
TLS3_k127_7353703_11 PFAM Outer membrane efflux protein - - - 0.00000000001916 77.0
TLS3_k127_7353703_2 Sigma-54 interaction domain K07713,K07714 - - 5.015e-199 654.0
TLS3_k127_7353703_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 563.0
TLS3_k127_7353703_4 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 437.0
TLS3_k127_7353703_5 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 394.0
TLS3_k127_7353703_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 344.0
TLS3_k127_7353703_7 Thioesterase superfamily K18014 - 4.3.1.14 0.00000000000000000000000000000000000000000000000000000000000002579 229.0
TLS3_k127_7353703_9 Belongs to the bacterial histone-like protein family K03530 - - 0.00000000000000000000000000000000002231 150.0
TLS3_k127_7357345_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 320.0
TLS3_k127_7357345_1 spore germination K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 323.0
TLS3_k127_7357345_2 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000001649 151.0
TLS3_k127_7357345_3 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000002247 113.0
TLS3_k127_7379548_0 Putative glutamine amidotransferase - - - 2.791e-287 913.0
TLS3_k127_7379548_1 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 1.628e-236 744.0
TLS3_k127_7379548_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 529.0
TLS3_k127_7379548_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 477.0
TLS3_k127_7379548_4 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 435.0
TLS3_k127_7379548_5 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 376.0
TLS3_k127_7379548_6 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 351.0
TLS3_k127_7379548_7 Iodothyronine deiodinase - - - 0.000000000000000000000000000000000000000000008231 173.0
TLS3_k127_7379548_8 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000001959 166.0
TLS3_k127_7379548_9 Ferredoxin - - - 0.0000000000000000000000000000000000000000007983 159.0
TLS3_k127_7389827_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1235.0
TLS3_k127_7389827_1 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 506.0
TLS3_k127_7389827_2 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 293.0
TLS3_k127_7389827_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000009059 125.0
TLS3_k127_7389827_4 DnaJ molecular chaperone homology domain - - - 0.0000644 49.0
TLS3_k127_7420806_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 420.0
TLS3_k127_7420806_1 amino acid ABC transporter, ATP-binding protein K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 374.0
TLS3_k127_7420806_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 341.0
TLS3_k127_7476859_0 Insulinase (Peptidase family M16) - - - 0.0 1052.0
TLS3_k127_7476859_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 507.0
TLS3_k127_7476859_2 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 467.0
TLS3_k127_7476859_3 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 427.0
TLS3_k127_7476859_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 335.0
TLS3_k127_7476859_5 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000000000000000001059 165.0
TLS3_k127_7476859_6 antisigma factor binding K02066,K02660,K04749,K04757,K05946,K06378 - 2.4.1.187,2.7.11.1 0.000000000000000000000000000004207 125.0
TLS3_k127_7476859_7 - - - - 0.000000000000000000000000604 116.0
TLS3_k127_7476859_8 Peptidoglycan-binding domain 1 protein - - - 0.000000000000001725 85.0
TLS3_k127_7478276_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 531.0
TLS3_k127_7478276_2 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 286.0
TLS3_k127_7478276_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006937 280.0
TLS3_k127_7478276_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000001145 242.0
TLS3_k127_7505732_0 AbgT putative transporter family K12942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 447.0
TLS3_k127_7505732_1 LrgB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 305.0
TLS3_k127_7505732_2 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000001925 174.0
TLS3_k127_7505732_3 LrgA family K06518 - - 0.00000000000000000000000000000000002134 142.0
TLS3_k127_7505732_4 TOBE domain - - - 0.0000000000000002962 82.0
TLS3_k127_7558722_0 Alpha-amylase domain K01176 - 3.2.1.1 9.756e-210 664.0
TLS3_k127_7558722_1 Bacterial extracellular solute-binding protein K10108,K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 591.0
TLS3_k127_7558722_2 Belongs to the ABC transporter superfamily K05816,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 512.0
TLS3_k127_7558722_3 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 398.0
TLS3_k127_7593546_0 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 1.799e-314 979.0
TLS3_k127_7593546_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000001037 218.0
TLS3_k127_7593546_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000001088 98.0
TLS3_k127_7593546_4 - - - - 0.000003302 57.0
TLS3_k127_7600443_0 Signal transduction histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 626.0
TLS3_k127_7600443_1 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 443.0
TLS3_k127_7600443_2 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 371.0
TLS3_k127_7600443_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 360.0
TLS3_k127_7600443_4 Domain of unknown function (DUF4912) K09942 - - 0.0000000000004653 76.0
TLS3_k127_7634892_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 428.0
TLS3_k127_7634892_1 Peptidase family M28 - - - 0.000000000000000000000000000000002947 147.0
TLS3_k127_7670737_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.086e-213 673.0
TLS3_k127_7670737_1 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 558.0
TLS3_k127_7670737_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 359.0
TLS3_k127_7670737_3 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 294.0
TLS3_k127_7670737_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000000001234 213.0
TLS3_k127_7670737_5 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000001871 59.0
TLS3_k127_7670737_7 - - - - 0.000008277 56.0
TLS3_k127_7697614_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0 1673.0
TLS3_k127_7697614_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 604.0
TLS3_k127_7697614_2 Belongs to the arginase family K01479,K12255 - 3.5.3.7,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 312.0
TLS3_k127_7697614_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000003038 216.0
TLS3_k127_7697614_4 4-Oxalocrotonate Tautomerase - - - 0.000000000000000000000000000000000000000000000001262 195.0
TLS3_k127_7697614_5 Sigma-54 interaction domain K07713,K07714 - - 0.00000000000000000000000000004846 127.0
TLS3_k127_7697614_6 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000001523 103.0
TLS3_k127_7697614_7 Histidine kinase - - - 0.00000000000000000001541 93.0
TLS3_k127_7750732_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 3.221e-242 765.0
TLS3_k127_7750732_1 Insulinase (Peptidase family M16) - - - 2.552e-201 635.0
TLS3_k127_7750732_2 Cys Met metabolism K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 556.0
TLS3_k127_7750732_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000008824 252.0
TLS3_k127_7750732_4 sequence-specific DNA binding - - - 0.000000000000000000000000001247 114.0
TLS3_k127_7768658_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1142.0
TLS3_k127_7768658_1 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 358.0
TLS3_k127_7768658_2 STAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 333.0
TLS3_k127_7768658_3 PFAM CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 324.0
TLS3_k127_7768658_4 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.0000000000000000000000000000000000000000000000002022 179.0
TLS3_k127_7768658_5 Stage II sporulation protein E K05518 - 3.1.3.3 0.000000000000000000000000000000000000000000000183 178.0
TLS3_k127_7768658_6 PFAM Sulfate transporter antisigma-factor antagonist STAS K17762 - - 0.000000000000000000000000000000000000000151 156.0
TLS3_k127_7768658_7 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000001106 144.0
TLS3_k127_7775928_0 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 483.0
TLS3_k127_7775928_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 356.0
TLS3_k127_7775928_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000004522 171.0
TLS3_k127_7775928_3 metal-dependent membrane protease K07052 - - 0.00000005759 63.0
TLS3_k127_7775928_4 Peptidase dimerisation domain K01436 - - 0.0000009651 52.0
TLS3_k127_7807181_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.042e-206 650.0
TLS3_k127_7807181_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 566.0
TLS3_k127_7807181_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001319 288.0
TLS3_k127_7807181_11 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000001846 206.0
TLS3_k127_7807181_2 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 556.0
TLS3_k127_7807181_3 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 544.0
TLS3_k127_7807181_4 Male sterility protein K12454 - 5.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 496.0
TLS3_k127_7807181_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 484.0
TLS3_k127_7807181_6 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 427.0
TLS3_k127_7807181_7 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 392.0
TLS3_k127_7807181_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 374.0
TLS3_k127_7807181_9 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 347.0
TLS3_k127_7811051_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 485.0
TLS3_k127_7811051_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 446.0
TLS3_k127_7811051_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 392.0
TLS3_k127_7811051_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21564 - - 0.0000000000000000000001056 111.0
TLS3_k127_7815215_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 3.239e-274 871.0
TLS3_k127_7815215_1 Maltogenic Amylase, C-terminal domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 1.502e-228 726.0
TLS3_k127_7815215_10 COG0530 Ca2 Na antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000001334 233.0
TLS3_k127_7815215_11 - - - - 0.0000000000000000000000000000000001752 149.0
TLS3_k127_7815215_12 - - - - 0.00000000489 63.0
TLS3_k127_7815215_2 PTS system, fructose-specific K02769,K02770 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090582 2.7.1.202 5.845e-198 632.0
TLS3_k127_7815215_3 Cytochrome C and Quinol oxidase polypeptide I K15408 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 466.0
TLS3_k127_7815215_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 392.0
TLS3_k127_7815215_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 355.0
TLS3_k127_7815215_6 Belongs to the carbohydrate kinase PfkB family K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000681 296.0
TLS3_k127_7815215_7 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001933 273.0
TLS3_k127_7815215_8 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351 - - 0.0000000000000000000000000000000000000000000000000000000000000000002832 241.0
TLS3_k127_7815215_9 LamB porin K02024 - - 0.0000000000000000000000000000000000000000000000000000000000000000008539 244.0
TLS3_k127_7836723_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.0 1112.0
TLS3_k127_7836723_1 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 570.0
TLS3_k127_7836723_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 522.0
TLS3_k127_7836723_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 466.0
TLS3_k127_7836723_4 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 357.0
TLS3_k127_7836723_7 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000002677 139.0
TLS3_k127_784364_0 membrane organization - - - 0.0 1102.0
TLS3_k127_784364_1 Belongs to the DegT DnrJ EryC1 family K19430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 615.0
TLS3_k127_784364_2 - - - - 0.0000000000000000000000000000000000004726 156.0
TLS3_k127_784364_3 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000001072 148.0
TLS3_k127_784364_4 cellulose binding K01183,K01233,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.132,3.2.1.14,3.2.1.17 0.00000000000000000000008739 112.0
TLS3_k127_784364_5 TLC ATP/ADP transporter - - - 0.00000000006243 75.0
TLS3_k127_7872936_0 4Fe-4S dicluster domain K18930 - - 0.0 1318.0
TLS3_k127_7872936_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 449.0
TLS3_k127_7872936_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000909 241.0
TLS3_k127_7872936_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000003055 203.0
TLS3_k127_7872936_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000001316 104.0
TLS3_k127_7872936_5 CoA-binding protein K06929 - - 0.0000000000000004458 84.0
TLS3_k127_7872936_6 Transcriptional regulatory protein, C terminal - - - 0.000004287 61.0
TLS3_k127_7872936_7 - - - - 0.00006179 51.0
TLS3_k127_7873027_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 1.591e-207 649.0
TLS3_k127_7873027_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 518.0
TLS3_k127_7873027_10 MerR, DNA binding K19591 - - 0.00000000000000000000000000000000000000000000000000000000001218 214.0
TLS3_k127_7873027_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000003371 152.0
TLS3_k127_7873027_12 - - - - 0.000000000000000000000000001638 127.0
TLS3_k127_7873027_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 512.0
TLS3_k127_7873027_3 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 470.0
TLS3_k127_7873027_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 433.0
TLS3_k127_7873027_5 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 417.0
TLS3_k127_7873027_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 397.0
TLS3_k127_7873027_7 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 392.0
TLS3_k127_7873027_8 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 376.0
TLS3_k127_7873027_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 368.0
TLS3_k127_7882970_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1069.0
TLS3_k127_7882970_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 7.751e-250 792.0
TLS3_k127_7882970_10 Homocysteine S-methyltransferase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.000000000000000000000411 99.0
TLS3_k127_7882970_2 ammonium transporter K03320 - - 1.936e-236 766.0
TLS3_k127_7882970_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 526.0
TLS3_k127_7882970_4 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 448.0
TLS3_k127_7882970_5 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 404.0
TLS3_k127_7882970_6 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 382.0
TLS3_k127_7882970_7 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000002477 219.0
TLS3_k127_7882970_8 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000005262 171.0
TLS3_k127_7882970_9 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000003992 162.0
TLS3_k127_7889851_0 Transporter K03305 - - 1.785e-257 802.0
TLS3_k127_7889851_1 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 601.0
TLS3_k127_7889851_10 intradiol ring-cleavage dioxygenase - - - 0.000000000000000000000000000000000000000000002818 185.0
TLS3_k127_7889851_12 Major facilitator Superfamily - - - 0.000000000000006999 78.0
TLS3_k127_7889851_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 539.0
TLS3_k127_7889851_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 505.0
TLS3_k127_7889851_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 458.0
TLS3_k127_7889851_5 RmlD substrate binding domain K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 419.0
TLS3_k127_7889851_6 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 359.0
TLS3_k127_7889851_7 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 360.0
TLS3_k127_7889851_8 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 325.0
TLS3_k127_7889851_9 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001266 244.0
TLS3_k127_7895515_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 615.0
TLS3_k127_7895515_1 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 556.0
TLS3_k127_7895515_10 Bacteriophage replication gene A protein (GPA) - - - 0.000000000001644 73.0
TLS3_k127_7895515_2 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 348.0
TLS3_k127_7895515_3 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 332.0
TLS3_k127_7895515_4 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 296.0
TLS3_k127_7895515_5 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 297.0
TLS3_k127_7895515_6 HemY protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008166 257.0
TLS3_k127_7895515_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000002201 198.0
TLS3_k127_7895515_8 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000152 164.0
TLS3_k127_7918944_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 394.0
TLS3_k127_7918944_1 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 366.0
TLS3_k127_7918944_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000002422 203.0
TLS3_k127_7918944_3 Putative diguanylate phosphodiesterase K03320 - - 0.0000000000000000000000001102 124.0
TLS3_k127_7918944_4 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000001074 91.0
TLS3_k127_7918944_5 GYD domain - - - 0.0000000000000000001047 93.0
TLS3_k127_7918944_6 - - - - 0.0000000000001456 75.0
TLS3_k127_7918944_7 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000023 74.0
TLS3_k127_7930007_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.933e-286 889.0
TLS3_k127_7930007_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.815e-218 700.0
TLS3_k127_7930007_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001645 272.0
TLS3_k127_7930007_3 MASE1 - - - 0.000000000000000000000000000000000000000003053 164.0
TLS3_k127_7930007_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000002365 136.0
TLS3_k127_7936295_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 445.0
TLS3_k127_7936295_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 433.0
TLS3_k127_7936295_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 386.0
TLS3_k127_7936295_3 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 332.0
TLS3_k127_7936295_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 311.0
TLS3_k127_7936295_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 302.0
TLS3_k127_7936295_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000007248 259.0
TLS3_k127_7936295_7 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000003961 103.0
TLS3_k127_7936295_8 DUF1704 - - - 0.00000000000000000007141 89.0
TLS3_k127_7936295_9 Phosphoribosyl-ATP pyrophosphatase K01523 - 3.6.1.31 0.0000000006271 65.0
TLS3_k127_7957157_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 5.42e-237 743.0
TLS3_k127_7957157_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 6.996e-220 689.0
TLS3_k127_7957157_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 2.943e-194 611.0
TLS3_k127_7957157_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 473.0
TLS3_k127_7957157_4 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001613 267.0
TLS3_k127_7957157_6 lipopolysaccharide transport K04744 - - 0.000000000000000000000000555 109.0
TLS3_k127_7989579_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.037e-281 875.0
TLS3_k127_7989579_1 PFAM PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 327.0
TLS3_k127_7989579_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000001068 192.0
TLS3_k127_7989579_5 Small hydrophilic plant seed protein - - - 0.00000000000000002356 83.0
TLS3_k127_8025103_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.521e-281 876.0
TLS3_k127_8025103_1 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 3.148e-198 632.0
TLS3_k127_8025103_2 Methyl-transferase K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 547.0
TLS3_k127_8025103_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 493.0
TLS3_k127_8045431_0 oligopeptide transporter - - - 2.868e-200 656.0
TLS3_k127_8045431_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 278.0
TLS3_k127_8045431_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000002857 235.0
TLS3_k127_8076486_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1447.0
TLS3_k127_8076486_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.728e-254 798.0
TLS3_k127_8076486_10 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 299.0
TLS3_k127_8076486_11 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001052 292.0
TLS3_k127_8076486_12 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000000828 248.0
TLS3_k127_8076486_13 ABC transporter, ATP-binding protein - - - 0.00000000000000000000000000000000000001568 145.0
TLS3_k127_8076486_14 cheY-homologous receiver domain - - - 0.000000000000000000000000000001638 126.0
TLS3_k127_8076486_15 - - - - 0.000000000000000000002743 101.0
TLS3_k127_8076486_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.151e-242 771.0
TLS3_k127_8076486_3 Cytochrome c bacterial - - - 1.555e-224 710.0
TLS3_k127_8076486_4 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 612.0
TLS3_k127_8076486_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 497.0
TLS3_k127_8076486_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 452.0
TLS3_k127_8076486_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 417.0
TLS3_k127_8076486_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 387.0
TLS3_k127_8076486_9 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 307.0
TLS3_k127_8112201_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 452.0
TLS3_k127_8112201_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 292.0
TLS3_k127_8112201_2 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001693 239.0
TLS3_k127_8112201_3 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000001846 91.0
TLS3_k127_8112201_4 zinc-ribbon domain - - - 0.00003142 56.0
TLS3_k127_8119124_0 Selenocysteine-specific translation elongation factor K03833 - - 2.778e-293 927.0
TLS3_k127_8119124_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 499.0
TLS3_k127_8119124_2 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 427.0
TLS3_k127_8119124_3 Hsp33 protein K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 392.0
TLS3_k127_8119124_4 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 391.0
TLS3_k127_8119124_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 391.0
TLS3_k127_8119124_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 291.0
TLS3_k127_8119124_7 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000007163 163.0
TLS3_k127_8119943_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.879e-264 815.0
TLS3_k127_8119943_1 response regulator K07713 - - 3.933e-217 681.0
TLS3_k127_8119943_2 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 366.0
TLS3_k127_8119943_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000000008667 156.0
TLS3_k127_8134845_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.447e-272 844.0
TLS3_k127_8134845_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 1.975e-215 676.0
TLS3_k127_8134845_11 SMART Rhodanese domain protein - - - 0.00007828 46.0
TLS3_k127_8134845_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0004277 49.0
TLS3_k127_8134845_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 505.0
TLS3_k127_8134845_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 481.0
TLS3_k127_8134845_4 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 412.0
TLS3_k127_8134845_5 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 359.0
TLS3_k127_8134845_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 370.0
TLS3_k127_8134845_7 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 321.0
TLS3_k127_8134845_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004015 291.0
TLS3_k127_8134845_9 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000004543 168.0
TLS3_k127_8144840_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.472e-301 931.0
TLS3_k127_8144840_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.352e-270 836.0
TLS3_k127_8144840_10 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000005254 136.0
TLS3_k127_8144840_11 - - - - 0.0000000000000001547 94.0
TLS3_k127_8144840_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.122e-217 682.0
TLS3_k127_8144840_3 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 531.0
TLS3_k127_8144840_4 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 456.0
TLS3_k127_8144840_6 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 400.0
TLS3_k127_8144840_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 314.0
TLS3_k127_8144840_8 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 310.0
TLS3_k127_8144840_9 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 239.0
TLS3_k127_8147231_0 - - - - 2.145e-226 721.0
TLS3_k127_8147231_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000005145 228.0
TLS3_k127_8159810_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1128.0
TLS3_k127_8159810_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 2.301e-248 785.0
TLS3_k127_8159810_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 459.0
TLS3_k127_8159810_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 459.0
TLS3_k127_8159810_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 418.0
TLS3_k127_8159810_5 Membrane protein, TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 363.0
TLS3_k127_8159810_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 327.0
TLS3_k127_8159810_7 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 307.0
TLS3_k127_8159810_8 Ubiquinol-cytochrome C reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002613 232.0
TLS3_k127_8159810_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.0000000000000000000000001871 109.0
TLS3_k127_8187163_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.147e-317 978.0
TLS3_k127_8187163_1 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 305.0
TLS3_k127_8187163_2 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000005452 235.0
TLS3_k127_8259482_0 Heat shock 70 kDa protein - - - 1.951e-252 800.0
TLS3_k127_8259482_1 synthase K01858 - 5.5.1.4 6.833e-238 744.0
TLS3_k127_8259482_2 domain protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 305.0
TLS3_k127_8259482_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000007586 203.0
TLS3_k127_8259482_4 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.00000000000000000000000000000000000000000241 170.0
TLS3_k127_8259482_5 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000001018 121.0
TLS3_k127_8259482_6 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000002571 93.0
TLS3_k127_8272693_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1162.0
TLS3_k127_8272693_1 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000003471 181.0
TLS3_k127_8272693_2 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K05586 - 1.6.5.3 0.0000000000000000005815 104.0
TLS3_k127_8273769_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1251.0
TLS3_k127_8273769_1 PFAM ThiJ PfpI domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 326.0
TLS3_k127_8273769_2 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000004258 123.0
TLS3_k127_8273769_3 Class III cytochrome C family - - - 0.000000000000000000000000009053 113.0
TLS3_k127_8273769_4 peptidase, M16 K07263,K07623 - - 0.000000000000000000000003106 103.0
TLS3_k127_8305829_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 4.244e-244 773.0
TLS3_k127_8305829_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.045e-219 686.0
TLS3_k127_8305829_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000005648 218.0
TLS3_k127_8314161_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 1.449e-202 638.0
TLS3_k127_8314161_1 Peptidase, M61 - - - 4.046e-198 628.0
TLS3_k127_8314161_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 403.0
TLS3_k127_832384_0 Signal transduction histidine kinase - - - 5e-324 1006.0
TLS3_k127_832384_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 512.0
TLS3_k127_832384_2 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000002492 120.0
TLS3_k127_8326036_0 penicillin-binding protein K03587 - 3.4.16.4 1.292e-204 664.0
TLS3_k127_8326036_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 471.0
TLS3_k127_8326036_2 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 389.0
TLS3_k127_8326036_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 300.0
TLS3_k127_8326036_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000008412 179.0
TLS3_k127_8326036_6 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.000000000006872 78.0
TLS3_k127_832720_0 FtsX-like permease family - - - 5.267e-262 838.0
TLS3_k127_832720_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 360.0
TLS3_k127_832720_2 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 344.0
TLS3_k127_832720_3 Smr domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 293.0
TLS3_k127_832720_4 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001512 279.0
TLS3_k127_832720_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000004495 183.0
TLS3_k127_832720_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000001534 150.0
TLS3_k127_8331288_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1171.0
TLS3_k127_8331288_1 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 531.0
TLS3_k127_8331288_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 452.0
TLS3_k127_8331288_3 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 386.0
TLS3_k127_8331288_4 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 345.0
TLS3_k127_8331288_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002769 291.0
TLS3_k127_8331288_6 transglycosylase K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000202 248.0
TLS3_k127_8331288_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000004082 136.0
TLS3_k127_8331288_9 bacterial-type flagellum organization K02411,K03223 - - 0.000000006188 65.0
TLS3_k127_8334017_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1263.0
TLS3_k127_8334017_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 2.177e-218 695.0
TLS3_k127_8334017_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000006658 206.0
TLS3_k127_83668_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1784.0
TLS3_k127_83668_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1122.0
TLS3_k127_83668_10 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000654 264.0
TLS3_k127_83668_11 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005756 257.0
TLS3_k127_83668_12 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000677 237.0
TLS3_k127_83668_13 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000007409 247.0
TLS3_k127_83668_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000001039 238.0
TLS3_k127_83668_17 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000002292 215.0
TLS3_k127_83668_18 Glycine cleavage system regulatory protein - - - 0.0000000000000000000000000000000000000000000001614 173.0
TLS3_k127_83668_19 Cytochrome c - - - 0.00000000000000000000000000000000000002592 161.0
TLS3_k127_83668_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 2.358e-225 720.0
TLS3_k127_83668_23 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000000001212 84.0
TLS3_k127_83668_25 Lysyl oxidase - - - 0.0000000002575 71.0
TLS3_k127_83668_3 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 611.0
TLS3_k127_83668_4 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 409.0
TLS3_k127_83668_5 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 411.0
TLS3_k127_83668_6 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 398.0
TLS3_k127_83668_7 desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 404.0
TLS3_k127_83668_8 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 335.0
TLS3_k127_83668_9 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 298.0
TLS3_k127_8378241_0 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 518.0
TLS3_k127_8378241_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 498.0
TLS3_k127_8378241_2 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 421.0
TLS3_k127_8378241_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000003269 179.0
TLS3_k127_8378241_4 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000001081 143.0
TLS3_k127_8423974_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 450.0
TLS3_k127_8423974_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 309.0
TLS3_k127_8423974_2 monooxygenase activity K06966 - 3.2.2.10 0.000000000000000003782 87.0
TLS3_k127_8423974_3 Two component transcriptional regulator, winged helix family K07774 - - 0.0004985 49.0
TLS3_k127_8499438_0 heat shock protein 70 K04043 - - 1.02e-261 835.0
TLS3_k127_8499438_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 604.0
TLS3_k127_8499438_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 482.0
TLS3_k127_8499438_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003522 272.0
TLS3_k127_8499438_4 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000001172 187.0
TLS3_k127_8499438_5 - - - - 0.000000000000000000000000000000000000000000000003413 199.0
TLS3_k127_8499438_6 YCII-related domain K09780 - - 0.0000000000000000000000000004521 130.0
TLS3_k127_858220_0 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 574.0
TLS3_k127_858220_1 TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 477.0
TLS3_k127_858220_2 PFAM Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003517 260.0
TLS3_k127_858220_3 protein tyrosine kinase activity K08253,K16554 - 2.7.10.2 0.0000000000000000000000000000000000000000000000000000000000000000000003884 244.0
TLS3_k127_858220_5 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000003246 119.0
TLS3_k127_866673_0 Stage II sporulation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 551.0
TLS3_k127_866673_1 Aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 380.0
TLS3_k127_866673_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 361.0
TLS3_k127_866673_4 Rhodanese Homology Domain - - - 0.00000000000000000000000009988 117.0
TLS3_k127_866673_5 PhoB family transcriptional regulator K02483 - - 0.000000000000000000006892 99.0
TLS3_k127_87089_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.068e-264 820.0
TLS3_k127_87089_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 1.728e-202 638.0
TLS3_k127_87089_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 473.0
TLS3_k127_87089_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000007834 192.0
TLS3_k127_87089_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000302 138.0
TLS3_k127_883660_0 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 528.0
TLS3_k127_883660_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 359.0
TLS3_k127_883660_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000001071 224.0
TLS3_k127_883660_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000008363 78.0
TLS3_k127_934736_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.684e-308 956.0
TLS3_k127_934736_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.56e-269 840.0
TLS3_k127_934736_11 Protein of unknown function (DUF1257) - - - 0.000002907 54.0
TLS3_k127_934736_13 Protein of unknown function (DUF2997) - - - 0.00005384 48.0
TLS3_k127_934736_2 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 1.783e-233 738.0
TLS3_k127_934736_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 433.0
TLS3_k127_934736_4 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 347.0
TLS3_k127_934736_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 284.0
TLS3_k127_934736_6 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000002859 250.0
TLS3_k127_934736_7 GGDEF domain K21009 - - 0.0000000000000000000000000000000000000000000000000000001078 207.0
TLS3_k127_934736_8 response regulator K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000004615 191.0
TLS3_k127_934736_9 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000002207 96.0
TLS3_k127_938333_0 PFAM lipopolysaccharide biosynthesis protein K16692 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 600.0
TLS3_k127_938333_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 410.0
TLS3_k127_938333_2 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 333.0
TLS3_k127_938333_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001836 250.0
TLS3_k127_938333_5 nucleoside diphosphate kinase K06140 - - 0.000000000000000000000000000000007892 135.0
TLS3_k127_938333_6 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000007136 111.0
TLS3_k127_938333_7 Acetyltransferase (GNAT) domain - - - 0.000001516 59.0
TLS3_k127_952556_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1691.0
TLS3_k127_952556_1 PFAM chemotaxis sensory transducer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 601.0
TLS3_k127_952556_2 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000001736 150.0
TLS3_k127_952556_3 - - - - 0.0000001319 53.0
TLS3_k127_988659_0 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 518.0
TLS3_k127_988659_1 Aminotransferase, class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 467.0
TLS3_k127_988659_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 425.0
TLS3_k127_988659_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 378.0
TLS3_k127_988659_4 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000455 250.0
TLS3_k127_992023_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1512.0
TLS3_k127_992023_1 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 473.0
TLS3_k127_992023_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000002383 173.0
TLS3_k127_992023_3 - - - - 0.0000000000000001005 86.0